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2025

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Big Data Management Within Multi-Objective Optimization Modeling For Sustainable Food Production, Breanna Paige Modica Jan 2025

Big Data Management Within Multi-Objective Optimization Modeling For Sustainable Food Production, Breanna Paige Modica

Walden Dissertations and Doctoral Studies

Producing enough food to feed a growing human population without further degrading the environment through unsustainable natural resource use is a global issue. The purpose of this quantitative nonexperimental study was to examine the extent to which big data management of environmental impact sources, assessment methods, and allocation methods in multi-objective optimization (MOO) modeling affect the consistency and predictability of sustainable food animal feed management practices at the farm level. Representation theory, the theory of effective use of information systems, the dynamic capabilities view, and the natural resource-based view were used to describe the necessity of accurately representing and managing …


Economic Impact And Clinical Benefits Of Clinical Pharmacy Interventions: A Six-Year Multi-Center Study Using An Innovative Medication Management Tool, Watheq M. Alsetohy, Kareem A. El-Fass, Seif El Hadidi, Mohammad F. Zaitoun, Osama Badary, Kareem Ali, Ahmed Ezz-Elden, Mohamed R. Ibrahim, Bahaa S. Makhlouf, Asmaa Hamdy, Noha S. El Baghdady, Maha Gamal Eldien, Sherif Allama, Amr A. Alashkar, Ahmed Seyam, Nanees Adel, Ahmed R. N. Ibrahim, Hany V. Zaki Jan 2025

Economic Impact And Clinical Benefits Of Clinical Pharmacy Interventions: A Six-Year Multi-Center Study Using An Innovative Medication Management Tool, Watheq M. Alsetohy, Kareem A. El-Fass, Seif El Hadidi, Mohammad F. Zaitoun, Osama Badary, Kareem Ali, Ahmed Ezz-Elden, Mohamed R. Ibrahim, Bahaa S. Makhlouf, Asmaa Hamdy, Noha S. El Baghdady, Maha Gamal Eldien, Sherif Allama, Amr A. Alashkar, Ahmed Seyam, Nanees Adel, Ahmed R. N. Ibrahim, Hany V. Zaki

Pharmacy

Background

Increasing healthcare costs, particularly in Low- and Middle-Income Countries (LMICs) like Egypt, highlight the need for rational economic strategies. Clinical pharmacy interventions offer potential benefits by reducing drug therapy problems and associated costs, thereby supporting healthcare system sustainability.

Objective

This study evaluates the economic impact and clinical benefits of clinical pharmacy interventions in four tertiary hospitals in Egypt by implementing an innovative tool for medication management, focusing on cost avoidance and return on investment (ROI), while accounting for case severity and drug therapy problem (DTP) resolution.

Methods

Utilizing a digital tool, cost avoidance was assessed by considering the severity …


Perceptions And Practices Of Imaging Personnel And Physicians Regarding The Use Of Brain Mri For Dementia Diagnosis In Uganda, Stephen E. Jones, Martha Sajatovic Jan 2025

Perceptions And Practices Of Imaging Personnel And Physicians Regarding The Use Of Brain Mri For Dementia Diagnosis In Uganda, Stephen E. Jones, Martha Sajatovic

Faculty Scholarship

Introduction Diagnosing dementia remains challenging in low-income settings due to limited diagnostic options and the absence of definitive biomarkers. The use of brain MRI in the diagnosis of dementia is infrequent in Uganda, and even when it is used, subtle findings like mild regional atrophy are often overlooked, despite being crucial for imaging diagnosis. Objective The purpose of this study was to explore the perceptions and practices of imaging personnel and physicians regarding the use of brain MRI as a diagnostic approach for dementia in Uganda. Methods This was an exploratory qualitative study involving radiologists, technologists, senior house officers and …


Big Data Management Within Multi-Objective Optimization Modeling For Sustainable Food Production, Breanna Paige Modica Jan 2025

Big Data Management Within Multi-Objective Optimization Modeling For Sustainable Food Production, Breanna Paige Modica

Walden Dissertations and Doctoral Studies

Producing enough food to feed a growing human population without further degrading the environment through unsustainable natural resource use is a global issue. The purpose of this quantitative nonexperimental study was to examine the extent to which big data management of environmental impact sources, assessment methods, and allocation methods in multi-objective optimization (MOO) modeling affect the consistency and predictability of sustainable food animal feed management practices at the farm level. Representation theory, the theory of effective use of information systems, the dynamic capabilities view, and the natural resource-based view were used to describe the necessity of accurately representing and managing …


