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2025

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Effects Of Whole Quinoa Flour Addition On Biscuit Quality And Glycemic Index, Wang Ying, Zhang Xinyi, Yu Bo, Li Yunjie, Tang Shangwen, Wu Jinju Jul 2025

Effects Of Whole Quinoa Flour Addition On Biscuit Quality And Glycemic Index, Wang Ying, Zhang Xinyi, Yu Bo, Li Yunjie, Tang Shangwen, Wu Jinju

Food and Machinery

[Objective] To explore the effects of whole quinoa flour addition on the quality and in vitro digestion characteristics of biscuits.[Methods] Whole quinoa flour,at varying proportions (0%,10%,20%,30%,40%,and 50%),is added to wheat flour to investigate the effects of whole quinoa flour addition on the quality and in vitro digestion characteristics of biscuits.[Results]] Compared with the control group without whole quinoa flour,the groups with whole quinoa flour addition show gradually increased moisture content of quinoa biscuits as well as their hardness gradually decreasing and toughness first increasing and then decreasing as the addition of whole quinoa flour increases.When the addition of whole quinoa …


Extrusion Process Optimization Of Sea Red Rice And Its Physicochemical Properties , Digestion Characteristics , And Nutritional Components, Sun Wufei, Wang Zhuo, Zhong Saiyi, Zou Wentao, Hu Jiakang Jul 2025

Extrusion Process Optimization Of Sea Red Rice And Its Physicochemical Properties , Digestion Characteristics , And Nutritional Components, Sun Wufei, Wang Zhuo, Zhong Saiyi, Zou Wentao, Hu Jiakang

Food and Machinery

[Objective] To investigate the effects of extrusion technology on the physicochemical properties,digestion characteristics,and nutritional components of sea red rice.[Methods] The extrusion process parameters for sea red rice are optimized by response surface methodology.The effects of the extrusion treatment on the physicochemical properties of the sea red rice flour are explored by water solubility index (WSI ),gelatinization degree,starch digestion properties (including rapidly digestible starch,slowly digestible starch,and resistant starch ),and the anti -nutritional factor content (phytic acid ).The microstructure,starch crystal form,and crystallinity are 钟赛意(1979—),男,广东海洋大学教授,博士。E-mail:zsylxc@ 126.com引用格式:孙武飞,汪卓,钟赛意,等.海红米挤压工艺优化及理化性质、消化与营养特性研究 [J].食品与机械,2025,41(6):164-172.C itation:SUN Wufei,WANG Zhuo,ZHONG Saiyi,et al.Extrusion process optimization of sea red rice and its physicochemical properties,digestion characteristics,and …


Preparation And Structural Analysis Of Antioxidant Peptides From Tilapia Skin By Microwave-Assisted Enzymatic Hydrolysis, Mi Chunxiao, Zhou Hui, Hu Xingyuan, Zhu Wanting, Wu Long Jul 2025

Preparation And Structural Analysis Of Antioxidant Peptides From Tilapia Skin By Microwave-Assisted Enzymatic Hydrolysis, Mi Chunxiao, Zhou Hui, Hu Xingyuan, Zhu Wanting, Wu Long

Food and Machinery

[Objective] To prepare antioxidant peptides from tilapia skin by microwave -assisted enzymatic hydrolysis and conduct structural analysis.[Methods] The processing conditions for preparing antioxidant peptides by microwave pretreatment -assisted alkaline protease hydrolysis are optimized through single -factor and response surface experiments,and the effects of microwave treatment on the structure of fish skin,the relative molecular weight,amino acid composition,and antioxidant activity of antioxidant peptides are analyzed.[Results]] The optimal processing conditions for preparing antioxidant peptides by microwave -assisted enzymatic hydrolysis are as follows:microwave power of 441.50 W,microwave temperature of 61.00 ℃,microwave time of 20 min,hydrolysis time of 6.21 h,enzyme dosage of 2.20%,and solid -to-liquid …


Optimization Of Extraction Process And Property Analysis Of Spirulina Protein Isolate By Alkaline Dissolution And Acid Precipitation, Zhao Qiaoli, Gao Yongqin, Tan Jiedan, Huo Xinyue, Wang Zhuo, Zhong Saiyi Jul 2025

