Digital Commons Network^™

Gallium-Containing Bioactive Glasses: Their Influence On Ion Release And The Bioactivity Of Resulting Glass Polyalkenoate Cements, Lana Margaret Placek, Danielle Lee Perry, Mark Robert Towler, Anthony William Wren

Chemical and Biochemical Engineering Faculty Research & Creative Works

A series of glasses (0.48SiO2 − [0.40-x]ZnO − 0.12CaO-xGa2O3, x = 0, 0.8, 0.16) was developed to formulate a series of Ga-containing glass polyalkenoate cements (GPCs). The solubility of GPCs was tested using DI water, and it was found that the sample containing the highest mol% of Ga, LGa-2, had the most Ga ion release. The GPCs were incubated in SBF, and SEM/EDS analysis revealed that the at% of P increased, while the at% of Si decreased, highlighting the CaP precipitation on the GPC surface. The at% of Ga also decreased, reinforcing the Ga release from the GPC. Cellular testing …

Leveraging Chorionic Villus Biopsies For The Derivation Of Patient-Specific Trophoblast Stem Cells., Kaela Varberg, Ayelen Moreno-Irusta, Allynson Novoa, Brynne Musser, Joseph M. Varberg, Jeremy P. Goering, Irfan Saadi, Khursheed Iqbal, Hiroaki Okae, Takahiro Arima, John Williams, Margareta D. Pisarska, Michael J. Soares

Manuscripts, Articles, Book Chapters and Other Papers

Human trophoblast stem (TS) cells are informative in vitro models for the generation and testing of biologically meaningful hypotheses. The goal of this project was to derive patient-specific TS cell lines from clinically available chorionic villus biopsies. Cell outgrowths were captured from human chorionic villus tissue specimens cultured in modified human TS cell medium. Cell colonies emerged early during the culture and cell lines were established and passaged for several generations. Karyotypes of the newly established chorionic villus-derived trophoblast stem (TS^CV) cell lines were determined and compared to initial genetic diagnoses from freshly isolated chorionic villi. Phenotypes of …

Advances In Noninvasive Imaging For Detecting Radiation-Induced Lung Injury (Rili), Austen Nissen, Said H. Audi, Anne V. Clough, Brian Fish, Amit Joshi, Meetha Medhora, Jason Walter Sidabras, Heather A. Himburg

Biomedical Engineering Faculty Research and Publications

Purpose: Dr. Richard Hill performed pioneering work in the field of radiation-induced normal tissue injury to the lung including noninvasive imaging studies aimed at identifying imaging biomarkers of radiation-induced lung injury (RILI). RILI is a life-threatening toxicity of radiation exposure relevant to both cancer patients undergoing thoracic radiation therapy (RT) and victims of accidental radiation exposure. The ability to detect RILI noninvasively has the potential to guide treatment planning for RT and, in the case of victims of acute radiation exposures, inform the decision to start mitigative therapies. As part of this special issue of IJRB honoring Dr. Hill’s many …

Designing A Portable And Accessible Diffuse Reflectance Spectroscopy System For Real-Time Detection Of Cervical Intraepithelial Neoplasia, Allison Scarbrough, Diana Moses, Tongtong Lu, Bing Yu

Biomedical Engineering Faculty Research and Publications

Significance: Over 80% of cervical cancer cases occur in lower-to-middle income countries (LMIC’s). This is partly because current screening techniques lack affordability, accessibility, and/or reliability for use in LMIC’s.

Aim: To develop an optical technique for cervical cancer screening that is affordable, accessible, and reliable for use in LMIC’s.

Approach: We developed a portable diffuse reflectance spectroscopy (DRS) system, which costs < $2500 USD to manufacture, and employs a Raspberry Pi to extract the absorption (μ_a) and reduced scattering (μ'_s) coefficients of biological tissue. The system was subject to travel and intentional rough handling. It was further used to capture 320 DRS spectra taken from 64 tissue-mimicking phantoms. Two …

Student Life, Saint Mary's College Of California

Academic Catalog

No abstract provided.

Undergraduate Curriculum, Saint Mary's College Of California

Academic Catalog

No abstract provided.

Majors, Minors, And Certificates, Saint Mary's College Of California

Academic Catalog

No abstract provided.

Undergraduate Academic Regulations, Saint Mary's College Of California

Academic Catalog

No abstract provided.

Financial Aid, Saint Mary's College Of California

Academic Catalog

No abstract provided.

2025-2026 Academic Catalog, Saint Mary's College Of California

Academic Catalog

No abstract provided.

Course Descriptions, Saint Mary's College Of California

Academic Catalog

No abstract provided.

