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2025

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"I'Ve Never Felt A Pain Like This" A Dialogic Analysis Of Parent-Child Estrangement Narratives On Reddit, Grant W. Lane Jan 2025

"I'Ve Never Felt A Pain Like This" A Dialogic Analysis Of Parent-Child Estrangement Narratives On Reddit, Grant W. Lane

Graduate Student Theses, Dissertations, & Professional Papers

How do adult children estranged from their parent(s) create meaning and make sense of their estrangement in Reddit posts on the subreddit r/EstrangedAdultChild? This study analyzed Reddit posts written by estranged adult children for a presumed audience of other estranged adult children. Using relational dialectics theory (RDT) as a lens for analysis, this research examined the competing discourses that influence the meaning-making and sense-making processes of estranged adult children in their posts when the intended audience is fellow estranged adult children. Seventy-four posts from r/EstrangedAdultChild, authored by adult children who self-identified as estranged from at least one parent, were collected …


Trace Level Benzoylecgonine Detections In Equine Plasma/Serum – A Proposed Interim Plasma Level Regulatory “Cut-Off“, Andreas F. Lehner, Kimberly Brewer, Levent Dirikolu, Abelardo Morales Briceñod, Robert Holland, George Maylin, Clara Fenger, Thomas Tobin Jan 2025

Trace Level Benzoylecgonine Detections In Equine Plasma/Serum – A Proposed Interim Plasma Level Regulatory “Cut-Off“, Andreas F. Lehner, Kimberly Brewer, Levent Dirikolu, Abelardo Morales Briceñod, Robert Holland, George Maylin, Clara Fenger, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Cocaine is a widely used human recreational substance routinely transferring at pharmacologically irrelevant trace level amounts to non-user humans and horses. Horses and humans rapidly demethylate cocaine to benzoylecgonine which is excreted in urine at concentrations approaching two thousand times higher than the corresponding plasma cocaine concentrations. In human workplace drug testing, these usually pharmacologically irrelevant trace level urinary detections of benzoylecgonine are handled by application of a 100 ng/ml urinary “cut-off“, as presented by the Substance Abuse and Mental Health Services Administration (SAMHSA). In horse racing several American states have long used published urinary “cut-offs“ for benzoylecgonine of from …


Risk And Prognosis Of Hepatocellular Carcinoma In Mexican Americans With Type 2 Diabetes Mellitus, Rikita I Hatia, Lu-Yu Hwang, Ruosha Li, Catherine Troisi, Prasun K Jalal, Christopher I Amos, Henry F Gomez, Yun Shin Chun, Asif Rashid, Ahmed O Kaseb, Paul A Scheet, Manal M Hassan Jan 2025

Risk And Prognosis Of Hepatocellular Carcinoma In Mexican Americans With Type 2 Diabetes Mellitus, Rikita I Hatia, Lu-Yu Hwang, Ruosha Li, Catherine Troisi, Prasun K Jalal, Christopher I Amos, Henry F Gomez, Yun Shin Chun, Asif Rashid, Ahmed O Kaseb, Paul A Scheet, Manal M Hassan

Faculty, Staff and Student Publications

INTRODUCTION: Hepatocellular carcinoma (HCC) disproportionately affects Hispanic persons with higher age-specific incidence and increased mortality rates compared to non-Hispanic Whites. These high rates of incidence and mortality may be explained by the variation in risk factors. Given the high prevalence of type 2 diabetes mellitus (DM) among the Hispanic population, we aimed to assess the risk and prognosis of HCC in Mexican Americans with type 2 DM with consideration of treatment for DM.

METHODS: A case-control study of 241 Mexican American HCC patients and 500 healthy controls in Texas was conducted. Multivariable logistic regression analysis was performed to determine the …


Intercellular Mitochondrial Transfer Contributes To Microenvironmental Redirection Of Cancer Cell Fate, Julie Sofie Bjerring, Yara Khodour, Emilee Anne Peterson, Patrick Christian Sachs, Robert David Bruno Jan 2025

Intercellular Mitochondrial Transfer Contributes To Microenvironmental Redirection Of Cancer Cell Fate, Julie Sofie Bjerring, Yara Khodour, Emilee Anne Peterson, Patrick Christian Sachs, Robert David Bruno

