Digital Commons Network^™

Protective Multi-Stressor Interactions In The Anthropocene: Key Considerations For Investigating Cross-Tolerance In A Conservation Context, Essie M Rodgers, Simone Baldanzi, Michael Collins, W Wesley Dowd, Lauric Feugere, Giovanna Mottola, Fanny Vermandele, Daniel F Gomez Isaza

School of Biological and Marine Sciences

In the Anthropocene, species are increasingly faced with multiple stressors that are more severe and less predictable than before. While multiple stressors often interact to affect organisms negatively, sometimes these interactions can be beneficial, enhancing resilience through cross-protection. Cross-protection interactions occur when exposure to one stressor, such as elevated temperature, enhances an organism’s tolerance to a different stressor, like hypoxia, through shared protective mechanisms or signaling pathways. Understanding the potential for cross-protection to combat rapid and diverse environmental change is crucial for conservation, as it potentially alters the predicted consequences of such change. Here, we outline 10 key considerations for …

Myth And Reality, Mircea Eliade

Hannah Arendt Marginalia - All

New York, Harper & Row, 1967

Call #: BL304 .E413

Contains marginalia, underlining, and is inscribed by the author

PDF Information: 62 pages – 22.5 MB

Achieving Outcomes In Analytical Chemistry While Focusing On Active Learning And Self-Care, Gretchen E. Potts Ph.D.

UTC Spring Research and Arts Conference

Pedagogy can support self-care and student outcomes in the chemistry classroom. In fact, intentional course design to support the whole student may improve overall student outcomes. A quantitative analysis lecture course that was designed synchronously online during COVID was transitioned to a face-to-face environment in an active learning classroom. Discussion boards were converted to daily group work that highlighted collaboration. Small adjustments were implemented to the course and syllabus design to help students manage stress and to encourage self-care. Frequent anonymous check-ins were used to monitor student learning progression. Additional anonymous prompts encouraged students to share study tips, how to …

Artificial Wetlands Provide Hope For Municipal Sewage Effluent Treatment And Biodiversity Declines, William T. Bryant

UTC Spring Research and Arts Conference

Wetlands provide habitat for a multitude of species worldwide and exist on almost every continent. They act as water filtration systems, cycle organic and inorganic nutrients, prevent flooding and mitigate storm damage. As the human population continues to expand and cities continue expanding, more infrastructure is needed for water treatment and providing green spaces for citizens to enjoy. This literature review analyzes the current data on the effectiveness of constructed wetlands in the treatment of sewage effluent and how they impact the biodiversity of the local ecosystem. The databases Web of Science, ProQuest and Agriculture, Ecosystems and Environment were utilized. …

Being, Man & Death: A Key To Heidegger, James M. Demske

Hannah Arendt Marginalia - All

University Press of Kentucky, 1970

Call #: B3279.H49 D4513

Light underlining & moderate marginal lining.

PDF Information: 37 pages – 16mb

The Survivor: An Anatomy Of Life In The Death Camps, Terrence Des Pres

Hannah Arendt Marginalia - All

New York : Oxford University Press, 1976

Call #: D810.J4 D474 1976

Contains edited markings, marginalia, and is an advance proof copy that is uncorrected

PDF Information: 69 pages – 4.6MB

Unless Peace Comes; A Scientific Forecast Of New Weapons, Nigel Calder

Hannah Arendt Marginalia - All

New York, Viking Press, 1968

Call #: U104 .C155 1968

Contains underlining and marginal lining.

PDF Information: 48 pages – 19mb

An Essay On Man, Ernest Cassirer

Hannah Arendt Marginalia - All

Garden City, NY: Doubleday, 1953 [c1944]

Call #: B3216.C33 E8 1953

Marginalia , underlining and marginal lining

PDF Information: 14 pages – 4 MB

Comparative Analysis Of Linear And Non-Linear Feature Selection For Breast Cancer Detection With Shap Analysis, Hamza Sabo Maccido

AUIQ Technical Engineering Science

Breast cancer remains one of the leading causes of mortality worldwide, emphasizing the critical need for accurate and efficient diagnostic tools. This study investigates the effectiveness of combining linear and non-linear feature selection methods-Principal Component Analysis (PCA), Pearson Correlation Coefficient (PCC), and Backpropagation Neural Networks (BNN) to improve breast cancer classification using machine learning models. We utilized the Wisconsin Breast Cancer Dataset to evaluate the performance of five classifiers-Support Vector Machine (SVM), K-Nearest Neighbor (KNN), Logistic Regression (LR), Decision Tree (DT), Naïve Bayes (NB) and Artificial Neural Network (ANN). The results demonstrated that BNN-selected features consistently outperformed PCA and PCC …

