Digital Commons Network^™

The Social And Political Identities Of Latine Republicans In The U.S., Gabriella M. Mota

Dissertations and Theses

Between the 2016 and 2024 presidential elections, support for Republican candidate Donald Trump among Latine voters increased from 29% to 42%. This rise has attracted interest given Trump's nativist rhetoric and policies that target Latine immigrants. Previous literature has examined the growing Republican partisanship among Latine Americans, focusing on the processes of assimilation and the effects of racial ideology on the partisanship of the Latine electorate. Although this research is gaining traction, the political attitudes of Latine Republicans remain understudied. This study explores how Latine Republicans manipulate ethnoracial attachments to justify their support for Donald Trump and the Republican Party. …

Peer-Led Sexual And Reproductive Healtheducation Programs At Universities, Madison Michelle Patrick

Silicon Valley Sociological Review

This applied research explores the accessibility, visibility, and comprehensiveness of sexual and reproductive health (SRH) education and services at universities, with a specific focus on contraceptive risk awareness. Recognizing college students as particularly vulnerable to misinformation regarding hormonal contraceptives, unintended pregnancy, and STI exposure, the study examines the role of university-provided SRH resources in mitigating these risks.

A mixed-methods content analysis was conducted on the SRH publicly-available web pages of four Northern California universities—Stanford University, San Francisco State University, Santa Clara University, and the University of California, Berkeley, chosen for their diversity in institutional identity. The research assessed each university’s …

Association Between Area Deprivation Index And Outcomes After Subarachnoid Hemorrhage, Michelle Chung, Zhirui Deng, Dianxu Ren, Kelly Isola, Elizabeth Crago

Creating Healthy Work Environments (CHWE)

Subarachnoid hemorrhage (SAH) is a life-threatening hemorrhagic stroke caused by bleeding in the arachnoid space of the brain, often resulting in long-term disabilities and poor quality of life (QOL). Individuals living in more advantaged neighborhoods report higher levels of QOL post-stroke, but little has been reported about QOL and neighborhood data after SAH.

This study sought to examine the relationship between measures of socioeconomic status (SES) and outcomes after SAH. SES encompasses a variety of factors. For this analysis, the area deprivation index (ADI) - a measurement of neighborhood socioeconomic disadvantage - was used as a surrogate for SES. We …

Bridging The Gap Of Bipoc Patients, Clinicians, And Doulas, Tasha Chatman

Creating Healthy Work Environments (CHWE)

The project is a Doctor of Nursing practice quality improvement project addressing the barriers to collaboration between BIPOC prenatal patients, clinicians, and doulas. Maternal mortality and morbidity are a crisis in our nation with black women dying three times more than their white counterparts (Harris, n.d.). BIPOC prenatal patients are suffering from maternal mortality and morbidity. Stemming from such as historical racism, racial inequalities, implicit bias and structural determinants of health. The Doula can give cultural congruent care, impower BIPOC prenatal patients, while providing emotional and physical support. The utilization of a doula as continuous labor support is shown to …

Rna Sequencing-Based Transcriptome Analysis Of Liver In Laying Hens Supplemented With Dietary Probiotic Bacillus Species And Prebiotic Yeast (Saccharomyces Cerevisiae) Cell Walls, Ala E. Abudabos, Zafar M. Hakami, Ali R. Al Sulaiman, Riyadh S. Aljumaah, Valentino Palombo, Mashael R. Aljumaah, Mariasilvia D’Andrea, Abdulrahman S. Alharthi, Rashed A. Alhotan

Food and Animal Sciences Faculty Research

To investigate the impacts of dietary Bacillus-based probiotics and yeast-derived prebiotics on the hepatic transcriptome profile, 500 Hisex White laying hens were randomly allotted into five dietary treatments from 37 to 52 weeks of age: control; control + Bacillus subtilis; control + Bacillus subtilis and Bacillus licheniformis; control + Bacillus coagulans; and control + Saccharomyces cerevisiae yeast cell wall. Transcriptome analysis revealed a substantial number of differentially expressed genes exclusively between the control and prebiotic groups, identifying 2221 genes (FDR ≤ 0.05), with 980 genes upregulated (log2 fold change 0.69 to 24.62) and 1241 downregulated (log2 fold change −0.74 to …

Commonwealth Times 2025-08-27

Commonwealth Times, 1969-

No abstract provided.

