Digital Commons Network^™

Inorganic Arsenite [I-As (Iii)] Represses Human Renal Progenitor Cell Characteristics And Induces Neoplastic-Like Transformation, Md Ehsanul Haque

Theses and Dissertations

Studies on populations exposed to inorganic arsenic (iAs) have shown an association between this particular exposure and the development of chronic kidney disease (CKD) and renal cell carcinoma (RCC). However, there are few studies addressing how acute exposure of the human kidney to iAs might lead to long-term alterations that might lead to CKD or RCC. This study’s hypothesis is that renal exposure to iAs might alter the renal cells responsible for the repair and regeneration of nephrons damaged by iAs exposure or other renal toxicants. The kidney possesses a minority epithelial cell population that co-express PROM1 and CD24 that …

Ai-Bms: Ai Battery Management System For Safe Uas Operations In High Electric And Magnetic Fields And Uncertain Conditions: Wind, Battery Drain, Temperature, And Payload, Tanzim Jim Hassan

Theses and Dissertations

Unmanned aerial systems/vehicles (UAS/UAVs) are increasingly utilized for inspecting high-voltage (HV) transmission (Tx) lines. However, operating in the vicinity of electric (E) and magnetic (H) fields can affect UAV control and battery performance. Pilots unfamiliar with high E/H field environments often struggle to accurately estimate remaining flight time, resulting in either premature mission terminations or crashes due to depleted batteries. To address these challenges, this thesis focuses on developing an intelligent Battery Management System (BMS) for UAVs to ensure safe and reliable surveillance operations under various uncertain conditions, such as wind gusts, temperature variations, E/H fields, battery drain, and payload …

Belongingness And Science Identity Of Underrepresented Students In Aerospace Sciences, Bella Hettich

Theses and Dissertations

Despite efforts to support underrepresented individuals—specifically those from racial, ethnic, and gender minority groups—they continue to face unique challenges that affect their belongingness in aerospace sciences, leading to issues with retention in educational programs and subsequent professional pathways. Such hindrances to personal achievement can also impede broader organizational goals. Addressing these challenges is critical, as supporting the success of underrepresented individuals fosters diverse perspectives, which are essential for driving innovation and maximizing organizational productivity. Just as importantly, ensuring that every individual, regardless of background, has access to opportunities and the support needed to succeed fulfills an ethical obligation. Upholding the …

Photometric Analysis Of Four Near-Earth Asteroids With A Convex Shape Model Of (25330) 1999 Kv4, Lucas James Hutton

Theses and Dissertations

Astrometric and photometric observations of asteroids provide information regarding their positions, rotation rates, axis of rotation, and shapes. Lightcurve inversion utilizes an asteroid’s change in brightness with respect to phase angle change, which maximizes ground-based observational data. This study investigated the rotational properties of four near-Earth asteroids (NEAs) with a single pole solution and convex shape model of (25330) 1999 KV4 using the lightcurve inversion method. Photometric observations were remotely obtained using the Skynet Robotic Telescope Network, andNOIRLAB’s Cerro-Tololo Inter-American Observatory’s (CTIO) 24” Ritchey-Chretien Prompt 3 Telescope. The data were calibrated using AstroImageJ software, and lightcurve analyses were performed using …

Nanoscale Frictional Properties Of Two-Dimensional Snse And Snse2 With Lateral Force Microscopy, Thomas Iken

Theses and Dissertations

In this study, we employed an atomic force microscopy-based lateral force microscopy technique to examine the nanoscale frictional characteristics of 2D SnSe and SnSe2 layers, and we compared these results with those of graphene, a commonly used solid lubricant. Our results revealed that both SnSe and SnSe2 layers exhibited superior lubricative performance compared to graphene with similar thicknesses. Experimental results were further substantiated by extensive Density Functional Theory calculations to understand the observed frictional properties of these materials.

