Enhanced Optimization Of Mass Transfer For Carbon Capture And Wastewater Remediation In Algal Systems Through Algorithmic And Bioprocessing Techniques, Peter Ofuje Obidi

Doctoral Dissertations

The scalability and industrial deployment of algal cultivation systems are limited by suboptimal mass transfer, constraining their effectiveness in carbon capture and wastewater remediation. This research investigated these challenges through integrated optimization methodologies that combine algorithmic frameworks with enhanced bioprocessing techniques to enhance efficiency, economy, and scalability. A System-of-Systems (SoS) meta-architecture was developed using genetic algorithms and fuzzy assessor functions to demonstrate a pathway toward cost reduction. Rigorous mechanical and chemical characterizations were quantitatively analyzed to reveal existing optimization strategies and further evaluated the best strategies to use in enhancing mass transfer for improved biomass yield. The work also integrates …

Tailoring Selected Aerogels To Targeted Applications, Stephen Yaw Owusu

Doctoral Dissertations

Aerogels are ultra-lightweight, porous solid materials characterized by a three-dimensional nanostructured network. Owing to their exceptional physical and chemical properties, aerogels have garnered considerable attention within the materials science community and were recognized by IUPAC in 2022 as one of the top ten emerging technologies in chemistry. Although numerous aerogels have been synthesized, only a few have been effectively tailored for specific applications. Optimizing the properties of known aerogels for targeted uses remains challenging. This dissertation investigates strategies for tailoring aerogels derived from isocyanate-benzoxazine, benzodiazine, and phenolic resins to meet the requirements of various advanced applications. The approaches employed include …

Towards The Faa's Next Century: Clarifying Disclosure Requirements In Arbitration, Andrea K. Schneider, Brian Farkas

Articles

This essay provides a roadmap to the current landscape of neutrality and disclosure. It then suggests three possible reforms to the FAA that would provide better guidance to arbitrators, parties, and courts. Moreover, this essay argues that if the FAA cannot be sufficiently amended, states should take the lead. States can continue to more clearly outline disclosure requirements and enforce clearer standards than the current version of the FAA.

Avenues For A Number Density Interpretation Of Dihadron Fragmentation Functions, T. Rogers, A. Courtoy

Physics Faculty Publications

In this letter, we reassess the underlying physics of the number sum rule for dihadron fragmentation functions. We will argue that, currently, there are no settled constraints on what constitutes a valid number density interpretation for multihadron fragmentation functions. Imposing overly restrictive criteria might lead to misinterpretating the data. Most importantly, and on the basis of phenomenological analyses, the slightly varying definitions used in previous work are not excluded from possessing legitimate number density interpretations (up to the usual issues with ultraviolet divergences and renormalization), so long as they are paired with appropriate factorization theorems. We advocate for further theoretical …

Community Belonging: Experiences Of Outsiderness In Appalachia, Erin Hudnall

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study demonstrates the potential long standing social impacts of extractive industries in Appalachia, supported by historical data and literature that defines the region as a sacrifice zone or as resource cursed. As represented by key informants and the communities under observational study, West Virginia communities can exhibit dynamics indicative of collective trauma that is emplaced and complex in nature, given a historical high level of industrial intervention and social control that induced precarious economic, environmental, and social circumstances. Some of the main “symptoms” of this collective trauma are an aversion to outsider intervention and nostalgia about the past that …

Bargaining For Statehood: The Intersection Of Capitalism And Politics In The Creation Of West Virginia, Kristen L. Bailey

Graduate Theses, Dissertations, and Problem Reports (ETD)

This project explores the original architecture of West Virginia. The plans and deliberate construction of the new state not only represented the longstanding desire of western counties for equitable representation in its legislature but also rested on the economic and political ambition of the movement’s leaders. Not all western counties supported independent statehood, and a substantial number of counties favored secession. Without a cohesive citizen consensus to embark upon statehood, traditional narratives that the western counties embarked on statehood solely to protect republican interests bears further investigation. Lacking a unified front, political and business leaders steered the movement through the …

An Investigation Into How The Prostate And Androgens Mediate Greater Levels Of Uric Acid In Males Compared To Females, Rachel D. King

Graduate Theses, Dissertations, and Problem Reports (ETD)