Optimization Of Extraction Process And Property Analysis Of Spirulina Protein Isolate By Alkaline Dissolution And Acid Precipitation, Zhao Qiaoli, Gao Yongqin, Tan Jiedan, Huo Xinyue, Wang Zhuo, Zhong Saiyi

Food and Machinery

[Objective] To optimize the extraction process of spirulina protein isolate and analyze its physicochemical and functional properties.[Methods] The extraction process was optimized using single -factor test and orthogonal test,with the extraction yield of spirulina protein isolate as the evaluation index.Comprehensive comparisons and analyses were conducted on the physicochemical properties,structural characteristics,and functional properties of spirulina protein isolate.[Results]] The optimal extraction conditions for spirulina protein isolate using alkaline dissolution and acid precipitation were as follows:solid -liquid ratio of 1∶20 (g/mL ),extraction time of 1 h,pH value of 8.0,and extraction temperature of 40 ℃.Under these conditions,the yield of spirulina protein isolate reached 280.36 …


Preparation And Bioactivity Of Biochanin A Metal Complexes, Wang Youdi, Luo Yingming, Guo Junxiang, Chen Jie, Yan Bin, Xu Juanjuan Jul 2025

Preparation And Bioactivity Of Biochanin A Metal Complexes, Wang Youdi, Luo Yingming, Guo Junxiang, Chen Jie, Yan Bin, Xu Juanjuan

Food and Machinery

[Objective] To prepare metal complexes of biochanin A (BA) and explore their biological activities.[Methods] Biochanin A was used as the ligand to design and synthesize biochanin A -copper (BA-Cu),biochanin A -zinc (BA-Zn),and biochanin A -chromium (BA-Cr) metal complexes.The structures of the complexes were characterized using methods such as ultraviolet spectroscopy and infrared spectroscopy.The antioxidant activities of the three biochanin A metal complexes were evaluated using the phosphomolybdate complex method,and their anticancer activities were assessed using the CCK -8 assay.[Results]] The experiments successfully prepared the three biochanin A metal complexes,i.e.,BA-Cu,BA-Zn,and BA -Cr.All three metal complexes exhibited good antioxidant activities,which were higher …


Optimization Of Fermentation Process Of Anoectochilus Roxburghii (Wall . ) Lindl By Lactobacillus Plantarum And Antioxidant Activity Of Fermentation Broth, Wang Qiongjun, Lin Zeyan, Lin Yanyan, Zhang Qian, Lin Yihua, Fu Dahua Jul 2025

Optimization Of Fermentation Process Of Anoectochilus Roxburghii (Wall . ) Lindl By Lactobacillus Plantarum And Antioxidant Activity Of Fermentation Broth, Wang Qiongjun, Lin Zeyan, Lin Yanyan, Zhang Qian, Lin Yihua, Fu Dahua

Food and Machinery

[Objective] To analyze the fermentation process and antioxidant activity of Anoectochilus roxburghii (Wall.) Lindl using Lactobacillus plantarum 191046.[Methods] A.roxburghii was used as the raw material,and L.plantarum 191046 was used as the fermentation strain.The polysaccharide content of A.roxburghii was used as the evaluation index.The fermentation process was optimized by single -factor experiments combined with response surface methodology,and its in vitro antioxidant activity was assessed.[Results]] The optimal fermentation conditions for A.roxburghii were as follows:L.plantarum inoculum of 4.50 g/L,fermentation time of 17 h,and fermentation temperature of 36 ℃.Under these conditions,the polysaccharide content of the fermentation liquid was (24.84±0.05) mg/mL.The total antioxidant capacity was …


Effect Of White Kidney Bean Extract On The Quality Of Set Yogurt, Wang Zihan, Li Yuexing, Cai Yongjian, Wang Jianhui Jul 2025

Effect Of White Kidney Bean Extract On The Quality Of Set Yogurt, Wang Zihan, Li Yuexing, Cai Yongjian, Wang Jianhui

