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2025

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Strategic Leadership In Security Media: Enhancing Community Safety Against Drug Abuse In Oman, Raed Awashreh, Saif Alshuhoomi,, Viola Gjylbegaj Oct 2025

Strategic Leadership In Security Media: Enhancing Community Safety Against Drug Abuse In Oman, Raed Awashreh, Saif Alshuhoomi,, Viola Gjylbegaj

Journal of Strategic Security

Rapid global development has led to increased security challenges, particularly regarding drug-related crimes. This study examines the role of strategic leadership in security media to enhance community security, focusing on drug abuse in Oman. Despite ongoing efforts to combat drug-related offenses, these crimes remain a significant threat to societal stability. The qualitative research involved in-depth interviews with 14 decision-makers, including 7 experts from Oman’s security media, police, and related institutions. It explores the effectiveness of security media campaigns in raising awareness and reducing drug use. Thematic analysis of the data revealed key challenges, including limited resources, outdated technologies, and insufficient …


Unprecedented Polymicrobial Bacteremia With Nine Microorganisms In A Critically Ill 95% Burn Patient, Alexander Johnson, Julio Nasim, Brian B. Draper, Cindy L. Austin Oct 2025

Unprecedented Polymicrobial Bacteremia With Nine Microorganisms In A Critically Ill 95% Burn Patient, Alexander Johnson, Julio Nasim, Brian B. Draper, Cindy L. Austin

Student Publications

This report describes the case of a 21-year-old male with 95% total body surface area full-thickness burns who developed polymicrobial bacteremia involving nine distinct bacterial species, the highest number of diverse bacterial species documented to simultaneously coexist in a patient’s bloodstream. Despite aggressive surgical, antimicrobial, and multidisciplinary interventions, the patient succumbed to sepsis after 12 days. The case highlights the diagnostic and therapeutic challenges of managing complex infections in burn patients and underscores the critical importance of early detection, prompt treatment, and coordinated care. A literature review of the identified pathogens provides context and reveals notable findings relevant to this …


Cattle Funding Scheme 2023-24 Annual Report, Department Of Primary Industries And Regional Development, Western Australia Oct 2025

Cattle Funding Scheme 2023-24 Annual Report, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity published reports

I am pleased to present the 2023-24 annual report for the Cattle Industry Funding Scheme (Cattle IFS) to our participants, key stakeholders in the Western Australian (WA) cattle industry, and the Minister for Agriculture and Food. This financial year has brought its share of challenges to the WA cattle industry including domestic and global markets, dry weather conditions and high biosecurity concerns. With Foot-and-mouth disease (FMD) and Lumpy Skin Disease (LSD) detected in Indonesia, biosecurity threats remain ever-present. As a result, maintaining the health of our herd in WA continues to be our top priority. The Cattle IFS continues to …


Exposure To Household Air Pollution From Biomass Cooking And Severe Pneumonia In Infants, John P Mccracken, Lindsay J Underhill, Et Al. Oct 2025

Exposure To Household Air Pollution From Biomass Cooking And Severe Pneumonia In Infants, John P Mccracken, Lindsay J Underhill, Et Al.

2020-Current year OA Pubs

IMPORTANCE: Household air pollution from biomass cooking is considered an important risk factor for child pneumonia.

OBJECTIVE: To evaluate the longitudinal association between exposure to particulate matter with a diameter of less than or equal to 2.5 µm (PM2.5) or carbon monoxide (CO) and severe pneumonia in infants.

DESIGN, SETTING, AND PARTICIPANTS: This cohort study included infants (aged ≤12 months) whose mothers participated in a 4-country randomized clinical trial. Conducted from May 2018 to September 2021, the trial tested whether an 18-month liquefied petroleum gas stove and fuel distribution intervention reduced the incidence of severe pneumonia in offspring during infancy …


Mapping The Geographic Distribution Of Dimorphic Mycoses Using A Us Commercial Insurance Database, Reid Goodman, Adriana M Rauseo, Samuel L Windham, Julio C Zuniga-Moya, William G Powderly, Andrej Spec, Patrick B Mazi Oct 2025

Mapping The Geographic Distribution Of Dimorphic Mycoses Using A Us Commercial Insurance Database, Reid Goodman, Adriana M Rauseo, Samuel L Windham, Julio C Zuniga-Moya, William G Powderly, Andrej Spec, Patrick B Mazi

2020-Current year OA Pubs

BACKGROUND: The dimorphic mycoses (DMs) histoplasmosis, blastomycosis, and coccidioidomycosis are classically thought to be geographically restricted to specific regions of the United States. The current scientific consensus is that these geographic boundaries are expanding, but the extent of this expansion remains uncertain.

