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2025

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Compensation Transparency In The U.S. Healthcare Workforce, Brandon Perkins Dec 2025

Compensation Transparency In The U.S. Healthcare Workforce, Brandon Perkins

Honors Projects

This study investigates how perceptions of pay transparency among U.S. healthcare workers relate to work engagement, burnout levels, and intentions to stay with their current institution. A quantitative survey was conducted of 200 clinical and non-clinical employees across academic, nonprofit, for-profit, and government healthcare organizations. Self-reported views of transparency were evaluated in relation to validated measures of work engagement, burnout, stay intentions, and pay secrecy. The results showed that increased perceived compensation transparency was highly connected with greater work engagement and lower levels of burnout. Both engagement and burnout appeared as major indicators of the employees' intentions to stay with …


Policy Design For Multiple Funding Flows Into Trump Accounts, Jin Huang, Michael Sherraden, Lissa Johnson Dec 2025

Policy Design For Multiple Funding Flows Into Trump Accounts, Jin Huang, Michael Sherraden, Lissa Johnson

Center for Social Development Research

The law creating the new Trump Accounts explicitly authorizes employers to provide deposits matching contributions that their employees make to the accounts and also authorizes contributions by philanthropic organizations. Both features are essential for build­ing substantial lifetime assets for America’s children. Implementing them successfully – and ensuring that the funds reach every eligible child efficiently – will require an effective policy platform for routing, verifying, and reporting on third-party contributions. This brief discusses why traditional retail IRAs cannot support matching contributions and how to build a policy platform capable of accommodating multiple contribution streams.


Ctrl + Alt + Inner Speech: A Verbal–Cognitive Scaffold (Vcs) Model Of Pathways To Computational Thinking, Daisuke Akiba Dec 2025

Ctrl + Alt + Inner Speech: A Verbal–Cognitive Scaffold (Vcs) Model Of Pathways To Computational Thinking, Daisuke Akiba

Publications and Research

This theoretical paper introduces the Verbal–Cognitive Scaffold (VCS) Model, a cognitively inclusive framework which proposes the cognitive architectures underlying computational thinking (CT). Moving beyond monolithic theories of cognition (e.g., executive-function and metacognitive control models), the VCS Model posits inner speech (InSp) as the predominant cognitive pathway supporting CT operations in neurotypical populations. Synthesizing interdisciplinary scholarship across cognitive science, computational theory, neurodiversity research, and others, this framework articulates distinct mechanisms through which InSp supports CT. The model specifies four primary pathways linking InSp to CT components: verbal working memory supporting decomposition, symbolic representation facilitating pattern recognition and abstraction, sequential processing enabling …


Access To Care Barriers To Sacral Neuromodulation Implantation In Adults With Overactive Bladder From Georgia, Tamara Lynn Wojciechowski Dec 2025

Access To Care Barriers To Sacral Neuromodulation Implantation In Adults With Overactive Bladder From Georgia, Tamara Lynn Wojciechowski

Walden Dissertations and Doctoral Studies

Sacral neuromodulation (SNM) is a safe and physically well-tolerated third-line treatment using an implantable device for the management of overactive bladder syndrome (OAB). Other first- and second-line treatments for OAB are frequently ineffective and often poorly tolerated. SNM implantation appears to be underutilized compared to other third-line treatments even though SNM has been rated more effective in OAB symptom mitigation with fewer side effects. Thus, the purpose of this quantitative correlational cross-sectional study was to explore whether health services factors are barriers to utilizing SNM implantation as the third-line treatment for OAB in adults. Andersen’s behavioral model of health services …


States As Shields, Lindsay F. Wiley Dec 2025

States As Shields, Lindsay F. Wiley

Minnesota Law Review Vols. 106:2 onward (2021-present)

State laws that aim to shield providers of reproductive health and gender-affirming care from the punitive actions of out-of-state officials raise thorny questions. Can the federal courts, Congress, or the Trump Administration require New York officials to enforce a Texas ban on abortion or gender-affirming care against a New York doctor who prescribed medication to a patient in Texas via telehealth? If so, how might New Yorkers’ access to health care be affected? If not, will interstate commerce and travel preserve some degree of access for Texans?