Cisplatin-Induced Nephrotoxicity And Adaptive Responses In Renal Progenitor Cells: Molecular Insights From Transcriptomic And Proteomic Analyses, Eloho Ighofose

Theses and Dissertations

Cisplatin is a widely used chemotherapeutic agent known for its efficacy against various solid tumors, but its clinical utility is limited by dose-dependent nephrotoxicity. The renal proximal tubule, particularly its epithelial cell population, is highly susceptible to cisplatin-induced injury due to its role in solute transport and high metabolic activity. Recent advances suggest that renal progenitor cells play a key role in epithelial repair following nephrotoxic injury; however, the molecular mechanisms underlying their response to cisplatin remain poorly understood.This study investigates the impact of both acute and chronic cisplatin exposure on immortalized human renal progenitor cells (HRTPT, CD24⁺/CD133⁺) using a …

Thermally Induced Evolution Of The Cement Microannulus In Co2 Injection Wells, Jawad Ali Khan

Theses and Dissertations

Ensuring wellbore integrity during CO₂ injection is a critical challenge in Carbon Capture and Storage (CCS), as failures at the casing-cement and cement-formation interfaces can create potential leakage pathways. This dissertation presents a multi-scale, physics-based investigation into well integrity risks, integrating finite element analysis (FEA), thermal-mechanical-poroelastic modeling, and transient stress analysis to evaluate cement sheath stability, fracture-driven stress localization, and microannulus formation under various CCS conditions.

A key novelty of this research is the development of a fully coupled thermal-mechanical-poroelastic FEA framework using COMSOL Multiphysics, a renowned industry-standard software for multiphysics simulations. This model enables a dynamic, time-dependent assessment …

Attributions Of Blame In Cases Of Stealthing, Shane William Knutson

Theses and Dissertations

Nonconsensual condom removal (NCCR), also known as “stealthing”, is a form of sexual abuse where an individual removes the condom without their sexual partner’s knowledge. While research regarding prevalence of NCCR has been conducted over the past decade, there are still aspects of previous research on other forms of sexual abuse that did not account for cases of NCCR. One such gap in the current literature are studies that investigate how individuals attribute blame to the victims of NCCR. Previous research has shown that there are differences in how individuals attribute blame towards victims of sexual abuse based on different …

Investigation In Using Kinesthetic Learning Of Electricity And Magnetism In Scale-Up, Joseph Charley Langenwalter

Theses and Dissertations

This study investigates the effectiveness of incorporating kinesthetic learning activities into a SCALE-UP (Student-Centered Active Learning Environment with Upside-down Pedagogies) physics course to improve students' conceptual understanding of electricity and magnetism. This study aims to explore the effects of adding kinesthetic activities to a first-year 2nd semester physics course on student learning that included 92 students in three groups, traditional, scale-up control, scale-up activity classrooms. Nine active learning activities were designed to promote learning. A unique pre-post instrument was used to gauge student learning. Three questions from an instrument showed statistically significant improvement in student scores from the semester that …

Why Can't We Just Be: Native American College Student Sense Of Belonging At The University Of North Dakota, Gavin Michael Nadeau

Theses and Dissertations

Sense of belonging is a primary indicator of retention and persistence to graduation forNative American college students. Though more than doubling in the past 30 years, Native American college student enrollment has decreased since 2010 (197,000 in 2010 to 107,000 in 2021) (PNPI, 2021; NCES, n.d.). In 2020, Native American students’ 2nd year retention rate was more than 20% lower than their white peers at the University of North Dakota (UND, 2020). When college students of color feel like they belong, they are more likely to retain, persist, and graduate (Mowreader, 2024; Hurtado & Carter, 1997; Hurtado et al., 1999). …

When Fomo Meets The Keg: A Descriptive Case Study Of Binge Drinking In First-Year College Students At The University Of North Dakota, Angie Novak

Theses and Dissertations

Binge drinking among first-year college students is a persistent public health and academic issue, particularly during the transition to higher education. As students gain independence and navigate peer influence and campus norms, many perceive alcohol use as a central part of the college experience. This descriptive case study investigates the personal, environmental, and behavioral factors contributing to binge drinking among first-year students at the University of North Dakota (UND).The study, guided by Social Cognitive Theory (SCT), explored how students adopt and reinforce drinking behaviors through peer modeling, social expectations, and institutional culture. Qualitative data was collected through individual interviews with …

Teacher Skills Needed For Effective Participation In Multi-Tiered Systems Of Support (Mtss): A State Framework Analysis, Melissa Osborne

Theses and Dissertations

This study is a secondary data analysis that uses a validated rubric to score the degree of alignment between the teacher skills (TS) necessary for the effective implementation of Multi-Tiered Systems of Support (MTSS) and the preservice teacher training standards (PTS) across five states located in the North Central United States. This investigation also assessed whether states employing an MTSS process to establish special education eligibility for specific learning disabilities (SLD) exhibit higher alignment between TS and PTS compared to states that do not follow that process. Literature outlines the TS needed in an MTSS framework, but there is limited …

