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2025

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2025 Joint Journal Between Witness And The Great Commission Research Journal, Thomas Seckler, David Dunaetz Nov 2025

2025 Joint Journal Between Witness And The Great Commission Research Journal, Thomas Seckler, David Dunaetz

Witness

No abstract provided.


Pauline Style And A Biblical Theology, Andrew Whitney Perkins Nov 2025

Pauline Style And A Biblical Theology, Andrew Whitney Perkins

Masters Theses

Advances in biblical linguistics, especially in the Greek of the New Testament, have provided a means for a better understanding of the text of Scripture. Advances in Greek lexicography, syntax, verbal aspect, discourse analysis, exegetical and hermeneutical methods, and the historical background behind the gospels and letters of the New Testament have greatly increased interpreters’ ability to determine what the text meant from both the writers and to the recipients of those documents. However, Christian theology, especially Systematic Theology, has remained mostly static, unaffected by these advances, and by a more accurate understanding of the biblical text. This thesis affirms …


Desegregated Goals: Integrating Literacy And Behavioral Health In A Community Mental Health Setting To Improve Outcomes For Middle School Students, Donna M. Reed Nov 2025

Desegregated Goals: Integrating Literacy And Behavioral Health In A Community Mental Health Setting To Improve Outcomes For Middle School Students, Donna M. Reed

Masters Theses

Despite an understanding that many at-risk students lack the reading and writing skills to navigate high school and post-secondary education successfully, current interventions are often inadequate. Schools are forced to focus on academic requirements, while other needs of the student are overlooked, and it is those overlooked needs that contribute to the educational failures of the student. This thesis presents an argument for holistic support of the at-risk student when remediating academics, specifically reading and writing skills, focusing on the middle school students of a rural middle school in central Kansas. It develops a curriculum that integrates physical and mental …


Hawk's Herald -- November 13, 2025, Roger Williams University Nov 2025

Hawk's Herald -- November 13, 2025, Roger Williams University

Hawk's Herald

No abstract provided.


From Disruption To Renewal: Harnessing Divine Interruptions And Strategic Leadership For Transforming Church Culture, Ryan Johnson Nov 2025

From Disruption To Renewal: Harnessing Divine Interruptions And Strategic Leadership For Transforming Church Culture, Ryan Johnson

Witness

No abstract provided.


Life In The Kingdom: Reimagining Theological Education For A Post-Secular Global Age, Jose Philip Nov 2025

Life In The Kingdom: Reimagining Theological Education For A Post-Secular Global Age, Jose Philip

Witness

No abstract provided.


Joint Journal Between Witness And The Great Commission Research Journal 2025, Thomas W. Seckler, David Dunaetz Nov 2025

Joint Journal Between Witness And The Great Commission Research Journal 2025, Thomas W. Seckler, David Dunaetz

Witness

No abstract provided.


Black Grouper (Mycteroperca Bonaci) Neurocranium, Layla Lacelle, David W. Kerstetter Nov 2025

Black Grouper (Mycteroperca Bonaci) Neurocranium, Layla Lacelle, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.


The Cowl - V. 89 N. 8 - November 13, 2025 Nov 2025

The Cowl - V. 89 N. 8 - November 13, 2025

The Cowl

The Cowl - student newspaper of Providence College. Vol. 89 No. 8 - November 13, 2025. 20 pages.


Rabies Virus-Vectored Lyme Disease Vaccine Provides Long-Term Protection Against Tick-Transmitted Borrelia Burgdorferi, Shantel Rios, Bibek Bhattachan, Christoph Wirblich, Anisha Chandwani, Kruthi Vavilikolanu, Jacob F. Myers, Chrysoula Kitsou, Utpal Pal, Matthias J. Schnell Nov 2025

Rabies Virus-Vectored Lyme Disease Vaccine Provides Long-Term Protection Against Tick-Transmitted Borrelia Burgdorferi, Shantel Rios, Bibek Bhattachan, Christoph Wirblich, Anisha Chandwani, Kruthi Vavilikolanu, Jacob F. Myers, Chrysoula Kitsou, Utpal Pal, Matthias J. Schnell