Disputes over reproductive health and gender-affirming care are putting new pressure on doctrines …


Quality Improvement Project: Provider Education On An Evidence-Based Clinical Pathway For Diagnosing Adult Attention-Deficit Hyperactivity Disorder, Oluwadayo B. Adeyemo Dec 2025

Quality Improvement Project: Provider Education On An Evidence-Based Clinical Pathway For Diagnosing Adult Attention-Deficit Hyperactivity Disorder, Oluwadayo B. Adeyemo

Doctor of Nursing Practice Projects

Accurate diagnosis of adult Attention-Deficit Hyperactivity Disorder (ADHD) remains challenging in outpatient behavioral health settings, as variations in clinician training, diagnostic tools, and assessment methods can hinder accuracy and delay treatment. At the project site, providers reported low confidence and inconsistent use of standardized tools when evaluating adult ADHD, underscoring a critical need for structured education to improve diagnostic consistency and provider confidence. This quality-improvement (QI) project assessed the impact of an educational intervention on provider knowledge, confidence, and utilization of validated screening tools for adult ADHD. Guided by Donabedian’s Model of Quality Improvement and Lewin’s Change Theory, the project …


Quality Improvement Project: The Impact Of Genetic Testing Education For Mental Health Providers In An Outpatient Clinic, Ifeoma Uzoh-Anigbogu Dec 2025

Quality Improvement Project: The Impact Of Genetic Testing Education For Mental Health Providers In An Outpatient Clinic, Ifeoma Uzoh-Anigbogu

Doctor of Nursing Practice Projects

Despite growing evidence supporting the use of genetic screening in psychiatric medication management, many mental health providers lack the confidence and knowledge to utilize this tool effectively. This quality improvement (QI) project aimed to enhance provider self-efficacy and increase the utilization of genetic screening through a structured education and training program in an outpatient mental health clinic. The purpose of the project was to determine whether provider education on pharmacogenetic testing improves confidence and screening frequency compared to those who do not receive the intervention. The Donabedian Model guided evaluation of structure, process, and outcome measures, while Rogers’ Diffusion of …


Quality Improvement Project, Communicating With The Dying Patient: A Simulation Experience For Nursing Students, Jason Weger Dec 2025

Quality Improvement Project, Communicating With The Dying Patient: A Simulation Experience For Nursing Students, Jason Weger

Doctor of Nursing Practice Projects

Effective communication with patients near the end of life is a crucial yet often underdeveloped skill among nursing students. Previous research highlights a persistent gap in training for end-of-life communication in nursing schools. This quality improvement project implemented a simulation-based educational intervention to improve end-of-life communication skills among first-semester nursing students at a community college in Oklahoma. A needs assessment identified significant gaps in students' readiness for emotionally charged patient interactions. Guided by Prosci’s Change Model and Jeffries Simulation Theory, the project used a faculty-led simulation experience to teach evidence-based communication strategies, including appropriate word choice, therapeutic presence, and active …


Quality Improvement Project: Reducing Hospitalizations In The Long-Term Care Setting, Nenna Nzeocha Dec 2025

Quality Improvement Project: Reducing Hospitalizations In The Long-Term Care Setting, Nenna Nzeocha

Doctor of Nursing Practice Projects

Hospitalizations in the long-term care setting can lead to higher costs incurred by skilled nursing home residents and a poorer quality of life. This quality improvement (QI) project evaluated whether an educational intervention on the Reducing Avoidable Facility Transfers (RAFT) model impacted hospitalization rates in the skilled nursing facility (SNF), while also assessing the confidence level of facility staff on the intervention. The project utilized Lewin’s change theory and the Donabedian model framework and was aimed at developing interventions that impact hospitalizations in the SNF using the RAFT model. A quasi-experimental design was used and consisted of a pre-and-post implementation …


Quality Improvement Project: Development And Implementation Of A Structured Certification Support Program And The Impact On Nurses’ Confidence And Medical Surgical Certification Rates, Mary Tran Dec 2025

Quality Improvement Project: Development And Implementation Of A Structured Certification Support Program And The Impact On Nurses’ Confidence And Medical Surgical Certification Rates, Mary Tran

Doctor of Nursing Practice Projects

Professional nursing certification is an important criterion of Magnet designation, and increased certification rates have been associated with positive patient outcomes. The literature supports peer support and group study as beneficial strategies to assist nurses in preparing for certification exams. A quality improvement project among medical-surgical (med-surg) nurses at a community hospital pursuing Magnet redesignation addressed the lack of formal processes and nursing perceived barriers to certification that may contribute to low certification rates. The purpose of this project was to develop and implement a structured medical-surgical certification support program following the Plan-Do-Study-Act (PDSA) cycle utilizing evidence-based strategies, including a …


