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Articles 8401 - 8430 of 10512
Full-Text Articles in Entire DC Network
Strength Training Can Modulate Urinary Adipokine Levels In Healthy Young Males, Marcelo Henrique Salviano De Faria, Lucélia Scarabeli Silva Barroso, Antonio Felipe Souza-Gomes, João Luís Vieira Monteiro De Barros, Adriana Maria Kakehasi, Erica Leandro Marciano Vieira, Ana Cristina Simões E Silva, Albená Nunes Silva
Strength Training Can Modulate Urinary Adipokine Levels In Healthy Young Males, Marcelo Henrique Salviano De Faria, Lucélia Scarabeli Silva Barroso, Antonio Felipe Souza-Gomes, João Luís Vieira Monteiro De Barros, Adriana Maria Kakehasi, Erica Leandro Marciano Vieira, Ana Cristina Simões E Silva, Albená Nunes Silva
International Journal of Exercise Science
International Journal of Exercise Science 18(2): 107-118, 2025. Adipose tissue stores energy in fat-rich adipocytes, which can produce and release several adipokines and modulate body metabolism. Exercise may induce adipokine production in adipocytes; however, the relationship between the two remains unclear. Few studies have shown the relationship between adipokines and strength training. Thus, we aimed to evaluate the acute and chronic effects of strength training (ST) on urinary adiponectin, leptin, and resistin levels. Twelve untrained young men (23.42 ± 2.67 years) were included in this study. Body composition was evaluated at baseline and after completing of the training protocol using …
Moving From ‘Managing Stakeholders’ To ‘Managing For Stakeholders’: The Imperative For Responsible Business, Meena Raghunathan, Kara Li Liu
Moving From ‘Managing Stakeholders’ To ‘Managing For Stakeholders’: The Imperative For Responsible Business, Meena Raghunathan, Kara Li Liu
Markets, Globalization & Development Review
Gone are the days when it was accepted that shareholders were the ones for whose benefit business was done, and that the purpose of business was to maximize returns to shareholders. Today, it is universally accepted that a business has to look beyond maximizing profits. It has to take into account the needs all stakeholders, including the environment.
Several frameworks and approaches have been advocated to achieve the objective of optimizing the value of the corporation from multiple angles, including Triple Bottom Line, Responsible Business, Sustainability, Corporate Social Responsibility, etc. At the heart of all these concepts is the issue …
Evaluation Of Green Tea Yoghurt Enriched With Lacticaseibacillus Paracasei E1 Microcapsules On Macrophage M1 Profile In High Fat-Fructose Diet Mice, Esha Ardiansyah, Nur Alfi Maghfirotus Sa’Adah, Rahmi Izati, Belinda Nabiila Al Faizah, Dawama Nur Fadlilah, Septhyanti Aprilia Kavitarna, Mochammad Fitri Atho’Illah, Siti Nur Arifah, Yoga Dwi Jatmiko, Muhaimin Rifa’I
Evaluation Of Green Tea Yoghurt Enriched With Lacticaseibacillus Paracasei E1 Microcapsules On Macrophage M1 Profile In High Fat-Fructose Diet Mice, Esha Ardiansyah, Nur Alfi Maghfirotus Sa’Adah, Rahmi Izati, Belinda Nabiila Al Faizah, Dawama Nur Fadlilah, Septhyanti Aprilia Kavitarna, Mochammad Fitri Atho’Illah, Siti Nur Arifah, Yoga Dwi Jatmiko, Muhaimin Rifa’I
Karbala International Journal of Modern Science
Obesity is caused by an energy imbalance that increases chronic low-grade inflammation, including macrophage cell infiltration. Adipose tissue macrophages are polarized into pro-inflammatory macrophage type 1 (M1), secrete large amounts of pro-inflammatory cytokines, and activate transcription factors. Yoghurt with probiotics is popular at all ages for its health benefits and must be protected by microencapsulation. Green tea (Camellia sinensis L.) fortification provides yoghurt nutrients while improving its functional qualities and bioactivity. This study aimed to evaluate the effect of microencapsulation of Lacticaseibacillus paracasei E1 in green tea yoghurt (GTY) on the profile of M1 macrophages in mice fed a …
The Utah Statesman, January 6, 2025, Utah State University
The Utah Statesman, January 6, 2025, Utah State University
The Utah Statesman
Weekly student newspaper of Utah State University in Logan.
