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Articles 9361 - 9390 of 10505
Full-Text Articles in Entire DC Network
Measles Cases Surge Worldwide, Infecting 10.3 Million People In 2023
Measles Cases Surge Worldwide, Infecting 10.3 Million People In 2023
Neurosciences
No abstract provided.
International Society Of Sports Nutrition Position Stand: Β-Hydroxy-Β-Methylbutyrate (Hmb), John A. Rathmacher, Lisa M. Pitchford, Jeffrey R. Stout, Jeremy R. Townsend, Ralf Jäger, Richard B. Kreider, Bill I. Campbell, Chad M. Kerksick, Patrick S. Harty, Darren G. Candow, Brandon M. Roberts, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Douglas S. Kalman, Jose Antonio
International Society Of Sports Nutrition Position Stand: Β-Hydroxy-Β-Methylbutyrate (Hmb), John A. Rathmacher, Lisa M. Pitchford, Jeffrey R. Stout, Jeremy R. Townsend, Ralf Jäger, Richard B. Kreider, Bill I. Campbell, Chad M. Kerksick, Patrick S. Harty, Darren G. Candow, Brandon M. Roberts, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Douglas S. Kalman, Jose Antonio
Faculty Publications
Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on an analysis of the literature regarding the effects of β-Hydroxy-β-Methylbutyrate (HMB). The following 12 points have been approved by the Research Committee of the Society: 1. HMB is a metabolite of the amino acid leucine that is naturally produced in both humans and other animals. Two forms of HMB have been studied: Calcium HMB (HMB-Ca) and a free acid form of HMB (HMB-FA). HMB-FA appears to lead to increased appearance of HMB in the bloodstream when compared to HMB-Ca, though recent results are mixed. 2. …
Measuring The Clinical Effectiveness Of Telenutrition Medical Nutrition Therapy Among American Indian And Alaska Native Adults Newly Diagnosed With Type 2 Diabetes, Charisse Lindsey Holiday
Measuring The Clinical Effectiveness Of Telenutrition Medical Nutrition Therapy Among American Indian And Alaska Native Adults Newly Diagnosed With Type 2 Diabetes, Charisse Lindsey Holiday
Theses and Dissertations
The COVID-19 global pandemic was the impetus of the transition from in-person medical nutrition therapy (MNT) visits to telephone MNT. This occurred without evaluation of its clinical effectiveness, especially for American Indians and Alaska Natives (AI/AN). It is known that in-person MNT is clinically effective at lowering hemoglobin A1c (A1c) and that people with diabetes who experience food insecurity have poorer health. However, research characterizing food insecurity among AI/ANs is limited. This retrospective observational analytical study was conducted at the Phoenix Indian Medical Center (PIMC) in Phoenix, Arizona to assess the clinical effectiveness of telephone delivered MNT services by a …
The Impact Of Poverty On Student Achievement And Effective Strategies To Close The Gap, Alexis L. Sorbo
The Impact Of Poverty On Student Achievement And Effective Strategies To Close The Gap, Alexis L. Sorbo
All Electronic Theses and Dissertations
Poverty has a negative impact on student achievement through a variety of factors such as student engagement, motivation, parent engagement, and resource access. This thesis explores the relationship between poverty and academic achievement by examining how disparities related to socioeconomic status impact a student’s cognitive and emotional development. The reviewed research also investigates effective strategies that teachers and administrators can implement to mitigate these effects, such as using evidence-based instruction and behavior management strategies in the classroom, increasing parent engagement, applying regular, high-quality professional development, and providing equitable access to resources. Research highlights the importance of a holistic approach to …
An Overview Of The Current Scientific Evidence On The Biological Properties Of Abelmoschus Esculentus (L.) Moench (Okra), Shun Wan Chan, Hei Tung, Lydia Chan
An Overview Of The Current Scientific Evidence On The Biological Properties Of Abelmoschus Esculentus (L.) Moench (Okra), Shun Wan Chan, Hei Tung, Lydia Chan
Department of Food and Health Sciences
Abelmoschus esculentus (L.) Moench, commonly known as okra or lady’s finger, is an annual flowering plant belonging to the Malvaceae family. Okra is a native plant in Africa as well as a traditional medicine in Africa and India for treating different diseases and conditions. Today, okra is widely consumed as a vegetable and is increasingly recognized as a superfood due to its rich nutritional profile and potential pharmacological benefits. Research indicates that okra exhibits a range of biological activities, including antidiabetic, antihyperlipidemic, antifatigue, vasoprotective, hepatoprotective, antitumor, anti-inflammatory, and antimicrobial effects. Despite its promising therapeutic potential, research on the active compounds …
