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Articles 67291 - 67320 of 1823837
Full-Text Articles in Entire DC Network
Examining Educational Inequalities And Driving Science’S Next Generation Forward: Geobus Program Theory Evaluation, Elise M. Lorenzo
Examining Educational Inequalities And Driving Science’S Next Generation Forward: Geobus Program Theory Evaluation, Elise M. Lorenzo
Graduate Thesis and Dissertation post-2024
This study presents a theory-driven evaluation of GeoBus, a mobile science lab designed to deliver hands-on, “fun learning experiences” via a solar powered, technology-rich learning environment brought directly to K-12 students in Central Florida Title 1 schools. While STEM education is widely recognized as essential for promoting equity, many schools, particularly in under-resourced communities, continue to face barriers to accessing meaningful and inclusive science learning opportunities. GeoBus was created in response to this need, offering students an informal learning environment with exposure to geospatial technologies and interactive science content.
Drawing on mixed-methods data, including content from the GeoBus website and …
Effectiveness Of Leadership Rounding In Reducing Patient-Related Falls In A Medical-Surgical Unit, Elsie-Solange Mvoueng Nkoi-Mimba
Effectiveness Of Leadership Rounding In Reducing Patient-Related Falls In A Medical-Surgical Unit, Elsie-Solange Mvoueng Nkoi-Mimba
Walden Dissertations and Doctoral Studies
Summary In this Doctor of Nursing Practice (DNP) project, I evaluated whether the project site organization’s implementation of leadership rounding reduced patient falls within a medical-surgical unit. Despite established fall prevention strategies, the unit continued to experience ongoing incidents, prompting the implementation of structured leadership rounding. The practice-focused question assessed changes in fall rates over a 3-month postintervention period compared to the preceding 3 months. A retrospective chart review was conducted from December 2023 to June 2024, excluding March 2024 due to partial implementation. I used descriptive statistics to analyze trends. The average monthly fall rate remained stable at 2.67 …
Postglacial Erosional Response Of A Permafrost Landscape Across Decadal To Millenial Timescales, Aklavik Range, Arctic Canada, Bailey J. Nordin
Postglacial Erosional Response Of A Permafrost Landscape Across Decadal To Millenial Timescales, Aklavik Range, Arctic Canada, Bailey J. Nordin
Dartmouth College Master’s Theses
Rapid warming and permafrost thaw across Arctic landscapes are projected to drastically accelerate local erosion rates and sediment fluxes to downstream systems and the communities that rely on them. However, interpreting this signal of change first requires disentangling the relative contributions of postglacial landscape responses, periglacial processes, and modern warming to observed changes in erosion. To explore this problem, we combine a suite of geochronometers to examine erosion and deposition rates over timescales of 102–107 years across a periglacial alluvial fan and catchment system on the former margin of the Laurentide Ice Sheet in the Aklavik Range …
Anatomy Of An Ai Arms Race: U.S. And China Technological Dispute For Ai Leadership, Denisse I. Rojas Maldonado
Anatomy Of An Ai Arms Race: U.S. And China Technological Dispute For Ai Leadership, Denisse I. Rojas Maldonado
Dartmouth College Master’s Theses
The history of societies and the emergence of powerful states have been marked by cycles of conflict and war, followed by periods of cooperation that foster international stability. Similarly, the Cold War era saw a significant rise in military and economic capabilities, which highlighted a security dilemma as the former USSR and the United States sought to protect their national interests. Currently, artificial intelligence has expanded the scope of invisible warfare beyond the atomic bomb. Some scholars like Paul Scharre advocate that there is no arms race in place, and others support the idea of a healthy competition and collaboration …
Factors Affecting Extremity Fracture Risk In Children With Attention Deficit Hyperactivity Disorder, Yüksel Sümeyra Naralan, Esra Demi̇rel
Factors Affecting Extremity Fracture Risk In Children With Attention Deficit Hyperactivity Disorder, Yüksel Sümeyra Naralan, Esra Demi̇rel
Turkish Journal of Medical Sciences
Background/aim: Attention-Deficit/Hyperactivity Disorder (ADHD) is increasingly recognized not only for its behavioural and cognitive challenges but also for its potential implications in physical health, particularly injury risk. This study aimed to investigate the incidence of extremity fractures among children and adolescents diagnosed with ADHD and to evaluate the influence of demographic, clinical, and pharmacological variables—including ADHD subtypes and medication types—on fracture risk
Materials and Methods: This retrospective cross-sectional study included 754 children and adolescents aged 6–18 years who were diagnosed with ADHD according to DSM-5 criteria. Data were collected from electronic health records at a tertiary referral hospital. Variables …
Evaluation Of Teachers' Knowledge And Awareness About Autism Spectrum Disorder, Hami̇t Harun Bağci, Abi̇de Aksungur, Gülsüm Öztürk Emi̇ral, Erhan Şi̇mşek
Evaluation Of Teachers' Knowledge And Awareness About Autism Spectrum Disorder, Hami̇t Harun Bağci, Abi̇de Aksungur, Gülsüm Öztürk Emi̇ral, Erhan Şi̇mşek
Turkish Journal of Medical Sciences
Background/aim: Teachers play an essential role in the early identification of autism spectrum disorder (ASD) and associated difficulties in children. Increasing teachers’ knowledge of ASD can be helpful in identifying these children and making the necessary referrals. This study aimed to assess teachers’ knowledge and awareness of ASD and the factors affecting them.