High-Fidelity Surface And Environment Simulation Using Immersive Virtual Reality For Lunar Analog Training, Shriya Pedaparthi

Theses and Dissertations

The study explores the integration of high-fidelity Virtual Reality (VR) into astronaut training for lunar analog missions. A realistic VR simulation was developed to represent lunar terrain, allowing participants to perform critical tasks under simulated lunar conditions. Specifically, participants navigated from a compromised lunar habitat (ILMAH) facing a pressure breach, to a secure facility, testing their ability to respond effectively to emergency scenarios. Participants underwent three sequential trials to assess how VR and physical constraints influence gait and performance: (1) a baseline trial measuring natural gait without equipment; (2) a trial incorporating a real spacesuit and lunar gravity simulated through …

Comparative Study Of Robotic And Manual Welding For Energy Consumption And Efficiency In A High Mix, Low Volume Manufacturing Environment, John Ruprecht

Theses and Dissertations

This study examines the comparative efficiency and energy consumption of manual versus robotic welding in high-mix, low-volume (HMLV) manufacturing environments. Traditional robotic welding systems have been predominantly used in low-mix, high-volume production due to their efficiency in repetitive tasks. However, the advent of collaborative robots (cobots) has democratized robotic automation for diverse manufacturing needs. Cobots allow flexibility in programming, enabling their deployment in HMLV environments characterized by hard product variety and smaller batch sizes. This research evaluates energy consumption, welding speed, and quality metrics across manual and cobotic welding systems. Data were gathered using energy meters and video analysis, focusing …

Negotiating Gender: A Qualitative Analysis Of Trans-Parasocial Relationships With Gen Z Social Media Users, Hannah Grace Scheffer-Wentz

Theses and Dissertations

The growth of social media and its functions as an online, international forum has been a growing topic of interest for researchers and the public alike. With the rise of native influencing and the incorporation of “organic” advertising, Social Media Influencers have grown in not just following and publicity with affiliate marketing and brand partnerships, but they have grown in social interest, as well. With the rise in technology and the introduction of Gen Z, who are digital natives, this has challenged previous understanding of online relationships, specifically with the expansion of Parasocial Relationship Theory to the online application of …

Eco-Friendly Synthesis Of Anemonin From 5-Hydroxymethylfurfural, A Biomass-Derived Starting Material, Diane Zefack Tangmi

Theses and Dissertations

Anemonin, a valuable cyclobutane containing dilactone is a bioactive natural product from Ranunculaceae plants. It holds great potential for applications in pharmaceuticals and materials science. However, traditional synthesis methods are hampered by low yields, toxic reagents, and environmental concerns, limiting its practical use. This study highlights the development of green and scalable synthetic strategies designed to achieve high yields while minimizing environmental impact. Our approach focuses on sustainable methodologies, including optimized steam and fractional distillation performed under mild conditions to reduce waste and energy demands. Protoanemonin’s natural ability to dimerize under mild heating offers a green approach to anemonin synthesis, …

Design And Fabrication Of Tpms-Based Bone Scaffolds: A Cost-Effective Approach Using Plga-Nha And 3d-Printed Pva Molds, Yasser Ahmed

Theses and Dissertations

This thesis introduces a new cost-effective method for fabricating bone scaffolds from triply periodic minimal surface (TPMS) geometries—namely Gyroid and Diamond structure—using a poly(lactic-co-glycolic acid)-nanohydroxyapatite (PLGA-nHA) composite and 3D-printed polyvinyl alcohol (PVA) molds. Current TPMS scaffold fabrication techniques depend on costly laser-based techniques like selective laser sintering and thus remain inaccessible. Herein, we reveal a cost-effective and repeatable indirect approach via fused deposition modeling (FDM) for printing water-soluble PVA molds, which are then iteratively cast filled with a PLGA-nHA solution. The protocol was optimized through concentration modulation and controlled evaporation of the solvent for optimum infiltration and uniformity in the …

Exploring The Experiences Of First-Year Pre-Nursing Students’ Sense Of Belonging In A Living-Learning Community And First-Year Seminar, Robyn Bancroft

Theses and Dissertations

Many factors may influence how a student experiences their first year adjusting to college life. The University of North Dakota, a public research institution located in Grand Forks, ND, recently implemented a nursing living-learning community (LLC) comprised of first-year, pre-nursing students, which also required the students to take a one-credit first-year seminar (FYS) together, known as UNIV 101 – Introduction to University Life. A total of 10 participants who resided within this living-learning community for a minimum of one academic year and were enrolled in the same section of UNIV 101 during their first semester submitted reflection papers. Additionally, eight …