Food and Machinery

[Objective] To investigate the effect of white kidney bean extract (WBE ) on the physicochemical properties and flavor of set yogurt.[Methods] The pH value,acidity,water -holding capacity,texture properties,and volatile flavor characteristics of set yogurt are analyzed using a pH meter,titrimetric method,centrifugation and weighing method,texture analyzer,and electronic nose,respectively.[Results]] WBE significantly promotes yogurt fermentation (P<0.05),with water -holding capacity,hardness,and content of benzene volatile flavor compounds all superior to the control group.Adding 0.9% WBE increases the water -holding capacity of yogurt by 13.11%,and the hardness and viscosity by 9.46% and 13.19%,respectively.Besides,the addition of WBE reduces the content of hydrides and nitrogen oxides in volatile flavor compounds of yogurt,while increasing the content of long -chain alkanes in volatile flavor compounds.According to correlation heat maps,the addition of 0.9% WBE is positively correlated with the water -holding capacity,content of long -chain alkanes,hardness,viscosity,absolute value of adhesiveness,and absolute value of cohesiveness of yogurt,indicating that it can synergistically optimize the texture and flavor of yogurt,and enhance the overall quality.[Conclusion] Adding 0.9% WBE helps yogurt fermentation and significantly improves the texture and flavor characteristics of set yogurt.


Effect Of Oil Extraction Process On The Flavor Of Idesia Polycarpa Oil, Hu Bokai, Shui Huixia, Geng Yangyang, Zhang Dongya, Yang Xiaohong Jul 2025

Effect Of Oil Extraction Process On The Flavor Of Idesia Polycarpa Oil, Hu Bokai, Shui Huixia, Geng Yangyang, Zhang Dongya, Yang Xiaohong

Food and Machinery

[Objective] This study aimed to investigate the influence of different oil extraction methods on the volatile flavor compounds of Idesia polycarpa oil.[Methods] The volatile flavor compounds of Idesia polycarpa oil extracted by screw pressing,hydraulic pressing,water extraction,and petroleum ether extraction methods were analyzed using headspace -solid phase microextraction -gas chromatography -mass spectrometry (HS-SPME -GC-MS).The main volatile aroma compounds were determined based on their relative odor activity values (ROAV ).[Results]] A total of 8 classes and 114 volatile flavor compounds were detected in Idesia polycarpa oil,with 12 common compounds comprising 9.92% to 24.21% of the total content,and specific compounds accounting for 7.5% …


Research Progress In Xylo-Oligosaccharides By Hydrothermal Preparation And Its Separation And Purification, Shen Xiaoyan, Chen Liang, Qi Hui, Liu An, Wei Dongning, Deng Ming, Wang Keqin, Wu Xiaofen Jul 2025

Research Progress In Xylo-Oligosaccharides By Hydrothermal Preparation And Its Separation And Purification, Shen Xiaoyan, Chen Liang, Qi Hui, Liu An, Wei Dongning, Deng Ming, Wang Keqin, Wu Xiaofen

Food and Machinery

Xylo -oligosaccharides are functional oligosaccharides with prebiotic activity derived from lignocellulosic biomass.They possess excellent physicochemical properties and physiological functions,such as regulating the intestinal microecological balance and preventing cardiovascular diseases,and have been widely applied in the food,pharmaceutical,and other industries.This paper mainly reviews the latest progress in the hydrothermal preparation of xylo -oligosaccharides and subsequent purification methods,such as solvent extraction,adsorption,membrane separation,and chromatographic separation,and provides an outlook on their future development.


Research Progress Of 3d Printing Technology In Health Food Processing, Wang Guoxia, Li Chunge, Wu Si, Li Mengdan, Song Zongyu Jul 2025

Research Progress Of 3d Printing Technology In Health Food Processing, Wang Guoxia, Li Chunge, Wu Si, Li Mengdan, Song Zongyu

Food and Machinery

As a new food processing technology controlled by digitization,three -dimensional printing technology is featured with diverse shapes,material saving,and balanced nutrition.In modern food processing,more and more consumers have begun to pay attention to healthy food,which can not only alleviate the food shortage but also supplement certain nutrition.Therefore,the combination of 3D printing technology and these substances will become an important direction for the future development of modern food.Based on the discussion over equipment types commonly used in the process of 3D food printing,the current situation of the processing and application of 3D printing technology in health food is summarized.Approaches to improve the …


Testosterone Deficiency And Treatments: Common Misconceptions And Practical Guidance For Patient Care, Mohit Khera, James M Hotaling, Martin Miner Jul 2025

Testosterone Deficiency And Treatments: Common Misconceptions And Practical Guidance For Patient Care, Mohit Khera, James M Hotaling, Martin Miner

Faculty, Staff and Students Publications

Introduction: Misconceptions about testosterone therapy are prevalent and there is an unmet need for a review of current literature that can be leveraged by physicians to deliver safe and effective care for men with hypogonadism.

