Digital Commons Network^™

The Experience Of Mothers Of Autistic Children With A Pathological Demand Avoidance Profile: An Interpretative Phenomenological Analysis, Sam Curtis, Elizabeth Izett

Research outputs 2022 to 2026

Purpose: Emergent research literature has identified emotional and behavioural challenges for autistic children with a pathological demand avoidance profile. However, understanding of their parents’ experience is limited. This study aimed to explore the experience of parents of autistic children with a pathological demand avoidance profile. Methods: Semi-structured interviews were completed with ten parents of autistic children with a pathological demand avoidance profile, aged between 5 and 11 years (M = 8.5, SD = 1.90). All participants were mothers, aged 33–50 years (M = 42, SD = 5.35). To explore what meaning participants gave to their lived experience, an interpretative phenomenological …

Interpretive Prediction Of Hyperuricemia And Gout Patients Via Machine Learning Analysis Of Human Gut Microbiome, Jia Wei Tang, Alfred Chin Yen Tay, Liang Wang

Research outputs 2022 to 2026

Hyperuricemia (HUA) and gout result from imbalances in uric acid metabolism and are closely associated with the gut microbiota. Advanced analytical methods facilitate the exploration of microbiota complexity. In this study, 16S rRNA sequencing data from stool samples of 233 patients were thoroughly collected. Machine learning (ML) and Shapley Additive exPlanations (SHAP) interpretability algorithms were applied to identify core taxa and predict the metabolic functions. The results revealed that the high-contribution core taxa identified by SHAP in each group, such as Oscillospiraceae_UCG-005 and Rhodococcus provided the basis for ML prediction. Among the five classification models, Random Forest (RF) achieved the …

Hamstring Strength And Architectural Properties Are Associated With Running Biomechanics, Nicholas Ripley, Christopher Bramah, Paul Comfort, John Mcmahon

Research outputs 2022 to 2026

Applied muscular strain and hamstring strain capacity have a joint interaction on hamstring strain injury (HSI) with modifiable risk factors frequently assessed. However, to date there is limited observations on the interaction between these factors. The purpose of the present study was to observe if spatiotemporal characteristics, running kinematics and muscle activation were related to modifiable risk factors of HSI. Twenty-two competitive team sport athletes (24.7 ± 4.3 years, 1.82 ± 0.07 m, 84.9 ± 8.5 kg) participated whereby the Bicep femoris long head (BFLH) fascicle length assessed via ultrasound and isokinetic eccentric hamstring strength was assessed. With running assessment …

Source-Specific Nitrate Intake And Incident Dementia In The Danish Diet, Cancer And Health Study, Catherine P. Bondonno, Pratik Pokharel, Dorit Wielandt Erichsen, Liezhou Zhong, Jörg Schullehner, Cecilie Kyrø, Kirsten Frederiksen, Peter Fjeldstad Hendriksen, Frederik Dalgaard, Lauren C. Blekkenhorst, Stephanie R. Rainey-Smith, Samantha L. Gardener, Torben Sigsgaard, Ole Raaschou-Nielsen, Anne Tjønneland, Jonathan M. Hodgson, Christina C. Dahm, Anja Olsen, Nicola P. Bondonno

Research outputs 2022 to 2026

Introduction: Dietary nitrate, through conversion to nitric oxide, which supports vascular and nervous system function, may lower dementia risk but may also form neurodegenerative N-nitrosamines, depending on the nitrate source. Methods: We investigated associations between source-specific nitrate and nitrite intake and incident and early-onset dementia (< 65 years) in 54,804 dementia-free participants from the Danish Diet, Cancer and Health Cohort Study over ∼27 years. Nitrate and nitrite intakes were derived from food frequency questionnaires and nitrate and nitrite databases. Results: Higher plant-sourced nitrate intake was non-linearly associated with lower rates of incident dementia (fifth vs first quintile hazard ratio 95% confidence interval: 0.90 [0.83, 0.98]), while increased risk was seen for higher intakes of animal-sourced, additive-permitted meat-sourced, and tap water-sourced nitrate. Similar associations were seen for source-specific nitrite intake and were more pronounced for early-onset dementia. No clear effect modification was observed. Discussion: These findings highlight the importance of nitrate source in dementia risk and warrant further investigation. Highlights: Plant nitrate is associated with a lower risk of incident and early-onset dementia. Animal and tap water nitrate are associated with an increased risk of dementia. Encouraging consumption of plant-based nitrate sources may lower risk of dementia.