METHODS: This study is a retrospective analysis of >21 million (annually) commercially insured individuals within the United States during 2007-2016. Diagnosis of histoplasmosis, coccidioidomycosis, and blastomycosis were identified using

RESULTS: There were 37 513 histoplasmosis, 14 987 coccidioidomycosis, and 2207 blastomycosis diagnoses during 2007-2016 within 387 Metropolitan Statistical Areas. DMs were consistently diagnosed outside their historical hyperendemic regions. …


Data-Driven Optimization And Parameter Estimation For A Metric Graph Epidemic Model With Applications To Covid-19 Spread In Poland: A Real-World Example Of Optimization For A Challenging Rosenbrock-Type Objective Function, Hannah Kravitz, Christina Duron, Brittani Nieves, Moysey Brio Oct 2025

Data-Driven Optimization And Parameter Estimation For A Metric Graph Epidemic Model With Applications To Covid-19 Spread In Poland: A Real-World Example Of Optimization For A Challenging Rosenbrock-Type Objective Function, Hannah Kravitz, Christina Duron, Brittani Nieves, Moysey Brio

Mathematics and Statistics Faculty Publications and Presentations

In this paper, we apply data-driven optimization to estimate key parameters in a metric graph-based epidemiological model, with the aim of analyzing the effect of road networks on the geographic spread of epidemics. As a case study, we fit our model to data from the COVID-19 pandemic in Poland during 2021. Our dataset integrates county-level daily case reports, national census information, and traffic flow studies. This framework allows us to examine the relative contribution of specific travel routes over time and infer unobserved transmission patterns in the presence of incomplete or unreliable case reporting. The optimization problem that arises from …


Liver-Specific Expression Of Hiv-1 Viral Protein R Causes Hepatic Steatosis And Glucose Intolerance In Male Mice, Neeti Agarwal, Pradip Saha, Claudia E Ramirez Bustamante, Sean M Hartig, Mark A Herman, Ashok Balasubramanyam, Jordan E Lake Oct 2025

Liver-Specific Expression Of Hiv-1 Viral Protein R Causes Hepatic Steatosis And Glucose Intolerance In Male Mice, Neeti Agarwal, Pradip Saha, Claudia E Ramirez Bustamante, Sean M Hartig, Mark A Herman, Ashok Balasubramanyam, Jordan E Lake

Faculty, Staff and Students Publications

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly recognized in people with HIV (PWH), with both HIV and antiretroviral therapy contributing to liver damage and glucose intolerance. However, the role of viral proteins derived from reservoirs in this process remains unclear.

Methods: Adeno-associated virus (AAV) constructs encoding a control protein or HIV-1 viral protein R (Vpr) driven by the thyroxine-binding globulin promoter were administered to male mice (n = 5 per group) fed regular chow or a high-fat diet (HFD). Young adult mice underwent intraperitoneal glucose tolerance testing and magnetic resonance imaging, followed by euthanasia. Liver and adipose tissues …


Covid-19 Booster Vaccine Messaging In Emergency Departments: A Cluster Randomized Clinical Trial, Melanie F Molina, Stephanie A Eucker, Kristin L Rising, Efrat R Kean, Zubaid Rafique, Heba Mesbah, David V Glidden, Mireya I Arreguin, Christopher Alvarez, Robert M Rodriguez Oct 2025

Covid-19 Booster Vaccine Messaging In Emergency Departments: A Cluster Randomized Clinical Trial, Melanie F Molina, Stephanie A Eucker, Kristin L Rising, Efrat R Kean, Zubaid Rafique, Heba Mesbah, David V Glidden, Mireya I Arreguin, Christopher Alvarez, Robert M Rodriguez

Faculty, Staff and Students Publications

Importance: Patient uptake of updated COVID-19 vaccines is crucial for reducing severe outcomes, yet national uptake remains low.

Objective: To determine if tailored messaging or simple inquiry about vaccine acceptance increases 30-day uptake of updated COVID-19 vaccines among emergency department (ED) patients.

Design, setting, and participants: This 3-arm, cluster randomized clinical trial conducted from January 29 to June 18, 2024, enrolled adult ED patients who had not received a COVID-19 vaccine in the prior 6 months across 6 EDs in San Francisco, California; Philadelphia, Pennsylvania; Houston, Texas; and Durham, North Carolina.

