Digital Commons Network^™

Stem Integration In The Classroom: An Exploratory Case-Study On Teachers Defining Their Stem Identity And Role As A Stem Educator, Tawana Guillaume

Theses and Dissertations

The push for inclusion of science, technology, engineering, and mathematics (STEM) as a meta-discipline in K-12 education is recognition that the challenges faced by society require technology skills, interdisciplinary problem-solving, and an increased number of people entering STEM professions (Dare et al., 2014; English, 2016; Fan et al., 2021; Holstein & Keene, 2013; Roehrig et al., 2012, 2021; Sanders, 2008). The dissertation in practice explored STEM teacher identity and conceptions of STEM as a function of STEM professional experience outside of the field of education. The exploratory casestudy sought to identify the relationship between STEM career-based experiences – specifically the …

Improved Extraction And Detection Of Disinfection Byproducts, Impacts Of Wildland-Urban Interface Wildfires On Drinking Water, And Change In Disinfection Byproducts Over Time In Chlorinated Vs. Chloraminated Distribution Systems, Patrick Thomas Justen

Theses and Dissertations

Drinking water disinfection is critical to prevent the occurrence of waterborne pathogens in drinking water. However, disinfection causes the unintended formation of disinfection byproducts (DBPs) through the reaction of disinfectants (e.g., chlorine, chloramine) with natural organic matter (NOM), algal matter, or anthropogenic pollutants present in source waters. Exposure to DBPs is associated with increased bladder cancer, colorectal cancer, miscarriage, and birth defects. The U.S. EPA currently regulates eleven DBPs in drinking water—four trihalomethanes, five haloacetic acids, bromate, and chlorite. However, research shows that DBP related toxicity in drinking water is driven mainly by other, non-regulated DBPs, particularly iodinated DBPs and …

Inspiring Girls To Fill The Blank Space In Stem: The Impact Of An After-School Coding And Robotics Club On Elementary Female Students' Engagement And Self-Efficacy In Computer Science, Lisa Guenther Wilbanks

Theses and Dissertations

The purpose of this action research was to describe how participation in an after-school coding and robotics program influenced elementary female students’ engagement and self-efficacy in computer science. According to a 2023 report from the National Science Foundation, in 2020 women earned only 21% of computer science degrees and 24% of engineering undergraduate degrees in the United States. As two of the fastest growing fields, the lack of female perspectives and experiences will continue to limit innovation in these areas. Studies show that gender gaps in engagement and self-efficacy in STEM begin long before students enter college and the workforce, …

Adipokines Mediate Fat-To-Ovary Communication To Regulate Oogenesis, Adipocyte Size, And Lipid Storage In Drosophila Melanogaster, Chad Herbert Simmons

Theses and Dissertations

Humans have complex signaling pathways that allow them to store and expend energy based on nutritional quality and availability. Inter-organ signaling is used to communicate nutrient availability between organs based on nutritional needs and the rate of cellular division. Our main overarching question is to investigate how fat-derived signals affect adipocyte morphology and the maintenance of stem cells in the ovary. While signaling pathways, like insulin and mTOR, and some adipokines that are involved in inter-organ nutrient sensing have been identified, the exact nutrient reliant mechanisms of stem cell maintenance are not completely understood. Using Drosophila melanogaster as a model, …

Ai-Driven Autonomous Manufacturing: A Novel Taxonomy, Vision-Guided Planning, And Diversity-Aware Active Learning Frameworks, Ibrahim Yousif

Theses and Dissertations

Manufacturers face two opposing challenges: the escalating demand for customized products and the pressure to reduce lead times. Current manufacturing equipment, although reliable, operates at the limits of its technology and lacks adaptability to dynamic environments. This trade-off has been described as the optimal degree of automation, a threshold beyond which further automation incurs more cost than benefit. Smart manufacturing has introduced adaptive, data-driven systems, but many deployments still lack the contextual adaptability and autonomous decision-making required to handle unplanned disruptions. This underscores the need for intelligent, autonomous systems capable of real-time adaptation without costly reconfiguration, minimizing human intervention during …

Self-Defense Without Overreach: How Status Of Forces Agreements Address The Legal Gaps In Article 51, Alexis Shaw

Vanderbilt Journal of Transnational Law

No abstract provided.

