Digital Commons Network^™

Plastic Purgatory: Investigating The Effects Of Plastic Litter On Water And Organic Content In Topsoil In Holland, Michigan, Kamryn Bice, Annis Cairns, Maddie Devries, Sebastian Lema

25th Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2026)

Plastic accumulation in soils can offer important insights into how human activity affects terrestrial ecosystems. In this study, we examined the relationship between plastic litter and soil quality at several sites across Holland, Michigan to determine whether plastic abundance was associated with changes in soil properties. Soil samples from five different site types – construction, residential, commercial, nature, and a control – were collected over a threeweek period, then analyzed for pH, water contents, total organic carbon (TOC), and plastic abundance through field testing and laboratory methods. The number of plastic pieces ranged from 0 to 27 with the largest …

Post-Operative Delirium: A Neurocognitive Syndrome Expressed Through An Interactive Website Module Of Animations, Bailey Mikytuck

Theses

Post-operative delirium (POD) is a neurocognitive complication that can arise in patients who have undergone a surgical procedure. It is characterized by the onset of reduced attention or cognition, mood or personality disturbances, and hallucinations that occur between 10 minutes to multiple days after waking up from anesthesia. These symptoms may only be brief, but in some cases can lead to long-term cognitive impairment and dysfunction and have been associated with the development of dementias. It is estimated that rates of POD occurrence are between 13.2- 41.7% with major risk factors including being over the age of 65 and the …

Unraveling The Role Of The C-Terminal Intrinsically Disordered Linker In The Bacterial Cell Division Protein Ftsz, Jessica Louise Bullock

Arts & Sciences Graduate Student Theses and Dissertations

FtsZ is a highly conserved cytoskeletal protein that is essential for organizing the cell division machinery in bacteria. The first observable step in cytokinesis, FtsZ forms a ring at the future division site. The FtsZ ring serves as a platform for recruitment of other division proteins. FtsZ has three major domains: a tubulin-like GTP binding core domain, an intrinsically disordered C-terminal linker (CTL), and a conserved ~11-residue motif known as the C-terminal peptide (CTP). The core domain is sufficient for head-to tail assembly of FtsZ polymers in vitro. The CTP interacts with modulatory proteins to coordinate division, while the CTL …

Nutrition Strategies To Help Children With Arfid Overcome Nutrition-Related Deficiencies, Saul Campos

The Agora

Avoidant/Restrictive Food Intake Disorder (ARFID) is a serious and relatively newly recognized eating disorder that affects children and adolescents. The disorder was formally introduced in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and is characterized by restrictive eating patterns that lead to significant nutritional deficiencies, weight loss or poor growth, dependence on nutritional supplements, or interference with psychosocial functioning (American Psychiatric Association, 2013). Current estimates suggest that ARFID may affect approximately 1–5% of children and adolescents, though prevalence varies depending on the population studied and diagnostic criteria used (Białek-Dratwa et al., 2022). Unlike other eating disorders, …

The Genetics Of Sex, Fortis Brown

The Agora

Sex is a complex biological process that begins in the womb and lasts into puberty and beyond. It is often presented to society as a binary, chromosome-based system where XX means female and XY means male. In reality, chromosomes are just the beginning of a lifelong process involving hormones that influence biological changes. This process becomes apparent with its errors, known as Differences in Sexual Development (DSDs). DSDs can be caused in two main ways: through changes in either meiosis or in gene expression. While many consider these changes as ‘errors’, the processes that cause them to have been intentionally …

A Computer Vision Approach To Analyzing Taxane Effects On Prostate Cancer Cells, Diana Elizabeth Dancea

Electronic Theses and Dissertations 2020 - Present

Actin is a family of proteins that help create the structure of the cytoskeleton, which gives shape to the cell. In many chemotherapy treatments, researchers target actin because it controls the cell division process. Therefore, if they are able to understand the actin fibers, that may help in formulating methods to stop or slow down cancer cells from reproducing. Another important protein is PAK6, which regulates actin. In our research, a collaborative effort with Prof. Michael Lu’s lab at Florida Atlantic University, we use machine learning techniques to analyze cells which had their PAK6 protein knocked out, and compare them …

The Fungus Among Us: Latency, Reactivation, And The Expanding Clinical Spectrum Of Coccidioidomycosis, Sumeet Bhardwaj, Arushi Tewari, Rishima Tewari, Simona Kogan