Dysregulated Klf4 Expression Plays A Pivotal Role In The Pathogenesis Of Pancreatic Intraductal Papillary Mucinous Neoplasms, Xiangsheng Zuo, Liang Wang, Yi Liu, Huamin Wang, Margarete Hafley, Mihai Gagea, Ru Chen, Yun Xiong, Sheng Pan, Imad Shureiqi, Robert S Bresalier, Daoyan Wei Jan 2025

Dysregulated Klf4 Expression Plays A Pivotal Role In The Pathogenesis Of Pancreatic Intraductal Papillary Mucinous Neoplasms, Xiangsheng Zuo, Liang Wang, Yi Liu, Huamin Wang, Margarete Hafley, Mihai Gagea, Ru Chen, Yun Xiong, Sheng Pan, Imad Shureiqi, Robert S Bresalier, Daoyan Wei

Faculty, Staff and Student Publications

No abstract provided.


Light-Dark Shift Promotes Colon Carcinogenesis Through Accelerated Colon Aging, Deepak Sharma, Phillip A Engen, Abu Osman, Darbaz Adnan, Maliha Shaikh, Mostafa K Abdel-Reheem, Ankur Naqib, Stefan J Green, Bruce Hamaker, Christopher B Forsyth, Lin Cheng, Ali Keshavarzian, Khashayarsha Khazaie, Faraz Bishehsari Jan 2025

Light-Dark Shift Promotes Colon Carcinogenesis Through Accelerated Colon Aging, Deepak Sharma, Phillip A Engen, Abu Osman, Darbaz Adnan, Maliha Shaikh, Mostafa K Abdel-Reheem, Ankur Naqib, Stefan J Green, Bruce Hamaker, Christopher B Forsyth, Lin Cheng, Ali Keshavarzian, Khashayarsha Khazaie, Faraz Bishehsari

Faculty, Staff and Student Publications

Colorectal cancer (CRC) is the third most common cancer worldwide, with rising prevalence among younger adults. Several lifestyle factors, particularly disruptions in circadian rhythms by light-dark (LD) shifts, are known to increase CRC risk. Epidemiological studies previously showed LD-shifts are associated with increased risk of CRC. To explore the mechanisms and interactions between LD-shift and intestinal aging, we investigated how the combination of LD-shifts and aging impacts colon carcinogenesis development. Our data showed that LD-shifts and aging increased colon tumorigenesis. Notably, LD-shift accelerated intestinal aging by altering aging-related pathways, such as intestinal barrier damage, accompanied by dysbiotic changes in the …


Recommendations For Interdisciplinary Research Collaboration For Early Career Dissemination And Implementation Researchers: A Multi-Phase Study, Hannah G Lane, Sallie D Allgood, Julie Schexnayder, Hayden B Bosworth, Ana A Baumann, Allison A Lewinski Jan 2025

Recommendations For Interdisciplinary Research Collaboration For Early Career Dissemination And Implementation Researchers: A Multi-Phase Study, Hannah G Lane, Sallie D Allgood, Julie Schexnayder, Hayden B Bosworth, Ana A Baumann, Allison A Lewinski

2020-Current year OA Pubs

INTRODUCTION: Dissemination and implementation (D&I) scientists are key members of collaborative, interdisciplinary clinical and translational research teams. Yet, early career D&I researchers (ECRs) have few guidelines for cultivating productive research collaborations. We developed recommendations for ECRs in D&I when serving as collaborators or co-investigators.

METHODS: We employed a consensus-building approach: (1) group discussions to identify 3 areas of interest: "Marketing yourself" (describing your value to non-D&I collaborators), "Collaboration considerations

RESULTS: Forty-four D&I researchers completed the first survey, 12 of whom attended one of three focus groups. Twenty-nine D&I researchers completed the second survey (

CONCLUSIONS: Research collaborations are essential in …


Food Marketing To Youth, Marlene Schwartz, Dale Kunkel, Sarah Delucia Jan 2025

Food Marketing To Youth, Marlene Schwartz, Dale Kunkel, Sarah Delucia

Communication Research Trends

No abstract provided.