Ada News - 01/06/2025, American Dental Association, Publishing Division
Ada News - 01/06/2025, American Dental Association, Publishing Division
ADA News
Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.
Why Open Educational Resources (Oer) Are A Game-Changer For College Students, Rasha Kawar
Why Open Educational Resources (Oer) Are A Game-Changer For College Students, Rasha Kawar
PREL 4316 Student Publications - Archive
This blog post, written by Rasha Kawar explores the transformative potential of Open Educational Resources (OER) in higher education. Discussing how OER offers significant cost savings by providing free, accessible textbooks and course materials, alleviating the financial pressures many students face. From a personal perspective, the author reflects on their own experiences with costly textbooks and the frustration of purchasing materials that ultimately went unused. The post highlights how OER enhances student engagement by offering customizable, up-to-date content that can be tailored to course objectives, ensuring more relevant and dynamic learning experiences. Additionally, the author emphasizes how OER can support …
Unh Receives Grant To Increase Local And Culture Foods For Manchester Schools, Robbin Ray
Unh Receives Grant To Increase Local And Culture Foods For Manchester Schools, Robbin Ray
Media Relations
No abstract provided.
Periodic Fever, Aphthous Stomatitis, Pharyngitis & Cervical Adenitis, Sonia P. Wheat
Periodic Fever, Aphthous Stomatitis, Pharyngitis & Cervical Adenitis, Sonia P. Wheat
Walden Dissertations and Doctoral Studies
The suffering of children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is well documented and includes diminished quality of life (QoL), emotional/behavioral problems, fatigue, food avoidance and school absenteeism. As an example of childhood adversity, and because the model of pediatric medical traumatic stress demonstrates traumatic responses do not always subside over time, this study examined the psychosocial health of PFAPA survivors post resolution. Using a quantitative, cross-sectional study design, the psychosocial well-being of PFAPA survivors was compared to children with persistent asthma and children without chronic illness or a history of medical trauma. Two validated parent-completed …
Perceptions And Preferences Of Virtual Health To Promote Exercise Among People With Physical Disabilities: An Exploratory Mixed Methods Study, Madison Mintz
All ETDs from UAB
People with physical disabilities and mobility limitations can greatly benefit from participating in a physically active lifestyle and adopting health-promoting strategies and behaviors. Benefits of physical activity include better sleep quality and quantity; decreased anxiety; weight loss or healthy weight maintenance; and maintained or increased balance, coordination, strength, and endurance, to name a few. However, rates of physical activity and exercise participation are disproportionate among people with disabilities (PWD). Current literature suggests a myriad of barriers and environmental inaccessibility as a leading cause of PWD not engaging or meeting physical activity guidelines. However, community-based, virtually-delivered programs have become dramatically available …
Association Of Hospitals’ Organizational Characteristics And Market Factors Offering Integrative Medicine Services To Adult Cancer Patients, Sanober Ajani
All ETDs from UAB
Integrative medicine (IM) plays an important role in cancer symptom management by providing patients with a range of non-pharmacological options to help manage the physical and emotional symptoms associated with cancer and its treatment. More patients are seeking IM services due in part to a more holistic or patient-centered approach to cancer care, alleviating side effects from cancer treatments, improving quality of life, and enhancing cancer treatment effectiveness. Although the demand for IM services is increasing, there is a gap in our knowledge regarding which cancer hospitals are providing IM programs and what services are offered within these programs. Therefore, …
