Digital Commons Network^™

How Do More Diverse Plantings Lead To More Carbon Accrual In Soil?, Haley Rose Wills, Kaylee Grace Duncan, Alexander Constantin Mazareanu

Student Scholar Symposium

No abstract provided.

To What Extent Do Urban Planning Practices Impact Climate Change In Latin America?, Oliver Orellana, Mitchell Roberts

Student Scholar Symposium

Understanding best practices with regards to urban planning and development is crucial to the success of any city. Given the historical, geographic, and economic state of Latin American countries, the role of these practices in innovation is exceedingly vital. By analyzing sustainability strategies employed in cities to mitigate the effects of climate change, this research will identify which practices are the most sustainable in the long run. Because Latin American countries face their own unique challenges in areas like democratic transition, physical landscape, or economic well-being, gaining understanding as to which practices would most benefit the region is pivotal to …

Validating Pharmacogenomics Generative Artificial Intelligence Query Prompts Using Retrieval-Augmented Generation (Rag), Ashley Rector, Beth Breeden, Jay Dorris

Student Scholar Symposium

This study evaluated the performance of Sherpa Rx, an artificial intelligence platform leveraging large language models and retrieval-augmented generation (RAG) for pharmacogenomics, by validating its performance across key response metrics. Sherpa Rx integrated Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines with Pharmacogenomics Knowledgebase (PharmGKB) data to generate contextually relevant responses. A dataset (N=260 queries) spanning 26 CPIC guidelines was used to evaluate drug-gene interactions, dosing recommendations, and therapeutic implications. In Phase 1, only CPIC data was embedded; Phase 2 additionally incorporated PharmGKB. Responses were scored on accuracy, relevance, clarity, completeness (5-point Likert scale), and recall. Wilcoxon signed-rank tests compared accuracy between …

Bcl-2 Regulation As Seen In Alzheimer's Disease, Whitley Whitehead, Joseph Marek, Jack Lowry, Parker Shirley

Student Scholar Symposium

Alzheimer’s Disease (AD) is a degenerative and destructive disorder causing progressive impairment and loss of the nerve cells, eventually leading to further impairments of cognitive functions. Calcium ions (Ca2+) are vital for cell signaling and muscle contraction. The Bcl-2 protein family helps regulate cell death by controlling the release of Ca2+ from the ER. Bcl-2 can also block pro-apoptotic proteins from puncturing the mitochondria and causing intrinsic apoptosis. In AD, the presence of amyloid-beta plaques and neurofibrillary tangles downregulates Bcl-2 production. The loss of Bcl-2 leads to mitochondrial damage, heightened calcium levels, and oxidative stress. Although there is no cure …

The Star Compass, Megan Gables

Student Scholar Symposium

In Megan Gables’ manuscript, The Star Compass, Gables’ character, Cole Summers, endeavors to prepare for grad school, but she is rejected by her dream program, the London Lost Tribe College of Archaeology. Even though her application has been denied, Cole discovers that she will be allowed to participate in an archaeological expedition funded by the London Lost Tribe College of Archaeology. The expedition would attempt to follow a compass that some claim can navigate star charts and is rumored to have been involved in actions regarding World War II. Cole fears joining the expedition, because she suspects that the …

The Creation And Continuation Of The Elvish Language, Megan Gables

Student Scholar Symposium

J.R.R. Tolkien’s Lord of the Rings, published in the 1950s, stands apart for its use of Constructed Languages. Tolkien graduated from Oxford University and pursued a career as a professor of philology and linguistics. Tolkien loved using his linguistic expertise to create realistic cultures and communities within his fantasy worlds. One of Lord of the Rings most famous Constructed Languages is Elvish. Tolkien’s inspiration for the sound of Elvish with Welsh and Finnish as both languages are highly phonetic. Welsh inspired the stress syllables, while Finnish influenced Elvish’s sound and writing. Since Tolkien’s death in 1973, the Tolkien estate …

Victims Playing Villains: Subjects Of Blame In Elie Wiesel's "Night", Naomi Hollans

Student Scholar Symposium

Many readers who are familiar with the Jewish Holocaust are also familiar with Elie Wiesel’s Night. While many tragedies testify of villains and victims, Night’s testimony on these two elements is unclear. Night is riddled with shame, and Elie often sees himself as a perpetrator in his own suffering. With this misplaced shame, Wiesel partakes in a “confession” at the end of Night. This paper explores each of Wiesel’s “villains” and theorizes the psychological motivations behind each indictment. It gives special interest to the prevalence of victim shame in Holocaust survivor testimony, building on existing research about …

How Ot Is Improving Aspects Of Daily Living In Children With Asd: An Integrated Review, Elizabeth Mearse, Reagan Mcgee, Elshaday Solomon, Zoe Curtis, Larissa Brooks

Student Scholar Symposium

This presentation aims to show how affective Occupational therapy is in improving aspects of daily living in children under 18.

