Digital Commons Network^™

Legal Barriers To Maternal Healthcare Equity, Ashley Keith

Akron Law Faculty Publications

In examining contemporary maternal healthcare inequity in clinical care delivery, we must study the critical role played by the legal institutions in creating and perpetuating this problem. Comprehensive systems within the United States require legal advocacy and judicial enforcement to take shape and maintain their structural integrity. Healthcare in this country is no different. Legal institutions helped form and further, both intentionally and inadvertently, the racial disparities that we currently battle. Legal history plays an integral role in understanding why racial disparities in maternal mortality persist. One way for legal professionals to contribute to the ongoing efforts to achieve maternal …

Detecting Fake News Using Ai, Gustavo Lambert, Ignatio Varela

ICT

This project investigates how Artificial Intelligence (AI), specifically supervised machine learning techniques, can be applied to detect and classify fake news with high accuracy. The motivation stems from the widespread dissemination of misinformation on social media, where false narratives often spread faster than verified content. To address this issue, two distinct classification models were implemented and evaluated: one combining TF-IDF vectorization with Random Forest classifier, and another using TF-IDF with Logistic Regression. The TF-IDF technique was used to convert raw textual data into meaningful numerical features, capturing word frequency and relevance within the corpus. Both models were trained and tested …

The Use Of Deep Learning Solutions To Develop A Practice Tool To Support Lámh Language For Communication Partners, Gabriel Bueno Pimentel Borges

ICT

This study has proposed an alternative to promote the learning and enhancement of Lámh language for communication partners that support current users by creating a real time detection tool to recognise 20 chosen Lámh signs based on existing studies in the field. This implementation was carried out by generating primary data composed by MediaPipe landmark numpy arrays of 40 frames and 45 repetitions per sign. The Neural Networks were built using the Python library Keras and the applied SVM models were built with the library sklearn. The real time detection was carried out by integrating the mentioned elements with the …

Big Data Vs Big Law: The Impact Of Big Data And Machine Learning In Anonymising Or Synthesizing Data For Use Across Borders., Kenneth Darker

ICT

This research investigates the viability of anonymization and synthetic data generation in the area of big data so that the data could be shared across borders and exist outside the constraints of privacy laws. These privacy laws are growing around the world to help protect individual identity and prevent open sharing of private data. These privacy laws all provide guidance on how data may be shared and the strict conditions upon how that may occur. Two methods which are growing in popularity are anonymization of data, specifically k-Anonymity, l-Diversity and t-Closeness, and generating synthetic data from a real dataset leveraging …

Detecting Fake News Using Ai, Gustavo Lambert, Lucas Schultz

ICT

This is a document that presents a strategic analysis of the project “Detecting Fake News using AI”. Developed as part of the BSc (Hons) in Computing in IT at CCT College Dublin. The goal is to analyse the potential advantages, exploiting the viability and the impact of applying Artificial intelligence to check, verify and alert about misinformation found and to answer the question “How can Artificial Intelligence be leveraged to accurately detect and combat fake news while ensuring data privacy and compliance with regulations?” and “To what extent can AI-driven misinformation detection help reduce the spread of fake news on …

Work And Human Vocation In Catholic Social Teaching, Stefan M. Mcdaniel

Journal Articles

From the Article

This essay explores Catholic social teaching on work, focusing on how labor should enable humans to fulfill their vocation through experiences of dominion and communion. Drawing from papal encyclicals and theological anthropology, it examines how work becomes a means for humans to exercise their God-like faculties by intelligently shaping creation (dominion) and building rich relationships (communion). The essay argues that Catholic teaching offers distinctive contributions to contemporary workplace justice movements through its emphasis on two priorities: promoting worker-ownership and supporting family life. Worker-ownership, especially through cooperatives, enables labor to become an exercise of dominion, while family-centered policies …