Hillslope Degradation: Coarse Sands May Move Faster But Fines Dominate Flux, Robert Chance

Theses and Dissertations

Hillslopes are one of the most pervasive landforms on Earth yet the details of the processes that drive their evolution are not completely understood. Excluding boulders, the majority of mass and volume in soil-mantled hillslopes is composed of sand-sized and finer grains. Understanding the transport rates and governing transport mechanisms of these grains is therefore key to advancing our knowledge of hillslope evolution.This research investigates sand-sized sediment transport through field experiments at 20 sites tracking surface sediment motion and 11 sites measuring depth-dependent transport. These empirical results are compared against outputs from a novel grain-based hillslope diffusion simulation (GBHDS), which …

Exploring The Concepts Of Rematriation And The Sugpiaq/Alutiiq People’S Traditional Values And Ways Of Being To Address Historical Trauma: A Qualitative Study, Tara Lynn Christiansen-Stiller

Theses and Dissertations

This study is a collaborative exploration of the intersection of traditional Sugpiaq/Alutiiq values, historical trauma, and the process of rematriation. It aims to understand how these elements contribute to healing, resilience, and identity restoration within the Sugpiaq/Alutiiq community. Utilizing a qualitative research approach grounded in Interpretive Phenomenological Analysis (IPA), the study engages in in-depth interviews with Alutiiq elders, cultural leaders, and community members. Their lived experiences and perceptions are integral to the research process. The study seeks to uncover how Sugpiaq/Alutiiq cultural values, such as community solidarity, connection to land, and spirituality, protect against the impacts of historical trauma. Additionally, …

Congolese Refugee Narratives Of Belonging, Grief, And Cultural Continuity In Appalachia, Kayla Davis

Theses and Dissertations

This research examines the communicative challenges that Congolese refugees face after resettlement, particularly as they strive to reconstruct a sense of belonging in the United States that reflects their experiences in either their home country or secondary countries where they endured protracted displacement in refugee camps. Narrative qualitative research methods were used to conduct interviews with five Congolese refugees in Appalachia. Through qualitative thematic and lexical analysis derived from the interviews, the study reveals patterns of linguistic isolation, community continuity, and emotional displacement. A key finding is that participants often conceptualize community not as a geographic entity, but as an …

Exploring Refugee Students’ Experiences In Midwest Higher Education Environments: Culturally Responsive Practices For Educators, Rohana De Silva

Theses and Dissertations

This qualitative study examined the teaching and learning strategies used by highereducation faculty to support refugee students at a Midwestern university. Recognizing that refugee students bring diverse cultural, linguistic, and experiential backgrounds to academic environments, this research examined how instructional practices can either promote or hinder their educational success. Traditional teaching methods often fall short in addressing the complex needs of this student population. Using Yosso’s Community Cultural Wealth Framework, Bourdieu’s Theory of Cultural Capital, and Resilience Theory, this study analyzed the narratives of refugee students to uncover how their lived experiences influenced their educational journeys. Findings revealed that refugee …

Predictive Modeling For Multiphase Flow Boiling Heat Transfer By Integrating Computational Fluid Dynamics And Machine Learning Approaches, Mohamed Elfaham

Theses and Dissertations

The heat transfer process in multiphase flow systems becomes essential forindustrial applications and when phase change occurs. The heat transfer coefficients become more efficient during boiling and condensation processes when compared to single-phase fluid flow. The design of thermal systems requires knowledge about these coefficients together with their essential parameters. This study evaluates flow boiling heat transfer coefficients for low-global warming potential refrigerants which include pure ethanol and propane (R-290) and R- 600 and R-600A. The experimental database included more than 25 independent studies that covered various operating conditions and channel sizes and fluid properties. Existing empirical correlations were evaluated, …

Computational Prediction Of Hemolysis In Laminar Non-Newtonian Fluid, Nasim Gholizadeh

Theses and Dissertations

Hemolysis, the rupture of red blood cells (RBCs), is a critical concern in blood-circulating devices, requiring accurate predictions to ensure patient safety. This study investigates the sensitivity of hemolysis predictions to variations in viscosity models and hemolysis coefficients under complex flow conditions. Computational Fluid Dynamics (CFD) simulations were conducted using Ansys Fluent and OpenFoam on identical meshes with the FDA benchmark nozzle model. Under laminar flow conditions, CFD frameworks accurately predicted global variables, but variations in derived quantities, such as strain rate and vorticity, emerged due to differences in numerical solvers and gradient evaluation methods. These variations affected predictions of …

