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Evaluation Of Anticonvulsant Activity Of Polyherbal Formulation Based On Ayurvedic Formulation, Arka Ghosh, Ashish Mishra, Ankit Seth, Santosh Kumar Maurya

Indian Journal of Health Sciences and Biomedical Research KLEU

Background:

The aim of the present study was to develop a polyherbal formulation for epilepsy. Present polyherbal formulation (PHF) (containing

Operculina turpethum

(L.) Silva Manso,

Mimosa pudica

L.,

Uraria picta

(Jacq.) DC.,

Cajanus cajan

(L.) Millsp, and

Lawsonia inermis

L.) is based on an ayurvedic formulation "

Brihad Panchagavya Ghrita

" indicated for epilepsy.

Materials and Methods:

To establish the scientific basis of mechanism, we examined the effects of methanolic extract of PHF (100, 200, and 400 mg/kg, p.o.) on maximal electric shock (MES), pentylenetetrazol (PTZ), and isoniazid (INH)-induced convulsions as well as gamma-aminobutyric acid (GABA)-glutamate level in the brain …

Role Of, Bhrigu Kumar Das, Basavaraj C. Koti, Pramod C. Gadad

Indian Journal of Health Sciences and Biomedical Research KLEU

Objective:

This study aims to evaluate the role of

Lycopersicon

esculentum

in diethylnitrosamine (DEN)-induced and phenobarbital (PB)-promoted hepatocellular carcinoma.

Materials and Methods:

The hepatocarcinogenesis was induced in male Wistar albino rats by DEN (single injection, 200 mg/kg, i.p

.

); 2 weeks later, 0.05% w/v of PB was administered through drinking water for 16 weeks. The treatment group rats received a similar dosage as above along with enzymatic extract of

L.

esculentum

(250 mg/kg body weight p.o.) at 3

rd

week onward. The carcinogenesis was evaluated by estimating biochemical markers such as alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase …

An Overview On Sildenafil And Female Infertility, Jyoti M. Benni, Paragouda A. Patil

Indian Journal of Health Sciences and Biomedical Research KLEU

Endometrial thickness (EM) is one of the strongest predictors of implantation rate and ongoing pregnancy success rate. The endometrial growth is dependent on the uterine blood flow and angiogenesis. Recently, some reports discussed the possible beneficial effects of sildenafil citrate on EM. Sildenafil citrate leads to smooth muscle relaxation and vasodilation. Because of these biological properties, it is a potential candidate for female infertility, especially in the management of thin endometrium, which leads to low implantation and pregnancy rates. An updated electronic search was performed through PUBMED, MEDLINE, and COCHRANE and focused on peer-reviewed, randomized controlled trials, and observational cohort …

Effect Of Β-Asarone On Diethylnitrosamine-Induced Hepatocellular Carcinoma In Rats, Sebashree R. Roy, Pramod C. Gadad

Indian Journal of Health Sciences and Biomedical Research KLEU

Aim:

This study was designed to evaluate the effect of β-asarone on diethylnitrosamine (DEN) induced and phenobarbital-promoted hepatocellular carcinoma in rats.

Materials and Methods:

The experiments were carried out with two models, i.e., tumor initiation and promotion model. The effect of β-asarone was evaluated by the estimation of food and water consumption, body and liver weights, liver function indicators such as aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, total and direct bilirubin, cancer indicators such as alpha-fetoprotein, DNA, RNA, and total liver protein content, and histopathological studies.

Results:

The results showed that the levels of liver function indicators were brought down …

Design, Formulation And Evaluation Of Carboxy Methyl Tamarind Based, Fatima S. Dasankoppa, Seema Kujur, Hasan Pasha Nazeer Ahmed Sholapur, Vilas G. Jamakandi

Indian Journal of Health Sciences and Biomedical Research KLEU

Introduction:

A major problem in ocular therapeutics is the attainment of optimum drug concentration at the site of action, which is compromised mainly due to precorneal loss resulting in only a small fraction of the drugs being absorbed. The effective dose administered may be altered by increasing the retention time of medication into the eye by using in situ gel forming polymeric systems.