Contract Or Prison, Sadie Blanchard

Journal Articles

Critics of the criminal enforcement system have condemned the expansion and privatization of electronic monitoring, criminal diversion, parole, and probation. But the astonishing perversion of contract involved in these new practices has gone unnoticed. Governments are turning to “offender-funded” programs that empower firms to contract with people who are suspected of or have been convicted of crimes— and whose alternative to agreeing to these contracts is prosecution or incarceration. Though incarceration-alternative (IA) contracting is sometimes framed as humane, historical and current context illuminates its coercive nature. IA contracting must be examined under classical contract theory and in light of the …

The Purpose Of The Preliminary Injunction, Samuel Bray

Journal Articles

This Article explores a reshaping of the preliminary injunction that is occurring in the federal courts. A preliminary injunction is designed to be a "hold in place" order, blocking actions by the parties that would undermine the efficacy of the court's remedial options. But the preliminary injunction is becoming a device for accelerating the merits decision. Instead of a four-factor test for preliminary relief, increasingly there is one factor: the merits. This Article critiques this transformation, and it argues that the preliminary injunction should be recentered on the protection of the court's remedial options.

Can The Sec Mandate Disclosures That Contain Both Financial And Social Information? The Case Of The Human Capital Management Disclosures, Patrick M. Corrigan

Journal Articles

Human capital contributes directly to the top and bottom line of corporate financial performance. However, theory predicts, and empirical studies suggest, that firms underinvest in human capital because of a classic public goods problem: since employees can always leave to work for another employer, firms cannot expect to bear all the fruits of investments they make in human capital. As human capital becomes more important in the modern service and technology economy, the ills of this public good problem are growing and the deficiencies of underinvestment becoming more apparent. This Article studies the potential role of human capital management disclosures. …

Going En Banc, Randy J. Kozel

Journal Articles

This Article examines the law of en banc review in the federal courts of appeals. It explores key doctrinal questions and advances a theory that maintains the primacy of three judge panels by focusing the en banc process on a specialized set of institutional tasks.

Litigating Climate Vulnerability: Climate Change Reparations In Global Jurisprudence And Empirical Results From The Notre Dame Climate Change Reparations Dataset, Diane A. Desierto, Anibal Perez-Linan, Faisal Yamil Meneses, Yuta Inada, Rachael Degaugh, Andrew Marciano

Journal Articles

From the article

The global surge in climate change litigation provokes inquiry into the nature, frequency, and scope of climate change reparations that international, regional, and national courts, as well as arbitral tribunals and other adjudicative bodies such as UN treaty body mechanisms, determine to be adequate, both on legal merits as well as intrinsic claims of justice, for the resolution of disputes brought by climate vulnerable persons, groups, and constituencies against States, multinational corporations, and other actors. Our findings from the Notre Dame Climate Change Reparations Dataset reveal a broad spectrum of pecuniary and non-pecuniary reparations being adjudicated in …

Originalism's Difference?, Sherif Girgis

Journal Articles

From the Aritcle

My topic is whether originalism makes any practical difference to constitutional reasoning and outcomes, relative to other methods of interpretation.

INTRODUCTION ............................................. 1945

I. JUSTICE SCALIA'S VISION OF CONTRASTS .................. 1949

II. THE BREAKDOWN OF CONTRASTS ........................... 1952

III. REMAINING CONTRASTS: REAL BUT ELUSIVE TO THEORY....................................................... 1961

IV. THE CHAMBERS ORIGINALISM DIFFERENCE .................. 1966

CONCLUSION: LOOKING AHEAD ................................ 1973

Voice-Activated Self-Monitoring Application (Vois): User Acceptance And Satisfaction In The Field, Hyunkyoung Oh, Li Yang, Tala Abu Zahra, Shiyu Tian, Min Sook Park, Jake Luo, Sheikh Iqbal Ahamed, Evelyn Chan, Jeffrey Whittle