Evaluating The Contributions Of Nutrition Knowledge And Food Skills As Predictors Of Dietary Behavior, Diet Competence, And Diet Autonomy In Pre-Hypertensive Rural And Micropolitan Dwelling African American Adults In Alabama, Mary Catherine Robertson Lawson
Evaluating The Contributions Of Nutrition Knowledge And Food Skills As Predictors Of Dietary Behavior, Diet Competence, And Diet Autonomy In Pre-Hypertensive Rural And Micropolitan Dwelling African American Adults In Alabama, Mary Catherine Robertson Lawson
All ETDs from UAB
Introduction: African American (AA) adults living in rural, Southeastern communities experience disproportionately high rates of obesity-related chronic diseases. Many factors contributing to this health disparity are related to negative Social Determinants of Health that have individual and community level impacts. Nutrition knowledge (NK) and food skills (FS) are forms of health literacy that have been understudied in rural-dwelling AA adults. Understanding their relationships with self-perceived diet competence, autonomy, motivations, as well as diet behaviors and health outcomes could inform the development of future health research and policy. Methods: A scoping review was conducted to identify key trends and information gaps …
Elucidating The Impact Of Ribosome Biogenesis On Breast Cancer, Amr Rafat Elhamamsy
Elucidating The Impact Of Ribosome Biogenesis On Breast Cancer, Amr Rafat Elhamamsy
All ETDs from UAB
Ribosome biogenesis, a complex and multi-step process that occurs predominantly in the nucleolus, plays a critical role in cellular function by mediating protein synthesis through the assembly of ribosomal RNAs (rRNAs) and ribosomal proteins into functional ribosomes. In cancer, dysregulation of this process is linked to the development of specialized ribosomes (onco-ribosomes) that support oncogenic translation programs, enhancing tumor progression and therapeutic resistance. This dissertation explores the interplay between ribosome biogenesis and cancer, focusing particularly on the role of RNA Polymerase I (RNA Pol I) activity under hypoxic conditions and rRNA modifications in breast cancer. My first study elucidates the …
Gateways, Barriers, And Facilitators To Opioid Use Treatment For Low-Income Pregnant And Postpartum Women In The State Of Alabama, Lindsey Allison Rice Bender
Gateways, Barriers, And Facilitators To Opioid Use Treatment For Low-Income Pregnant And Postpartum Women In The State Of Alabama, Lindsey Allison Rice Bender
All ETDs from UAB
Low income, pregnant and postpartum women who misuse opioids in the state of Alabama face potentially life-threatening challenges when seeking substance misuse treatment and recovery support services. Our study used an explanatory sequential mixed-methods approach to explore gateways, barriers, and facilitators to opioid use disorder (OUD) treatment for pregnant and postpartum women in the state of Alabama. Surveys from 32 pregnant and postpartum individuals and in-depth interviews with 15 pregnant and postpartum individuals (four pregnant, four 0-6 months postpartum, four 7-12 months postpartum and three 13-18 months postpartum) were used to identify gateways, barriers, and facilitators to OUD treatment. Our …
Vitamin D Receptor Signaling Antagonizes RorT Signaling To Reprogram Th17 Cells, Blake Frey
Vitamin D Receptor Signaling Antagonizes RorT Signaling To Reprogram Th17 Cells, Blake Frey
All ETDs from UAB
Vitamin D3 has long been associated with protection against a myriad of autoimmune diseases commonly linked to dysregulation of the T helper 17 (Th17) program. Th17 cells rely on the nuclear receptor (NR) RORγt as the master transcription factor for differentiation and function, establishing a metastate that can drive pro-inflammatory or alternative pathways depending on external cues. Vitamin D3 signals through another NR, the vitamin D receptor (VDR), to inhibit IL-17A in favor of the immunosuppressive cytokine IL-10; however, the precise mechanisms remain unclear. We developed a novel dual Vdr reporter and conditional knockout mouse model, and for the first …