Department of Microbiology and Immunology Faculty Papers

Lyme disease (LD) cases have doubled globally. LD is a tick-borne illness caused by the Borrelia burgdorferi sensu lato (Bb). If untreated, Bb can disseminate to distal organs, causing carditis, arthritis, and meningitis. Currently, no FDA-approved human LD vaccine exists on the market. This study used two approaches to incorporate OspA into the rabies virus (RABV) vaccine vector. We used the RABV-glycoprotein tail (RVG tail) and the Hendra virus (HeV) glycoprotein tail (HVG tail) to incorporate OspA, creating BNSP333-OspA-RVG and BNSP333-OspA-HVG, respectively. Both vaccines produced type-1 biased anti-OspA antibodies, but only BNSP333-OspA-HVG induced neutralizing antibodies and protected against Bb infection. …


The Colby Echo (2025-11-13), Colby College Nov 2025

The Colby Echo (2025-11-13), Colby College

The Colby Echo

Published by the students of Colby College since 1877, The Colby Echo is the weekly, editorially independent student-run newspaper of Colby College in Waterville, Maine. Published monthly, 1877-1886; semi-monthly, 1886-1897; and weekly during the academic year, 1898-present.


A Phenomenological Study On The Influence Of Teacher Perceptions On Play-Based Learning, Courtney Simpson Nov 2025

A Phenomenological Study On The Influence Of Teacher Perceptions On Play-Based Learning, Courtney Simpson

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to describe the lived experiences of implementing play-based learning for teachers at early childhood settings in Georgia. The theory guiding this study was Jon Dewey’s theory of experiential learning, as it addressed the significance of children learning through play. The Central Research Question was: What are the experiences of teachers implementing play-based learning in early childhood settings in Georgia? A qualitative methodology approach utilizing transcendental phenomenology was taken to describe the lived experiences of 13 teachers implementing play-based learning. The setting included early learning centers and schools in Georgia. A combination of snowball …


Secondary Teacher Experiences Of Classically Taught Students’ Social-Emotional Development: A Hermeneutic Phenomenology, Kirby Elizabeth Donaldson Nov 2025

Secondary Teacher Experiences Of Classically Taught Students’ Social-Emotional Development: A Hermeneutic Phenomenology, Kirby Elizabeth Donaldson

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to interpret the experiences of 7th-12th grade educators at George Washington Academy who teach solely through classic literature and primary accounts of historical and social significance, focusing on their perceptions of their students’ social and emotional development. The theory that guided this study was Erikson’s psychosocial development theory, which provided a framework for appropriate social-emotional development across all ages. The central research question was, “What are the experiences of secondary (7th-12th grade) educators who utilize classic literature and primary accounts of historical and social significance regarding their students’ psychosocial development?” The phenomenological …


Atonement As The Path To Holiness: The Suffering Servant Of The Fourth Servant Song As The Missing Sacrifice Of Isaiah 6, William Anthony Whitfield Nov 2025

Atonement As The Path To Holiness: The Suffering Servant Of The Fourth Servant Song As The Missing Sacrifice Of Isaiah 6, William Anthony Whitfield

Doctoral Dissertations and Projects

This study argues that the Suffering Servant of the Fourth Servant Song (SS4, Isaiah 52:13-53:12) is the missing sacrifice of Isaiah 6. This conclusion is supported by the multitude of intertextual links between these two hallmark texts of Isaiah, including language of exaltation, messianic imagery, and, most notably to the current study, atonement imagery, specifically as it relates to being an avenue to holiness. This study addresses the necessity for a sacrifice in Isaiah 6, although no sacrifice is explicitly mentioned. Atonement is the central theme of SS4, where the Suffering Servant is depicted as being given as a guilt …


Untethered Spiritual Care: Fortifying Warfighter Fitness In The Era Of Great Power Competition, Charles R. Bruner Nov 2025

Untethered Spiritual Care: Fortifying Warfighter Fitness In The Era Of Great Power Competition, Charles R. Bruner

