Digital Commons Network^™

Dosimetric Validation Of An Electron Monte Carlo (Emc) Algorithm For Small Cutouts And Extended Ssd’S: Assessing Emc In Small Field Dosimetry, Anil Basavaaraju

Theses and Dissertations

This thesis validates the accuracy and limitations of Electron Monte Carlo (eMC) simulations in Eclipse treatment planning systems for small-field electron dosimetry and extended source-to-surface distances (SSDs). Systematic measurements were performed using a microDiamond detector across various electron energies and field sizes. The study examines the discrepancies between measured and calculated (eMC) dose distributions, validating challenges due to lateral scatter disequilibrium and extended air gaps. Our findings provide systematic data for eMC dose calculations and demonstrate that eMC performs within clinical tolerances, with the ultimate goal of enhancing the precision and safety of radiation treatments.

The Influence Of Gender Identity And Healthcare Delivery Experience On Hiv Screening, Delton Harris

Theses and Dissertations

This dissertation examines the roles of gender identity, healthcare experience, and practitioners' scope of healthcare services in the uptake of annual HIV screening among the understudied population of transgender individuals. Transgender individuals are about half as likely to have an annual HIV screening despite having similar risk profiles to men who have sex with men (MSM). The current HIV guidelines for MSM recommend annual HIV screening because of the risky sexual practice, anal sex with other men. Similar to MSM, transgender individuals who have anal sex with men are at higher risk than the general population for HIV acquisition because …

Assessment Of Drivers Of Light Attenuation In Virginia Reservoirs, Jackson Barnett

Theses and Dissertations

Water clarity in aquatic ecosystems is crucial for submerged vegetation and algal dynamics. We investigated the factors influencing light attenuation (kd) by measuring total suspended solids (TSS), chlorophyll-a (CHLa), and chromophoric dissolved organic matter (CDOM) across thirteen stations located in seven reservoirs. Average kd was 1.69 m^-1 (range: 0.37-3.99 m^-1), with photic depths averaging 3.27 m (range: 1.15-12.43 m). TSS was the primary predictor of light attenuation (R² = 0.57, P = 0.003, SE = 0.053). Average TSS values for each site were multiplied by the slope of the kd-TSS relationship to find the proportion of kd …

Infinite Finite: A View On Human Progression Through Emergent Generative Systems, Fatima Abbas

Theses and Dissertations

Contemporary crises reveal an imbalance in human progression, prioritizing material advancement while neglecting ethical, compassionate, and spiritual dimensions. This thesis examines natural progression through the lens of emergence, where simple interactions produce complex outcomes. Analyzing natural patterns across different scales, from cosmic formations to neural interactions, underscores emergence's universal nature.

Within this context, Infinite Finite introduces a generative digital tool simulating emergence through iterative cycles of construction and deconstruction. Depicting a century of human progression informed by historical behaviors via simulated cellular interactions, the tool visually differentiates ethical from unethical progression. This is represented through ten data visualization tiles composed …

¡Bip Bip!, Diego Pablo Málaga Beckhart

Theses and Dissertations

¡Bip Bip! is a body of work that investigates the car as it exists in the American imagination, a metaphorical and physical object where culture, identity, and power intertwine. This work uses painting, printmaking, collage, video, and installation to explore the car as a space of expression, interiority, and understanding the world through a marginalized lens.

Central to my practice is my personal vehicle, Guadalupe, which functions as both muse and metaphor, the main driver of the framework within ¡Bip Bip! My practice examines the different but congruent contexts intersections of this iconic American symbol, the car. In my paintings, …

Subgingival Microbiomes Of Healthy And Periodontitis Subjects, Tareq Abdulrasoul

Theses and Dissertations

Background: Periodontitis is a common chronic inflammatory disease triggered by the dysbiosis of the subgingival microbiome. 16s rRNA sequencing has been used to profile the subgingival plaque samples in healthy and periodontitis subjects. Here, we have collected subgingival plaque samples from subjects and analyzed the microbiome profile from 16s rRNA sequencing. We hypothesized that periodontitis patients will have a different subgingival microbiome profile than that of healthy subjects.