Cazyme Gene Cluster Diversity In Human Gut Microbiome, Yi Xing

Department of Food Science and Technology: Dissertations, Theses, and Student Research

In gut microbiome research, carbohydrate-active enzyme gene clusters (CGCs) have emerged as key functional units for understanding microbial glycan degradation. Unlike taxonomic or broad pathway annotations, CGCs offer gene-cluster-level resolution and capture substrate-specific microbial functions. However, their diversity and distribution in relation to host metabolic phenotypes, such as obesity, remain poorly characterized. This study tests the hypothesis that the composition and abundance of fiber-targeting CGCs vary between obese and healthy human gut microbiomes, reflecting distinct microbial carbohydrate utilization strategies. To examine this, we constructed a high-quality reference CGC dataset comprising 94,019 clusters from the Unified Human Gastrointestinal Genome and profiled …

Unm Pathology, Pathfinder Summer 2025, Unm Department Of Pathology

Newsletters

No abstract provided.

Artificial Intelligence And Humanoid Robotics: Bioethical Implications Of Replacing Human Agency In Healthcare And Beyond, Sara Feizyab, Gabriele Bonetti, Maria Chiara Medori, Cecilia Micheletti, Immacolata De Luca, Kevin Donato, Jan Miertuš, Mehmet Sait Dundar, Miroslava Vráblová, Gary Henehan, Richard Brown, Robert Marks, Stanislav Miertus, Lorenzo Lorusso, Gianluca Martino Tartaglia, Munis Dundar, Sandro Michelini, Stephen Thaddeus Connelly, Ariola Bacu, Tommaso Beccari, Ornela Gordani, Xhilda Dhamo, Eglantina Kalluci, Dominika Vešelényiová, Iveta Dirgová Luptáková, Jiri Pospíchal, Matteo Bertelli

Research Outputs: 2025-Present

The integration of advanced artificial intelligence (AI) and humanoid robotics into healthcare represents a critical evolution in biotechnology with profound societal implications. This review explores the bioethical implications of these technologies, and their potential to displace human agency in life-critical decisions. It adopts an interdisciplinary approach encompassing ethics, law, and technology. The review examines how innovations in AI and robotics might shift autonomy from humans to machines, and addresses the accountability challenges inherent in such transitions. We synthesize discussions on the ethical management of AI and robotics, underscoring the importance of maintaining human oversight and integrating ethical standards in technology …

Grokformer: Graph Fourier Kolmogorov‑Arnold Transformers, Guoguo Ai, Guansong Pang, Hezhe Qiao, Yuan Gao, Hui Yan

Research Collection School Of Computing and Information Systems

Graph Transformers (GTs) have demonstrated remarkable performance in graph representation learning over popular graph neural networks (GNNs). However, self-attention, the core module of GTs, preserves only low-frequency signals in graph features, leading to ineffectiveness in capturing other important signals like high-frequency ones. Some recent GT models help alleviate this issue, but their flexibility and expressiveness are still limited since the filters they learn are fixed on predefined graph spectrum or spectral order. To tackle this challenge, we propose a Graph Fourier Kolmogorov-Arnold Transformer (GrokFormer), a novel GT model that learns highly expressive spectral filters with adaptive graph spectrum and spectral …

Cracking Aegis: An Adversarial Llm-Based Game For Raising Awareness Of Vulnerabilities In Privacy Protection, Jiaying Fu, Yiyang Lu, Zehua Yang, Fiona Fui-Hoon Nah, Ray Lc

Research Collection School Of Computing and Information Systems

Traditional methods for raising awareness of privacy protection often fail to engage users or provide hands-on insights into how privacy vulnerabilities are exploited. To address this, we incorporate an adversarial mechanic in the design of the dialogue-based serious game Cracking Aegis. Leveraging LLMs to simulate natural interactions, the game challenges players to impersonate characters and extract sensitive information from an AI agent, Aegis. A user study (n=22) revealed that players employed diverse deceptive linguistic strategies, including storytelling and emotional rapport, to manipulate Aegis. After playing, players reported connecting in-game scenarios with real-world privacy vulnerabilities, such as phishing and impersonation, and …

Level Of Awareness About Diabetic Retinopathy And Eye Checkup Practice Among Type 2 Diabetic Patients Attending Baghdad Teaching Hospital 2023., Ali Olaiwei, Mohammed Ibrahim

Iraqi Postgraduate Medical Journal

Background: Diabetic retinopathy is a common and serious complication of diabetes that can lead to vision loss or even blindness if not detected and treated early. However, some people may not have any symptoms until the condition is advanced. Therefore, regular eye exams with dilated pupils are recommended for people with diabetes to check for signs of diabetic retinopathy and other eye problems regardless of the symptoms.Objectives of the study: To measure patients’ awareness and practices regarding diabetic retinopathy, to detect the barriers for eye screening and receiving eye check-up, and to find if there is any association between level …