Identifying Common Characteristics Among Female Serial Killers And The Role Of Early Childhood Abuse, Jill Marie Raichel

Walden Dissertations and Doctoral Studies

Approximately 17% of known serial killers in the United States are women, and often their crimes go undetected for years accruing a higher number of victims than their male counterparts. The purpose of this study was to identify common characteristics of female serial killers (FSKs). A multidisciplinary, holistic and developmental approach was used to guide the identification of common characteristics based on theories by Erik Erikson and Carol Gilligan as well as feminist theory. Case studies of 15 FSKs were randomly selected for participation from a list of over 100 known FSKs documented in the Radford Serial Killer database. Common …

A Cultural Staff Education Project To Improve Hypertension Management In African American Adults, Rosemary Nguatem Folefa Fonya

Walden Dissertations and Doctoral Studies

In this evidence-based educational project, I identified the gap in practice with the lack of nurses' knowledge in culturally tailored hypertension management among nurses caring for African American adults at a family nurse practitioner clinic. In this Doctor of Nursing Practice (DNP) project, I focused on a staff education initiative to improve nurses' knowledge to reduce disproportionately high rates of hypertension, complications, and mortality due to factors such as limited access to care, medication nonadherence, mistrust of providers, and improve on culturally competent interventions. The guiding practice-focused question was: Does educating nurses on hypertension in the African American population improve …

Neutrophil Gelatinase-Associated Lipocalin And Fibrinogen-To-Albumin Ratio Are Indicators Of Kidney Disease In Sickle Cell Disease Patients With Microalbuminuria: A Multicentre Case-Control Study In Ghana, Stephen Twumasi, Enoch Odame Anto, Christian Obirikorang, Richard Kobina Dadzie Ephraim, Benedict Sackey, Vivian Paintsil, Richard Owusu Ansah, Alfred Effah, Allwell Adofo Ayirebi, Angela Opoku, Godfred Yawson Scott, Leslie Osei, Joyce Duku, Emmanuel Asafo Adjei, Lilian Antwi Boateng

Research outputs 2022 to 2026

Background: Neutrophil gelatinase-associated lipocalin (NGAL) is present in secondary granules of neutrophils and it is a relatively newly recognized marker of kidney diseases. The fibrinogen-to-albumin ratio (FAR) is a marker of inflammation but its diagnostic value has not been determined in sickle cell disease patients with kidney diseases. This study investigated the diagnostic roles of serum neutrophil gelatinase-associated lipocalin (sNGAL) and FAR for kidney diseases in steady-state adult sickle cell disease (SCD) patients. Methods: This study employed a prospective case-control design and recruited 104 SCD participants and 80 non-SCD patients. Participants’ information was thoroughly documented using a structured questionnaire and …

Rising From Ashes: Generalized Federated Learning Via Dynamic Parameter Reset, Jiahao Wu, Ming Hu, Yanxin Yang, Xiaofei Xie, Zekai Chen, Chenyu Song, Mingsong Chen

Research Collection School Of Computing and Information Systems

Although Federated Learning (FL) is promising for privacy-preserving collaborative model training, it suffers from low inference performance due to heterogeneous client data. Due to heterogeneous data across clients, FL training easily learns client-specific overfitting features. Existing FL methods adopt coarsegrained averaging, which can easily cause the global model to get stuck in local optima, leading to poor generalization. Specifically, this paper presents a novel FL framework, FedPhoenix, to address this issue. It stochastically resets partial parameters in each round to destroy some features of the global model, guiding FL training to learn multiple generalized features for inference rather than specific …