Laboratory Application Of An Aircraft Particle Imaging Probe To Characterize Levitated Ice Crystals And Their Aerodynamic Drag, Cheyenne Phoenix Harrison

Theses and Dissertations

Ice crystals in the upper atmosphere range in size from a few nanometers to a few millimeters, creating potential damage to vehicles traveling at hypersonic speeds; this problem has not yet been investigated with controlled laboratory techniques. This thesis investigates ice crystal impacts on high-speed flight vehicles and their aerodynamics by exploring a new method to combine ice crystal and shock wave experimental apparatuses to achieve experiments of observing ice crystals and shock waves interacting. The objectives of this research are: (1) to consistently produce levitated ice crystals in a setup that can feasibly release the ice crystals into a …

Measuring The Clinical Effectiveness Of Telenutrition Medical Nutrition Therapy Among American Indian And Alaska Native Adults Newly Diagnosed With Type 2 Diabetes, Charisse Lindsey Holiday

Theses and Dissertations

The COVID-19 global pandemic was the impetus of the transition from in-person medical nutrition therapy (MNT) visits to telephone MNT. This occurred without evaluation of its clinical effectiveness, especially for American Indians and Alaska Natives (AI/AN). It is known that in-person MNT is clinically effective at lowering hemoglobin A1c (A1c) and that people with diabetes who experience food insecurity have poorer health. However, research characterizing food insecurity among AI/ANs is limited. This retrospective observational analytical study was conducted at the Phoenix Indian Medical Center (PIMC) in Phoenix, Arizona to assess the clinical effectiveness of telephone delivered MNT services by a …

Energy Systems Optimization Techniques In The Oil And Gas Industry With Special Attention On Oil Field Reciprocating Compressors, Sean Jainarine

Theses and Dissertations

The oil and natural gas exploration and production industry is undergoing rapid growth, resulting in an increased number of operational wells and heightened potential for air emissions from oil and natural gas sources. Within production sites, compressors play a pivotal role and are often regarded as the "heart of a manufacturing plant" in the oil and gas sector. These crucial devices are designed to compress air or other gases to pressures higher than atmospheric pressure. Gas compression is typically achieved using devices with rotating blades or cylinders featuring reciprocating compressors while are essential for operations demanding high-pressures in small packages. …

The Ability Of The Millon Pre-Adolescent Clinical Inventory (M-Paci) To Distinguish Between Adhd And Non-Adhd Clinical Groups, Michael Jowkar

Theses and Dissertations

The M-PACI is a personality scale based on Millon’s biosocial personality theory designed to measure emerging personality patterns in pre-adolescents (9-12 years old). There is minimal published research on this inventory, particularly in clinical contexts. For this study, we used a data set collected at a Midwestern private practice clinic where children are assessed for ADHD and learning disabilities. This study looks at how those diagnosed with ADHD differ in emerging personality patterns and current clinical signs scales compared to those in a clinical sample who have not been diagnosed with ADHD. Some studies have shown differences between children diagnosed …

Impact Of Resin Grinding On Per- And Polyfluoroalkyl Substance Adsorption In Rapid Small-Scale Column Tests, Tihitna Gezahegn Mulugeta

Theses and Dissertations

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants with significant health risks. Among the different technologies for PFAS removal, adsorption is preferable due to low-cost, operational simplicity, and use of regenerable adsorbents. While pilot-scale fixed-bed columns are ideal for evaluating adsorption media, they are time- and resource-intensive. Rapid Small-Scale Column Tests (RSSCTs) offer a practical alternative, yet most studies have focused on granular activated carbon, with limited insight into ion exchange (IX) resins. Due to limited literature on the effect resin preparation on the performance of RSSCTs and their prediction accuracies are unexplored. This study investigates the effect of …

Using Machine Learning To Investigate Weather Impacts On Crop Yield For Probabilistic, Climate-Informed Predictive Crop Breeding, Levi Newell

Theses and Dissertations

As the world’s population continues to grow, the importance of food security willonly continue to increase, with some estimates requiring a global increase in food production between 59 and 98% by 2050. The agriculture industry is also a crucial economic driver, with the industry supporting 20% of the state of North Dakota’s workforce, and with a total valuation of $41.3 billion. The economic importance of this industry and the challenges of future growth prompt a need for data driven decision making into the future, particularly with predictive crop breeding. This is the method by which crops are developed that are …