School of Medical Diagnostics & Translational Sciences Publications

The mammary microenvironment has been shown to suppress tumor progression by redirecting cancer cells to adopt a normal mammary epithelial progenitor fate in vivo. However, the mechanism(s) by which this alteration occurs has yet to be defined. Here, we test the hypothesis that mitochondrial transfer from normal mammary epithelial cells to breast cancer cells plays a role in this redirection process. We evaluate mitochondrial transfer in 2D and 3D organoids using our unique 3D bioprinting system to produce chimeric organoids containing normal and cancer cells. We demonstrate that breast cancer tumoroid growth is hindered following interaction with mammary epithelial cells …


Secondhand Tobacco Smoke Exposure And Sleep Disturbance In School-Aged Children In Appalachian Ohio, Ketrell Mcwhorter, Christine Kim, Timothy J. Hilbert, Danielle E. Mcbride, Anthony A. Mangino, Patrick J. Parsons, Kurunthachalam Kannan, Erin N. Haynes Jan 2025

Secondhand Tobacco Smoke Exposure And Sleep Disturbance In School-Aged Children In Appalachian Ohio, Ketrell Mcwhorter, Christine Kim, Timothy J. Hilbert, Danielle E. Mcbride, Anthony A. Mangino, Patrick J. Parsons, Kurunthachalam Kannan, Erin N. Haynes

Epidemiology and Environmental Health Faculty Publications

Introduction: Secondhand tobacco smoke (SHS) exposure remains a major public health concern for children and has been implicated in sleep disturbances through biological and behavioral mechanisms. Different methods of measuring SHS exposure have yielded inconsistent results. This study examined the relationship between SHS exposure and sleep among rural Appalachian 7–9-year-olds, utilizing three SHS measurements: natural log-transformed (ln) serum cotinine concentrations, dichotomized serum cotinine levels (≥0.05 vs. <0.05 ng/ml), and parent/caregiver report of ≥1 smoker in the home. We hypothesized SHS-exposed children would have a significantly higher prevalence of sleep disturbance—e.g., short sleep, frequent snoring, night awakenings—compared to unexposed, regardless of measurement method. Methods: We used data from the Marietta Community Actively Researching Exposure Study, a cohort of 404 children in Marietta and Cambridge, Ohio. Sleep disturbances were parent/caregiver-reported. Linear models were used for continuous outcomes to estimate beta coefficients; log-binomial models with generalized estimating equations (exchangeable correlation) were applied for dichotomized outcomes to estimate prevalence ratios (PR), each with 95% confidence intervals (CI). Results: Twenty-six percent of children had a parent/caregiver report of ≥1 sleep disturbance. There was a 35% increased prevalence of short sleep [PR = 1.35 (95%CI:1.02–1.80), p =.04] with each unit increase of ln serum cotinine levels, adjusting for age, sex, parent education, BMI percentile, and history of breathing difficulties in the past two years. Increasing ln serum cotinine levels were associated with a significant 5.5-min decrease in average sleep duration in age-adjusted models. Conclusions: Higher SHS exposure was associated with poorer sleep outcomes, with serum cotinine emerging as the only measure linked to short sleep, underscoring the importance of smoke-free environments, particularly in rural communities, and objective exposure assessment.


Oral Anticoagulation In The Era Of Continuous Rhythm Monitoring, Chu-Pak Lau, Hung-Fat Tse Jan 2025

Oral Anticoagulation In The Era Of Continuous Rhythm Monitoring, Chu-Pak Lau, Hung-Fat Tse

Journal of the Hong Kong College of Cardiology

Background

Primary prevention of stroke using oral anticoagulants (OACs) is indicated for clinical atrial fibrillation (AF) documented on standard electrocardiogram (ECG) in those patients with a high risk of stroke. The recent availability of both external ECG monitors (either using consumer electronic or medical devices) and implantable devices have enabled earlier AF episodes to be detected before clinical AF become manifest. These episodes, often termed subclinical AF (SCAF), represent an area of controversy for the application of OAC.