Objectives: This review aims to address common misconceptions about testosterone therapy using current literature and synthesize practical guidance for clinicians with patients who are starting testosterone therapy.

Methods: A literature search of PubMed, Embase, CINAHL was carried out to identify associations between testosterone therapy and prostate cancer, cardiovascular risk, and hepatic toxicity; definitions of hypogonadism; and practical guidance for clinician with patients starting testosterone therapy. …


Satellites For Development, Broadcasting And Information Jul 2025

Satellites For Development, Broadcasting And Information

Communication Research Trends

The symbol of the 'global village' is the communications satellite. For over twenty years, ever since the. USSR launched Sputnik in 1957, the USA and the USSR in particular, and other countries too, have been devoting ever more financial and human resources to the building of ever more elaborate satellite systems; Today a host of communication satellites are positioned in geostationary orbit 22,282 miles (35,860 kilometres) above the equator. The globe is encircled by a communications network that links the most distant parts of the earth in a matter of seconds.

A communications satellite system consists of three parts. The …


First Case Of Sexual Cannibalism In Leiurus Abdullahbayrami Yağmur, Koç & Kunt, 2009 (Scorpiones: Buthidae) From Lebanon, Rami Khashab Jul 2025

First Case Of Sexual Cannibalism In Leiurus Abdullahbayrami Yağmur, Koç & Kunt, 2009 (Scorpiones: Buthidae) From Lebanon, Rami Khashab

Euscorpius

This study presents the first report of sexual cannibalism in the medically significant scorpion Leiurus abdullahbayrami Yağmur, Koç & Kunt, 2009, that was recorded during a herpetological field trip to the semi-desert area in northern Lebanon. It broadens the understanding of sexual cannibalism in scorpions and adds a new prey item to the dietary spectrum of the scorpion.


Exploring The Impact Of A Middle Level School Therapy Dog On Students And Staff And Connections To Best Practices In Middle School Education, Brandye Nobiling, Sherry Maykrantz, Tara Downes, Joshua Nobiling Jul 2025

Exploring The Impact Of A Middle Level School Therapy Dog On Students And Staff And Connections To Best Practices In Middle School Education, Brandye Nobiling, Sherry Maykrantz, Tara Downes, Joshua Nobiling

Current Issues in Middle Level Education

The presence of therapy dogs in schools has increased due to the growing body of research showing positive effects of assisted-animal interaction. But there is little published research on how an innovation such as a therapy dog connects to best practices in middle level education. The goal of the research was to use the Diffusion of Innovation (DOI) theory to connect the implementation of a therapy dog to the Association for Middle Level Education’s (AMLE) essential attributes and characteristics as well as components of the Centers for Disease Control and Prevention’s Whole School, Whole Community, Whole Child (WSCC) model. Focus …


Interprofessional Collaboration To Address Social Isolation And Facilitate Intergenerational Service Learning Within Graduate Education, Angela Lavery, Erin Knight, Stephanie Cole, Stacie Metz Jul 2025

Interprofessional Collaboration To Address Social Isolation And Facilitate Intergenerational Service Learning Within Graduate Education, Angela Lavery, Erin Knight, Stephanie Cole, Stacie Metz

Journal of Community Engagement and Higher Education

This article presents an interdisciplinary collaboration to address the needs of older adults at risk of social isolation exacerbated by the COVID-19 pandemic. An intergenerational service-learning program developed by the Pennsylvania Department of Aging was offered to several universities across the state of Pennsylvania. The authors share their experience and lessons learned from pairing older adults with graduate students studying in the fields of Gerontology, Public Health, and Social Work.


Environmental Exposures Increase Health Risks In Childhood Cancer Survivors., Omar Shakeel, Nicole Wood, Hannah M. Thompson, Michael E. Scheurer, Mark D. Miller Jul 2025

Environmental Exposures Increase Health Risks In Childhood Cancer Survivors., Omar Shakeel, Nicole Wood, Hannah M. Thompson, Michael E. Scheurer, Mark D. Miller

Manuscripts, Articles, Book Chapters and Other Papers

Childhood cancer survivors (CCSs) are at increased risk for chronic health issues due to late effects of cancer and its treatment. We address the impact of environmental exposures, such as air pollution, tobacco smoke, extreme weather events, and pesticides, on the health and survival of CCSs. These environmental hazards have been associated with worsening health outcomes and decreased survival among CCSs on a global scale. We also highlight that providers at a major pediatric cancer center in the United States have limited knowledge and practical skills about environmental risk factors and how to reduce exposures. Our survey results show that …