Quality Improvement Project: Improving Nurse Competency In Caring For Patients With Dementia With Behavioral Disturbances In Long-Term Care, Lashunta Jackson Dec 2025

Quality Improvement Project: Improving Nurse Competency In Caring For Patients With Dementia With Behavioral Disturbances In Long-Term Care, Lashunta Jackson

Doctor of Nursing Practice Projects

Dementia-related behavioral and psychological symptoms (BPSD) present major challenges for nurses in long-term care settings, often leading to inconsistent care, staff stress, and safety risks. Evidence-based, person-centered interventions are proven to improve outcomes but are frequently underutilized due to limited staff training. The purpose of this Doctor of Nursing Practice (DNP) project was to improve nursing staff competency in managing residents with dementia and behavioral disturbances through structured, evidence-based education. The problem identified was a lack of dementia-specific knowledge and confidence among nurses, which contributed to suboptimal care and increased behavioral incidents. A quasi-experimental pre-/post-intervention design guided by Knowles’ Adult …


Improving Self-Efficacy Among Clinical Instructors: The Impact Of Communication Education On Handling Lateral Violence, Emma Guidry Dec 2025

Improving Self-Efficacy Among Clinical Instructors: The Impact Of Communication Education On Handling Lateral Violence, Emma Guidry

Doctor of Nursing Practice Projects

The quality improvement (QI) project aims to determine if clinical instructors perceive changes in self-efficacy in communication skills specific to lateral violence (LV) situations secondary to an educational intervention. Currently, clinical nurse instructors lack education specifically addressing communication strategies to utilize when LV occurs in the clinical setting. Banduras Social Cognitive Theory, Lewin’s Change Theory and the Plan-Do-Study-Act (PDSA) were employed as frameworks in the development of this project. Methods used in this quasi-experimental design project include administration of the Self Efficacy to Address Disruptive Behaviors Scale (SADBS) survey to project participants, nursing clinical instructors. The evidence-based practice (EBP) intervention …


Resiliency For Nurse Educators: Incorporating Resiliency Training For Nursing Faculty, Rachael Holder Dec 2025

Resiliency For Nurse Educators: Incorporating Resiliency Training For Nursing Faculty, Rachael Holder

Doctor of Nursing Practice Projects

Nursing faculty frequently experience high levels of stress, workload demands, and burnout, which can negatively affect teaching effectiveness and retention. Literature supports resilience as a protective factor that enhances well-being and professional sustainability. The purpose of this quality improvement project was to impact resilience levels among full-time undergraduate nursing faculty through a self-paced online resiliency training program. Guided by Pender’s Health Promotion Model and Lewin’s Change Theory, this pre- and post-intervention design used the 10-item Connor-Davidson Resilience Scale (CD-RISC-10) to assess changes in resilience. Eleven faculty members completed the pre-survey, and two completed the post-survey. The post-survey mean CD-RISC-10 scores …


Quality Improvement Project Implementation Of A Peer Mentoring Program In An Associate-Degree Nursing Program, Heather Baker Dec 2025

Quality Improvement Project Implementation Of A Peer Mentoring Program In An Associate-Degree Nursing Program, Heather Baker

Doctor of Nursing Practice Projects

Peer mentoring is recognized as an evidence-based strategy that offers support to students and enhances retention. This project aimed to implement a peer mentoring program based on the Nursing Universal Retention and Success (NURS) model. The Plan-Do-Study-Act (PDSA) framework and Havelock’s Theory of Planned Change guided the implementation process. The goal was to assess the program's impact on first-semester nursing student retention rates and students’ perceptions of success. First-semester nursing students in a traditional associate-degree nursing program volunteered to participate in the peer mentoring program for one semester. At the end of the semester, an anonymous post-survey was distributed to …


Quality Improvement Project: Improving Emergency Medication Administration Safety In An Inpatient Psychiatric Unit, Sandra Anusiem Dec 2025

Quality Improvement Project: Improving Emergency Medication Administration Safety In An Inpatient Psychiatric Unit, Sandra Anusiem

