Digital Commons Network^™

Early Blood Pressure Targets In Acute Spinal Cord Injury: A Randomized Clinical Trial, Ruba Sajdeya, N. David Yanez, Michael Kampp, Michael D. Goodman, David Zonies, Brandon Togioka, Andrew Nunn, Robert D. Winfield, Niels D. Martin, Anirudh Kohli, Toan T. Huynh, David O. Okonkwo, Roy A. Poblete, Emily J. Gilmore, Randall M. Chesnut, Aaron E. Bunnell, Tetsu Ohnuma, Mona Hashemaghaie, Miriam M. Treggiari

Department of Surgery Faculty Papers

IMPORTANCE: Early blood pressure management is central to neurologic resuscitation of spinal cord injury; however, the role of augmented blood pressure is unclear.

OBJECTIVE: To compare the efficacy and safety of augmented vs conventional blood pressure on 6-month neurologic outcomes after acute spinal cord injury.

DESIGN, SETTING, AND PARTICIPANTS: This multicenter randomized clinical trial took place from October 3, 2017, to July 26, 2023, and assessed patients 18 years or older with spinal cord injury followed up for 6 months at 13 large US trauma centers.

INTERVENTIONS: Patients were equally randomized to augmented (>85-90 mm Hg) or conventional ( …

Framework For Assessing Sustainability In Industry 4.0: Supply Chain Optimization, Manufacturing Processes, And Energy Consumption Reduction, Mohamed Abouhawwash, Nebojsa Bacanin

Sustainable Machine Intelligence Journal

Decision making has uncertainty problems in evaluation process, so to overcome uncertainty existing fuzzy decision-making approaches, the neutrosophic set is used to solve incomplete data. Interval valued neutrosophic numbers (IVNNs) are used in this study to solve uncertainty problems. The IVNNs are used with the multi-criteria decision making (MCDM) methods. MCDM method is used to deal with different criteria and alternatives. This study proposes an MCDM methodology for assessment sustainability in industry 4.0. Twenty cases and ten alternatives are used in this study. The criteria weights are computed using the average method. The alternatives are ranked using the ARAS method. …

Differential Effects Of Macrophage Subtype-Specific Cytokines On Fibroblast Proliferation And Endothelial Cell Function In Co-Culture System, Phillip Mcclellan, Thomas R. Wong, Sara Hijaz, David R. Fletcher, Ozan Akkus, Tracey L. Bonfield, James M. Anderson, Adonis Hijaz

Faculty Scholarship

Macrophages are involved in several critical activities associated with tissue repair and regeneration. Current approaches in regenerative medicine are focusing on leveraging the innate immune response to accelerate tissue regeneration and improve long-term healing outcomes. Of particular interest in this regard are the currently known, four main M2 macrophage subtypes: M2interleukin (IL)-4,IL-13, M2IC, M2IL-10, M2non-selective adenosine receptor agonists (NECA) (M2IL-4,IL-13 → M2(NECA). In this study, rat bone marrow-derived macrophages (M₀) were polarized to each of the four subtypes M2IL-4,IL-13 → M2NECA and cultured for 72 h in vitro. Luminex assay results highlighted increased production of tissue inhibitor of metalloproteinases-1 (TIMP-1) …

Decolonizing Colombian Foreign-Language Classroom Assessments: A Meaningful Framework, Patricia Grillet Rodriguez

Journal of Comparative & International Higher Education

In Colombia, foreign-language evaluation validity appears to be mainly related to the analysis of instruments, leaving aside students’ characteristics, affective schemata and expectations. Drawing from critical pedagogy, this study aimed at raising authenticity and meaningfulness in the development of valid foreign-language assessments in a higher education classroom. Framed in the sociocultural perspective, the teacher/researcher and her students obtained substantial gains by adapting a syllabus and evaluation system to better respond to the needs of their context. It was a collaborative process that implied contextualizing contents, establishing a concept of language ability, and including students’ voices in the design of assessments, …

The Cowl - V. 89 N. 1 - September 18, 2025

The Cowl

The Cowl - student newspaper of Providence College. Vol. 89 No. 1 - September 18, 2025. 20 pages.