Community-Based, Culturally Relevant Stem: Engaging Rural And Indigenous Students Through Partnerships, Institutional Flexibility, And One Health, Ellen Chenoweth, Paul Cotter, Janice Straley, Kari Lanphier Jul 2025

Community-Based, Culturally Relevant Stem: Engaging Rural And Indigenous Students Through Partnerships, Institutional Flexibility, And One Health, Ellen Chenoweth, Paul Cotter, Janice Straley, Kari Lanphier

Faculty, Staff, and Students

Rural and Indigenous students face many barriers to persistence in biomedical and STEM trajectories including poor access to science experiences, a dearth of relatable educational resources, and educational structures misaligned with rural and Indigenous student and community needs. Rural Alaska Students in One Health Research (RASOR) is designed to provide a positive first college experience for rural and Indigenous students. Key innovations include 1) a partnership between the University of Alaska and tribal governments to allow for culturally relevant, locallymentored research experiences and 2) a customizable program structure. We also surveyed adults in the region regarding attitudes about science, its …


Stream Fish Assemblage Dynamics And Barriers To Aquatic Connectivity In The Ichawaynochaway Creek Watershed, Georgia, Usa, Jake R. Duhé Jul 2025

Stream Fish Assemblage Dynamics And Barriers To Aquatic Connectivity In The Ichawaynochaway Creek Watershed, Georgia, Usa, Jake R. Duhé

LSU Master's Theses

Stream fishes in the southeastern United States are adapted to hydrological disturbances such as droughts. However, this region is projected to experience increasingly frequent and severe disturbances that will elevate water demands given increasing agricultural and urban development. Further, road-stream crossings (RSCs) are abundant features in these streams that can exacerbate drought-mediated stream fragmentation and impede movements by many aquatic organisms, including fishes, when poorly constructed. These compounding effects may adversely affect the diversity and abundances of resident stream fishes, but their interactions remain poorly understood, warranting rigorous testing of how droughts and RSCs influence stream fish dynamics. I assessed …


Alma Link Resolver Title & Issn Report (Top 500) 2024-2025, Andrée J. Rathemacher Jul 2025

Alma Link Resolver Title & Issn Report (Top 500) 2024-2025, Andrée J. Rathemacher

Technical Services Reports and Statistics

Statistics for 2024-2025 on the total number of OpenURL requests by journal title and ISSN made to the Ex Libris Alma link resolver for items held by the University of Rhode Island Libraries. Includes only the top 500 journals.

Information provided includes journal Title, ISSN, EISSN, Number of Requests, Number of Clicked Requests, % Clicks from Requests.


July 2025, Office Of Sustainability Jul 2025

July 2025, Office Of Sustainability

Office of Sustainability Newsletter

No abstract provided.


Predictive Indicators For Graduation Upon Acceptance Into A Naacls-Approved Medical Laboratory Science Program, Warren Hovis Jul 2025

Predictive Indicators For Graduation Upon Acceptance Into A Naacls-Approved Medical Laboratory Science Program, Warren Hovis

LSU Doctoral Dissertations

The primary purpose of this study was to determine the influence of selected academic and personal demographic characteristics on student success at a NAACLS-accredited medical laboratory science program in the southern portion of the United States.

Both academic and demographic categories were selected on students who entered the medical laboratory science program from 2014 to 2019 (pre-COVID). The sanitized, archived data set was provided by the MLS department and the registrar and student affairs office at the participating school. The extant data set contained academic and demographic variables, collected over a five-year period, of initially over 170 accepted MLS students. …


Artificial Intelligence For Detecting Non-Alcoholic Steatohepatitis (Nash), Muhammad Wildan Gifari, Yogi Ramadhani, Dhadhang Wahyu Kurniawan Jul 2025

Artificial Intelligence For Detecting Non-Alcoholic Steatohepatitis (Nash), Muhammad Wildan Gifari, Yogi Ramadhani, Dhadhang Wahyu Kurniawan