Methods: Subgingival plaque samples were collected from periodontitis and healthy subjects who were indicated for periodontal surgeries (osseous resective and regenerative surgery for periodontitis patients or crown lengthening for healthy …

Beneath The Roots: Becoming Native Through Mangrove Teachings And Wisdom, Shima Aeinehdar

Theses and Dissertations

Beneath the Roots uses the wisdom of mangroves to investigate the naturalization of humans through science, spirituality, and storytelling. The seeds of Avicennia marina, the gray mangrove, drifted to Qatar at some point in history and took root, like so many other people here. The mangrove survives in a harsh saline environment through a unique salt excretion process. As a Qatar-born expat, I relate to this struggle to survive and nativize in a land that is both my own and foreign to me, in a cyclical conversation. I explore this nativization process through a ritual of salt extraction, creating botanical …

Crafting Futures: Balancing Tradition And Technology In Craft Practices, Saga Elkabbash

Theses and Dissertations

Under pressure from mass production and the decline of artisan skills, craft traditions risk becoming relics of the past. Crafting Futures challenges this by treating machines as tools of creative expression, working alongside and in harmony with traditional hand techniques. By pairing an experienced potter with a creatively deployed 3D-printer to develop a series of artifacts, this research fosters a dynamic conversation between partners. Digital fabrication can engage with, rather than replace, traditional making practices, emphasizing the role of the maker’s imagination as the site of knowledge, intuition, and improvisation. The resulting series of hybrid clay vessels reinforce not only …

Development Of A Mediation Model Of Pain Cognition In Adult Patients With Sickle Cell Disease, Daniel M. Sop

Theses and Dissertations

Pain is a hallmark of Sickle Cell Disease (SCD), a genetic hemoglobinopathy characterized by chronic hemolytic anemia, vaso-occlusion, and organ damage. While acute vaso-occlusive crises (VOC) have been extensively studied, the mechanisms underlying chronic pain and its interplay with brain function remain unclear. This dissertation investigates the relationships between cerebral blood flow (CBF), fluid cognition, and pain sensitivity in adults with SCD, utilizing advanced imaging techniques and validated assessment tools.

Arterial spin labeling (ASL) and functional magnetic resonance imaging (fMRI) were employed to measure CBF and brain activity, respectively. Pain sensitivity was assessed using the Pain Sensitivity Questionnaire (PSQ), and …

The Trauma-To-Prison Pipeline: A Multi-Level Theoretical Framework Exploring The Intersection Of Inequality, Trauma, And Exclusionary Discipline, Dana Ainsworth

Theses and Dissertations

The school-to-prison pipeline (STPP) is a widely recognized and extensively studied metaphor used to describe the process by which school discipline policies increase the risk of juvenile justice system involvement, particularly among historically marginalized populations. While it has been instrumental in shaping educational policy, the STPP framework has not evolved to account for the critical impact of trauma on learning and behavioral outcomes. Furthermore, it overlooks the role of systemic inequality that increases trauma exposure and produces concentric patterns of marginalization.

Drawing on research across the fields of education, public health, sociology, and criminal justice, this study proposes a theoretical …

Development, Synthesis And Characterization Of Advanced Low- Cobalt And High-Nickel Cathode Materials For Lithium-Ion Batteries, Arjun Patel

Theses and Dissertations

This dissertation focuses on the improvement of structural and electrochemical stability of active materials for lithium-ion batteries. It explores the modification strategies to mitigate the issues related to Ni-rich cathode materials, along with the continuous production of cathode precursors using a slug flow reactor to improve the quality of the product.

The First part of the dissertation examines the effect of substitution of cobalt with aluminum and iron on the electrochemical stability of Ni-rich lithium nickel cobalt manganese oxide (NCM) materials. This study investigates how Al and Fe doping work and how they impact the performance and stability of these …

Immersive Medical Practice And Clinical Training: Virtual And Mixed Reality In Pharmacy And Orthopedic Surgery, Silas Semprini De Toledo Contaifer

Theses and Dissertations

Extended‑reality (XR) technologies including virtual reality (VR) and mixed reality (MR) offer new ways to improve training and surgical precision. This thesis evaluates their educational and clinical impact through two complementary studies.

