Digital Commons Network^™

Distinguishing Classes Of Neuroactive Drugs Based On Computational Physicochemical Properties And Experimental Phenotypic Profiling In Planarians, Danielle Ireland, Christina Rabeler, Sagar Rao , '22, R. J. Richardson, Eva-Maria S. Collins

Biology Faculty Works

Mental illnesses put a tremendous burden on afflicted individuals and society. Identification of novel drugs to treat such conditions is intrinsically challenging due to the complexity of neuropsychiatric diseases and the need for a systems-level understanding that goes beyond single molecule-target interactions. Thus far, drug discovery approaches focused on target-based in silico or in vitro high-throughput screening (HTS) have had limited success because they cannot capture pathway interactions or predict how a compound will affect the whole organism. Organismal behavioral testing is needed to fill the gap, but mammalian studies are too time-consuming and cost-prohibitive for the early stages of …

Student’S Disaster Preparedness Of Merapi Volcano, Indonesia Using Learning Simulation Virtual Reality (Lsvr) Model, Andi Irwan Benardi, Sumarmi Sumarmi, Syamsul Bachri, Erni Suharini, Atta Ur Rahman, Sriyono Sriyono, Saiful Amin, Joshua Vincent Gerar Yametis

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

This study evaluates the effectiveness of the Learning Simulation Virtual Reality (LSVR) model in enhancing disaster preparedness for Merapi Volcano and examines the relationship between disaster preparedness and student learning outcomes. Conducted with 120 students from two senior high schools located in disaster-prone areas near Merapi Volcano in Sleman Regency, Yogyakarta Province, Indonesia, the research employed a quasi-experimental design with a pretest-posttest control group setup. Essay-based assessments measured learning outcomes, while surveys gauged disaster preparedness levels. The analysis utilized an independent sample t-test and descriptive statistics, revealing the LSVR model’s strengths in delivering innovative and effective content, appealing design, and …

Kenyon Collegian - January 30, 2025

The Kenyon Collegian

No abstract provided.

Project-Based Flipped Classroom (Pjbfc) For Enhancing 4c Skills In Geography Learning, Ika Listiqowati, Budijanto Budijanto, Sumarmi Sumarmi, I Nyoman Ruja, Exsa Putra, Nor Asniza Ishak

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

This study aims to develop a Project-Based Flipped Classroom (PjBFC) learning model to enhance geography education students' 4C skills when submitting research projects related to geography and geography education. It also seeks to evaluate the effectiveness of the PjBFC model in improving these skills during the submission of research proposals in the field. The development process follows the ADDIE framework, consisting of assessment, design, development, implementation, and evaluation. Two validators validated the PjBFC learning model, along with the learning materials and tools. The implementation phase, or field trial, involved observing the product in use, with 60 students from the Geography …

Groundwater Conservation Zone Model To Support Sustainable Tourism In Coastal Areas: A Case Study In Parangtritis Village, Yogyakarta, Indonesia, Sadewa Purba Sejati, Rivi Neritarani, Mohd Hairy Ibrahim

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

This study aims to determine the environmental characteristics in coastal areas and determine the groundwater conservation zone model in coastal regions. The research was conducted in Parangtritis Village, Bantul Regency, Yogyakarta. The data includes aquifer types, aeration zone materials, and groundwater depth. The data was processed and analysed using Arc GIS Pro software version 2.5. The data were processed by plotting and spatial interpolation techniques to produce thematic maps of environmental characteristics, namely aquifer-type maps, aeration zone material maps, groundwater depth maps, and land use maps. The thematic maps that have been generated are then classified and scored. The classification …

Plasmids Encode And Can Mobilize Onion Pathogenicity In Pantoea Agglomerans, Gi Yoon Shin, Jo Ann Asselin, Amy Smith, Brenna Aegerter, Teresa Coutinho, Mei Zhao, Bhabesh Dutta, Jennie Mazzone, Ram Neupane, Beth Gugino, Christy Hoepting, Manzeal Khanal, Subas Malla, Claudia Nischwitz, Jaspreet Sidhu, Antoinette Machado Burke, Jane Davey, Mark Uchanski, Michael L. Derie, Lindsey J. Du Toit, Stephen Stresow-Cortez, Jean M. Bonasera, Paul Stodghill, Brian Kvitko