Elucidating The Role Of Hd5 In Colonic Wound Healing, Lavin Radiro

Student Scholar Symposium

Crohn’s colitis (CC), a subtype of inflammatory bowel disease (IBD), causes chronic inflammation in the large intestine, leading to malnutrition, diarrhea, and severe pain. Early and accurate diagnosis of CC is crucial, as misdiagnosis with ulcerative colitis (UC) can result in inappropriate treatment and worsened outcomes. The innate immune peptide human alpha-defensin 5 (HD5) is upregulated in CC but not in UC, suggesting a potential role in disease pathogenesis. Preliminary data from our lab indicates that HD5 impairs wound healing in colonic epithelial cells, but the molecular mechanisms remain unclear.

Hypothesis We hypothesize that HD5 increases RNA and protein levels …

The Nesting Behavior And Habitat Selection Of Wood Thrushes, Amelia Browning, Alexandra Price

Student Scholar Symposium

Wood Thrushes (Hylocichla mustelina) are a species of concern in Tennessee due to many factors. Historically, their nests have been found in low-hanging branches at the edge of dense forest (Evans et al. 2020). In 2021, a Wood Thrush nest was found in Warner Parks, a 3100-acre urban park sixteen kilometers south of Nashville, TN nesting eighteen meters off the ground and thirty meters from an active trail. We wanted to learn if this unusual nest height was a common occurrence in an active area of Warner Parks or an anomaly. We decided to compare nesting behavior and habitats at …

Driving Social Revolutions In 20th Century Latin America, Oliver Orellana

Student Scholar Symposium

This paper explores various definitions of social revolutions to create one cohesive and operationalized definition that measures success through a numerical rating scale. Once establishing what revolutions were successful or fall into different typological sortings, this research employs qualitative content analysis as well as quantitative methods still being refined, in order to investigate the potential drivers of social revolutionary success in Latin America throughout the 20th century. The findings have implications for whether the masses and political movements should pursue this endeavor and when their efforts will have the highest potential and likelihood of success. On the other hand, these …

A Teacher, Medical Advisor, And Comedian Walk Into A Bar: Table For One, Everything Ai Can Do, Lorelai M. Kline

Student Scholar Symposium

As Generative AI continues to rise in popularity, AI chatbots have emerged as a promising solution for addressing students’ real-world needs. This presentation investigates the development process behind a series of specialized, personality-driven AI assistants—created via the Boodlebox platform—and examines how these chatbots enhance educational experiences and practical applications. The research uses progressive design methodologies, including persona development, natural language processing optimization, and user-centric testing protocols. Examples of personal bots include a historical assistant that interprets contemporary social scenarios through an 18th- to 19th-century perspective and a Spanish-speaking chatbot that leverages playful sarcasm to foster deeper engagement. Preliminary findings show …

Investigating The Effects Of Body Composition Assessment On Dietary Intake In Division I Football Players, Cameron Nill, Nicole Dicicco

Student Scholar Symposium

No abstract provided.

Things That Just Happen, Naomi Hollans

Student Scholar Symposium

Naomi Hollans’s nonfiction piece, “Things That Just Happen,” narrates a young woman’s experience with tragedy. After her grandfather’s death from cancer, the young woman receives another shock: her mother is diagnosed with cancer. While her mother endures chemo and the young woman prepares for college, her 4-year-old brother is also diagnosed with cancer. In the midst of these bafflingly painful circumstances, the narrator, her peers, hairdressers, and Sunday school teachers seek an explanation for suffering. Hollans’s reflection examines the human need to understand pain and discusses the various motivations for asking “why?” in response to grief. “Things That Just Happen” …

“In A Relationship”: Can Ai Take The Place Of A Human Relationship?, Hannah Smith

Student Scholar Symposium

This research explores the impact of AI on adolescent development, specifically focusing on how large-language models (LLMs) influence the way adolescents approach and value human connections. While AI can offer some benefits, it cannot fully replace the essential elements of human relationships, such as empathy, creativity, and emotional understanding, which are fundamental to a fulfilled life.