Interventions: Intervention M involved tailored messaging about updated COVID-19 …


Shrimp Allergy-Distinct Allergen Sensitization Profiles Between Intercontinental Cohorts, Shaymaviswanathan Karnaneedi, Sara Anvari, Shea Brunner, Karen S Tuano, Brenda Bin Su, Saachi Hira, Sahel Heidari, Diamond Hira, Carla M Davis, Andreas L Lopata Oct 2025

Shrimp Allergy-Distinct Allergen Sensitization Profiles Between Intercontinental Cohorts, Shaymaviswanathan Karnaneedi, Sara Anvari, Shea Brunner, Karen S Tuano, Brenda Bin Su, Saachi Hira, Sahel Heidari, Diamond Hira, Carla M Davis, Andreas L Lopata

Faculty, Staff and Students Publications

No abstract provided.


Cutaneous Tuberculosis With Multisystem Involvement In An Immunocompetent Refugee, Nabor S Mireles, Natalie Garcia, Omid Jalali Oct 2025

Cutaneous Tuberculosis With Multisystem Involvement In An Immunocompetent Refugee, Nabor S Mireles, Natalie Garcia, Omid Jalali

Faculty, Staff and Students Publications

Cutaneous tuberculosis (CTB) is an uncommon skin infection that can mimic other dermatologic conditions and delay recognition. Herein, we present a case of TB chancre, a form of CTB caused by exogenous inoculation. A 19-year-old immunocompetent male refugee from Sudan presented with a five-month history of non-healing wounds on his right shoulder and three weeks of bilateral lower extremity weakness. Diagnostic examination revealed the presence of a spinal epidural abscess and lung consolidation, with culture of the spinal abscess positive for Mycobacterium tuberculosis (MTB). Skin biopsy of the shoulder lesion revealed granulomatous dermatitis, with subsequent culture confirming MTB from the …


Inhibition Of Ros1 Activity With Lorlatinib Reversibly Suppresses Fertility In Male Mice, Yuki Oyama, Kentaro Shimada, Haruhiko Miyata, Rie Iida-Norita, Chihiro Emori, Maki Kamoshita, Seiya Oura, Ryohei Katayama, Martin M Matzuk, Masahito Ikawa Oct 2025

Inhibition Of Ros1 Activity With Lorlatinib Reversibly Suppresses Fertility In Male Mice, Yuki Oyama, Kentaro Shimada, Haruhiko Miyata, Rie Iida-Norita, Chihiro Emori, Maki Kamoshita, Seiya Oura, Ryohei Katayama, Martin M Matzuk, Masahito Ikawa

Faculty, Staff and Students Publications

Background: Inhibition of sperm maturation in the epididymis is a promising post-testicular strategy for short-acting male contraceptives. It has been shown that ROS1, a receptor tyrosine kinase expressed in the epididymis, is essential for epididymal differentiation, sperm maturation, and male fertility in mice. However, it is unknown if inhibition of ROS1 suppresses male fertility reversibly.

Objectives: Our study aimed to investigate the effects of ROS1 inhibitor administration in male mice on sperm function and fertility.

Materials and methods: We used lorlatinib, an anti-cancer drug that inhibits ROS1. We treated 10-week-old sexually mature male mice with lorlatinib for 3 weeks and …


Nrf2 Hyperactivation As A Driver Of Radiotherapy Resistance And Suppressed Antitumor Immunity In Head And Neck Squamous Cell Carcinoma, Rutulkumar Patel, Kalil Saab, Lixia Luo, Yan Ma, Rashid Abdullah Osman, Nerissa T Williams, Jeffrey Everitt, Maciej J Zelazowski, Patricia Castro, William K Decker, William H Hudson, Jeffrey N Myers, Vlad C Sandulache, Mitchell J Frederick, Yvonne M Mowery, David G Kirsch Oct 2025

Nrf2 Hyperactivation As A Driver Of Radiotherapy Resistance And Suppressed Antitumor Immunity In Head And Neck Squamous Cell Carcinoma, Rutulkumar Patel, Kalil Saab, Lixia Luo, Yan Ma, Rashid Abdullah Osman, Nerissa T Williams, Jeffrey Everitt, Maciej J Zelazowski, Patricia Castro, William K Decker, William H Hudson, Jeffrey N Myers, Vlad C Sandulache, Mitchell J Frederick, Yvonne M Mowery, David G Kirsch

Faculty, Staff and Students Publications

Purpose: Alterations in the KEAP1/NFE2L2 (NRF2)/CUL3 pathway occur in ∼20% of human head and neck squamous cell carcinomas (HNSCC) and are associated with resistance to standard-of-care therapy. However, this pathway's role in radiotherapy resistance in HNSCC has not been well studied.