Doctor of Nursing Practice Projects

Psychiatric emergencies contribute to medication safety issues due to increased stress, inconsistent practices, and communication breakdowns. The problem was high rates of medication errors in psychiatric emergencies due to the lack of a structured, standardized medication management protocol. This Doctor of Nursing Practice (DNP) quality improvement project aimed to reduce medication errors in administering emergency medications in an inpatient psychiatric unit by using the Medication Administration Cross-Check (MACC) checklist. The project was completed using a quasi-experimental research design guided by the Donabedian Model of Healthcare Quality and Lewin’s Change Model. Pretest and posttest knowledge, confidence, attitude, and perceptions were obtained …


Human Trafficking Simulation: Educational Tool For Developing Interprofessional Competencies, Kerri Anne Irwin, Kelly D. Caskey Dec 2025

Human Trafficking Simulation: Educational Tool For Developing Interprofessional Competencies, Kerri Anne Irwin, Kelly D. Caskey

Biennial Convention (CONV)

Introduction: This research is in response to the human trafficking (HT) crisis. HT affects an estimated 30 million people worldwide. Nurses are one of the few constant contacts within the hospital for these isolated victims. HT patients may feel protected under the trusted care of nurses (Morris, 2023). Raker (2023) found that “academic nursing programs represent an ideal environment to deliver human trafficking training to future graduate nurses.” The limited instruction for students led us to create an HT simulation that is being taught in a senior level nursing course.
The purpose of this research is to address the growing …


The Impact Of Infrastructure Construction And Remodeling Of Cities On Its People' Quality Of Life Miraj District-(Madi-Cairo) As A Geological Heritage Area, Ahmed M.E. Hammad Dec 2025

The Impact Of Infrastructure Construction And Remodeling Of Cities On Its People' Quality Of Life Miraj District-(Madi-Cairo) As A Geological Heritage Area, Ahmed M.E. Hammad

Mansoura Engineering Journal

Rapid urbanization is increasing globally, the urbanization rate expected to rise to more than 66% by 2050. (According to UN estimates) the increasing rates of urbanization in the world means adding 2.5 billion people to the urban population within a short period. Which necessitates increasing the traffic axes and the rest of the networks in terms of lengths and widths within the existing cities, and with the presence of the population during these works - despite their inevitability - the quality of their urban life is affected socially, naturally and economically. the research monitors these effects and the extent of …


Kinship Infrastructure Design: Evaluating Diversity And Resilience In Emergency Response Systems Through Agent-Based Modeling, Fayruz Maysha Dec 2025

Kinship Infrastructure Design: Evaluating Diversity And Resilience In Emergency Response Systems Through Agent-Based Modeling, Fayruz Maysha

Doctoral Dissertations and Master's Theses

Traditional infrastructure systems are often designed for predictable scenarios, making them vulnerable to disruption when real-world conditions change unexpectedly. This research addresses that limitation by introducing Kinship Infrastructure Design (KID), a bioinspired framework based on the kinship coefficient (Φ). Adapted from studies of genetic relatedness in eusocial insects, the kinship coefficient (Φ) measures similarity and diversity among system components by calculating the degree to which their functional traits—encoded as a synthetic genome—match. This research investigates whether a system design can achieve a “Goldilocks Zone” of functional diversity where systems achieve optimal adaptability and coordination under uncertainty."

Rather than relying on …


The Misunderstood Election Of 1876 And Colorado's Rocky Quest For Statehood, Maxwell D. Rotbart Dec 2025

The Misunderstood Election Of 1876 And Colorado's Rocky Quest For Statehood, Maxwell D. Rotbart

History Theses, Dissertations, and Student Creative Activity

On December 8, 1873, Representative Jerome B. Chaffee, the non-voting delegate of the Colorado Territory, submitted a proposal in the House of Representatives to make Colorado the 38th state in the Union. What should have been a routine matter — Colorado had the sizable population and economic stability necessary to achieve statehood — dragged on for more than three years. At stake was the outcome of the 1876 presidential election, in which Colorado’s electoral votes had the potential to — and ultimately did — decide which party would control the Executive Branch into the 1880s.

When historians consider the factors …


Establishing And Maintaining Equitable Leadership Practices In Nursing Education: A Way Forward, Joshua Michael Kies, Kari Mau Dec 2025

Establishing And Maintaining Equitable Leadership Practices In Nursing Education: A Way Forward, Joshua Michael Kies, Kari Mau

Biennial Convention (CONV)

There is currently a lack of diverse leadership in nursing education. This reflects multi-faceted systemic challenges that require innovative and comprehensive interventions. Current academic environments may perpetuate structures that marginalize faculty from underrepresented groups, creating significant barriers to equitable advancement and representation (Christensen, 2023).

