Digital Commons Network^™

Impact Of Elevated Serum Triglycerides On Children With Acute Recurrent Or Chronic Pancreatitis From Insppire-2, Zachary M Sellers, Matthew J Giefer, Fuchenchu Wang, Gretchen A Cress, Maisam A Abu-El-Haija, Ankur Chugh, Reuven Z Cohen, Elissa M Downs, Douglas S Fishman, A Jay Freeman, Cheryl E Gariepy, Tanja Y Gonska, Amit S Grover, Doug Lindblad, Quin Y Liu, Asim Maqbool, Jacob A Mark, Brian A Mcferron, Megha S Mehta, Veronique D Morinville, Kenneth Ng, Robert A Noel, Chee Y Ooi, Emily R Perito, Madhura Y Phadke, Wenly Ruan, Sarah Jane Schwarzenberg, David M Troendle, Michael Wilschanski, Yuhua Zheng, Ying Yuan, Mark E Lowe, Aliye Uc, Consortium For The Study Of Chronic Pancreatitis, Diabetes And Pancreatic Cancer

Faculty, Staff and Students Publications

Objective: To determine if mild-moderate hypertriglyceridemia (HTG) is associated with increased development of chronic pancreatitis (CP) or pancreatitis-associated complications in children with acute recurrent or CP.

Study design: Longitudinal data from the INternational Study group of Pediatric Pancreatitis: In search for a cuRE-2 (INSPPIRE-2) cohort of children with acute recurrent or CP (n = 559) were analyzed. Subjects were divided into normal triglycerides (< 150 mg/dL; 1.7 mmol/L), any HTG (≥150 mg/dL; ≥1.7 mmol/L), mild-moderate HTG (150-499 mg/dL; 1.7-5.6 mmol/L), moderate HTG (500-999 mg/dL; 5.6-11.3 mmol/L), and severe HTG groups (≥1000 mg/dL; ≥11.3 mmol/L), based on highest serum triglyceride value. Laboratory, imaging, pancreatitis and hospital events, complications, and quality of life data were analyzed.

Results: In children with acute recurrent or CP and HTG, there was no increase in the number of pancreatitis attacks per person-years, nor an increase in CP prevalence. However, HTG severity was associated with increased pancreatic …

Correction: Inclusion Of Patient-Centered, Non-Microbiological Endpoints And Biomarkers In Tuberculosis Drug Trials, Andrew R Dinardo, Wilbert Sabiiti, Stephen H Gillespie, Sophia B Georghiou, Norbert Heinrich, Norbert Hittel, Sami Taghlabi, Danna Carrero Longlax, Mikashmi Kohli, Ursula Panzner, Collins Musia, Christoph Lange, Anca Vasiliu, Rob J W Arts, Anna M Mandalakas, Morten Ruhwald, Lieven J Stuyver, Reinout Van Crevel

Faculty, Staff and Students Publications

This corrects the article "Inclusion of patient-centered, non-microbiological endpoints and biomarkers in tuberculosis drug trials", 1570989.

Towards A Common Approach For Managing Food Allergy And Serious Allergic Reactions (Anaphylaxis) At School. Ga2len And Efa Consensus Statement, Antoine Deschildre, Montserrat Alvaro-Lozano, Antonella Muraro, Marcia Podesta, Debra De Silva, Mattia Giovannini, Simona Barni, Timothy E Dribin, Mónica Sandoval-Ruballos, Aikaterini Anagnostou, Alessandro Fiocchi, Alice Toniolo, Andrew Bird, Angel Sánchez Sanz, Anna Asarnoj, Anna Nowak-Wegrzyn, Berber Vlieg-Boerstra, Brian P Vickery, Carina Venter, Caroline Nilsson, Cecilia Parente, Céline Demoulin, David M Fleischer, Diola Bijlhout, Edward F Knol, Eleanor Garrow, Emma E Cook, Fallon Schultz, Francesca Lazzarotto, Francesca Mori, Gary Wong, Gideon Lack, Graham Roberts, Gustavo Andres Marino, H N G Oude Elberink, Helen A Brough, Hugh A Sampson, Jay Lieberman, Jennifer Gerdts, Jing Zhao, Josefine Gradman, Julia E M Upton, Julie Wang, Kati Palosuo, Kirsi M Järvinen, Kirsten Beyer, Kunling Shen, Laura Polloni, Lianne Mandelbaum, Luciana Kase Tanno, Lucy A Bilaver, Marcus S Shaker, Margitta Worm, Maria Said, Mary Kelly, Mary Jane Marchisotto, Michael Makris, Mikaela Odemyr, Montserrat Fernandez-Rivas, Motohiro Ebisawa, Nandinee Patel, Pablo Rodríguez Del Río, Pakit Vichyanond, Paul Turner, Pete Smith, Pilar Morón Gaspar, R Sharon Chinthrajah, Rima Rachid, Roberta Bonaguro, Ruchi Gupta, Sabine Schnadt, Sakura Sato, Stefania Arasi, Stephanie Leonard, Sung Poblete, Susanne Halken, Thuy-My Le, Guillaume Pouessel, Tracey Dunn, Victoria Cardona, Torsten Zuberbier