Experimental design: We generated genetically engineered mouse models and developed primary murine cancer cell lines harboring mutations commonly observed in human HNSCC, including inducible activation of PIK3CA and deletion of Trp53, with or without Keap1 loss. Primary tumors were initiated via 4-hydroxytamoxifen injection ± the tobacco carcinogen benzo[a]pyrene (BAP) into the oral buccal mucosa. Tumors were analyzed by Western …


Leveraging De-Implementation Science To Promote Infection Prevention And Stewardship: A Roadmap And Practical Examples (Part Ii Of Ii), Westyn Branch-Elliman, Jennie H Kwon, Et Al. Oct 2025

Leveraging De-Implementation Science To Promote Infection Prevention And Stewardship: A Roadmap And Practical Examples (Part Ii Of Ii), Westyn Branch-Elliman, Jennie H Kwon, Et Al.

2020-Current year OA Pubs

De-implementation of established practices is a common challenge in infection prevention and antimicrobial stewardship and a necessary part of the life cycle of healthcare quality improvement programs. Promoting de-implementation of ineffective antimicrobial use and increasingly of low-value diagnostic testing are cornerstones of stewardship practice. Principles of de-implementation science and the interplay of implementation and de-implementation are discussed in part I of this Society for Healthcare Epidemiology of America White Paper Series.In this second part of the series, we discuss a process for applying principles of de-implementation science in infection prevention and stewardship and then review some real-world examples and case …


Molecular Dynamics Of The Host Response To Streptococcus Pneumoniae Pneumonia In Baboons, Bryan D Kraft, Et Al. Oct 2025

Molecular Dynamics Of The Host Response To Streptococcus Pneumoniae Pneumonia In Baboons, Bryan D Kraft, Et Al.

2020-Current year OA Pubs

BACKGROUND: Bacterial pneumonia remains a leading cause of morbidity and mortality worldwide despite the widespread availability of antibiotics. Novel pneumonia therapies and biomarkers are urgently needed to improve outcomes and advance personalized therapy. Using an established baboon model of S. pneumoniae pneumonia, we sought to characterize the temporal dynamics of pneumonia host responses to identify novel potential diagnostic and therapeutic molecular targets.

METHODS: We performed whole blood transcriptomics, unbiased proteomics, and peripheral cytokine measurements serially in baboons inoculated with S. pneumoniae (n = 23) or saline (n = 10) and modeled the peripheral blood host response using principal components analysis …


Motivations, Facilitators, And Barriers Of Donation-Based Interventions In Hiv And Sexually Transmitted Infection Research: A Systematic Review, Dorian Ho, Ye Liu, Jamie Conklin, Thomas Fitzpatrick, Jiayu Wang, Suzanne Day, Takhona G Hlatshwako, Rohit Ramaswamy, Ruby Congjiang Wang, Eneyi E Kpokiri, Weiming Tang, Elvin Geng, Joseph D Tucker Oct 2025

Motivations, Facilitators, And Barriers Of Donation-Based Interventions In Hiv And Sexually Transmitted Infection Research: A Systematic Review, Dorian Ho, Ye Liu, Jamie Conklin, Thomas Fitzpatrick, Jiayu Wang, Suzanne Day, Takhona G Hlatshwako, Rohit Ramaswamy, Ruby Congjiang Wang, Eneyi E Kpokiri, Weiming Tang, Elvin Geng, Joseph D Tucker

2020-Current year OA Pubs

IMPORTANCE: Donation-based prosocial interventions involve someone receiving a free health service and then distributing or donating to support health services for others; examples within the HIV and sexually transmitted infection (STI) literature include secondary distribution of HIV self-tests, secondary syringe exchange, and pay it forward for STI testing. These interventions answer research and policy recommendations to incorporate prosocial behaviors into HIV/STI services.

OBJECTIVE: To describe motivations, facilitators, and barriers of donation-based interventions in HIV and STI research using data from qualitative studies.