Decorin Evokes A Pro-Lysosomal Pathway In Lymphatic Endothelial Cells, Gabriel J. Pascal, Dipon K. Mondal, Sadie Kim, Christopher Xie, Devanarayanan Siva Sankar, Jörn Dengjel, Renato V. Iozzo

Kimmel Cancer Center Faculty Papers

The lymphatic system is critical to the body's immune and circulatory system, and lymphangiogenesis, the development of new lymphatic vessels from pre-existing ones is a significant process capitalized upon by cancer during tumorigenesis. Decorin is a small leucine-rich proteoglycan which we have previously shown to be anti-tumorigenic and a suppressor of lymphangiogenesis. We have also shown that decorin exercises its anticancer properties through its ability to evoke autophagy. Through a comprehensive and unbiased proteomic analysis, we explored the implications of decorin exposure on protein expression within mouse lymphatic endothelial cells. We discovered that decorin enriches several protein pathways, notably proteasomal …

Exploring Insect-Based Tourism Potential In Mount Makiling Forest Reserve Through Tourism Insights, Alexis John T. Fajardo, Rogelio T. Andrada Ii, Roberto G. Visco, Dianne Joy D. Aguilon

Journal Article

This study explored the potential of offering insect-based tourism in the Mount Makiling Forest Reserve (MMFR) to diversify its ecotourism portfolio and reinforce promotion of biodiversity conservation. Addressing a global lack of research that explores insect-based tourism, this study analyzed the perceptions, experiences, attitudes, knowledge, and interests of 584 tourists regarding their motivation and possible participation in such an activity. The findings revealed strong tourist interest, with 73.3% expressing a desire to engage in insect-based tourism and 67.5% specifically stating they would participate if the activity were offered at MMFR. Although 29.8% of tourists were unfamiliar with the concept of …

The Association Between Inflammatory Bowel Disease And Ischemic Heart Disease: A Retrospective Cohort Study, Mahmoud H. Mosli, Dima M. Alsulami, Yara K. Alghamdi, Abdullah S. Badahdah, Asmaa H. Alhibshi, Thamer M. Alamri, Maan S. Alkhattabi, Khames T. Alzahrani, Hadeel A. Alsufyani, Omar I. Saadah

Saudi Medical Journal

ABSTRACT Objectives: To evaluate the association between Inflammatory bowel disease (IBD) and Ischemic heart disease (IHD). Methods: A retrospective cohort analysis included patients with and without IBD seen at the outpatient gastroenterology clinic of a large tertiary care hospital between January 2015 and October 2022. The primary outcome was the association between IBD and IHD, and the secondary outcome was predictors of IHD in patients with IBD. Results: The study included 400 patients; 291 were IBD patients, and 109 had other non-inflammatory GI disorders. The IBD group displayed significantly lower rates of hyperlipidemia (8.6% vs. 30.3%, p <0.001), diabetes mellitus (DM) (10% vs. 24.8%, p <0.001), and hypertension (11.7% vs. 32.1%, p <0.001) compared to the non-IBD group. Only 2.7% (n=8) of IBD patients developed IHD. Logistic regression analysis did not demonstrate a significant association between IBD and IHD ( p =0.932). Among classical risk factors, only hypertension (OR: 26.2, 95% CI: 2.14–661, p =0.016) and hyperlipidemia (OR: 10.5, 95% CI: 1.32–132, p =0.0405) significantly increased the risk of developing IHD among patients with IBD. Conclusion: In this cohort, there is no increased risk of developing IHD in patients with IBD compared to non-IBD patients.