Doctoral Dissertations and Projects

As the operational paradigm shifts from the large counter-insurgency missions of the Global War on Terror to agile combat employment characterized by untethered operations in potential locations such as the Pacific Theater, robust spiritual fitness will become increasingly more vital. Those most at risk for spiritual wounding and moral injury due to their experiences will be Airmen assigned to small, forward-deployed Mission Ready Airman (MRA) teams who must generate combat aircraft in austere locations with minimal supplies and far from support, including religious and spiritual support. This research project examines the problem of providing effective, robust point-of-care spiritual support without …


U.S. Navy Spacecraft Recovery Operations, 1957-1961, Marc Robert Henderson Nov 2025

U.S. Navy Spacecraft Recovery Operations, 1957-1961, Marc Robert Henderson

Doctoral Dissertations and Projects

The purpose of this study is to highlight U.S. Navy efforts during early space recovery operations. The space recovery mission was new to the United States’ Cold War Navy, and in many cases its space recovery forces learned through trial and error, beginning with Jupiter missile nosecone recoveries in 1957. The study examines the collaborative efforts between the U.S. Navy and the National Aeronautics and Space Administration to locate and retrieve Project Mercury astronauts and space capsules after they traveled into space and splashed down in the ocean. It identifies technological aides on which recovery forces led by the U.S. …


Spartan Daily, November 13, 2025, San Jose State University, School Of Journalism And Mass Communications Nov 2025

Spartan Daily, November 13, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 35


Developing A General Ai Model For Integrating Diverse Genomic Modalities And Comprehensive Genomic Knowledge, Zhenhao Zhang, Xinyu Bao, Linghua Jiang, Xin Luo, Zheyu Zhang, Jing Yin, Meiqi Zhao, Yichun Wang, Annelise Comai, Joerg Waldhaus, Anders S Hansen, Wenbo Li, Jie Liu Nov 2025

Developing A General Ai Model For Integrating Diverse Genomic Modalities And Comprehensive Genomic Knowledge, Zhenhao Zhang, Xinyu Bao, Linghua Jiang, Xin Luo, Zheyu Zhang, Jing Yin, Meiqi Zhao, Yichun Wang, Annelise Comai, Joerg Waldhaus, Anders S Hansen, Wenbo Li, Jie Liu

Faculty, Staff and Student Publications

Advances in next-generation sequencing technologies have vastly expanded the availability of diverse genomic, epigenomic, and transcriptomic data, presenting the opportunity to develop a general AI model that integrates comprehensive genomic knowledge into a unified model. Unlike previous predictive models, which are typically specialized to certain tasks, our general AI model unifies a wide range of genomic modalities, such as nascent RNA and ultra-high-resolution chromatin organization, within a multi-task architecture. Using ATAC-seq and DNA sequences as inputs, we incorporated diverse genomic modalities as output, and the model exhibits strong generalizability across different cell types and tissues in all tasks we trained. …


The Unfolded Protein Response-Novel Mechanisms, Challenges, And Key Considerations For Therapeutic Intervention, P M Quan Mai, Tam-Anh Truong, Sai Kumar Samala, Bhoomika Muruvekere Lakshmisha, Prapannajeet Biswal, Khadijeh Koushki, Prudhvi Chand Mallepaddi, Geraldine Vijay, Sunil Krishnan Nov 2025

The Unfolded Protein Response-Novel Mechanisms, Challenges, And Key Considerations For Therapeutic Intervention, P M Quan Mai, Tam-Anh Truong, Sai Kumar Samala, Bhoomika Muruvekere Lakshmisha, Prapannajeet Biswal, Khadijeh Koushki, Prudhvi Chand Mallepaddi, Geraldine Vijay, Sunil Krishnan

Faculty, Staff and Student Publications

Background: The unfolded protein response (UPR) is an evolutionarily conserved, synchronized, and orchestrated process triggered by eukaryotic cells in response to endoplasmic reticulum (ER) stress. UPR restores the ER's capacity to handle large protein loads within it, and still fold and process these proteins accurately. Many recent studies have documented the non-canonical roles of the UPR, outside of protein quality control, in the context of lipid metabolism and the immune system in cancer. Cancer cells have been known to hijack the UPR to promote survival and evade immune surveillance. However, the underlying mechanisms remain poorly understood.