Materials and methods: This is a cross-sectional study conducted among school counsellors. A total of 171 school counsellors were contacted; school visits were arranged by prior appointment, and the purpose of the study was explained. Data were collected using a questionnaire prepared by the researchers and the …
A Thematic Analysis Of The Perceived Impact Of Nil Policy On Athletic Identity, Career Maturity, And Black Male Student-Athletes’ Experience Of Transitioning Away From Football, Jesse Merise
Seton Hall University Dissertations and Theses (ETDs)
In 2007 the NCAA launched the widely recognized slogan, “There are over 380,000 student-athletes, and most of us will go pro in something other than sports.” Today, that figure has risen to over 540,000 and continues grow. Among them, Black male student-athletes (BMSAs) comprise 40% of collegiate football participation across all three divisions, a notable increase from 36% in 2012. Since only a small percentage of college football players go on to play professionally, it means that a large number of Black student-athletes will eventually have to leave sports and pursue other career paths.
This study examined the perceived impact …
The Benefits Of Establishing Attending Behavior Prior To The Discriminative Stimulus During Discrete-Trial Instruction: A Systematic Review, Ruben S. Pereira
The Benefits Of Establishing Attending Behavior Prior To The Discriminative Stimulus During Discrete-Trial Instruction: A Systematic Review, Ruben S. Pereira
Seton Hall University Dissertations and Theses (ETDs)
Discrete trial instruction (DTI) is one of the most effective and commonly used instructional strategies for teaching individuals with autism. Researchers and professionals have informally promoted the importance of establishing attending behavior prior to initiating discrete trials. However, some researchers have reported a lack of literature analyzing the effects of establishing attending behavior, prior to instruction, on skill acquisition. Therefore, the benefits of establishing attending as part of DTI remain unknown. The goal of the current thesis was to conduct a systematic review using PRISMA guidelines to search for published studies where attending behavior was a primary independent variable within …
Colostrum Extracellular Vesicle Are Neuroprotective In The Mptp Intoxicated Mouse Model Of Parkinson's Disease, Samia Akter
Colostrum Extracellular Vesicle Are Neuroprotective In The Mptp Intoxicated Mouse Model Of Parkinson's Disease, Samia Akter
Theses & Dissertations
Parkinson’s Disease (PD) is the second most common neurodegenerative disorder. Dopaminergic neuronal loss in the substantia nigra and the formation of Lewy bodies are the disease pathological hallmarks. We demonstrate that bovine colostrum extracellular vesicles (EVs) induce anti-inflammatory and neuroprotective activities during MPTP (methyl-4-phenyl-1,2,3,6-tetrahydropyridine) intoxication. Treatment these mice with colostrum EVs reduced the extent of activated microglia and neurodegenerative activities. RNA sequencing and transcriptomic analysis revealed a significant decrease in pro- inflammatory responses, as well as reduced recruitment and activation of immunocytes in affected brain tissues. Decreased expression of pro-inflammatory cytokines and chemokines, as well as suppressed canonical inflammasomes, was …
The Dual Impact Of Moral Injury: Links To Ptsd Symptoms And Disinhibited Externalizing In U.S. Combat Veterans, Bianca S. Islas
The Dual Impact Of Moral Injury: Links To Ptsd Symptoms And Disinhibited Externalizing In U.S. Combat Veterans, Bianca S. Islas
UNLV Theses, Dissertations, Professional Papers, and Capstones
Moral injury is an experience of psychological distress that occurs when a person’s morals are violated by themselves or others, including institutions and organizations. Such violations of morality can be impairing and have high rates of comorbidity with internalizing disorders (posttraumatic stress, depression, anxiety, suicidality), which may indicate that moral injury is a transdiagnostic construct. This study had four aims, which were accomplished using from a nationally representative, probability-based sample of 1,353 US military veterans. In the first aim, we created structural models of moral injury using the Moral Injury Events Scale (for which a bifactor structure with a specific …
Re: 2nd Quarter 2025 – Interim Site-Wide Surface Water Monitoring Data Report Silver Bow Creek Butte Area Npl Site, Butte Priority Soils Operable Unit Consent Decree-Civil Action No. Cv 89-039-Bu-She, Josh Bryson