Objective

The present review summarises the management of SCAF, based on recent guidelines and publications in the following areas:

  1. In the presence …


Academic Stress, Performance, And Satisfaction Among Undergraduate Nursing Students Under The Semester System, Kalyani Sinha, Sangeetha Priyadarshini, Baby S Nayak, Meghna Pandit Jan 2025

Academic Stress, Performance, And Satisfaction Among Undergraduate Nursing Students Under The Semester System, Kalyani Sinha, Sangeetha Priyadarshini, Baby S Nayak, Meghna Pandit

Manipal Journal of Nursing and Health Sciences

Introduction: Stress is a key indicator of psychological well being. Various factors contribute to the psychological disturbances among undergraduate students. These issues can affect academic satisfaction and increase stress. Examination-related stress negatively impacts students’ academic performance. Each course determines its assessment methods, content, learning strategies and instructional approaches. Objectives: This study assessed academic stress, performance, and satisfaction among undergraduate nursing students in the semester system at selected nursing colleges in Udupi District, Karnataka and find it’s relationship. Method: A descriptive study was conducted among 210 undergraduate students selected from the second and fourth semesters using a purposive sampling …


An Investigation Of Maritime Piracy And Its Implications To The Development And Sustainability Of The Port Harcourt Seaport, Its Local Communities And The Niger Delta Region In Nigeria., Nsikan Umoette Jan 2025

An Investigation Of Maritime Piracy And Its Implications To The Development And Sustainability Of The Port Harcourt Seaport, Its Local Communities And The Niger Delta Region In Nigeria., Nsikan Umoette

Plymouth Business School Theses

ABSTRACTWithin the last decade, widespread ramifications of maritime piracy occasioned by insurmountable piratical attacks in the Gulf of Guinea region have been evidently seen in the Nigerian territorial waters with hallmarks on strategic areas in the Niger Delta region, Nigeria – the Port Harcourt seaport, its local communities, and the Niger Delta region. It is against this backdrop that this study investigates maritime piracy and its implications for the development and sustainability of the Port Harcourt Seaport, its local communities, and the Niger Delta region in Nigeria. Incorporating maritime piracy and sustainability in the literature review showed the social and …


Finite Element Modeling For Two-Dimensional Wireless Capsule Endoscope Manipulation System, Wael S. Abbas, Mohamed T. El-Wakad, R.R. Darwish Jan 2025

Finite Element Modeling For Two-Dimensional Wireless Capsule Endoscope Manipulation System, Wael S. Abbas, Mohamed T. El-Wakad, R.R. Darwish

Trends in advanced sciences and technology

The inadequacies of traditional flexible endoscopes used in gastrointestinal diagnostic procedures, causing pain and discomfort to patients, led to the development of the wireless capsule endoscope. There are two types of wireless capsule endoscopes: passive and active. The passive wireless capsule endoscope cannot stop at a specific position for diagnostic purposes, which can lead to capsule retention. The active capsule can solve those problems. In this article, we use COMSOL Multiphysics to simulate a two-dimensional (2D) electromagnetic actuation (EMA) system for active wireless capsule endoscope. The EMA system uses a stationary two-pair coil system (Helmholtz and Maxwell). The capsule endoscope …


The Possible Protective Effect Of Coenzyme Q10 And Indole-3-Carbinol On Cyclosporine Induced Nephrotoxicity In Rats, Maha A. Ollaek, Gehan S. Georgy, Engy M. El Morsy, Eman M. Raafat Jan 2025

The Possible Protective Effect Of Coenzyme Q10 And Indole-3-Carbinol On Cyclosporine Induced Nephrotoxicity In Rats, Maha A. Ollaek, Gehan S. Georgy, Engy M. El Morsy, Eman M. Raafat

Trends in advanced sciences and technology

Background: Cyclosporine A (CsA) is a potent immunosuppressive drug, with nephrotoxicity being its most frequent adverse effect, primarily due to the involvement of free radicals in inflammatory and fibrotic pathways. Both coenzyme Q10 (CoQ10), a fat-soluble vitamin-like molecule, and indole-3-carbinol (I3C), a natural compound, possess anti-inflammatory and antioxidant properties. Aim: This study aimed to investigate the potential protective effects of CoQ10 and/or I3C against CsA-induced nephrotoxicity in rats. Methods: Male albino rats were randomly assigned to five groups, with six rats in each group. Group (1) served as the normal control group and received corn oil orally by gavage for …


