Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2025

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 5071 - 5100 of 76170

Full-Text Articles in Entire DC Network

Overruled Cases As A Tool For Inculcating Legal Realism, Michael C. Dorf Dec 2025

Overruled Cases As A Tool For Inculcating Legal Realism, Michael C. Dorf

William & Mary Bill of Rights Journal

The changes wrought by Dobbs and Students for Fair Admissions v. President and Fellows of Harvard College (SFFA) are hardly the only examples of momentous changes to constitutional law in the last few years. Doctrines involving the religion clauses of the First Amendment, the Second Amendment, the scope of the president’s removal power, and much more have been changing rapidly since Amy Coney Barrett replaced Ruth Bader Ginsburg in the fall of 2020, thereby solidifying a conservative supermajority on the Supreme Court. I imagine that the strengthening of the major questions doctrine, the overruling of Chevron deference to federal administrative …


Show And Tell: Writing Constitutional Law Casebooks When The Law Doesn't Matter, William D. Araiza Dec 2025

Show And Tell: Writing Constitutional Law Casebooks When The Law Doesn't Matter, William D. Araiza

William & Mary Bill of Rights Journal

Writing a constitutional law casebook today presents significant challenges. One reason among several stands out: law matters less—indeed, sometimes very little—to those charged with interpreting our constitutional law and implementing our constitutional system.

This Essay examines this challenge and explains how my contribution to the constitutional casebook genre attempts to answer it. It argues that the current moment requires instructors, and the books they use, to “show”—that is, to demonstrate to their students both the handiwork of those interpreters and implementers and alternative pathways. Sometimes, however, practical considerations preclude such showing. In those situations, “telling” may be required. But regardless …


Intellectual Integrity, Collaboration, And The Market, Mark Tushnet Dec 2025

Intellectual Integrity, Collaboration, And The Market, Mark Tushnet

William & Mary Bill of Rights Journal

My reflections are those of someone who co-edited/co-authored two casebooks that were commercially and intellectually successful and one that was intellectually but not commercially successful. I start with the assumption that people decide to do a casebook because they find that existing materials don’t do some things they think ought to be done in the course (and do some things that aren’t really necessary for teaching purposes). That is, doing a casebook is at the outset an intellectual project.

Executing that project runs up against some constraints almost immediately. A simple one is that you might well think that you …


What Belongs In A Constitutional Law Casebook?, Ernest A. Young Dec 2025

What Belongs In A Constitutional Law Casebook?, Ernest A. Young

William & Mary Bill of Rights Journal

This Essay argues that constitutional law cannot (and should not) be an autonomous subject within the legal curriculum. This argument echoes a long-standing debate about whether law itself is an autonomous scholarly discipline. The answer to that question is surely, as Allan Farnsworth put it, “sometimes YES and sometimes NO.” But this Essay does not focus on law’s autonomy from other disciplines, such as political science, psychology, or economics. Rather, I consider the extent to which constitutional law should overlap with other legal subjects, such as legal history, administrative law, or statutory interpretation. My conclusion is that, at least in …


South Dakota Newcomers Survey Report, Weiwei Zhang, Kara Harders Dec 2025

South Dakota Newcomers Survey Report, Weiwei Zhang, Kara Harders

Center for Rural Vitality and Community Well-being Project Reports

Project Overview:
 While more populous states typically attract larger numerical influxes from other states and abroad, South Dakota has nevertheless experienced growth in immigrants, both from other states and internationally. In 2024, South Dakota State University Extension launched a state-wide Newcomer Survey to gain a better understanding of the newcomer population. Following prior work in Minnesota and Montana, the South Dakota Newcomers Survey was developed to collect data about the motivations that drive people to move to South Dakota, what they enjoy once moved, what they want more or less of, and ultimately what makes them want to, or not …


Asking Nicely: Americans’ Perception Of Jordanian Arabic Speakers’ Politeness When Making Requests In English, David Henen Dec 2025

Asking Nicely: Americans’ Perception Of Jordanian Arabic Speakers’ Politeness When Making Requests In English, David Henen

Electronic Theses and Dissertations

This study examines how Arabic-speaking Jordanian male graduate students at an American university in Mississippi employ request directness strategies and modifications as polite devices in oral English, and how American native speakers perceive these requests. Drawing on Brown and Levinson’s (1987) Politeness Theory and the Cross-Cultural Speech Act Realization Project taxonomy (Blum-Kulka et al., 1989a, 1989b), this study employed a mixed-methods design to examine request production and perception. Data were collected from six American English native speakers from Mississippi and six Arabic-speaking Jordanian international students, all at the same university, through six discourse completion tasks, six role-plays, and semi-structured interviews. …