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Collapse Of A Quantum Vortex In An Attractive Two-Dimensional Bose Gas, Sambit Banerjee, Kai Zhou, Shiva Kant Tiwari, Hikaru Tamura, Rongjie Li, Panayotis Kevrekidis, Simeon I. Mistakidis, Valentin Walther, Chen Lung Hung
Collapse Of A Quantum Vortex In An Attractive Two-Dimensional Bose Gas, Sambit Banerjee, Kai Zhou, Shiva Kant Tiwari, Hikaru Tamura, Rongjie Li, Panayotis Kevrekidis, Simeon I. Mistakidis, Valentin Walther, Chen Lung Hung
Physics Faculty Research & Creative Works
We experimentally and numerically study the collapse dynamics of a quantum vortex in a two-dimensional atomic superfluid following a fast interaction ramp from repulsion to attraction. We find the conditions and timescales for a superfluid vortex to radially converge into a quasi-stationary density profile, demonstrating the spontaneous formation of a vortex soliton like structure in an atomic Bose gas. We record an emergent self-similar dynamic caused by an azimuthal modulational instability, which amplifies initial density perturbations and leads to the eventual splitting of a solitonic ring profile or direct fragmentation of a superfluid into disordered, but roughly circular arrays of …
Exploration Of Language And Identities Among Study Abroad Participants In Non-Anglophone Context: Experience Of Asian International Students Studying Abroad In Belgium, Long Yat Ding
Journal of Comparative & International Higher Education
This Research Summary examines the study abroad experiences of Asian international students who study in non-anglophone Belgium. This research investigates how the experiences of mobility programme participants impact individual identity, with a focus on national, regional, and global citizenship identity. Eighteen qualitative in-depth semi-structured interviews were implemented. Mixed lived experiences and reactions towards national, regional and global identity after participation in mobility programmes were identified. Findings showcase non-anglophone European Higher Education and the study abroad experience of non-anglophone speakers from Asia in the post-COVID-19 era. The Research Summary provides a critical snapshot of Asian International students’ lived experience, especially under …
What Is Lost When Time Is Saved: Drawing In Collaboration With The Urban Periphery, Carmen Ribaudo
What Is Lost When Time Is Saved: Drawing In Collaboration With The Urban Periphery, Carmen Ribaudo
MFA in Visual Art
I pay attention to the overlooked spaces where land and industry meet, prompting me to wonder what can be gleaned in the oily and cracked urban periphery. With a focus on my hometown St. Louis, this industrial city is my subject matter. And so, I draw in a neighborhood bisected by a highway. I animate with sand near the river confluence on land preserved after a historic flood. I make my own bricks in this Brick City, setting up in locations of former terra cotta clay mines. I sit in the tension of what author Michael Martone calls the “midwestern …
Butte Priority Soils Operable Unit (Bpsou) Revised Butte Hill Revegetation Specifications, Mike Mcanulty, Eric Hassler
Butte Priority Soils Operable Unit (Bpsou) Revised Butte Hill Revegetation Specifications, Mike Mcanulty, Eric Hassler
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Re: 2025 Spring Semi-Annual – Interim Site-Wide Groundwater Monitoring Data Report Silver Bow Creek Butte Area Npl Site, Butte Priority Soils Operable Unit Consent Decree-Civil Action No. Cv 89-039-Bu-She, Josh Bryson
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Mathematical Modeling And Association Analysis Decipher The Impact Of The Gut Microbiome On Cancer Immunotherapy, Andreas G Hadjigeorgiou, Constantinos Harkos, Aditya K Mishra, Golnaz Morad, Sarah B Johnson, Nadim J Ajami, Jennifer A Wargo, Lance L Munn, Triantafyllos Stylianopoulos, Rakesh K Jain
Mathematical Modeling And Association Analysis Decipher The Impact Of The Gut Microbiome On Cancer Immunotherapy, Andreas G Hadjigeorgiou, Constantinos Harkos, Aditya K Mishra, Golnaz Morad, Sarah B Johnson, Nadim J Ajami, Jennifer A Wargo, Lance L Munn, Triantafyllos Stylianopoulos, Rakesh K Jain
Faculty, Staff and Student Publications
The gut microbiome has emerged as a key regulator of response to cancer immunotherapy. However, a better understanding of the underlying mechanisms by which the microbiome influences immunotherapy is needed to identify strategies to optimize outcomes. To this end, we developed a mathematical model to obtain insights into the effect of the microbiome on the immune system and immunotherapy response. This model was based on (i) gut microbiome data derived from preclinical studies, (ii) mathematical modeling of the antitumor immune response, (iii) association analysis of microbiome profiles with model-predicted immune profiles, and (iv) statistical models that correlate model parameters with …