Retracted: Dynamics And Stability Analysis Of 8-Dimensional Hyperchaotic Systems: Study Of Lyapunov Exponents, Abdulsattar Abdullah Hamad, Nida Muhsin Ali, Muayyad Mahmood Khalil

Iraqi Journal for Computer Science and Mathematics

This research explores the complex dynamics of an 8D hyperchaotic system, focusing on its trajectory stability and behavior under various control parameters. By using numerical simulations, we investigate the relationship between the Lyapunov components and the stability of the system. It provides a quantitative measure of the chaos within the model of the matrix, whose derivation consists of the system's sensitivity to perturbation, simulating chaotic systems in high dimensions faces challenges such as high computational resource demands. Difficulty in ensuring numerical convergence and stability. The results highlight the profound impact of control parameters on the dynamic behavior of hyperchaotic systems. …

Corneal Elevation Maps Patterns Classification Using Correlation Method, Sura M. Ahmed, Nebras H. Ghaeb, Salman Yussof, Noor T. Al-Sharify, Husam Yahya Nser, Zainab T. Al-Sharify, Ong Hang See, Leong Yeng Weng

Iraqi Journal for Computer Science and Mathematics

The ophthalmologist uses various techniques to diagnose corneal abnormalities, including corneal topography and tomography devices. Currently generated color corneal elevation surface maps from topographic imaging devices are essential for detecting ocular diseases, while accurately classifying these maps to differentiate between different shapes remains an issue. This study aims to assess and compare parameters of the front and back corneal surface elevation map patterns of normal/abnormal corneas. Two hundred cases were randomly taken (100 normal and 100 abnormal) with a single normal reference image, and then an additional 25 cases were added later for the optimization process. The preprocessing of all …

Computational And In Vitro Investigation Of P. Crocatum Bioactive Compounds As Pancreatic Lipase Inhibitors, Gusnia Meilin Gholam, Dimas Andrianto, Dewi Anggraini Septaningsih, Mega Safithri

Karbala International Journal of Modern Science

Obesity, a prevalent metabolic disorder characterized by excessive fat accumulation, can severely affect overall health if left untreated. This study investigated the potential of a 70% ethanol extract from Piper crocatum (red betel) leaves as an in vitro inhibitor of pancreatic lipase (PL), supported by computational analyses to identify alternative compounds to orlistat. The phytochemical profile was characterized using LC-MS/MS, revealing alkaloids and terpenoids with contents of 1.1 ± 0.01 mg CE/g and 3.14 ± 0.3 mg UAE/g, respectively. The extract exhibited 49 ± 9.1% inhibition of PL activity. Molecular docking identified three promising compounds: calanolide A (10.43 kcal/mol), myricanone …

Hyperglycemia And Oral Health: A Review Of Dental Clinicians’ Perceptions And Practices Of Blood Glucose Monitoring In The Dental Office, Kathleen Wozniak

Dental Hygiene ETDs

This study aims to review the current practices and perceptions of dentists regarding the likelihood of dental professionals incorporating blood glucose monitoring into patient care protocol of patients with diabetes mellitus and prediabetes in dental offices. A survey link was shared by DentalOffices, a dental resource center. The survey included a series of questions which aimed to review dentists' current attitudes, practices, and considerations for implementation of in-office blood glucose testing as it relates to the treatment of patients with diabetes mellitus. Forty-seven dentists participated in the survey. This study determined blood glucose testing is not a common protocol or …

Baseline Testosterone Levels Peak During The Inactive Period In Male Degus (Octodon Degus), Yuta Sato , '26, Tate M. S. Garcia , '26, Josephine S. Low , '27, Carolyn M. Bauer

Biology Faculty Works

The steroid hormone testosterone is important for stimulating male reproductive processes including territory acquisition, mating displays, and spermatogenesis. When examining the relative effects of testosterone on reproductive processes, it is most reasonable to focus on peak baseline testosterone levels, especially for reproductive processes that may occur during specific times of day, such as mating and spermatogenesis. However, some studies have not found consistent positive relationships between circulating testosterone levels and reproductive variables. These nonsignificant relationships could be driven by methodology, as most studies in wild, free-living animals collect blood samples during an animals' active period, yet many species show peak …

