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2025

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Hallucinations, Children's Mercy Kansas City Nov 2025

Hallucinations, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.


Cultural Humility In Patient Education: Development Of A Nutrition-Related Simulation For Nursing Students, Theresa G. Schnable, Sylvia Peña, Juanita T. Garcia, Marilyn Frenn Nov 2025

Cultural Humility In Patient Education: Development Of A Nutrition-Related Simulation For Nursing Students, Theresa G. Schnable, Sylvia Peña, Juanita T. Garcia, Marilyn Frenn

College of Nursing Faculty Research and Publications

Introduction:

The Latinx community is disproportionately impacted by social and structural inequities such as food insecurity and culturally and linguistically appropriate resources. To address a gap in culturally appropriate nutrition education with Latinx individuals among baccalaureate nursing students, a simulation learning experience (SLE) was developed.

Methodology:

The SLE was designed using best practice standards by faculty experts and reviewed by consultants. After the SLE, students and faculty provided feedback regarding simulation design and implementation.

Results:

Participants reported improved knowledge and confidence when providing culturally appropriate nutrition education and valued working with an interpreter.

Discussion:

This innovative strategy using simulation offers …


The Anchor: November 2025, Hope College Nov 2025

The Anchor: November 2025, Hope College

The Anchor: 2025

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.


A Tri-Stage Interval-Neutrosophic Linguistic Decision Framework For Designing Intangible Cultural Heritage Food Education Programs In Primary Schools, Donghao Jin Nov 2025

A Tri-Stage Interval-Neutrosophic Linguistic Decision Framework For Designing Intangible Cultural Heritage Food Education Programs In Primary Schools, Donghao Jin

Neutrosophic Sets and Systems

No abstract provided.


Mortality Among Transgender Persons: A Taiwan Matched-Population And Sibling-Comparison Cohort Study, Chih-Wei Hsu, Yang-Chieh Brian Chen, Liang-Jen Wang, Mu-Hong Chen, Yao-Hsu Yang, Chih-Sung Liang, Po-Yen Chen, Edward Chia-Cheng Lai Nov 2025

Mortality Among Transgender Persons: A Taiwan Matched-Population And Sibling-Comparison Cohort Study, Chih-Wei Hsu, Yang-Chieh Brian Chen, Liang-Jen Wang, Mu-Hong Chen, Yao-Hsu Yang, Chih-Sung Liang, Po-Yen Chen, Edward Chia-Cheng Lai

Children’s Nutrition Research Center Staff Publications

Background: Transgender persons have been reported to experience excess mortality, but evidence is dominated by Western cohorts and seldom addresses familial confounding.

Methods: We conducted a nationwide, retrospective cohort study using two prespecified comparison designs: matched population controls (1:4, matched on legal sex and birth date) and within-family cisgender sibling comparisons. Transgender persons were identified by ≥2 psychiatrist-recorded gender identity disorder diagnoses during 2001-2021; cohort entry required age ≥6 years. Participants were followed until death or December 31, 2022. We compared all-cause, external-cause (suicide and accidents), and internal-cause mortality using Cox regression adjusted for sociodemographics and medical comorbidity.

Findings: Among …


Concerns Regarding The Standard Deviation Of Individual Responses For Assessing Treatment Response Heterogeneity, Aaron R Caldwell, David B Allison, Andrew W Brown, Gary L Gadbury, Thirupathi Reddy Mokalla, R Drew Sayer, Andrew D Vigotsky Nov 2025

Concerns Regarding The Standard Deviation Of Individual Responses For Assessing Treatment Response Heterogeneity, Aaron R Caldwell, David B Allison, Andrew W Brown, Gary L Gadbury, Thirupathi Reddy Mokalla, R Drew Sayer, Andrew D Vigotsky

Children’s Nutrition Research Center Staff Publications

The estimation of treatment response heterogeneity (TRH) is increasingly important as medicine moves toward personalized approaches. While various statistical methods have been proposed to quantify TRH in parallel-group trials, the standard deviation of individual responses (SDIR) has gained prominence within physiological research. This method is intended to quantify individual response variation by comparing standard deviations of change scores between intervention and control groups. We acknowledge that SDIR represents an improvement over many other flawed approaches that often involve responder counting. However, SDIR has critical limitations: 1) it cannot overcome the fundamental problem of causal inference because the correlation between potential …


Attitudes Of New York State Pediatric Dentists Toward Treating Hasidic Patients, Gideon Turk Dmd, Michelle Goldstein Dmd Nov 2025

Attitudes Of New York State Pediatric Dentists Toward Treating Hasidic Patients, Gideon Turk Dmd, Michelle Goldstein Dmd

The New York State Dental Journal

Purpose: This survey investigated variations in practices among pediatric dentists and dental residents in New York State concerning the treatment of Hasidic, Haredi or Ultra-Orthodox Jewish (HHUOJ) patients.