Specific Aim 1 compared an immersive 360° video VR module with conventional training for teaching USP < 797> sterile‑compounding skills to second‑year PharmD students (N = 36). VR trainees raised their knowledge from 6.14 ± 1.55 to 8.69 ± 1.07, yet the overall post‑test advantage versus control was not statistically significant (U = 71.50, p = 0.21). Item‑level McNemar testing showed significant VR‑exclusive gains on three critical questions (K5, K6, …

Amplifying Student Voices: A Case Study On The Writing Workshop In A 10th Grade English Classroom, Erin S. Drulis

Theses and Dissertations

This qualitative case study explores how a white, second-year 10th-grade English teacher implemented a culturally affirming version of The Writing Workshop in a private high school serving primarily Black and Latine students from working class families. Through a yearlong collaborative coaching partnership between the researcher and teacher, this study examined how writing instruction might elevate student voice in writing instruction. Grounded in a pragmatic interpretivist epistemology and supported by five intersecting theoretical lenses—democratic education (Dewey), sociocultural constructivism (Vygotsky), culturally affirming pedagogy (Ladson-Billings), critical pedagogy (Freire), and radical love (hooks)—this case study investigated how students used writing as a means of …

Guardians Of Their Own: Routine Activities, Risk Perceptions, & Self-Protection Among Police Officers In The Line Of Duty, Amy Clifton-Mills

Theses and Dissertations

This research illuminated how police officers perceive risks in the line of duty and whether police officers implement protective behaviors on duty. This was done by implementing two phases of data collection: focus groups (I) and self-report surveys (II). The focus groups (N = 21) were conducted to inform the self-protective behaviors instrument in the self-report surveys (N =143). Officers self-reported their risk of assault and injury in the line of duty in the next six months to be 33.86% (SD = 27.13) and their risk of felonious death to be 14.4% (SD = 18.1). Results show that …

Investigating The Temperature Effects On Aedes Aegypti And Dengue Virus In Central Argentina: Perspectives From Mathematical Modeling, Morgan H. Jackson

Theses and Dissertations

Dengue virus (DENV) causes over 390 million infections and around 40,000 deaths worldwide each year. DENV is primarily transmitted by the mosquito Aedes aegypti, and both the life cycle of these mosquitoes and DENV transmission are significantly impacted by temperature. In the temperate region of Central Argentina, where dengue outbreaks first began in 2009, outbreaks only occur following new introductions of DENV from other regions. Due to the relationships between temperature and DENV and temperature and Ae. aegypti, the risk of an outbreak changes throughout the year. Here, we develop and analyze mathematical models for both mosquito population dynamics and …

Teaching Under Political Influence: A Multiple Case-Study Examining The Impact Of Curricular Restriction Policy On Community-Connected Instruction (Cci) In Full-Service Community Schools (Fscs), Isaiah Moore

Theses and Dissertations

Scholars describe the political landscape as polarized, where partisanship —loyalty to a particular political party— dictates one’s beliefs. In education, this partisanship is best exhibited through conservative policy restricting curricula regarding race, racism's pervasiveness, gender identity, and how history is taught in public schools. Conversely, Community-Connected Instruction (CCI) affirms students’ culture and builds critical thinking skills in an authentic environment. While studies suggest its benefits to students, the current curricular restriction policy challenges its usage. This form of teaching is closely associated with Full-Service Community Schools (FSCS), which primarily serve underserved student populations. This study examines how FSCS educators in …

Queer-Keying: Performing Video Processes As [Trans]Gressive Resistance, Wren Tiffany

Theses and Dissertations

As part of the 2025 VCUarts MFA Thesis Exhibition at the Institute of Contemporary Art (ICA) at Virginia Commonwealth University (VCU), I transformed the 'Sponge' gallery on the top floor of The Anderson, VCU’s historic thesis exhibition home, into The Green Room, a neon green, immersive video and performance space featuring mirrors, disco lights, a foam tile dance floor, makeup stations, and a functioning green-screen editing suite. This hybrid drag rehearsal and ‘Chroma-key’ green video production room deepened both my understandings of Queer performance art and process-based art making during the Spring of 2025, through two public performance activation …