Objectives: Here, we critically …


Cold Forged: A Theological Reckoning In Narrative Silence, Craig Steven Wright Nov 2025

Cold Forged: A Theological Reckoning In Narrative Silence, Craig Steven Wright

Masters Theses

This thesis examines the construction of testimonial fiction as an act of moral resistance and theological witness, developed through a creative manuscript (Cold Forged) that embodies a cruciform narrative structure modelled on Isaiah 53 and the Book of Job. The project interrogates institutional betrayal, memory as liturgy, and the intersection of silence and suffering, situating itself within a literary genealogy that includes Flannery O’Connor, Fyodor Dostoevsky, Cormac McCarthy, and C.S. Lewis. The critical paper will explore the aesthetics of theological realism in trauma narrative, and the artist statement will defend the cruciform architecture of narrative silence as an ethical form.


A Phenomenological And Transcendental Study Of The Lived Experiences Of Mental Health Practitioners Acquiring The Competencies To Become A Sandtray Therapy Practitioner, Deborah Kay Webb-Johnson Nov 2025

A Phenomenological And Transcendental Study Of The Lived Experiences Of Mental Health Practitioners Acquiring The Competencies To Become A Sandtray Therapy Practitioner, Deborah Kay Webb-Johnson

Doctoral Dissertations and Projects

The purpose of this qualitative, phenomenological, transcendental study was to describe the lived experiences of 16 mental health practitioners in North America who acquired competencies through various training programs or certification courses to proficiently integrate sandtray therapy as a cross-theoretical approach. Through semi-structured interviews and focus group discussions, participants described how they developed the competencies and standards to integrate sandtray therapy as a cross-theoretical approach with diverse populations, while also engaging in dialogue about the need for greater governance and regulation of training programs. The theoretical framework for this study was based on Husserl’s theory of transcendental phenomenology and the …


Comparing Machine Learning, Deep Learning, And Reinforcement Learning Performance In Culex Pipiens Predictive Modeling, Wei Yin, Sanad H. Ragab, Michael G. Tyshenko, Teresa Patricia Feria-Arroyo, Tamer Oraby Nov 2025

Comparing Machine Learning, Deep Learning, And Reinforcement Learning Performance In Culex Pipiens Predictive Modeling, Wei Yin, Sanad H. Ragab, Michael G. Tyshenko, Teresa Patricia Feria-Arroyo, Tamer Oraby

School of Mathematical & Statistical Sciences Faculty Publications

Several machine learning (ML) and deep learning (DL) methods have been used to predict the presence of species in classification problems. Another set of methods, called reinforcement learning (RL), has been used in training agents to perform various tasks, but not in predicting species distribution. Culex pipiens (Diptera: Culicidae), commonly known as the common house mosquito, is a globally distributed species prevalent in temperate and subtropical regions. They serve as a primary vector for West Nile Virus (WNV), a mosquito-borne pathogen that affects humans and other animals. The study objective is to compare the performance of logistic regression, random forest …


Effect Of Chronic Heat Stress On Duodenal Epithelial Barrier Integrity In Low- And High-Water-Efficient Broiler Chickens, Lulu Liu, Elizabeth S. Greene, Brooklee Roach, Sara Orlowski, Sami Dridi Nov 2025

Effect Of Chronic Heat Stress On Duodenal Epithelial Barrier Integrity In Low- And High-Water-Efficient Broiler Chickens, Lulu Liu, Elizabeth S. Greene, Brooklee Roach, Sara Orlowski, Sami Dridi

Poultry Science Faculty Publications and Presentations

Heat stress (HS) has long posed a significant challenge to the poultry industry due to its adverse effects, such as depressed feed intake, decreased growth performance, and increased water consumption. Water efficiency (WE, conversion of water intake into body weight gain), although often neglected, is a key economic and production trait that is significantly affected by HS. Recently, we selected two broiler lines for high WE (HWE) and low WE (LWE) and showed a differential hypothalamic expression of genes involved in water homeostasis regulation. As the gut also plays a significant role in water absorption, the present study aimed to …