Repair And Regeneration Of Low Dose Ionizing Radiation To Injured Muscles Using Barium Chloride In A Rat Model, Esraa A. Aboelfadl, Hesham Haffez, Soheir S. Koraa, Ahmed E. Abdel Moneim, Ola H. El-Habit, Rasha S. Elbeltagy Jan 2025

Repair And Regeneration Of Low Dose Ionizing Radiation To Injured Muscles Using Barium Chloride In A Rat Model, Esraa A. Aboelfadl, Hesham Haffez, Soheir S. Koraa, Ahmed E. Abdel Moneim, Ola H. El-Habit, Rasha S. Elbeltagy

Trends in advanced sciences and technology

The biological consequences of low dose ionizing radiation (LDIR) are strongly debated. While most studies confirm its detrimental effects, several studies suggest beneficial (hormetic) effects of LDIR as an anti-inflammatory agent on musculoskeletal injuries. The present study aimed to investigate the bio-stimulatory effects of LDIR (direct and indirect) in healing the musculoskeletal injuries induced by barium chloride (BaCl2). Thirty adult male Albino rats were used in this study and were divided into five groups as follows: control, BaCl2, g-rays (direct), g-rays (indirect), BaCl2 and g (direct), and BaCl2 and g (indirect) group. Muscle injury was induced using 50 ml of …


Adme Predicted Molecular Intervention Aiming At Assessment Of An Alternative Means Of Phyto-Based Pest Control Of Cotton Leaf Roller, Haritalodes Derogata Using Diluted Ethanolic Extract Of Nux Vomica, Arnob Chakrovorty, Avidipta Hazra, Banani Bhattacharjee, Debarsi Das, Anisur Rahman Khuda-Bukhsh, Asmita Samadder Jan 2025

Adme Predicted Molecular Intervention Aiming At Assessment Of An Alternative Means Of Phyto-Based Pest Control Of Cotton Leaf Roller, Haritalodes Derogata Using Diluted Ethanolic Extract Of Nux Vomica, Arnob Chakrovorty, Avidipta Hazra, Banani Bhattacharjee, Debarsi Das, Anisur Rahman Khuda-Bukhsh, Asmita Samadder

Trends in advanced sciences and technology

The leaf roller moth, Haritalodes (=Sylepta) derogata (Fabricius, 1775) (Lepidoptera) is a common pest of many economically important plant species including cotton (Gossypium spp.) and okra (Abelmoschus esculentus). This study was designed to investigate mainly the insecticidal/pesticidal efficacy of diluted ethanolic extract from seeds of native deciduous Indian tree, Strychnos nux-vomica Linn. (Nux Vom 2X - prepared by diluting raw extract or mother tincture 100 times in 91% ethanol by following homeopathic procedure) known to contain the main toxic ingredient, Strychnine and to elucidate the toxicity related cellular and physio-chemical effects inflicted by it on larva of H. derogata. Present …


To Explore Potential Targets And Their Natural Inhibitors To Combat Diabetes, Rishita Dey, Sisir Nandi, Asmita Samadder Jan 2025

To Explore Potential Targets And Their Natural Inhibitors To Combat Diabetes, Rishita Dey, Sisir Nandi, Asmita Samadder

Trends in advanced sciences and technology

Diabetes is a chronic metabolic disorder that affects millions of people around the globe. Prolonged hyperglycemia, abnormal metabolism of fats and carbohydrates, oxidative damage, and a high incidence of microvascular diseases are the common hallmarks of diabetes and its complications. This condition has been shown to hasten the onset of several other disorders, including peripheral neuropathy, nephropathy, and cardiomyopathy, pulmonary arterial disease, and coronary artery disease, thereby necessitating exploration of different avenues of medicinal regimen to address / delineate the complications. The subject matter for this review has been gathered from a range of research publications, review papers, and book …


Complex Plant Disease Syndromes Induced By Plant Parasitic Nematodes And Phytopathogenic Bacteria: Interactions, Mechanisms And Management, Atef M. El-Sagheer, Eman A. Hammad, Radwa G. Mostafa Jan 2025