EVIDENCE REVIEW: In this systematic review, 5 databases (PubMed, CINAHL, Embase, PsycInfo, and Scopus) and references were searched …


Evaluating The Impact Of The ‘Blow, Breathe, Cough’ Health Promotion Intervention In Resolving Otitis Media With Effusion In Children: An Adaptive Randomized-Controlled Trial Protocol, Jaimee R. Rich, Michael Dymock, Elke J. Seppanen, Elena Montgomery, Tanisha Cayley, Tamara Veselinović, Greta Bernabei, Anri Lester, Amy Hannigan, Nicole Irvine, Kerryn Gidgup, Edna Ninyette, Steph Bray, Tu Trang Tran, Valerie M. Swift, Melinda Edmunds, Natalie Strobel, Daniel Mcaullay, Julie Marsh, Evelyn Tay, Lea Ann S. Kirkham, Ruth B. Thornton, Robyn S.M. Choi Oct 2025

Evaluating The Impact Of The ‘Blow, Breathe, Cough’ Health Promotion Intervention In Resolving Otitis Media With Effusion In Children: An Adaptive Randomized-Controlled Trial Protocol, Jaimee R. Rich, Michael Dymock, Elke J. Seppanen, Elena Montgomery, Tanisha Cayley, Tamara Veselinović, Greta Bernabei, Anri Lester, Amy Hannigan, Nicole Irvine, Kerryn Gidgup, Edna Ninyette, Steph Bray, Tu Trang Tran, Valerie M. Swift, Melinda Edmunds, Natalie Strobel, Daniel Mcaullay, Julie Marsh, Evelyn Tay, Lea Ann S. Kirkham, Ruth B. Thornton, Robyn S.M. Choi

Research outputs 2022 to 2026

Introduction: Otitis media with effusion (OME) affects hearing, speech development, and quality of life (QoL) in children. The ‘Blow, Breathe, Cough’ (BBC) intervention promotes nasal, respiratory, and middle ear clearance through nose blowing, deep breathing, coughing, and hand hygiene. It shows promise in resolving OME but lacks randomized-controlled trial (RCT) evaluation. This paper presents a RCT protocol evaluating BBC's effect on OME resolution, hearing, speech, and QoL in children aged two to seven years. Methods: This parallel-group, 1:1, outcome assessor-blinded, individual adaptive RCT investigates whether completing the BBC intervention plus hand hygiene twice-daily at home increases OME resolution after 4-to-6 …


Omani Endogenous Plants: A Review Of Phytochemical Analysis And Antioxidant Activities, Al Aufi Najwa, Waly I. Mostafa Sep 2025

Omani Endogenous Plants: A Review Of Phytochemical Analysis And Antioxidant Activities, Al Aufi Najwa, Waly I. Mostafa

Journal of Agricultural and Marine Sciences

Herbal medicines have been used for centuries across various cultures to treat a wide range of illnesses. In recent years, growing research supports the bioactive properties of medicinal plants, including antibacterial, antioxidants, antiviral, anticancer, and antimicrobial activities. This review focuses on seven common endogenous Omani plants—Rumex vesicarius (Humeidh), Pteropyrum scoparium (Sidaf), Haplophyllum tuberculatum (Sazab or Sinan al-Tais), Portulaca oleracea (Baqla or Rjla/Purslane), Fagonia indica (Al-Shukaa), Dodonaea viscosa (Shatt), and Prosopis cineraria (Al Ghaf)—and evaluates their antioxidant and phytochemical properties in the context of chronic disease prevention. The findings highlight the potential of these plants as natural alternatives for managing chronic …


Antibiotic Resistance Trends In Coliform Bacteria Of Kittitas County Waters, Kaitlyn Holbrook, Bella Blasingim, Cruz Veronica Guillen Mejia, Holly Pinkart Sep 2025

Antibiotic Resistance Trends In Coliform Bacteria Of Kittitas County Waters, Kaitlyn Holbrook, Bella Blasingim, Cruz Veronica Guillen Mejia, Holly Pinkart

Journal of the Symposium of University Research and Creative Expression

Project Mentor(s): Holly Pinkart, PhD

Since the mid-1900s, antibiotics have been developed to help fight against bacterial pathogens. However, bacteria can evolve rapidly and have evolved resistance to many types of antibiotics. Using coliform bacteria collected from waters around Kittitas County, BIOL 323 students at Central Washington University have identified a variety of antibiotic-resistant bacteria in Kittitas County streams and canals. Antibiotic resistance was measured from 2014-2019 and compared to data collected in 2024. This study focuses on three antibiotics, ampicillin, kanamycin, and trimethoprim-sulfamethoxazole. In the past (2014-2019) we saw no change in the trend of antibiotic resistance in collected …