Faculty, Staff and Students Publications

GA2LEN and EFA propose minimum specifications for all industrialised countries/regions to work towards to support students with food allergies in educational settings. We reviewed research and legislation and gained feedback from over 100 patient and professional groups. We built shared expectations around: 1. training all school staff about what food allergy is, the symptoms of allergic reactions, what to do in an emergency, and when and how to use and store devices that laypeople can use to administer adrenaline (epinephrine). 2. preventing allergic reactions by using clear labelling on school menus and prepacked and non‐prepacked foods and regular cleaning where …

Refinement Of A Published Gene-Physical Activity Interaction Impacting Hdl-Cholesterol: Role Of Sex And Lipoprotein Subfractions, Kenneth E Westerman, Tuomas O Kilpeläinen, Magdalena Sevilla-Gonzalez, Margery A Connelly, Alexis C Wood, Michael Y Tsai, Kent D Taylor, Stephen S Rich, Jerome I Rotter, James D Otvos, Amy R Bentley, Samia Mora, Hugues Aschard, D C Rao, Charles Gu, Daniel I Chasman, Alisa K Manning

Faculty, Staff and Students Publications

Large-scale gene-environment interaction (GxE) discovery efforts often involve analytical compromises for the sake of data harmonization and statistical power. Refinement of exposures, covariates, outcomes, and population subsets may be helpful to establish often-elusive replication and evaluate potential clinical utility. Here, we used additional datasets, an expanded set of statistical models, and interrogation of lipoprotein metabolism via nuclear magnetic resonance (NMR)-based lipoprotein subfractions to refine a previously discovered GxE modifying the relationship between physical activity (PA) and HDL-cholesterol (HDL-C). We explored this GxE in the Women’s Genome Health Study (WGHS; N=23,294; the strongest cohort-specific signal in the original meta-analysis), the UK …

The Influence Of Ultra-Widefield Fluorescein Angiography On The Diagnosis And Management Of Diabetic Retinopathy, Nicole K Scripsema, Tala Al-Khaled, Amy Song, Joelle A Hallak, Rawan Allozi, Aziz A Khanifar, Thanos D Papakostas, Christina Y Weng, Ronald C Gentile, J Peter Campbell, Jessica G Lee, Gennady Landa, Felix Y Chau, William F Mieler, Meenakashi Gupta, Amani A Fawzi, Judy E Kim, Jennifer I Lim, Robison Vernon Paul Chan

Faculty, Staff and Students Publications

Purpose: To study the influence of ultra-widefield fluorescein angiography (FA) on the diagnosis and management of diabetic retinopathy (DR).

Methods: Ten experts in DR completed an online survey in which they were asked to diagnose and manage DR cases using different imaging modalities. Experts independently reviewed 20 cases of DR and provided a diagnosis and management plan for each case, first based on ultra-widefield color-free and red-free images alone and again with the corresponding ultra-widefield FA images. Experts were polled on their diagnostic confidence, use of FA in clinical practice, and opinions on the value of ultra-widefield FA. Based on …

In Response To Comment On "Older And Better: A Narrative Review Of Successful Aging And Adaptation To Pain In Late Life", Emanuel Narcis Husu

Faculty, Staff and Students Publications

No abstract provided.

