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Articles 24211 - 24240 of 31522
Full-Text Articles in Entire DC Network
Integrated System Of Swarm Intelligence And Neural Network For Molecular Similarity Detection, Fadia Sami, Hakan Koyuncu
Integrated System Of Swarm Intelligence And Neural Network For Molecular Similarity Detection, Fadia Sami, Hakan Koyuncu
Baghdad Science Journal
Molecular similarity, governed by the principle that "similar molecules exhibit similar properties," is a pervasive concept in chemistry with profound implications, notably in pharmaceutical research where it informs structure-activity relationships. This study focuses on the pivotal role of molecular similarity techniques in identifying sample molecules akin to a target molecule while differing in key features. Within the realm of artificial intelligence, this paper introduces a novel hybrid system merging Swarm Intelligence (SI) behaviors (Aquila and Termites) with Neural Networks. Unlike previous applications where Aquila or Termites were used individually, this amalgamation represents a pioneering approach. The objective is to determine …
A New Algorithm For Finding The Roots Of Nonlinear Algebraic Equations, Ahmad Yousef Alrazzo, Nasr Al Din Ide, Mohammad Assaad
A New Algorithm For Finding The Roots Of Nonlinear Algebraic Equations, Ahmad Yousef Alrazzo, Nasr Al Din Ide, Mohammad Assaad
Baghdad Science Journal
In this paper, the algorithm (Stochastic Gradient Descent) SGD, which is one of the most famous optimization algorithms, was hybridized with genetic algorithms in finding the roots of non-linear equations, which is one of the most important mathematical problems due to its application in all sciences. Genetic algorithms are used here to find the optimal primary root of SGD algorithm and its application in reducing the studied objective function. Some famous algorithms need initial point to reach the solution in terms of stability. The proposed algorithm is tested on several standard functions and the results are compared with the famous …
Topological Indices And Qspr/Qsar Analysis Of Some Drugs Being Investigated For The Treatment Of Alzheimer's Disease Patients, Mohammed Yasin H, Suresh M, Jalal Hatem Hussein Bayati
Topological Indices And Qspr/Qsar Analysis Of Some Drugs Being Investigated For The Treatment Of Alzheimer's Disease Patients, Mohammed Yasin H, Suresh M, Jalal Hatem Hussein Bayati
Baghdad Science Journal
The quantitative structure-property/activity relationships (QSAR/QSPR) analysis are important for the several properties of estimating/predicting drug-related activities, particularly in the context of the drugs used for the treatment of Alzheimer’s disease. This study uses innovative methods, such as the utilization of -degree and -degree-based topological indices, to evaluate the physicochemical features and attributes of five medications used for the treat Alzheimer’s disease: Tacrine, Donepezil, Rivastigmine, Galantamine and Huperzine A. By reducing the number of descriptors and improving their correlation with a variety of molecular properties, these topological indices provide a unique method for capturing critical molecular structural information. The main objective …
Molluscs From The Magen Avraham Compound, Yafo (Jaffa) (Pp. 385–388), Inbar Ktalav
Molluscs From The Magen Avraham Compound, Yafo (Jaffa) (Pp. 385–388), Inbar Ktalav
'Atiqot
A total of 209 malacological remains were retrieved from the Magen Avraham Compound. The assemblage includes mostly local Mediterranean shells, as well as Indo-Pacific bivalves. Some imported specimens were brought from Europe as raw material for local crafts manufacture; one worked gastropod shell may have been used as an ornament.
Faunal Remains From The Magen Avraham Compound, Yafo (Jaffa) (Pp. 379–383), Nimrod Marom
Faunal Remains From The Magen Avraham Compound, Yafo (Jaffa) (Pp. 379–383), Nimrod Marom
'Atiqot
A small faunal assemblage dating to the Byzantine–Early Islamic and Ottoman periods was uncovered in the Magen Avraham Compound. The animal bones were deposited in an area that used to be part of the agricultural periphery of the town and consist mainly of caprine, cattle and equids. The presence of a relatively high number of equid remains suggests that the assemblage represents the disposal of whole animal carcasses outside the city.