Pharmaceutical Sciences and Research

Non-alcoholic steatohepatitis (NASH), an inflammatory disease of the liver, has recently raised concern among healthcare professionals worldwide due to its asymptomatic features, making early diagnosis challenging. If left unnoticed, NASH often progresses to lethal diseases such as liver fibrosis or hepatocellular carcinoma. Recent developments in the field of artificial intelligence (AI) might facilitate the early diagnosis of NASH in a more efficient manner, forming a promising strategy to diagnose patients. In simple terms, AI is any machine that is capable of human-level intelligence, including visual perception, speech recognition, or decision making. A subclass of AI, which particularly deals with knowledge-based …


Impact Of Fructose-Enhanced Solid And Soft Drink Diets On Metabolism, Physiology, And Gut Microbiome In Pregnant Rats, Xiaoyuan Han, Linda D. Shortliffe, Neeraja Kambham Jul 2025

Impact Of Fructose-Enhanced Solid And Soft Drink Diets On Metabolism, Physiology, And Gut Microbiome In Pregnant Rats, Xiaoyuan Han, Linda D. Shortliffe, Neeraja Kambham

Pacific Faculty Work

Introduction: High fructose consumption is linked to hypertension and metabolic disorders. We hypothesize fructose (solid and/or liquid) may further influence dietary patterns. To investigate potential effects, we compared eating behaviors, physiological and metabolic measures, and gut microbiome in pregnant rats fed solid or liquid fructose-enhanced (soft drink) diets to those fed standard chow. Methods: Pregnant rats were assigned to three dietary groups: (1) standard chow and water (CW), (2) standard chow and decarbonated soft drink (CS, decarbonated Sprite with 5.89% fructose w/v), and (3) 60% fructose chow and water (FW). Body weight, blood pressure, food and liquid intake, fasting blood …


Evaluating Nutrition, Exercise, And Education, On Mental Health And Quality Of Life In Menopause, Jill R. Stone Jul 2025

Evaluating Nutrition, Exercise, And Education, On Mental Health And Quality Of Life In Menopause, Jill R. Stone

Walden Dissertations and Doctoral Studies

Physical inactivity, poor nutrition, and a lack of understanding of menopause adversely affect mental health and quality of life in women entering menopause. Metabolic changes during this period can lead to an increase in visceral fat, loss of muscle mass, depression, and anxiety. These metabolic changes are linked to a higher risk for cardiovascular disease, type two diabetes, and metabolic syndrome. This cross-sectional quantitative study, guided by the health belief model, explored the contribution of adopting specific nutrition strategies, exercise, and education in women during menopause transition to help manage mental health (as measured by depression and tension), and quality …


Medical Biotechnology Symposium Sultan Qaboos University, Muscat, Oman 5th And 6th February 2024 Gene Hunting In Breast Tumours And Cells To Reveal Chemotherapy Resistance As Predictive Markers Of Response, Sultan Qaboos University Jul 2025

Medical Biotechnology Symposium Sultan Qaboos University, Muscat, Oman 5th And 6th February 2024 Gene Hunting In Breast Tumours And Cells To Reveal Chemotherapy Resistance As Predictive Markers Of Response, Sultan Qaboos University

Sultan Qaboos University Medical Journal

No abstract provided.


Protective Role Of Dietary Short-Chain Fatty Acid Propionate Against Autoimmune Responses And Pathology Of Systemic Lupus Erythematosus In Mrl-Lpr Mice, Hui Wang, Yuejin Liang, Paul J Boor, Kamil Khanipov, Yuanyi Zhang, Xiaoying Yu, Chandra Shekar R Ambati, Nagireddy Putluri, M Firoze Khan Jul 2025

Protective Role Of Dietary Short-Chain Fatty Acid Propionate Against Autoimmune Responses And Pathology Of Systemic Lupus Erythematosus In Mrl-Lpr Mice, Hui Wang, Yuejin Liang, Paul J Boor, Kamil Khanipov, Yuanyi Zhang, Xiaoying Yu, Chandra Shekar R Ambati, Nagireddy Putluri, M Firoze Khan

Faculty, Staff and Students Publications

Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs, including the skin and kidneys. The etiology of SLE remains unclear but involves hormonal, environmental, and genetic factors. Environmental factors, such as diet and microbiota-derived metabolites, among which short-chain fatty acids (SCFAs) are major players, can influence autoimmune disease pathogenesis.

Objectives: This study investigates the involvement of SCFAs in the pathogenesis of SLE and further investigates the effect of propionate (PA) supplementation on SLE disease outcome in MRL-lpr mice.