The presentation will investigate the foundational principles of leadership development, focusing on transformative approaches that address inequities using recent research. Analyzing current demographic situations, institutional barriers, and perceived professional expectations, the discussion will uncover critical intervention points for long-term, meaningful change (Brown-DeVeaux & Glassman, 2023).

The critical importance of intentional, systemic interventions that move beyond “standardized” …


Current Practices In Undergraduate Nursing Honors Research Programs, Deanna L. Reising, Jessie Cheziwa Dec 2025

Current Practices In Undergraduate Nursing Honors Research Programs, Deanna L. Reising, Jessie Cheziwa

Biennial Convention (CONV)

Purpose/Background/Significance: Undergraduate nursing honors research programs are a method for increasing the desire for students to pursue graduate education for eventual research careers. The purpose of this study was to identify and describe the types and outcomes of undergraduate nursing honors research programs in the U.S.

Methods: A qualitative descriptive design using content analysis for data analysis. Faculty who were involved in undergraduate nursing honors research programs in the U.S. were recruited to complete an interview that elicited responses on the type and structure of the program, barriers to implementation, faculty workload models, and outcomes realized from the program.

Results: …


Establishing Nursing Excellence: A Quality Improvement Approach To Nursing Administration Evaluation Using Frontline Feedback, Meredith Sykora Dec 2025

Establishing Nursing Excellence: A Quality Improvement Approach To Nursing Administration Evaluation Using Frontline Feedback, Meredith Sykora

Doctor of Nursing Practice Projects

In the increasingly complex environment of nursing education, leadership quality and responsiveness significantly influence workplace culture, faculty satisfaction, professional development, and student outcomes. Despite these realities, many academic nursing programs, including the Division of Nursing at a community college in Arkansas, lack formal structures for bidirectional leadership evaluation. This gap limits frontline faculty’s ability to provide formative feedback to program leaders, weakening shared governance and transparency. The purpose of this quality improvement project was to evaluate leadership effectiveness following the implementation of a structured bidirectional feedback process between nursing faculty and program leaders. Guided by Kouzes and Posner’s Leadership Practices …


Final Butte Mine Waste Repository Geotechnical Investigation Work Plan, Pioneer Technical Services, Inc. Dec 2025

Final Butte Mine Waste Repository Geotechnical Investigation Work Plan, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


More Girls In The Classroom Improves Adolescent Mental Health, Monica Deza, Maria Zhu Dec 2025

More Girls In The Classroom Improves Adolescent Mental Health, Monica Deza, Maria Zhu

Population Health Research Brief Series

Mental health challenges are common among adolescents in the United States. This brief summarizes findings from a study using data from the National Longitudinal Study of Adolescent Health (Add Health), a nationally representative survey of middle and high school students conducted in 1994-1995. The analysis included over 17,000 students from 133 schools across the United States. The authors find that the mix of boys and girls in a classroom affects adolescent mental health and school satisfaction. When classes have more girls, both boys and girls experience better mental health outcomes. Boys in classes with more female peers are 10% less …


Reducing Falls In The Acute Care Setting: A Quality Improvement Project, Elorm M. Adzokpa Dec 2025

Reducing Falls In The Acute Care Setting: A Quality Improvement Project, Elorm M. Adzokpa

Doctor of Nursing Practice Final Project Abstract

Falls remain one of the most common adverse events in acute care settings and are associated with increased morbidity, extended hospital stays, and higher healthcare costs. Orthopedic and trauma patients are particularly vulnerable due to mobility limitations, postoperative recovery, and complex medical conditions. The purpose of this quality improvement project was to reduce inpatient falls on an adult orthopedic and trauma unit by implementing a visual aid to reinforce the 5P fall-prevention framework. A pre–post quality improvement design was used during an eight-week implementation period. The intervention included a standardized fall prevention bundle that reinforced existing Fall TIPS board use …


New Unh Certificate Prepares Social Workers To Support Student Mental Health, Aaron Sanborn Dec 2025

New Unh Certificate Prepares Social Workers To Support Student Mental Health, Aaron Sanborn

UNH Today Archive

No abstract provided.