Faunal Remains From Nazareth (Pp. 93–102), Nimrod Marom
Faunal Remains From Nazareth (Pp. 93–102), Nimrod Marom
'Atiqot
The salvage excavations at Nazareth uncovered a faunal assemblage dating from Iron Age II (Stratum III), the late Hellenistic–Early Roman (Stratum II) and Crusader–Mamluk (Stratum I) periods. The assemblage is dominated by sheep and goats, with lower frequencies of cattle. The faunal remains demonstrate tentative evidence for a simple village economy throughout its stratigraphic sequence.
The Faunal Remains From Kefar Gabirol, El-Qubeibe (Pp. 209–223), Nimrod Marom
The Faunal Remains From Kefar Gabirol, El-Qubeibe (Pp. 209–223), Nimrod Marom
'Atiqot
The salvage excavation in Kefar Gvirol, el-Qubeibe, yielded a small faunal assemblage from late Ottoman-period domestic contexts. The faunal remains from the site were studied in terms of taxonomic composition, livestock demography and butchery practices, with reference to assemblage formation processes. The bones from the site provide a rare glimpse into livestock economy and consumption practices at a rural site of the period.
The Fauna From Ḥorbat ‘Ofrat (Pp. 93–104), Nimrod Marom
The Fauna From Ḥorbat ‘Ofrat (Pp. 93–104), Nimrod Marom
'Atiqot
The small faunal assemblage from Ḥorbat ‘Ofrat contains a diverse assortment of bones that were affected by subaerial weathering. A high frequency of cattle was noticed for the Roman strata, suggesting that the economy of the settlement focused on agricultural production. During the transition to the early Byzantine period, a shift was observed, whence sheep and goats became more dominant than cattle, possibly due to an economic shift from agricultural production to a consumption economy that relied on sheep and goats for meat. In the latest occupation at the site, three camel mandibles were found, exhibiting burning patterns that could …
Fauna Remains From The Marketplace At Khan Et-Tujjar (Hebrew, Pp. 57*–62*; English Summary, P. 276), Nimrod Marom
Fauna Remains From The Marketplace At Khan Et-Tujjar (Hebrew, Pp. 57*–62*; English Summary, P. 276), Nimrod Marom
'Atiqot
The salvage excavation near Khan et-Tujjar yielded a small assemblage of animal bones originating in the marketplace that operated at the site from the late Mamluk to the late Ottoman periods. The assemblage is too small to draw conclusions regarding meat consumption at the Khan et-Tujjar marketplace; however, it seems that most of the meat came from cattle and sheep. Several vertebrae exhibit a split along their length, indicating carving by an expert butcher.
Faunal Remains From The Late Chalcolithic, Late Roman, Byzantine And Ottoman Periods At Yehud, Ashkenazi Market (Pp. 1–22), Nuha Agha
'Atiqot
The faunal remains from Yehud were retrieved from several contexts: Late Chalcolithic-period shafts, Roman-period kilns, Byzantine-period houses and pits, and Ottoman-period houses, refuse pits and cesspits. The faunal assemblages from all the periods comprised mainly sheep, goats and cattle. Scant remains of equids and a camel were found in the assemblages from the Roman period onward. Pig remains are absent from both the Roman- and Byzantine-period assemblages, possibly attesting that the inhabitants of the site at that time were Jewish.
Faunal Remains From Khirbat El-’Umdan, Bet Shemesh (Hebrew, Pp. 27*–32*; English Summary, P. 240), Nuha Agha
Faunal Remains From Khirbat El-’Umdan, Bet Shemesh (Hebrew, Pp. 27*–32*; English Summary, P. 240), Nuha Agha
'Atiqot
Excavations at the Chalcolithic site at Khirbat el-’Umdan yielded an assemblage of bones, teeth and horns belonging mostly to mammals: sheep, cattle and pigs. These finding are consistent with the picture that emerged from the analysis of other faunal assemblages from Ghassulian sites in the northern Negev, the coastal plain and Galilee.
The Archaeozoology Of Bronze Age Offerings From Burial Cave 900 In Naḥal Refa’Im, Jerusalem (Pp. 75–100), Liora Kolska Horwitz
The Archaeozoology Of Bronze Age Offerings From Burial Cave 900 In Naḥal Refa’Im, Jerusalem (Pp. 75–100), Liora Kolska Horwitz
'Atiqot
The animal remains recovered during the salvage excavations in Cave 900 were interspersed among human skeletal remains, ceramics, weapons and ornaments. It is apparent that the faunal remains represent exclusively domestic sheep (Ovis aries) and goat (Capra hircus) that were slaughtered as part of Bronze Age mortuary rituals. This assemblage provides additional evidence for the widespread nature of the funeral feast in both the Intermediate Bronze Age and Middle Bronze Age IIB.