Arbuscular Mycorrhizal Fungi As Key Drivers Of Plant Resilience: Mechanisms Of Stress Adaptation In Saline Environments, Rayna Elizabeth Koberstein

Dissertations and Theses

Arbuscular mycorrhizal fungi (AMF) play a critical role in mediating plant responses to environmental stress, yet their ecological significance in saline wetland restoration remains underexplored. This greenhouse experiment investigated the effects of salinity, root-zone barrier type (solid, mesh, none), and neighboring species identity on AMF colonization and physiological responses in three native estuarine plants: Carex densa, Juncus patens, and Scirpus microcarpus. Results demonstrated species-specific physiological responses to salinity, with Juncus patens showing greater resilience in maintaining photosynthetic efficiency (Fv/Fm) and percent cover at higher salinity levels, while Scirpus microcarpus exhibited a significant decline. Mesh barriers, which permitted …

Semilunar Valve Replacement With A Telescoping Arterial Trunk Valve, Edo Bedzra, Herra Javed, James E. O'Brien, Taufiek Konrad Rajab

Manuscripts, Articles, Book Chapters and Other Papers

A bicuspid aortic valve, from autologous tissue, with growth potential can be constructed using the simple, and reproducible telescoping arterial trunk technique.

Montana Kaimin, September 18, 2025, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Bioresources And Bioproducts: A New Open Access Journal, Ronald C. Sims

Biological Engineering Faculty Publications

Greetings to the bioresource and bioproducts community! I will serve as the Editor-in-Chief to collaborate with you as we promote the aims and scope of this new MDPI journal [1], with the help of its distinguished Editorial Board, by publishing Special Issues, Topics, Topical Collections, and Editorials, and by providing high-impact scholarship through the outstanding published work of each of our contributors.

Spartan Daily, September 18, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 12

Ws-Fall: Fall Detection Attention-Based Approach Using Wifi And Inertial Data Modalities, Alaa Elmor, Bilal Arain

Sustainable Machine Intelligence Journal

According to the World Health Organization, 37 million falls occur every year which leads to sever injuries that require medical intervention. In addition, more than 600,000 people end up dying due to falls making them the second cause of accidental injury fatalities worldwide. Specifically, the elderly are more prone to fatal falls. Therefore, fall detection systems are needed to allow medical professionals to intervene in such cases. Various wearable and non-contact fall detection devices have been developed recently. Since non-contact Wi-Fi-based methods are widely available and non-intrusive, they are gaining popularity. In this paper, we propose a state-of-the-art fall detection …

Mymoney: A Program That Leverages Digital And Artificial Intelligence Tools For Improving The Financial Wellbeing Of Hispanic Families, Luisa Blanco, Kamila Campos, Jessica Gonzalez, Jorge Macias

School of Public Policy Working Papers

Abstract: Our Community-Based Digital Intervention (CBDI) MyMoney was designed to meet the informational needs and promote behavioral change among Hispanic adults. We leverage Digital and Artificial Intelligence (DAI) tools to provide participants access to content that is linguistically and culturally tailored and structured to be delivered in short, accessible modules. MyMoney program provided an introductory experience to financial education with a mobilephone based approach, offering a four-week experience for improving money management skills. We conducted an extensive quantitative and qualitative data analysis of participants’ and stakeholders’ program experience and perspectives, which provides important insights for the design, evaluation, and implementation …

September 18, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Uav-Based Transport Management For Smart Cities Using Machine Learning, Sweekruthi Balivada, Jerry Gao, Yuting Sha, Manisha Lagisetty, Damini Vichare

Faculty Research, Scholarly, and Creative Activity

Highlights: What are the main findings? A smart transport management system based on UAV data integrating advanced machine learning and deep learning techniques is proposed to enhance road anomaly detection and severity classification. The system employs a comprehensive multi-stage framework, integrating a high-precision obstacle detection model, six specialized severity classification models, and an aggregation model to deliver accurate anomaly assessment, enabling strategic, data-driven road maintenance and enhanced transportation safety. What is the implication of the main finding? A scalable and efficient solution is proposed to enhance road safety and optimize transportation management through intelligent anomaly detection and severity assessment. This …

Kenyon Collegian - September 18, 2025

The Kenyon Collegian

No abstract provided.