Cocoa Polyphenols Alter The Fecal Microbiome Without Mitigating Colitis In Mice Fed Healthy Or Western Basal Diets, Eliza C. Stewart, Mohammed F. Almatani, Marcus Hayden, Giovanni Rompato, Jeremy Case, Samuel Rice, Korry J. Hintze, Abby D. Benninghoff

Animal, Dairy, and Veterinary Science Student Research

Background/Objectives: Chronic inflammation and Western-style diets elevate colorectal cancer (CRC) risk, particularly in individuals with colitis, a feature of inflammatory bowel disease (IBD). Diets rich in polyphenol-containing functional foods, such as cocoa, may reduce gut inflammation and modulate the gut microbiome. This study investigated the impact of cocoa polyphenol (CP) supplementation on inflammation and microbiome composition in mice with colitis, fed either a healthy or Western diet, before, during, and after the onset of disease. We hypothesized that CPs would attenuate inflammation and promote distinct shifts in the microbiome, especially in the context of a Western diet. Methods: …

In Silico Prediction Of Cytotoxic T-Cell Epitopes From Helicobacter Pylori Virulence Factors Using An Immunoinformatics Approach, Demy Valerie Chacon, Kiana Alika Co, Daphne Noreen Enriquez, Aubrey Love Labarda, Reanne Eden Manongsong, Edward Kevin B. Bragais

Biology Faculty Publications

Background: Helicobacter pylori infects approximately half of the global population, leading to gastric and duodenal ulcers. Despite the availability of antibiotics, challenges such as patient reluctance, high treatment costs, and antibiotic resistance limit their effectiveness, making vaccination a promising alternative. This study used immunoinformatics to identify candidate epitopes for a multiepitope vaccine construct against H. pylori.

Material and methods: The protein variability server was utilized for conservation analysis. The epitopes were screened for antigenicity, allergenicity, toxicity, cross-reactivity, and population coverage. Selected epitopes were docked with their corresponding human leukocyte antigen (HLA) alleles, and thermodynamic quantities were determined. Five virulence …

Health Impacts, Air Pollution And Electric Vehicles In California, Pufan Qi

Economics ETDs

This research examines the impact of electric vehicles (EVs) on air quality in California over the period from 2010 to 2021, as well as the implications of air pollution for respiratory health, organized into five chapters. The initial chapter provides background information and outlines the objectives, findings, and contributions. The second chapter examines the relationship between air quality and electric vehicles by utilizing fixed effect panel regression models. The third chapter employs panel regressions with Poisson control models to assess the correlation between changes in air quality resulting from electric vehicles and the prevalence of respiratory diseases. The fourth chapter …

Derivation Of Adjoint Based Error Estimates For Nonlinear Ordinary Differential Equations With Application To Multistage Sir Models With Demographics, Daniel Alcala

Mathematics & Statistics ETDs

Ordinary Differential Equations (ODEs) are central to the mathematical modeling of various real-world phenomena, from mechanical systems governed by Newton’s laws to epidemic dynamics described by SIR-type ODEs. Since many ODEs do not admit closed-form analytic solutions, we approximate them numerically (e.g., with Euler’s, Runge–Kutta, or other such methods). This raises the key question: How accurate are these numerical solutions? In particular, reliably estimating the error in some quantity of interest (QoI) at time T without having an exact solution is of great scientific interest.

The first main contribution of this thesis is the development and analysis of adjoint-based error …

Assessing The Ecological Drivers And Consequences Of Partial Migration In Hudson River Striped Bass Over Three Decades, Caitlin Egan Zimmer

Biology ETDs

Climate change and shifts in human land use have caused extensive impacts to the connectivity, structure, and resilience of aquatic populations. Partial migration (PM), where only some individuals from a population migrate while the rest remain resident, can mitigate population-level responses to environmental stressors. However, little is known of the underlying mechanisms promoting variation in migration and whether these shift over time. In the Hudson River Estuary, striped bass (Morone saxatilis) are known to exhibit anadromous PM behavior. Here, I measured carbon isotopes (δ¹³C) of essential amino acids in striped bass scales to determine variation in …

The Island Biogeography Of Mangrove-Dwelling Vertebrates: Isolation, Specialisation, And Extinction, Jian Xiong David Tan