De Novo Annotation Reveals Transcriptomic Complexity Across The Hexaploid Wheat Pan-Genome, Benjamen White, Thomas Lux, Rachel Rusholme-Pilcher, Angéla Juhász, Gemy Kaithakottil, Susan Duncan, James Simmonds, Hannah Rees, Jonathan Wright, Joshua Colmer, Sabrina Ward, Ryan Joynson, Benedict Coombes, Naomi Irish, Suzanne Henderson, Tom Barker, Helen Chapman, Leah Catchpole, Karim Gharbi, Utpal Bose, Moeko Okada, Hirokazu Handa, Shuhei Nasuda, Kentaro K. Shimizu, Heidrun Gundlach, Michelle L. Colgrave

Research outputs 2022 to 2026

Wheat is the most widely cultivated crop in the world, with over 215 million hectares grown annually. The 10+ Wheat Genomes Project recently sequenced and assembled to chromosome-level the genomes of nine wheat cultivars, uncovering genetic diversity and selection within the pan-genome of wheat. Here, we provide a wheat pan-transcriptome with de novo annotation and differential expression analysis for these wheat cultivars across multiple tissues. Using the de novo annotations we identify cultivar-specific genes and define the core and dispensable genomes. Expression analysis across cultivars and tissues reveals conservation in expression between a large core set of homeologous genes, in …

A Comparative Analysis Of Complete Streets And Multimodal Transport Approaches: Implications For Sustainable Urban Mobility In Lincoln, And Global Contexts, Oliva Richard Kilyenyi

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

Movement of people and goods in urban areas through different modes of transportation including walking, cycling, public transit and by autos is termed as urban mobility. Urban mobility presents significant environmental, social, and economic challenges for cities worldwide as they grapple with the impacts of conventional transportation systems, particularly in North America context where car-centric planning approaches has dominated urban developments since 1950s. Car-centric dominance is 80% in North American Metropolitan areas (Manaugh et al., 2015). The impacts of these conventional systems include greenhouse gas emission emissions contributing approximately 24% of global carbon dioxide (CO₂) emissions, air pollution …

A Low-Power Mixed-Signal Potentiostat System-On-Chip With Integrated Dual-Slope Adc, Seth Mcrobert

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

This thesis presents the design and characterization of a low-power mixed-signal potentiostat that was integrated with a 65 nm core in a SoC for low-power electrochemical sensing applications. The system integrates a low-noise transimpedance-based potentiostat front end with a 12-bit dual-slope analog-to-digital converter (ADC) for accurate current-to-digital conversion. The potentiostat core—comprising the control amplifier, current-mirror network, and transimpedance amplifier—consumes 38.2 µA from a 2.5 V supply (95.5 µW) and achieves an input-referred noise floor of 113 µVRMS over a 330 Hz bandwidth, while having an input current range from 1 nA to 20 µA and a noise-limited sensitivity of 56.4 …

Differential Microrna Profiling Of Blood L1cam And Bulk Extracellular Vesicles In Bipolar Disorder, Gabriel R Fries, Salahudeen Mirza, Jun Wang, Camila N C Lima, Wei Zhang, Marcela Carbajal Tamez, Giselli Scaini, Jair C Soares, Joao Quevedo

Faculty, Staff and Student Publications

Objective: This preliminary study aimed to identify microRNA (miRNA) signatures associated with bipolar disorder (BD) by profiling blood-derived extracellular vesicles (EVs) of both putative neuronal origin and from all sources.

Method: In two parallel studies of individuals with BD and controls (CON), we characterized miRNA expression profiles of blood EVs selected for L1CAM, a putative marker of neuronal origin (n = 20 BD/20 CON), as well as bulk EVs (n = 21 BD/20 CON). For each study, analyses identified miRNAs differentially expressed between groups, followed by functional interrogation and testing for associations with clinical features.