An Evaluation Of Pharmaceutical Clinical Trials From Saudi Arabia Registered On Clinicaltrials.Gov: A Cross-Sectional Study, Mohammad H Aljawadi, Khalid F. Alonazi, Ibrahim M. Alsultan, Nora A Kalagi, Marwan A. Alrasheed, Abdullah M. Alhammad

Saudi Medical Journal

ABSTRACT Objectives: To evaluate clinical trials involving pharmaceutical agents conducted in Saudi Arabia and registered on ClinicalTrials.gov. Since the early 2000s, Saudi Arabia has expanded its involvement in clinical research. Recognizing the importance of clinical trials, we aimed to analyze the clinical trial landscape in the Kingdom to identify well-covered areas and potential gaps. Methods: In this descriptive cross-sectional study, ClinicalTrials.gov was used as the primary source to collect data regarding pharmacological and biological interventions conducted in Saudi Arabia between 2002 and June 2025. Results: A total of 474 pharmaceutical studies were included. Of these, 52.95% were completed, indicating moderate …

Molecular Identification Of Respiratory Syncytial Virus, Seasonal Influenza Viruses, And Sars-Cov-2 In Respiratory Tract Infections: A Cross-Sectional Study In Taif City, Mazen M. Almehmadi, Faiha A Alharbi, Ahmad K. Shawush, Mamdouh A. Allahyani, Osama A. Abdulaziz, Ayman S. Alhazmi, Ahmad A. Aghamdi

Saudi Medical Journal

ABSTRACT Objectives: To explore the prevalence of respiratory tract infections (RTIs) in Taif via molecular diagnosis method, to enhance the clinical decision making and the need for vaccination strategies. Methods: A 5864 participants were enrolled in this study, all from Taif city. Samples were collected via nasal swab, throat swab, or sputum sample. The duration of the study were 24 months from January 2023 to December 2024. Samples were transported in viral transport medium. Then processed using GeneXpert system. Fluorescent probes detected viral RNA and reported as detected or not detected. Chi-square test was applied for statistical analysis purposes. Results: …

Mama, Appa, And Titi: What Makes Words Sound Parental? A Phonological Exploration Of Parental Terms In And Beyond The Gender Binary, Madeleine C. S. Kruckemeye , '26

Senior Theses, Projects, and Awards

This paper addresses the following research question: What phonological components make a word sound ‘parental’ cross-linguistically and (how) do those components relate to the social genders associated with the word? The goal in answering this question is to extend Jakobson (1960) and Murdock’s (1959) work to be inclusive of our current understanding of gender and gender roles, and to create more options for queer parents and other families that are recognizable as parental terms, an important factor as found by Frank et al. (2017). The research consists of a literature review, an analysis of cross-linguistic parental terms, and an online …

Characterization Of The Fatigue Threshold Behavior Of Uhmwpe, Bethany B. Smith, Anurag Roy, Robert O. Ritchie, Lisa A. Pruitt

Faculty Journal Articles

Ultra-high-molecular-weight-polyethylene (UHMWPE) has been the material of choice for bearings in total joint replacements (TJRs) for decades as a result of its excellent wear resistance, chemical inertness, energetic toughness, low friction, and biocompatibility. Utilization of this polymer in orthopedic devices requires oxidation, wear, and fatigue resistance. Balancing these important properties by tailoring processing techniques and modulating microstructural features has been an ongoing endeavor in the field. Research into the clinical applications of UHMWPE has primarily focused on the challenges of wear and oxidation while studies into the realm of fatigue have been more limited. Literature gaps exist in fully understanding …

We Are Missing Multiple Model Integration In The Psychology Of Implicit Bias, Nathan Lackey

Philosophy

Since the 1990s, psychologists have developed multiple models of prejudicial attitudes. I argue that these models generally fall into one of two categories: individualistic or situationist. The former abstract away (or omit) environmental features from the system of interest and locate the phenomenon in the mind of the individual. However, new models of prejudicial attitudes have foregrounded just those features abstracted away in preceding models. These conceptualizations of attitudes foreground situations. The scientists that posit them claim that measures of implicit bias are better understood as measures of places as opposed to people, for example. These categories of models have …