Combined Use Of Esculetin And Probiotics In Preventing Parkinson’S Disease In Mice, Shun Wan Chan, Meng Zhang, Huan Zhang
Combined Use Of Esculetin And Probiotics In Preventing Parkinson’S Disease In Mice, Shun Wan Chan, Meng Zhang, Huan Zhang
Department of Food and Health Sciences
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder affecting about 0.1-0.2% of the population, with a higher prevalence among the elderly [1]. As the disease progresses, its motor symptoms worsen, significantly impairing patients' self-care abilities and quality of life. Due to the lack of definitive early-stage diagnosis and effective treatments to slow neurodegeneration, developing preventive measures is essential to alleviate the social and economic burdens associated with PD. Emerging evidence suggests that dietary components, such as probiotics, can modulate the gut-brain axis to potentially prevent PD development. Previous research has highlighted esculetin, a natural coumarin, for its neuroprotective properties in …
Neuroprotective Effects Of Esculetin And Probiotics In 6-Hydroxydopamine-Induced Parkinson’S Disease, Shun Wan Chan, Hei Tung, Lydia Chan, Meng Zhang, Huan Zhang, Kam Wah, Daniel Mok
Neuroprotective Effects Of Esculetin And Probiotics In 6-Hydroxydopamine-Induced Parkinson’S Disease, Shun Wan Chan, Hei Tung, Lydia Chan, Meng Zhang, Huan Zhang, Kam Wah, Daniel Mok
Department of Food and Health Sciences
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the progressive impairment of motor and non-motor functions, particularly affecting aging populations. Approximately 0.1-0.2% of the global population is impacted, with the rate significantly higher among the elderly. Currently, an estimated 10 million individuals are living with PD, a number projected to rise to 25 million by 2050 due to aging demographics. The burden is notably greater in males, and prevalence increases with age. As PD progresses, it leads to debilitating motor decline, severely compromising patients' independence and quality of life. These challenges are compounded by the current inability to definitively …
An Overview Of The Current Scientific Evidence On The Biological Properties Of Abelmoschus Esculentus (L.) Moench (Okra), Shun Wan Chan, Hei Tung, Lydia Chan, Tsun Ka, Carten Kwok, Yam Fung Ng
An Overview Of The Current Scientific Evidence On The Biological Properties Of Abelmoschus Esculentus (L.) Moench (Okra), Shun Wan Chan, Hei Tung, Lydia Chan, Tsun Ka, Carten Kwok, Yam Fung Ng
Department of Food and Health Sciences
Abelmoschus esculentus (L.) Moench, commonly known as okra or lady’s finger, is an annual flowering plant belonging to the Malvaceae family. Okra is a native plant in Africa as well as a traditional medicine in Africa and India for treating different diseases and conditions. Today, okra is widely consumed as a vegetable and is increasingly recognized as a superfood due to its rich nutritional profile and potential pharmacological benefits. Research indicates that okra exhibits a range of biological activities, including antidiabetic, antihyperlipidemic, antifatigue, vasoprotective, hepatoprotective, antitumor, anti-inflammatory, and antimicrobial effects. Despite its promising therapeutic potential, research on the active compounds …
Female Brain And Endocrinological Research–Veteran (Fember-Vet) Study: A Study Protocol For Identifying Endocrinological, Lifestyle And Psychosocial Determinants Of Brain Health Outcomes In Female Veterans For Future Intervention Success, Tamlyn Watermeyer, Elliott Atkinson, Glyn Howatson, Gill Mcgill, Christina Dodds, Paul Ansdell, Chinedu Momoh
Female Brain And Endocrinological Research–Veteran (Fember-Vet) Study: A Study Protocol For Identifying Endocrinological, Lifestyle And Psychosocial Determinants Of Brain Health Outcomes In Female Veterans For Future Intervention Success, Tamlyn Watermeyer, Elliott Atkinson, Glyn Howatson, Gill Mcgill, Christina Dodds, Paul Ansdell, Chinedu Momoh
Brain and Mind Institute
Background: Recent studies have demonstrated a greater risk of dementia in female veterans compared to civilians; with the highest prevalence noted for former service women with a diagnosis of psychiatric (trauma, alcoholism, depression), and/or a physical health condition (brain injury, insomnia, diabetes). Such findings highlight the need for increased and early screening of medical and psychiatric conditions, and indeed dementia, in the female veteran population. Further, they call for a better understanding of the underlying biopsychosocial mechanisms that might confer heightened risk for female veterans, to tailor preventative and interventional strategies that support brain health across the lifespan.