Cannabis Use Among Cancer Survivors And The Impact On Cancer-Related Pain, Tiffanie A. Vargas

Theses and Dissertations

With a growing population of older adult cancer survivors—many of whom experience cancer-related pain—interest in medical cannabis as a pain management strategy has increased. This secondary analysis used data from the 2022 U.S. Behavioral Risk Factor Surveillance System (BRFSS) to examine cannabis use behaviors among cancer survivors and assess associations with cancer-related pain. The study had three aims: (1) to describe 30-day cannabis use (prevalence, intensity, and administration routes) by chronic health condition and cancer diagnosis, focusing on non-melanoma skin cancer, melanoma, and other cancers; (2) to compare demographics, health characteristics, and tobacco use by cannabis use status among cancer …

Modeling Synergistic Effects Of Integrin And Tgf-Β Signaling In Epithelial Mesenchymal Transition, Prerak Thakkar

Theses and Dissertations

The induction of Epithelial Mesenchymal Transition (EMT) is initiated by a

number of protiens and growth factors, one of which is the profibrotic cytokine Trans-

forming Growth Factor β (TGF-β). Within the extracellular matrix (ECM), TGF-β

is found in a latent, inactive form bound to proteins such as fibronectin (FN). For

TGF-β to contribute to EMT induction, it has to be extracted from the latent com-

plexes into a soluble form. This soluble, activated TGF-β can then bind to receptors

on the cell membrane, which causes the transduction of signals that begin EMT. Re-

search has shown that the release …

Inherited Wounds: Navigating Intergenerational Trauma Through Cooperative Play, Ayza Sheikh

Theses and Dissertations

'Strength' for Pakistani women is often defined as compromise, sacrifice, and silence. This definition has shaped intergenerational struggles in which women's self-narratives are constructed through suppression. Inherited Wounds seeks to address the trauma of suppression by creating a safe space for expression that fosters reflective and emotion-driven dialogue between Pakistani mothers and daughters.

Using interactive storytelling and embodied play, I developed a choice-based, narrative-driven video game and accompanying gesture-based controller. The game unfolds across childhood, marriage, and motherhood, mirroring the cycle of intergenerational struggle. Navigating choices in the game requires physical, intimate cooperation. The game uses the protagonist’s life as …

The Bitch And The Boogeyman: Violence Against Women And Gendered Morality In American Slasher Films, Davis A. Smith

Theses and Dissertations

This research examines the relationships between on-screen depictions of violence in American slasher horror films and depictions of gendered morality of victims. Slashers are a subgenre of horror film that arose out of the exploitation cinema movement of the 1970s that are characterized primarily by the presence of one or more human killers inflicting violence on a group of protagonists, typically through the use of bladed weapons. Data collected comes from a comprehensive set of thirty-six American slasher films that received a wide theatrical release, with exemptions for films whose primary genre is not slasher and only selecting three films …

Food Waste Renaissance: From The Table, For The Table, Yasamin Shaikhi

Theses and Dissertations

What if waste could be seen as a valuable resource rather than a burden? Food Waste Renaissance (FWR) explores innovative ways to transform excess food and byproducts into sustainable design materials. In Qatar, where food waste constitutes approximately 60% of urban waste, FWR promotes a shift in perception rather than attempting to resolve large-scale waste management issues. By fostering a culture where surplus becomes a resource, it inspires individuals, designers, and communities to embrace and contribute to a circular economy. FWR examines rice and date byproducts as biodegradable raw materials for lamps, bringing material from the table back to the …

Existing In The Context: A Conjunctural Analysis Of Kamala Harris Memes, Amaya Mcneal

Theses and Dissertations

Political memes have become a common way for people to express their political views online, helping politics reach young adults who weren’t previously interested. Consequently, politicians have begun sharing and creating memes themselves. The memeification of American politics has diminished debate about ideas, ideals, issues, and people’s vital interests, debasing voters by treating them not as citizens but as passive “consumers” and “spectators” of mediated politics. This paper helps make sense of this crisis, focusing on the example of former Vice President Kamala Harris. Vice President Kamala Harris' memeified presidential campaign during the 2024 U.S. election targeted voters through a …

The Page And The Stage: How Comics Perform, Elizabeth Buccella

Theses and Dissertations

Comics and theatre share several, often overlooked similarities, like their unique concept of the gaze, interpretation and execution of a script, and the curation of a distinct visual language. This makes comics a viable candidate for analysis using the field of performance studies and other theatrical forms of analysis. The process of comics and how they are read is discussed before a brief literature review of performance and comics studies scholarship. Two comics, one nonfiction and one fiction, are analyzed using the key concepts from the literature review.