Primary Polydipsia In A Case Of Genetic Behavioral Variant Frontotemporal Dementia, Yesenia Cantu, Taryn White, Gabriela Austgen, Christine Rizk, Olaoluwa O Okusaga, Melissa B Jones

Faculty, Staff and Students Publications

No abstract provided.

Poststroke Impulsivity: A Narrative Review, Melissa B Jones, Dakota E Broadway, Malena Gimenez-Zapiola, Ricardo E Jorge

Faculty, Staff and Students Publications

In this narrative review, the authors examine the multidimensional nature and presentations of impulsivity after stroke. Impulsivity manifests as immediate or premature responses, impaired delayed gratification, perseverance despite punishment, and other displays of impaired emotional and behavioral regulation. The literature on the assessments, outcomes, and treatment of patients with these various manifestations after a cerebrovascular injury is reviewed. Findings from case reports indicate that poststroke impulsivity may manifest across neurobehavioral syndromes that are not well defined in the psychiatric nomenclature, such as alien hand syndrome and atypical impulse control disorders. Overall, impulse control disorders appear to be rare poststroke. Therapeutic …

Feasibility And Impact Of Knowledge-Based Automated Radiotherapy Treatment Planning In Low- And Middle-Income Countries, Awusi Kavuma, Solomon Kibudde, Yao Hao, Baozhou Sun

Faculty, Staff and Students Publications

Background and purpose: A high-quality treatment planning process is crucial in advanced radiotherapy techniques to ensure adequate dose to the target volume (TV) and sparing of organs at risk (OARs). This process often requires intensive labor, creating barriers for deployment in low- and middle-income countries (LMICs). We aimed to establish the feasibility of implementing knowledge-based auto-planning to facilitate clinical efficiency and increase patient throughput in an LMIC.

Materials and methods: We evaluated 60 randomly selected VMAT manual plans (VMPs), including 10 for each of the following sites: head and neck, oesophagus, breast, prostate, cervical, and rectal cancers. Using the same …

Cognitive Predictors Of Internalizing Symptoms In Clinically Anxious Youth, Dania Y Amarneh, Michael J Zvolensky, Eric A Storch, Andres G Viana

Faculty, Staff and Students Publications

Background: Internalizing disorders are the most common psychiatric disorders in youth and are associated with a host of deleterious outcomes (e.g., self-harm, substance use, interpersonal difficulties), highlighting the critical need for identifying risk factors that confer risk for these disorders. The present study investigated the unique and shared roles of two prominent cognitive biases-anxiety sensitivity and interpretation biases-as predictors of internalizing symptom severity in clinically anxious youth, above and beyond the effects of negative emotionality and after accounting for sociodemographic covariates.

Method: A diverse sample of clinically anxious youth (N = 105; Mage = 10.09 years, SD = 1.22; …

Treatment Fidelity And Outcome In Cbt For Youth With Autism: The Meya Fidelity Scale, Bryce D Mcleod, Jeffrey J Wood, Jennifer Cecilione Herbst, Danielle Dunn, Philip C Kendall, Eric A Storch, An Chuen Cho, Kashia A Rosenau

Faculty, Staff and Students Publications

Objective: Assessing treatment fidelity in effectiveness research is critical to interpreting study findings. This paper details the development and initial psychometric evaluation of the Modular Evidence-Based Practices for Youth with Autism Fidelity Scale (MEYA-FS) designed to support the assessment of cognitive-behavioral treatments for youth with autism in effectiveness research.

Method: Recorded treatment sessions (N = 338) were randomly selected from 77 youth (M age = 9.65 years, SD = 1.87; 50.67% White; 85.33% male) who received the Schema, Emotion, and Behavior-Focused Therapy for Children (SEBASTIEN) (n = 51) or Coping Cat (n = 24) program.