Materials and Methods:

In the present investigation, an attempt has been made to design, formulate, and evaluate in situ gelling-based ophthalmic drug delivery system dorzolamide hydrochloride to enhance the precorneal retention and to improve the ocular bioavailability. …

Medicinal Plants And Related Developments In India A Peep Into 5-Year Plans Of India, Janmejaya Samal

Indian Journal of Health Sciences and Biomedical Research KLEU

Medicinal herbs/plants or the herbal drugs refer to the use of plant and plant-based products for the management of common ailments. World Health Organization has defined herbal medicines as finished labeled medicinal product that contains an active ingredient, aerial, or underground parts of the plant or other plant material or combinations. In India, more than 70% of the population uses herbal medicine for their health-related problems. Many of the institutions adopt “reverse pharmacology” approach to study the clinical efficacy of medicinal plants and their pragmatic utility in healthcare. Moreover, the herbal therapeutics constitutes a major share of all the officially …

Fundamental Tenets Of Epidemiology In Ayurveda And Their Contemporary Relevance, Janmejaya Samal

Indian Journal of Health Sciences and Biomedical Research KLEU

Background:

Ayurveda, the science of life, is the most ancient medical doctrine of human civilization. Some of the basic principles described in Ayurveda are still the same as today's medical science. Ayurveda does not have a specific text as epidemiology, but the principles described in piecemeal can be compiled, analyzed, and interpreted in the light of modern theories of epidemiology.

Objective:

An initial systematic literature review by the help of internet-based search engines revealed very negligible work in the field of Ayurveda and epidemiology. Hence, an attempt was made to analyze various principles of Ayurveda relevant to epidemiology and interpret …

Malarial Trend In Dakshina Kannada, Karnataka An Epidemiological Assessment From 2004 To 2013, Shivakumar, B. V. Rajesh, Arun Kumar, Muktha Achari, Suman Deepa, Navya Vyas

Indian Journal of Health Sciences and Biomedical Research KLEU

Background:

Malaria is one of the main causes for morbidity in India and many of the tropical countries. Dakshina Kannada in Karnataka is one of the Malaria endemic districts. Various efforts to contain the transmission of this deadly disease by National Vector Borne Disease Control Program (NVBDCP) has been effective up to an extent.

Methods:

A retrospective report based study over a period of ten years was conducted in Dakshina Kannada district. The community based data of confirmed cases of malaria was collected and analysed.

Results:

Highest cases of Malaria were recorded in 2005 (16,154). The incidence of Malaria ranged …

Diagnosis And Treatment Of A Teenager With Comorbid Depression And Anorexia Nervosa, A. O. Coker, O. O. Coker

Indian Journal of Health Sciences and Biomedical Research KLEU

This is a case of an 18-year-old female Nigerian student who presented to the emergency department with symptoms of depression that was subsequently diagnosed with anorexia nervosa (AN). The clinical features, diagnosis, and complications of AN were also discussed. This case report supports the suggestions that anorexia previously unreported in Nigeria and other sub-Saharan countries may be underreported. Therefore, general practitioners and family physicians should be aware of the emergence of this illness in Nigeria in order to identify and treat adolescents with this illness.

Fluroscence A Cryptic Puzzle, Manasi Chetan Mundada, Faiq Ahmed, G. S. Devi, Sudha Murthy, M. V. T. Mohan

Indian Journal of Health Sciences and Biomedical Research KLEU

Acute promyelocytic leukemia (APL) has defined biology and clinical course that is, distinct from the other forms of acute myelogenous leukemia. It may present with potentially devastating coagulopathy and the sensitivity to retinoid differentiating agents, including all-trans retinoic acid and arsenic trioxide, hence a fast and definite diagnosis is imperative. Reciprocal 15, 17 translocation creates a

PML/RARA

fusion gene on the derivative chromosome 15, which can be detected by various molecular tests such as cytogenetics, fluroscence

in-situ

hybridization (FISH), reverse transcriptase-polymerase chain reaction. We present here a diagnostically challenging case, both morphologically and immunophenotypically proven to be APL, which was …

Knowledge Of Pregnant Women About Congenital Anomalies A Cross-Sectional Study In North Of Iran, Pourmohsen Masoumeh, Khoshravesh Vahid, Alavi Majd Hamid, Khaleghinezhad Khosheh, Khayat Samira

Indian Journal of Health Sciences and Biomedical Research KLEU

Background:

Proper knowledge about risk factors and prevention of congenital malformations in pregnant women can lead to primary prevention of disease. The aim of this study was to explore pregnant women's knowledge about congenital anomalies, risk factors, and prevention in relation to their sociodemographic profile.