Methods and Results: The 16-question survey was distributed to 641 AAPD pediatric dentists and residents via email. Results were analyzed across six variables using the Mann-Whitney U Test. Statistically significant differences were observed in the responses to 14 of 16 questions.

Conclusion: The study revealed statistically significant variations in various aspects related to the treatment of HHUOJ patients, suggesting the need for further education among providers in New York State.


Development And Characterization Of Sustainable Aluminum Metal Matrix Composites With Date Palm Agro-Residues As Reinforcement, Ansar Kareem Nov 2025

Development And Characterization Of Sustainable Aluminum Metal Matrix Composites With Date Palm Agro-Residues As Reinforcement, Ansar Kareem

Dissertations

Aluminum Matrix Composites (AMCs) are extensively used in various industrial applications owing to their exceptional mechanical, material, and tribological properties. This led to the development of AMCs with every possible aluminum alloy as matrix, incorporated with various reinforcement materials to achieve desired material properties. There has been an increasing trend in the utilization of agricultural and industrial waste products as reinforcement material in AMCs. Date palm trees produce huge quantity of agricultural waste in different forms. Usually, these wastes are burned or disposed of in landfills which cause environmental pollution. Date palm agro-wastes can be incinerated to produce date palm …


Structural-Level Stigma Within Emergency Food Assistance Programs: Perspectives From Delaware And Pennsylvania, Mckenna M Halverson, Evyn Y Appel, Valerie A Earnshaw, Raquelle Powell, Grace Sands, Nithila Chrisostam, Shreela V Sharma, Allison Karpyn Nov 2025

Structural-Level Stigma Within Emergency Food Assistance Programs: Perspectives From Delaware And Pennsylvania, Mckenna M Halverson, Evyn Y Appel, Valerie A Earnshaw, Raquelle Powell, Grace Sands, Nithila Chrisostam, Shreela V Sharma, Allison Karpyn

Faculty, Staff and Student Publications

To characterize the ways in which structural stigma manifests within emergency food program settings.

Methods : We conducted 30-minute semi-structured interviews with 18 emergency food program clients in Pennsylvania and Delaware between August and December of 2024. The discussion guide included open-ended questions regarding client experiences of structural stigma, with an emphasis on issues of access and quality. Demographic data and household food insecurity (Hunger Vital Sign) were also captured. A hybrid inductive and deductive coding approach was used to analyze the data.

Results : Structural stigma is a persistent issue within emergency food program environments, impacting both participant access …


Mitigating Food Insecurity-Related Stigma: A Review Of Intervention Strategies, Evyn Y Appel, Mckenna M Halverson, Valerie A Earnshaw, Tania Cruz Cordero, Maya Rozin, Raquelle Powell, Grace Sands, Nithila Chrisostam, Sarah E Katz, Shreela V Sharma, Allison Karpyn Nov 2025

Mitigating Food Insecurity-Related Stigma: A Review Of Intervention Strategies, Evyn Y Appel, Mckenna M Halverson, Valerie A Earnshaw, Tania Cruz Cordero, Maya Rozin, Raquelle Powell, Grace Sands, Nithila Chrisostam, Sarah E Katz, Shreela V Sharma, Allison Karpyn

Faculty, Staff and Student Publications

Objective: To characterize intervention strategies addressing food insecurity-related stigma implemented in federal nutrition programs (e.g. SNAP, WIC) and emergency food programs (e.g. food pantries, food cupboards) within high income countries.

Methods: Six databases (PubMed, PsychINFO, Web of Science, CINAHL, Sociological Abstracts, Dissertations and Theses Global) and the Internet were searched through September 2024. Data on study characteristics and stigma intervention characteristics were extracted with a structured template. Descriptive statistics and thematic analysis were used.