Staff Education On The Columbia-Suicide Severity Rating Scale, Nathlie Ndokame
Staff Education On The Columbia-Suicide Severity Rating Scale, Nathlie Ndokame
Walden Dissertations and Doctoral Studies
Summary This was a staff education project aimed at improving nurse knowledge on the Columbia-Suicide Severity Rating Scale (C-SSRS) tool. The identified gap in practice was a lack of knowledge and confidence among psychiatric nursing staff in utilizing this evidence-based suicide risk assessment tool. This project question was as follows: Does the implementation of an education program for psychiatric nursing staff on the use of the Columbia-Suicide Severity Rating Scale improve knowledge of patients at risk for suicide? The project employed the ADDIE framework and the Johns Hopkins evidence-based practice model. A comprehensive literature search was conducted, yielding 67 relevant …
Rna’S Symphony: Harmonizing Splice Junctions And Exon Counts For A Novel Approach To Differential Splicing Analysis, Jelard Aquino
Rna’S Symphony: Harmonizing Splice Junctions And Exon Counts For A Novel Approach To Differential Splicing Analysis, Jelard Aquino
UNLV Theses, Dissertations, Professional Papers, and Capstones
Alternative Splicing (AS) plays a critical role in transcriptome complexity and cell-type-specific gene regulation, yet its analysis remains methodologically fragmented, especially in the context of noisy and sparse single-cell RNA sequencing (scRNA-seq) data. This dissertation addresses key computational challenges in AS detection by evaluating existing tools, developing integrative frameworks, and proposing new strategies for improving analysis accuracy in both bulk and single-cell contexts. In chapter 1, I present a comprehensive literature review of computational tools designed for detecting and quantifying AS from bulk and scRNA-seq data. This review outlines major methodological paradigms, including exon-based and splice junction-based approaches, and evaluates …
Hot Spring Associated Infectious Diseases In The Great Basin And Southwest, Matthew Bentz
Hot Spring Associated Infectious Diseases In The Great Basin And Southwest, Matthew Bentz
UNLV Theses, Dissertations, Professional Papers, and Capstones
Like all bodies of freshwater, natural hot springs can harbor pathogenic microorganisms that carry the threat of infectious disease. The unique chemistry, increased temperature, and popularity for bathing may alter the risk profile of hot springs compared to other natural bodies of water. Despite this risk, the role of hot springs as a reservoir for infectious diseases remains understudied, particularly within the context of regional public health. Nevada and the Great Basin/Southwest have increasingly promoted hot springs for the purposes of tourism, and they share a strong link to the cultural heritage of the region. The unknown risk profile and …
An Examination Of The Purity Culture Beliefs Scale And The Interaction Of Religiosity, Purity Culture Beliefs, And Pornography Use In A Census-Matched United States Sample, Kaelyn R. Griffin
An Examination Of The Purity Culture Beliefs Scale And The Interaction Of Religiosity, Purity Culture Beliefs, And Pornography Use In A Census-Matched United States Sample, Kaelyn R. Griffin
UNLV Theses, Dissertations, Professional Papers, and Capstones
The impacts of purity culture have been documented in the prevalence of abstinence-only sex education, perception of personal value tied to virginity, and shame and guilt related to sexual behavior. Similarly, models of moral incongruence often examine religiosity as a contributor of distress related to sexual behavior and pornography use, likely tapping into the influence of purity culture without directly naming its presence. This distinction is crucial due to the variety of religious beliefs and practices, some including purity culture and those without sexually restrictive beliefs and practices. Despite this, standardized measures for researching purity culture are limited. Ortiz (2018) …
Understanding Ore Deposit Scale Controls On Au Enrichment In Carlin-Type Au Mineralization: A High-Resolution Study Of The Rita K Deposit, Conner T. Callaway
Understanding Ore Deposit Scale Controls On Au Enrichment In Carlin-Type Au Mineralization: A High-Resolution Study Of The Rita K Deposit, Conner T. Callaway