Results: …

Redesigning Home Reversion Products To Empower Retirement For Singapore's Public Flat Owners, Koon Shing Kwong, Jing Rong Goh, Jordan Jie Xin Lee, Ting Lin Collin Chua

Research Collection School Of Economics

This paper introduces an innovative sell-type home reversion product aimed at monetizing Singapore’s public flats, serving as a new alternative to the existing Singapore Lease Buyback Scheme (LBS). This new product not only retains the LBS’s guaranteed period of residence in the property along with life annuity incomes but also enhances the product features to meet specific homeowner needs, including the ability to age in place, flexibility in retaining part of the property, options for bequests, and guaranteed principal return. By incorporating these additional features, the new product seeks to stimulate greater demand for monetizing public flats among asset-rich but …

Guide To The Student Affairs Records, Thomas Burke, University Of San Diego. Student Affairs

University Records

The division of Student Affairs at the University of San Diego consists of a wide range of services and resources focused on student wellness and support. Student Affairs is broken down into five main categories: academic support, health and wellness, campus resources, get involved, and finding community. The materials in this collection include photographs from events, information guides, meeting and committee records, as well as student surveys conducted by the Higher Education Research Institute.

Finding Aids are tools used to aid research by describing the materials in a collection. University Records Finding Aids include historical and/or biographical information along with …

Collective Memory For The African Motherland In Interwar Black Chicago And The Limits Of The Environmental Justice Model, Colin Fisher

History: Faculty Scholarship

No abstract provided.

M.S. Engineering Management And Leadership - 2025 Capstone Chronicles, Adriana Garcia, Ser Andre Gonzalez, Matt Messina, Markus Egholm, Ersin Togmen, Ashley Isaacs, Anthony Byrd, Luai Qubain

Capstone Chronicles

No abstract provided.

Arts&Sciences Magazine Fall 2025, University Of San Diego

Arts & Sciences Magazine

02 | Messages from the Dean

03 | Rooted in Community

06 | Center Staging Connection

08 | A Look Inside the Honors Program

10 | Preparing Tomorrow's Health Leaders

20 | Awards and Honors

24 | Centerpiece

35 | Spotlights

42 | Off the Shelf

43 | Flashback

Stronger Shores: A Natural Capital Asset And Risk Register For The Northeast England Coastline Part Three: Application Of The Natural Capital Asset And Risk Register To Appraise Options And Assess Benefits Within Flood And Coastal Erosion Risk Management. A Report Has Been Compiled By Staff At The Marine Institute, School Of Biological And Marine Science, University Of Plymouth., Matthew Ashley, Helen Agosti, Tom Mullier, Tom Mullier, Riley Bibaud, Sian Rees

School of Biological and Marine Sciences

The Part Three report identifies the role and opportunity for application of the Natural Capital Asset and Risk Register evidence, provided in Reports Part One and Two, in appraisal of Nature-based Solutions (NbS) options within Flood and Coastal Erosion Risk Management (FCERM). Interventions applying NbS aim to increase extent and condition of specific habitat assets (ecosystem assets), therefore, considerable environmental benefits, as well as relevant cross-policy objectives are met when NbS are considered as an option. As such, the linked contribution to ecosystem services and associated benefits to people, and where possible economic value, needs to also be documented when …

An Initiative To Improve Sevoflurane Gas Flows Among Anesthesia Providers In An Academic Medical Center, Amy Dinicola

Graduate Theses, Dissertations, and Problem Reports (ETD)

Abstract

An Initiative to Improve Sevoflurane Gas Flows Among Anesthesia Providers in an

Academic Medical Center

Amy DiNicola

Background: While global warming has been introduced as the most significant public health threat of the 21st century, 10% of carbon emissions in the United States come from healthcare (Shoham et al., 2022). Sevoflurane is a volatile anesthetic gas that requires a carrier gas mixture of oxygen with air or nitrous oxide to reach a patient during anesthesia. The extra gas flow often exceeds physiologic needs, and the excess gets wasted into the atmosphere. Reducing the additional flow of carrier gas can …

Shaping The Future Of "Cardio-Kidney-Metabolic" Health: Insights From The Texas Heart Institute's 2024 Cardiometabolic Syndrome Conference, Arjun Raghuram, Keri Sprung, Stephanie Coulter, Joseph G Rogers

The Texas Heart Institute Journal

At the Texas Heart Institute's 2024 Cardiometabolic Syndrome Conference, held on August 23, 2024, experts from diverse academic fields spoke about novel initiatives for addressing the worsening projections for cardiometabolic syndrome. Four major areas in which innovation is ongoing were highlighted: technology, policy, population health, and lifestyle and behavioral modification. This article presents a brief contextualization, summary, and analysis of the novel initiatives being implemented in each of these 4 areas to address cardiometabolic syndrome. Despite alarming projections, cardiometabolic syndrome presents a unique opportunity for innovators to drive change through collaborative, multidisciplinary efforts.