Increasing The Knowledge, Awareness, And Readiness To Change Of Cultural Sensitivity Among Public Health College Students, Margaret Enlow
Increasing The Knowledge, Awareness, And Readiness To Change Of Cultural Sensitivity Among Public Health College Students, Margaret Enlow
All ETDs from UAB
This research examined if a lecture-based intervention increased the DEI knowledge, awareness, and readiness to change in undergraduate public health students. Topics included a systematic review of DEI activities in undergraduate public health classrooms/academic programs, determining reliability of an adapted tool to measure knowledge, awareness, and readiness to change, and statistical analyses of pre- and post-data to determine knowledge, awareness, and readiness to change after students participated in the lecture-based intervention. The systematic review identified a gap in the literature regarding public health DEI education in the classroom. Through additional analyses, themes of DEI were identified in previous publications that …
Exploring Nutritional Needs In Spinal Cord Injury: Dietitian Perspectives, Bowel Health, And Dietary Recommendations, Ayse Gul Zengul
Exploring Nutritional Needs In Spinal Cord Injury: Dietitian Perspectives, Bowel Health, And Dietary Recommendations, Ayse Gul Zengul
All ETDs from UAB
Spinal cord injury (SCI) is a global condition affecting millions of people and leading to life-altering health complications. It profoundly alters body composition and metabolic rate, which need to be addressed with SCI-specific nutritional strategies. Muscle atrophy, fat accumulation, and decreased energy expenditure often lead to secondary health complications such as chronic diseases and SCI-related health problems, including pressure injuries and bowel dysfunction. Although nutrition plays a critical role in SCI management, our understanding of specific dietary needs for this population remains incomplete. This dissertation aims to comprehensively investigate the nutritional challenges and needs of individuals with SCI, ultimately developing …
Effects Of Whole-Food, Plant-Centered Diets On Glycemic Control, Medication Use, Ectopic Fat, And Cardiovascular Health In Adults With Type 2 Diabetes, Cody Hanick
All ETDs from UAB
Type 2 diabetes (T2D) is a global health and economic concern. Safe and effective treatments for T2D, including dietary approaches, are limited. Additionally, it remains unclear whether dietary carbohydrate quality or quantity matters more for managing T2D. Most nutrient-dense carbohydrate quality sources—such as fruit, vegetables, legumes, and whole grains—come from plant foods and are recommended for people with T2D by the American Diabetes Association. Furthermore, when these food groups are combined into a dietary pattern, a whole-food, plant-based (WFPB) diet is created. However, few studies have tested the effects of a WFPB diet or carbohydrate-rich food groups in people with …
Land-Use Effects On Soil Organic Matter And Related Soil Properties In A Mixed Agricultural–Forest Landscape Of Central Wisconsin, Usa, Kathryn L. Hofmeister, Gwen Feitl, Kaylee Tackett, Leah Fleury, Lucas E. Nave
Land-Use Effects On Soil Organic Matter And Related Soil Properties In A Mixed Agricultural–Forest Landscape Of Central Wisconsin, Usa, Kathryn L. Hofmeister, Gwen Feitl, Kaylee Tackett, Leah Fleury, Lucas E. Nave
Michigan Tech Publications
Soil organic matter (SOM) influences a wide range of ecosystem processes, including nutrient cycling, water movement, plant productivity, and biodiversity. In agricultural landscapes, adjacent land uses often differ in SOM contents and related soil properties, such as soil organic carbon (SOC) stocks, but the direction and magnitude of these effects are inconsistent across studies. We assessed how land uses differed in SOM and related properties in a representative US Midwest agricultural–forest landscape to support land-use and management decisions by local landowners and producers. We measured SOM, bulk density (Db), root biomass, and pH, and estimated SOC stocks, in a Typic …