UNLV Theses, Dissertations, Professional Papers, and Capstones
Controls on the distribution of gold (Au) within the Rita K Carlin-type deposit are poorly understood. The primary Au-bearing carbonate unit Wispy, is a bioturbated muddy limestone with debris flow clasts that range in size but are typically >5 cm occurring in the lower sections. The orebody is described as a syncline-anticline pair that hosts high-grade Au ore in the fold hinges. The spatial relationship between Au mineralization and fold hinges suggests that shortening due to folding is an important mechanism producing Au-enriched zones. However, the exact mechanism of Au enrichment and deposit-scale controls on Au distribution and fluid evolution …
Empowering Science With The World's First High Accuracy And High Throughput Functional Assay, Christopher Giacoletto
Empowering Science With The World's First High Accuracy And High Throughput Functional Assay, Christopher Giacoletto
UNLV Theses, Dissertations, Professional Papers, and Capstones
Understanding the functional consequences of genetic mutations remains a central challenge in modern biology, with far-reaching implications for human health and disease. While early systematic methods like alanine scanning and phage display provided foundational insights into protein structure and function, the emergence of high-throughput approaches—such as Multiplexed Assays of Variant Effect (MAVEs)—and predictive tools powered by artificial intelligence have vastly expanded our ability to profile mutational landscapes. However, these methods are often constrained by trade-offs between accuracy, scalability, and biological relevance.This dissertation presents the development and application of the GigaAssay, the world’s first high-throughput functional assay capable of delivering both …
Functional Biopolymers Applied To Sustainable Technologies In The Environment And Healthcare, Fengjie He
Functional Biopolymers Applied To Sustainable Technologies In The Environment And Healthcare, Fengjie He
UNLV Theses, Dissertations, Professional Papers, and Capstones
Biodegradable polymeric materials (biopolymers) are naturally derived materials known for their excellent biocompatibility, biodegradability, sustainability, and versatile chemical functionality. They have attracted increasing attention in various applications as alternative to synthetic materials ranging from food packaging to tissue engineering. Meanwhile, with intrinsic advantages, biopolymers have also emerged as promising materials in addressing contemporary challenges in both biomedical and environmental fields. Motivated by the significant potential of biopolymers and the growing need for sustainable materials, my research focuses on the design and engineering of biodegradable polymers with novel modification methods and application directions. In this work, two representative biopolymers are selected: …
Integrated Uav Platform For Multi-Spectral, Thermal, And Eos Imaging In Wildfire Monitoring And Modeling, Md Shariful Islam
Integrated Uav Platform For Multi-Spectral, Thermal, And Eos Imaging In Wildfire Monitoring And Modeling, Md Shariful Islam
UNLV Theses, Dissertations, Professional Papers, and Capstones
This thesis presents the design and development of a modular unmanned aerial vehicle (UAV) system based on a quadcopter platform for flexible and efficient wildfire-related multimodal image acquisition. Addressing key limitations in ecological UAV monitoring such as sensor inflexibility, time-consuming reconfiguration, and imprecise image georeferencing, the system introduces a versatile payload integration framework supporting three distinct imaging sensors: MicaSense Altum-PT, FLIR Vue Pro R, and Sony Alpha 6000.All onboard components, including the flight controller, autopilot software, GNSS module, motors and ESCs, were selected to optimize stability and payload performance. A gimbal-free, downward-facing mount simplifies field deployment, while custom integration enables …
Housewerk: How Drag Performers Engage In Emotional Labor While Navigating Community Care, Steph O. Landeros
Housewerk: How Drag Performers Engage In Emotional Labor While Navigating Community Care, Steph O. Landeros
UNLV Theses, Dissertations, Professional Papers, and Capstones