Methods …
Effect Of Forage Allocation On Steer Performance When Grazing Cereal Rye, Shelby L. Davies-Jenkins, Abigail M. Sartin, Daren D. Redfearn, Mary E. Drewnoski
Effect Of Forage Allocation On Steer Performance When Grazing Cereal Rye, Shelby L. Davies-Jenkins, Abigail M. Sartin, Daren D. Redfearn, Mary E. Drewnoski
Nebraska Beef Cattle Reports
Summary with Implications
Cereal rye is the most common cover crop planted today. With its good winter tolerance and rapid spring growth during a gap in perennial pasture productivity, it is an attractive forage source in early spring. Unfortunately, optimum stocking rates and how they are related to forage biomass availability are unknown. The study objective was to understand the effect of forage allowance on steer performance when rotationally grazing fall-planted cereal rye in spring. Stocking rate was negatively correlated with pounds of forage offered. Surprisingly, amount of forage offered related to average daily gain. Growing steers grazing cereal rye …
Assessment On The Capacity Of Local Government Units In Implementing The Rules And Regulations Of Republic Act No. 11930 And A Cost Study Of Implementing An Anti-Osaec Program, Ma. Divina Gracia Roldan, Ador R. Torneo, Maria Caridad Tarroja, Marites M. Tiongco, Ma. Ella C. Oplas
Assessment On The Capacity Of Local Government Units In Implementing The Rules And Regulations Of Republic Act No. 11930 And A Cost Study Of Implementing An Anti-Osaec Program, Ma. Divina Gracia Roldan, Ador R. Torneo, Maria Caridad Tarroja, Marites M. Tiongco, Ma. Ella C. Oplas
SDRC Projects
This study assessed the capacity of selected local government units (LGUs) to implement Republic Act No. 11930, or the Anti-Online Sexual Abuse or Exploitation of Children and Anti-Child Sexual Abuse or Exploitation Materials Act, and its Implementing Rules and Regulations. It examined four dimensions of local capacity: legal, administrative, relational, and fiscal. It also assessed the costs and investments required to implement and sustain local anti-OSAEC programs.
The study employed a mixed-method approach in Manila, Dasmariñas City in Cavite, and Llorente in Eastern Samar. The qualitative component comprised 15 key informant interviews and 10 focus group discussions with representatives from …
Why Domestic Violence Offenders Don't Give Up Their Guns, Natalie Nanasi
Why Domestic Violence Offenders Don't Give Up Their Guns, Natalie Nanasi
Faculty Journal Articles and Book Chapters
Perpetrators of intimate partner violence are barred by federal law and many states' laws from possessing firearms. While such prohibitions enjoy popular support, they are sporadically and inconsistently enforced, placing the lives of survivors at risk when offenders do not voluntarily comply. Many experts, including this author, have offered legal and policy solutions to increase the likelihood that perpetrators of domestic violence will either willingly relinquish their guns or otherwise be dispossessed of them. But these proposals may have been premature.