Adapting To Southwest Idaho's Shifting Wildfire Regime: Sustainable Collaboration As A Means To Socioecological Resilience, Olivia Awbrey

Dissertations and Theses

Community wildfire adaptation is happening at multiple scales across the western United States. A range of collaboratively formed groups have addressed compounding issues related to wildfire risk, forest health and land use. In Southwestern Idaho, place-based collaboratives emerging in the early 2000s have considered trade-offs between localized social and ecological needs as they approach wildfire adaptation from the bottom-up. More recently, regional partnerships have emerged that emphasize cross-boundary wildfire risk reduction to cover larger geographic areas for risk mitigation. In between these micro- and macro-scales of activity exist bridging agencies such as county and state-level programs that account for gaps …

Class Of 2029 Officially Joins The Ole Miss Family, Marisa C. Atkinson

University of Mississippi News

OXFORD, Miss. – The Class of 2029 officially celebrated the start of their journey at the University of Mississippi during Tuesday's (Aug. 26) Fall Convocation at the Sandy and John Black Pavilion at Ole Miss.

The Illusion Of Internal Models In Biological Movement, Madhur Mangalam

Journal Articles

The concept of internal models dominates contemporary theories of sensorimotor control, with researchers across neurosciences, specifically motor control, routinely explaining observed behaviors through computational representations that supposedly exist within the nervous system. In this perspective, I present a critical examination of internal model frameworks in sensorimotor control. I argue that representational approaches mischaracterize biological systems for several fundamental reasons: (1) Internal models require homuncular interpreters, creating infinite regress problems; (2) The purported neural implementations of internal models remain empirically elusive despite decades of research; (3) Biological movement systems exhibit multiscale, nonlinear, and non-Gaussian dynamics that fundamentally defy reduction to conventional …

Lip Tie Management And Treatment, Bob Underwood, Jairrah Godsil

Pediatrics in Practice: A CME Podcast

In this episode, we’re joined by Jairrah Godsil, Occupational Therapist at Children’s Mercy, to explore the often misunderstood topic of lip ties in infants. Jairrah shares how lip ties can impact feeding, oral motor development, and long-term function—and what pediatricians should look for during early assessments. We’ll also discuss the importance of a multidisciplinary approach, the role of occupational therapy in treatment, and how to navigate the balance between anatomical structure and functional impact. Whether you’re seeing infants in your clinic or collaborating with feeding specialists, this conversation offers practical insights you won’t want to miss.

Click here to stream …

Entanglement-Assisted Metrology Under Spatiotemporally Correlated Quantum Noise, Francisco U. Riberi

Dartmouth College Ph.D Dissertations

Quantum sensors operating at the microscale are an emerging branch of quantum technologies where tangible experimental successes have already been reported. State-of-the-art atomic interferometers allow to measure and estimate a variety of physical parameters with unprecedented precision. In principle, exploiting the full power of quantum mechanics would lead to quantitatively better performance bounds over the best possible classical strategies under the same given set of resource constraints. However, the quantum systems' fragility to external disturbances has so far hindered most of these gains to be reached in practice, particularly in the limit of large probe number $N$. Parallel, {\em purely …

Optimizing Pharmacologic Treatment For Neonatal Opioid Withdrawal Syndrome (Optimize Now): A Symptom-Based Dosing Approach Study Protocol For A Multi-Center, Cluster Crossover Design Randomized Controlled Trial, Leslie W. Young, Denise C. Babineau, Abhik Das, Sara Demauro, Walter K. Kraft, Scott Lorch, Michele C. Walsh, Stephanie Merhar, Lori A. Devlin

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

BACKGROUND: Opioid use and misuse during pregnancy rose from 1.5 to 6.5 per 1000 deliveries between 1999 and 2014 and continues as a significant public health concern. A fivefold increase in neonatal opioid withdrawal syndrome (NOWS) has accompanied the increase in opioid use. The Eating, Sleeping, Consoling care approach (ESC) has been shown to improve outcomes for infants with NOWS and is quickly becoming the standard of care for infants affected by opioid use disorder. Quality improvement initiatives following the implementation of ESC provide some evidence to suggest that symptom-based (i.e., as needed, PRN, just in time) dosing of opioid …