Results: The review found 46 intervention strategies across 18 articles. The majority of articles were based in the United States (89.9%) with the remaining portion from …


Ai Recipe Blog Is Evaluated Similarly To A Recipe Blog Created By Nutrition And Dietetic Students, Katie N. Kraus, Stacy L. Bevan, Sarah Moore Smith, Maeci H. Armstrong, Brooke Campbell Jeppesen, Catherine Fish, Heidi J. Wengreen Nov 2025

Ai Recipe Blog Is Evaluated Similarly To A Recipe Blog Created By Nutrition And Dietetic Students, Katie N. Kraus, Stacy L. Bevan, Sarah Moore Smith, Maeci H. Armstrong, Brooke Campbell Jeppesen, Catherine Fish, Heidi J. Wengreen

Nutrition, Dietetics, and Food Sciences Faculty Publications

With the growing use of AI, it is important to know target audiences’ perceptions of its use. A convenience sample of students were invited to take an online survey in which they were randomly assigned to Group 1 (evaluated a student-generated blog; n = 456) or Group 2 (evaluated an AI-generated blog; n = 492). The results of independent t-tests and chi-squared tests indicated no group differences in ratings of ease of recipe preparation, time to prepare the recipe, utilization of common ingredients, and frequency of intended use of the blog. The student-generated blog was rated higher on budget …


Evaluating Interactions Between National And Subnational Governments In The Czech Republic For Physical Activity Policy Development And Implementation, Michael Pratt, Juliana Mejía-Grueso, Eugen Resendiz, Aleš Jakubec, Zdeněk Hamřík, Deborah Salvo, Andrea Ramírez Varela, Josef Mitáš Nov 2025

Evaluating Interactions Between National And Subnational Governments In The Czech Republic For Physical Activity Policy Development And Implementation, Michael Pratt, Juliana Mejía-Grueso, Eugen Resendiz, Aleš Jakubec, Zdeněk Hamřík, Deborah Salvo, Andrea Ramírez Varela, Josef Mitáš

Faculty, Staff and Student Publications

Background: Most countries now have physical activity (PA) policies but translating them into action at national and subnational levels remains poor. To better understand the disconnect, the "Interaction between National and Local Government Levels in Development and Implementation of Physical Activity Policies Tool" (INTEGRATE-PA-Pol) was developed by the Global Observatory for Physical Activity (GoPA!).

Methods: The Czech Republic was chosen as a European pilot site based on existing research capacity and relationships. The INTEGRATE-PA-Pol tool was translated and adapted for use in the country. This questionnaire-based tool has 8 components assessing government levels, political system, and sectors across the 5 …


N Y State Dent J November 2025 Nov 2025

N Y State Dent J November 2025

The New York State Dental Journal

In the November 2025 issue, the reader will find the following feature articles:

  • "Attitudes of New York State Pediatric Dentists Toward Treating Hasidic Patients"
  • "A Qualitative Assessment of the Role of Dental Specialists in U.S. Opioid Epidemic"
  • "Revolutionizing Dental Operatories"
  • "An Update on Non-Cigarette Nicotine-Containing Products and the Periodontal Patient"

This issue includes regular columns with regional news impacting the New York membership including: editorial and legal columns, association activities, component news, continuing education opportunities, and classifieds.


Buy Better: How Food Policy Councils Leverage Procurement To Improve Food Worker Conditions, Frank Sarfo, Laura-Anne Minkoff-Zern, Jonnell A. Robinson Nov 2025

Buy Better: How Food Policy Councils Leverage Procurement To Improve Food Worker Conditions, Frank Sarfo, Laura-Anne Minkoff-Zern, Jonnell A. Robinson

The Lender Center for Social Justice

Food system workers; farm laborers, grocery clerks, restaurant staff, and food processors are the backbone of our everyday meals, yet their voices are largely missing from the councils that shape local food policy. Despite being essential to food security and community health, these workers face low wages, poorworking conditions, and limited protections. Food Policy Councils (FPCs), which aim to advance equity and sustainability in food systems, rarely prioritize labor issues. The study, drawing on national survey data and interviews with over 25 FPC leaders, finds that structural constraints, internal conflicts, limited capacity, and weak connections with labor organizations prevent meaningful …


Theory Of Mind Across Cultures: Psychological Implications, Lewis Hancock, Simon Dein Nov 2025

Theory Of Mind Across Cultures: Psychological Implications, Lewis Hancock, Simon Dein