Effect Of Ramadan Fasting On Lipid Profile And Bmi Among A Group Of Healthy Adult People In Mosul City/ Iraq, Safana Mohammed, Manal Rasheed

Iraqi Postgraduate Medical Journal

Background :- There is increasing interest regarding the health implications of Ramadan fasting in the recent years. Many reports indicate that fasting during the holy month of Ramadan results in reduced body weight and improved metabolic parameters like lipid profile in healthy individuals . Aim of the study :- To study the effect of fasting during the holy month of Ramadan on serum lipid profile and BMI in healthy adult volunteers. Subjects and methods :- prospective cohort study was done including a total of 50 healthy volunteers. Venous blood samples were taken from volunteer, 1week before Ramadan, and , in …

The Immunological Benefits Of Breast Feeding (Review Article), Ahmed Al-Harbi, Asmaa Shetawi

Iraqi Postgraduate Medical Journal

Breast feeding (BF) provides infants with the most suitable nutrients from birth tell weaning. The major part of mother breast milk (MBM) is water in which the other components dissolve. These components include nutrients and immune factors. The concentration of these components varies by time after delivery. Breast milk even provides infants with various types of bacterial species that contribute for development of infant microbiota.Components that are regarded important for shaping of infant immune response include different factors. MBM contains oligosaccharides which are associated with guts defenses, cytokines that participate in inflammation and immune cells activation, immunoglobulins that arm infant’s …

Hypothyroidism And The Risk Of Occurrence Of Type 2 Diabetes Mellitus, Farha Rasheed, Basil Saleh

Iraqi Postgraduate Medical Journal

Abstract:Background:Hypothyroidism is a syndrome resulting from deficiency of thyroid hormones leading to general slowdown of many metabolic processesObjectives:This study was designed for investigating the occurrence of type 2 diabetes mellitus among sample of patients with hypothyroidism, as well as Investigate the relationship between fasting serum glucose and glycated hemoglobin levels with thyroid stimulating hormone, free triiodothyronine and free thyroxine Patients and Methods:This is a comparative cross section study include 80 subjects was taken, 40 of them as patients diagnosed with clinical hypothyroidism who are on treatment. The remaining 40 apparently healthy individuals who served as a control group. The diagnosis …

Examination Of An Experimental Paradigm Of Impaired Control Over Alcohol Use, Emily K. Junkin

Psychology Theses & Dissertations

Alcohol use disorders peak during young adulthood with nearly 27% of individuals aged 18 to 30 meeting diagnostic criteria. Impaired control, or difficulty limiting alcohol use, has been identified as one of the earliest symptoms of an alcohol use disorder and is predictive of alcohol use severity. Despite the relevance of impaired control for identifying and preventing hazardous drinking behaviors, there is a dearth of research that exists on this critical risk factor. The current study tested an experimental paradigm of impaired control whereby participants self-administered alcohol following guidelines to limit consumption to a low level. It was hypothesized that …

Ms4 Swmpp 2025, National Technology & Engineering Solutions Of Sandia, Llc (Ntess) And Department Of Energy (Doe)

Municipal Separate Storm Sewer System (MS4) Permit

Stormwater discharges from Sandia National Laboratories/New Mexico (SNL/NM) are eligible for coverage under the National Pollutant Discharge Elimination System (NPDES) Municipal Separate Storm Sewer System (MS4) Permit. This Stormwater Management Plan (SWMP) was prepared by National Technology and Engineering Solutions of Sandia (NTESS) for the Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia Field Office (SFO), owner of SNL/NM, located in Albuquerque, NM.

Electronic Resources Updates - 2025 Q2, Brigitte Galauner, Gregg Harris

Electronic Resources Quarterly Updates

No abstract provided.

Germination Time: Impact On Nutritional, Thermal, And Paste Properties Of Red Rice, Thauana Heberie, Lucas Avila Do Nascimento, Ya-Jane Wang, Rosana Colussi, Jaqueline Ferreira De Souza, Andre Ricardo Fajardo, Marcia Foster Mesko

Food Science Faculty Publications and Presentations

BACKGROUNDThe study investigates how varying germination times affect the nutritional, thermal, and pasting properties of red rice. Germination was conducted over 32 h, with aliquots collected every 2 h starting from 18 h for property evaluation.RESULTSAt all evaluated germination times, the red rice samples exhibited low to intermediate amylose levels, while resistant starch content remained relatively constant (approximately 15-20%). Structural changes in the starch were observed: the peak viscosity decreased, maximum gelatinization of the granules occurred at 76 degrees C, and spectroscopic bands characteristic of this polysaccharide were detected at 3400 cm-1 (O-H stretching) and within the 1150-1000 cm-1 range …