A Comparative Study Of Leadership Styles Of U.S. Olympic Swimming Head Coaches, Stephanie Barnes Jan 2025

A Comparative Study Of Leadership Styles Of U.S. Olympic Swimming Head Coaches, Stephanie Barnes

Masters Theses

The role of leadership is paramount in successful sport coaching. The current study explored the realm of coaching in swimming to gain a deeper understanding of the unique and diverse leadership styles of U.S. Olympic Head Swimming Coaches. This study employed a qualitative phenomenological research design using a case study approach with two specific cases. Purposeful sampling was utilized to investigate two former U.S. Olympic Head Swimming Coaches with a combined 80 years of elite professional swim coach experience. Through semi-structured interviews and detailed questions, meaningful insight was gained into coaching practices, athlete interactions, and self-perceived effectiveness. Data analysis utilizing …


Hiv Associated Epigenetic Trends And Chronic Diseases: Insights Into The Hidden Burden Of Chronic Infection, Courtney G. Wallace, Zachary Capriotti, Zachary Klase Jan 2025

Hiv Associated Epigenetic Trends And Chronic Diseases: Insights Into The Hidden Burden Of Chronic Infection, Courtney G. Wallace, Zachary Capriotti, Zachary Klase

Kimmel Cancer Center Faculty Papers

Human Immunodeficiency Virus (HIV) remains a major health challenge despite dramatic advances in treatment and prevention. People living with HIV (PLWH) continue to experience high rates of non-AIDS comorbidities, including cardiovascular, renal, pulmonary, oncologic, and neurocognitive disorders. These conditions persist under viral suppression, underscoring the lasting biological impact of infection. Epigenetic dysregulation has emerged as a key driver of these outcomes. HIV integration, viral proteins, chronic inflammation, and ART exposure have all been reported to alter DNA methylation, histone modifications, transcription factor networks, and noncoding RNA regulation. These changes extend beyond infected cells, reprogramming uninfected immune and tissue compartments. Long-lived …


Improving Cooking Skills, Lifestyle Behaviors, And Clinical Outcomes For Adults At Risk For Cardiometabolic Disease: Protocol For A Randomized Teaching Kitchen Multisite Trial (Tk-Mt), Jennifer Massa, Candace Sapp, Kate Janisch, Mopelola A Adeyemo, Auden Mcclure, Natalia I Heredia, Deanna M Hoelscher, Tannaz Moin, Shaista Malik, Wendelin Slusser, David M Eisenberg Jan 2025

Improving Cooking Skills, Lifestyle Behaviors, And Clinical Outcomes For Adults At Risk For Cardiometabolic Disease: Protocol For A Randomized Teaching Kitchen Multisite Trial (Tk-Mt), Jennifer Massa, Candace Sapp, Kate Janisch, Mopelola A Adeyemo, Auden Mcclure, Natalia I Heredia, Deanna M Hoelscher, Tannaz Moin, Shaista Malik, Wendelin Slusser, David M Eisenberg

Faculty, Staff and Student Publications

BACKGROUND/OBJECTIVES: This protocol describes a study to investigate the feasibility and preliminary efficacy of a novel Teaching Kitchen Multisite Trial (TK-MT) for adults with cardiometabolic abnormalities. The TK-MT protocol describes a hybrid lifestyle intervention combining in-person and virtual instruction in culinary skills, nutrition education, movement, and mindfulness with community support and behavior change strategies. This 18-month-long randomized controlled trial aims to evaluate the feasibility of implementing a 12-month, 24 class program, assess preliminary study efficacy, and identify barriers and facilitators to implementation.

METHODS: The intervention program includes 16 weeks of intensive hands-on culinary and lifestyle education classes followed by eight …


Current Status Of Hemodialysis In Iraq, Ismael Ismael, Anas Khalaf, Dalia Ali, Ali Al Saedi Jan 2025

Current Status Of Hemodialysis In Iraq, Ismael Ismael, Anas Khalaf, Dalia Ali, Ali Al Saedi

Iraqi National Journal of Medicine

Background: The progressive and permanent damage associated with chronic kidney disease (CKD) makes it a major global health concern. Hemodialysis (HD) is a vital renal replacement therapy; however, its prevalence and adequacy remain understudied in Iraq. Aim: This study aims to assess the current situation of HD in Iraq, focusing on the prevalence and causes of CKD. Patients and Methods: This cross-sectional study included all Iraqi cities and examined patients receiving HD from January 1 to December 31, 2023. Data was collected through a structured questionnaire at governorate centers across Iraq. Results: A total of 10,721 HD patients from various …