Results: Results of …

Chapter 5: The Chemical Calculator, Garon C. Smith

G. Wiz’s Book of Spells

The Chemical Calculator combines invisible ink with a sophisticated math trick. The audience is poled for digits to use in either a 2-digit or 3-digit set of calculations. Once the digits have been obtained, a difference is calculated between the original set of digits and the same digits in reverse order. That answer is added to a reversed version of itself. The chemical calculator is a solution in a spray bottle. When the spray bottle has had a chance to examine the problem, it contents are sprayed at the bottom of the sheet. The correct answer appears. A bit of …

Bridging Conservation And Planning: State Wildlife Action Plans Analyzed Using Wildlife Value Orientation, Ciara Nelson-Forcade

Community and Regional Planning Program: Theses

Wildlife conservation in the United States has transitioned from managing resources for human use to prioritizing ecosystem preservation and species protection. However, the ways in which conservation values and attitudes are reflected in state-level policy documents remain insufficiently examined. This thesis investigates how Wildlife Value Orientations (WVO) are expressed within State Wildlife Action Plans (SWAPs). Using a qualitative content analysis and flexible coding approach, fifteen SWAPs representing all eight U.S. Fish and Wildlife Service regions were analyzed to identify conservation themes, value orientations, and structural characteristics such as plan length, departmental budgets, and political context. Findings reveal that most plans …

Transportation Practitioners' Reflections On Addressing Transportation Barriers For Vulnerable Populations In Nebraska, Aysan Esmaely

Community and Regional Planning Program: Theses

This study examines transportation planning practices and challenges in Nebraska, with particular attention to how planners and agencies address the needs of vulnerable populations. Using a qualitative approach, thirty-five transportation planners, practitioners, and service providers were interviewed. Participants were selected based on their professional in transportation planning and service delivery. The study explores what institutional and funding barriers planners and practitioners face, and what strategies they consider most effective for improving access and inclusion. Findings reveal that limited funding, fragmented authority, and the absence of a coordinated regional planning framework significantly constrain transportation development across Nebraska. While metropolitan areas such …

Evaluating The Preparedness Of Local Zoning Regulations For Flood Risk Reduction In The Most Affected Local Jurisdictions In Nebraska, Md Asaduzzaman Noor

Community and Regional Planning Program: Theses

Flooding has profound social, economic, and environmental impacts on local communities, and zoning plays a critical role in mitigating these risks. The 2019 Nebraska floods, among the most severe in the state’s history, highlighted the urgent need to strengthen local preparedness and mitigation strategies. This study assesses the extent to which local zoning regulations in Nebraska’s most affected jurisdiction, including rural areas, address flood risk reduction. A systematic review of 117 zoning ordinances from counties, cities, towns, and villages, we applied a structured analytical framework encompassing regulatory and permitting policies, voluntary and incentive-based measures, and nature-based solutions. The results show …

Bridging Conservation And Disaster Recovery: A Dual Study On Wetland Program Plans Evaluation And Midwest Post Disaster Recovery Assessment, Rao Nargis Jahan

Community and Regional Planning Program: Theses

Wetlands provide essential ecological, social, and economic benefits for our society. In the United States, states and tribes play crucial roles in wetland protection, restoration, and management. However, no research has systematically measured state-level wetland planning efforts towards national conservation goals. This study is the first to comprehensively evaluate how state-level Wetland Program Plans (WPPs) align with national missions, particularly the "no-net-loss" of wetlands goal. Our research assesses the EPA-approved state-level WPPs from 42 out of 50 states in the United States during the period from 2015 to 2024. Using a protocol of 30 indicators across five categories, this study …

Flood Resilience Through Working-Land Conservation: Assessment Of Wetland Inundation Dynamics Across Wrp, Wma, Wpa, Padus And Crp Lands In Nebraska (2018–2024), Pranjay Joshi