Investigating The Potential Ability Of The Tlr4-Nf-Κb Axis To Reduce Aryl Hydrocarbon Receptor Expression In Intestinal Epithelial Cells, Gabriella Longoria

Student Scholar Symposium

Necrotizing enterocolitis (NEC) primarily affects premature infants and is characterized by intestinal necrosis, inflammation, and high mortality. Toll-like receptor 4 (TLR4)-induced apoptosis of intestinal epithelial cells is thought to drive NEC development. Upon binding bacterial lipopolysaccharide (LPS), TLR4 signaling activates NF-κB, leading to inflammatory gene expression. Indole-3-carbinol (I3C), a pro-ligand of the aryl hydrocarbon receptor (AhR), prevents NEC in a mouse model by downregulating TLR4, despite reduced AhR expression in NEC-affected intestines. However, the molecular mechanism behind the reduced expression of AhR in NEC is unclear. To model NEC in vitro, we treated IEC-6 enterocytes with LPS, which reduces AhR …

Investigating The Role And Mechanism Of Faecalibacterium Prausnitzii In Fatty Acid Metabolism And Obesity Using The Drosophila Melanogaster Model, Jackson Head, Whitley Whitehead

Student Scholar Symposium

The obesity epidemic has increased to enormous numbers with 890 million adults being classified as obese (BMI≥30). Obesity is of extreme concern as it is a comorbidity to coronary heart disease, type-2 diabetes, and cancer. Although obesity has classically been attributed to genetics and lifestyle, there is a growing interest in other factors, including the gut microbiome. Germ-free mice are resistant to weight gain even when placed on a high-calorie diet, establishing that metabolites produced by gut microbiota can dramatically inhibit metabolism. Here, we use Faecalibacterium prausnitzii, which has been previously shown to be reduced in obese individuals; however, …

The Effect Of Hd5 On Colonic Wound Healing, Kaitlyn Sneed

Student Scholar Symposium

No abstract provided.

Domination, Limitation, And Liberation In Gilman's Herland, Ella Cauley

Student Scholar Symposium

No abstract provided.

Indole Improves Outcomes Of Cronobacter Sakazakii Infection In C. Elegans Through Ahr-1, Cayden Durrough

Student Scholar Symposium

Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease primarily affecting premature infants. Toll-like receptor 4 (TLR4)-mediated epithelial damage allows microbial translocation, triggering inflammation that can lead to sepsis and death. The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor, and AhR ligands have been shown to prevent NEC in a mouse model. Indole, an AhR ligand, has been reported to extend the healthspan of C. elegans, and we have shown previously it mitigates poor outcomes in wild-type worms infected with Cronobacter sakazakii (Cs), a bacterial pathogen linked to NEC. We hypothesized that C. elegans must express ahr-1, the ortholog …

Indole Treatment Of C. Elegans Rescues Cronobacter Sakazakii Induced Illness, Joshua Asselin

Student Scholar Symposium

Necrotizing enterocolitis (NEC) is a severe and often life-threatening inflammatory condition of the intestine primarily affecting premature infants. The opportunistic pathogen Cronobacter sakazakii (Cs) has been implicated in NEC. While activation of the ligand-dependent transcription factor aryl hydrocarbon receptor (AhR) has been shown to prevent NEC in a mouse model, its potential as a therapeutic target for established NEC remains unclear. We hypothesize here that the AhR ligand indole can reverse Cs-mediated illness in the model organism Caenorhabditis elegans. Our results demonstrate that exposure to live Cs, but not heat-killed Cs, significantly impaired worm motility, demonstrating Cs is an effective …

Myocardial Pi3k-Akt Pathway And Cardiovascular Disease Etiology, Bryson Lovorn, Brennan Kaplan

Student Scholar Symposium

Cardiovascular diseases (CVD) are the leading causes of death in the United States according to recent data from the Center for Disease Control (CDC). Myocardial infarctions, heart attacks, Coronary Artery Disease, ischemic reperfusion injuries, and hypertrophic cardiomyopathies represent common pathologies leading to the hospitalization of Americans. The etiologies of these diseases vary, however there is a common link. The phosphatidylinositol-3-kinase (PI3K) AKT pathway is a cellular pathway that is commonly overexpressed or repressed in myocytes. The human body is in an active limbo to maintain homeostasis. At a cellular level this can be simplified to a delicate balance between cell …