Biology ETDs

Mangroves are highly dynamic ecosystems that are widely distributed across the coastlines of the tropics and subtropics. Despite their low plant diversity, mangroves host a disproportionately high number of terrestrial vertebrate taxa. However, mangrove specialists — taxa that only occur in mangrove habitats — exhibit a global distribution that is incongruous with the broader background distribution patterns of mangrove-associated fauna, exhibiting higher diversity in Australia and Southeast Asia. This dissertation therefore aims to assess how the diversity and distribution of mangrove specialist fauna may have been shaped by the historical biogeography of mangroves, and the effects of mangrove specialisation on …

Plant Reproductive Strategies Shift In Response To Restoration Using Beaver Dam Analogs, Laurel F. Martinez

Biology ETDs

As riparian communities become increasingly degraded, restoration treatments are being implemented in streams to recover ecosystem functions. In the Jemez Mountains, beaver dam analogs (BDAs) are used to restore degraded streams by connecting the floodplain and increasing the extent of anoxic soil conditions. These environmental disturbances are expected to alter how riparian plants recruit, particularly their allocation to seed-based and vegetative regeneration strategies. We investigated whether BDAs and associated changes in soil water filled pore space (WFPS) affected riparian plant recruitment. We investigated the number of flowering stems as a proxy for seed-based regeneration and rhizome length and mass as …

Ecoimmunology Of Dirty Physella Acuta Snails, Kevin Arthur Mcquirk

Biology ETDs

Research on Physella acuta, an invasive freshwater snail, reveals insights into its parasitology, fitness, and molecular biology. Morphological and molecular analyses revealed two distinct mitogenomic lineages, local (B) and invasive (A) strains of native P. acuta, both having comparable trematode infection rates, suggesting that the low infection rates observed from A in invaded regions result from "enemy release" rather than immune incompatibility. Fitness assessments showed that while lineages A and B performed similarly under laboratory conditions, rewilding experiments revealed significantly higher fitness in lineage A. Transcriptomic profiling supported these differences, with A snails showing greater immune-related gene expression and …

Spatial Ecology And Habitat Selection Of Eastern Pinesnakes: Case Study On The Importance Of Scale In Conservation Biology, Matthew Grisnik, Alan Jones, Rachel Brubaker, Andrew M. Grosse, Scott L. Parker

Biology

Species are in decline world-wide, driven by multiple factors including habitat fragmentation. Understanding the habitat selection processes of species in these fragmented landscapes has become a focus of ecological studies and is a major component of conservation plan development. However, understanding how landscape level processes influence patterns of habitat selection is often ignored. Here we assessed the influence of landscape level processes in the habitat selection of Eastern Pinesnakes, a species in decline, within a protected area in South Carolina, USA. Over the course of a year, we tracked 8 Eastern Pinesnakes within a small protected area. Snakes exhibited seasonal …

Optimization Of Formula, Stability Testing, And Antioxidant Activity Of Clay Masks As Skin Moisturizers, Naniek Widyaningrum, Agung Dwi Anggoro Bhakti, Alghafiqy Harya Evan Maulana, Amalia Safitri, Adinda Fajrah Ramadhani, Anisa Febriani, Anggit Naufal Hanafi, Thendi Abdul Arief

Pharmaceutical Sciences and Research

Clay masks are cosmetic formulations designed to adhere closely to the skin, effectively lifting contaminants, cleansing the face, and absorbing impurities. We made a clay mask containing active ingredients such as niacinamide, alpha arbutin, ceramide, and hyaluronic acid. A careful selection of ingredients is essential for ensuring safety and mitigating potential dermatological issues. This study aimed to evaluate the physical characteristics, stability, primary irritation potential, and moisturizing efficacy of this clay mask formulation. Kaolin and bentonite are the primary base materials. The research included formulation optimization and physical stability testing using a cycling test, where each cycle was conducted over …

Effects Of Neoadjuvant Immunotherapy On Hearing In Patients With Head And Neck Squamous Cell Carcinoma, Bryce Hambach, Anhelina Bilokon, John Lee, L. Noelle Allemang, Jennifer Chisholm, Chris K. Zalewski, Julie Christensen, Carmen C. Brewer, James L. Gulley, Clint T. Allen, Lisa L. Cunningham, Katharine A. Fernandez