Methods: Cecal SCFAs from mouse models with varying degrees of SLE disease activities (C57BL/6, MRL+/+, and MRL-lpr) …


Environmental Exposures Increase Health Risks In Childhood Cancer Survivors, Omar Shakeel, Nicole M Wood, Hannah M Thompson, Michael E Scheurer, Mark D Miller Jul 2025

Environmental Exposures Increase Health Risks In Childhood Cancer Survivors, Omar Shakeel, Nicole M Wood, Hannah M Thompson, Michael E Scheurer, Mark D Miller

Faculty, Staff and Students Publications

Childhood cancer survivors (CCSs) are at increased risk for chronic health issues due to late effects of cancer and its treatment. We address the impact of environmental exposures, such as air pollution, tobacco smoke, extreme weather events, and pesticides, on the health and survival of CCSs. These environmental hazards have been associated with worsening health outcomes and decreased survival among CCSs on a global scale. We also highlight that providers at a major pediatric cancer center in the United States have limited knowledge and practical skills about environmental risk factors and how to reduce exposures. Our survey results show that …


Innovating For Improvement — Improving Pressure Damage Prevention And Treatment In The Community Using Continuous Pressure Monitoring, Bridie Kent, Nicci Aylward-Wotton, Peter R. Worsley Jul 2025

Innovating For Improvement — Improving Pressure Damage Prevention And Treatment In The Community Using Continuous Pressure Monitoring, Bridie Kent, Nicci Aylward-Wotton, Peter R. Worsley

School of Nursing and Midwifery

Each year, approximately half a million people in the UK develop pressure ulcers (PUs), with most occurring in the community among individuals with underlying comorbidities, frailty, mobility issues and a dependence on carers. Pressure relief is essential for healing, however, some patients find pressure-relieving equipment uncomfortable, hot and noisy, thus refusing to use it and are, therefore, often labelled as non-concordant. This service improvement project evaluated the ForeSite PT® pressure monitor to identify PU risk, support healing and influence patient and carer decision making, assessing its useability, alongside patient and carer education. The technology consisted of a mattress- and chair-sized …


Cat: A Conditional Association Test For Microbiome Data Using A Permutation Approach, Yushu Shi, Liangliang Zhang, Kim-Anh Do, Robert R Jenq, Christine B Peterson Jul 2025

Cat: A Conditional Association Test For Microbiome Data Using A Permutation Approach, Yushu Shi, Liangliang Zhang, Kim-Anh Do, Robert R Jenq, Christine B Peterson

Faculty, Staff and Student Publications

In microbiome analysis, researchers often seek to identify taxonomic features associated with an outcome of interest. However, microbiome features are intercorrelated and linked by phylogenetic relationships, making it challenging to assess the association between an individual feature and an outcome. This paper proposes a novel conditional association test, CAT, that can account for other features and phylogenetic relatedness when testing the association between a feature and an outcome. CAT adopts a permutation approach, measuring the importance of a feature in predicting the outcome by permuting operational taxonomic unit/amplicon sequence variant counts belonging to that feature from the data and quantifying …


A Sensory Investment Syndrome Hypothesis: Personality And Predictability Are Linked To Sensory Capacity In The Hermit Crab Pagurus Bernhardus, Ari Drummond, Summer Nash, Tianna Holloway, Alexander Wilson, Lucy Turner, Mark Briffa Jul 2025

A Sensory Investment Syndrome Hypothesis: Personality And Predictability Are Linked To Sensory Capacity In The Hermit Crab Pagurus Bernhardus, Ari Drummond, Summer Nash, Tianna Holloway, Alexander Wilson, Lucy Turner, Mark Briffa

School of Biological and Marine Sciences

Correlated phenotypic traits (i.e., syndromes) may manifest as associations between different behavioural types or between behavioural and non-behavioural phenotypes. While syndromes research is extensive, correlations involving behavioural type and sensory morphology have yet to be investigated. Sensation is essential in decision-making and should be correlated with behavioural phenotypes involved in risk response, including boldness. We investigated correlations between boldness and sensory capacity in Pagurus bernhardus hermit crabs, taking repeat measures of startle response durations to assess hermit crab personality and predictability. The correlation between startle response and the sensillar density (i.e., number of sensilla per unit surface area) of both …