Chronic elevated circulating uric acid (UA) levels (hyperuricemia) are associated with gout as well as cardiovascular, metabolic, and renal dysfunction. Men have greater mean circulating UA levels than women and are more likely to exhibit hyperuricemia. This may be partly driven by the hormonal regulation of renal UA transporters; however, a direct link between hormones and UA production has not been established. Production of UA is catalyzed by xanthine oxidoreductase (XOR / XDH), which is ubiquitously expressed but has the greatest specific activity in the liver. Interestingly, an extensive gout genome-wide association study (GWAS) recently revealed a robust genetic …

Mourning And Haunting In Irish Gothic Fiction From The Victorian Era To Modernism, Wenyu Kong

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation explores how three Irish modernist writers, Elizabeth Bowen, Dorothy Macardle, and James Joyce, incorporate and reimagine tropes from the Victorian Gothic Revival to address Ireland’s uneven modernity in the first half of the twentieth century. I argue that the Irish Gothic tradition is essential for these writers to express their reflection and reaction to ongoing cultural and social turmoil in Ireland’s process of modernization during the foundation of the postcolonial Irish state. Extending Sheridan Le Fanu’s Big House Gothic legacy, Elizabeth Bowen creates haunted spaces in The Last September (1929) to describe Anglo-Ireland’s precarious situation during the War …

Enhancing Pillar Stability Assessment In Underground Limestone Mines Using Lamodel: Integrating Empirical Strength Equations For Improved Ground Control, Alim Elibol

Graduate Theses, Dissertations, and Problem Reports (ETD)

Underground stone mining accounts for approximately 21% of all underground mining operations in the United States, with more than 2,000 workers employed in this sector as of 2019. Ground control failures, particularly those involving massive pillar collapses and roof falls, pose significant safety hazards, contributing to 40% of fatalities and 15% of lost workdays since 2006. Several massive pillar collapses have occurred in active limestone mines from 2015 to 2021, and a fatal incident was reported in January 2022 in a mine operating within the Loyalhanna formation. Given these risks, accurate stability assessment tools are essential for improving mine safety. …

Rifles And Riflemen: Material Culture, Violence, And Early American Identity, 1720 -- 1820, John Bradstreet Weaver

Graduate Theses, Dissertations, and Problem Reports (ETD)

The rifle was one of many material objects which colonists of British North America brought with them from Europe. Starting in the early eighteenth century, German-speaking settlers in Pennsylvania began to manufacture rifles from locally made and imported parts. These rifles became associated with other material objects – namely a system of dress, which included wearing a whitetail deer’s tail in the hat, the hunting shirt, and forms of Native American dress – which became emblematic of some British colonists who used rifles in hunting and war. Rifles became militarily important in the Seven Years’ War, where Native American warriors, …

Not Everyone Believes Sports Are A Safe Space: Development Of A Toxic Sports Fandom Scale, Thomas Dean Bobbitt

Graduate Theses, Dissertations, and Problem Reports (ETD)

Dysfunctional Fan Behavior is a concept developed by Wakefield & Wann (2006), that describes fan conduct, consisting of complaining and confrontation, that ruins the experience of sporting events for others. However, there is some evidence that although the items featured in the Dysfunctional Fan Behavior Scale are perceived as negative, they are also viewed as relatively normal and appropriate of sports fans. Bobbitt et al.’s (in press) qualitative analysis suggests that these behaviors are not always considered destructive or toxic in the context of sport, but the line between benignly rude and genuinely antisocial behavior is somewhat difficult to define. …

20 Years Of Light Pentaquark Searches, Moskov Amaryan

Physics Faculty Publications

In this paper, I pay tribute to my exceptional colleagues and friends Dmitri Diakonov, Victor Petrov, and Maxim Polyakov by examining the experimental progress and current status of the searches of the ϴ⁺ pentaquark from its inception to the present.