The Nature Of Nasal Discharge In Chronic Rhinosinusitis: A Systematic Review And Meta-Analysis Using Patient-Reported Outcomes, Ethan M. Kallenberger, Asher T. Ripp, Shaun A. Nguyen, Erin Briggs, Alexander N. Duffy, Isabella V. Schafer, Jess C. Mace, Timothy L. Smith, Zachary M. Soler, Rodney J. Schlosser Dec 2025

The Nature Of Nasal Discharge In Chronic Rhinosinusitis: A Systematic Review And Meta-Analysis Using Patient-Reported Outcomes, Ethan M. Kallenberger, Asher T. Ripp, Shaun A. Nguyen, Erin Briggs, Alexander N. Duffy, Isabella V. Schafer, Jess C. Mace, Timothy L. Smith, Zachary M. Soler, Rodney J. Schlosser

SKMC Student Presentations and Publications

OBJECTIVE: The objective of this study is to answer the question "What is the most common and severe type of nasal discharge in patients with chronic rhinosinusitis (CRS) at baseline as measured by patient-reported outcomes?".

METHODOLOGY: Two independent reviewers evaluated studies for inclusion, extracted data from included studies, and performed critical appraisal of studies. Data on the four Sino-Nasal Outcome Test 22 (SNOT22) discharge questions, demographic, and comorbidity data was collected. Meta-analysis of single means and proportions was performed for demographic, comorbidity, severity, and prevalence data.

RESULTS: A total of 53 studies (n = 6584) were included for analysis. Postnasal …


Exploring The Relationship Between Exercise, Social Support, And Mental Health, Emma Anderson Dec 2025

Exploring The Relationship Between Exercise, Social Support, And Mental Health, Emma Anderson

Honors Theses

This study explored the relationship between exercise, social support, and mental health in college students. Mental health issues such as depression, anxiety, and stress are prevalent among college students. The two components that are experimented with for their potential in decreasing the effects of negative mental health are exercise and social support. This project executed a cross-sectional design by surveying three groups of college students: cycle class participants, independent exercisers, and non-active students. The recruitment process for the three groups of participants were key in measuring the physical activity levels. The participants were individually asked if they completed a specific …


Relationships Among Institutional Betrayal, Adverse Healthcare Experiences, And College Student Health, Saba Mustafa Dec 2025

Relationships Among Institutional Betrayal, Adverse Healthcare Experiences, And College Student Health, Saba Mustafa

Honors Theses

Institutional betrayal is defined as the trauma experienced by an individual who feels that their trust in the ability of an institution to keep the individual safe is broken. Healthcare-related institutional betrayal has primarily been explored among working adults, individuals with chronic conditions, and individuals from racially diverse backgrounds. However, healthcare-related institutional betrayal has seldom been explored in college student samples, who may have different healthcare needs compared to other patient populations. The present study explored college students’ experiences with institutional betrayal due to negative healthcare experiences. Survey data were gathered from 157 college students. Measures included healthcare provider trust, …


Hand Injuries In Boulderers Across Various Settings, Experience And Skill Levels., Cole E. Olinger Dec 2025

Hand Injuries In Boulderers Across Various Settings, Experience And Skill Levels., Cole E. Olinger

Honors Theses

Survey-based research was performed to identify risk factors and prevention tactics for finger injuries in boulderers. An IRB-approved survey was distributed and taken by 228 respondents, whose data was analyzed. Risk factors for finger injury were found to include years of experience and skill level. Results indicated stronger, more experienced boulderers were more likely to report history of finger injury than weaker, less experienced boulderers. Findings suggest boulderers may avoid injury by manipulating their grip type in specific ways.