Student Publications

Coccidioidomycosis is a serious fungal infection that can produce a wide range of clinical manifestations, from mild, self-limiting pulmonary disease to severe, disseminated infection that can involve nearly any organ system, including the skin. Coccidioidomycosis may also affect patients at the psychiatric level. Its clinical relevance has increased markedly in recent years, as incidence continues to climb, geographic distribution widens, and emerging presentations challenge traditional assumptions regarding fungal latency and host immunity. A notably important and developing area of study is the concept of late reactivation. A narrative review of the literature was conducted using PubMed, MEDLINE, and Google Scholar. …

An Emerging Approach To Ibd Treatment: Personalized Nutrition Through Gut Microbiome Optimization., Kafayat Yusuf, Thomas M. Attard, Mazin Al-Kasspooles, Shahid Umar

Manuscripts, Articles, Book Chapters and Other Papers

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract characterized by relapsing and remitting disease activity. Despite decades of research, a definitive cure for IBD remains elusive, as cycles of remission and flare-ups mark the disease course and often relies on long-term pharmacologic and supportive strategies. Increasing evidence indicates that diet and nutrition play an important role in modulating the outcomes of IBD. Although a wide range of dietary interventions has been explored, no universally effective approach has been established. Investigations have also proven that different dietary interventions can significantly affect clinical outcomes by altering gut …

Developmental Underpinnings Of The Other Race Effect Using Fmri, Aquilla Denise Copeland

Electronic Theses and Dissertations 2020 - Present

It is well established that perceptual experience with own-race faces is associated with faster and more accurate recognition of own-race compared to other-race faces — a phenomenon known as the other-race effect (ORE). Previous fMRI research has shown that adults generally exhibit more robust face-sensitive responses than children in the core face-processing areas, especially to own-race versus other-race faces. Although much is known about the neural underpinnings of the ORE in adults, little is known about this phenomenon in children. The present experiment aimed to examine face-sensitive fusiform and occipital regions in 8- to 10-year-olds and adults as they engaged …

Conserved Post-Odor Dynamics In The Olfactory Systems Of Mice And Locusts, Feiyang Deng, Ryan Kroeger, Jacob Reimer, Baranidharan Raman, Benjamin R Arenkiel

Faculty, Staff and Students Publications

Interpreting chemical information and translating it into ethologically relevant output is a shared challenge of olfactory systems across species, but are olfactory computations conserved across species to overcome these common challenges? To investigate this, we compared neural activity in the locust antennal lobe (AL) and mouse olfactory bulb (OB) both during and after odor presentations. We found that odors activated nearly mutually exclusive neural ensembles during odor presentations ("ON response") and after the termination of the odor stimulus ("OFF response"). ON and OFF responses evoked by a single odor were anticorrelated with each other. Inverted OFF responses persisted long after …

Identification Of Sex Chromosomes In The Genus Lepidodactylus, Zuleihat Yusuf Idris

Master's Theses (2009 -)

ABSTRACT IDENTIFICATION OF SEX CHROMOSOMES IN THE GENUS LEPIDODACTYLUS Zuleihat Y. Idris, M.S Marquette University, 2026 Sex determination in vertebrates is remarkably diverse and is characterized by frequent evolutionary transitions between genetic sex determination (GSD) and environmental sex determination (ESD). Within reptiles, geckos (Gekkota) exhibit the most diverse sex determination mechanism in vertebrates. Although geckos are the target of more recent research, most lineages still lack identifiable sex-determining mechanisms. This gap in knowledge has limited the understanding of the diversity and evolution of sex determination in vertebrates. In this study, an automated pipeline (FnPiPER) and whole-genome resequencing from male and …

Development Of Tpack-Based Learning Book To Improve Learning Outcomes Of Third Grade Students Of State Elementary School 16 Banda Aceh, Nurul Zikri Filina, Siti Mayang Sari, Zahraini Zahraini, Jiyeon Na

Jurnal Pendidikan Humaniora

This research aims to develop a TPACK-based Basic Science learning book as an effort to improve the learning outcomes of class III students at State Elementary School 16 Banda Aceh. This research is a type of research and development (R&D), using the ADDIE method (Analysis, Design, Development, Implementation, Evaluation). The research results prove that the TPACK-based Basic Science learning book is suitable for use with media expert validation results in the very good category (93%), material expert validation in the very good category (94%), language experts showing the very good category (90%). The TPACK-based Basic Science Book can improve the …

Potential Applications Of Thymus Vulgaris In Dental Care: A Review Of Antimicrobial And Oral Health Benefits, Lakenzia Z. Ham

Undergraduate Research Conference

This research proposal focuses on how common thyme (Thymus vulgaris) can be used in dental care. There has been more interest in natural products for dental health because some common dental treatments can have side effects or lead to antibiotic resistance. Thyme contains natural compounds like thymol and carvacrol that help kill bacteria, reduce inflammation, and prevent buildup on teeth.