The People Of The North: Influencer Histories And Miniaturization In Eleventh-Century Italy, Evan Anthony Simonetti

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Norman invasion of Italy in the eleventh century was a process that required political support and legitimacy for its leaders, the Hauteville dynasty. The members of this dynasty either commissioned or financed three individuals as they wrote three respective histories of the Norman conquest in order to accomplish this legitimation. In these sources, each author took inspiration from the classic works of history and poetry of the Greek and Roman world and applied symbolism and direction from their understanding of medieval Christian theology. In addition, these works catalogued examples of events, people, places, animals, and behavior as exotic objects …

P23h Rhodopsin Accumulation Disrupts Synaptic Protein Levels In Rod Photoreceptors, Samantha Thompson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Rod photoreceptors are specialized neurons located in the retina, the neural tissue that lines the back of the eye. Rod photoreceptors are necessary for dim light and peripheral vision through the photoactivation rhodopsin (Rho). Rho is synthesized in the inner segment of rods before being unidirectionally trafficked to the outer segment. In diseases such as retinitis pigmentosa (RP), Rho trafficking can be disrupted, leading to progressive rod cell death. In many cases of RP, Rho is mislocalized to the rod photoreceptor synapse (“spherule”). The impact of Rho mislocalization on spherule structure and protein organization is poorly understood. We hypothesize that …

Simulated Slot Machine Gambling In Relation To Sign-Tracking, Polina Krom

Graduate Theses, Dissertations, and Problem Reports (ETD)

The propensity to attribute incentive salience to reward-related cues, or sign-tracking (ST) has been linked to addiction in animal models and some initial human data. The current study explores the role of sign-tracking (ST), as a potential risk factor for problematic slot machine gambling, which abundantly features audiovisual reward-related cues, henceforth sensory features. A sample of healthy participants without gambling problems (n = 30) completed a Pavlovian-to-Instrumental Transfer (PIT) paradigm to assess ST propensity and played on a realistic slot machine simulator consisting of two versions: with sensory features (SF+) and without (SF-). Each game version had fixed bet sizes, …

Not Far Enough: The West Virginia Human Rights Commission And The Civil Rights Movement, David Solomon

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis investigates the West Virginia Human Rights Commission and its action surrounding the Civil Rights Movement. The Commission represented the liberal ideals that led white moderates to be potent allies of the Civil Rights Movement. Throughout the years following its inception, the Commission investigated and documented many instances of Jim Crow that were crushing Black communities in West Virginia. However, the limits of its liberal approach prevented it from creating solutions that would address the power structures that supported discrimination in West Virginia. By the late 1960s, Black frustrations with the lack of meaningful change boiled over into riots …

From Sequencing To Conservation: Genomic Analysis Of Three Sportfish Species In West Virginia, Andrew Johnson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Situated in the Appalachian Mountains, one of the oldest mountain ranges on Earth, West Virginia waters boast rich ichthyofauna including native sportfish species walleye (Sander vitreus), largemouth bass (Micropterus nigricans), and muskellunge (Esox masquinongy). These three species are all native to the contemporary Ohio River watershed and play a major recreational and ecological role in local fisheries. Ecologically, all three species are apex predators and play a key role in ecosystems by directly influencing local fish assemblages. As dominant apex predators all three species are highly sought after in recreational fisheries with largemouth bass …

Mineralogical And Geochemical Assessment Of Rare Earth Element And Other Critical Mineral Occurrences In Coal-Derived Materials For Resource Recovery Potential, Sai Hemanth Kancha

Graduate Theses, Dissertations, and Problem Reports (ETD)

Rare earth elements (REEs) and other critical minerals (CMs) are indispensable to modern clean energy, electronics, and defense sectors due to their unique physical and chemical properties. The increasing global demand for these elements—combined with concerns about supply chain disruptions and the environmental impact of conventional mining—has heightened the urgency to identify alternative, sustainable sources. Among various secondary resources, coal-derived wastes such as coal refuse, fly ash, bottom ash, and coal acid mine drainage sludge have emerged as promising feedstocks for REE and CM recovery within the United States.

In this study, a comprehensive mineralogical and geochemical assessment was performed …

Repeatability And Reproducibility Of Minutiae Mark-Up, Lyrek Lockley

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study investigated the repeatability and reproducibility of minutiae mark-up. The use of fingerprints as a mode of identification has been around for thousands of years with contributions from figures like Sir William Hershel, Thomas Taylor, Henry Faulds, Sir Francis Galton and many more. Latent fingerprint impressions can be deposited by the perpetrator of a crime on a variety of surfaces at a crime scene. Many times, fingerprints are the most widely recovered and used evidence from a crime scene. Once fingerprints are collected, they go through the analysis, comparison, evaluation, and verification (ACE-V) process. This study will focus on …

Discovering Appalachia As A Political Place: The Influence Of Appalachian Residence And Identification On Presidential Approval And Environmental Policy Preferences, Michael Bancroft Jones