Association Between Suboptimal Health Status And Academic Performance: A Cross-Sectional Study Of 1,028 Medical Students In Punjab, Pakistan, Maleha Asim, Misbah Malik, Aneela Jamil, Raheela Yasmin, Ghazala Jawwad, Wajahat Ullah Khan

Indonesian Journal of Research in Physical Education, Sport, and Health

Background: Suboptimal health status (SHS) refers to the transitional period between health and illness, characterized by unexplained symptoms and premature changes in functional status without a known medical diagnosis. Objective: The aim is to examine how often SHS occurs and how lifestyle factors influence both SHS and the academic success of medical students. Methods: A Cross-sectional survey was conducted from February 2024 to September 2024 with first- to fifth-year medical students from four randomly chosen medical colleges in Punjab, Pakistan. The Suboptimal Health Measurement Scale (SHMS V1.0), Pittsburgh Sleep Quality Index (PSQI), and Health-Promoting Lifestyle Scale (HPLS) were used to …

Building Access To Care For Women And Girls+ With Bleeding Disorders: The Wgbd Clinic Of Excellence Model, Ming Y. Lim, Katherine C. Anguiano, Shannon L. Carpenter, Kerry B. Funkhouser

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

The Brain-Derived Neurotrophic Factor (Bdnf) And Its Importance To Organism Survival And Development, Christopher Monnett Smith

Holster Scholar Projects

Brain-Derived Neurotrophic Factor (BDNF) has been the subject of numerous studies regarding the functioning of the brain in relation to topics such as neural plasticity and neural survival. However, BDNF has also been implicated in the induction of changes not only in neural tissue but multiple other tissue types across the human body. The aim of this literature review is to provide a comprehensive, yet brief, overview of BDNF’s influence on the functioning of the nervous, cardiovascular, respiratory, muscular, and immune systems.

Lost In Translation: Chomskyan Analysis Of Language Variation In Ai, Post-Critical Learners, And Native Speakers, Hannah Van Rijnswou

Holster Scholar Projects

Artificial Intelligence (AI) and Large Language Models (LLMs) have revolutionized linguistic theory, raising questions about human language acquisition. Some argue AI's language generation challenges the concept of innate linguistic ability, while others contend it reinforces it. This research examines AI's "Surplus of the Stimulus" learning—relying on vast datasets—against human language acquisition, particularly within Chomskyan frameworks of Universal Grammar and the "Poverty of the Stimulus." By analyzing language production across three groups—Native English Speakers, Post-Critical Period Second Language Learners, and LLMs—this study compares linguistic complexity using the Lexical Opulence Index (LOI). Data is collected through structured prompts across four linguistic registers: …

Climate Change And Human Migration, Jennifer R. Guzmán

Climate Change and the Individual, 2025-26

Migration is one of the oldest human behaviors and among the most important of human survival strategies. Climate change has always been a significant driver of human migration because humans are interdependent with the ecosystems where they live. Today’s climate change is anthropogenic, and its harmful effects are made worse by social inequities. Millions are having to leave their homes, including internally displaced people, climate refugees, and labor migrants. Radical changes are needed in science, policy, law, and cultural narratives to minimize the harms of climate displacement.

All-Cause And Cause-Specific Mortality Among Patients With Narcolepsy., Chih-Wei Hsu, Yen-Shan Yang, Yang-Chieh Brian Chen, Liang-Jen Wang, Mu-Hong Chen, Yao-Hsu Yang, Chih-Sung Liang, Edward Chia-Cheng Lai

Children’s Nutrition Research Center Staff Publications

Importance: Narcolepsy is a sleep disorder potentially affecting mortality, yet evidence on this association remains sparse.

Objective: To examine whether narcolepsy is associated with an increased risk of all-cause and cause-specific mortality.