Risk Factors For Tuberculosis (Tb) Treatment Interruption Among New And Retreatment Tb Patients In West Kalimantan Province, Indonesia: A Retrospective Cohort Study, Agus Fitriangga, Alex Alex, Rita Aryati Sep 2025

Risk Factors For Tuberculosis (Tb) Treatment Interruption Among New And Retreatment Tb Patients In West Kalimantan Province, Indonesia: A Retrospective Cohort Study, Agus Fitriangga, Alex Alex, Rita Aryati

Journal of Health Research

Background: Treatment adherence in tuberculosis (TB) remains a major public health challenge in Indonesia. In West Kalimantan, high treatment interruption rates are driven by geographic, socioeconomic, and healthcare factors. This study identifies the risk factors linked to treatment interruption in the province.

Methods: A retrospective cohort study was using the System Information of Tuberculosis (SITB) database from 2019 to 2022 (n = 12,052). We used Kaplan-Meier analysis and Cox regression to identify treatment interruption risk factors, considering patient characteristics and geographic disparities.

Results: The overall treatment interruption rate was 6.62 % among new patients and 2.87 % among retreatment …


Taking Control Of Reproductive Health Information: Behind The Scenes With A Cataloging Librarian, Tanesa G. King Sep 2025

Taking Control Of Reproductive Health Information: Behind The Scenes With A Cataloging Librarian, Tanesa G. King

Library Scholarship

With the overturning of Roe v. Wade in June 2022, the author saw a need for an assessment of her institutional library’s collection of resources about reproductive and sexual health, especially on topics related to abortion and birth control. The author worked as a cataloging librarian in Texas at the time and anticipated that patrons would turn to the library for information about reproductive matters and thought a project concerning the reproductive and sexual health collection was vital for her library. Ensuring that the library catalog provided adequate subject access to the reproductive health resources that library users need, as …


Ready For Takeoff? Exploring United States Health Care Providers’ Pretravel Consultation Priorities, Gaps, Barriers, And Opportunities, Katherine A. Reifler, Swati S. Sharma, Nicholas A. Bergren, Elizabeth D. Barnett, Lin H. Chen, Jeffery A. Goad, William B. Macleod, Laura Kogelman, Davidson H. Hamer Sep 2025

Ready For Takeoff? Exploring United States Health Care Providers’ Pretravel Consultation Priorities, Gaps, Barriers, And Opportunities, Katherine A. Reifler, Swati S. Sharma, Nicholas A. Bergren, Elizabeth D. Barnett, Lin H. Chen, Jeffery A. Goad, William B. Macleod, Laura Kogelman, Davidson H. Hamer

Pharmacy Faculty Articles and Research

Pretravel consultation by healthcare providers (HCPs) with travel medicine expertise can mitigate travel-related health risks. This analysis aimed to understand US-based HCPs' pretravel consultation educational gaps, priorities, barriers, and opportunities. An electronic survey was conducted May–June 2024, using a convenience sample of HCPs identified through the Med Learning Group and travel specialists from the International Society of Travel Medicine and American Society of Tropical Medicine and Hygiene. In total, 205 HCPs completed the survey, including physicians (50 %), nurse practitioners (19 %), nurses (12 %), pharmacists (11 %), physician associates (7 %). Most (66 %) provided pretravel consultations and only …


Dynamics And Optimal Intervention Strategies In A Shigellosis Transmission Model, Mehmet Gümüs, Shewafera Wondimagegnhu Teklu, Kemal Türk Sep 2025

Dynamics And Optimal Intervention Strategies In A Shigellosis Transmission Model, Mehmet Gümüs, Shewafera Wondimagegnhu Teklu, Kemal Türk

Mathematical Modelling and Numerical Simulation with Applications

This research explores how water treatment contributes to limiting the transmission of Shigellosis, an infection caused by bacteria from the Shigella genus. A mathematical framework is formulated to evaluate the influence of protective strategies and water purification on the spread of the disease. To confirm the model's biological relevance, its well-posedness is investigated. The basic reproduction number $(\mathfrak{R}_0)$, a critical indicator of disease behavior, is derived using the matrix operator method. Findings indicate that if $\mathfrak{R}_01$, the infection persists, with the endemic equilibrium exhibiting local asymptotic stability. A comprehensive cost-effectiveness analysis reveals that combining environmental protection with water treatment represents …