Public Baths & Gender Reconstruction In The Mangkunegaran Region Of Solo, Fiera Saffana, Irmawati Marwoto
Public Baths & Gender Reconstruction In The Mangkunegaran Region Of Solo, Fiera Saffana, Irmawati Marwoto
International Review of Humanities Studies
The division of gender roles in space is already evident from the layout of traditional Javanese buildings, which reflects a patriarchal culture where men are at a higher level than women. These gender boundaries and norms are also reflected in the spatial form of public bath in Solo. This research uses the archaeological method by Deetz which consists of data collection, data processing, and data interpretation. Explaining by presenting facts based on data obtained in the field, then data processing is carried out by involving analysis of the field data that has been collected. The last stage is the interpretation …
Graduate School Newsletter Winter 2024-2025, Sandra Spiroff, Martha Caroline Helms
Graduate School Newsletter Winter 2024-2025, Sandra Spiroff, Martha Caroline Helms
Newsletters of the Graduate School
No abstract provided.
Comparing 17Β-Estradiol And Progesterone Concentrations In Young, Physically Active Females: Insights From Plasma Versus Serum Analysis, Samantha N. Rowland, Mariasole Da Boit, Rachel Tan, Liam M. Heaney, Stephen J. Bailey
Comparing 17Β-Estradiol And Progesterone Concentrations In Young, Physically Active Females: Insights From Plasma Versus Serum Analysis, Samantha N. Rowland, Mariasole Da Boit, Rachel Tan, Liam M. Heaney, Stephen J. Bailey
All Faculty Open Access Publications
Serum measurements of 17β-estradiol and progesterone are widely used to verify menstrual cycle status and confirm contraceptive use, often through commercially available immunoassay kits. However, no studies have investigated whether blood collection tube chemistries influence hormone concentrations in young females, despite assays permitting the use of different biofluids with similar reference ranges. In this study, venous blood was sampled from physically active females (n = 25) using Ethylenediaminetetraacetic acid (EDTA) and serum vacutainers, and 17β-estradiol and progesterone concentrations were measured using competitive immunoenzymatic assays. Median plasma concentrations of 17β-estradiol and progesterone were 44.2% (plasma 40.75 vs. serum 28.25 pg/ml) and …
January 30, 2025 Nagpra And Tribal Relations Committee Meeting Minutes, Bryan Morey
January 30, 2025 Nagpra And Tribal Relations Committee Meeting Minutes, Bryan Morey
University NAGPRA and Tribal Relations Committee
Minutes from the January 30, 2025 meeting of Western Kentucky University's NAGPRA and Tribal Relations Committee. The meeting was conducted via Zoom.
Medical School Watercooler Newsletter - January 30, 2025, Lindsay Hughes
Medical School Watercooler Newsletter - January 30, 2025, Lindsay Hughes
Watercooler Newsletter
This is the Thursday, January 30, 2025 edition of the Frederick P. Whiddon College of Medicine's newsletter -- Watercooler.