Gc-Ms-Based Metabolomics For Understanding The Metabolite Profile Of Mopane Worm (Gonimbrasia Belina) And Sorghum (Sorghum Bicolor L), Mpho Sebabiki Maleke, Tumisi Beiri Jeremiah Molelekoa, Jonathan Wilkin, Xi Feng, Moira Ledbetter, Oluwafemi Ayodeji Adebo

Faculty Research, Scholarly, and Creative Activity

Edible insects are nutritious, having high levels of protein, essential amino acids, healthy fats, vitamins, and minerals. In areas where sorghum is a primary crop, mixing this gluten-free grain with protein-rich insect powder provides a novel approach to making nutrient-rich products. Understanding the sorghum and mopane worm flours' metabolomic changes during bioprocessing can however, enhance their nutritional value and food safety. The research investigated metabolite compounds that are found in raw and processed (fermented, malted (sorghum), and ultrasonicated) mopane worms and sorghum. In the study, sorghum grains were traditionally fermented and malted at 35°C for 48 h and ultrasonicated for …

Ai Test Modeling For Computer Vision System—A Case Study, Jerry Gao, Radhika Agarwal

Faculty Research, Scholarly, and Creative Activity

This paper presents an intelligent AI test modeling framework for computer vision systems, focused on image-based systems. A three-dimensional (3D) model using decision tables enables model-based function testing, automated test data generation, and comprehensive coverage analysis. A case study using the Seek by iNaturalist application demonstrates the framework’s applicability to real-world CV tasks. It effectively identifies species and non-species under varying image conditions such as distance, blur, brightness, and grayscale. This study contributes a structured methodology that advances our academic understanding of model-based CV testing while offering practical tools for improving the robustness and reliability of AI-driven vision applications.

Gaming The Endowment Tax, Christopher J. Ryan Jr., Christopher R. Marsicano, Ann F. Bernhardt, Rylie C. Martin

Florida Tax Review

The 2017 law known as the Tax Cuts and Jobs Act (TCJA) enacted a tax on private, non-profit college and university endowments for the first time. Institutions with at least 500 tuition-paying students and endowments of $500,000 or greater per student now have to pay a 1.4% tax on their endowments. But like all taxpayers, colleges and universities may be tax averse or seek reductions in their tax burdens. That is, colleges and universities may try to avoid the tax through taking action to ensure they do not meet the threshold. Such actions include increasing the size of their student …

Stream Temperature Responses To Summer Urban Rain Events Along The Savannah River, Joseph E. Wermter, Vivian L. Turner, Max K. Appelbaum, James M. Shepherd, Jacob Z. Lott

Journal of South Carolina Water Resources

The hydrological urban heat island (HUHI) is a recent facet of the urban heat island (UHI), describing thermal enhancement of bodies of water in response to urbanization. Although the forefront of this work has been studied for large Metropolitan areas, this effect on developing cities is currently unknown. To locally measure and quantify HUHI effects in a developing city, we utilized Multi-Radar Multi Sensor (MRMS) radar-derived rainfall data to estimate rainfall in the Augusta Metropolitan Area (AMA) and the Savannah Metropolitan Area (SMA), two developing communities adjacent to the Savannah River. We analyzed mean temperature trends of two stream gauges …

Nanovesicles Derived From Protocorm-Like Bodies Of Dendrobium Officinal Enhance Corneal Epithelial Repair And Reduce Inflammation In Dry Eye Disease Models, Bao Yuqing, Peng Chengyu, Zhang Fenglei, Zheng Yuqiang, Zhang Mingqi, He Wei