Materials and Methods:

A cross-sectional study of the expecting mother's population was conducted over 3 months. Data collection was done through a questionnaire completed in face to face interviews using simple nonrandom sampling method in 150 pregnant women who visited the prenatal clinics in Rasht. The questionnaire contained 6 questions about specific knowledge and 12 …

Formulation And Evalution Of New Polyherbal Toothpaste For Oral Care, S. Abhay, Basavaraj M. Dinnimath

Indian Journal of Health Sciences and Biomedical Research KLEU

Aim and Objective:

The main objective of this research was to formulate medicated polyherbal toothpaste with better antimicrobial activity from natural sources for dental infections.

Materials and Method:

The hydroalcoholic extracts of apple peel, lemon peel, orange peel, banana peel was carried out and the formulated toothpaste from the above extracts were subjected for antimicrobial activity study against Gram-positive bacteria (

Staphylococcus aureus, Enterococcus faecalis, Streptococcus mutans

) and Gram-negative bacteria (

Porphyromonas gingivalis

).

Results:

Antibacterial activity of the toothpaste was determined by the 2-fold serial dilution method. All the extract has showed good antimicrobial against

P. gingivalis

, …

Cardioprotective Effect Of Gallic Acid Against Doxorubicin-Induced Myocardial Toxicity In Albino Rats, J. M. Kulkarni, A. H. M. Viswanatha Swamy

Indian Journal of Health Sciences and Biomedical Research KLEU

Objective:

The present study was designed to investigate the protective and potential effect of gallic acid against doxorubicin (DOX) induced cardiotoxicity.

Materials and Methods:

Adult Wistar albino rats of either sex weighing 150-200 g were used in this study. DOX administered intraperitoneally in six equal injections (each containing 2.5 mg/kg at 48 h intervals) to total cumulative doses of 15 mg/kg over a period of 2 weeks to induce cardiotoxicity. The estimation of cardiac and lipid biomarkers of both control and treated animals were observed.

In vivo

antioxidant parameters such as glutathione, superoxide dismutase, catalase, and malondialdehyde were also monitored. …

A Comparative Study, Saikat Sen, Raja Chakraborty, Bitul Borah, B. K. Dey, Bapi R. Sarkar, B. J. Sahariah

Indian Journal of Health Sciences and Biomedical Research KLEU

Background and Purpose:

Momordica

charantia

L. (Cucurbitaceae) is used as both food and management of diverse human diseases science ancient time, including in the treatment of worm infection. This study was aimed to evaluate the comparative anthelmintic and anti-oxidant activity of juice and extracts of whole fruit, peels, and seed of

M.

charantia

.

Materials and Methods:

In vitro

anthelmintic activity of methanol extract of whole fruit, fruit peels, seed and fresh juice whole fruit, peels of

M.

charantia

was investigated against Indian adult earthworms (

Eisenia

foetida

). Extracts and juices are also investigated for their anti-oxidant activity using …

Gmos And Public Perception: College Students’ Opinions And Knowledge Of Genetic Engineering, Serene M. Cheng

RURALS: Review of Undergraduate Research in Agricultural and Life Sciences

Genetically modified organisms (GMOs) can be developed and implemented to address significant global challenges, including nutrient deficiencies, climate change, and crop disease. However, widespread opposition has prevented the success of GMOs. We believe this opposition is strongly connected to a lack of understanding about genetics in general, which has been reflected by previous studies.

In this study, we considered the relationship between GMO support and genetics knowledge by comparing results from a brief quiz and responses to prompts relating to GMOs. Using a survey of college students, we found that support for GMOs and general knowledge of genetics are positively …

Cars And Trucks: Driving A Paradigm Shift In Hematologic Malignancies, Christine Charek, Tia Solh

Lynchburg Journal of Medical Science

Hematologic malignancies account for a significant number of annual cancer diagnoses and deaths across the globe. Historically, the prognosis for relapsed and/or refractory disease after standard therapies, such as chemotherapy and/or radiation, was poor. Chimeric antigen receptor (CAR) T-cell therapy offers an additional treatment option. While promising, this type of immunotherapy also comes with potentially severe side effects, toxicities, and limitations. A better understanding of the development, administration, and management of patients undergoing treatment can provide the general clinician with the knowledge to assist within a multidisciplinary team to ultimately improve patient outcomes.

The Effects Of E-Cigarettes And Oxidative Stress On Cognitive Function And Adolescent Academics, Alexis A. Kaminsky Jr.

