Digital Commons Network^™

The Power Of Pets: Navigating Infancy, Early Development, And Eventual Loss/ Exploring The Mutual Human-Animal Bond Through Children’S Board And Picture Books With Critical Anthropomorphism, Mary Teresa Woodcock

Children's Book Writing and Illustrating (MFA) Theses

Pets are powerful elements of picture books. Alongside our animal companions, we navigate infancy, early childhood and adulthood, and better understand our relationships and life itself. Critical anthropomorphism allows us to represent our relationship to our animal companions ethically in the written and illustrated text. This paper acknowledges an array of primary and scholarly texts about animals and their roles in human experience as a foundation for my three book projects “A Colorful Night for Cat,” “Grandma, Sam, and Me,” and “Tired Old Socks.” I work to portray animal companions authentically, showing how both humans and animal companions benefit from …

A Metadata Analysis Of Unionid Mussels Of The Greenup Pool Of The Ohio River Using Occupancy Modeling And Species Area Curves, Tyler Mitchell Annarino

Theses, Dissertations and Capstones

Although North America contains the largest diversity of freshwater mussels in the world, only ~24% of species in the United States and Canada have stable populations. This group provides unique hurdles for surveying, and current unionid survey protocols include neither longitudinal studies nor randomization of sites. This project conducts a metadata analysis of freshwater mussels in the Greenup Pool of the Ohio River (GPOR) to answer three questions: 1. Does a combination of longitudinal scope, randomization of sites, and historic methodology of surveying result in useful occupancy/detection models (ODMs) of unionids in large streams at the family level? 2. Does …

Investigating The Potential Of Broccoli Seed Extract To Attenuate Morphine Tolerance, Atharv Ashwin Battu, Minho Kang, Hamid Akbarali

Pharmacology and Toxicology Publications

Opioids remain one of the most effective treatment strategies for managing severe and persistent pain. However, its long-term use leads to pharmacological tolerance, requiring progressively higher doses to achieve analgesia. This dose escalation increases the risk of life-threatening side effects and dependence, underscoring the urgent need for safe adjuncts to preserve opioid efficacy. Emerging evidence suggests that morphine tolerance is linked to intestinal inflammation and disruption of gut barrier integrity. Broccoli Seed Extract (BSE), rich in the bioactive compound sulforaphane, exhibits antioxidant and anti-inflammatory properties that may protect against these effects. We hypothesized that BSE could prevent the development of …

Layer Industry Update: Nutrition Associated With Changes In Production Systems, Kenneth E. Anderson, Ishab Poudel

Proceedings of the Arkansas Nutrition Conference

This is not a hardcore research presentation but rather an overview of three North Carolina Layer Performance and Management Tests. I used the 39th, 40th, and 41st Layer Test Reports that cover the years 2013 through 2025. The proceedings cover white and brown egg strains as groups and the cage and cage-free production environments. Over all three of these tests the production environments were the same and met UEP Cage standards and the Humane Farm Animal Care cage-free standards. There are papers outlining the changes in more detail with all the statistics. This is an overview of visual trends in …

Field Experience And Production Challenges In Australia And New Zealand, Nick Rodgers

Proceedings of the Arkansas Nutrition Conference

Variability management represents the primary technical challenge facing the Australian and New Zealand (ANZ) broiler industry's vertically integrated operations. This analysis examines systematic approaches to controlling seasonal performance fluctuations, raw material quality variations, emerging disease pressures, and evolving welfare demands. Key variability sources include climatic extremes, season to season raw material quality and nutrient value variability and intermittent [mostly enteric] disease challenges, particularly in no antibiotics ever (NAE) production systems. Solutions require a scientific, data-driven approach with insights from field experience for causation identification and a collaborative approach within business functional units, and across industry collaborators such as suppliers and …

Birth And Rebirth: The Fish In Mesoamerican Art And Its Implication On Stela 5, Izapa, Chiapas, Mexico, Diane E. Wirth

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

A revealing analysis of fish iconography in Mesoamerica, in relation to the ancestral couple on Stela 5, Izapa, Chiapas, Mexico, holds an unforeseen element that may reveal a key to the Tree of Life referred to in the Book of Mormon. This key is supported by Mesoamerican, Hebrew, and Egyptian traditions.