Periodic Fever, Aphthous Stomatitis, Pharyngitis & Cervical Adenitis, Sonia P. Wheat
Periodic Fever, Aphthous Stomatitis, Pharyngitis & Cervical Adenitis, Sonia P. Wheat
Walden Dissertations and Doctoral Studies
The suffering of children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is well documented and includes diminished quality of life (QoL), emotional/behavioral problems, fatigue, food avoidance and school absenteeism. As an example of childhood adversity, and because the model of pediatric medical traumatic stress demonstrates traumatic responses do not always subside over time, this study examined the psychosocial health of PFAPA survivors post resolution. Using a quantitative, cross-sectional study design, the psychosocial well-being of PFAPA survivors was compared to children with persistent asthma and children without chronic illness or a history of medical trauma. Two validated parent-completed …
Myo5b And The Polygenic Landscape Of Very Early-Onset Inflammatory Bowel Disease In An Ethnically Diverse Population, Ashleigh Watson, R Alan Harris, Amy C Engevik, Numan Oezguen, Maribeth R Nicholson, Sarah Dooley, Rachel Stubler, Lisa Forbes Satter, Lina B Karam, Richard Kellermayer
Myo5b And The Polygenic Landscape Of Very Early-Onset Inflammatory Bowel Disease In An Ethnically Diverse Population, Ashleigh Watson, R Alan Harris, Amy C Engevik, Numan Oezguen, Maribeth R Nicholson, Sarah Dooley, Rachel Stubler, Lisa Forbes Satter, Lina B Karam, Richard Kellermayer
Faculty, Staff and Students Publications
Background: Genetic discovery in very early-onset inflammatory bowel disease (VEO-IBD) can elucidate not only the origins of VEO-IBD, but also later-onset inflammatory bowel disease. We aimed to investigate the polygenic origins of VEO-IBD in a cohort with a high proportion of Hispanic patients.
Methods: Patients with VEO-IBD who underwent whole exome sequencing at our center were included. Genes were categorized as genes of interest (GOIs) (129 genes previously described to be associated with VEO-IBD) or non-GOIs. VEO-IBD "susceptibility" single nucleotide variants (SNVs) were identified through enrichment compared with gnomAD (Genome Aggregation Database) and ALFA (Allele Frequency Aggregator) and were scored …
Potential Of Native Tree Species For Post-Nickel Mining Land Restoration, Fadly Suhati, Putu Oka Ngakan, Risma Illa Maulany, Nasri Nasri, Andi Siady Hamzah, Putu Supadma Putra
Potential Of Native Tree Species For Post-Nickel Mining Land Restoration, Fadly Suhati, Putu Oka Ngakan, Risma Illa Maulany, Nasri Nasri, Andi Siady Hamzah, Putu Supadma Putra
Jurnal Penelitian Kehutanan Wallacea
Due to the absence of topsoil, low pH, and contamination by various heavy metals, revegetation of post-nickel mining land, which is generally carried out by planting economically valuable species, is usually unsuccessful. This study aims to identify tree species suitable for revegetation on post-nickel mining land in Kolaka Regency, Indonesia. Nine plots measuring 20 m x 20 m were distributed in the revegetated post-nickel mining land at three different age categories (1, 5, and 10 years) to observe the growth of revegetation trees, which are introduced species and native tree species that naturally invade the revegetation area. In total, there …
Dietary Program For The Reduction Of Type 2 Diabetes Prevalence In A South Texas Border Region, Siddiqua Noor
Dietary Program For The Reduction Of Type 2 Diabetes Prevalence In A South Texas Border Region, Siddiqua Noor
Doctor of Nursing Practice Final Project Abstract
PURPOSE The purpose of this project was to create a culturally sensitive dietary program template to serve as a guide to offer healthier food alternatives to reduce the incidence of type 2 diabetes while not compromising on their Hispanic heritage.
BACKGROUND This project was implemented in a South Texas border community which has nearly twice the national average of Type 2 Diabetes Mellitus, which presents a significant public health challenge.