Lynchburg Journal of Medical Science

Electronic cigarettes are the fastest growing method of tobacco consumption in the United States despite an overall decline in smoking rates. Evidence has shown that enticing flavor and trendy marketing campaigns have increased use among younger consumers. Nicotine use is a risk factor among younger individuals for damage to brain development and cognitive impairment, and electronic cigarettes are no exception. This paper attempts to review and clarify previously observed health impacts of electronic cigarette use among younger individuals, as measured by academic grades and scores. A focus on the effect of oxidative stress on the body and the resulting academic …

The Role Of Glp-1ras In Depression Among Patients With Metabolic Conditions, Madge Fleurimond Cemelus Dmsc, Pa-C

Lynchburg Journal of Medical Science

ABSTRACT

The regular co-occurrence of depression with metabolic syndrome (Mets) results in complicated treatment circumstances and raises cardiovascular diseases and type 2 diabetes risks. GLP-1RAs demonstrate potential as an innovative treatment for depression because they have both anti-inflammatory properties and neuroprotective capabilities. This evaluation examines the advantages and results of GLP-1RAs in treatment effectiveness compared to CBT among patients with MetS. The research used PubMed and CINAHL databases to find peer-reviewed studies from 2021 until 2025. The research included the search terms “GLP-1 receptor agonists” together with “depression,” “metabolic syndrome,” and “cognitive behavioral therapy,” among other relevant terms. Applying GLP-1RAs …

Binge Eating Disorder: A Clinical Review, Michell Mcdiffett Mshs, Pa-C

Lynchburg Journal of Medical Science

Binge eating disorder (BED) is the most common eating disorder (ED) in the United States (U.S.) and is characterized by recurrent episodes of eating a larger than normal amount of food in a discrete period of time and includes a sense of loss of control over food intake. BED is often comorbid with serious somatic and psychiatric disorders and is associated with reduced quality of life and excess mortality. Some consider BED a public health concern due to frequent co-occurrence with obesity and worse outcomes in those populations. The diagnosis is often delayed due to shame and underreporting of symptoms …

A Study To Evaluate The Effectiveness Of Structured Counseling Program On Quality Of Life Among Hiv Infected Postnatal Mothers, Sudha Raddi, Ratna Prakash, Shivaraj Dandagi

Indian Journal of Health Sciences and Biomedical Research KLEU

Objectives of the study were to evaluate the effectiveness of structured counseling program on quality of life (QoL) and to find out the association between pre test level of QoL and selected demographic variables.

A study was conducted on 80 HIV infected postnatal mothers by using the True experimental Solomon four group research design and data were analyzed in terms of descriptive and inferential statistics.

In conclusion, it was inferred that the structured counseling program was effective on quality of life among HIV infected postnatal mothers and selected variables did not have significant association with QoL

Preventing Bacterial Infections In The Society Lessons To Be Learnt, Gajanan S. Gaude

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

Noda News April 2005

New Orleans Dental Association News

New Orleans Dental Association (NODA) News includes regular columns with regional news impacting the New Orleans membership including: columns from the President and Executive Director, feature articles relating to the field of dentistry, association events and upcoming activities, component news, continuing education opportunities, and classifieds.

Multi-Modal Covid-19 Detection Using Cough Sounds And Medical Information With Attention-Enhanced Deep Learning, Mohamed Talaat Saidahmed, Reda Elbasiony, Marwa Reda Bastwesy, Asmaa Aly Hagar

Journal of Engineering Research

The COVID-19 pandemic has highlighted the need for fast, non-invasive, and cost-effective diagnostic tools. Cough sounds, as a prominent symptom of respiratory diseases, present a promising modality for automated COVID-19 detection. In this study, we propose a novel multi-modal deep learning framework for COVID-19 detection that leverages cough sounds and patient-specific medical information. Our approach extracts two types of acoustic features—Mel-Frequency Cepstral Coefficients (MFCCs) and Mel spectrograms—and integrates them with clinical metadata to improve diagnostic ac-curacy. The MFCC branch employs 1D convolutional layers followed by Efficient Channel Attention mechanism. The Mel spectrogram branch utilizes ResNet-50 combined with ECA to capture …

Monitoring And Documenting Local Legislation Role In Urban Governance To Keep Green Areas In New Cities, Eman Gameel Abu Eleneen, Ahmed Aboulsaadat