Graduate Theses, Dissertations, and Problem Reports (ETD)

From poets to political scientists, yearning for a sense of place has motivated both song and research. Appalachia is an understudied place in political science, with previous research inconclusive as to whether the Appalachian region has a separate identity from other parts of the United States (White 2019). Identities may be derived from a sense a place. Alternatively, identities may develop from a sense of group identification with common interests and grievances, and concerns regarding out-group members. Appalachia has a long history of being different and set apart from the United States; and also, has been subjected to identity mobilization …

Reclaiming Revolutionary Relics: How Nineteenth-Century Americans Used George Washington’S Objects To Understand The Civil War, Abbi E. Smithmyer

Graduate Theses, Dissertations, and Problem Reports (ETD)

By combining cultural, memory, and material culture studies, this dissertation examines the ways objects associated with George Washington became instruments within the proxy war over whether the United States or the Confederacy best represented the American Revolutionary era’s principal values of liberty and equality. Exploring monuments, statues, historic homes, relics, and mementoes, as well as antebellum speeches and schoolbooks, letters, diaries, military orders, newspapers, and memoirs, this work demonstrates how the relics linked to Washington and the nation’s founding shaped how the Civil War generation thought about America’s past.

The 250th anniversary of the founding of the United States has …

Assessing And Predicting The Impact Of A Retrofitted Methane Mitigator On Non-Road Large Natural Gas Engines Using Artificial Neural Networks, Augustine Thomas Ojo

Graduate Theses, Dissertations, and Problem Reports (ETD)

Abstract

ASSESSING AND PREDICTING THE IMPACT OF A RETROFITTED METHANE MITIGATOR ON NON-ROAD LARGE NATURAL GAS ENGINES USING ARTIFICIAL NEURAL NETWORKS

Augustine Thomas Ojo

Methane emissions from the oil and gas sector present a pressing environmental and economic challenge, given methane’s high global warming potential and the considerable volumes of unutilized gas lost from industrial processes. This study investigates the impact of a retrofitted methane mitigation system, the Methane Mitigator (M²), on fuel consumption and engine-out emissions in non-road, four-stroke natural gas-powered, lean-burn engines and develops predictive Artificial Neural Network (ANN) models to estimate the resulting engine-out emissions and fuel …

The Dna Methylation Capacity Of The Tsetse Fly: Glossina Morsitans, And Its Integration With Symbiont Nutrient Provisioning, Dylan Forrest Richmond

Graduate Theses, Dissertations, and Problem Reports (ETD)

Tsetse flies (Diptera: Glossinidae) are the vector of trypanosomes (Trypanosoma spp.), which are responsible for African trypanosomiasis, also known as sleeping sickness. African trypanosomiasis is a significant health and economic burden yet remains a neglected tropical disease. As an obligate blood feeder, tsetse flies are reliant on B vitamin supplementation from intracellular Gammaproteobacteria, Wigglesworthia glossinidia. Folate (B9) is essential for tsetse development and reproduction, as well as DNA methylation in animals. As a reversible modification, DNA methylation typically occurs in a CpG dinucleotide context and can alter gene expression via the restriction of transcription. Across insects, the …

Exploring The Ruminal Microbiome And Its Impacts On Feed Efficiency In Beef Cattle, Taylor Simone Sidney

Graduate Theses, Dissertations, and Problem Reports (ETD)

The ability for beef cattle to utilize feed efficiently is a critical determinant for both economic and environmental sustainability in livestock production. However, despite extensive research, the complex microbial ecosystem within the rumen and its relationship to feed efficiency remain incompletely understood. This dissertation explores the physiological and microbial foundations of feed efficiency by characterizing how rumen microbial communities and their functions differ among beef cattle with divergent residual feed intake (RFI) phenotypes and how the RFI status of beef cattle influenced their response to dietary interventions such as supplementation with a Bacillus-based feed additive. In the first study, …

Development Of A Model To Estimate Engine Crankcase Methane Vent Emission Rates, Juan Pablo Rincon

Graduate Theses, Dissertations, and Problem Reports (ETD)