Keeping Kids Safe At Meals: Preventing And Responding To Choking, Mia Dustin, Savannah Daines, Stacy Bevan, Palak Gupta, Mateja R. Savoie-Roskos Jan 2025

Keeping Kids Safe At Meals: Preventing And Responding To Choking, Mia Dustin, Savannah Daines, Stacy Bevan, Palak Gupta, Mateja R. Savoie-Roskos

All Current Publications

Introducing solid foods is an exciting developmental milestone, but it can also raise concerns about choking for parents and caregivers. Choking occurs when an object, such as food or a toy, blocks a child’s airway and prevents air from moving in and out of the lungs. This fact sheet offers practical guidance on how to prevent food-related choking, recognize the signs of a choking emergency, and what to do if a child is choking.


A Phenomenological Study Exploring The Lived Experiences Of Former Adult Drug Users’ Sobriety Journey After Graduating From A Faith-Based/Spiritual Drug And Alcohol Recovery Program, Laurine Voltaire Jan 2025

A Phenomenological Study Exploring The Lived Experiences Of Former Adult Drug Users’ Sobriety Journey After Graduating From A Faith-Based/Spiritual Drug And Alcohol Recovery Program, Laurine Voltaire

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to investigate the lived experiences of former adult drug users and their sobriety journeys after graduating from a variety of faith-based or spiritual drug and alcohol recovery programs. The research included a systematic review and narrative synthesis of existing literature on faith-based and spiritual recovery programs to address the gap concerning the lived experiences of former users and an evaluation of the strategies and techniques vital for facilitating recovery. The guiding theoretical framework CHIME-D delineated the essential definitive characteristics such as connectedness, hope, identity, meaning of life, empowerment, and overcoming difficulties that …


Sex Differences In Response To Diet Enriched With Glutathione Precursors In The Aging Heart, Aude Angelini, Grecia Garcia Marquez, Anna Malovannaya, Marta L Fiorotto, Alexander Saltzman, Antrix Jain, Joann Trial, George E Taffet, Katarzyna A Cieslik Jan 2025

Sex Differences In Response To Diet Enriched With Glutathione Precursors In The Aging Heart, Aude Angelini, Grecia Garcia Marquez, Anna Malovannaya, Marta L Fiorotto, Alexander Saltzman, Antrix Jain, Joann Trial, George E Taffet, Katarzyna A Cieslik

Faculty, Staff and Students Publications

Common features of the aging heart are dysregulated metabolism, inflammation, and fibrosis. Elevated oxidative stress is another hallmark of cardiac aging that can exacerbate each of these conditions. We hypothesize that by increasing natural antioxidant levels (glutathione), we will improve cardiac function. Twenty-one-month-old mice were fed glycine and N-acetyl cysteine (GlyNAC; glutathione precursors)-supplemented or control diets for 12 weeks. Heart function was monitored longitudinally, and the exercise performance was determined at the end of the study. We found that the GlyNAC diet was beneficial for old male but not old female mice, leading to an increase of Ndufb8 expression (a …


Synesis As A Framework To Enable Safety Interventions In Complex Healthcare Environments, Aarti Bavare, Tiffany Wrenn, Anne Lam, Jamie Cargill, Lauren Salinas, Itode Idowu, Asma Razavi, Venessa Lynn Pinto, Eric Williams Jan 2025

Synesis As A Framework To Enable Safety Interventions In Complex Healthcare Environments, Aarti Bavare, Tiffany Wrenn, Anne Lam, Jamie Cargill, Lauren Salinas, Itode Idowu, Asma Razavi, Venessa Lynn Pinto, Eric Williams

Faculty, Staff and Students Publications

BACKGROUND: Despite wide adoption in the healthcare of safety event report (SER) systems, there is a paucity of unified structures for prompt analysis and action while retaining reporter confidentiality. We used a synesis framework to change siloed reviews of safety reports to a comprehensive appraisal of quality, safety, productivity and reliability to facilitate interventions.