Dynamic Few-Shot Prompting For Clinical Note Section Classification Using Lightweight, Open-Source Large Language Models, Kurt Miller, Steven Bedrick, Qiuhao Lu, Andrew Wen, William Hersh, Kirk Roberts, Hongfang Liu

Faculty, Staff and Student Publications

Objective: Unlocking clinical information embedded in clinical notes has been hindered to a significant degree by domain-specific and context-sensitive language. Identification of note sections and structural document elements has been shown to improve information extraction and dependent downstream clinical natural language processing (NLP) tasks and applications. This study investigates the viability of a dynamic example selection prompting method to section classification using lightweight, open-source large language models (LLMs) as a practical solution for real-world healthcare clinical NLP systems.

Materials and methods: We develop a dynamic few-shot prompting approach to classifying sections where section samples are first embedded using a transformer-based …

Cdemapper: Enhancing National Institutes Of Health Common Data Element Use With Large Language Models, Yan Wang, Jimin Huang, Huan He, Vincent Zhang, Yujia Zhou, Xubing Hao, Pritham Ram, Lingfei Qian, Qianqian Xie, Ruey-Ling Weng, Fongci Lin, Yan Hu, Licong Cui, Xiaoqian Jiang, Hua Xu, Na Hong

Faculty, Staff and Student Publications

Objective: Common Data Elements (CDEs) standardize data collection and sharing across studies, enhancing data interoperability and improving research reproducibility. However, implementing CDEs presents challenges due to the broad range and variety of data elements. This study aims to develop a CDE mapping tool to bridge the gap between local data elements and National Institutes of Health (NIH) CDEs.

Methods: We propose CDEMapper, a large language model (LLM)-powered mapping tool designed to assist in mapping local data elements to NIH CDEs. CDEMapper has 3 core modules: (1) CDE indexing and embeddings. NIH CDEs were indexed and embedded to support semantic search; …

Evaluating Large Language Model Performance To Support The Diagnosis And Management Of Patients With Primary Immune Disorders, Nicholas L Rider, Yingya Li, Aaron T Chin, Daniel V Digiacomo, Cullen Dutmer, Jocelyn R Farmer, Kirk Roberts, Guergana Savova, Mei-Sing Ong

Faculty, Staff and Student Publications

Background: Generative artificial intelligence (GAI) is transforming health care in a variety of ways; however, the present utility of GAI for supporting clinicians who treat rare disease such as primary immune disorders (PIs) is not well studied. We evaluated the ability of 6 state-of-the-art large language models (LLMs) for providing clinical guidance about PIs.

Objective: To quantitatively and qualitatively measure the utility of current, open-source LLMs for diagnosing and providing helpful clinical decision support about PIs.

Methods: Five expert clinical immunologists each provided 5 real-world, anonymized PI case vignettes via multi-turn prompting to 6 LLMs (OpenAI GPT-4o, Llama-3.1-8B-Instruct, Llama-3.1-70B-Instruct, Mistral-7B-Instruct-v0.3, …

Impact Of The Adjunctive Use Of Omega-3 In Periodontitispatients With Diabetes On Local And Systemic Chemerin Levels:A Randomized Clinical Trial, Dalia Ghalwash, Ahmed M. Ammar, Ayman El-Gawish, Ahmed Hamdy

Dentistry

Aims: The present study aspired to evaluate the impact of the adjunctive use of omega-3 with nonsurgical periodontal therapy onclinical parameters as well as local and systemic chemerin levels as a marker of cardiovascular disease risk in periodontitis patientswith diabetes.Methods: This randomized clinical trial was performed on thirty periodontitis patients with type II diabetes divided into two equalgroups, both treated by nonsurgical periodontal treatment with the adjunctive use of daily 1000 mg Omega-3FAs in group I onlyfor 6 months. Patients were reexamined after 2 weeks (baseline), 3, and 6 months for recording the clinical parameters as follows:plaque index (PI), gingival …

An Approach To Neutrosophic Hyper Soft Rough Matrix And Its Application, J. Boobalan, E. Mathivadhana

Neutrosophic Sets and Systems

No abstract provided.

An Application Of Site Selection For Solid Waste Management System Using Neutrosophic Set, A. Savitha Mary, D. Sarukasan, C. Kayelvizhi, L. Jethruth Emelda Mary, F. Josephine Daisy, K. Pitchaimani

Neutrosophic Sets and Systems

No abstract provided.