The primary focus of this research is the modeling and validation of crankcase methane emissions stemming from natural gas combustion engines commonly deployed in the natural gas compression industry. The models employed rely on equations predicting the flow rate and composition of losses, typically generated within reciprocating piston-cylinder systems. Since crankcase emissions originate in a piston–cylinder arrangement, multiple variables were considered in this study, including displaced volume, pressure, temperature, flow, and viscosity (with corrections applied to account for the thermal and compositional effects on the mixture of fluids). The initial data for this research was collected during three measurement campaigns …

Lis1 Depletion In Adult Mouse Projection Neurons Causes Neurodegeneration And Severe Neurological Phenotypes, Anne Ventrone

Theses and Dissertations

Proper LIS1 function is crucial for human brain development, as mutations in LIS1 lead to lissencephaly, a severe neurodevelopmental disorder caused by defective proliferation, differentiation and migration of neural precursors. Our understanding of LIS1's functions after brain development is limited. LIS1 regulates cytoplasmic dynein 1 (dynein), an essential microtubule motor protein in cell division and migration, but also a cellular transport motor. We previously showed that tamoxifen (TX)-induced global knockout of LIS1 using a Cre/Lox system (Act-Lis1iKO) in young adult mice results in severe neurological defects and rapid lethality. This strongly supports LIS1's critical post- developmental role, but the underlying …

Biochemical And Molecular Analysis Of Anr-Dependent Microoxic Fitness Factors In Pseudomonas Aeruginosa, Stacie E. Balsam

Dartmouth College Ph.D Dissertations

Pseudomonas aeruginosa is a prominent opportunistic pathogen that is often found in microoxic environments like sites of infection and colony biofilms. P. aeruginosa can grow at oxygen (O2) at concentrations as little as 3 μM and also grows anaerobically by generating energy using nitrate as an alternate electron acceptor. An important way P. aeruginosa adapts to low O2 is through Anr, a transcription factor that upregulates many genes important for microoxic and anoxic fitness.

Specifically, Anr regulates mhr which encodes a hemerythrin protein (Mhr) that binds O2 with affinities relevant to microoxia and is also necessary for full fitness of …

Development Of An Enantioselective Synthesis Of (–)-Euonyminol And Studies Towards The Total Synthesis Of (–)-Lomaiviticin A, Zhi Xu

Yale Graduate School of Arts and Sciences Dissertations

In the first chapter, I describe the development of the first enantioselective synthesis of (–)-euonyminol (1), a heavily oxidized sesquiterpenoid. Structurally, (–)-euonyminol (1) features a tricyclic framework containing an all-carbon quaternary center and nine free hydroxyl groups. Following the initial failed attempts to achieve a semi-pinacol rearrangement of an allylic silyl ether, we developed a novel oxyalkylation reaction to establish the C10 quaternary center of 1. From this intermediate, we investigated three distinct strategies to construct the tricyclic framework of 1 employing a reductive cyclization, an aldol–dehydration sequence, and a radical cyclization reaction, respectively. Finally, a series of stereoselective transformations …

Women’S Work In Film Production And The Documents Of Film History, Erin Mcguirl

Library Staff Publications

This article surfaces evidence of women’s work in film production through critical bibliographical analysis, arguing that existing textual records are robust sources for feminist film histories. Case studies covering nearly a half-century of American film history show critical bibliography in action. Treated as artifacts, documents not only exhibit women’s roles in their creation but also speak to their afterlives in the marketplace and in research libraries. Looking forward, critical bibliography can make visible below-the-line women’s labor in existing collections and inform work to curate and use new ones in the future.

Comprehensive Measurements And Analyses Of Ear Canal Geometry From Late Infancy Through Late Adulthood: Age-Related Variations And Implications For Basic Science And Audiological Measurements, Susan E. Voss, Aaron K. Remenschneider, Rebecca M. Farrar, Soomin Myoung, Nicholas J. Horton

Engineering: Faculty Publications

This study provides a comprehensive analysis of ear canal geometry from 0.7 to 91 years, based on high-resolution computed tomography scans of 221 ears. Quantified features include cross-sectional areas along the canal’s length, total canal length, curvature, and key anatomical landmarks such as the first and second bends and the cartilage-to-bone transition. Significant developmental changes occur during the first 10 years of life, with adult-like characteristics emerging between ages 10 and 15 years, likely coinciding with puberty. Substantial interindividual variability is observed across all ages, particularly in the canal area. The canal becomes fully cartilaginous at and lateral to the …