Brain-Targeting Polymeric Micelles For Intranasal Delivery Of Rapamycin In Alzheimer’S Disease Treatment, Vrashabh V. Sugandhi

Theses and Dissertations

Alzheimer’s disease (AD) is a long-term neurological disorder associated with neuroinflammation and amyloid-beta (Aβ) aggregation, which leads to a decline in cognitive and behavioral changes. Rapamycin (Rapa) is an immunosuppressive drug effective in preventing organ rejection after a kidney transplant. In the last few years, orally delivered Rapa has emerged as a potential candidate for improving cognitive function in patients with AD. However, it is evident that long-term oral treatment of Rapa causes systemic toxicity, and although controversial, it may even trigger the aggregation of Aβ deposition. This study investigated the therapeutic potential of intranasally delivered brain-targeting polymeric micelles carrying …

2025-2026 Factbook, Tennessee. General Assembly

Factbook

This Fact Book provides an overview of the state's budget for the fiscal year.

Establishment And Characterization Of Vincristine-Resistant S1 Colon Cancer Cells, Harsh Patel

Theses and Dissertations

Colorectal cancer (CRC) remains one of the most common causes of cancer-related mortality worldwide. Vincristine is frequently used to treat CRC, although the specific pathways leading to acquired resistance are still not fully understood. In this study, we established two novel vincristine-resistant human colon cell lines (S1/V1 and S1/V4) to explore the mechanisms underlying vincristine resistance, with a particular emphasis on the overexpression of ATP-binding cassette (ABC) transporters. The S1/V1 and S1/V4 sublines were derived by continuously exposing human S1 colon cancer cells to vincristine. An MTT cytotoxicity assay revealed that S1/V1 cells exhibit about 39-fold greater resistance to vincristine …

Gastronomy At The Heart Of Communication: A Locus Of Human Conviviality, Victoria M. O’Keefe

Theses and Dissertations

The significance of food over time is central to humanity and can aid in making people humane in a myriad of ways. This study seeks to (a) define the role of food in communication across sectors of global society and in the media realm (b) by analyzing a data set of all food related publications of the flagship magazine of UNESCO, The Courier, (c) through ethnographic study and inductive coding, I draw themes and trends that alter food communication from a multinational organization and pass the content through a theoretical lens and Large Language Model tool, to (d) illuminate implications …

Propelling Whole-Cell Biosensor Creation By Leveraging Gene Fusion To Assemble Synthetic Functional Transcription Factors For The Detection Of Biomarkers, Samuel J. Verzino

Theses and Dissertations

Biosensors are analytical devices that leverage biological modules for the detection of molecules of interest. As customizable tools designed to aid in a wide array of diagnostics, these instruments are rapidly advancing the field of synthetic biology. While varied in their construction and purpose, biosensors are ultimately concerned with converting a physicochemical stimulus into a detectable signal. Among the many existing variants, whole-cell biosensors (WCBs) stand out due to their versatility and engineering potential. WCBs are a type of biosensor in which a physiologically active cell sustains an array of biomolecular elements - receptors, transporters, regulators, etc. - capable of …

Investigation Of The Binding Mechanisms Between Naphthenic Acids And Humic Acid Using Raman Spectroscopy And Computational Modeling, Jaelyn N. Palmer