Complex Plant Disease Syndromes Induced By Plant Parasitic Nematodes And Phytopathogenic Bacteria: Interactions, Mechanisms And Management, Atef M. El-Sagheer, Eman A. Hammad, Radwa G. Mostafa

Trends in advanced sciences and technology

Plant-parasitic nematodes (PPNs) are among the most significant agents contributing to plant disease complexes, acting both as direct parasites and as facilitators of bacterial infections. Their interactions with phytopathogenic bacteria are multifaceted, involving mechanical wounding caused by stylet penetration, disruption of plant cell integrity, and alteration of host physiology. These changes create favourable conditions for bacterial entry, colonization, and systemic spread. Additionally, PPNs can suppress plant defines responses and modify root exudate profiles, thereby enhancing bacterial survival and virulence in the rhizosphere. Such interactions often lead to a synergistic increase in disease incidence and severity, resulting in greater yield losses …


Genetic Mutations Affecting Dentin Formation: Molecular Insights And Therapeutic Strategies, Mohamed Yehia Abdelfattah, Yara Sameh Said, Shimaa A. Elsaady, Shahenda A. Abdallahahmed, Wael Abou-Zeid Jan 2025

Genetic Mutations Affecting Dentin Formation: Molecular Insights And Therapeutic Strategies, Mohamed Yehia Abdelfattah, Yara Sameh Said, Shimaa A. Elsaady, Shahenda A. Abdallahahmed, Wael Abou-Zeid

Trends in advanced sciences and technology

Writing a comprehensive review on gene mutations affecting dentin mineralization requires thorough research and organization, as each section examines how specific mutations influence this process, supported by relevant findings. Mutations in genes such as DSPP, DMP1, andMEPE impair dentin structure and mineralization by disrupting odontoblast function, dentin matrix integrity, and mineral deposition. These genetic alterations interfere with key biological processes, including odontoblast differentiation and matrix formation, through altered signaling pathways such as Wnt/β- catenin and TGF-β, contributing to dental disorders like Dentinogenesis Imperfecta (DI). Gaining molecular insights into these disruptions enhances our understanding of dentin biology and supports early diagnosis, …


Supporting Second-Year College Students In The Murky Middle, Alisha L. Kimble Jan 2025

Supporting Second-Year College Students In The Murky Middle, Alisha L. Kimble

University of the Pacific Theses and Dissertations

This study articulates the needs and expectations of an intersectional population of undergraduate college students: second-year students in the murky middle. Nearly half of all student dropouts occur after the first year of enrollment, with more than 45% occurring by mid-performing students. Despite this, institutions, like researchers, do not readily focus on the retention of this population of students; a Noel Levitz study (2013) found a disparity in the prevalence of retention practices for first-year students (94%-98%) and second-year students (20%-29%). This general qualitative study utilized a semi-structured interview protocol with nine participants to gather information about the participants’ needs …


The Development Of A Children’S Book Designed To Use Bibliotherapy And Mindfulness Skills To Promote Interoception In Young Children With Insecure Attachment As A Result Of Adverse Childhood Experiences, Zenaida Agramonte Jan 2025

The Development Of A Children’S Book Designed To Use Bibliotherapy And Mindfulness Skills To Promote Interoception In Young Children With Insecure Attachment As A Result Of Adverse Childhood Experiences, Zenaida Agramonte

University of the Pacific Theses and Dissertations

One third of children in the United States have experienced trauma known in the literature as Adverse Childhood Experiences (ACEs). The long-term outcomes of ACEs have a higher likelihood of reducing interoceptive awareness—the ability to sense internal body signals like heart rate, hunger, pain, and emotions. Research suggests that interventions, such as mindfulness and attachment therapies are useful for increasing interoceptive awareness, regulating emotions, and fostering secure attachment in adults. However, apart from attachment, interventions are lacking for young children. Bibliotherapy is one such intervention designed for young children which potentially fosters secure attachment between child and adult storytellers and …


Unrestrained Voices: A Qualitative Thematic Analysis On Formerly Incarcerated Trans People’S Perceptions Of Safety During Incarceration, James Anthoney Crawford Jan 2025

Unrestrained Voices: A Qualitative Thematic Analysis On Formerly Incarcerated Trans People’S Perceptions Of Safety During Incarceration, James Anthoney Crawford