Computer Science Faculty Research and Publications

This paper illustrates the processes and results of user acceptance and satisfaction tests for the voice-activated self-monitoring (VoiS) application conducted in the field. VoiS was designed and developed for individuals with diabetes (DM) and hypertension (HTN) to support their routine and convenient self-management using a smart speaker platform. VoiS is also accessible on users’ mobile devices to visualize user-generated data. A total of nine adults with DM and HTN participated and were asked to use the VoiS system at home for a week to identify its acceptability in real-world conditions. Participants completed phone interviews to report operational errors and a …

Digital Health Using Data Science, Padmapriya Velupillai Mekandan, Paramita Basak Upama, Masud Rabbani, Amity Ali, Sheikh Iqbal Ahamed

Computer Science Faculty Research and Publications

The digitization of healthcare has led to an unprecedented growth in health-related data, offering new opportunities to transform clinical decision-making, disease prediction, and patient engagement. However, extracting actionable insights from diverse data sources such as electronic health records, wearable devices, and mobile health apps requires a fusion of domain knowledge in healthcare and technical expertise in data science. This paper presents a structured, interdisciplinary framework for digital health that emphasizes practical strategies for data acquisition, preprocessing, feature engineering, machine learning, and ethical data use. The model promotes a holistic understanding of digital health challenges and opportunities, preparing future professionals to …

Secure Ios Mhealth Apps Development: An Ide-Embedded Framework For Hipaa-Aware Coding, Bajlur Rashid, Md Abdul Barek, Mostafizur Rahman, Sharmin Yeasmin, Hossain Shahriar, Sheikh Iqbal Ahamed

Computer Science Faculty Research and Publications

With the rapid growth of technology, accessing digital health records has become increasingly easier. Especially mobile health technology like mHealth apps help users to manage their health information, as well as store, share and access medical records and treatment information. Along with this huge advancement, mHealth apps are increasingly at risk of exposing protected health information (PHI) when security measures are not adequately implemented. The Health Insurance Portability and Accountability Act (HIPAA) ensures the secure handling of PHI, and mHealth applications are required to comply with its standards. But it is unfortunate to note that many mobile and mHealth app …

The Statewide Standard, 2025, Illinois State University

The Statewide Standard

Annual newsletter of the Illinois State University College of Education

Using Ai To Improve Study Skills, Lesley L. Rennis

Open Educational Resources

This module consists of three lesson plans designed to teach students to use AI tools responsibly and ethically to create outlines, refine research questions, and use APA referencing. By integrating AI into study practices, students enhance their organizational, analytical, and citation skills, while maintaining academic integrity. The lessons emphasize using AI as a tool to improve study skills so that more time can be spent on deep learning and critically thinking about class material.

Interventions To Improve Community Mobility In Autistic People: A Systematized Review, Sydney Maddox, Jada Ford, Heather Olson, Danielle Westmark, Stacy Smallfield, Molly Whitlow

Student Systematized Reviews: Occupational Therapy

Importance: Community mobility (CM) enables access to locations outside the home, allowing participation in work, leisure, and social environments. Autistic adults have reported less access to public transportation and driving than the general population (Wilson et al., 2021), impacting their community participation, life satisfaction, and likelihood of employment and further education (Egilson et al., 2016, Song et al., 2022, Wilson et al., 2021). Occupational therapists can support autistic people by providing interventions to increase CM.

Objective: To evaluate the effectiveness of interventions to improve CM in autistic people.