Htlv-1 And Atll: Epidemiology, Oncogenesis, And Opportunities For Community-Informed Research In The United States, Adrian D. Altieri, Sean P. Reilly, Abu Mansalay, Alan Khoo, Nettie Johnson, Zafar K. Khan, Amy Leader, Pooja Jain, Pierluigi Porcu Sep 2025

Htlv-1 And Atll: Epidemiology, Oncogenesis, And Opportunities For Community-Informed Research In The United States, Adrian D. Altieri, Sean P. Reilly, Abu Mansalay, Alan Khoo, Nettie Johnson, Zafar K. Khan, Amy Leader, Pooja Jain, Pierluigi Porcu

Kimmel Cancer Center Faculty Papers

Human T-cell leukemia virus type 1 (HTLV-1), the first oncogenic human retrovirus, causes adult T-cell leukemia/lymphoma (ATLL), an aggressive neoplasm of mature CD4+ T-cells that is incurable in most patients and is associated with a median survival of less than 1 year. HTLV-1 also causes inflammatory disorders, including HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and uveitis. The estimated lifetime risks of ATLL and HAM/TSP in HTLV-1 carriers are 3-5% and 0.25-1.8%, respectively. Although there is uncertainty about other health effects of HTLV-1, a recent meta-analysis showed an association between HTLV-1 and cardiovascular, cerebrovascular, and metabolic diseases and a 57% increased risk …


Review On Exploring The Potential Of Black Soldier Fly (Hermetia Illucens) As A Novel Feed Ingredient For Poultry, Muhammad Naeem Jan, Nasir Rajput, Muhammad Naeem, Sher Ali, Ghulam Shabir Barham, Tehseen Fatima Miano Sep 2025

Review On Exploring The Potential Of Black Soldier Fly (Hermetia Illucens) As A Novel Feed Ingredient For Poultry, Muhammad Naeem Jan, Nasir Rajput, Muhammad Naeem, Sher Ali, Ghulam Shabir Barham, Tehseen Fatima Miano

Journal of Bioresource Management

Poultry provides both direct and indirect employment opportunities to individuals. Every farm owner desires a reduced investment with more earnings. Over 50 % of the overall cost of chicken rearing is allocated to feed stuff. Among all feed ingredients, protein sources are the most expensive, yet protein is essential for production and growth. This exorbitant price cannot be sustained by the small-scale farmers. Consequently, contemporary scientists are attempting to substitute the protein supply with black soldier fly in their formulations. This review study examines the advantageous effect of utilizing Black Soldier Fly powder, larvae or oil, as demonstrated in scientific …


A Review On The Ethnozoological Remedies With The Help Of Animal Body Parts And Its Impact On Their Conservation Status, Minahal Fatima, Bushra Nisar Khan, Mudasser Hasan, Amina Tufail, Farhat Batool, Majida Maqbool, Fakhra Nazir Sep 2025

A Review On The Ethnozoological Remedies With The Help Of Animal Body Parts And Its Impact On Their Conservation Status, Minahal Fatima, Bushra Nisar Khan, Mudasser Hasan, Amina Tufail, Farhat Batool, Majida Maqbool, Fakhra Nazir

Journal of Bioresource Management

The use of wildlife in biomedical science has had a long history as it has been used as experimental animals, Sources of unusual physiology, and of bioactive compounds on which life-saving medicines are based. Amphibians are a Source of antimicrobial peptides, analgesic alkaloids, and regeneration. Immune adaptations and venoms of reptiles have produced cardiovascular medications, anti-clotting solutions and diabetes treatment. Birds serve as models of zoonotic diseases and provide immunological tools e.g. IgY antibodies and support embryology and neurobiology. Advanced studies on human disease, vaccines, cancer resistance and hypoxia tolerance have been facilitated by mammals such as rodents, primates, bats, …


Spartan Daily, September 30, 2025, San Jose State University, School Of Journalism And Mass Communications Sep 2025

Spartan Daily, September 30, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 16


Electronic Device Usage During Covid-19 And Suspected Developmental Delay In Rural Thai Children: A Case-Control Study, Kunnara Maneekunwong, Pimkanabhon Trakooltorwong, Salisa Kodyee, Nathamon Wutthipan, Chompunut Sopajaree, Katemanee Moonpanane Sep 2025

Electronic Device Usage During Covid-19 And Suspected Developmental Delay In Rural Thai Children: A Case-Control Study, Kunnara Maneekunwong, Pimkanabhon Trakooltorwong, Salisa Kodyee, Nathamon Wutthipan, Chompunut Sopajaree, Katemanee Moonpanane