Computational Fluid Dynamics (Cfd) Modeling For Bio-Inspired Aerodynamic Optimization In Autonomous Drones, Hyginus C.O. Unegbu, Danjuma Saleh Yawas

Makara Journal of Technology

This study explores the aerodynamic benefits of bio-inspired design modifications for autonomous drones using advanced Computational Fluid Dynamics (CFD) simulations. Four bio-inspired configurations—leading-edge serrations, winglets, riblet surfaces, and curved wings—were assessed and compared against a baseline drone model to evaluate their impact on aerodynamic performance. The results indicated that all bio-inspired designs significantly enhanced lift, reduced drag, and improved overall aerodynamic efficiency. The leading-edge serration configuration achieved the highest performance gains, with a 33.6% increase in maximum lift coefficient (CL) and a 29.5% improvement in lift-to-drag ratio (CL/CD), primarily due to delayed flow separation and reduced turbulence. Winglets minimized wingtip …

The 9th Annual Lafora Science Symposium: A Rare Epilepsy Community Makes Progress Towards Clinical Readiness, Meredith I. Williams, Katherine J. Donahue, Pascual Sanz, Souad Messahel, Jose M. Serratosa, Jordi Duran, Roberto Michelucci, Lorenzo Muccioli, Antonio Delgado-Escueta, Viet-Hong Nguyen, Berge A. Minassian, Matthew S. Gentry

Pharmacy Faculty Articles and Research

Lafora disease (LD) is a fatal childhood progressive myoclonus epilepsy and glycogen storage disease that is caused by recessive mutations in either EPM2A or EPM2B. The hallmarks of LD are cytoplasmic, aberrant glycogen-like aggregates, called Lafora bodies (LBs), that drive disease progression. The 9th Annual Lafora Science Symposium was held in San Diego, California and brought together over 70 researchers, clinicians, academic trainees, and friends and family members of patients with LD and 80 attendees joined virtually. This symposium focused primarily on international collaborations for therapeutic development and biomarker identification and strategies for preparing the Lafora community for upcoming …

Modulating Treatment Outcomes Of Patients With Solid Tumors In Immunotherapy Trials: A Drug Interaction Analysis From A Phase 1 Unit, Camila Braganca Xavier, Clark R Andersen, Joann Lim, Julian H Slade, Stacie A Bean, Lei Kang, Hung Le, Apostolia M Tsimberidou, Aung Naing, David S Hong, Ecaterina E Dumbrava, Jordi Rodon Ahnert, Paula R Pohlmann, Sarina A Piha-Paul, Stephane Champiat, Timothy A Yap, Tin-Yun Tang, Funda Meric-Bernstam, Siqing Fu

Faculty, Staff and Student Publications

Concurrent use of medications can modulate the effectiveness of immunotherapy. Although this interaction is well documented for immune checkpoint inhibitors, whether this occurs with new experimental compounds has not been evaluated. A computerized data extraction tool was used to collect clinical data and identify the prescription of a predefined set of medications within 30 days of immunotherapy infusion in the Department of Investigational Cancer Therapeutics at The University of Texas MD Anderson Cancer Center. The primary endpoints were median overall survival (OS) and progression-free survival. Tumor responses were addressed using RECIST. We identified 897 patients. The most prevalent tumor types …

Topological Indices And Quantitative Structure-Property Analysis Of Novel Drugs For Acute Lymphoblastic Leukemia Treatment, P. Nathiya, M. Suresh, Jalal Hatem Hussein Bayati

Baghdad Science Journal

Acute lymphoblastic leukemia in children is a bone marrow and blood cancer. Healthy blood cells begin to change and grow out of control when leukemia initially occurs. Acute lymphoblastic leukemia (ALL) is an immune system-related malignancy of the lymphocytes, a subtype of white blood cells. The most common form of cancer affecting children is ALL. In this work, the topological indices are derived from the structure of a chemical graph, and predict the physical, chemical, and biological characteristics of several anticancer drugs. ALL are usually treated with drugs such as methotrexate, 6-mercaptopurine (6-MP), vincristine, L-asparaginase, and/or prednisone, etc., which are …