Contents include:
- Spencer named business manager of Whiddon COM
- Pediatrics residents match at their top choices for fellowships
- SciComm bootcamp to focus on transformative communication
- Whiddon COM researchers and high school students land publication in biology journal
John Proctor Is The Villain Playbill, Providence College Department Of Theatre, Dance, & Film
John Proctor Is The Villain Playbill, Providence College Department Of Theatre, Dance, & Film
Playbill and Promotion
Providence College Department of Theatre, Dance & Film
Angell Blackfriars Theatre
John Proctor is the Villain by Kimberly Belflower
January 30 - February 2, 2025
Director, Noah Putterman
Scenic Design, Samantha Mastrati
Lighting Design, Michael Clark Wonson
Properties Design, Grey Rung
Costume Design, Maxine Wheelock & Christine Britton
Sound Design, Stuart Holland
Choreography, Sarah Putterman
Vocal Coach, Megan Chang
Cast: Raelynn Nix - Olivia Egan; Shelby Holcomb - Isabel Sullivan; Beth Powell - Claire Cunningham; Nell Shaw - Olivia Barbarini; Ivy Watkins - Molly McGoldrick; Mason Adams - Anthony Maldonado; Lee Turner …
Voices For Justice: Firsthand Accounts Of Innocent People Fighting For Access In New York’S Post-Conviction Process, Perlmutter Center For Legal Justice At Cardozo Law
Voices For Justice: Firsthand Accounts Of Innocent People Fighting For Access In New York’S Post-Conviction Process, Perlmutter Center For Legal Justice At Cardozo Law
Perlmutter Center Reports
In 2018, the New York State Court of Appeals’ decision in People v. Natascha Tiger created an insurmountable obstacle for wrongfully convicted individuals pursuing innocence claims. The ruling held that a guilty plea precluded persons accused of crime from challenging their conviction in the absence of newly discovered, exculpatory DNA evidence. This is a troubling fact given 97% of felony convictions and 99% of misdemeanor convictions in New York State are resolved by guilty plea. The National Registry of Exonerations documented that 24% of all exonerated people across the United States pled guilty to crimes they did not commit. According …
Tradeoffs In The Energetic Value Of Neuromodulation In A Closed-Loop Neuromechanical System, Zhuojun Yu, Peter J. Thomas, Hillel J. Chiel
Tradeoffs In The Energetic Value Of Neuromodulation In A Closed-Loop Neuromechanical System, Zhuojun Yu, Peter J. Thomas, Hillel J. Chiel
Faculty Scholarship
Rhythmic motor behaviors controlled by neuromechanical systems, consisting of central neural circuitry, biomechanics, and sensory feedback, show efficiency in energy expenditure. The biomechanical elements (e.g., muscles) are modulated by peripheral neuromodulation which may improve their strength and speed properties. However, there are relatively few studies on neuromodulatory control of muscle function and metabolic mechanical efficiency in neuromechanical systems. To investigate the role of neuromodulation on the system's mechanical efficiency, we consider a neuromuscular model of motor patterns for feeding in the marine mollusk Aplysia californica. By incorporating muscle energetics and neuromodulatory effects into the model, we demonstrate tradeoffs in the …
The Role Of Biofilm Matrix On The Growth, Survival, And Diagnosis In Enterobacteriaceae, Kavi Bharathi R
The Role Of Biofilm Matrix On The Growth, Survival, And Diagnosis In Enterobacteriaceae, Kavi Bharathi R
Theses and Dissertations
Bacteria in nature live together encased in a matrix creating community ecosystems called biofilms, this structured space protects them from hostile environments. This study aimed to understand the role of the biofilm matrix in the growth and survival of Enterobacteriaceae. Our hypothesis proposes that subgroups of individuals within a biofilm can specialize in the production of different matrix components.
Matrix expression is metabolically costly, despite its unicellular simplicity, microbes can coordinate complex behaviour like sharing of matrix between producers and non-producers as an adept evolutionary strategy. Their resilience to stress during biofilm formation was studied to assess their abilities to …
Pulsating Drought And Insect Herbivory Cause Differential Effects On Soybean (Glycine Max) Genotypes That Vary In Canopy Wilting Speed, Jessica Ayala, Manish Gautam, Adrianna Peissel, George Justin, Rupesh Kariyat
Pulsating Drought And Insect Herbivory Cause Differential Effects On Soybean (Glycine Max) Genotypes That Vary In Canopy Wilting Speed, Jessica Ayala, Manish Gautam, Adrianna Peissel, George Justin, Rupesh Kariyat
Entomology and Plant Pathology Faculty Publications and Presentations