Community and Regional Planning Program: Theses

This study first confirms whether Nebraska’s wetlands are still functioning hydrologically in ways that reduce flood impacts. Wetlands are known to lessen flood damage by storing water, slowing runoff, and moderating peak flows, but these benefits depend on the wetlands’ ability to maintain inundation and saturation through time. Many wetlands across the state have undergone drainage, hydrologic alteration, or isolation from surrounding watersheds, raising uncertainty about their present-day functioning. Using seven years of Sentinel-2 imagery processed in Google Earth Engine, this research establishes a clear, long-term record of inundation patterns across thousands of wetland parcels. This analysis verifies which wetlands …

Improving Patient Access To Providers By Optimizing Message Center Workflow, Serena Valino

Walden Dissertations and Doctoral Studies

This project was an evaluation of a quality improvement initiative that addressed the practice problem of having large volumes of unanswered messages within the patient portal. To increase patient access to the healthcare provider, a literature search was conducted using the practice-focused question: Can standardization of patient portals improve the message turnaround time? In January 2024, a scoping review of nursing message center pools determined 79 pools lacked standardized names and established workflows for 37 ambulatory clinics. Pool names were identified for each clinic and listed using an Excel spreadsheet. Clinic pool members were isolated, and it was determined by …

Executive Summary: Executive Leadership System Improvement Workplace Violence, Mercedes Ivette Tejada

Walden Dissertations and Doctoral Studies

Introduction This Doctor of Nursing Practice (DNP) Executive Leadership Project is focused on the reduction of workplace violence in a critical access hospital using an organized prevention program. Workplace violence in nursing is increasing, exposing the health of staff, patient safety, and quality of care in critical access hospitals. The question of the DNP project is: In nurses (P) in small critical access hospitals, how does implementing a structured workplace violence prevention program (I) compared to having no formal violence prevention strategy (C) impact the occurrence of workplace aggression and perceptions of safety among staff (O)? This practicum project used …

Relationships Of Upper Respiratory Tract Infections And Holistic Diets And Lifestyles In Northeast China, Hongmei Wang, Khui Hung Lee, Shaoxiao Qin, Kan Yu, Shaoying Hou, Kaihong Tang, Jiabao Liu, Yingyu Jin, Zhuo Shang, Deyu Dai

Research outputs 2022 to 2026

Background: Upper respiratory tract infections (URTIs) are prevalent public health issues worldwide. Their prevention is challenging, and they pose a significant economic burden due to their susceptibility to secondary infections and lack of effective treatments. This study investigates the relationship between URTIs and the holistic diets and lifestyles of residents in Northeast China. Methods: A cross-sectional study was conducted using data from 4058 participants aged 12 to 70 who participated in the Internet-based dietary questionnaire for Chinese (IDQC), collected between 2012 and 2019. Statistical analyses were performed with SPSS 20.0 software, employing chi-square tests for categorical data and Kruskal-Wallis tests …

As Effective As You Perceive It: The Relationship Between Chatgpt’S Perceived Effectiveness And Mental Health Stigma, Scott N. Hannah, Deirdre Drake, Christopher D. Huntley, Joanne M. Dickson

Research outputs 2022 to 2026

Individuals are increasingly using artificial intelligence chatbots, such as ChatGPT, to seek conversational support for their personal mental health difficulties. Heightened concerns about mental health stigma may make anonymous, on-demand chatbot interactions more appealing for some than traditional face-to-face support. This study examined if using ChatGPT-4 for personal mental health difficulties is associated with two distinct forms of stigma, anticipated stigma and self-stigma. Our main aim was to investigate if the perceived effectiveness of ChatGPT use for mental health issues mediates the relationship between ChatGPT usage and anticipated stigma and self-stigma. The sample comprised 73 participants, mostly undergraduate psychology students. …

Animals, Children's Health

Book Recommendations

Book recommendation list from the digital library collection focused on the topic of animals.

...Of Cabbages And Kings, Fall 2025, Emeriti Society, University Of The Pacific

Emeriti Newsletter: "...Of Cabbages and Kings"

"...Of Cabbages and Kings" is the newsletter of the University of the Pacific Emeriti Society. Read more about the Emeriti Society of Pacific by clicking here.