This dissertation examines drag performance as a form of service labor shaped by emotional labor, community care, and identity-based inequality. Drawing on interviews with drag performers shows how drag labor blends artistic skill, emotional regulation, interpersonal care, and entrepreneurial labor. While these demands mirror service sector roles in other industries, drag remains underrecognized and undervalued, particularly for performers who do not conform to white, cisgender norms. The study introduces Housewerk—an adaptation of Marlon Bailey’s concept of housework (Bailey, 2013)—to describe the mix of paid and unpaid labor drag performers engage in. Housewerk captures how performers must balance self-preservation (branding, income, …
Mechanisms Of Gold Enrichment In Seafloor Massive Sulfide Deposits: A Study On The Higashi-Aogashima Hydrothermal Field, Claudia Martinez
Mechanisms Of Gold Enrichment In Seafloor Massive Sulfide Deposits: A Study On The Higashi-Aogashima Hydrothermal Field, Claudia Martinez
UNLV Theses, Dissertations, Professional Papers, and Capstones
The study of Seafloor Massive Sulfides (SMS) deposit formation is vital for assessing both the economic potential and environmental risks posed by future marine mining projects. Metal-rich SMS deposits form in hydrothermal vent systems within tectonically active regions, such as back-arc basins, where faults enhance crustal permeability, enabling fluid migration driven by magmatic heat sources at depth in the crust. Currently our understanding of SMS formation processes is based on bulk-rock geochemical and isotopic data, lacking the necessary spatial and temporal resolution to understand ore forming processes. As a result, critical gaps remain in understanding the exact mechanisms responsible for …
Ecological Momentary Assessment Of Mood, Affect, And Perceived Criticism: Investigation Of Daily Patterns And Family Impact, Kayla Mcginty
Ecological Momentary Assessment Of Mood, Affect, And Perceived Criticism: Investigation Of Daily Patterns And Family Impact, Kayla Mcginty
UNLV Theses, Dissertations, Professional Papers, and Capstones
Perceived criticism (PC) is a component of expressed emotion (EE) that assesses an individual’s perceptions of the criticism that they are exposed to within their interpersonal relationships. PC is elevated among individuals with mood disorders, and mood and mood symptoms act as both a predictor and an outcome of PC. However, few studies have examined the relationship between PC and affect, a more momentary measure of emotion that can serve as a guide to underlying mood. Additionally, limited research has examined how PC within family relationships compares to other interpersonal interactions. Understanding the relationship between momentary affect and PC and …
Exploring The Processing Of Objects, Settings, And Global Properties In Natural Auditory Scenes, Margaret A. Mcmullin
Exploring The Processing Of Objects, Settings, And Global Properties In Natural Auditory Scenes, Margaret A. Mcmullin
UNLV Theses, Dissertations, Professional Papers, and Capstones
Our auditory system has a remarkable ability to make sense of complex environments, allowing us to identify what we are hearing and where sounds come from. This process of auditory scene analysis is essential for situational awareness, decision-making, and effective communication in daily life. While much is known about how listeners segregate and identify individual sound sources (e.g., voices), less is understood about how global properties of a scene (e.g., openness, naturalness) contribute to perception. This dissertation examined how object- and setting-level information in natural auditory scenes are processed, and whether they rely on distinct or overlapping mechanisms. In Experiment …
Investigating Information Extraction And Language Models In Medical Domain Text Processing, Pouyan Nahed
Investigating Information Extraction And Language Models In Medical Domain Text Processing, Pouyan Nahed
UNLV Theses, Dissertations, Professional Papers, and Capstones
This dissertation demonstrates that carefully adapted language-model pipelines can transform unstructured clinical-trial and pharmacological prose into reliable, low-latency structured data. Four interconnected studies support this claim.Tri-AL platform. An open-source dashboard ingests all 440 k+ ClinicalTrials.gov records—including every historical revision—into a normalized schema and parses the 20 GB XML archive over 10x faster than a BeautifulSoup baseline, while exposing hooks for demographic analytics and supporting integration of user-defined modules. Clinical trial summarization. An encoder–decoder model is trained on 57k description–summary pairs to condense clinical trials into a few sentences. ROUGE evaluation shows a 20% improvement over the baseline, while graph-based evaluation …