Asia-Pacific Social Science Review

The COVID-19 pandemic has significantly altered the way in which people interact with and use technology, particularly in early childhood. This study investigated the relationship between electronic device usage during the COVID-19 pandemic in rural Thailand and suspected developmental delay (SDD) in early childhood. A case-control study aimed to investigate the relationship between suspected SDD and electronic device usage among children aged 2–5 and their primary caregivers in Chiang Rai province, Thailand. The cases were children with SDD, whereas the controls were children with age-appropriate development. The Developmental Surveillance and Promotion Manual (DSPM) and the Screen Media Exposure (SME) questionnaire …


Whose Burden, Whose Benefit? Revisiting Ethical Trade-Offs In The Who Guidelines On Scaling Up Mass Azithromycin Administration, Maple Goh, A. M. Viens, Safura Abdool Karim, Aaron S. Kesselheim, Kevin Outterson Sep 2025

Whose Burden, Whose Benefit? Revisiting Ethical Trade-Offs In The Who Guidelines On Scaling Up Mass Azithromycin Administration, Maple Goh, A. M. Viens, Safura Abdool Karim, Aaron S. Kesselheim, Kevin Outterson

Faculty Scholarship

Author summary

  • New evidence suggests that mass drug administration of azithromycin (MDAA) can significantly reduce childhood mortality in high-burden, low-resource settings, yet the World Health Organization’s (WHO) 2020 guidelines take a cautious approach due to concerns about antimicrobial resistance (AMR).
  • While the WHO guidelines cite ethical principles, they insufficiently address key considerations, such as intergenerational justice, equitable burden sharing, and the structural determinants of health that shape infectious disease vulnerability.
  • Global AMR policy often prioritizes conservation over access in ways that disproportionately burden low-income countries, despite high-income countries also bearing significant responsibility for the emergence and spread of AMR.
  • A …


Adaptation Of Moringa Leaf Extract On Hemoglobin And Arm Circumference In Adolescent Girls Semarang, Sri Achadi Nugraheni, Ari Yuniastuti, Suryani As’Ad, Pingkan Fristiwi, Fatimah Asri Fadhilah Aulia, Shafa Alya Kamila Sep 2025

Adaptation Of Moringa Leaf Extract On Hemoglobin And Arm Circumference In Adolescent Girls Semarang, Sri Achadi Nugraheni, Ari Yuniastuti, Suryani As’Ad, Pingkan Fristiwi, Fatimah Asri Fadhilah Aulia, Shafa Alya Kamila

Media Kesehatan Masyarakat Indonesia

Adolescent malnutrition, particularly anemia, remains a major public health challenge in developing countries, including Indonesia, as it increases the risk of growth retardation, developmental disorders, poor pregnancy outcomes, and infectious diseases. Nutritional interventions during adolescence are crutial for improving health and breaking the intergenerational cycle of malnutrition. This study aimed to analyze the effect of Moringa oleifera capsules on hemoglobin (Hb) levels and Mid-Upper Arm Circumference (MUAC) among adolescent girls in Semarang. A quasi-experimental study with a pretest–posttest control group design was conducted in two junior high schools in Semarang (SMPN 39 and SMPN 8), involving 102 female students aged …


Strongyloides Seropositivity Among Children Utilizing A Mobile Clinic, Lynda Aririguzo, Aditi Gupta, Norma Castillo, Cassandra Duran, Eva H Clark, Ankona Banerjee, Sanghamitra Misra Sep 2025

Strongyloides Seropositivity Among Children Utilizing A Mobile Clinic, Lynda Aririguzo, Aditi Gupta, Norma Castillo, Cassandra Duran, Eva H Clark, Ankona Banerjee, Sanghamitra Misra

Faculty, Staff and Students Publications

Experts recommend screening for or presumptively treating strongyloidiasis in foreign-born immigrant children, though prevalence is unknown. Health care providers encounter barriers to following this recommendation. We aimed to describe Strongyloides seropositivity and risk factors among pediatric patients on a mobile clinic. Participants completed a written survey and provided blood for absolute eosinophil count (AEC) and Strongyloides IgG enzyme-linked immunosorbent assay (ELISA). From October 2022 to June 2023, 206 patients participated; 201 (97.6%) were born outside the United States; 97.1% (n = 200) were Hispanic. Most (68.9%) arrived less than 1 year before study enrollment. Four (1.9%) and 3 (1.5%) had …