Theses and Dissertations

Heightened risks of violence, discrimination, and insufficient institutional protections mark the experiences of incarcerated trans individuals. This qualitative thematic analysis investigated the perceptions of safety among formerly incarcerated trans people within U.S. correctional facilities. Using qualitative research methods, the study gathered firsthand accounts of physical and sexual assault, examined institutional responses to reported incidents, and assessed the effectiveness of the Prison Rape Elimination Act of 2003 in addressing the unique vulnerabilities of trans inmates. Data collection involved oral history transcript analysis, which was analyzed through thematic coding to identify patterns of institutional neglect, inadequate training of correctional staff, and systemic …


Evaluation Of The Maneuverability Of An 85m Fishing Trawler (Focusing On Dynamic Stability), Chun-Ki Lee, Su-Hyung Kim Jan 2025

Evaluation Of The Maneuverability Of An 85m Fishing Trawler (Focusing On Dynamic Stability), Chun-Ki Lee, Su-Hyung Kim

Journal of Marine Science and Technology–Taiwan

Most fishing vessels are less than 100 meters in length, so IMO maneuverability standards do not apply. As a result, studies on the maneuverability of fishing vessels are considerably fewer compared to those on merchant ships. However, with technological advancements, the size of fishing vessels continues to grow, and as more fishermen are on board, accidents could lead to fatal casualties. In response, the authors determined that research on the maneuverability of fishing vessels is urgently needed. Thus, the authors conducted a maneuverability evaluation on a fisheries training vessel with the hull shape of a fishing trawler, 85 meters in …


A Hybrid Image Filtering Approach For Improving Edge Detection Of Riverbed Particles With Complex Textures, Po-Wei Lin, Hsun-Chuan Chan Jan 2025

A Hybrid Image Filtering Approach For Improving Edge Detection Of Riverbed Particles With Complex Textures, Po-Wei Lin, Hsun-Chuan Chan

Journal of Marine Science and Technology–Taiwan

The distribution of particle size in gravel-bed rivers affects the flow condition, sediment transport, and river morphology. However, conventional particle size analysis is laborious and time-consuming. To enhance the efficiency of particle size analysis, image-based methods have been widely explored, but complex particle textures increase the difficulty in identifying particle edges during image analysis. This study develops a filtering approach based on the rolling guidance filter and leverages the differences in grayscale gradients between particle edges and textures to design a guidance image tailored for the rolling guidance filter. This design enables the filter to preserve particle edges while smoothing …


Comparison Of Canopy Materials To Improve The Performance Of Sea Anchors Used For Fishing Operations, Namgu Kim, Su-Hyung Kim, Yoo-Won Lee, Kyung-Jin Ryu Jan 2025

Comparison Of Canopy Materials To Improve The Performance Of Sea Anchors Used For Fishing Operations, Namgu Kim, Su-Hyung Kim, Yoo-Won Lee, Kyung-Jin Ryu

Journal of Marine Science and Technology–Taiwan

Sea anchors used for fishing operations help improve catch rates by stabilizing vessel drift speeds to match tidal or ocean currents. The underwater resistance experienced by a sea anchor's canopy significantly impacts its performance, yet there has been limited research on canopy materials. This study investigates how different canopy materials can enhance sea anchor performance. Specifically, we tested sea anchors made from three fabrics: the currently used polyamide (PA) material, PA material with increased yarn density in the weft direction, and polyester (PES). Using Korean national standards, we compared the yarn density, weight, water absorption capacity, drying rate, air permeability, …


Research On Ship Track Prediction Based On Ipso-Cnn, Xiangen Bai, Nuo Chen, Xiaofeng Xu Jan 2025

Research On Ship Track Prediction Based On Ipso-Cnn, Xiangen Bai, Nuo Chen, Xiaofeng Xu

Journal of Marine Science and Technology–Taiwan

With the rapid development of the global economy, international imports and exports have become increasingly important. Timely and effective tracking and prediction of ship trajectories are important in the face of complex maritime traffic. Based on AIS data, this study establishes a ship trajectory prediction model combining improved particle swarm optimization (IPSO) and a convolutional neural network (CNN) that uses the ship's historical navigation trajectory data to predict the future navigation trajectory. The historical ship trajectory data of the Port of Ningbo-Zhoushan were selected for the experiment, and the IPSO-CNN model experiment results were compared with those of other models. …


