Digital Commons Network^™

Ion Channel Gating Probability Of Voltage-Gated Hnav1.1: Role Of Beta Subunits And The Associated Impacts On Epilepsy, Georgia Blue Hill, Soha Haniyyah, Diana M. Cortez, James R. Groome

Idaho Conference on Undergraduate Research

Voltage-gated sodium channels are essential for initiating action potentials in neurons. Mutations in the human brain sodium channel hNaV1.1 ion channel are associated with a large number of neurological disorders, such as epilepsy. Despite its clinical relevance, there is still much to characterize about the specific effects of how these mutations affect sodium channel behaviour, including the role of the smaller beta subunits. To investigate this, hNaV1.1 channels were expressed with varying beta subunits (beta 1,beta 2, or none) in Xenopus oocytes. Electrophysiology was utilized to record sodium currents and measure the probability of sodium channels activating (open state) or …

Sidesense: Robust Physiological Motion Detection Via Mmwave Joint Communication And Sensing Systems With Multiple Beams, Mohammed Shadman Ishrak, Jannatun Noor Sameera, Alvin Yang, Yanjun Pan, Yao Zheng, Olga Boric-Lubecke, Victor M. Lubecke

Electrical Engineering and Computer Science Faculty Publications and Presentations

A 28-GHz multibeam joint communication and sensing system called SideSense is presented, in which a line-of-sight (LoS) beam is used to maintain reliable communication, while other sensing beams are used to enhance physiological motion detection. SideSense decodes the motion frequency and shape from the channel state information (CSI) by first tuning the gain ratio and phase differences between the LoS communication beam and non-LoS (NLoS) beam to maximize the sensing signal-to-noise ratio (SSNR) without significantly degrading the communication channel capacity (CCC). Analytical results based on a bistatic model are presented to show a gain ratio of around 1 and a …

Ipm South Africa, Npc: Pioneering Hiv Prevention Options For Women, Ipm South Africa

Dapivirine Vaginal Ring (PrEP Ring)

The Population Council is leveraging its innovative ring technology to develop a range of next-generation prevention products that advance the science of HIV prevention. These include a three-month dapivirine-only vaginal ring as well as combination rings that leverage the potency of different ARVs.

There will be no single solution to ending the epidemic—stopping HIV will require a variety of options. Research from the family planning field has shown that when more options are available, women are able to choose what best fits their circumstance and life stage. This means that there is an urgent need to expand the number of …

Full Issue - Spring 2025 - Volume 112, Issue 1, Colby College

Colby Magazine

04. Planting Seeds to Grow a Stronger Community
16. Retiring Provost McFadden: Colby’s ‘Special Sauce’ is What Makes it Great
24. Pulver Scholars Explore Scientific Possibility
32. A Warm Wilderness Welcome for New Colby Students
42. Dare Northward is Shaping Colby as a Global Leader
48. Bringing Them All Back Home

Alfred Russel Wallace Notes 37. What About Wallace On Vaccination . . . ?, Charles H. Smith

Faculty/Staff Personal Papers

Best known for his natural history studies on evolution and biogeography, Alfred Russel Wallace (1823−1913) had a significant second career as a social critic. One of his most controversial stances was his position on (smallpox) vaccination. Anti-vaxxers of the present frequently bring up his name as a resource for their side, but the situation is not so easily reducible to that.

Nsu Kpcom Link - Summer 2025 - Volume 4.2, Nova Southeastern University

NSU Florida Link Newsletter

No abstract provided.

Freeman Honors – The Annual Newsletter: Fall 2024-Spring 2025, Texas Southern University, Thomas F. Freeman Honors College

Honor's College Newsletters

Annual 2024-2025 Newsletter

A Link Prediction Model For Knowledge Graph Completion Of Traditional Chinese Medicine Cases, Qifeng Lou, Dongmei Mu, Shutong Wang, Lili Huang

Journal of Scientific Information Research

[Purpose/significance] To propose a link prediction model for completing the knowledge graph of Chinese medicine cases, aiming to fill in the missing information in the knowledge graph,reveal the potential unknown associations,and promote the construction of a more comprehensive and detailed knowledge graph of Chinese medicine cases.