Online Readings in Psychology and Culture

Theory of Mind (ToM) refers to a set of social and cognitive abilities that we use to infer and understand other people’s mental states. This paper begins by outlining ToM, its component skills, and what research methods have been used to measure it. It then summarises research on how culture and other social factors such as language, parenting, and socio-economic status can impact its development, in particular differences in age of mastery of various aspects of ToM. Mental disorders characterised by deficits in ToM – in particular ASD – are also discussed and used to elucidate its nature and development. …


Screening And Identification Of Antioxidant Peptides From Sea Cucumber Gonad Proteins And Their Activation Of Superoxide Dismutase, Zhiqin Zhang, Jingxuan Wang, Yongke Deng, Yugui Wang, Peipei Dou, Hongbing Fan, Xiangquan Zeng, Xinguang Fan, Lili Zhang, Haimei Liu, Qin Zhao Nov 2025

Screening And Identification Of Antioxidant Peptides From Sea Cucumber Gonad Proteins And Their Activation Of Superoxide Dismutase, Zhiqin Zhang, Jingxuan Wang, Yongke Deng, Yugui Wang, Peipei Dou, Hongbing Fan, Xiangquan Zeng, Xinguang Fan, Lili Zhang, Haimei Liu, Qin Zhao

Animal and Food Sciences Faculty Publications

The gonad is one of the major byproducts of sea cucumber. Four novel antioxidant peptides (NPWGQ, PGHPF, VPYPR and ATGPQGPAGQRGPAGPTGPTGPAG) were isolated and identified from sea cucumber gonad proteins through enzymatic hydrolysis and antioxidant activity-guided fractionation, bioinformatics approaches and in silico screening. These peptides demonstrated great free radical (2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS))-scavenging activity and notable superoxide dismutase (SOD)-activation capacity. Molecular docking and molecular dynamics simulation data suggested that these peptides could form strong binding with SOD through hydrogen bonding, electrostatic interactions, and hydrophobic interactions. Among these peptides, NPWGQ displayed the most potent antioxidant and SOD-activating effects. Through searching …


The Performance, Energy And Nutrient Utilization, And Bone Mineralization Of Broiler Chickens Fed Corn-Soybean Meal-Based Diets With Reduced Metabolizable Energy, Calcium, And Available Phosphorus Supplemented With Exogenous Enzymes, Megan M. Bauer, Tuoying Ao, Jacqueline P. Jacob, Michael J. Ford, Anthony J. Pescatore, Ronan F. Power, Sunday A. Adedokun Nov 2025

The Performance, Energy And Nutrient Utilization, And Bone Mineralization Of Broiler Chickens Fed Corn-Soybean Meal-Based Diets With Reduced Metabolizable Energy, Calcium, And Available Phosphorus Supplemented With Exogenous Enzymes, Megan M. Bauer, Tuoying Ao, Jacqueline P. Jacob, Michael J. Ford, Anthony J. Pescatore, Ronan F. Power, Sunday A. Adedokun

Animal and Food Sciences Faculty Publications

This study evaluated the performance and energy and nutrient utilization of broiler chickens fed corn-soybean meal-based diets supplemented with a naturally fermented enzyme complex containing xylanase and phytase. This was evaluated using 300 one-day-old male Cobb broiler chicks in a randomized complete block design with five dietary treatments replicated 10 times with 6 chicks per replicate. The treatments consisted of a positive control (PC) group containing commercially recommended energy and nutrient levels, a negative control (NC) group with reduced metabolizable energy, calcium, and available phosphorus, and three levels of exogenous enzyme supplementation to the NC diet at 150, 200, 250 …


The 10-Year Status Of Pediatric Gastroenterologists' Perception Of Their Roles In The Management Of Childhood Obesity., Sara Karjoo, Senthilkumar Sankararaman, Fotini Tania Mitsinikos, Marwa Abu El Haija, Sheela Mahendra, Ayesha Baig, Ruba A. Abdelhadi, Ruben E. Quiros-Tejeira, Timothy Sentongo Nov 2025

The 10-Year Status Of Pediatric Gastroenterologists' Perception Of Their Roles In The Management Of Childhood Obesity., Sara Karjoo, Senthilkumar Sankararaman, Fotini Tania Mitsinikos, Marwa Abu El Haija, Sheela Mahendra, Ayesha Baig, Ruba A. Abdelhadi, Ruben E. Quiros-Tejeira, Timothy Sentongo