This Article is the first to take a step back and inquire why offenders do not surrender their firearms …
Automating The Amino Acid Identification In Elliptical Dichroism Spectrometer With Machine Learning, Ridhanya Sree Balamurugan, Yusuf Asad, Tommy Gao, Dharmakeerthi Nawarathna, Umamaheswara Rao Tida, Dali Sun
Automating The Amino Acid Identification In Elliptical Dichroism Spectrometer With Machine Learning, Ridhanya Sree Balamurugan, Yusuf Asad, Tommy Gao, Dharmakeerthi Nawarathna, Umamaheswara Rao Tida, Dali Sun
Electrical & Computer Engineering Faculty Publications
Amino acid identification is crucial across various scientific disciplines, including biochemistry, pharmaceutical research, and medical diagnostics. However, traditional methods such as mass spectrometry require extensive sample preparation and are time-consuming, complex and costly. Therefore, this study presents a pioneering Machine Learning (ML) approach for automatic amino acid identification by utilizing the unique absorption profiles from an Elliptical Dichroism (ED) spectrometer. Advanced data preprocessing techniques and ML algorithms to learn patterns from the absorption profiles that distinguish different amino acids were investigated to prove the feasibility of this approach. The results show that ML can potentially revolutionize the amino acid analysis …
Obesity Prediction From Structural Mri Using Conformal Deep Learning With Uncertainty Quantification, W. Farzana, A. G. A. Temtam, B. Humud-Arboleda, L. Ma, M. Bean, F. Gerard Moeller, K. M. Iftekharuddin
Obesity Prediction From Structural Mri Using Conformal Deep Learning With Uncertainty Quantification, W. Farzana, A. G. A. Temtam, B. Humud-Arboleda, L. Ma, M. Bean, F. Gerard Moeller, K. M. Iftekharuddin
Electrical & Computer Engineering Faculty Publications
Obesity arises from a neurobehavioral disorder in which the brain’s regulation of hunger and food intake is impaired, leading to an imbalance between energy consumption and expenditure. One key phenotype associated with obesity is body mass index (BMI). BMI is influenced by multiple causal pathways driven by behavioral, metabolic, and genetic factors. Traditional obesity prediction studies often rely on magnetic resonance imaging (MRI) voxel-based morphometry to correlate BMI with obesity-related clinical measurements and brain structure, predominantly gray matter volume (GMV). However, the altered brain regions are variable and widespread between studies, with some literature presenting contradictory results between BMI and …
How To Approach Medical Education Research, Stefanie Attardi, Jeff Cross, Sarah Lerchenfeldt
How To Approach Medical Education Research, Stefanie Attardi, Jeff Cross, Sarah Lerchenfeldt
Books and Book Chapters
Medical education research blends two of the core functions of academic medicine: teaching and scholarship. Its value is increasingly recognized in promotion and tenure decisions, and in the number of funding sources available. Similar to other types of research, it starts with a well-crafted question and a thorough review of the literature. For a successful project, it is critical to select the research design that can best answer the research question, keeping in mind its advantages and limitations. Because the research design must also adhere to ethical principles, working closely with the local Institutional Review Board prior to starting the …
Exploring The Reassessment Of Palliative Home Care Clients: A Mixed Methods Study, Maya Canham
Exploring The Reassessment Of Palliative Home Care Clients: A Mixed Methods Study, Maya Canham
Theses and Dissertations (Comprehensive)
Introduction: The timely reassessment of clients receiving palliative home care (HC) is critical for supporting clinicians with care planning and service delivery. However, there is little information on the frequency of reassessments and factors driving reassessment in palliative HC clients.