Mody Calculator And Clinical Features Routinely Used To Distinguish Mody From Type 2 Diabetes In Adults Perform Poorly For Youth Clinically Diagnosed With Type 2 Diabetes, Raymond J Kreienkamp, Beverley M Shields, Toni I Pollin, Amy S Shah, Angela D Liese, Anna Bellatorre, Catherine Pihoker, Mustafa Tosur, Jose C Florez, Shylaja Srinivasan, Andrew T Hattersley, Miriam S Udler, Maria J Redondo

Children’s Nutrition Research Center Staff Publications

No abstract provided.

Identification, Mapping And Treatment Of The Invasive Rosa Multiflora Using Unmanned Aerial Systems And Machine Learning Models, Kylie Virginia Shaw

Graduate Theses, Dissertations, and Problem Reports (ETD)

Invasive species are introduced species that cause detrimental impacts to the native ecosystem or cause harm to human health. The work necessary for land managers to survey for and treat invasive species takes up limited time, labor, and financial resources. This study assesses how Unmanned Aerial Systems (UAS) and machine learning models can be used to make the identification, mapping, and treatment of invasive vegetation more efficient and effective. A UAS-mounted multispectral camera captured images of our target species, Rosa multiflora (multiflora rose), throughout its growing season in southwest Pennsylvania. A random forest machine learning model was trained on these …

Engineering Nanomaterials From Phase-Change Biological Materials Reacting With Carbon Dioxide, Qingyang Li

Graduate Theses, Dissertations, and Problem Reports (ETD)

The current global situation concerning CO2 emissions is increasingly alarming, with rising concentrations of CO2 significantly worsening climate change and global warming. Atmospheric CO2 levels are now at their highest in millions of years, driving a host of catastrophic effects, including but not limited to extreme weather events, rising sea levels, ocean acidification, disrupted ecosystems, deteriorating air quality, respiratory health issues, heat-related illnesses, threats to food and water security, and escalating social and geopolitical tensions. To keep global warming to no more than 1.5°C higher than that of pre-industry – as called for in the Paris Agreement – emissions need …

Framing The Moment, Shaping The Movement: News Narratives And Public Response To George Floyd’S Death, Madison B. Hall

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study investigates how national and local U.S. news outlets framed George Floyd, Black Lives Matter protesters, and the surrounding protests in the immediate aftermath of Floyd’s death. Through a qualitative content analysis of YouTube news broadcasts posted between May and June 2020, coupled with thematic analysis of popular comments that viewers posted in response, this research explores media narratives and public understanding of a pivotal moment of an ongoing racial justice movement. Drawing on framing theory and construal level theory, the study identifies a range of frames (i.e., pro-accountability, anti-accountability, raw perspective, neutral, episodic, riot) used by both local …

Improving Food Safety Practices Among Fsma-Exempt Small-Scale Produce Growers: A Manuscript-Based Dissertation On Risk, Adoption, And Practical Barriers, Jesica Marie Temple

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

Improving Food Safety Practices Among FSMA-Exempt Small-Scale Produce Growers: A Manuscript-Based Dissertation on Risk, Adoption, and Practical Barriers

Jesica Temple

Foodborne illness outbreaks associated with fresh produce continue to pose a public health risk in the United States. Although the Food Safety Modernization Act (FSMA) Produce Safety Rule (PSR) established science-based standards to prevent contamination, many small-scale farms are exempt from these requirements. Consequently, voluntary adoption of Good Agricultural Practices (GAP) varies widely across regions. Strategies to improve engagement among FSMA-exempt growers are key to advancing postharvest food safety and reducing contamination. This manuscript-based dissertation examined how knowledge, attitudes, …

Electro-Mechanical Behavior Of Core-Shell Carbon Grease-Silicone Fibers Fabricated Via Coaxial Direct Ink Writing, Fahrettin Kilic

Graduate Theses, Dissertations, and Problem Reports (ETD)