Manuscripts, Articles, Book Chapters and Other Papers

In 2013, a survey of NASPGHAN members on their involvement in managing pediatric obesity revealed that most pediatric gastroenterologists viewed their roles as primarily supportive, focusing on the management of obesity-related gastrointestinal comorbidities. This 10-year follow-up survey, which targeted pediatric gastroenterology programs and practices, found similar perceptions, along with an increased interest in learning about obesity pharmacotherapy. Additionally, most programs and practices reported limited access to dedicated dietitians, a lack of funding, and a desire for greater institutional support for multidisciplinary programs addressing obesity. Notably, none of the funded programs cited philanthropy as a source of funding. These findings underscore …


Replication-Competent, Tumor-Specific Immuno-Gene Vectors Allow For Exchange Of Transgenes And Lead To Viral Persistence Following Iv Administration, Lee S Rosen, Christian Ottensmeier, Maria Hawkins, Aung Naing, Guru Sonpavde, Brian A Van Tine, Eileen E Parkes, Sean M O'Cathail, Rui-Ru Ji, Matthew Thomas, Andrea Stacey, Maria Stella Sasso, Oliver Rosen Nov 2025

Replication-Competent, Tumor-Specific Immuno-Gene Vectors Allow For Exchange Of Transgenes And Lead To Viral Persistence Following Iv Administration, Lee S Rosen, Christian Ottensmeier, Maria Hawkins, Aung Naing, Guru Sonpavde, Brian A Van Tine, Eileen E Parkes, Sean M O'Cathail, Rui-Ru Ji, Matthew Thomas, Andrea Stacey, Maria Stella Sasso, Oliver Rosen

Faculty, Staff and Student Publications

Introduction: Enadenotucirev (EnAd) and successor transgene-armed Tumor-Specific Immuno-Gene (T-SIGn) vectors are replication-competent, blood-stable viral vectors that traffic to tumor sites following intravenous (IV) administration. Following initial proof of mechanism for this immunotherapy modality, there is a need to identify a safe dosing approach, understand whether transgenes affect tolerability, and determine how to measure exposure and pharmacodynamic effects.

Methods: Safety data from multiple phase 1 trials were aggregated to assess various dosing regimens and toxicities, including those that may be associated with transgene arming. Viral delivery to tumors, peripheral viral persistence, transgene expression, and cytokine responses were also assessed and compared …


Fontan Circulation And Transplantation: Considerations For The Complex Candidate., Drishti Tolani, Sharon Chen, Edo Bedzra, Kurt R. Schumacher, Shahnawaz Amdani Nov 2025

Fontan Circulation And Transplantation: Considerations For The Complex Candidate., Drishti Tolani, Sharon Chen, Edo Bedzra, Kurt R. Schumacher, Shahnawaz Amdani

Manuscripts, Articles, Book Chapters and Other Papers

The Fontan operation has transformed survival for patients with single ventricle congenital heart disease, but the long-term durability of this physiology remains limited. Fontan circulatory failure (FCF) is a progressive, heterogeneous condition associated with multiorgan dysfunction, lymphatic failure, and elevated post-transplant risk when not recognized early. With increasing survival into adulthood, heart transplantation has emerged as the definitive "fourth stage" of palliation. However, referrals for advanced therapies are often delayed, with many patients presenting in advanced stages of decline. This review synthesizes current evidence on the pathophysiology of Fontan failure, outlines consensus indications for transplant evaluation, and highlights pre-transplant strategies …


Hypertension Prevention Program And Its Effects On Blood Pressure Levels Among Young Adults In A Christian Community In Southwest Michigan, Cindel Hollancid Nov 2025

Hypertension Prevention Program And Its Effects On Blood Pressure Levels Among Young Adults In A Christian Community In Southwest Michigan, Cindel Hollancid

Doctor of Nursing Practice Projects

Background

Although the majority of patients who present are adults over the age of 40 years old; with blood pressures ranging from 140/88 – 190/110 and many times higher readings, it was intriguing and important to assess whether a direct intervention, teaching young adults ages 18 – 39 years the benefits of lifestyle choices would be beneficial as a preventative measure to implement for hypertension reduction patterns as one ages. According to Hinton et al. (2019), hypertension affects 1 in 8 adults between the ages of 20 and 40 years old and is thus common among young people; with the …


November 2025, Swosu Bulldog Wellness Committee Nov 2025

November 2025, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

  • SWOSU Wellness Fall 5k!
  • November is National Diabetes Month
  • The Wellness Committee has one desktop adjustable computer stand to loan out.
  • Spooktacular Step Challenge Results
  • November Word Search


Carroll County Advisory Council 2025, Mikayla Cerney Nov 2025

Carroll County Advisory Council 2025, Mikayla Cerney

UNH Cooperative Extension

No abstract provided.