Youth Program Fy2025 Evaluation Report, Madhawa Palihapitiya, Karina Zeferino Dec 2025

Youth Program Fy2025 Evaluation Report, Madhawa Palihapitiya, Karina Zeferino

Massachusetts Office of Public Collaboration Publications

A School Climate Needs Assessment completed by 57 administrators evaluated both overall school climate and the key components that contribute to it. Administrators revealed low satisfaction with overall school climate (25%) and with students’ SEL skills (19%), and most considered these areas important to improve (77% and 79%) and expressed a desire for support (60% and 53%). Similar patterns emerged for academic performance (28% satisfied; 86% considered improvement important; 44% desired support), disciplinary actions (19%; 54%; 49%), and conflict levels—student-student (21%; 79%; 60%) and student-teacher (26%; 49%; 47%). Across these domains, a substantial proportion of respondents—often …


Relations Between Ethnic-Racial Identity Statuses And Critical Consciousness Among Latine Adolescents, Kristia A. Wantchekon, Esther Burson, Olga Kornienko, Norma J. Perez-­ Brena, Maciel M. Hernández, M. Dalal Safa, Thao Ha Dec 2025

Relations Between Ethnic-Racial Identity Statuses And Critical Consciousness Among Latine Adolescents, Kristia A. Wantchekon, Esther Burson, Olga Kornienko, Norma J. Perez-­ Brena, Maciel M. Hernández, M. Dalal Safa, Thao Ha

Psychology: Faculty Publications

Ethnic-­racial identity (ERI) development reflects the processes through which adolescents learn about their ethnic-­ racial background (i.e., exploration) and develop clarity about what it means to them (i.e., resolution). Research on ERI has been critiqued for not examining connections between ERI and broader social beliefs, such as critical consciousness (i.e., individuals' level of reflection about social oppression, motivation to take action against it, and the extent to which they take such action). When examining connections to ERI, research underscores the importance of considering individuals' patterns of exploration and resolution in tandem (i.e., ERI status) rather than analyzing them in isolation. …


Investigating Nutrient Management & The Impacts Of Nitrogen On Blackberries Across Arkansas And The Southeast, Amanda Michelle Lay-Walters Dec 2025

Investigating Nutrient Management & The Impacts Of Nitrogen On Blackberries Across Arkansas And The Southeast, Amanda Michelle Lay-Walters

Graduate Theses and Dissertations

Current blackberry (Rubus subgenus Rubus) research on nutrient needs, monitoring practices, and dynamics in the United States has primarily been conducted on cultivars popularly grown in the Pacific Northwest. Thus, regional research is required to understand the needs of blackberry cultivars grown in the southeastern U.S., with southeastern U.S. production practices. In 2022 and 2023, 12 cultivars of blackberry, across seven states, were leaf tissue sampled across multiple phenological stages for nutrient analysis. In Clarksville, AR from 2022 to 2024, six rates of N were applied to established ‘Ouachita’ blackberry plants. During the trial, plant yield, post-harvest fruit quality, fruit …


Preventing, Delaying, And Managing Chronic Disease, Michele Dinman, Logan Fox Dec 2025

Preventing, Delaying, And Managing Chronic Disease, Michele Dinman, Logan Fox

Harvey A. Friedman Center for Aging

We are living longer. Today, men and women who reach age 65 will live another 17 to 20 years, on average. As the human body ages, normal biological changes increase vulnerability to illness, and the risk of developing disease increases. At the same time, advances in public health, medicine, and health care have reduced deaths from acute conditions, like infection and accidents, and have increased our chances of living longer into the human life span. Thus, we now have greater chances of developing one or more chronic diseases. Most (75%) adults in the U.S. live with at least one chronic …


Being A Caregiver For A Friend Or Family Member, Nancy Morrow-Howell, Michele Dinman Dec 2025

Being A Caregiver For A Friend Or Family Member, Nancy Morrow-Howell, Michele Dinman

Harvey A. Friedman Center for Aging

Informal caregivers give assistance to family and friends who have functional limitations that challenge self-care. Most often, caregivers assist younger adults living with a disability and older people with age- associated chronic conditions. Family caregivers are the backbone of our long-term care system in this country, delivering 80% of care. Caregiving is increasing as people live longer with more chronic conditions. Indeed, caregiving is the new norm in our older society. As Roselyn Carter said: "There are only four kinds of people in the world. Those who have been caregivers, those who are currently caregivers, those who will be caregivers, …


Lifelong Civic Engagement, Logan Fox, Emma Ward, Cal J. Halvorsen Dec 2025

Lifelong Civic Engagement, Logan Fox, Emma Ward, Cal J. Halvorsen

Harvey A. Friedman Center for Aging

Civic engagement can be broadly defined as the practice of service (volunteering or informal helping), advocacy, and political participation (voting). Older adults are a large and growing population that frequently engages in these civic activities.