[Method/process] Medical cases in the field of TCM asthma were collected and integrated to construct a knowledge graph of TCM asthma diagnosis and treatment. By introducing Dropout regularization and Batch Normalization techniques into the RotatE model, an improved ERDBN model is proposed and applied to the task of refining the asthma diagnosis and treatment …

Differential Privacy Enabled Deep Skin Image Classification Model Development, Prasun Kumar Mandal

Master’s Dissertations

Abstract In the era of big data, the explosive growth in data volume has significantly accelerated the development of deep learning. Deep learning is the most promising area of AI, yielding significant advancements in medical image classification. However, healthcare data contains important sensitive information and so privacy and security are crucial to preventing unauthorized access. Note that there are several data protection rules from multiple regulations to penalize any kind of data security violation, for example, the data protection principles (Article 5.1-2) and the data protection by design and by default (Article 25) of the General Data Protection Regulation from …

Transcripts With High Distal Heritability Mediate Genetic Effects On Complex Metabolic Traits., Anna L. Tyler, J Matthew Mahoney, Mark P Keller, Candice N Baker, Margaret Gaca, Anuj Srivastava, Isabela Gerdes Gyuricza, Madeleine J Braun, Nadia Rosenthal, Alan D Attie, Gary Churchill, Gregory W. Carter

Faculty Research 2025

Although many genes are subject to local regulation, recent evidence suggests that complex distal regulation may be more important in mediating phenotypic variability. To assess the role of distal gene regulation in complex traits, we combine multi-tissue transcriptomes with physiological outcomes to model diet-induced obesity and metabolic disease in a population of Diversity Outbred mice. Using a novel high-dimensional mediation analysis, we identify a composite transcriptome signature that summarizes genetic effects on gene expression and explains 30% of the variation across all metabolic traits. The signature is heritable, interpretable in biological terms, and predicts obesity status from gene expression in …

Undergraduate And Graduate Course Descriptions, Summer 2025, Wright State University

Course Descriptions

Wright State University undergraduate and graduate course descriptions from Summer 2025

Summer 2025, Echoes Staff

Rose Echoes

No abstract provided.

Utilizing Pharmacogenomics To Improve Students' Self-Perception On The Interprofessional Competencies Of Roles And Responsibilities, And Teams And Teamwork, Amanda Brown, Moom R. Roosan, Robert Goldsteen, Scott D. Ochs, Reza Taheri

Pharmacy Faculty Articles and Research

Introduction

Pharmacogenomics (PGx) is an emerging discipline with the potential to revolutionize personalized medicine, but its successful implementation requires interprofessional collaboration. To address this need, a virtual interprofessional education (IPE) session was designed for student pharmacists and medical students to engage in a case-based learning experience.

Objective

The primary objective was to develop and implement an IPE activity focused on a patient case requiring PGx-guided dual antiplatelet therapy and to assess students' perceptions of two Interprofessional Education Collaborative (IPEC) Version 3 Core Competencies. A secondary objective was to identify key lessons from the session.

Methods

Pharmacist and physician faculty collaboratively …

Examining Coping, Individual Resilience, And Family Resilience As Strengths-Based Factors For Lgbtq+ Individuals, Elizabeth Moriarty Combs

Theses and Dissertations

Lesbian, Gay, Bisexual, Transgender, Queer/Questioning, and More (LGBTQ+) individuals are part of a diverse and complex community that has unique considerations regarding physical and mental health. While there is ongoing health equity research regarding LGBTQ+ individuals, the focus is often on health disparities. A strengths-based approach to helping LGBTQ+ individuals through research and other avenues may be beneficial. This multi-manuscript dissertation includes two studies that explored the current literature on strengths-based factors such as coping, individual resilience, and family resilience within LGBTQ+ individuals, as well as determined the feasibility of utilizing these factors to assist LGBTQ+ individuals with health and …

Non-Traditional Socio-Environmental And Geospatial Determinants Of Alzheimer's Disease-Related Dementia Mortality, Skanda Moorthy, Jean-Eudes Dazard, Zhuo Chen, Shruthika Palanivel, Salil Deo, Sanjay Rajagopalan