Delayed Presentation Of A Retained Colonic Segment In A Child With Intestinal Failure On Teduglutide, Rachel C Bordelon, Sarah J Varalla, Varaha S Tammisetti, Mohamed M Shahin, Amanda Tchakarov, Essam Imseis, Allison L Speer Nov 2025

Delayed Presentation Of A Retained Colonic Segment In A Child With Intestinal Failure On Teduglutide, Rachel C Bordelon, Sarah J Varalla, Varaha S Tammisetti, Mohamed M Shahin, Amanda Tchakarov, Essam Imseis, Allison L Speer

Faculty, Staff and Student Publications

Teduglutide is a glucagon-like peptide 2 (GLP-2) analogue that was approved by the United States Food and Drug Administration for the treatment of pediatric (>1 year) intestinal failure due to short bowel syndrome in 2019. GLP-2 analogues promote rapid intestinal adaptation, increasing the absorptive capacity of residual intestine after surgical resection to aid the achievement of enteral autonomy or reduce parenteral nutrition requirements. Despite relatively few reported side effects, there is a theoretical risk of proliferative complications. Here we present an intriguing case of a pediatric patient found to have a decade-long retained, discontinuous segment of colon from a …


Prevalence Of Obesity With Confirmed Excess Adiposity In Us Children And Adolescents, Alexandra B Palmer, Kyung Hyun Lee, Rashedeh Roshani, Elizabeth Frankel, Miryoung Lee, Mohammad Y Anwar, Heather M Highland, Kristin L Young, Mariaelisa Graff, Joseph B Mccormick, Susan P Fisher-Hoch, Joyce P Samuel, Jennifer E Below, Kari E North, Penny Gordon-Larsen Nov 2025

Prevalence Of Obesity With Confirmed Excess Adiposity In Us Children And Adolescents, Alexandra B Palmer, Kyung Hyun Lee, Rashedeh Roshani, Elizabeth Frankel, Miryoung Lee, Mohammad Y Anwar, Heather M Highland, Kristin L Young, Mariaelisa Graff, Joseph B Mccormick, Susan P Fisher-Hoch, Joyce P Samuel, Jennifer E Below, Kari E North, Penny Gordon-Larsen

Faculty, Staff and Student Publications

No abstract provided.


The Role Of Fungal Proteases In Bioactive Peptide Production And Analytical Approaches For Tracking Their Activity, Tanvir Ahmed, Angéla Juhász, Utpal Bose, Netsane Shiferaw Terefe, Michelle L. Colgrave Nov 2025

The Role Of Fungal Proteases In Bioactive Peptide Production And Analytical Approaches For Tracking Their Activity, Tanvir Ahmed, Angéla Juhász, Utpal Bose, Netsane Shiferaw Terefe, Michelle L. Colgrave

Research outputs 2022 to 2026

Fungal proteases catalyse site-specific peptide bond cleavage in complex protein matrices, enabling bioactive peptide (BP) release. Accurate monitoring is vital for optimising hydrolysis efficiency, minimising nonspecific proteolysis, ensuring consistent yields, and preserving peptide biofunctionality. While analytical and computational tools are well-established for non-fungal systems, their adaptation to fungal proteases remains exploratory, with no comprehensive evaluation addressing the unique challenges in this field. This review synthesises current knowledge, identifies methodological gaps, and outlines future directions for developing fungi-specific analytical pipelines and computational frameworks for BP discovery. It explores fungal protease families, their roles in intracellular peptide processing, and fungal survival strategies. …


Prevalent Vertebral Fracture Is Associated With Incident Cardiovascular Disease Events In Older Individuals Referred For Bone Densitometry, John T. Schousboe, Barret A. Monchka, J. Michael Davidson, Douglas Kimelman, Syed Zulqarnain Gilani, Zaid Ilyas, Siobhan Reid, Joshua R. Lewis, William D. Leslie Nov 2025

Prevalent Vertebral Fracture Is Associated With Incident Cardiovascular Disease Events In Older Individuals Referred For Bone Densitometry, John T. Schousboe, Barret A. Monchka, J. Michael Davidson, Douglas Kimelman, Syed Zulqarnain Gilani, Zaid Ilyas, Siobhan Reid, Joshua R. Lewis, William D. Leslie