Accurate Skin Lesion Segmentation Through Feature Fusion In Dermoscopy Images, Fallah H. Najjar, Farhan Mohamed, Asniyani Nur Haidar Abdullah, Mohd Shafry Mohd Rahim, Karrar A. Kadhim

Baghdad Science Journal

In the diagnosis of skin cancer, dermoscopy images have to be evaluated for feature extraction. In this paper, the authors design a new method to enhance the skin dermoscopy image segmentation accuracy by eliminating artifacts and hair using photometric quasi-invariants, followed by a unique approach for skin lesion segmentation using histogram-based feature fusion. Histogram features are used to extract data range and mean images from the histogram, and these are fused with the free artifacts and hair image to generate the final image. the authors used the PH2 dataset for the proposed segmentation method because it contains the ground truth …

Loss Of Dihydroceramide Desaturase Drives Neurodegeneration By Disrupting Endoplasmic Reticulum And Lipid Droplet Homeostasis In Glial Cells, Yuqing Zhu, Kevin Cho, Haluk Lacin, Yi Zhu, Jose T Dipaola, Beth A Wilson, Gary Patti, James B Skeath

2020-Current year OA Pubs

Dihydroceramide desaturases convert dihydroceramides to ceramides, the precursors of all complex sphingolipids. Reduction of DEGS1 dihydroceramide desaturase function causes pediatric neurodegenerative disorder hypomyelinating leukodystrophy-18 (HLD-18). We discovered that

Explaining Time Series Classifiers Through Post-Hoc Xai Methods Capturing Temporal Dependencies, Ephrem Tibebe Mekonnen

Conference papers

Time series classification is essential in domains such as healthcare and finance, where accurate predictions can have significant real-world consequences. However, in many high-stakes applications, understanding why a model makes a certain decision is just as important as the prediction itself. While deep learning models excel at capturing complex temporal patterns, their black-box nature limits transparency, making it difficult to trust and interpret their decisions. Although eXplainable AI (XAI) methods have advanced considerably for image and tabular data, applying them to time series remains challenging due to the intricate temporal dependencies and high dimensionality of the data. Post-hoc model-agnostic XAI …

Accelerating The Fusion Workforce In The Usa, Carlos Paz-Soldan, Eva Belonohy, Troy Carter, Laleh E. Coté, Evdokiya Kostadinova, Calvin Lowe, Subash L. Sharma, Sybil De Clark, Jaydeep Deshpande, Kate Kelly, Bobbi Makani, David A. Schaffner, Kathreen E. Thome

Faculty Research, Scholarly, and Creative Activity

The fusion energy research and development landscape has seen significant advances in recent years, with important scientific and technological breakthroughs and a rapid rise of investment in the private sector. The workforce needs of the nascent fusion industry are growing at a rate that academic workforce development programs are not currently able to match. This paper presents the findings of the Workforce Accelerator for Fusion Energy Development Conference held in Hampton, Virginia, United States of America (USA), on 29-30 May 2024, which was funded by the National Science Foundation of the USA. A major goal of the conference was to …

Heterozygous Variants In Plcg1 Affect Hearing, Vision, Cardiac, And Immune Function, Mengqi Ma, Yiming Zheng, Mingxi Deng, Shenzhao Lu, Xueyang Pan, Xi Luo, Michelle Etoundi, David Li-Kroeger, Kim C Worley, Lindsay C Burrage, Lauren S Blieden, Aimee Allworth, Wei-Liang Chen, Giuseppe Merla, Barbara Mandriani, Catherine E Otten, Pierre Blanc, Jill A Rosenfeld, Debdeep Dutta, Shinya Yamamoto, Michael F Wangler, Ian A Glass, Jingheng Chen, Elizabeth Blue, Paolo Prontera, Jeremie Rosain, Sandrine Marlin, Seema R Lalani, Hugo J Bellen, Undiagnosed Diseases Network