Student Scholarship

Importance: Recent data point to the impact of non-traditional environmental and social factors on Alzheimer's Disease-Related Dementias (ADRD) mortality. Our study aimed to determine the extent to which antecedent air pollution, social vulnerability, and geospatial features in the environment associate with ADRD mortality. Design: This was a cross-sectional study conducted across the mainland United States. County level Social Vulnerability Index (SVI), particulate matter air pollution (PM2.5) were linked to ADRD mortality. Patient Rule Induction Method (PRIM) was used for delineating and characterizing “bumps” or spikes in mortality. SHapley Additive exPlanations (SHAP) values were used to rank variables by predictivity and …

Vitamin D Status And Risk For Breast Cancer In Kenya, Ronald Wasike, Victor Mobegi, Esther Maina, Francis Makokha, Robert Armstrong, Annastacia Mbithi

General Surgery, East Africa

Background: Vitamin D plays a critical role in bone metabolism, calcium regulation, and various cellular processes, including those linked to cancer. The biologically active form, 1,25-dihydroxyvitamin D [1,25(OH)2D], works through the Vitamin D Receptor (VDR). Polymorphisms in VDR and related genes have been associated with cancer risk, including breast cancer. This case-control study aimed to investigate the relationship between serum vitamin D levels and breast cancer among Kenyan women.

Methods: Serum 25-hydroxyvitamin D [25(OH)D] levels were measured in 112 breast cancer patients and 106 controls using electrochemiluminescence.

Results: Results indicated that 81.2% of participants had deficient or insufficient vitamin D …

Clinical Trials Unit Newsletter - Issue 02, Clinical Trials Unit (Ctu)

Clinical Trials Unit (CTU) Archives

• What's inside this issue:
• The Clinical Trials Summit of Pakistan 2025
• Biosimilar trials at CTU!
• Completion of the Panbio Self-Test Enrolment
• Coming Together for Better Cancer Care
• Informative Snippets
• Clinical Trials Unit celebrates Clinical Trials Day
• Happenings!
• Achievements
• Trials Recruiting Now
• Trials Completed
• Publications
• Upcoming Events

Library News July 2025, Research Medical Library

Library News 2025

• What's New with Journal Impact Factors?
• Five Tips for Productive Writing from Faculty Members
• LibKey Nomad Now Integrated with Cabell's Predatory Reports
• On "Metastasis," "Metastases," and "Metastasize"

2025-2026 Fordham Law School Faculty Bibliography, Fordham Law School

Faculty Bibliography

Bibliography of Fordham Law School faculty publications in print from July 2025-June 2026.

Unmanned Aerial Systems (Uass) In Rangeland Ecosystem Management: Assessing Grazing Impacts At Willits, California, Pramil Khanal

Master's Theses

California's rangelands, vital for biodiversity and cattle production, face threats from land use changes and climate changes, necessitating robust management strategies. While overgrazing has been studied extensively, the effects of light rotational grazing on vegetation have seldom been assessed. This study used Unmanned Aerial Systems (UASs) and multispectral imagery to assess the seasonal impacts of light rotational grazing on vegetation health and coverage in wetland mitigation areas near Willits, California. Data were collected in May (spring) and November (fall) 2024 using a DJI M3M drone and MicaSense camera capturing RGB and Near-Infrared (NIR) bands. Green Chromatic Coordinate (GCC) and Normalized …

Mental Health, Racism, And Contemporary Challenges Of Being Black In America, Michael Mcclam

Staff and Researcher Publications

No abstract provided.

Scientific Note: Garden Loosestrife (Lysimachia Vulgaris, Primulaceae), An Emerging Invasive Plant Species Of Riparian Corridors In The Mid-Atlantic Region, Christopher T. Martine, Amy L. Jewitt, Claire M. Ciafre, Kaitlin G. Henry, Elizabeth H. Williams, Pj Newhart, Melody P. Sain

Faculty Journal Articles

Lysimachia vulgaris (garden loosestrife, Primulaceae) is an herbaceous perennial native to Europe that has been identified as an aggressive invasive species in parts of North America. The status of the species in the Mid-Atlantic region of the US, however, is poorly determined. Using recent field observations (from iNaturalist, iMapInvasives, and EDDMapS records) we here report localized incursions of L. vulgaris in the Susquehanna River Valley of central Pennsylvania, along with notes on its ecology, threats to native plant communities, and broader distribution in the state.