Objectives: The objectives of this study were to: (i) determine the proportion of palliative HC clients reassessed with the interRAI Palliative Care (interRAI PC) instrument, (ii) calculate the average interRAI PC reassessment interval, (iii) identify the key factors driving interRAI PC reassessment at various intervals, and (iv) explore the factors that influence palliative HC clinicians to reassess their clients in …
Assessing Local Public Officials' Roles, Challenges, And Opportunities Encountered When Integrating Newcomers: A Case Study To Evaluate The Cities Of Rochester And Worthington., John Dassou
School of Business Student Theses and Dissertations
Immigrants’ integration plays an important part in policy concerns and goals in many local governments since it is a major issue for local officials to integrate immigrants and incorporate them into the host community successfully. Concurrently, it is important to know the roles of local public officials, host communities, and immigrants in the process. The purpose of this study is to assess the challenges that local officials face, and how they handle these encounters effectively and efficiently. Greater collaboration between all stakeholders, social cohesion, and collective efforts implies the idea that immigrants’ integration depends on many players and factors. It …
Timing Of Migration And Seasonal Movements Of Arctic Grayling (Thymallus Arcticus) In Relation To Water Temperature In The Kakisa River And Upper Mackenzie River, Nwt: Results From An Acoustic Telemetry Study., Levi Snook
Theses and Dissertations (Comprehensive)
Arctic grayling (Thymallus arcticus) are a cold-water salmonid that inhabit waterbodies throughout the circumpolar regions of the northern hemisphere. In the last decade, Ka'a'gee Tu First Nation members as well as local sport fishers, have observed lower catches of Arctic grayling during their annual spawning run in the Kakisa River, NWT. Many potential causes of this decline have been hypothesized including climate change and over harvesting. Outside of the general annual spawning activity in the headwaters of the Kakisa River, the ecology of the population, including post-spawn habitat use and migratory patterns, remained understudied. To address these knowledge gaps, acoustic …
The Divine Invitation To Co-Creation: The Effects Of Creative Practice On The Vocation Of Clergy In The Anglican Church Of Canada, Dawn Dickieson-Leger
The Divine Invitation To Co-Creation: The Effects Of Creative Practice On The Vocation Of Clergy In The Anglican Church Of Canada, Dawn Dickieson-Leger
Theses and Dissertations (Comprehensive)
Creative practice has been confirmed as having benefits for health and well-being for people as well as an effective spiritual practice aiding in discernment. Clergy find their purpose in their sense of vocation, often formed and discerned in the context of seeking ordination. The researcher, an Anglican priest and amateur artist, presents a renewed idea of vocation as co-creation with God by engaging in creative practice. Throughout the dissertation she offers reflections from her own experiences in art, health recovery, and ministry. Fifteen Anglican clergy were interviewed about their vocation, ministry, and creative practice. Each of these clergy met the …
Marine And Freshwater Habitats Used By Sympatric Anadromous Arctic Char (Salvelinus Alpinus) And Dolly Varden (S. Malma Malma) In The Central Canadian Arctic, Simon W. Depasquale Mr.
Marine And Freshwater Habitats Used By Sympatric Anadromous Arctic Char (Salvelinus Alpinus) And Dolly Varden (S. Malma Malma) In The Central Canadian Arctic, Simon W. Depasquale Mr.
Theses and Dissertations (Comprehensive)
Two closely related but distinct species of char, Arctic Char (Salvelinus alpinus) and Dolly Varden (S. malma), are critically important to the food security and culture of Indigenous peoples in northern North America. Subsistence Inuit fishers in Kugluktuk, NU, Canada, have noticed changes in the timing and locations of their catches of char in the past ~ 10 years. In response, an ongoing partnered research program between the Kugluktuk Hunters and Trappers Organization (HTO) and scientists was formed to study Arctic Char and northern form Dolly Varden (S. malma malma). Char research near Kugluktuk presents a unique opportunity to further …
Weight Stigma In Health-Related Undergraduate Programs, Alicia Rodney
Weight Stigma In Health-Related Undergraduate Programs, Alicia Rodney
Theses and Dissertations (Comprehensive)
Health-related undergraduate programs are common pathways for future health care providers and play a critical role in shaping attitudes toward weight, as biases formed during training often carry over into professional practice. While weight stigma (WS) has been examined among practicing professionals and medical students, little is known about how it is experienced by undergraduate students in different health-related programs, particularly across the weight spectrum. This qualitative study contributes to closing this gap by exploring and comparing how students in one kinesiology and one health sciences program experience WS within an academic setting.