Journal of Engineering Research

Cities that are poorly planned, managed, and controlled, can become centers of poverty, inequality, and conflict. " Good Urban Governance refers to the various ways in which individuals and institutions, both public and private, plan and manage the city's common affairs promoting the concept of "Inclusive City” by advocating "enabling approach" Decentralization, involvement, partnerships, capacity building, and networking. The study discusses urban governance conceptualization and assesses it depending on five principles effectiveness, accountability, equity, participatory and security. Also, it studies green space conservation and investigates the main challenges that faces conserving green spaces and implementing strategies. It explores new Egyptian …

A Comparative Study Of Green Urban Planning As An Approach For Urban Sustainability, Shoroq Adel Ali, Walaa Ahmed Nour Prof, Ahmed H. Aboulsaadat

Journal of Engineering Research

The world's cities deal with numerous issues brought on by rapid and bad urban planning, which leading to issues that weren't just urban planning problems but also had an impact on the environment, society, and the economy. As a result, new types of urban planning have developed including sustainable urban planning and green urban planning, which is reflected in the basic components of enhancing the individuals wellbeing without compromising the environmental aspect. Furthermore, this study discusses the identification and the latest trends of urban planning. Then, the study presented the concept of green urban planning and sustainable urban planning. As …

Evaluation Of Machine And Deep Learning Models For Predicting Water Distillate Rate, Ghada Hamisa

Journal of Engineering Research

Freshwater scarcity has become a critical global challenge due to rapid population growth and environmental pollution caused by industrial and urban expansion. Solar stills offer a sustainable solution by desalinating impure water using solar energy, making them valuable for domestic, industrial, and academic applications. However, traditional methods for optimizing solar still performance face significant limitations, including time-consuming experimental data collection, computational inaccuracies, and high development costs. To address these challenges, this study leverages machine learning (ML) and deep learning (DL) techniques to predict the distilled water production rate of solar stills before physical construction or modification. A heat pump solar …

On The Possibility Of Predicting The Approximate Fatty Acid Composition Of Blends Based On The Iodine Number, Adiba M. Serkaeva, Akhror A. Abdurakhimov, Nafisa S. Husanova, Kamar P. Serkaev

CHEMISTRY AND CHEMICAL ENGINEERING

The aim of the study was to conduct research to determine the possibility of predicting the approximate fatty acid composition of blends based on the iodine number. The fatty acid composition was determined by the chromatographic method and the results were subsequently used to identify the composition of blends by determining the iodine number. The iodine number was determined by calculation and titrimetric methods, comparing the differences between the obtained values. The detected deviations in values between the two methods do not exceed 0.4%, which means that it is possible to predict the approximate fatty acid composition of blends based …

Preparation Of Nano-Sized Silver Particles By Electrolysis From Silver-Containing Electrical Scrap, Umar A. Yakhyaev, Mastura Kh. Aripova, Ripsime V. Mkrtchyan, Dilrabo A. Mukhtorova

CHEMISTRY AND CHEMICAL ENGINEERING

The aim of the study was preparation of nanosized silver particles by electrolysis from silver-containing scrap from electrical engineering production. For this purpose, at the first stage, silver particles with a size of 0.2–2 microns were obtained by the cementation method, confirmed by the results of scanning electron microscopy. A silver anode for the electrolysis unit was created from the obtained silver particles by the melting method. At the second stage, electrolysis was carried out on a unit with rotating electrodes, in which the cathode was made of platinum. Optimum conditions for the electrolysis process, carried out at a voltage …

Digital Infrastructure For The Regenerative Movement: A Case Study Of The Mycelium Learning Network, Abigail Karparis

Journal of Nonprofit Innovation

The regenerative movement is gaining momentum worldwide, driven by communities working to restore ecological and social systems through place-based, culturally rooted action. Yet many of the groups leading this work, especially in the Global South or in hyper-local contexts, remain digitally invisible due to structural barriers, including limited access to appropriate technology, funding constraints, and misalignment between available tools and local values. Conventional digital infrastructures often exclude or marginalize these efforts, leaving regenerative practitioners disconnected from each other and from potential sources of support.

This article explores these challenges and presents a case study response: the co-creation of accessible, relational …

Transformative Fan Literature, Queer Identity Development And Sexual Wellness: A Qualitative Interview Study With Adults, Gabrielle Piela

ETD Collection

No abstract provided.