Methods: We collaborated with a medical librarian to conduct a systematic review …

Interventions To Improve Functional Use Of Hemiplegic Upper Extremity Post-Stroke: A Systematized Review, Brieana R. Dean, Sarah N. Wamsley, Halle Clary, Max W. Granstrom, Danielle Westmark, Bridgette Quinn, Stacey Smallfield, Molly Whitlow

Student Systematized Reviews: Occupational Therapy

Purpose: Stroke is a leading cause of long-term disability with upper limb hemiplegia, significantly limiting participation in daily life (Lee & Howe, 2024; Long et al., 2020). This systematized review was conducted to address interventions within the scope of OT used to improve functional use of hemiplegic UE for adults post-stroke. Design: A systematized review protocol was used with inclusion criteria of full-text, English-language articles addressing rehabilitation interventions for hemiplegic UEs post-stroke containing participants ranging from ages 18-85. A medical librarian at the McGoogan Health Sciences library conducted a search across multiple databases for articles meeting the criteria for the …

Safety Of Healthcare Workers In Acute Care During Patient Mobilization: A Systematized Review, Lina Al Azzawi, Peyton Collier, Delaney Ehlers, Ruby Kulovitz, Danielle M. Westmark, Stacy Smallfield, Molly Whitlow

Student Systematized Reviews: Occupational Therapy

Abstract synopsis

Evidence shows that low-tech aids and lifting equipment promote safe patient handling in acute care, with the most consistent support found for lifting equipment in reducing worker injuries. There was mixed evidence to support ergonomic training.

Abstract

The aim of this study was to identify interventions within the scope of occupational therapy that enhance safety during patient mobilization for healthcare workers in acute care settings.

This systematized review of safe patient handling interventions included peer-reviewed studies that target healthcare worker safety during patient mobilization in acute care settings.

A medical librarian performed searches in Medline, CINAHL, and Scopus. …

Benefit-Risk Assessment Of Rivaroxaban In Older Patients With Nonvalvular Atrial Fibrillation Or Venous Thromboembolism, Paul P. Dobesh, Albert A. Volkl, Ákos Ferenc Pap, C V Damaraju, Bennett Levitan, Zhong Yuan, Alpesh N. Amin

Journal Articles: Pharmacy Practice

BACKGROUND: Both bleeding and adverse ischemic events increase with age, compounding the benefit-risk balance of anticoagulants in older patients. We present analyses using benefit-risk methods to better understand the age-dependence of the benefit-risk profile of rivaroxaban in patients with nonvalvular atrial fibrillation (NVAF) or venous thromboembolism (VTE).

METHODS: Randomized controlled trial data from the ROCKET-AF (NVAF) and EINSTEIN DVT, EINSTEIN PE, EINSTEIN-Extension, and EINSTEIN CHOICE in (VTE) were used. For ROCKET-AF, benefits and risks were assessed with incidence rates for key thrombotic and bleeding endpoints and a net clinical benefit (NCB) measure. Cumulative incidences (estimated by the Kaplan-Meier method) were …

Author Biographical Notes

Midwest Social Sciences Journal

No abstract provided.

Cooperative Role Of Distinctive Tp53 And Pten Combined Loss In The Peripheral T Cell Lymphoma-Gata3 Molecular Subgroup, Waseem G. Lone, Jiayu Yu, Xuxiang Liu, Dylan T. Jochum, Alyssa Bouska, Kunal Shetty, Tyler Herek, Sunandini Sharma, Chengfeng Bi, Rauf Shah, Zaina W. Nasser, Catalina Amador, Aiza Arif, Abdul Rouf Mir, Yuping Li, Tayla B. Heavican-Foral, Jacob Robinson, R. Katherine Hyde, Mamiko Sakata-Yanagimoto, Satyanarayana Rachagani, Timothy W. Mckeithan, David W. Scott, Louis M. Staudt, Giorgio Inghirami, Andrew Feldman, Timothy Greiner, Julie M. Vose, Lisa Rimsza, Joseph Khoury, Wing C. Chan, Javeed Iqbal, Lymphoma/Leukemia Molecular Profiling Project (Llmpp)