Design, setting, and participants: This retrospective cohort study used data from the Taiwan National Health Insurance Research Database (NHIRD) from 2001 to 2021, with patients followed up until death or December 31, 2022. Patients were aged 6 years or older with 2 or more narcolepsy diagnoses from psychiatrists or neurologists. Controls were selected from the NHIRD as a population-based sample. Controls without narcolepsy were matched in a 1:4 …

Investigating The Presence Of R-Loops At The Centromeres Of Drosophila Melanogaster, Daniel D'Souza

Holster Scholar Projects

This study investigates the presence and localization of R-loops at the centromeres of Drosophila melanogaster. R-loops are non-canonical nucleic acid structures that have been implicated in various cellular processes, including genomic instability and accurate chromosome segregation. Although previous research has found R-loops at Drosophila satellite sequences and LTR retrotransposons, their presence and function at the centromeres of a whole organism remain largely unknown. Using IF-FISH (immunofluorescence-fluorescence in situ hybridization), we stained R-loops with the S9.6 antibody. A UAS-rnh1 overexpression line was used to induce the overexpression of RNase H1, an enzyme that resolves R-loops, to confirm the specificity of …

Targeting Rna With Small Molecules Using State-Of-The-Art Methods Provides Highly Predictive Affinities Of Riboswitch Inhibitors, Narjes Ansari, Chengwen Liu, Florent Hédin, Jérôme Hénin, Jay W Ponder, Pengyu Ren, Jean-Philip Piquemal, Louis Lagardère, Krystel El Hage

2020-Current year OA Pubs

Targeting RNA with small molecules represents a promising yet relatively unexplored avenue for the design of new drugs. Nevertheless, challenges arise from the lack of computational models and techniques able to accurately model RNA systems, and predict their binding affinities to small molecules. Here, we tackle these difficulties by developing a tailored state-of-the-art approach for absolute binding free energy calculations of RNA-binding small molecules. For this, we combine the advanced AMOEBA polarizable force field to the newly developed lambda-Adaptive Biasing Force scheme associated to refined restraints allowing for efficient sampling. To capture the free energy barrier associated to challenging RNA …

Distinct Roles For B Cell-Derived Ltα3 And Ltα1Β2 In Tnf-Mediated Ileitis, Emma C Erlich, Quazim A Alayo, Ayoung Kim, Jichang Han, Rachel L Mintz, Christopher G Huckstep, Heather S Ruiz, Rachael L Field, Taylor J Dunning, Leila S Saleh, Mark H Hoofnagle, Farshid Guilak, Jonathan R Brestoff, Rafael S Czepielewski, Gwendalyn J Randolph, Et Al.

2020-Current year OA Pubs

Crohn's disease pathology is modeled in TNF

The Not-So-Silent Side Effects Of Upzoning: Noise Pollution, Mackenzi Barrett

Vanderbilt Law Review

A broad coalition has formed to oppose restrictive zoning laws. According to this coalition, zoning is largely to blame for the current housing crisis facing the United States, and to increase the housing supply, cities across the country should embrace upzoning—that is, loosen zoning laws to allow for greater density. Like many other well-intentioned policy changes, upzoning has the possibility for negative unintended consequences. Among those consequences is noise pollution. In recent decades, noise pollution has gone largely undiscussed in the United States. Notwithstanding this neglect, existing research demonstrates that noise pollution can have serious adverse effects on people’s health …

Physicochemical And Structural Optimization Of Date (Phoenix Dactylifera L.) Syrup: Impact Of Extraction Temperatures And Pectin Addition, Afna Thaivalappil Abdul Asiz

Theses

This thesis focuses on the optimization of date (Phoenix dactylifera L.) syrup, an emerging natural sweetener rich in glucose, fructose, and bioactive compounds, by investigating how extraction temperature and pectin incorporation influence its physicochemical and structural properties. Therefore, the main objective of this study was to examine how extraction temperatures (25°C, 50°C, 75°C, and 90°C), and the incorporation of lowmethoxyl pectin (LMP, DE 31%) and high-methoxyl pectin (HMP, DE 85%) prior to concentration, affect the quality, stability, and functionality of date syrup. The results showed that increasing extraction temperatures increased the total soluble solids (16 °Brix at 25°C to …