Hyperbaric Chambers For College Athletes, Alex Pinkston

Student Scholar Symposium

The use of hyperbaric chambers is gaining attention as a beneficial treatment for college athletes, offering a healthier alternative to more common, yet riskier, performance-enhancing drugs (PEDs) and modern pharmaceuticals. While professional athletes often have the financial resources to afford hyperbaric therapy, college athletes face similar intensive training regimens but frequently turn to harmful substances to enhance recovery and performance due to limited access to alternative treatments. This research explores the potential of hyperbaric chambers to support the physical and mental well-being of college athletes, highlighting their role in reducing recovery time, enhancing tissue repair, and improving overall performance. Furthermore, …

Traffic Study, Kennedy Case, Koryn Harms, Min Kaung, Abel Assefa, Eli Lockert, Dj Church

Student Scholar Symposium

No abstract provided.

Nashville Bus System Efficiency, Koryn Harms

Student Scholar Symposium

Nashville’s recently approved “Choose How You Move” plan creates a dedicated funding source for transportation improvements in the city. A key component of the plan is to increase transit service throughout Nashville to make it more accessible and reliable. In order to optimize the use of the funding, an analysis of existing conditions would allow officials to locate and target specific areas in need of improvement. The aim of this research is to determine the efficiency of different bus routes in Nashville based on ridership and on-time rates. The analysis will focus on the eight primary bus routes in the …

In Pregnant Women, What Is The Effect Of Nutritional Guidance And Intervention On Maternal And Fetal Health Outcomes Compared With Standard Or No Nutritional Counseling Within The Prenatal And Postpartum Period?, Kaitlyn Boyer, Ainsley Cash, Mallye Merritt, Meagan Enbody

Student Scholar Symposium

No abstract provided.

Effect Of Nutritional Guidance And Intervention On Maternal And Fetal Health Outcomes, Kaitlyn Boyer, Meagan Enbody, Mallye Merritt, Ainsley Cash

Student Scholar Symposium

Title: Effect of nutritional guidance and intervention on maternal and fetal health outcomes

Short Title: Impact of nutrition guidance on maternal and fetal health

Keywords: nutritional guidance, pregnancy, pregnancy outcomes, maternal and fetal health, nutrition teaching

Syllabus Tone And Student Self-Efficacy, Natalia Calderon-Hernandez, Alan Avila

Student Scholar Symposium

Educational research has indicated that Syllabus documents have the potential to communicate equitable policies and clear the path for positive educational experiences (Artze-Vega et al., 2023). Changes to syllabus language, such as warm tones, increase the likelihood that students will ask the professor for help (Gurung & Galardi, 2022). Our proposal is to compare the use of language targeted toward these learner-centered principles within a syllabus document, as compared to traditional cold “content-focused” language, to assess outcomes of perceived student self-efficacy. After viewing two syllabi documents, participants complete portions of The Academic Self-Efficacy Scale (Chen, Hsiao, Chern & Chen, 2014) …

Gaylord Opryland Congestion Reduction, Kennedy Case

Student Scholar Symposium

Lipscomb University’s College of Engineering is working collaboratively with Gaylord Opryland Resort and Convention Center to explore potential solutions to its traffic congestion problem, particularly during peak times such as the holiday season. This research aims to identify strategies that can alleviate congestion in the resort area. With over one million visitors during the holiday season each year and limited parking capacity, the traffic congestion poses a significant challenge to both operational efficiency and visitor experience. The primary objective of this research is to identify strategies that optimize parking usage, reduce congestion, and improve the overall visitor experience. Beginning with …

Association Between The Diet Of Adolescents In America And The Prevalence Of Depression Found Within This Population, Mary Hoffman, Belinda Asamoah, Fadeyemi Okewusi

Student Scholar Symposium

Poor nutrition and lack of physical activity increase the risk of chronic mental and physical health conditions such as depression and obesity in American adolescents. Depression is the leading mental illness found in adolescents across the United States and less than 1 in 10 children eat their recommended vegetables, only 16 % of adolescents meet U.S. physical activity guidelines, 36.3% consume fast food on a given day, and as many as 20% are obese. These numbers show a rapid rise along with the availability of fast food. Multiple studies examine the relationship between healthy nutrition and the signs and symptoms …