METHODS: After a needs assessment survey, we launched serial plan-do-study-act cycles to (1) enhance teams' ability to access SERs, (2) facilitate regular multidisciplinary review of SERs to identify actionable opportunities, (3) allocate action priority using failure mode and effects analysis, and (4) launch actions and summarise …


Associations Between Deficit Accumulation Frailty And Baseline Markers Of Lifestyle In The Us Pointer Trial, Mark A Espeland, Yitbarek N Demesie, Kayloni Olson, Samuel N Lockhart, Sarah E Tomaszewski Farias, Maryjo L Cleveland, Christy C Tangney, Lucia Crivelli, Heather M Snyder, Michele K York, Laura D Baker, Rachel A Whitmer, Rena R Wing, Katelyn R Garcia, Kathryn E Callahan Jan 2025

Associations Between Deficit Accumulation Frailty And Baseline Markers Of Lifestyle In The Us Pointer Trial, Mark A Espeland, Yitbarek N Demesie, Kayloni Olson, Samuel N Lockhart, Sarah E Tomaszewski Farias, Maryjo L Cleveland, Christy C Tangney, Lucia Crivelli, Heather M Snyder, Michele K York, Laura D Baker, Rachel A Whitmer, Rena R Wing, Katelyn R Garcia, Kathryn E Callahan

Faculty, Staff and Students Publications

BACKGROUND: Multidomain lifestyle interventions may have the potential to slow biological aging as captured by deficit accumulation frailty indices. We describe the distribution and composition of the 49-component frailty index developed by the U.S. POINTER clinical trial team of investigators and assess its cross-sectional associations with sociodemographic factors and markers chosen to be representative of behaviors targeted by the trial's multidomain interventions.

METHODS: We draw baseline data from the 2 111 volunteers enrolled in U.S. POINTER who were ages 60-79 years and at increased risk for cognitive decline. Frailty components were grouped into 9 domains. Associations that frailty index scores …


Gatekeeping Theory From Social Fields To Social Networks, David Deiuliis Jan 2025

Gatekeeping Theory From Social Fields To Social Networks, David Deiuliis

Communication Research Trends

No abstract provided.


Eng 4801-001 Integrating The English Language, Elizabeth Tacke Jan 2025

Eng 4801-001 Integrating The English Language, Elizabeth Tacke

Spring 2025

No abstract provided.


Eng 4903z-600 Young Adult Literature, Niall Nance-Carroll Jan 2025

Eng 4903z-600 Young Adult Literature, Niall Nance-Carroll

Spring 2025

No abstract provided.


Eng 1002g-015 College Composition Ii, Glen Davis Jan 2025

Eng 1002g-015 College Composition Ii, Glen Davis

Spring 2025

No abstract provided.


Eng 1001g-010 College Composition I Critical Reading & Source Based Writing, Niall Nance-Carroll Jan 2025

Eng 1001g-010 College Composition I Critical Reading & Source Based Writing, Niall Nance-Carroll

Fall 2024

No abstract provided.


The Next Public Health Frontier With Indoor Air Quality, Lynette B. Martins Jan 2025

The Next Public Health Frontier With Indoor Air Quality, Lynette B. Martins

Tulsa Law Review

No abstract provided.


Eng 1000-001 College Composition Studio, Ashley Flach Jan 2025

Eng 1000-001 College Composition Studio, Ashley Flach

Spring 2025

No abstract provided.


Eng 1001g-002 College Composition I, Glen Davis Jan 2025

Eng 1001g-002 College Composition I, Glen Davis

Spring 2025

No abstract provided.


Eng 1002g-004 College Composition Ii, Rashelle Spear Jan 2025

Eng 1002g-004 College Composition Ii, Rashelle Spear

Spring 2025

No abstract provided.


Eng 1001g-600 College Composition I, Ashley Flach Jan 2025

Eng 1001g-600 College Composition I, Ashley Flach

Spring 2025

No abstract provided.


Eng 1002g-600 College Composition Ii, Ashley Flach Jan 2025

Eng 1002g-600 College Composition Ii, Ashley Flach

Spring 2025

No abstract provided.


Eng 2901-002 Structure Of English, Angela Vietto Jan 2025

Eng 2901-002 Structure Of English, Angela Vietto

Spring 2025

No abstract provided.


Eng 3005-001 Technical Communication, Rashelle Spear Jan 2025

Eng 3005-001 Technical Communication, Rashelle Spear

Spring 2025

No abstract provided.