Theses and Dissertations

The oil sand regions in Alberta, Canada have proven to be costly to the environment despite its economic benefits. The toxins produced during oil processing are sent to tailing ponds to be recycled, though often leaking into nearby waterways and soil. Naphthenic acids, NAs, are one of the most common toxins produced and have shown to be toxic to aquatic life, animals, and humans. As there is dissolved organic matter in tailing ponds and surrounding environments, tailing ponds often lead to NAs coming in contact with organic material. Humic acid, HA, is a major soil component that has been suspected …

Qualitative Analysis Via Network Models Of Human Dynamin-1 Throughout Gtp Hydrolysis, Kevin Brian Schulman

Theses and Dissertations

This thesis aims to elucidate the molecular mechanisms by which nucleotide binding dictates the intrinsic dynamics and to understand the functional conformational changes of Human Dynamin-1 during the GTP hydrolysis cycle through the use of Elastic Network Models (ENM). A comprehensive understanding of this process is crucial given dynamin's role in clathrin-mediated endocytosis (CME). The research utilized both experimentally derived crystal structures and AlphaFold-predicted structures of dynamin, specifically examining the GTPase and Bundle Signaling Element (BSE) domains across nucleotide-free, GTP-bound, GDP-bound, and transition states. The essential features of the research methodology involved a multi-scale computational approach. Qualitative analyses were performed …

Recognizing Speculative Literature: Conceiving Identity In The Archives Of Enslavement, Gabriella Greco

Theses and Dissertations

One of the key problems of the archive of enslavement, borne out of the violent erasure of enslaved identities, is the struggle to reconstruct and honor those lost identities. Recognizing Speculative Literature: Conceiving Identity in the Archives of Enslavement investigates postcolonial archival processes and the resulting documents to identify a spectrum of speculative literary genres that can be used to supplement traumatic archival erasures, often of female voices and identities, to further understand the power dynamics. To clarify, I use the term ‘speculative literature’ here to refer to a mode of literature that relies on the few fragments that may …

Sustainability Risk In Guyana’S Oil Sector: An Analytical Framework For Balancing Environmental And Economic Impacts, Kayla B. Moonsammy

Theses and Dissertations

This study investigates the sustainability risks posed by Guyana’s rapidly expanding oil sector, with particular focus on balancing economic benefits against environmental vulnerabilities. The primary aim is to develop a Sustainability Risk Index (SRI) that captures the multidimensional impacts of offshore oil development using an integrated data-driven framework. Specifically, this thesis examines how emissions, biodiversity loss, oil spill exposure, economic volatility, and social development indicators interact to influence sustainability outcomes in the context of Guyana’s transition into a major petroleum-producing nation. The research does not involve human participants; instead, it draws on publicly available datasets collected from 2015 to 2024. …

Winter 2025, Augustana College, Rock Island Illinois

Augustana Magazine

No abstract provided.

This Is Gospel; Seven Stories And A Nonfiction Braid (Bacc To Writing, Writing To Bacc; A Short Story Collection), Zena Williams

Theses & ETDs

My thesis for spring of 2025 is a collection of seven short stories and one nonfiction piece. These are pieces I have created over my time here at New College. Each has been redrafted at least three times, and it has been a long process to build this collection that I am so proud of. I hope you enjoy it, but first maybe some context. Coming soon! No clue if this is right or not.

Practicing Intercultural Discipleship, Akali Nya

Academic Books

No abstract provided.

The Meaning Of Life, In Michigan: Mercy From Life Sentences Under The State Constitution, Molly Bernstein, David Shapiro

JCLC Online

Properly understood, the “cruel or unusual” punishment clause of the Michigan Constitution grants every person sentenced to life in prison a meaningful right to obtain release through rehabilitation. Today, however, Michigan has among the nation’s largest populations of people serving both formal and de facto life sentences without any meaningful possibility of release.