As a result of climate change, global temperatures are increasing, and water scarcity is on the rise. Soybean [Glycine max (L.) Merr] is one of the most important crops in the world due to its importance as food and feed. One of the major limiting factors for soybean production is drought, which can cause up to 80% reduction in yield. Therefore, growers and plant breeders are turning to soybean accessions that demonstrate better water use efficiency (WUE). However, in addition to drought, insect herbivory by soybean looper (Chrysodeixis includens, SBL) and fall armyworm (Spodoptera frugiperda, FAW) can also reduce soybean …
Comparison Of Climate Change Awareness Among Coastal Communities In Northern And Southern East Java, Indonesia, Sukma Perdana Prasetya, Ketut Prasetyo, Warsono Warsono, Sarmini Sarmini, Muhammad Turhan Yani, Agus Suprijono, Sugeng Hariyanto, Nasution Nasution, Mohd Hairy Ibrahim
Comparison Of Climate Change Awareness Among Coastal Communities In Northern And Southern East Java, Indonesia, Sukma Perdana Prasetya, Ketut Prasetyo, Warsono Warsono, Sarmini Sarmini, Muhammad Turhan Yani, Agus Suprijono, Sugeng Hariyanto, Nasution Nasution, Mohd Hairy Ibrahim
Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi
One of the important issues in the world today is climate change. Human activities and natural factors mainly cause these changes. The main factor that triggers this phenomenon is the need for more public knowledge in dealing with and anticipating the impacts of climate change. Therefore, this research analyzed the comparative knowledge and perceptions of coastal communities regarding climate change in East Java. Purposive sampling and snowball methods were used to select 110 respondents to complete the survey form. 50 respondents were taken from residents on the Sendang Biru coast, South Malang Regency, and 60 were taken from residents on …
Identification Of Diverse Bacteriophages Associated With Bees And Hoverflies, Rohan A. Bandoo, Simona Kraberger, Cahit Ozturk, Michael C. Lund, Qiyun Zhu, Chelsea N. Cook, Brian Smith, Arvind Varsani
Identification Of Diverse Bacteriophages Associated With Bees And Hoverflies, Rohan A. Bandoo, Simona Kraberger, Cahit Ozturk, Michael C. Lund, Qiyun Zhu, Chelsea N. Cook, Brian Smith, Arvind Varsani
Biological Sciences Faculty Research and Publications
Bacteriophages are the most numerous, ubiquitous, and diverse biological entities on the planet. Prior studies have identified bacteriophages associated with pathogenic and commensal microbiota of honeybees. In this study we expand on what is known about bacteriophages from the lineages Caudoviricetes, Inoviridae, and Microviridae, which are associated with honeybees (Apidae, Apis mellifera), solitary bees of the genus Nomia (Halictidae, Nomia), and hoverflies (Syrphidae). The complete genomes of seven caudoviruses, seven inoviruses, and 288 microviruses were assembled from honeybees (n = 286) and hoverflies in Arizona (n = 2). We used bacterial host predictive …
Filsafat Teknologi Borgmann Sebagai Titik Tolak Etika Bisnis Baru, Antonius Puspo Kuntjoro
Filsafat Teknologi Borgmann Sebagai Titik Tolak Etika Bisnis Baru, Antonius Puspo Kuntjoro
Multikultura
Kelit kelindan antara teknologi dan bisnis telah menghasilkan kekuatan amat besar yang membentuk tatanan baru dalam kehidupan masyarakat dewasa ini. Kekuatan tersebut terwujud dalam perusahaan-perusahaan raksasa berbasis teknologi yang sering disebut sebagai Big Tech, beberapa di antaranya: Amazon, Google, Meta, dan Microsoft. Big Tech memainkan peran sentral dalam mengubah aturan dan nilai dalam masyarakat. Perusahaan-perusahaan besar ini telah memanfaatkan teknologi untuk mengurangi biaya tenaga kerja dan meningkatkan marjin keuntungan. Hal ini makin memperkuat posisi dominan mereka di pasar global. Lebih daripada itu, Big Tech mendorong transisi ke dunia tanpa pekerjaan (post-work world) dengan mengembangkan teknologi yang mengurangi …
The Influence Of Meme Culture On The Perception Of Japanese Music: A Survey Of Dolphin In Town-Kingo Hamada, Salsabila Alfajri, Bambang Wibawarta
The Influence Of Meme Culture On The Perception Of Japanese Music: A Survey Of Dolphin In Town-Kingo Hamada, Salsabila Alfajri, Bambang Wibawarta
International Review of Humanities Studies
The research aims to explore the influence of meme culture on the perception of Japanese music in the digital era, specifically analyzing the impact of meme culture on the song "Dolphin in Town" by Kingo Hamada. This study utilized quantitative methods, with surveys as the main technique for data collection. The results showed that meme culture plays an important role in introducing songs and artists that may not have previously received attention. The study also highlights the diverse impacts of meme culture on the perception of Japanese music, including its influence on popularizing, accepting, and interpreting music in various ways. …