Anti-Inflammatory Effects In Apio Tuber, Jeehye Seo, Oluwatobi Amusat, Yu-Yun Wang, Annegret Jannasch, Sun-Ok Lee

Food Science Undergraduate Honors Theses

Inflammation is a crucial component of the body’s defense system but can lead to chronic diseases when uncontrolled. Diets rich in anti-inflammatory compounds are recognized as an effective strategy for mitigating chronic inflammation. This study investigated the anti-inflammatory potential of Apio (Arracacia xanthorrhiza), an underutilized Andean tuber. The goal of this study was to explore the health-promoting properties of Apio tuber, which could expand its commercial value to support local farmers and contribute to more sustainable agricultural practices.

Phenolic compounds were extracted from white (WAT) and yellow Apio tuber (YAT), and Total Phenolic Content (TPC) and antioxidant capacity …

The Fate Of Meaning In An Age Of Machines: A Nietzschean Warning On Artificial Intelligence, Graham Johnston

SPARK Symposium Presentations

Artificial intelligence is quickly taking precedent in lives all over the world. It has emerged as one of the most controversial inventions of the 21st century, and represents a larger digital shift that is being taken among first world society. As our lives shift into unprecedented digitized territory, new technology brings more questions than answers, but there seems to be no slowing down despite patches of uncertainty. AI brings new forms of innovation to the table that drastically change the way humans interact with productivity as a whole. When these factors are observed from a philosophical lens, patterns arise that …

A Faith-Based Approach To Mental Health Challenges, Patrick Leblanc

Doctor of Ministry Theses and Dissertations

ABSTRACT

This project sheds light on mental health issues within the Black community and the need for faith communities to intentionally address mental health issues in communities of color. Black men are oppressed by an interplay of cultural, historical, societal, and economic factors that impact their well-being. Racial discrimination and oppression are non-medical drivers exacerbating mental health disorders among Black men. The influences of culture and faith fabricate barriers to help-seeking behavior, and mistaken perceptions of masculinity cause many men to suffer in silence. To begin erasing derogatory perceptions of mental health disorders, faith communities need to increase mental health …

The Spiritual Care Of Hospice Patients With Cognitive Deficits, Shane Sullivan

Doctor of Ministry Theses and Dissertations

ABSTRACT How can a hospice chaplain know whether their presence and ministry make a meaningful difference when visiting patients with dementia or other serious cognitive impairments? This project thesis seeks to answer that question conclusively. The theological foundation of this project centers on the doctrine of the imago Dei—the image of God—as it relates to individuals who are dying with cognitive deficits. Specifically, it explores how a person who is helpless and near death continues to reflect the image of God. The project intervention described here is the creation of a specialized training guide for hospice chaplains at Bridge Hospice …

Student Perceptions Of The Impact Of Faculty Race And Gender On Their Sense Of Connectedness, Engagement, And Persistence, Sherrie Y. Fuller

Dissertations

This quantitative study examined how faculty demographic characteristics, specifically race and gender, influence undergraduate students’ perceptions of connectedness, engagement, and persistence at a public Midwestern university. Guided by Tinto’s Model of Student Integration (1975, 1993, 2012), the research explored whether perceived alignment between student and faculty identities contributes to students’ sense of belonging and motivation to persist toward degree completion. Data were collected from 100 undergraduate participants representing diverse racial, gender, and academic backgrounds. Participants completed a researcher-developed survey instrument utilizing a four-point Likert scale to measure connectedness, engagement, and persistence.

Introduction And Letter To Firas And Ali, Joanna Zabielska

International Dialogue

In this deeply personal and politically charged epistolary essay, Joanna Zabielska reflects on the intersecting forms of erasure occurring within European cultural institutions and at the continent’s militarized borders. Framed as a letter to two men—Firas and Ali—whom the author met during the humanitarian crisis at the Polish-Belarusian border, the piece recounts their experiences of pushbacks, violence, detention, and survival, contextualizing their stories within a broader critique of European migration regimes. Zabielska juxtaposes this with her account of institutional censorship in Austria, where the names of the two men were removed from her VR installation Über das Neue at Belvedere …