"Pollution Does Not [Sic] Discriminate": Louisiana V. Epa, Disparate Impact, And The Fight For Environmental Justice In A Hostile Climate, Naomi Brim Dec 2025

"Pollution Does Not [Sic] Discriminate": Louisiana V. Epa, Disparate Impact, And The Fight For Environmental Justice In A Hostile Climate, Naomi Brim

Minnesota Law Review Vols. 106:2 onward (2021-present)

Human-induced climate change hurts people. Environmental burdens impact a person’s ability to live freely, in good health, and with loved ones. And in the United States, people in positions of political authority and decision-making—who are predominantly white and high-income—use the legal system to push environmental harms disproportionately onto low-income, Black, Indigenous, People of Color (BIPOC) communities. This has occurred for centuries and continues in the present. A basic sense of justice makes the following conclusion easy to reach: skin color, zip code, and pocketbook should not determine whether someone enjoys a clean and healthful environment.

For plaintiffs seeking relief from …


Public Priorities For The Post-War Reconstruction Of Ukraine’S Energy Sector., Olena Savchenko, Vasyl Zhelykh, Khrystyna Kozak, Omar Al-Hafith, Joao Alencastro, Olugbenga Oladinrin, Ademola Adebayo Akinbami Dec 2025

Public Priorities For The Post-War Reconstruction Of Ukraine’S Energy Sector., Olena Savchenko, Vasyl Zhelykh, Khrystyna Kozak, Omar Al-Hafith, Joao Alencastro, Olugbenga Oladinrin, Ademola Adebayo Akinbami

School of Art, Design and Architecture

The Russian invasion of Ukraine has resulted in the large-scale destruction of many cities across the country. Although the war has not yet ended, there will come a time when the conflict concludes, and reconstruction efforts will begin. Global experiences show that the first step in preparing for post-war reconstruction is to assess the level of destruction. Additionally, it is essential to understand people’s needs and priorities. Otherwise, reconstruction activities may fail to address the existing challenges and actual needs of local communities. This study aims to explore post-war reconstruction priorities of Ukrainians, with special focus on the energy sector …


Fabrication And Evaluation Of Large Alumina Crucibles By Vat Photopolymerization Additive Manufacturing For High-Temperature Actinide Chemistry, R. Joey Griffiths, Christy Santoyo, Jean-Baptise Forien, Bradley Childs, Andrew J. Swift, Andrew Cho, Alexander Wilson-Heid, George Ankrah, Devin Rappleye, Aiden A. Martin, Jason Jeffries, Kiel Holliday Dec 2025

Fabrication And Evaluation Of Large Alumina Crucibles By Vat Photopolymerization Additive Manufacturing For High-Temperature Actinide Chemistry, R. Joey Griffiths, Christy Santoyo, Jean-Baptise Forien, Bradley Childs, Andrew J. Swift, Andrew Cho, Alexander Wilson-Heid, George Ankrah, Devin Rappleye, Aiden A. Martin, Jason Jeffries, Kiel Holliday

Faculty Publications

Additive manufacturing (AM) offers opportunities to advance the design and function of ceramic tooling in high temperature actinide pyrochemistry. In technical ceramics such as alumina, conventional forming techniques often restrict design flexibility and can limit experimental progress. In this study, we investigate the use of vat photopolymerization (VP) with commercial resins to fabricate large-scale alumina crucibles, reaching dimensions up to 125 mm, which is significantly larger than typically reported for dense VP ceramics. Notably, these additively manufactured components are produced using consumer-grade hardware, which limits process control, but offers significant upside in scalability and accessibility. Using microscopy and X-ray computed …


Activation Of Pro-Regenerative Gene Programs In The Mature Central Nervous System, Elizabeth Carlisle Batsel Dec 2025

Activation Of Pro-Regenerative Gene Programs In The Mature Central Nervous System, Elizabeth Carlisle Batsel

Dissertations (1934 -)

Spinal cord injury (SCI) affects millions of people worldwide. Damage to the spinal cord disrupts the long-distance axon tracts of central nervous system (CNS) neurons. These axons fail to regenerate, leading to permanent dysfunction. Past work has shown that CNS neurons lose the capacity to elongate their axons as they mature. Conversely, after injury, embryonic and peripheral nervous system (PNS) neurons can elongate axons towards target cells, driven by the growth cone at the growing tip of the axon. Previous research has identified transcription factor (TF) families, such as the SoxC family, that contribute to embryonic and peripheral neurons’ high …