Biology Faculty Publications

Pantoea agglomerans is one of four Pantoea species reported in the USA to cause bacterial rot of onion bulbs. However, not all P. agglomerans strains are pathogenic to onion. We characterized onion-associated strains of P. agglomerans to elucidate the genetic and genomic signatures of onion-pathogenic P. agglomerans. We collected > 300 P. agglomerans strains associated with symptomatic onion plants and bulbs from public culture collections, research laboratories, and a multi-year survey in 11 states in the USA. Combining the 87 genome assemblies with 100 high-quality, public P. agglomerans genome assemblies we identified two well-supported P. agglomerans phylogroups. Strains causing severe …

Microbiome Metabolic Capacity Is Buffered Against Phylotype Losses By Functional Redundancy, Kayla Cross, Noelle Beckman, Benjamin Jahnes, Zakee L. Sabree

Biology Faculty Publications

Many animals contain a species-rich and diverse gut microbiota that likely contributes to several host-supportive services that include diet processing and nutrient provisioning. Loss of microbiome taxa and their associated metabolic functions as result of perturbations may result in loss of microbiome-level services and reduction of metabolic capacity. If metabolic functions are shared by multiple taxa (i.e., functional redundancy), including deeply divergent lineages, then the impact of taxon/function losses may be dampened. We examined to what degree alterations in phylotype diversity impact microbiome-level metabolic capacity. Feeding two nutritionally imbalanced diets to omnivorous Periplaneta americana over 8 weeks reduced the diversity …

Hypoxia Signaling In The Adipose Tissue, Phu M Huynh, Fenfen Wang, Yu A An

Faculty, Staff and Student Publications

Obesity per se is rapidly emerging all over the planet and further accounts for many other life-threatening conditions, such as diabetes, cardiovascular diseases, and cancers. Decreased oxygen supply or increased relative oxygen consumption in the adipose tissue results in adipose tissue hypoxia, which is a hallmark of obesity. This review aims to provide an up-to-date overview of the hypoxia signaling in the adipose tissue. First, we summarize literature evidence to demonstrate that hypoxia is regularly observed during adipose tissue remodeling in humans and rodent models with obesity. Next, we discuss how hypoxia-inducible factors (HIFs) are regulated and how adipose tissues …

One Health Investigation Following A Cluster Of Crimean-Congo Haemorrhagic Fever, North Macedonia, July To November 2023, Dejan Jakimovski, Pavle Banović, Katerina Spasovska, Goran Rangelov, Marija Cvetanovska, Fadil Cana, Verica Simin, Ivana Bogdan, Dragana Mijatović, Aleksandar Cvetkovikj, Igor Djadjovski, Iva Christova, Eleftherios Meletis, Polychronis Kostoulas, Brigitta Zana, Zsófia Lanszki, Tamás Görföl, Zsófia Tauber, Gábor Kemenesi

School of Biomedical Sciences

Background: Crimean–Congo haemorrhagic fever(CCHF) is a severe illness characterised by fever,bleeding and high case-fatality rates. The disease iscaused by CCHF virus (CCHFV), transmitted by ticksand infectious body fluids and tissues. Aim: After CCHFwas diagnosed in three persons in 2023, we aimed toinvestigate the presence of antibodies against CCHFVin healthcare workers (HCW), sheep and goats, andof CCHFV in ticks, in an area in North Macedonia andcharacterise virus strains. Methods: In 2023, we collected blood samples from HCWs involved in treating CCHF patients and sera and ticks from sheep andgoats in the village in North Macedonia where theindex case resided. The blood …

Online Media Sentiment Analysis Of Shrimp And Salmon In The United States, Jingjing Tao, Kwamena K. Quagrainie