SKMC Student Presentations and Publications

Immune checkpoint blockade (ICB) is a commonly used treatment modality for cancer with a growing list of oncologic indications. Ototoxicity is a potential immune-related adverse event of ICB treatment, but the risk of hearing loss after ICB remains unknown. This retrospective chart review sought to identify individuals who received ICB and had available audiometric data before and after treatment in order to identify clinically meaningful changes in hearing. This single center, institutional chart review examined hearing function data in patients who underwent audiometry before and after ICB treatment. Measures included pure tone thresholds, distortion product otoacoustic emissions (DPOAEs), tympanometry, and …

Using Triple Oxygen Isotopes To Investigate Water Usage In Desert Ecosystems, Cloe V. Knutson

Earth and Planetary Sciences ETDs

In arid environments, maintaining water balance can be more critical for survival than obtaining food. As droughts intensify, understanding how animals manage body water is essential. Triple oxygen isotope analysis provides a novel way to trace water sources in animals, distinguishing contributions from free water, food-derived oxygen, and atmospheric O₂. We developed an equilibration method using CO₂–H₂O oxygen exchange and measured δ^’18O and Δ^’17O values via tunable infrared laser direct spectroscopy (TILDAS). Validated against traditional fluorination methods, this technique enables streamlined analysis of whole blood and plant samples. Applied to …

Lifestyle Factors Contributing To Occupational Heat-Related Acute Kidney Injury, Jonathan Specht, Fabiano Amorim, Flavio De Castro Magalhaes, Zachary Mckenna, Zachary Schlader

Health, Exercise, and Sports Sciences ETDs

Workers worldwide are at risk for acute kidney injury due to hyperthermia and dehydration as a consequence of exertional heat stress. Limited research has explored the impact which lifestyle agents such as beverages, recreational drugs, and medications have on core temperature, hydration, and risk of acute kidney injury during physical work in the heat. To address this research gap, we explored the impact of three agents frequently used by construction workers on thermoregulation and markers of risk of acute kidney injury. First, we investigated the effect which ibuprofen ingestion has prior to one hour of running in the heat on …

Deaf Black Youth's Narratives About Identity And Education, Dominic A. Harrison

Language, Literacy, and Sociocultural Studies ETDs

This study is significant in exploring the different ways in which Deaf Black youth construct their identities through the use of narrative inquiry. Educators of Deaf youth should acknowledge how the identity journeys of Deaf Black youth are often affected by the school and home communities. This research employed narrative inquiry to understand how Deaf Black youth construct their identities as Black Deaf individuals. Using Critical Race Theory (CRT) as a theoretical framework with the guidance of Intersectionality and Dis/ability Critical Race Theory (DisCrit) lenses, the study specifically examined four Deaf Black youth’s narratives to highlight how they construct and …

Gallic, Aconitic, And Crocetin Acids As Potential Tnf Modulators: An Integrated Study Combining Molecular Docking, Dynamics Simulations, Admet Profiling, And Gene Expression Analysis, Adolat Manakbayeva, Ahdrey P. Bogoyavlenskiy, Timur Kerimov, Igor Yershov, Pavel Alexyuk, Madina Alexyuk, Vladimir Berezin, Vyacheslav Dushenkov

Publications and Research

Organic acids, as natural metabolites, play crucial roles in human metabolism and health. Tumor Necrosis Factor (TNF), a pivotal mediator in immune regulation and inflammation, is a key therapeutic target. We evaluated ten organic acids as TNF modulators using in silico molecular docking, followed by detailed ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) profiling and molecular dynamics (MD) simulations for three lead candidates: gallic, aconitic, and crocetin acids. Their effects on TNF gene expression were then assessed in vivo using a mouse leukocyte model. The in silico results indicated that crocetin had the highest TNF binding affinity (−5.6 to −4.6 …

Hidden Struggles, Shining Leaders: Black K–12 Leaders Navigating Microaggressions While Leading Predominantly White Or Majority-Minority Schools, Yinka Dallas

LMU Theses and Dissertations

This qualitative narrative study explored the lived experiences of eight Black educational leaders navigating microaggressions in predominantly White or majority-minority K–12 school settings in Southern California. Framed by Critical Race Theory (CRT) (Crenshaw, 1989; Ladson-Billings, 1998; Solórzano, 1998), the conceptual framework of microaggressions (Sue, 2010; Sue et al., 2008, 2007), and informed by the historical displacement of Black educators and leaders following Brown v. Board of Education (1954), the study examined how participants perceived and responded to microaggressions, as well as the reported psychological and physiological toll of these experiences, and strategies employed to address, cope with, and disrupted incidents …