Journal Articles: Oncology and Hematology

Peripheral T cell lymphoma (PTCL) is a heterogeneous group of postthymic T cell neoplasms, with ~40% classified as PTCL-not otherwise specified (PTCL-NOS). PTCL-GATA3, a molecularly defined subtype, associated with T helper 2 (T_H2)-like differentiation and poor prognosis, has frequent co-occurrence of TP53 loss/mutation and heterozygous PTEN loss. CD4+ T cell conditional mouse models with Trp53 mutation/deletion and Pten loss demonstrated mature T cell lymphomas (mTCLs) with T_H2-like transcriptomic and immunophenotypic profiles. Molecular studies revealed that codeletion of Trp53/Pten induced T cell receptor and Janus kinase-signal transducer and activator of transcription signaling, promoting T_H2 differentiation …

A Case Displaying The Importance Of Jak1 And Jak2 Gene Transcription In Antifungal Defense Against Coccidioidomycosis, Jennifer K. Priessnitz, Taylor Colore, Nelson Nicolasora

Department of Medicine Faculty Publications

This case report explores the consequences of ruxolitinib via inhibition janus kinase 1 (JAK1) and JAK2 pathways in the context of fungal defense in a patient diagnosed with pulmonary coccidioidomycosis during ruxolitinib therapy for polycythemia vera. The patient experienced a relapse of pulmonary coccidioidomycosis after antifungal treatment was discontinued while continuing ruxolitinib use. This case illustrates the heightened risk of discontinuing antifungal therapy in endemic regions, emphasizing the critical need for continued monitoring. Furthermore, this case underscores the vital role of the JAK1 and JAK2 signaling cascade, particularly the interferon-gamma (INF-γ)-JAK1 and JAK2-signal transducer and activator of transcription 1 (STAT) …

A Comprehensive Review On Utilizing Human Brain Organoids To Study Neuroinflammation In Neurological Disorders, Adrian Domene Rubio, Luke Hamilton, Mark Bausch, Mengmeng Jin, Ava Papetti, Peng Jiang, Sowmya V. Yelamanchili

Journal Articles: Anesthesiology

Most current information about neurological disorders and diseases is derived from direct patient and animal studies. However, patient studies in many cases do not allow replication of the early stages of the disease and, therefore, offer limited opportunities to understand disease progression. On the other hand, although the use of animal models allows us to study the mechanisms of the disease, they present significant limitations in developing drugs for humans. Recently, 3D-cultured in vitro models derived from human pluripotent stem cells have surfaced as a promising system. They offer the potential to connect findings from patient studies with those from …

Improving The Usability And Usage Of A Tracheostomy Order Set, Tony Satroplus, Teresa Y. Rodriguez, Jordon Flynn, Carly Garcia, Bennett J. Berning, Jayme Dowdall

Posters and Presentations: Otolaryngology

Educational Objectives: At the conclusion of this presentation, the participants should be able to (a) understand the benefits of simplifying EMR order-sets; (b) simplify a commonly used procedure or order set which includes identifying stakeholders who should contribute to the discussions; (c) identify and overcome barriers that would inhibit implementation and efficiency Objectives: Usability of electronic medical records has been linked to concerns for patient safety and provider wellness. One concern is that an order set’s “end user” may be inexperienced with the complexities associated with the tracheostomy patient continuum. The formation and utility of an intuitive workflow in the …

Proteomics Profiling Of Research Models For Studying Pancreatic Ductal Adenocarcinoma, Mathilde Resell, Hanne-Line Rabben, Animesh Sharma, Lars Hagen, Linh Hoang, Nan T. Skogaker, Anne Aarvik, Eirik Knudsen Bjåstad, Magnus K. Svensson, Manoj Amrutkar, Caroline S. Verbeke, Surinder K. Batra, Gunnar Qvigstad, Timothy C. Wang, Anil Rustgi, Duan Chen, Chun-Mei Zhao

Journal Articles: Biochemistry & Molecular Biology

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a five-year survival rate of 10-15% due to late-stage diagnosis and limited efficacy of existing treatments. This study utilized proteomics-based systems modelling to generate multimodal datasets from various research models, including PDAC cells, spheroids, organoids, and tissues derived from murine and human samples. Identical mass spectrometry-based proteomics was applied across the different models. The preparation and validation of the research models and the proteomics were described in detail. The assembly datasets we present here contribute to the data collection on PDAC, which will be useful for systems modelling, …