METHODOLOGY The project followed the Plan-Do-Study-Act cycle and incorporated the Health Belief Model. A dietary pamphlet featuring local culturally relevant food options was developed. The material was presented at two …
From The Skippers Line To The School Meal Queue: The Journey Of The Plymouth Fish Finger (So Far), Clare Pettinger, Louise Hunt, Laura Dunn, Star Drew, Carol Wagstaff, Rosie Tsikritzi, Caroline Bennett, Ed Baker
From The Skippers Line To The School Meal Queue: The Journey Of The Plymouth Fish Finger (So Far), Clare Pettinger, Louise Hunt, Laura Dunn, Star Drew, Carol Wagstaff, Rosie Tsikritzi, Caroline Bennett, Ed Baker
School of Health Professions
Informed by several community action research workshops, the FoodSEqual Plymouth team identified fish as a food commodity for innovation to inform food system transformation. This culminated in ‘The Plymouth Fish Finger’ – a co-designed food product that is healthy and sustainable, making use of locally procured fish that would otherwise be discarded and giving fishers a fair price for normally low-value by catch. It is being piloted with a view to getting it into the local school meal system, both as a product and an educational piece.This poster will share findings and creative collaborative processes of the Fish Finger pilot …
Severe Hypercalcemia Following Hip Joint Implantation Of Calcium Sulfate Antibiotic Beads: Case Series And Review Of Literature., Andrew P. Demidowich, Mahsa Motevalli, Kevin Yi, Atena Kamali, Kristine Batty, Kendall F. Moseley, Robert Raymond Buber, Mehdi Hashemipour`, Mihail Zilbermint
Severe Hypercalcemia Following Hip Joint Implantation Of Calcium Sulfate Antibiotic Beads: Case Series And Review Of Literature., Andrew P. Demidowich, Mahsa Motevalli, Kevin Yi, Atena Kamali, Kristine Batty, Kendall F. Moseley, Robert Raymond Buber, Mehdi Hashemipour`, Mihail Zilbermint
Journal of Community Hospital Internal Medicine Perspectives
Purpose: The diagnosis and management of hypercalcemia in hospitalized patients can be challenging. Hypercalcemia is often associated with significant morbidity and end-organ damage which may delay a patient’s recovery.
Methods: We report a case series of three patients who underwent orthopedic procedures with intraoperative placement of vancomycin-loaded calcium sulfate beads. Patients had no known history of malignancy or excess intake of calcium, vitamin A or vitamin D. Laboratory workup showed low parathyroid (PTH) levels and normal PTH-related peptide levels. The temporal nature of the non-PTH mediated hypercalcemia in relation to implantation of the antibiotic beads suggests causality of exogenous calcium …
Rapid Neurological Decline Due To Creutzfeldt-Jakob Disease, Nicole Tesoro, David Blackwood, Robert Reif, Samuel Miller, Kalyan Paudel, Christopher Haas
Rapid Neurological Decline Due To Creutzfeldt-Jakob Disease, Nicole Tesoro, David Blackwood, Robert Reif, Samuel Miller, Kalyan Paudel, Christopher Haas
Journal of Community Hospital Internal Medicine Perspectives
Creutzfeldt-Jakob Disease (CJD) is an exceedingly rare condition with an incidence of one case per million people worldwide. It is diagnosed with symptoms of rapid neurological decline, positive CSF biomarkers, and diagnostic findings on MRI and EEG. There is no known effective therapy for CJD and prompt diagnosis is required to prepare for the expected disease prognosis and goals of care discussions.
Primary Raynaud’S Phenomenon, Eliana Alweis, Richard Alweis
Primary Raynaud’S Phenomenon, Eliana Alweis, Richard Alweis
Journal of Community Hospital Internal Medicine Perspectives
The authors present a clinical image of primary Raynaud's phenomenon and briefly review its pathophysiology, differential diagnosis, and need for longitudinal follow up.