The purpose of this study is to investigate the current scientific literature to see the effectiveness of thyme in preventing common oral health problems like cavities, gum disease, and bad breath. Research shows that thyme can fight bacteria …

From Garden To Laboratory: The Scientific Significance Of Zinnia Elegans, Katelyn G. Klark

Undergraduate Research Conference

Zinnia elegans is a flowering species in the Asteraceae family that originated in Mexico and eventually spread to Europe (Burlec et al., 2019). This species' vast array of colors, drought resistance, and other agricultural benefits make this plant highly sought after in gardens worldwide (Burlec et al., 2019). However, following the methodology of a preliminary research literature review, recent scientific research suggests that Z. elegans may possess significance beyond its aesthetic appeal. This literature review aimed to examine recent scientific findings regarding zinnias and their potential agricultural, medicinal, and genetic applications. To explore these possibilities, recent scientific studies were examined …

Hurc 2025 Program, Russell Keck, Nathaniel Wiewora Ph.D.

Ex Sapientia Loqui

The program for the 2025 session of Harding Undergraduate Research Conference (HURC), sponsored by the Harding Honors College and the Arkansas Eta chapter of Alpha Chi.

Hurc 2021 Program, James Huff

Ex Sapientia Loqui

The program for the 2021 inaugural session of Harding Undergraduate Research Conference (HURC), sponsored by the Harding Honors College and the Arkansas Eta chapter of Alpha Chi.

An Integrative Description Of Euscorpius Diagorasi Sp. N. From Rhodes, Greece (Scorpiones: Euscorpiidae), Konstantinos Kalaentzis, Francesco Frigioni, Eliza Kaitetzidou, Alessio Iannucci, Alexandros Triantafyllidis

Euscorpius

The genus Euscorpius Thorell, 1876 comprises a diverse and taxonomically challenging group of scorpions in the Mediterranean, with Greece representing one of its principal centers of diversity. In this study, we provide an integrative description of Euscorpius diagorasi sp. n., a new species from Rhodes Island, Greece. The new species is described on the basis of adult male and female morphology and mitochondrial COI sequence data. It is a small oligotrichous species characterized by a total length of approximately 21–25 mm, pale yellow to light brown coloration with darker reddish-brown pedipalps, pectinal tooth count of 8 in the male …

Beyond A Shadow Of A Doubt: Examining The Female Gothic In Mary Shelley's Frankenstein And Bram Stoker's Dracula, Delaney Harrington

Ex Sapientia Loqui

This paper establishes characteristics of the Female Gothic subgenre, traces the origin of the fiction subgenre throughout the years, and applies these characteristics to argue that Frankenstein and Dracula should be considered prime examples of feminist literature. I analyse the characters of both novels, as well as the authors' respective intentions and social contexts.

The Short-Term Water Quality Impacts Of The College Lake Low-Head Dam Removal, Lorraine L. Upton

Student Scholar Showcase

Dam removal in the United States has become a common practice for stream restoration and community safety. Studies have shown removals to restore an ecosystem to its natural flow, but in urban environments, dams can serve as a retention basin that helps to mitigate increased amounts of stormwater and high pollution loads from increased percentages of impervious surfaces. A central Virginia watershed located in an urbanized community recently experienced a low-head dam removal and its conversion to a constructed wetland. This study assesses the short-term impacts of the dam removal through water quality sampling based on its chemical, biota, and …

Synthesis And Biological Activity Of Gold(Iii) Complexes With Proline And Fluorinated Proline Ligands, Parker J. Lynch

Student Scholar Showcase

Synthesis and Biological Activity of Gold(III) Complexes with Proline and Fluorinated Proline Ligands