Divine Intervention: The Effects Of Repairing Attachment Insecurities With God On Ptsd Symptomology In Adult Survivors Of Childhood Trauma, Erica M. Duckworth Nov 2025

Divine Intervention: The Effects Of Repairing Attachment Insecurities With God On Ptsd Symptomology In Adult Survivors Of Childhood Trauma, Erica M. Duckworth

Doctoral Dissertations and Projects

Childhood trauma occurs when an individual under the age of 18 survives a perceived life-threatening event. To circumvent future danger, numerous developmental changes occur in response to fear, manifesting in a multitude of symptoms. A culmination of symptoms results in Posttraumatic Stress Disorder (PTSD), a debilitating condition that arises from the hypervigilance of the brain and body to environmental stimuli. A recurring state of fear can lead to isolation, negatively affecting social interactions. Expectations of relationships, also known as attachment styles, reflect the bonds created between a child and a parent or caregiver. The quality of this foundational relationship can …


Fire, Covenant, Redemption: Biblical Fire Imagery And Covenant In The Bible, Tony O'Neal Hinton Nov 2025

Fire, Covenant, Redemption: Biblical Fire Imagery And Covenant In The Bible, Tony O'Neal Hinton

Doctoral Dissertations and Projects

Understanding biblical signs and symbolism is essential for recognizing how God communicated and interacted with both the original people of the Bible and the modern church. A lack of this knowledge can often lead to misinterpretation of Scripture or the adoption of a false perception when the original context is neglected. From Genesis to Revelation, signs and symbols typically convey either literal or metaphorical meanings. Numerous passages throughout the Bible demonstrate that God used fire as a tool for various purposes. In fact, the King James Version records the term “fire” over 500 times, underscoring its prominence throughout Scripture. Fire …


Exploring Student Perceptions Of Higher-Education Social Media Presence: A Qualitative Descriptive Study Through The Lens Of The Theory Of Interactive Media Effects, Bobby Mikel Nov 2025

Exploring Student Perceptions Of Higher-Education Social Media Presence: A Qualitative Descriptive Study Through The Lens Of The Theory Of Interactive Media Effects, Bobby Mikel

Doctoral Dissertations and Projects

As higher-education institutions (HEIs) compete for prospective students in an increasingly saturated digital environment, effective communication on social media has become both essential and challenging. Guided by the cybernetic communication tradition and the theory of interactive media effects (TIME), this qualitative descriptive study explored how students perceived and engaged with social media content produced by HEIs. The study utilized a qualitative survey to explore students’ perceptions of social media content produced by an HEI in the southeastern United States. Additionally, a content analysis of social media posts was conducted to examine how the HEI engages with students. Findings revealed that …


Enhancing Spiritual Care In Medical Missions Through A Contextual Apologetic Workshop, Jacob G. Caraotta Nov 2025

Enhancing Spiritual Care In Medical Missions Through A Contextual Apologetic Workshop, Jacob G. Caraotta

Doctoral Dissertations and Projects

There is a lack of resources and a gap in the literature for training prayer teams for medical mission endeavors. The Contextual Apologetic Workshop, an intervention project, was designed to fill the gap in the literature by training participants in prayer, evangelism, and apologetics. It utilized the Contextual Apologetic System, a framework built around the Contextual Triad, which includes the cultural context, setting, and endemic religions that inform outreach dynamics and preparation. The cultural context identifies if the population is high- or low-context, and includes the subcultures. The setting refers to outreach types, such as medical missions or construction projects. …


A Causal-Comparative Study Of Teachers’ Growth Mindsets In Low, Middle, And High Socioeconomic Schools, Molly Bettencourt-Courtright Nov 2025

A Causal-Comparative Study Of Teachers’ Growth Mindsets In Low, Middle, And High Socioeconomic Schools, Molly Bettencourt-Courtright

