Digital Commons Network^™

The Shorthorn: October 4, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: September 30, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: September 14, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Effect Of A Multiple Intelligences Theory-Based Program On Tenth-Grade Students' Reading Comprehension Skills In Jordan, Musa Mayyas

Jordan Journal of Applied Science-Humanities Series

This study investigated the effect of a multiple intelligences theory-based program on tenth-grade students' reading comprehension skills in Jordan. The researcher used a quasi-experimental design in which the participants were divided into four groups. The participants, chosen through purposeful sampling, consisted of 110 male and female tenth-grade students from two different schools in the Ramtha Directorate of Education. The first control group consisted of 28 female students, while the first experimental group included 27 female students from the same school. The second control group comprised 24 male students, whereas the second experimental group consisted of 31 male students from the …

The Effectiveness Of The 'Hot Seat' Strategy In Teaching Arabic Grammar On Achievement According To Some Bloom's Taxonomy Levels Among Ninth-Grade Students In Jordan, Ibrahim Rababah

Jordan Journal of Applied Science-Humanities Series

This study investigated the effectiveness of the 'hot seat' strategy in teaching Arabic grammar on student achievement, according to some Bloom's Taxonomy levels. The study employed a convenience sample of 51 ninth-grade students from a selected school. The sample was divided into two groups: a control group (27 students) and an experimental group (24 students). Results indicated a positive effect of the 'hot seat' strategy on student achievement in Arabic grammar, both overall and individually, across several Bloom's Taxonomy levels.

The Level Of Emotional Balance Among Bethlehem University Students From Their Perspective, Shadia Makhlouf

Jordan Journal of Applied Science-Humanities Series

This study aimed to identify the level of emotional stability among Bethlehem University students and its relation to the following variables: gender, faculty, level of education, and place of residence. The researcher employed the descriptive research method for this study, which included 346 students randomly selected from Bethlehem University. A survey consisting of 71 statements was distributed to all 346 students. The data were analyzed using mean, standard deviation, T-test, variance analysis, and LSD test. The results indicated that the level of emotional stability among Bethlehem University students was average. Furthermore, the findings showed no correlation between emotional stability and …

About The Contributors

Impact: A Journal of Community and Cultural Inquiry in Education

No abstract provided.

Transpositions: Reflections On Friendship And Nine Days In October With Peter Beilharz And Sian Supski, Christopher G. Robbins

Impact: A Journal of Community and Cultural Inquiry in Education

In this essay, the author uses the idea of transposition to reflect on Peter Beilharz and Sian Supski's historic visit to Eastern Michigan University and southeast Michigan in October 2024. Transposition is used to deprivatize Robbins's reflections to consider broader and more generalizable concerns relative to pedagogy and educational philosophy. Further, transposition, in this regard, provided a way to reflect on the (increased) importance of friendship in academia.

Keywords: transposition, translation, friendship

Sowing The Seeds Of Utopia Collectively, From Australia To America And Everywhere In Between: A Methodology And Practice For Resistance And Emancipation, Rachelle F. Marshall

Impact: A Journal of Community and Cultural Inquiry in Education

This reflection on internationally renowned scholars Peter Beilharz and Sian Supski’s visit to Eastern Michigan University (EMU) in October 2024 presents utopia as a sociological methodology useful for research in educational studies. Presenting a brief introduction and exploration of the methodology, this article considers the cultural changes that are necessary to teach toward democratic, ecologically sustainable utopias compared to capitalist visions of utopia. As a starting point for further discussion, this personal reflection merely scratches the surface to provide a glimpse into the conditions that would underlie a democratic, ecologically sustainable utopia and serves to document a few of the …

Describing The Impact Of Nursing Courtesy And Friendliness On Patient Satisfaction, Rainavel Anadon Romano, Vimela Moodley, Jennifer De Beer, Emily Heaphy, Mohammed Qabaja, Mashael Bayazeed, Ilona Novotna, Elaine Quadra, Maab Basha, Rehab Alassiri

Creating Healthy Work Environments (CHWE)

INTRODUCTION: Patient satisfaction in healthcare is significantly influenced by nurse-patient interactions, where attributes like friendliness, courtesy, and effective communication play crucial roles. This study aims to identify specific components of these attributes that enhance patient satisfaction, providing insights for targeted interventions, such as communication training, to improve nurse-patient interactions and overall patient-centered care.