Gold(III) amino acid complexes are an important area of research because metal complexes can provide chemical and biological activity that typical carbon-based drugs cannot. These complexes can form structures that interact with different parts of the cell, such as DNA or proteins, allowing them to disrupt harmful cells. Modifying the ligands in these complexes can improve stability and influence how the metal interacts with biological systems. With growing interest in metal-based anticancer agents, further understanding of gold(III) complexes containing proline-derived ligands is needed. The goal of this …

Late-Season Forb Availability And Bumble Bee Foraging Patterns In Iowa’S Restored Prairies And Suburban Gardens, Isaac De Young, Ellary Carson, Mya Cole, Tucker Draayer, Sharon Huffman, Naomi Johnson, Jasmine Lux, Genesis Maldonado, Caitlin Olson, Maelee Rodenburg, Jordan Shull, Travis Sweeney, Arianna Van Donkelaar, Laurie Furlong, Todd Tracy

Celebration of Research

Pollinators are essential to terrestrial ecosystems, and bumble bees are among the most effective pollinators in the United States (Hatfield et al., 2012). They pollinate forbs (non-grass herbaceous flowering plants), including crops, garden plants, and native prairie species (Dumroese et al., 2016). Their ability to travel long distances, forage in cool temperatures, and buzz-pollinate makes them critical to both wild and agricultural productivity (Mola & Williams et al., 2019). Research shows that bumble bee populations have declined in recent decades due to habitat loss, reduced floral resources, pesticide exposure, and climate change (IPBES, 2016).

Northwest Iowa is dominated by agriculture, …

Bio-Inspired Materials And Metamaterials For Tunable Biomimetic Properties In Diverse Engineering Applications, Sandeep Suresh Babu

Thesis/ Dissertation Defenses

Nature has always played the role of a design cue for several targeted engineering applications, with designers attempting to mimic the characteristics of natural organisms to have significant advantages in the engineering performance cycle. This dissertation explores the relationship between bioinspired design parameters and material compositions in diverse engineering applications, ranging from mechanical energy absorption to tissue engineering applications. A two-fold objective was followed in the study, where the initial focus was based on the structural design of metamaterial lattices based on geometrical cues observed in the horn structure of bighorn sheep and cuttlebone microstructure of cuttlefish. The advances made …

Eagleeye Is Landing: Discovery Of Cytotoxic And Defense Genes In A Cluster A16 Mycobacteriophage, Clara Bader, Kylie Foss, Mallory Gramstad, Korver Hupke, Jenna Kluxdal, Elsie Larson, Ayda Maassen, Adriana Sandbulte, Dane Schoenborn, Emma Steinhardt, Alexa Trover, Sara S. Tolsma

Celebration of Research

EagleEye is a temperate bacteriophage, which was isolated on the host, Mycobacterium smegmatis mc2 155 from soil collected in Houston, TX. It is classified as cluster A16. We are using a systematic genetic screen to uncover functions of phage genes for which the function is unknown. We cloned each gene into the pExTra plasmid and assayed phage gene individually for two phenotypes: cytotoxicity, the ability to interfere with host cell growth, and defense, the ability to protect the host cell from infection by other phages. We have cloned all but 15 of EagleEye’s 95 protein-coding genes. Thus far, we have …

If You Give A Mouse A Phage, Peyton Abraham, Princess Bola-Lawal, Amelia Brown, Anne Eveland, Jenna Kluxdal, Elsie Larson, Gabrielle O'Bannon, Leonardo Romo, Sara S. Tolsma

Celebration of Research

Island3 (Cluster I1) and Sbash (Cluster I2) are Mycobacteriophages that have a high degree of genetic similarity—especially in the region of their genomes that include genes for structural proteins. Because their structural proteins appear so similar, we hypothesized that antibodies raised against Island3 would cross-react with Sbash and vice versa. To test our hypothesis, we immunized female BALB/c mice with phage high titer lysates or filtered M. smegmatis (control), collected serum, and used the antibodies in ELISA and Western Blot assays. We observed less cross-reactivity than we expected.