Research outputs 2022 to 2026

Background: It is unknown if prevalent vertebral fracture (PVFx) captured on bone density vertebral fracture assessment (VFA) images predicts incident CVD events. Methods: 11,760 individuals (mean [SD] age 75.7 [6.8] years, 94 % female) had VFA contemporaneously with bone densitometry in Manitoba, Canada, between February 2010 and December 2017, of whom 1919 (16.3 %) had ≥1 PVFx. This cohort was followed over a mean (SD) 3.8 (2.3) years for Major Adverse Cardiovascular Events (MACE, composite of hospitalization for myocardial infarction, non-hemorrhagic stroke, or all-cause mortality) and other CVD events (hospitalization for coronary artery disease, congestive heart failure, peripheral vascular disease, …


Determining The Accumulation Potential Of Nanoplastics In Crops: An Investigation Of 14C-Labelled Polystyrene Nanoplastic Into Radishes, Nathaniel J. Clark, Astrid C. Fischer, Demelza Carne, George R. Littlejohn, Lee J. Durndell, Anne Plessis, Richard C. Thompson Nov 2025

Determining The Accumulation Potential Of Nanoplastics In Crops: An Investigation Of 14C-Labelled Polystyrene Nanoplastic Into Radishes, Nathaniel J. Clark, Astrid C. Fischer, Demelza Carne, George R. Littlejohn, Lee J. Durndell, Anne Plessis, Richard C. Thompson

School of Biological and Marine Sciences

The capacity of crops to accumulate nanoplastics has remained relatively unexplored largely due to analytical constraints. To address this challenge, the present study employed a radiolabelling approach to demonstrate, for the first time, that polystyrene nanoplastics (14C-PS NPs) accumulate and move into the edible tissues of radishes (Raphanus sativus). Radishes were exposed hydroponically for five days, with only their non-fleshy roots in contact with the 14C-PS NPs, while accumulation in the fleshy (edible) roots and shoots was subsequently measured. The radish roots retained nearly 5 % of the 14C-PS NPs from the exposure, either through accumulation …


Global Cooling Watch 2025, Omar Abdelaziz, Ray Gluckman, Ian Hamilton, Radhika Khosla, Lily Riahi Nov 2025

Global Cooling Watch 2025, Omar Abdelaziz, Ray Gluckman, Ian Hamilton, Radhika Khosla, Lily Riahi

Research Collection College of Integrative Studies

The second edition of UNEP’s Global Cooling Watch Report takes a deep dive into one of the decade’s most urgent challenges: surging heat, soaring cooling demand, and stark inequalities in access. Produced by the UNEP-led Cool Coalition, the report provides a comprehensive assessment of the rapidly growing global demand for cooling and the need for climate-friendly solutions to the issue. The 2025 report builds on the first Global Cooling Watch (2023), which established the Sustainable Cooling Pathway framework. The new edition deepens analysis of intensifying extreme heat and its effect on cooling demand, improved assessment of passive cooling, and coverage …


Network-Based Multiomic Nutrient-Associated Predictive Models For Inflammatory Bowel Disease, Martine Saint-Cyr, Evaniya Shakya, Janet C Siebert, Emily B Hill, Nancy F Krebs, Edwin Dezoeten, Sarah J Borengasser Nov 2025

Network-Based Multiomic Nutrient-Associated Predictive Models For Inflammatory Bowel Disease, Martine Saint-Cyr, Evaniya Shakya, Janet C Siebert, Emily B Hill, Nancy F Krebs, Edwin Dezoeten, Sarah J Borengasser

2020-Current year OA Pubs

BACKGROUND: Inflammatory bowel disease (IBD) is a multifactorial disease involving a complex interplay between host physiology, the gut microbiome, and environmental factors such as diet and nutrition. Multiomic analyses may help to identify potential nutrient-associated omic predictors of IBD, allowing for the design of targeted dietary approaches for disease prevention and management.

OBJECTIVES: Our objective was to apply the bioinformatics tool, Consolidated Analysis of Network Topology and Regression Elements (CANTARE), to an integrated multiomics dataset to generate nutrient-associated predictive models for IBD.

METHODS: We previously used a published data set of microbiome relative abundance (mb), untargeted metabolomics (met), and microbial-derived …