Journal of Food and Drug Analysis

Plant-derived nanovesicles (PDNVs) offer a promising, biocompatible therapeutic platform. In this study, we isolatednanovesicles from protocorm-like bodies of Dendrobium officinale (PLBs-NVs) and evaluated their efficacy in dry eyedisease (DED) models. PLBs-NVs protected human corneal epithelial cells against hyperosmotic stress, supportedwound repair, and inhibited inflammation in vitro. In a desiccating stress-induced DED mouse model, topical PLBs-NVstreatment significantly restored tear secretion, reduced corneal epithelial damage, and lowered levels of proinflammatorycytokines. These results suggest that PLBs-NVs are a safe, natural, and effective therapeutic strategy for DED, sup-porting their potential for future clinical translation in ocular surface disorders.

Protective Effects Of Jujube Seed Extract Against Oxidative Stress In Ht22 Cells And Its Sleep-Promoting Action Through Gabaergic Receptors, Seok Hyun Chung, Hyeongyeong Kim, Singeun Kim, Pan-Young Jeong, Hyowon Lee

Journal of Food and Drug Analysis

Jujube seed extract (JSE), rich in polyphenols and flavonoids, exhibits neuroprotective and sleep-enhancing properties.In vitro, JSE protected HT22 cells against oxidative stress by activating the Nrf2/HO-1 pathway and upregulatingantioxidant enzymes. In vivo, JSE increased non-REM sleep and delta wave activity in pentobarbital- and caffeine-induced sleep models. Spinosin contributed to these effects. Long-term JSE administration upregulated GABAA, GABAB, and 5-HT1A receptors in brain tissue. These findings suggest that JSE offers dual benefits in mitigating oxidativestress and promoting sleep through antioxidant defense and neurotransmitter modulation, supporting its potential as a natural therapeutic agent.

Yi-Qi-Xuan-Fei Formula Ameliorate Chronic Obstructive Pulmonary Disease By Remodeling Lung And Intestinal Florase In Rat Models, Si-Si Han, Li-Yun Song, Peng-Tao Liang, Yin-Ying Wang, Yi Ying, Li Li, Jia-Li Yuan, Zhong-Shan Yang

Journal of Food and Drug Analysis

Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease characterized by various pathologicallesions and an imbalance in the microflora. The Yi-Qi-Xuan-Fei Formula (YQXF) is a clinically effective formula withpharmacological potential to delay the progression of COPD. This study aims to explore the relationship between thetherapeutic mechanism of YQXF and the microflora in COPD. Our study found that YQXF reduces inflammatory injuryand inflammatory cell infiltration in lung tissue, repairs the intestinal mucosal barrier, and enhances immune function.Additionally, YQXF regulates the pulmonary and intestinal flora by increasing the abundance of Alloprevotella, Rose-buria, Oscillibacter, and Lactobacillus, while reducing the abundance of …

Precision Nanomedicine For Anxiety: Challenges, Opportunities, And Future Directions In Targeted Drug Delivery, Sehrabpreet Singh, Amanpreet Singh, Shruti Chittu, Shailesh Sharma

Journal of Food and Drug Analysis

Nanoparticle-based drug delivery system represents one of the challenging strategies suggested to improve anxietydisorder therapeutic approaches, clinic challenges of delayed action, side effect-free designing and poor patientcompliance. Traditional pharmacological agents can increase drug bioavailability and target specific brain regions,whereas nanoparticle-mediated controlled release offers enhanced precision and sustained action. The others in thisreview concentrate on several kinds of nanoparticle, including lipid-based, polymeric-metallic, and responsive nano-particles, their use in anxiety medication. In addition, emphasis is placed on precision medicine that pertain the delivery of treatment based on an individual's genetic, environmental and lifestyle aspects. Also, it is looked into how artificial intelligence …

The Rhythm Of Decline: Circadian Disruption In Neurodegeneration, Jeewanjot Singh, Devinder Kumar, Jasleen Kaur, Amanpreet Singh