BACKGROUND: Patient satisfaction reflects how content patients feel with the care they receive, aligning their preferences and expectations with the healthcare provided. Nurses, who are pivotal in patient care, can greatly influence this experience. The friendliness and courtesy displayed by nurses not only foster trust but create …

The New Modifications To The Diagnostic Criteria For Autism Spectrum Disorder In Dsm-5 And Their Impact On The Field Of Autism Spectrum Disorder, Imam Al-Qazzaz

Jordan Journal of Applied Science-Humanities Series

This study aimed to highlight the modifications that affected the diagnosis of Autism Spectrum Disorder (ASD) in the Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM-5), published by the American Psychiatric Association (APA) in May 2013. These modifications impacted many aspects related to the disorder, such as the creation of Autism Spectrum Disorder (ASD) as a separate category that represents a spectrum of symptoms, replacing the category of Pervasive Developmental Disorders (PDDs) that included Autistic Disorder and other disorders according to DSM-IV-TR. Additionally, the revisions involved the integration, development, and deletion of certain diagnostic criteria related to …

Publication Citations (Calendar Year 2024), Valparaiso University

Valparaiso Scholarship and Creative Works Reception

No abstract provided.

Strategies To Improve Project Portfolio Management In The Pharmaceutical Industry, Emely Nhi Thi Ai Nguyen

Walden Dissertations and Doctoral Studies

Poor management of pharmaceutical project portfolios can negatively impact a pharmaceutical company’s product development and profitability. Project portfolio managers must ensure the successful development of new products in the pharmaceutical pipeline as the financial investment in new product development is significant and if not managed effectively can negatively impact profitability and prevent launch of new treatment therapies. Grounded in the project portfolio management framework, the purpose of this qualitative pragmatic inquiry study was to explore successful project portfolio management (PPM) strategies that drug project portfolio managers use to contribute to business success. The participants were six employees that managed portfolios …

Abundance And Demography Of The Wood Turtle (Glyptemys Insculpta) Across Two River Systems In Michigan’S Lower Peninsula, Marianne Kelso

Masters Theses

Turtles worldwide are declining from habitat loss and fragmentation, predation, and illegal collection, and their slow life histories and sensitivity to environmental change make reliable abundance and demographic data critical for conservation. Wood turtles (Glyptemys insculpta) are declining across much of their range, yet baseline information is lacking in Michigan’s Lower Peninsula. To fill that gap, we performed standardized visual mark–recapture surveys at 27 one-kilometer river reaches in two distinct watershed systems during springs of 2022 and 2023. Using hierarchical N-mixture models with negative binomial mixtures to account for imperfect detection, we estimated site-level latent abundance and evaluated …

Dna Double-Stranded Breaks, A Hallmark Of Aging, Defined At The Nucleotide Resolution, Are Increased And Associated With Transcription In The Cardiac Myocytes In Lmna-Cardiomyopathy, Benjamin Cathcart, Sirisha M Cheedipudi, Leila Rouhi, Zhongming Zhao, Priyatansh Gurha, Ali J Marian

Faculty, Staff and Student Publications

Aims: An intrinsic feature of gene transcription is the formation of DNA superhelices near the transcription bubble, which are resolved upon induction of transient double-stranded breaks (DSBs) by topoisomerases. Unrepaired DSBs are pathogenic as they lead to cell cycle arrest, senescence, inflammation, and organ dysfunction. We posit that DSBs would be more prevalent at the genomic sites that are associated with gene expression. The objectives were to identify and characterize genome-wide DSBs at the nucleotide resolution and determine the association of DSBs with transcription in cardiac myocytes.

Methods and results: We identified the genome-wide DSBs in ∼1 million cardiac myocytes …

Hiv-1 Controllers Possess A Unique Cd8+ T Cell Activation Phenotype And Loss Of Control Is Associated With Increased Expression Of Exhaustion Markers, Amber D. Jones, Zachary Capriotti, Erin Santos, Angel Lin, Rachel Van Duyne, Stephen Smith, Zachary Klase

Kimmel Cancer Center Papers, Presentations, and Grand Rounds

BACKGROUND: HIV-1 controllers are a rare population of individuals that exhibit spontaneous control of HIV-1 infection without antiretroviral therapy. Understanding the mechanisms by which HIV-1 controllers maintain and eventually lose this ability would be highly valuable in HIV-1 cure or vaccine research. Previous work revealed the ability of CD8+ T cells isolated from HIV-1 controllers to suppress HIV-1 replication in matched CD4+ T cells and PBMCs ex vivo and suggested the loss of control may be tied to CD8+ T cell exhaustion.