Metabolic And Proteomic Signatures Differentiate Inflammatory Phenotypes From Cancer And Predict Treatment Response In Patient Sera, Gabriel Cutshaw, Elena V. Demidova, Philip Czyzewicz, Elizabeth Quam, Nicole Lorang, Al Warith Al Siyabi, Surinder K. Batra, Sanjeevani Arora, Rizia Bardhan

Journal Articles: Biochemistry & Molecular Biology

Tumors shift their metabolic needs to enable uncontrolled proliferation. Therefore, metabolic assessment of cancer patient sera provides a significant opportunity to noninvasively monitor disease progression and enable mechanistic understanding of the pathways that lead to response. Here, we show Raman spectroscopy (RS), a highly sensitive and label-free analytical tool, is effective in metabolic profiling across diverse cancer types in patient sera from both pancreatic ductal adenocarcinoma (PDAC) and locally advanced rectal cancer (LARC). We also combine metabolic data with proteomic signatures to predict treatment response. Our data show RS peaks successfully differentiate PDAC patients from healthy controls. Peaks associated with …

Brightly Visualizing Pancreatic Cancer Margins In Orthotopic Mouse Models With An Anti-Ca19-9 Antibody Conjugated To A Near-Infrared Fluorophore, Kristin E. Cox, Javier Bravo, Sunidhi Jaiswal, Siamak Amirfakhri, Thinzar M. Lwin, Abhijit Aithal, Sumbal Talib, Lily J. Jih, Aylin Din Parast Saleh, Keita Kobayashi, Kavita Mallya, Maneesh Jain, Robert M. Hoffman, Aaron M. Mohs, Surinder K. Batra, Michael Bouvet

Journal Articles: Biochemistry & Molecular Biology

Background/Purpose: The only potentially curative procedure for pancreatic cancer is R0 resection, which is difficult to achieve due to poorly defined tumor margins. In the present study, we used an anti-CA19-9 antibody conjugated to a near-infrared fluorophore in orthotopic mouse models to target and visualize pancreatic cancer. Methods: Orthotopic models of the human pancreatic cancer cell lines SW1990 and BxPC3 were established by implanting tumor fragments into the pancreas of athymic nude mice. Anti-CA19-9 and control IgG were conjugated with IRDye800CW. Mice received 50 µg of CA19-9-IRDye800CW or IgG-IRDye800CW via tail-vein injection and were imaged after 72 h. MIA PaCa-2, …

Niclosamide Nanoparticles Enhance Pancreatic Cancer Sensitivity To Gemcitabine Via Hif-1Α Inhibition, Susheel Kumar Nethi, Venugopal Gunda, Nagabhishek Sirpu Natesh, Brianna M. White, Adam S. Mullis, Balaji Narasimhan, Surinder K. Batra, Surya K. Mallapragada, Satyanarayana Rachagani

Journal Articles: Biochemistry & Molecular Biology

Pancreatic cancer (PC) exhibits profound metabolic adaptations that support tumor progression, survival, and therapy resistance. Hypoxia-inducible factor-1α (HIF-1α) is a key regulator of these processes, promoting metabolic reprogramming and chemoresistance. Given that mitochondrial metabolites modulate HIF-1α stability, targeting mitochondrial metabolism offers a promising therapeutic strategy. Niclosamide (Nic), a clinically approved anthelmintic, disrupts mitochondrial function but is limited by poor bioavailability. To overcome this, we developed polyanhydride-based Nic nanoparticles (NicNps) to enhance bioavailability and efficacy. NicNps impaired mitochondrial function, suppressed metabolism, downregulated HIF-1α, and inhibited growth of PC cells and orthotopic gemcitabine (Gem)-resistant mouse tumor models. Notably, NicNps combined with Gem …