Duncan NRI Faculty and Staff Publications

Phospholipase C isozymes (PLCs) hydrolyze phosphatidylinositol 4,5-bisphosphate (PIP₂) into inositol 1,4,5-trisphosphate (IP₃) and diacylglycerol (DAG), important signaling molecules involved in many cellular processes including Ca²⁺ release from the endoplasmic reticulum (ER). PLCG1 encodes the PLCγ1 isozyme that is broadly expressed. Hyperactive somatic mutations of PLCG1 are observed in multiple cancers, but only one germline variant has been reported. Here, we describe seven individuals with heterozygous missense variants in PLCG1 [p.(Asp1019Gly), p.(His380Arg), p.(Asp1165Gly), and p.(Leu597Phe)] who present with hearing impairment (5/7), ocular pathology (4/7), cardiac septal defects (3/6), and various immunological issues (5/7). To model these …

A Protective Role Of Src-1 Against Aging Associated Cognitive Decline, Hesong Liu, Yongjie Yang, Jonathan C Bean, Yang He, Hailan Liu, Rambabu Majji, Chen Liang, Nan Zhang, Meng Yu, Longlong Tu, Qingzhuo Liu, Yue Deng, Kristine M Conde, Na Yin, Mengjie Wang, Yongxiang Li, Junying Han, Sanika Vattakuzhiyil Jossy, Megan Elyse Burt, Hari Krishna Yalamanchili, Chunmei Wang

Duncan NRI Faculty and Staff Publications

Introduction: Research indicates a strong correlation between obesity and the risk of dementia, both are linked to steroid receptor coactivator-1 (SRC-1), a transcriptional coactivator.

Methods: We used RNA sequencing analysis (RNA-Seq) to investigate the transcriptome of SRC-1-KO mice, and identified S100 calcium-binding protein A6 (S100A6), an AD associated gene, as one target of SRC-1. We tested cognitive behaviors in SRC-1-KO mice and mice with a humanized SRC-1 mutation (SRC-1L1376P), and performed promoter luciferase assays on S100A6.

Results: Loss of SRC-1 caused alterations in gene signatures that are commonly associated with neurodegenerative diseases, including AD, and diminished the neural plasticity of …

Nf1-Depleted Er+ Breast Cancers Are Differentially Sensitive To Cdk4/6 Inhibitors, Ze-Yi Zheng, Anran Chen, Eric J Jaehnig, Meenakshi Anurag, Jonathan T Lei, Long Feng, Chenwei Wang, Diana Fandino, Purba Singh, Hilda Kennedy, Ghazal Yadav, Craig T Vollert, Jill Tsai, Xi Chen, Yi Li, Bora Lim, Alastair Thompson, Shunqiang Li, Charles E Foulds, Bing Zhang, Matthew J Ellis, Eric C Chang

Faculty, Staff and Students Publications

Neurofibromin/NF1 is a RAS (rat sarcoma virus) GTPase activating protein and estrogen receptor (ER) transcriptional corepressor. NF1low status, identified by copy number loss or low mRNA/protein expression is associated with endocrine therapy resistance in approximately 20% of ER+/HER2− (human epidermal growth factor receptor 2) early-stage breast cancers. The identification of targeted treatments for NF1low ER+/HER2− breast cancer is therefore a priority. In this study proteogenomic analysis of ER+/HER2− breast cancer demonstrated that NF1low tumors exhibited elevated cyclin-dependent kinase 4/6 (CDK4/6) activity. In cell lines, NF1-deletion had a dual effect on CDK4 activity. First, by promoting ER recruitment to CCND1 …

The Perception Of Hooliganism And Its Impact Among Naia Collegiate Soccer Players, Eric Street, Fred Cromartie, Steve S. Chen, Brandon Spradley

Findings in Sport, Hospitality, Entertainment, and Event Management

There have been multiple studies with regard to the different aspects of soccer hooliganism throughout the world. Most commonly, studies of hooliganism covered areas such as harassment, vandalism, fighting, theft, public intoxication, and crowd disorder revolving around the games of soccer in various countries. This phenomenon has been studied among the major four professional sports in the United States, yet there has been no extensive research on soccer “hooliganism” associated with Major League Soccer (MLS). This study examined the survey responses from 101 National Association of Intercollegiate Athletics (NAIA) soccer players to identify their perceptions on severity of hooliganism and …