Investigating Mitochondrial Stress Response Mechanisms In Aging, Aileigh E. Daniel

Theses and Dissertations

Mitochondrial dysfunction is widely recognized as a key contributor to aging and age-related diseases. The concept of mitohormesis suggests that low levels of ROS can activate stress-responsive transcription factors, promoting adaptive mechanisms that enhance longevity. We hypothesized that changes in protein abundance under conditions of mild mitochondrial stress reflect an adaptive response, and that commonly altered proteins across diverse genetic backgrounds of mitochondrial stress can help identify key regulators of stress resilience and aging. Our study identified conserved mitochondrial stress response pathways and highlighted candidate regulators for further investigation. These regulators appear to impair mitochondrial energy production by downregulating ATP …

Orb Weaver, Quinn Standley

Theses and Dissertations

Orb Weaver is a 24-minute experimental video/lm. This essay does not explain its meaning, as viewers should feel the power to trust their own interpretations. Instead, it reflects on the process of making the lm interwoven with autobiographical thoughts.

Substrate Preference And Foraging Behavior Of Two Declining Warblers In Appalachian Shrublands, Samantha Fishman

Theses and Dissertations

Abstract Shrubland and early successional habitats (ESH) support a diversity of wildlife, including many declining songbirds. However, nonnative shrubs increasingly dominate these habitats, potentially altering habitat quality by influencing prey availability. Habitat quality can be assessed by observing foraging behaviors of songbirds and identifying preferred and avoided substrates as well as testing the predictions of optimal foraging theory; specifically that birds will maximize their energy gain relative to the costs. We examined foraging behaviors of Golden-winged Warblers (Vermivora chrysoptera; GWWA) and Chestnut-sided Warblers (Setophaga pensylvanica; CSWA) in ESH on private lands in Virginia with varying amounts …

I Love Getting Mad At The Internet, Tariye George-Phillips

Theses and Dissertations

This book discusses the changing ecosystem of the internet in relation to my installation ‘In These Worlds’. This is not a direct translation of the installation, but shares the research and thought that informs the work, as well as sharing some of the work that preceded.

Strength Imbalances And Shoulder Pain In Manual Wheelchair Users Stratified By Age Of Spinal Cord Injury/Disorder (Sci/D) Onset, Ashlyn M. Jones

Theses and Dissertations

Introduction The majority of manual wheelchair users (MWUs) with spinal cord injury or disorder (SCI/D) develop shoulder pain. In adults with SCI/D, there is evidence that upper limb strength imbalances are associated with shoulder pain. However, strength imbalances may indicate protective compensatory strategies, and other factors may be important contributors to pain. Currently, personalized prevention and management of pain is limited, little is known about joint strength imbalances and pain in children who use manual wheelchairs, and the effect of the age of SCI/D onset is poorly understood. The purpose of this study was to assess the effect of age …

Unleashing Serine Palmitoyltransferase In Test Tubes And Mice, Matthew W. Peart

Theses and Dissertations

Canonically known both for structural contributions to lipid bilayers and roles in cell signaling, the sphingolipids comprise a dynamic, multifaceted class of molecules which are studied to understand homeostatic cell biology as well as pathophysiology. Sphingolipids contribute to tissue-specific structures such as myelin, a multilayer membrane that allows for rapid conduction of action potentials along neuronal axons. All sphingolipids are downstream products of the rate-limiting and initiating enzyme in the de novo sphingolipid synthesis pathway, Serine palmitoyltransferase (SPT). Demonstrative of its status as the enzyme that catalyzes a crucial step in a biochemical pathway, SPT activity is strictly regulated. This …