Annotation Of Bacteriophages Redraider89, Superherocarly, Cherrycola, And Kouch, Brianne Brandt, Mya Cole, Matthew Dawkins, Julia De Vos, Isaac De Young, Hannah Gordon, Landon Greve, Brody Hoverstein, Mia Kellenberger, Genesis Maldonado, Charlotte Pritchard, Noah Robinson, Leonardo Romo, Mackenzie Schram, Grace Timm, Arianna Van Donkelaar, Kamea Van Kalsbeek, Byron Noordewier, Sara S. Tolsma

Celebration of Research

Phages are important research tools and can be used as an alternative to antibiotics. They are abundant and diverse. Genome annotation is used to better understand phage diversity as well as individual phages for use in the lab and clinic. We annotated the genomes of four novel phages: RedRaider89, SuperHeroCarly, Kouch, and CherryCola. All four phages were discovered by Northwestern College students. CherryCola is a Cluster DC1 phage that infects Gordonia terrae. It has 92 predicted protein-coding genes. RedRaider89 (Cluster B1) and SuperHeroCarly (Cluster D1) infect Mycobacterium smegmatis mc²155. RedRaider89 has 99 predicted protein-coding genes and SuperHeroCarly has 87 …

Role Of Dental Screening In Preventing Hip Prosthetic Joint Infections, Aidan Anderson, Cailee Dix, Emma Franken, Erin Keizer, Zavyr Metzger, Tyra Snyder, Pam Hulstein

Celebration of Research

Hip arthroplasty is a common procedure, but Periprosthetic joint infection (PJI) remains a serious postoperative complication associated with increased hospital stays, readmissions, and costs. Evidence suggests that poor oral health may contribute to PJIs through the spread of bacteria from the mouth to the surgical site. This project examined the relationship between preoperative dental health and postoperative outcomes in adults aged 50–90 undergoing hip replacement. A literature review using the Johns Hopkins Research Evidence Appraisal Tool evaluated 19 studies from databases such as PubMed and ScienceDirect. While no clear association was found between specific dental risk factors and PJIs, untreated …

Understanding The Role Of Lipid Metabolism On Pancreatic Cancer Metastasis, Luke Fischer, Kylie Foss, Jacob Lewis, Joshua Lewis, Emma Steinhardt, Megan Vangarven, Cody Rozeveld

Celebration of Research

Pancreatic cancer is one of the deadliest types of cancer due to late-stage detection and early metastasis. Other than smoking, one of the few known risk factors for pancreatic cancer is obesity (1). On the cellular level, excess fat can promote cell migration and invasion (2). However, the exact fat utilization pathway remains unknown. We propose that lysosomes may be exploited in pancreatic cancer to break down fat and provide energy for metastasis and invasion.

Bacterial 2-Hybrid Assay: Interactions Of Phage Island3'S Gene 36 And Mycobacterium Smegmatis Gene Products, Elsie L. Larson, Sara Tolsma

Celebration of Research

Island3 is a Cluster I1 bacteriophage that infects Mycobacterium smegmatis. Northwestern College students are performing systematic genetic screens to identify Island3 genes that are cytotoxic or protect host cells from infection by other phages (defense). We identified Island3’s gp36 as a cytotoxic gene. Now we are using a bacterial two-hybrid assay to identify a host protein(s) interaction partner. We hypothesize that host proteins that bind gp36 will reveal the mechanism by which gp36 confers cytotoxicity.

Investigation Of Northwest Iowa Pollinator Communities Using Two Survey Methods, Ellary Carson, Mya Cole, Isaac De Young, Sharon Huffman, Naomi Johnson, Genesis Maldonado, Maelee Rodenburg, Travis Sweeney, Tark Griebel, Laurie Furlong, Todd Tracy

Celebration of Research

The ecological services of insect pollinators are well established and the documented decline in pollinator biodiversity is of great concern. Baseline data and continued monitoring are essential as we ongoing trends in pollinator communities and evaluate efforts supporting their recovery. Using two survey methods, our study provides pollinator community data at two conservation sites in Northwest Iowa. In September of 2025, we used three colors of pan traps (blue, yellow, and white) to investigate pollinator communities at a small, reconstructed prairie (Buena Vista County Park) and a nearby partially restored native prairie (The Nature Conservancy Glacial Hills Preserve). We also …

Geographic Trends In North American Tornado Risk: A 75 Year Analysis, Thomas Tracy, Todd Tracy

Celebration of Research

In recent years, many meteorologists have claimed that ‘tornado alley’ has shifted over the last decades toward the east. We wanted to see if this claim holds true. We searched online for databases containing information on all US and all Canada tornadoes. By visualizing the data, we were able to find some trends in rating and the number of tornadoes over time. Using a program we wrote in R, we calculated the geographical average for tornadoes for each year. We also weighted this average by the rated magnitude of each tornado and by the number of deaths from each tornado. …