Antibiogram Development For Neonatal Intensive Care Unit In A Referral Hospital In Sana'a City, Yemen, Mohammed A. Kubas, Massoud K. Rassam, Amaal A. Alsayani

AUIQ Complementary Biological System

Neonates have an immature immune system, making them highly susceptible to infections. Treatment failure in newborns may result from antibiotic resistance, a significant challenge in the management of infectious illnesses worldwide. So the main objective of this research was to develop a newborn-specific antibiogram at the University of Science and Technology hospital (USTH) in Sana’a, Yemen. A retrospective analysis was conducted using microbiological data from the USTH database during the period from January 2021 to March 2022, antibiogram was generated and analyzed using the WHONET application. Gram-positive bacteria were the most frequently isolated pathogens in neonates, followed by gram-negative bacteria. …

Biosorption Of Crystal Violet Onto Fenugreek Seed Powder: Comprehensive Optimization Through Response Surface Methodology And Elucidation Of Dye Uptake Mechanism, Hasan M. Agha, Zaher Mundher Yaseen, Wafaa Raji Alfatlawi, Khansaa Al-Essa, Abdallah Reghioua, Hussein A. Kazem, Lee D. Wilson

AUIQ Complementary Biological System

This work investigates the efficacy of fenugreek seed powder (FSP), an agricultural product, as an economical and sustainable biosorbent for the extraction of crystal violet (CV) dye from aqueous environments. The biosorbent was analyzed using XRD, FTIR, and SEM-EDX, validating its amorphous structure, surface functional groups, and porous shape. Batch biosorption tests were adjusted utilizing a Box–Behnken design (BBD), incorporating three independent variables: FSP dose (0.02–0.1 g/100 mL), pH (4–10), and time (5–60 min). The model exhibited exceptional prediction accuracy (R² = 0.99, CV = 2.12%) and recognized all three variables as statistically significant (p < 0.05). The maximum CV removal attained was 91.8% efficiency at an FSP dose of 0.1 g/100 mL, pH 7, and a time of 60 minutes. FTIR examination indicated changes in the –OH, C=O, and C–O functional groups, signifying their participation in dye interaction, whilst SEM pictures validated dye deposition on the biosorbent surface. The biosorption process was ascribed to electrostatic forces, hydrogen bonding, π–π stacking, and pore filling. These findings underscore FSP as a viable, economical biosorbent for the removal of cationic dyes in wastewater treatment applications.

Mollusks From Crusader-Period ‘Akko, The Knights’ Hotel Site, Inbar Ktalav

'Atiqot

This study analyzes mollusk remains collected during the 2007 excavation season at the Knights’ Hotel site in ‘Akko, which was part of a Crusader-period residential neighborhood. A total of 538 shells were identified, including marine shells from the Mediterranean and Red Seas, freshwater shells and land snails. The analysis of these shells sheds light on the lives of the Crusader-period residents of ‘Akko, including their trade connections and use of shells for construction, ornamentation, pigment containers and raw material for the inlay industry.

Secondary Use Of Textiles For Wick Production In Light Of The Finds From The Intermediate Bronze Age Cemetery At Newe Efrayim, Naama Sukenik, Yonah Maor, Yaniv Agmon, Yossi Elisha, Gilad Itach

'Atiqot

Three Intermediate Bronze Age wicks discovered in the Newe Efrayim cemetery constitute some of the earliest known archaeological evidence of wick use, an essential object for lighting, yet lacking distinctive features, as it was intended to be burned, making it a rare find. The exceptional preservation of the wicks sheds light on both preservation issues and the technological aspects of wick production in antiquity. The wicks were made from textiles, indicating the maximal reuse of a valuable raw material after it had served its original purpose. These finds offer evidence of material recycling in the ancient world. It is likely …

Tim Burton V. Marc Ziegler

2025 Decisions

USDC for the Western District of Pennsylvania

Clss12100- The Greek And Latin Roots Of English - Syllabus, Camilo Andrés Bonilla Carvajal

Open Educational Resources

No abstract provided.