RESULTS: We explored whether CD8+ T cell exhaustion plays a role in the maintenance and loss of control …

Peptide-Based Inorganic Nanoparticles As Efficient Intracellular Delivery Systems, Amir Nasrolahi Shirazi, Rajesh Vadlapatla, Ajoy Koomer, Anthony Nguyen, Vian Khoury, Keykavous Parang

Pharmacy Faculty Articles and Research

Background/Objectives: Peptide-based inorganic nanoparticles (PINPs) have emerged as promising candidates for intracellular delivery due to their unique structural and functional attributes. These hybrid nanostructures combine the high surface area and tunable optical/magnetic properties of metal cores (e.g., Au, Ag, Fe3O4) with the biocompatibility, targeting specificity, and responsive behavior of peptides. In particular, peptides with amphipathic or cell-penetrating features could facilitate efficient transport of molecular cargos across cellular membranes while enabling stimulus-responsive drug release in target tissues. Methods: We review key synthesis methods (especially green, peptide-mediated one-pot approaches), functionalization strategies (e.g., thiol-gold bonds, click chemistries), and characterization techniques (TEM, …

Ole Miss Student Combines Passions In Italian Medical Fellowship, Marisa C. Atkinson

University of Mississippi News

OXFORD, Miss. – Sparked by a love of travel and aspirations of becoming a doctor, University of Mississippi junior Samantha Ragan experienced the best of both worlds when she spent time in Italy this summer as part of a global health fellowship program.

Ruth Gatrell, Myrna J. Layton

Faculty Publications

Ruth Josephine Barton was born on December 23, 1921, in Farmington, Utah. Her parents were Lloyd and Edna (Cottrell) Barton. When the Bartons married, Edna already had a five-year-old daughter, Helen, from a previous marriage. Ruth was the first of two children born to Edna’s second marriage. The family was living in Mount Pleasant, Utah, but returned to the home of Edna’s father, Edward Cottrell, for the birth of the baby. She was named Ruth for the biblical heroine, and Josephine because she shared a birthday with the prophet Joseph Smith. A younger sister, Laura Jean, joined the family in …

Geol 64: Planetary Geology - Syllabus, Dara Laczniak

Open Educational Resources

This Open Educational Resources (OER) syllabus is for an introductory planetary geology course that utilizes results from space missions to expose students to the surface features, composition, geological activity, and probable history of the planets, moons, asteroids, and comets of the solar system. It also places space exploration into the context of larger societal issues such as global warming and natural resource availability and addresses topics such as the ethics of space exploration and hazards of space travel. This OER syllabus aims to foster student-centered learning, critical thinking, data analysis and communication skills, and creativity. Assigned readings are compiled into …

Editorial: Endocrine Imbalances Of Mineral Ions And Vitamins In Chronic Disease Pathogenesis, Mor-Li Hartman, Hosam G. Abdelhady, Mohammed S. Razzaque

School of Medicine Publications

No abstract provided.

An Antioxidant Approach To Ameliorate The Effects Of Radiation And Chemotherapy On Cognition, Raymond Anan Otoo

Theses and Dissertations

Acute Lymphoblastic Leukemia (ALL) is a hematologic malignancy that primarily affects children and young adults. While advancements in treatment—including chemotherapy and cranial irradiation—have significantly improved 5-year survival rates in children to nearly 90%, radiation-induced cognitive impairment (RICI) remains a persistent and debilitating side effect. The brain, particularly the hippocampus, is highly susceptible to radiation-induced oxidative stress and inflammation. In the treatment of ALL, the combined use of chemotherapy and radiotherapy contributes to a heightened oxidative burden, exacerbating the risk of cognitive dysfunction. Although previous studies have linked radiation exposure to neurocognitive decline, the molecular mechanisms underlying RICI and chemotherapy-induced cognitive …

Comprehending Students' Experiences With A Language Learning Resource Center: A Descriptive Phenomenological Study Of College Life And Belonging, Paulina Dzieza

Dissertations

This study explores the impact of Language Learning Resource Center (LLRC) services on college students' overall college experience and their sense of belonging on campus. In the constantly evolving world of higher education, higher education institutions work to provide welcoming spaces where students can flourish academically and socially. In higher education, where there is a growing focus on student support services, the LLRC is essential for promoting academic achievement, cross-cultural interaction, and social integration for foreign language learners. This qualitative study, guided by a combined theoretical framework of Community of Practice and Ethics of Care, aims to advance knowledge of …

The Immunophenotypic And Genetic Characterization Of Pediatric T -L Ymphoblastic Leukemia With A Mature Immunophenotype, Mahsa Khanlari, Wei Wang, Parastou Tizro, Mohammad K Eldomery

Faculty, Staff and Student Publications

Not available.