In 2022, the Bureau of Labor Statistics reported that approximately one quarter of the 11 million daily volunteers in the U.S. were age 65 and older. Between 2018 and 2021, there was a 10% increase in volunteer hours filled by individuals over age 65. Research shows this trend will be mutually beneficial, improving the quality of life for older adults who are, in turn, positively …


Enabling Scalable Camera-Based Streamflow Monitoring With Serverless Cloud Computing, Sajan Neupane Dec 2025

Enabling Scalable Camera-Based Streamflow Monitoring With Serverless Cloud Computing, Sajan Neupane

All Graduate Theses and Dissertations, Fall 2023 to Present

This thesis introduces a modern and automated method for monitoring rivers and streams using cameras and cloud-based software tools. Traditional monitoring methods often rely on sensors placed directly in the water, which can be expensive, hard to install, and difficult to maintain, especially in remote or rough terrain. In contrast, this approach uses cameras to observe water flow from a distance, offering a safer and more cost-effective alternative. However, camera systems come with their own challenges, such as collecting large amounts of image data, transferring it reliably from the field, and analyzing it quickly enough to be useful. This research …


Social Media Mining For Extracting The Experience Of Neurodivergent Individuals On Twitter (X) And Reddit, Kartik Thakkar Dec 2025

Social Media Mining For Extracting The Experience Of Neurodivergent Individuals On Twitter (X) And Reddit, Kartik Thakkar

All Graduate Theses and Dissertations, Fall 2023 to Present

Neurodiversity refers to the natural neurological variations in the human brain such as autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), dyslexia, dyspraxia, Tourette syndrome and other neurological disorders. it’s estimated that around 15% to 20% of the world’s population is neurodivergent. This means a significant portion of people experience neurological differences in how they think, learn, and interact with the world.

Social Media has become an important space for neurodivergent individuals to share their experiences, build communities, and seek support. This thesis explores how the online venues like X (Twitter) and Reddit offer themselves as digital spaces where …


Using Behavioral Skills Training To Teach School Staff To Implement Functional Communication Training, Megan Johnston Dec 2025

Using Behavioral Skills Training To Teach School Staff To Implement Functional Communication Training, Megan Johnston

All Graduate Theses and Dissertations, Fall 2023 to Present

This project looked at how to train school staff in effective strategies for supporting students with disabilities who engage in challenging behaviors like hitting, self-injury, or crying. We taught three school staff members to use a behavioral intervention called Functional Communication Training (FCT), which helps students learn more appropriate ways to communicate their needs, while also ensuring they do not gain access to reinforcement for challenging behaviors. Staff were trained using Behavioral Skills Training (BST), a step-by-step approach that includes instructions, modeling, practice, and feedback. After the training, the school staff were able to use these strategies correctly, and the …


Using Luminescence Of Quartz Temper From Archaeological Pottery To Infer Wildfire Intensity In The Southwestern Us, Brooklyn D. Dib Dec 2025

Using Luminescence Of Quartz Temper From Archaeological Pottery To Infer Wildfire Intensity In The Southwestern Us, Brooklyn D. Dib

All Graduate Theses and Dissertations, Fall 2023 to Present

The size and frequency of wildfires have increased recently, impacting ecosystems, communities, and human health. This research uses the heat-sensitive luminescence signals of quartz sand temper within archaeological pottery to record past wildfire conditions. Pottery sherds, which are fragments of archaeological pottery, from the forest floor in sites in New Mexico and Arizona were collected from different fire contexts (no fire exposure, historical fires, prescribed burns, and modern wildfires). These forests are primarily Ponderosa Pine with a grassy understory. The interior sand grains of each sherd sample were analyzed using optically stimulated luminescence, which dates when the mineral grains were …


Investigating Pyrethroid Insecticide Resistance In The Alfalfa Pest Insects Hypera Postica (Alfalfa Weevil) And Lygus Spp. (Lygus Bugs) In Utah Alfalfa Fields, Rosalie Sepesy Dec 2025

Investigating Pyrethroid Insecticide Resistance In The Alfalfa Pest Insects Hypera Postica (Alfalfa Weevil) And Lygus Spp. (Lygus Bugs) In Utah Alfalfa Fields, Rosalie Sepesy