Using Reflexive Thematic Analysis, open-ended survey responses …
Integrating Indigenous Values And Community Strengths To Achieve Indigenous Food Sovereignty And Community Well-Being In The Ka’A’Gee Tu First Nation, Northwest Territories, Jennifer K. Temmer
Integrating Indigenous Values And Community Strengths To Achieve Indigenous Food Sovereignty And Community Well-Being In The Ka’A’Gee Tu First Nation, Northwest Territories, Jennifer K. Temmer
Theses and Dissertations (Comprehensive)
Northern Indigenous communities face disproportionate impacts from interconnected challenges related to climate change, food security, health, and cultural preservation, that threaten traditional food systems and practices. While there is a growing recognition of the importance of community-driven solutions, existing frameworks fail to integrate Indigenous values and local priorities effectively. This research addresses this gap by exploring how the Ka’a’gee Tu First Nation (KTFN) is responding to these crises through climate change adaptation efforts focused on food system sustainability as a pathway to self-sufficiency and community well-being. To contribute to these efforts, this dissertation uses Participatory Action Research to facilitate community-driven …
Gold Nanoparticle-Enhanced Molecularly Imprinted Polymer Electrode For Non-Enzymatic Lactate Sensing, Christopher Animashaun, Abdellatif Ait Lahcen, Gymama Slaughter
Gold Nanoparticle-Enhanced Molecularly Imprinted Polymer Electrode For Non-Enzymatic Lactate Sensing, Christopher Animashaun, Abdellatif Ait Lahcen, Gymama Slaughter
Center for Bioelectronics Publications
We are reporting the development of a high-performance, non-enzymatic electrochemical biosensor for selective lactate detection, integrating laser-induced graphene (LIG), gold nanoparticles (AuNPs), and a molecularly imprinted polymer (MIP) synthesized from poly(3,4-ethylenedioxythiophene) (PEDOT). The LIG electrode offers a highly porous, conductive scaffold, while electrodeposited AuNPs enhance catalytic activity and signal amplification. The PEDOT-based MIP layer, electropolymerized via cyclic voltammetry, imparts molecular specificity by creating lactate-specific binding sites. Cyclic voltammetry confirmed successful molecular imprinting and enhanced interfacial electron transfer. The resulting LIG/AuNPs/MIP biosensor demonstrated a wide linear detection range from 0.1 µM to 2500 µM, with a sensitivity of 22.42 µA/log(µM) and …
Development Of A Bean Cookbook To Assist Families With Low Income Utilize Legumes Provided In Nutrition Assistance Programs, Kira Moneke
Health and Nutritional Sciences Graduate Students Plan B Capstone Projects
Introduction: This project aimed to create a cookbook designed to help individuals receiving food assistance through programs like WIC, FDPIR, TEFAP, SNAP, and local food pantries, utilize beans, peas, and legumes in their meals. The focus was on providing easy, accessible recipes using six different types of beans to improve diet quality.
Methods: The cookbook was developed considering limited cooking skills, equipment, literacy, and time that may be barriers to preparing healthy food for low-income adults. Selected recipes were compiled into an educational cookbook.
Results: Recipes were tested and developed for six types of beans and aquafaba. …
Assessing The Prevalence Of Food Security Among South Dakotan Families Who Have Children With Disabilities, Erica Declark
Assessing The Prevalence Of Food Security Among South Dakotan Families Who Have Children With Disabilities, Erica Declark
Health and Nutritional Sciences Graduate Students Plan B Capstone Projects
Background
Almost 13% of U.S. families experienced food insecurity in 2022; i.e., an inability to acquire enough food to meet household members’ needs. Many factors can influence food security status, such as environmental conditions, social factors, and financial costs. Families with children who have disabilities may be at higher risk for food insecurity due to additional financial stressors related to these children’s care.
Purpose
The purpose of this study was to determine the prevalence of food insecurity among South Dakota families who have children with disabilities. We hypothesized that South Dakota families with children with disabilities are at an increased …
Out-Of-Pocket Healthcare Expenses Are Associated With Food Insecurity Among South Dakotan Families Who Have Children With Disabilities, Halie E. Kruid
Out-Of-Pocket Healthcare Expenses Are Associated With Food Insecurity Among South Dakotan Families Who Have Children With Disabilities, Halie E. Kruid
Health and Nutritional Sciences Graduate Students Plan B Capstone Projects
Background
In 2023, 17.9 percent (6.5 million) of households with children experienced household food insecurity, i.e., an inability to acquire enough food to meet household members’ needs. Many socioeconomic factors can influence food security status, such as environmental conditions, social factors, and financial costs. Families with children with disabilities (CWD) may be at higher risk for food insecurity due to additional financial stressors related to these children’s care.