China's Cultural Diplomacy And Its Engagement With The Peranakan Community In Malacca, Kotchaphop Kornphetcharat, Lee Yuen Thien
China's Cultural Diplomacy And Its Engagement With The Peranakan Community In Malacca, Kotchaphop Kornphetcharat, Lee Yuen Thien
International Review of Humanities Studies
China's cultural diplomacy utilizes a range of strategies, including cultural exchange programs, media outreach, and people-to-people interactions, to further its national interests and enhance its international image. The primary aims are to foster a positive perception of China, build mutual understanding and trust with other nations, and expand China's cultural and economic influence. The overseas Chinese community in Southeast Asia has been recognized as a crucial conduit for advancing Chinese cultural policy globally. Recently, the Chinese government has conducted official visits to the Baba & Nyonya Heritage Museum in Malacca, Malaysia, exemplifying its efforts to engage with the local community. …
Exploring Global Research Trends On Smoking And Mental Health: A Bibliometric Analysis, Martaria Rizky Rinaldi, Jelang Hardika
Exploring Global Research Trends On Smoking And Mental Health: A Bibliometric Analysis, Martaria Rizky Rinaldi, Jelang Hardika
Jurnal Ekonomi Kependudukan dan Keluarga
This bibliometric analysis explores global trends, author productivity, institutional and country contributions, citation patterns, and thematic relationships in the literature linking smoking and mental health. Data from the Scopus database were retrieved using specific keyword combinations related to smoking and mental health, resulting in 1,782 eligible articles after filtering for research quality. The study examines publication trends, identifies high-impact studies, and maps thematic clusters in the field. Results indicate a notable increase in publications after 2000, driven by growing recognition of smoking's impact on mental well-being and the integration of mental health considerations in tobacco control policies. Thematic mapping reveals …
Duty Bearer-Right Holder In Law Number 4 Year 2024 On Maternal And Child Welfare In The First Thousand Days Of Life Phase, Tiyas Nur Haryani
Duty Bearer-Right Holder In Law Number 4 Year 2024 On Maternal And Child Welfare In The First Thousand Days Of Life Phase, Tiyas Nur Haryani
Jurnal Ekonomi Kependudukan dan Keluarga
Law No. 4 Year 2024 on Maternal and Child Welfare in the First Thousand Days of Life has been promulgated by the government of the Republic of Indonesia. The regulation guarantees the implementation and fulfilment of the needs of mothers and children in order to improve the quality of human resources. This article aims to map the duty-bearers-rights holders in the draft law on maternal and child welfare in the first thousand days of life. Analysing the position of maternal mothers is the main focus of this research, as maternal mothers are the main subjects in the draft law on …
Molecular Modification Of Queen Bee Acid And 10-Hydroxydecanoic Acid With Specific Tripeptides: Rational Design, Organic Synthesis, And Assessment For Prohealing And Antimicrobial Hydrogel Properties, Song Hong, Sachin B. Baravkar, Yan Lu, Abdul Razak Masoud, Qi Zhao, Weilie Zhou
Molecular Modification Of Queen Bee Acid And 10-Hydroxydecanoic Acid With Specific Tripeptides: Rational Design, Organic Synthesis, And Assessment For Prohealing And Antimicrobial Hydrogel Properties, Song Hong, Sachin B. Baravkar, Yan Lu, Abdul Razak Masoud, Qi Zhao, Weilie Zhou
School of Medicine Faculty Publications
Royal jelly and medical grade honey are traditionally used in treating wounds and infections, although their effectiveness is often variable and insufficient. To overcome their limitations, we created novel amphiphiles by modifying the main reparative and antimicrobial components, queen bee acid (hda) and 10-hydroxyl-decanoic acid (hdaa), through peptide bonding with specific tripeptides. Our molecular design incorporated amphiphile targets as being biocompatible in wound healing, biodegradable, non-toxic, hydrogelable, prohealing, and antimicrobial. The amphiphilic molecules were designed in a hda(hdaa)-aa1-aa2-aa3 structural model with rational selection criteria for each moiety, prepared via Rink/Fmoc-tBu-based solid-phase peptide synthesis, and structurally verified by NMR and LC–MS/MS. …