All Graduate Theses and Dissertations, Fall 2023 to Present

Chemical insecticides are commonly used to manage the damage to crops caused by agricultural pest insects. Reliance on insecticides for pest management has resulted in insecticide resistance in many insect species worldwide. Alfalfa weevils (Hypera postica) and lygus bugs (species within the genus, Lygus), are major pests to alfalfa hay and seed respectively and cause significant economic damage. The goal of this dissertation was screen Utah alfalfa fields for resistant alfalfa weevil and lygus bug populations, investigate genetic mutations that can influence resistance in alfalfa weevils, and establish which species of lygus bugs are present in Utah …


Practical Effectiveness Of Large Language Models In Assisting Landscape Architects In Plant Selection, Paul Gardner Dec 2025

Practical Effectiveness Of Large Language Models In Assisting Landscape Architects In Plant Selection, Paul Gardner

All Graduate Theses and Dissertations, Fall 2023 to Present

Artificial intelligence (AI) is rapidly transforming many industries, but its role in landscape architecture remains relatively unexplored. This study examines how AI, specifically GPT-4, can assist landscape architects in selecting plants for projects. By comparing AI-generated plant lists to those that human experts created, the research evaluates Accuracy, Suitability, Availability, Aesthetics, and Professional Usability.

The results show that AI-generated plant lists were highly efficient, accurately matching site conditions and improving plant availability while significantly reducing selection time. However, human expertise was essential for ensuring aesthetic quality and design intent. While AI can serve as a powerful tool for streamlining plant …


An Evaluation Of Virtual Reality Modeling To Improve Accuracy Of Physical Education Skills In Teenage Students With Disabilities, Kristen Lee Dec 2025

An Evaluation Of Virtual Reality Modeling To Improve Accuracy Of Physical Education Skills In Teenage Students With Disabilities, Kristen Lee

All Graduate Theses and Dissertations, Fall 2023 to Present

Virtual Reality (VR) technology is becoming more common in schools, especially for teaching and training. In this study, researchers explored how VR can help teenagers with disabilities improve their physical education skills, specifically push-ups, lunges, and jumping jacks. The participants all showed an increase in their skills and reached a high level of accuracy on every skill. The results showed that adding feedback was also necessary for some participants. Additionally, participants enjoyed using the VR equipment and showed high levels of happiness throughout the study. These findings suggested that using VR technology can be an effective way to support teenagers …


Discourses Embedded In The Adams V. School Board Of St. Johns County Decision And The Rights Of Transgender Students In Schools, Douglas Larson Dec 2025

Discourses Embedded In The Adams V. School Board Of St. Johns County Decision And The Rights Of Transgender Students In Schools, Douglas Larson

All Graduate Theses and Dissertations, Fall 2023 to Present

This study was critical analysis of the language of the court case Adams v. School Board of St. Johns County (2022). This case was brough by a student against the School District challenging a policy that prevented him, a transgender boy, from using the boys’ restroom. The analysis was not intended to determine the merits of the case or the correctness of the legal reasoning. Rather, the analysis was performed on the text of the case—the language used by the judges—to learn about the beliefs, attitudes, and values of the judges.

The reason this analysis is important is because judges …


The Shifting Order Of Global Jurisprudence: Responses Of Intersectionality Towards Social And Economic Justice, Daniel Ketcher Dec 2025

The Shifting Order Of Global Jurisprudence: Responses Of Intersectionality Towards Social And Economic Justice, Daniel Ketcher

Faculty and Staff Publications & Presentations

This interdisciplinary study investigates how the second Trump administration is reshaping the capacity and legitimacy of central multilateral institutions and proposes a framework for Integrative Justice Governance ( IJG ) to counteract these effects. Guided by three research questions – projecting the budgetary and normative impacts on bodies such as the WHO, the WTO, and the ICC; identifying specific mechanisms of US disengagement; and testing the conditions under which IJG-based interventions could, in theoretical terms, offset the damage through concrete examples of implementation practices – the article advances three hypotheses: the renewed US withdrawal is causing measurable or observable declines …


More Than Peyote: Trauma, Healing, And The Politics Of Indigenous Cultural Survival In The Age Of Psychedelic Colonialism, Christine Diindiisi Mccleave Dec 2025

More Than Peyote: Trauma, Healing, And The Politics Of Indigenous Cultural Survival In The Age Of Psychedelic Colonialism, Christine Diindiisi Mccleave