Mafld: Exploring The Systemic Effects Beyond Liver., Utkarsh Dayal, Ujjwal Soni, Sourav Bansal, Kanishk Aggarwal, Chaitanya Chennupati, Sai Gautham Kanagala, Vasu Gupta, Ripudaman Singh Munjal, Rohit Jain
Mafld: Exploring The Systemic Effects Beyond Liver., Utkarsh Dayal, Ujjwal Soni, Sourav Bansal, Kanishk Aggarwal, Chaitanya Chennupati, Sai Gautham Kanagala, Vasu Gupta, Ripudaman Singh Munjal, Rohit Jain
Journal of Community Hospital Internal Medicine Perspectives
Metabolic dysfunction-associated fatty liver disease (MAFLD) is a growing global health concern which is driven by the increasing prevalence of diabetes and obesity. MAFLD is characterized by excessive fat accumulation in the liver, which encompasses a range of conditions, from simple hepatic steatosis to more severe forms. This condition is associated with various complications, including chronic kidney disease (CKD), Cardiovascular Disease (CVD), liver cirrhosis, and even malignancy. Recent research has highlighted a potential connection between gut dysbiosis and MAFLD, particularly in relation to CKD. This has underscored the significance of the gut-liver-kidney axis in understanding MAFLD's pathogenesis. Inflammation triggered by …
Eng 1000-002 College Composition Studio, Ashley Flach
Predictive Value Of Fdg Uptake On Pet For Future Immune Checkpoint Inhibitor-Mediated Colitis: A Case Series, Malek Shatila, Kei Takigawa, Yang Lu, Andres Caleb Urias Rivera, Nitish Mittal, Abdullah Sagar Aleem, Sean Ngo, Eric Lu, Deanna Wu, Gabriel Sperling, Sidra Naz, Bryan Schneider, Anusha Shirwaikar Thomas, Yinghong Wang
Predictive Value Of Fdg Uptake On Pet For Future Immune Checkpoint Inhibitor-Mediated Colitis: A Case Series, Malek Shatila, Kei Takigawa, Yang Lu, Andres Caleb Urias Rivera, Nitish Mittal, Abdullah Sagar Aleem, Sean Ngo, Eric Lu, Deanna Wu, Gabriel Sperling, Sidra Naz, Bryan Schneider, Anusha Shirwaikar Thomas, Yinghong Wang
Faculty, Staff and Student Publications
Objectives: Immune-mediated colitis (IMC) is a common immune-related adverse event during immune checkpoint inhibitor (ICI) therapy. This case series and review aimed to highlight atypical cases of IMC and explore the potential of PET/CT to predict imminent ICI colitis.
Methods: Through a descriptive, retrospective study at a tertiary cancer center, we identified adult patients receiving ICIs for any cancer between 2010 and 2022 who also underwent PET/CT for routine cancer surveillance during this time. We included patients who had signs and symptoms of colitis and reviewed their surveillance PET/CT scans obtained 2 to 6 weeks before and up to 3 …
Potential Of Red Ginger Rhizome (Zingiber Officinale Roscoe Var. Rubrum) As An Anti-Cancer: A Review, I Gede Yudi Anggara, Aguslina Kirtishanti, Marisca E. Gondokesumo
Potential Of Red Ginger Rhizome (Zingiber Officinale Roscoe Var. Rubrum) As An Anti-Cancer: A Review, I Gede Yudi Anggara, Aguslina Kirtishanti, Marisca E. Gondokesumo
Pharmacology and Clinical Pharmacy Research
Red ginger rhizome, Zingiber officinale Roscoe var. Rubrum has long been used as a herbal medicine. Its biological properties, including anti-cancer properties, are confirmed. Compared to their stems and leaf tissues, the average amount of gingerols in red ginger rhizomes (104.39 μg/g) is much higher. In addition to gingerol, other nonvolatile pungent chemicals found in ginger include shogaols, paradols, gingerdiols, and zingerone. Gingerol disrupts the cell cycle, triggers apoptosis in cancer cells, and prevents the growth and spread of cells by interacting with particular proteins, gene targets, and signal transduction pathways. 6-shogaol activity suppresses NF-kB and signal transducer and activator …