Against The Phrase "Aggressive Care", Trevor M Bibler

Center for Medical Ethics and Health Policy Staff Publications

Language is the primary technology clinical ethicists use as they offer guidance about norms. Like any other piece of technology, to use the technology well requires attention, intention, skill, and knowledge. Word choice becomes a matter of professional practice. The Brief Report offers clinical ethicists several reasons for rejecting the phrase "aggressive care." Instead, ethicists should consider replacing "aggressive care" with the adjacent concept of a "recovery-focused path." The virtues of this neologism include: the opportunity to set aside the emotion of "aggression," the phrase's accuracy when capturing the intention of the patient or their representative, and an unappreciated rhetorical …

Full Issue, Vol. 16

Monographs of the Western North American Naturalist

No abstract provided.

Uni Impact: Faculty/Staff Scholarly Publications And Featured Awards Newsletter, V3i1, 2024, Rod Library. Research & Sponsored Programs. Uni Foundation. University Of Northern Iowa.

UNI Impact: Faculty/Staff Scholarly Publications and Featured Awards Newsletter

Highlights the scholarship, research, and other scholarly work produced by University of Northern Iowa faculty, students, and staff.

This issue covers the period of January - June 2024.

Swosu Fact Book Summer 2025, Joel Harrel Kendall, Diane Fitzsimmons, Kelsi Burghardt

Fact Books

The 2nd annual Southwestern Oklahoma State University Summer Fact Book provides a ready source of information to answer frequently asked questions about the University and its operations. The Summer Fact Book is compiled annually by the Office of lnstitutional Research to assist the university with strategic planning, academic program reviews, grant writing, accreditation, and institutional information to help guide decision-making. The report uses data collected from 2016 to 2025 and is designed to help faculty, staff, administrators, and external stakeholders better understand the student body and university trends.

Bibliometric Analysis Of Congenital Toxoplasmosis: A Ten-Year (2013-2023) Review Of Research Publications, Festus Mulakoli, Horatius Musembi, Ann Kimani

School of Nursing & Midwifery, East Africa

Background:Toxoplasma gondii, an obligate intracellular protozoan, infects more than one-third of the global population and causes toxoplasmosis, which can lead to severe fetal complications in pregnant women. The global prevalence of latent toxoplasmosis in pregnant women is 33.8%, with regional variations and risk factors, including the consumption of undercooked meat, exposure to cat feces, and consumption of contaminated water. Pregnant women lack sufficient awareness of these risk factors, necessitating enhanced education, regular screening, and counseling during antenatal care for early detection and management.

Aim: This study performed a comprehensive bibliometric analysis of research on congenital toxoplasmosis published between 2013 …

A Wearable-Based Approach To Spinal Posture Tracking And Assessment, Sydney Marie Sherman, Noah Jeffery

Biomedical Engineering: Graduate Reports and Projects

This paper describes the design, manufacturing, and testing of a novel spinal posture tracking wearable device with embedded sensors. Currently on the market, most of the spinal posture tracking devices only focus on one segment of the spine and therefore do not track the entirety of human posture. The objective for this project was to create a wearable device in the form of a “smart shirt” that offers insights into posture trends throughout the day by tracking the entire spine. To begin the project, multiple designs were developed for the sensor array and wearable materials. These concepts were compared against …

The Homo Economicus Model Of Work Describes Men More Than Women, But Only In Weird Cultures, Thomas Talhelm, Danila Medvedev, Yin Li

Minnesota Journal of Law & Inequality

No abstract provided.

Un(Der)Explored Links Between Plant Diversity And Particulate And Mineral-Associated Organic Matter In Soil, Šárka Angst, Gerrit Angst, Kevin E. Mueller, Markus Lange, Nico Eisenhauer

Biological, Geological, and Environmental Faculty Publications

Plant diversity can alter soil carbon stocks, but the effects are difficult to predict due to the multitude of mechanisms involved. We propose that these mechanisms and their outcomes can be better understood by testing how plant diversity affects particulate organic matter (POM) and mineral-associated organic matter (MAOM) depending on whether MAOM storage is "saturated" and the total soil organic matter pool is limited by plant inputs. Such context-dependency of plant-diversity effects on POM, MAOM, and total soil organic matter helps explain inconsistencies in plant-diversity-soil-carbon relationships across studies. Further illumination of this context-dependency is required to better predict consequences of …