August 28, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Bi-5756 Reduces Graft-Versus-Host Disease Through Cb1-Mediated Treg Upregulation, Sena Kim, Abdul-Jalil Dania, Sora Lim, Jaebok Choi

2020-Current year OA Pubs

Cannabinoid receptor 1 (CB1) has been implicated in multiple inflammatory diseases by regulating pro-inflammatory mediators or altering immune cell polarization. However, the expression and direct functional role of CB1 in T cells remain largely unexplored. Here, we demonstrate that primary murine T cells express CB1 and that its novel agonist, BI-5756, directly increases the frequencies of regulatory T cells (Tregs) in primary murine pan T cells after activation. In addition, BI-5756 exhibits an in vivo protective effect against graft-versus-host disease (GvHD), an allogeneic T cell-mediated inflammatory complication after allogeneic hematopoietic cell transplantation (allo-HCT), resulting in an improved overall survival with …

Alterations In Ether Lipid Metabolism In Obesity Revealed By Systems Genomics Of Multi-Omics Datasets, Yvette Schooneveldt, Sudip Paul, Kevin Huynh, Habtamu B. Beyene, Natalie A. Mellett, Gerald F. Watts, Joseph Hung, Jennie Hui, John Beilby, John Blangero

Human Genetics Publications

Ratios between two metabolites are sensitive indicators of metabolic changes. Lipidomic profiling studies have revealed that plasma ether lipids, a class of glycero- and glycerophospho-lipids with reported health benefits, are negatively associated with obesity. Here, we utilized lipid ratios as surrogate markers of lipid metabolism to explore the processes underlying the inverse relationship between ether lipid metabolism and obesity. Plasma lipidomics data from two independent human cohorts (n = 10,339 and n = 4,492) were integrated to assess the associations between 82 lipid ratios and obesity-related markers in males and females. Results were externally validated using mouse transcriptomics data …

Evolving Paradigms In Acute Myeloid Leukemia: Personalized Approaches To Therapy Across Age And Risk Groups, Sumeet Yadav, Utsav Joshi, Guleid Hussein, Mohamed Warsame, Bolun Liu, Abhash Shrestha, Peter Krastev, Hariprasad Reddy Korsapati, Amrit Singh

Student Publications

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by the clonal proliferation of myeloid precursors and rapid progression. Historically consisting of intensive chemotherapy, AML management has evolved significantly due to advances in molecular diagnostics and risk stratification. This review discusses current therapeutic paradigms in AML, emphasizing the growing role of personalized medicine across age and risk groups. For younger, fit patients, intensive regimens such as the "7 + 3" protocol remain the standard, often enhanced by targeted agents like FMS-like tyrosine kinase 3 (FLT3) and IDH inhibitors. Older or unfit individuals benefit from low-intensity treatments such as hypomethylating …

Pressure And Force Dynamics In Artificial Muscle Actuators: A State-Space And Optimization-Based Approach, Mohammad Elzein

Dissertations and Theses

This two-part investigation explores the dynamic behavior of braided pneumatic actuators (BPAs) under bio-inspired pulse modulation, with the aim of improving their biomimetic force output and control. The first study examines the effect of pulse length and inter-pulse timing on BPA performance, revealing that force output is highly sensitive to the temporal structure of input pulses mirroring biological muscle behavior. Using dual-pulse actuation schemes, the results demonstrate that force responses exceed the additive contributions of individual pulses, with peak amplification occurring consistently at a 27 ms inter-pulse gap. Shorter pulse lengths (10–20 ms) yielded the highest normalized force increases, up …

C-C Motif Chemokine Receptor-Like 2 Promotes The Interferon-Γ Signaling Response In Myeloid Neoplasms With Erythroid Differentiation And Mutated Tp53, Nour Sabiha Naji, Sergiu Pasca, Theodora Chatzilygeroudi, Pablo Toledano-Sanz, Joseph Rimando, Yuju An, Yashvi Hemani, Brandy Perkins, Xinghan Zeng, Conover Talbot, Bogdan Paun, Abdulmuez Abdulmalik, Chen Lossos, Tatianna R Boronina, Ilias Sinanidis, Panagiotis Tsakiroglou, Priyanka Fernandes, Christopher Esteb, Alexander J Ambinder, Robert N Cole, Rena Xian, Ivana Gojo, Suman Paul, Mark J Levis, Amy E Dezern, Leo Luznik, Styliani Karanika, Linda S Resar, Richard J Jones, Frederick Bunz, Lukasz Gondek, Marios Arvanitis, Theodoros Karantanos

Faculty, Staff and Students Publications

Patients with myeloid neoplasms with loss-of-function TP53 mutations and erythroid differentiation have poor outcomes, and a better understanding of disease biology is required. Upregulation of interferon-γ (IFN-γ) signaling has been associated with acute myeloid leukemia (AML) progression, selection of TP53 mutated clones and chemotherapy resistance, but its drivers remain unclear. In this study, we found that the surface receptor C-C motif chemokine receptor-like 2 (CCRL2) is overexpressed in AML with erythroid differentiation and TP53 mutations compared to other AML subtypes and healthy hematopoietic cells. CCRL2 knockout (KO) suppressed erythroleukemia growth in vitro and in vivo. Further proteomics and transcriptomics analysis …