Doctoral Dissertations and Projects

The purpose of this quantitative, causal-comparative study was to determine if a significant difference exists among teachers’ growth mindsets among those teachers employed at low, middle, or high socioeconomic status schools. This study is important because teachers’ growth mindsets have an impact on students’ academic achievement through factors such as motivation and self-efficacy. Research has demonstrated the correlation between belonging to a low socioeconomic status and poor academic achievement or learning. Therefore, this study adds to the literature regarding the effects of teachers’ growth mindset by examining the differences in mindset among teachers employed at low, middle, and high socioeconomic …


Design, Optimization, And Development Of Ripk1 Degraders With Improved Pharmacokinetic And Pharmacodynamic Properties, Dong Lu, Xin Yu, Hanfeng Lin, Ran Cheng, Bin Yang, Min Zhang, Jingjing Chen, Feng Li, Xiaoli Qi, Jin Wang Nov 2025

Design, Optimization, And Development Of Ripk1 Degraders With Improved Pharmacokinetic And Pharmacodynamic Properties, Dong Lu, Xin Yu, Hanfeng Lin, Ran Cheng, Bin Yang, Min Zhang, Jingjing Chen, Feng Li, Xiaoli Qi, Jin Wang

Faculty, Staff and Students Publications

Pharmacological degradation of receptor-interacting protein kinase 1 (RIPK1) offers a compelling therapeutic strategy to overcome its scaffolding role in tumor resistance and to enhance the efficacy of immune checkpoint blockade (ICB) therapies. In this study, we report the discovery of a novel RIPK1 degrader, LD5097(24b), developed through systematic optimization of its precursor compound, LD4172—specifically refining the linker, RIPK1 warhead exit vector, and VHL ligand components. LD5097(24b) exhibits potent and selective RIPK1 degradation, triggering rapid and efficient downregulation of RIPK1 and significantly enhancing TNFα-mediated apoptosis in Jurkat cells. Compared to LD4172, LD5097(24b) demonstrates markedly improved metabolic stability and pharmacokinetic properties. In …


Genetic And Embryonic Transcriptome Analyses Reveal The Molecular And Developmental Basis Of Mayer-Rokitansky-Küster-Hauser Syndrome, Na Chen, Xi Cheng, Sen Zhao, Hengqiang Zhao, Chenglu Qin, Yaru Zhang, Xijuan Lin, Qing Li, Yuan Wang, Jia Kang, Jing Yu, Jianbin Guo, Qianqian Gao, Jiali Duan, Yuchen Niu, Jianzhong Su, Zhihong Wu, Terry Jianguo Zhang, Wanlu Liu, Pengfei Liu, Shan Deng, Nan Wu, Lan Zhu Nov 2025

Genetic And Embryonic Transcriptome Analyses Reveal The Molecular And Developmental Basis Of Mayer-Rokitansky-Küster-Hauser Syndrome, Na Chen, Xi Cheng, Sen Zhao, Hengqiang Zhao, Chenglu Qin, Yaru Zhang, Xijuan Lin, Qing Li, Yuan Wang, Jia Kang, Jing Yu, Jianbin Guo, Qianqian Gao, Jiali Duan, Yuchen Niu, Jianzhong Su, Zhihong Wu, Terry Jianguo Zhang, Wanlu Liu, Pengfei Liu, Shan Deng, Nan Wu, Lan Zhu

Faculty, Staff and Students Publications

Background: Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) is characterised by aplasia of the uterus, cervix and upper part of the vagina. The genetic aetiology remains incompletely understood.

Methods: We performed gene-level and gene set-level burden analyses based on exome sequencing/genome sequencing data from 727 probands with MRKHS and 2504 female control individuals. Single-cell RNA sequencing (scRNA-seq) was performed on human and mouse embryonic metanephros at different developmental stages. Genetic and transcriptomic data were integrated to prioritise suboptimal genetic signals, identify relevant cell types and determine key developmental stages. Potential digenic inheritance was assessed and prioritised using coexpression patterns from scRNA-seq data.

Results: We …