Journal of Food and Drug Analysis

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a multifactorial etiology involving genetic,environmental, and metabolic factors. Among these, circadian rhythm disruption has emerged as a crucial but under-explored contributor to disease progression. The circadian system, regulated by the suprachiasmatic nucleus (SCN),controls essential physiological functions such as the sleep-wake cycle, metabolism, and neuroendocrine signaling.Disruption of this system has been increasingly linked to key pathological features of AD, including amyloid-betaaccumulation, tau hyperphosphorylation, and neuroinflammation. This review critically examines the mechanistic roleof circadian misalignment in AD by analyzing studies on sleep disturbances, SCN degeneration, metabolic dysregu-lation, clock gene polymorphisms (BMAL1, CLOCK, PER, …

Targeted Nanosponge-Based Treatment For Pulmonary Hypertension: A Novel Approach, Jashanpreet Kaur, Gursimran Kaur, Chamanpreet Kaur, Sandeep Kumar

Journal of Food and Drug Analysis

Pulmonary Hypertension (PH) is a progressive and potentially fatal condition marked by high pulmonary arterypressure, resulting in heart failure and reduced oxygenation. Despite advancements in treatments, therapeutic optionsfor PH remain limited, particularly in cases resistant to conventional therapies. In biomedical research, nanotechnologyhas become a potential area of study, presenting novel approaches to drug delivery and tissue targeting. Nanosponges, aclass of nanoparticles with porous structures, have gained attention for their ability to encapsulate therapeutic agents,enhance drug stability, and provide controlled release. Nanosponges can be engineered to deliver vasodilators, anti-inflammatory drugs, and gene therapies directly to the pulmonary vasculature, minimizing systemic side …

In Vivo And In Vitro Perspectives In Parkinson's Disease: Mechanisms And The Role Of Phytomedicine, Jeewanjot Singh, Devinder Kumar

Journal of Food and Drug Analysis

Parkinson's disease (PD) is a progressive neurodegenerative disorder marked by dopaminergic neuronal loss,oxidative stress, neuroinflammation, and a-synuclein aggregation. Despite advances, current treatments only offersymptomatic relief without altering disease progression. This review aims to evaluate the therapeutic potential of plant-derived phytochemicals in PD through evidence from both in vivo and in vitro experimental models. Key findingsindicate that rodent models (e.g., MPTP, rotenone) and neuronal cell lines (e.g., SH-SY5Y) help replicate PD pathologyand mechanistic insights. Phytochemicals such as baicalein, morin, ferulic acid, and bacopa demonstrate neuroprotectiveeffects via antioxidant, anti-inflammatory, and mitochondrial-stabilizing pathways. Nanotechnology and brain orga-noids further improve translational relevance. In conclusion, …

Factors Influencing The Use Of Gis-Enabled Public E-Participation For Municipal Solid Waste Management, Irene Arinaitwe, Agnes Nakakawa, Gilbert Maiga

The African Journal of Information Systems

Due to rapid global population growth and urbanization, approximately two billion metric tons of waste are generated annually. Municipal solid waste management has become a critical function for urban authorities. However, many urban authorities in low- and middle-income economies cannot provide efficient municipal solid waste management services because of suboptimal stakeholder participation in governance processes and inadequate information exchange. Therefore, this study sought to determine factors that influence the implementation of GIS-enabled public e-participation using Enhanced Adaptive Structuration Theory. A descriptive field study was conducted among staff of municipal authorities and residents in Uganda’s Kampala Metropolitan Area. Data were analyzed …

Vml Special - Models, Gundam, Eva

V Music Magazine

No abstract provided.

Vol. 4 Full Issue

V Music Magazine

No abstract provided.

Illegal Corporate Cultures, Elise Bernlohr Maizel

Duke Law Journal

Culture is a powerful force in corporate compliance. Corporate culture shapes how employees behave, dictating whether, when, and how they follow the law. Cases arising out of cultural failures often involve public harm—plane crashes, poisoned rivers, tainted cancer drugs, and collapsed mines. Before these awful outcomes, however, the corporations that caused these harms fostered cultures that permitted the disregard of legal commands and public commitments. Managers disparaged safety regulations. Messages about profits and production drowned out messages about compliance and safety. Yet, there is a gap between all we know about the power of culture and our understanding of corporate …