In 1850, Michigan revised its state constitution to prohibit “cruel or unusual punishment,” creating a contrast with the conjunctive “cruel and unusual punishments” clause of the federal Eighth Amendment. This disjunctive prohibition, which subsequent Michigan constitutional conventions retained, prohibits both “cruel” sentences and “unusual” sentences. We argue …

For Official Violence, The Devil's In The Dehumanizing Details, Rachel Kincaid

JCLC Online

In Excessive Force in Prison, Professor Sharon Dolovich tackles the shortcomings of the Eighth Amendment’s cruel and unusual punishment doctrine to govern uses of official violence against prisoners. She argues that law enforcement officers owe a duty of care and protection to incarcerated people, but that duty of care and protection is undermined by the dehumanization and demonization of prisoners. Professor Dolovich thus advocates for shifting the doctrinal standard for excessive force under the Eighth Amendment to one based on objective reasonableness, paired with jury instructions explicitly reminding jurors of incarcerated victims’ humanity. To counteract the vagaries of such an …

A History Of Individuation: Aristotle, Jung, Simondon And The Vital Impulse, Sam Gould

International Journal of Transpersonal Studies Advance Publication Archive

This paper theoretically situates transformation as a biophysiological process specific to information transfer in and throughout a multicellular organism, conceptualized as the epigenesis, morphogenesis, and formation of the self in the unfolding process of individuation. The self will be ascribed, not merely as the Jungian definition of something to be realized through individuation, but rather, as a twofold operation: (a) As a conjunction within the process of individuation that extends into, as part of, the possible future process of individuation; to account for this phase in the operation of the unfolding of the self, the paper refers to Gilbert Simondon’s …

The Efficacy And Safety Of Baricitinib In The Treatment Of Alopecia Areata, Ireny Sharkawy

The PA Department Journal of Medical Science

Introduction: Alopecia Areata (AA) is an autoimmune disorder that causes inflammatory circular, coin-shaped patches of hair loss on the scalp and other body parts. Baricitinib, a Janus Kinase (JAK) inhibitor, is a new medication approved for the treatment of AA. This review paper evaluates the effectiveness and safety of baricitinib in treating hair loss in patients with alopecia areata compared to no intervention.

Methods: The efficacy and safety of baricitinib in treating AA patients were evaluated by utilizing five (5) clinical articles, including randomized controlled trials, systematic reviews, and meta-analyses, sourced from PubMed.

Results: Baricitinib JAK inhibitor was shown …

Semaglutide Vs Liraglutide For Weight Loss In Adults With Obesity, Orian Bar

The PA Department Journal of Medical Science

Introduction: Obesity is a growing chronic condition worldwide with limited effective and safe treatment options. Semaglutide and liraglutide are two GLP-1a medications with encouraging outcomes for the treatment of obesity. The purpose of this paper is to compare semaglutide to liraglutide for weight loss and obesity

Methods: Pubmed was searched for randomized controlled trials, systematic reviews, and meta- analyses from 2019 to 2024 to assess efficacy of semaglutide and liraglutide. Five articles were selected for clinical review.

Results: In 4 out of the 5 studies there was a greater reduction in weight in patients receiving semaglutide compared to liraglutide. Statistically …

2025 Program, Belmont University

Humanities Symposium Programs

No abstract provided.

Looking For Difference: Using Declamation And Controversial Images To Frame Civic Engagement, Adam J. Gaffey

Communication Studies Faculty Works

Adam Gaffey's chapter titled "Looking for Difference: Using Declamation and Contro versial Images to Frame Civic Engagement" (pp. 177-193) is in the book Encouraging College Students' Democratic Engagement in an Era of Political Polarization, edited by Angela M. McGowan-Kirsch, Lexington Books, 2025.

The Sovereign Of Serpent, Anthony Morris

Allusions

No abstract provided.

Maginot, Tom Thompson

Allusions

No abstract provided.

Dandelions In The Breeze, Destiny Dunham

Allusions

No abstract provided.

An Apple, A Wager, A Whisper, Briarlynn Hawkins

Allusions

No abstract provided.

Shelter, Kerrigan Hargis

Allusions

No abstract provided.