Using Secreted Biomarkers In The Development Of The Detection Of Advanced Cancer Screening System, Elaine Vanterpool Jan 2025

Using Secreted Biomarkers In The Development Of The Detection Of Advanced Cancer Screening System, Elaine Vanterpool

Student Posters

An estimated 20 million people globally develop cancer every year. Furthermore, over 9.7 million people die from cancer. The best prognosis of cancer occurs when detected early. Cancer, in its early stages, usually does not display clinical symptoms and is usually not detectable by symptoms and is diagnosed later. The goal of the D.A.C.S. is to provide a screen that can detect cancer. It is hypothesized that developing a cancer detection system/technology, named D.A.C.S. (Detection of Advanced Cancer Screening) system, can help with early cancer detection, while still being affordable for the general public.


Mutation In Rpl10 Disrupts Ribosomal Function And Contributes To Autism Spectrum Disorder, Elaine Vanterpool, Paula Ramirez-Mejia Jan 2025

Mutation In Rpl10 Disrupts Ribosomal Function And Contributes To Autism Spectrum Disorder, Elaine Vanterpool, Paula Ramirez-Mejia

Student Posters

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by difficulties in social communication and restricted, repetitive behaviors, interests, or activities. A study in 2020 estimated that ASD affects 2.8% of children in the United States (NIMH). The RPL10 gene, encodes the Ribosomal protein L10, has been implicated in ASD and plays a crucial role in protein synthesis and neuronal development, contributing to a protein essential for assembling the large ribosomal subunit. This study investigates how variations in PRL10 (Ribosomal Protein L10) can contribute to ASD.


Eed Gene Variants And Irritable Bowel Syndrome: A Genetic Approach To Understanding Ibs, Elaine Vanterpool, Ted Howard Jan 2025

Eed Gene Variants And Irritable Bowel Syndrome: A Genetic Approach To Understanding Ibs, Elaine Vanterpool, Ted Howard

Student Posters

Irritable Bowel Syndrome is a disease linked with the gastrointestinal system and seen to cause bloating, abdominal pain, and harmful alterations in the digestive system. Its cause is complex and is known to have both environmental and genetic factors. Recent studies have shown that IBS occurs due to genetic variations, which leads to the pathogenesis of IBS. One gene, the EED (Embryonic Ectoderm Development) gene has been involved in various biological processes, particularly gastrointestinal functions. The purpose of this study is to explore the potential relationship between the EED gene and IBS.


Analyzing The Inhibition Of Chemical Compounds On Collagenase In P. Aeruginosa, Elaine Vanterpool, Marielle Cooper, Kiara Cameron Jan 2025

Analyzing The Inhibition Of Chemical Compounds On Collagenase In P. Aeruginosa, Elaine Vanterpool, Marielle Cooper, Kiara Cameron

Student Posters

Pseudomonas aeruginosa is an opportunistic pathogen that poses significant challenges in clinical treatment due to its production of collagenase. This bacterium can cause several infections including pneumonia, meningitis, septicemia, and a host of other diseases. Collagenase acts as a key virulence factor by breaking down collagen in the host’s extracellular matrix, allowing bacteria to invade tissues. This study hypothesized that the effects of cell secreted collagenase would be inhibited by metronidazole, vanillin, and silver nanoparticles to reduce the pathogenicity of Ps. aeruginosa related infections.


Analysis Of Cys294arg Mutation In Cs1 Associated With Periodontal Ehlers-Danlos Syndrome & Collagen Degradation, Elaine Vanterpool, Amy Aboki Jan 2025

Analysis Of Cys294arg Mutation In Cs1 Associated With Periodontal Ehlers-Danlos Syndrome & Collagen Degradation, Elaine Vanterpool, Amy Aboki

Student Posters

C1s enzyme plays a crucial role in the immune system so that the body can fight infection and repair damaged tissues. However, if it is not working properly, it will do more harm than good. This is shown in the case of periodontal Ehlers-Danlos syndrome (pEDS), a rare genetic disorder whereby C1s breaks down collagen I, a protein that gives structure and strength to connective tissues. Severe gum disease, loose teeth and premature teeth is a result of this. The purpose of this study is to identify and analyze the pathogenicity of C1s mutations and association in pEDS.