Department of Agricultural Economics Faculty Publications

There is a growing interest in the U.S. seafood and aquaculture market; however, studies utilizing online information to understand this market are limited. This study employs online media analytics to obtain insights into consumer perceptions and potential demand signals for shrimp and salmon in the U.S. Our results show that platform X is the preferred medium for shrimp and salmon discussions, with shrimp's physical quality and salmon's environmental impact being the two major perception drivers. Additionally, autoregressive modeling is conducted to explore the dynamics of net sentiments. Farmed shrimp and salmon consistently exhibit lower net sentiments compared to their wild …

A New Species Of Parrot Snake, Leptophis (Serpentes: Colubridae) From The Brazilian Cerrado, Nelson R. Albuquerque, Roullien H. Martins, Priscila Carvalho, Donald B. Shepard, Diego J. Santana

Biological Sciences Faculty Publications and Presentations

We describe a new species of Leptophis (parrot snake) from the Cerrado ecoregion of Brazil. The new species, L. mystacinus sp. nov., differs from all other congeners in the following unique character combination: two Spectrum Green (129) to Light Parrot Green (133) dorsolateral stripes separated by a Buff (5) vertebral stripe, usually continuous onto the tail; loreal scale absent; postocular stripe Jet Black (300), wide and long (up 11 scales long onto nuchal region); maxillary teeth 21-25; ventrals 158-173; subcaudals 141-164; black spots on head absent; supracephalic plates of head not edged with black pigment; adult color pattern lacking dark …

The Potential Escalation Of Strategic Partnership Conflicts In The Indo-Pacific Region From The Aukus Trilateral Defense Pact, Yodia Adriatami Edwina, Yossica Ariatami Edwina

Indonesian Journal of International Law

The aggressiveness demonstrated by China in the South China Sea has caused instability and tension in military conflicts within the Indo-Pacific region. This aggressiveness was specifically demonstrated with the aim of controlling the sea in the region and considered a threat to maritime security, In an effort to balance the Indo-Pacific region against the aggressive attitude of China, the Trilateral Defense Pact agreement was made by Australia, United Kingdom, and United States. Despite the presented advantages associated with the effort, it is important to state that the agreement has raised concerns in Indonesia regarding its implications for maritime stability and …

“It Is Such A Hidden Curriculum Thing”: Graduate Students’ Perceptions Of Publishing, Christy Caldwell, Martha Stuit, Lucia Orlando

Journal of Graduate Librarianship

Becoming published authors presents a learning curve for graduate students. Publishing literacy is part of the hidden curriculum of graduate school because publishing is generally not taught consistently but more commonly through ad hoc conversations with advisors, advice from peers, and the occasional workshop. Our study surveyed graduate students at the University of California, Santa Cruz (UCSC) who had already published or were expecting to publish journal articles. Survey questions asked students about the publishing process, defined by us as the stage of the post-writing process when a manuscript is ready to publish. Our data demonstrate that publishing expectations are …

The Pulse, 2002, V10 N3, Summer, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 2002, V10 N4, Fall, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 2001, V12 N4, Fall, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 2000, V10 N4, Fall, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 2000, V10 N1, Winter, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 1998, V8 N4, Fall, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 1998, V8 N3, Summer, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 1997, V7 N4, August, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 1995, V5 N3, Summer, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 1991 Winter, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 1991 Spring, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 1991 Fall, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 1990 Winter, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 1989 Fall, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 1983, N5, Fall, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

The Pulse, 1984, N6, Summer, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.

Investigating Suicide Risk Factors Among Appalachian West Virginian Adults, Erin D. Caswell, Angela M. Dyer, Summer D. Hartley, Caroline P. Groth, Mary Christensen, Sahiti K. Tulabandu, Bryce K. Weaver, Ruchi Bhandari

Journal of Appalachian Health

Introduction: Suicide rates in the United States have increased over the past two decades, with rural areas, particularly the Appalachian Region, facing unique challenges that elevate suicide risk. These include economic hardships, social isolation, and limited access to mental health services.

Purpose: This study addresses critical gaps in understanding lifetime suicide risk in West Virginia (WV), a predominantly rural state entirely within the Appalachian Region. By identifying the factors driving urban-rural differences in suicide risk, this research seeks to inform interventions tailored to the state's distinct needs and provide insights applicable to the broader Appalachian Region

Methods: Using 2021 Mountain …