Advances In Iot, Ai, And Sensor‑Based Technologies For Disease Treatment, Health Promotion, Successful Ageing, And Ageing Well, Yuzhou Qian, Keng Siau

Research Collection School Of Computing and Information Systems

Recent advancements in the Internet of Things (IoT) and artificial intelligence (AI) are unlocking transformative opportunities across society. One of the most critical challenges addressed by these technologies is the ageing population, which presents mounting concerns for healthcare systems and quality of life worldwide. By supporting continuous monitoring, personal care, and data-driven decision-making, IoT and AI are shifting healthcare delivery from a reactive approach to a proactive one. This paper presents a comprehensive overview of IoT-based systems with a particular focus on the Internet of Healthcare Things (IoHT) and their integration with AI, referred to as the Artificial Intelligence of …

Morphology-Aware Hrv Estimation From Wrist Ppg In Sedentary Scenarios, Changshuo Hu, Hung Manh Pham, Dong Ma

Research Collection School Of Computing and Information Systems

Photoplethysmography (PPG) is widely used in wearable devices for non-invasive heart rate variability (HRV) monitoring. While most prior work focuses on mitigating motion artifacts, recent studies highlight that even subtle contact pressure variations can distort waveform morphology and lead to inaccurate HRV estimates. In this work, we propose a morphology-aware deep learning framework that conditions HRV estimation on beat-level waveform types. Our model jointly encodes the raw PPG waveform and a sequence of pressure-induced morphology labels using parallel encoders, integrates them via cross-attention, and predicts normal-to-normal (NN) intervals and beat count to support downstream HRV computation. Evaluated on the public …

Does Increasing Canopy Liana Density Decrease The Tropical Forest Carbon Sink?, Stefan A. Schnitzer, David M. Defilippis

Biological Sciences Faculty Research and Publications

The ongoing decline in the American tropical forest carbon sink has serious ramifications for atmospheric carbon levels and global climate change. Increasing liana abundance may explain the decaying carbon sink because lianas reduce canopy tree growth and survival, which limits forest carbon storage. However, canopy lianas, not solely understory lianas, would have to be increasing for this hypothesis to be credible because canopy lianas compete especially intensely with canopy trees. We examined the change in canopy lianas over 10 years on Barro Colorado Island (BCI), Panama to test two main hypotheses. (1) Canopy lianas are increasing on BCI. (2) Increasing …

Enhancing Llm Code Generation: A Systematic Evaluation Of Multi-Agent Collaboration And Runtime Debugging For Improving Accuracy, Reliability, And Latency, Nazmus Ashrafi

Theses

The use of large language models (LLMs) for automated code generation has emerged as a significant focus within AI research. As these pretrained models continue to evolve, their ability to understand and generate complex code structures has opened up new possibilities for automating intricate programming tasks with greater accuracy. Although contemporary foundational models demonstrate promising results, researchers continue to explore optimal post-training strategies to enhance code quality. These include supervised fine-tuning, retrieval-augmented generation (RAG), debugging, and many others. In this thesis, I combine two such widely used post training approaches—namely (1) multi agent collaboration and (2) runtime execution of information-based …

Analyzing Sea Level Rise Scenarios Impact On The Mobility, Infrastructures, Environment Of Abu Dhabi And Defining Solutions By Creating A Digital Twin Using Gis And Game Engine, Justine Sylviane Lucie Sarrau

Dissertations

This dissertation investigates the potential impact of future sea level rise (SLR) scenarios on the city of Abu Dhabi. With climate change, many coastal towns are at risk of experiencing this type of natural hazard. Currently, no precise scenario simulations have been developed, mainly due to the use of low spatial resolution elevation data. Additionally, the difficulty in understanding the real impacts persists when analyses rely solely on traditional cartography and GIS methods. This dissertation aims to advance the field by offering a new approach, which involves creating a comprehensive dynamic 3D simulation with dynamic flowing water. This model, defined …