Highly stretchable strain sensors are essential components in soft electronics, enabling integration of sensing and signal transmission into deformable systems. This thesis explores the fabrication and characterization of coaxial core–shell fibers composed of a conductive carbon grease core and an elastomeric silicone shell. These fibers were produced using coaxial direct ink writing (DIW), a versatile additive manufacturing technique that allows continuous deposition of multi-material filaments. The goal was to achieve mechanically compliant yet electrically stable fibers capable of withstanding large deformations, suitable for applications in wearable electronics and soft robotics.
The printed fibers were systematically examined through mechanical tensile testing, …

Anxiety In College Students: The Impact Of An Educational Prevention Program, Jessica K. Pippin

DNP Projects

Anxiety affects millions of people in the United States. There is an increase in the numbers of college aged and young people with symptoms of anxiety. The signs and symptoms of anxiety can manifest itself in many ways. The purpose of this Doctor of Nursing practice (DNP) project was to determine if college aged students were aware of the symptoms, causes, and coping mechanisms related to anxiety. Online and in person educational sessions were offered on the campus of Mississippi University for Women (MUW). The participants participated in a pretest before the educational material was offered. The posttest was used …

Improving Social Determinants Of Health Screening Rates Among Healthcare Providers, Sarabeth Lee Clark

DNP Projects

Social Determinants of Health (SDOH) are non-medical factors that influence a patient's health outcomes. The WHO Commission on Social Determinants of Health has stated that improving SDOH is one of the most effective means of enhancing the well-being of all individuals and reducing disparities (Chelak et al., 2023). Implementing increased screening measures to identify deficits can positively impact patient outcomes by providing crucial resources that address patients' needs. This approach can significantly enhance the quality of healthcare services (Wark et al., 2021). The purpose of this Doctor of Nursing Practice quality improvement project was to evaluate self-reported screening rates for …

Impacting Nurse Practitioner Role Confidence Through A Mentorship Program, Mari Caitlyne Blaylock

DNP Projects

Mentorship is frequently overlooked as a key strategic focus in healthcare environments, yet it is essential for fostering a culture of mentorship. Structured mentoring initiatives offer significant benefits for both mentors and mentees. They enable nurses to build professional connections while enhancing their skills. It is essential for nurses to receive thorough mentorship that not only hones their professional abilities but also considers their emotional well-being. An increasing amount of research highlights the beneficial effects of mentorship on various outcomes, such as role confidence, job retention, and overall career satisfaction. Most health care systems lack a mentoring program specifically tailored …

“Ringleader Who Has No Power”: A Qualitative Study Of Parent Uncertainty During A Nicu Admission Unrelated To Prematurity, Erin Rholl, Steven R. Leuthner, Kathryn J. Malin, Joanne Lagatta, Krisjon R. Olson

College of Nursing Faculty Research and Publications

Background

Parents of preterm infants experience stress related to uncertainty which impacts parent health outcomes. Less is known about the experience of parents whose infants are admitted for reasons other than prematurity. In this study we sought to describe (1) the experience of parents whose infants are admitted to a level IV NICU for reasons unrelated to prematurity in relation to uncertainty and (2) the effect of social and structural determinants on parent experience with uncertainty.

Methods

This single center qualitative study utilized interviews, questionnaires, and chart review at 2 time points: 2 weeks after admission and 3 months after …

Evaluation Of A Quality Cpr Coach Simulation-Based Competency Training: From Learning Outcomes To Patient Outcomes, Katie L. Mcdermott, Kari L. Rajzer-Wakeham, Jennifer M. Andres, Christine A. Schindler

College of Nursing Faculty Research and Publications

Background

Variability in cardiopulmonary resuscitation (CPR) quality and skill decay result in suboptimal application of CPR, which impacts patient outcomes following an arrest. Quality CPR Coach is a supplementary code team role that provides real time, verbal feedback directly to chest compressors to cognitively offload the team leader and ensure high-quality, goal-directed CPR delivery.

Methods

Design, implementation, and evaluation of a simulation-based Quality CPR Coach competency curriculum. Multi-modal assessment and evaluation methods were used.

Results

Statistically significant increase in confidence, perceived ability to verbalize Coach responsibilities, and knowledge. Participants demonstrated accurate Coach role performance across progressively scaffolded simulated compression event …