Indigenous Studies

This dissertation examines the intersection of peyote religion, historical trauma, and the emergent psychedelic movement through a critical Indigenous lens. Centering peyote as both a sacred medicine and a symbolic flashpoint, the study highlights how contemporary psychedelic policy, practice, and commercialization perpetuate settler-colonial paradigms and threaten Indigenous cultural survival. While mainstream narratives frame psychedelics as tools for healing, this research emphasizes how such framing often obscures deeper histories of dispossession, cultural appropriation, and epistemic violence. Using a mixed-methods approach, including 50 anonymous survey responses, 13 qualitative interviews, and a 6-person focus group, this study amplifies the voices of tribal citizens …


Prevalence Of Mental Illness, Substance Use Disorder, And Dual Diagnosis Among Adults In Custody, Darcy J. Coulter, Lindsay A. Pearce, Matthew Legge, Jesse T. Young, David B. Preen, Ed C. Heffernan, Jocelyn D. Jones, Stuart A. Kinner Dec 2025

Prevalence Of Mental Illness, Substance Use Disorder, And Dual Diagnosis Among Adults In Custody, Darcy J. Coulter, Lindsay A. Pearce, Matthew Legge, Jesse T. Young, David B. Preen, Ed C. Heffernan, Jocelyn D. Jones, Stuart A. Kinner

Research outputs 2022 to 2026

Background: The prevalence of mental illness, substance use disorders, and their dual diagnosis is disproportionately high among people in prisons compared to the community. Accurate prevalence estimates are required to inform resourcing of prison health services and reduce the risk of harm to people experiencing these conditions. Existing estimates, where available, often rely on only one data source. Method: We used three data sources – self-reported history of diagnoses, in-prison medical records, and administrative data to estimate the prevalence of mental illness, substance use disorder, and dual diagnosis among two large cohorts of non-Indigenous and Aboriginal and Torres Strait Islander …


Book Review Of Douglass, J.A. (2021). Neo-Nationalism And Universities: Populists, Autocrats, And The Future Of Higher Education., Bhavika Sicka Dec 2025

Book Review Of Douglass, J.A. (2021). Neo-Nationalism And Universities: Populists, Autocrats, And The Future Of Higher Education., Bhavika Sicka

Journal of Comparative & International Higher Education

No abstract provided.


Perfectionism And Compulsive Exercise: A Systematic Review And Preliminary Meta-Analysis, Elizabeth Bills, Shannon R. Muir, Rose Stackpole, Sarah J. Egan Dec 2025

Perfectionism And Compulsive Exercise: A Systematic Review And Preliminary Meta-Analysis, Elizabeth Bills, Shannon R. Muir, Rose Stackpole, Sarah J. Egan

Research outputs 2022 to 2026

Purpose: There is a consistent link between perfectionism and compulsive exercise, and both are implicated in the maintenance of eating disorders, however no meta-analysis to date has quantified this relationship. We hypothesised that there would be significant, small-moderate pooled correlations between perfectionism dimensions and compulsive exercise. Methods: Published, peer-reviewed articles with standardised measures of perfectionism and the Compulsive Exercise Test were included. There were 7 studies included (N = 3117 participants, M age = 21.78 years, 49% female). Results: Total perfectionism (r = 0.37), perfectionistic strivings (r = 0.33), and perfectionistic concerns (r = 0.32) had significant pooled positive associations …


Profiling Of Igg N-Glycosylation For Axial Spondyloarthritis And Other Rheumatic Diseases, Xiaojia Xu, Zhixian Chen, Manshu Song, Zhiduo Hou, Lois Balmer, Chunbin Zhou, Yayi Huang, Haifeng Hou, Wei Wang, Ling Lin Dec 2025

Profiling Of Igg N-Glycosylation For Axial Spondyloarthritis And Other Rheumatic Diseases, Xiaojia Xu, Zhixian Chen, Manshu Song, Zhiduo Hou, Lois Balmer, Chunbin Zhou, Yayi Huang, Haifeng Hou, Wei Wang, Ling Lin

Research outputs 2022 to 2026

Background: Axial spondyloarthritis (axSpA) is an inflammatory rheumatic disease with challenges in diagnosis and disease activity assessment. While alterations in immunoglobulin G (IgG) N-glycosylation have been observed in varied rheumatic diseases, those in axSpA remains unclear. This study aims to explore the role of IgG N-glycan profiles in diagnosis and disease activity of axSpA. Methods: A clinical case-control study was conducted involving patients with axSpA (n = 138), systemic lupus erythematosus (n = 102), rheumatoid arthritis (n = 106), osteoarthritis (n = 33), gout (n = 41) and healthy controls (n = 117). Ultra-performance liquid chromatography was employed to analyze …