Impact Of Feeding Different Fat Sources And Levels Of Vitamin E Isoforms To Heavy Slaughter Weight (150 Kg) Pigs: Ii. Belly And Bacon Quality, Marlee Kelley, Ding Wang, Ana Paula A.A. Salim, Merlin D. Lindemann, Gregg Rentfrow, Surendranath P. Suman Jan 2025

Impact Of Feeding Different Fat Sources And Levels Of Vitamin E Isoforms To Heavy Slaughter Weight (150 Kg) Pigs: Ii. Belly And Bacon Quality, Marlee Kelley, Ding Wang, Ana Paula A.A. Salim, Merlin D. Lindemann, Gregg Rentfrow, Surendranath P. Suman

Animal and Food Sciences Faculty Publications

Two independent experiments were performed to evaluate the effect of dietary fat sources and vitamin E supplementation on the characteristics of belly and bacon from heavy slaughter weights (150 kg) pigs. In experiment 1, 64 individually fed pigs (32 barrows and 32 gilts) were randomly assigned to 1 of the 8 dietary treatments in a 4 × 2 factorial arrangement. Four fat sources included cornstarch (CS), tallow (TW), corn oil (CO), and coconut oil (CN). Vitamin E supplementation included alpha-tocopheryl acetate (ATA) at 11 and 200 ppm. In experiment 2, individually fed pigs (n = 72; 36 barrows, 36 gilts) …


Impact Of Feeding Different Fat Sources And Levels Of Vitamin E Isoforms To Heavy Slaughter Weight (150 Kg) Pigs: I. Carcass Characteristics And Fresh Pork Quality, Marlee Kelley, Ding Wang, Gregg Rentfrow, Merlin D. Lindemann, Ana Paula A.A. Salim, Surendranath P. Suman Jan 2025

Impact Of Feeding Different Fat Sources And Levels Of Vitamin E Isoforms To Heavy Slaughter Weight (150 Kg) Pigs: I. Carcass Characteristics And Fresh Pork Quality, Marlee Kelley, Ding Wang, Gregg Rentfrow, Merlin D. Lindemann, Ana Paula A.A. Salim, Surendranath P. Suman

Animal and Food Sciences Faculty Publications

The objective of this study was to evaluate the effect of supplementing α-tocopheryl-acetate (ATA) and γ-tocopherol (GT) vitamin E isoforms with corn oil (CO) and tallow (TW) on carcass characteristics and meat quality characteristics of pigs grown to heavy weights (150 kg). Individually fed pigs (n = 72; 36 barrows, 36 gilts) were randomly assigned to 12 dietary treatments in a 2 × 6 factorial arrangement. Fat treatments were 5% TW and 5% CO. The vitamin E treatments included 4 levels of ATA (11, 40, 100, and 200 ppm) and 2 levels of mixed tocopherols (primarily GT; 40 and 100 …


Wet Aging For 21 Days Improves Tenderness Of Beef Biceps Femoris Muscle Without Affecting Color Stability, Ana Paula A.A. Salim, Mahesh N. Nair, Yifei Wang, Anna C.V.C.S. Canto, Gregg Rentfrow, Surendranath P. Suman Jan 2025

Wet Aging For 21 Days Improves Tenderness Of Beef Biceps Femoris Muscle Without Affecting Color Stability, Ana Paula A.A. Salim, Mahesh N. Nair, Yifei Wang, Anna C.V.C.S. Canto, Gregg Rentfrow, Surendranath P. Suman

Animal and Food Sciences Faculty Publications

Beef whole-muscle cuts containing biceps femoris (BF) exhibit inferior tenderness compared to cuts from the ribs and loins. The BF is a sizeable muscle in beef round, and enhancing tenderness of BF may increase the value of beef carcasses. While wet aging for 21 d improves beef tenderness, it can compromise color. Therefore, we evaluated the effects of wet aging on color and tenderness of beef BF to identify an optimal aging duration for these quality traits. The BF muscles were collected 24 h postmortem from 8 beef carcasses (n = 8), divided into equal sections, vacuum packaged, and aged …