Purpose
The purpose of this study was to determine the prevalence of food insecurity, as well as the medical and financial factors associated with an increased food insecurity prevalence, among South Dakota …
Myrtillin As A Promising Immunomodulator: Molecular Modeling And Pharmacokinetic Evaluation, Adolat Manakbayeva, Timur Kerimov, I D. Ershov, E. I. Anarkulova, Pavel Alexyuk, Y Moldakhanov, Ahdrey P. Bogoyavlenskiy, Vyacheslav Dushenkov
Myrtillin As A Promising Immunomodulator: Molecular Modeling And Pharmacokinetic Evaluation, Adolat Manakbayeva, Timur Kerimov, I D. Ershov, E. I. Anarkulova, Pavel Alexyuk, Y Moldakhanov, Ahdrey P. Bogoyavlenskiy, Vyacheslav Dushenkov
Publications and Research
Myrtillin, an anthocyanin found in blueberry fruits, is known for its antioxidant and potentially immunomodulatory properties. In this study, molecular docking was used to evaluate its interactions with a wide panel of immune-related proteins, including pro-inflammatory cytokines (TNF-α, IL-6, IL-17), antiinflammatory mediators (IL-4, IL-10), and signaling pathway proteins (1NFK, p52/RelB). The in silico results were supported by interaction analysis, and an ADMET analysis was conducted to assess the pharmacokinetic and toxicological profile. The findings confirm the promise of Myrtillin as a natural modulator of inflammatory responses.
Prisons Built On Toxic Sites: Eighth Amendment Protections For Pregnant Incarcerated Persons, Bianca Stockmeier
Prisons Built On Toxic Sites: Eighth Amendment Protections For Pregnant Incarcerated Persons, Bianca Stockmeier
Public Interest Law Reporter
No abstract provided.
Creating A Neonatal Intensive Care Unit Evidence Based Evaluation Protocol, Mary Redlin
Creating A Neonatal Intensive Care Unit Evidence Based Evaluation Protocol, Mary Redlin
Occupational Therapy Capstones
Background: Neonatal Intensive Care Units (NICU) in the United States admit approximately 300,000 infants annually (Valencia et al., 2023). Upon admission, neonatal occupational therapists assess a range of factors, including neurobehavioral, neuromotor, musculoskeletal, and sensory systems, as well as family/caregiver interactions and activities of daily living (Craig et al., 2018). This comprehensive evaluation underscores the need for effective assessment tools, efficient protocols, and adequate support for therapists. However, practitioners often face challenges that impact the quality of care, such as limited resources, lack of specialized training, and inconsistent organizational standards (Kaur et al., 2021). Occupational therapy has emerged as a …
Promoting Wellness In Community-Dwelling Older Adults: An Occupational Therapy Approach Guided By The Eight Dimensions Of Wellness, Mckenzie Ulrich
Promoting Wellness In Community-Dwelling Older Adults: An Occupational Therapy Approach Guided By The Eight Dimensions Of Wellness, Mckenzie Ulrich
Occupational Therapy Capstones
Background: Wellness is a process where an individual intentionally makes choices to support a satisfying lifestyle and is aware of their choices (Swarbrick & Yudof, 2015). In the United States, unhealthy lifestyle choices and the high prevalence of chronic conditions negatively influence one’s health, wellness, and quality of life (Li et al., 2018). Additionally, age-related changes can negatively influence one’s overall well-being. Examples of age-related changes may include changes in strength, mobility, coordination, balance, gait, and cognitive functioning (Bello-Haas et al., 2018a; Bello-Haas et al., 2018b; Judge & Dawson, 2018). Occupational therapy's role in health promotion and prevention includes promoting …