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Frank Marsh, Jr. V. Attorney General New Jersey

2025 Decisions

USDC for the District of New Jersey

The Effects Of Exposure To Ultraviolet Light On The Activity Of Catalase In Internal And External Tissues Of The Sea Urchin Lytechinus Variegatus, Ellerie C. Heinzmann

Undergraduate Theses

Exposure to ultraviolet radiation (UVR) can have negative impacts on organisms that are exposed to it. The sea urchin Lytechinus variegatus is an organism that resides in shallow waters which can experience exposure to UVR. One negative impact that can occur from UVR is an increase in production of reactive oxygen species (ROS) due to cell stress. In this experiment, two treatments were performed on L. variegatus in the adult state. The first included an exposure to UV-B radiation for 8 hours, and the second was an 8-hour UV-B exposure with temperatures at 30 °C to replicate environmental conditions in …

Volatile Organic Compound (Voc) Sensing Trend Among Novel 2d/3d Materials, Mohammad Shakhawat Hossain

USF Tampa Graduate Theses and Dissertations

Volatile Organic Compounds (VOCs) present significant health risks to both humans and animals. Long term exposure to certain VOCs belonging to certain chemical classes can cause both short- and long-term effects including nausea, damage to the central nervous system, and cancer. VOCs can be found in various everyday products like varnishes, paints, cooking items, cleaning products, nail polishes etc. Because of their ubiquitous nature, health concerns and risks regarding VOC exposure have become even more pressing. In this study, the VOC sensing capabilities and trends of novel 2D, and 3D materials (perovskite, and phthalocyanines) have been explored through electrochemical and …

Green Urban Planning In Tokyo: Managing Natural Spaces For Sustainable Development, Gilberto Mejía Salazar

Japanese Society and Culture

The main purpose of this research is to highlight the relevance of the Green Plan in Japanese society, with special emphasis on its application in the city of Tokyo. This plan is positioned as a priority that not only focuses on the aforementioned metropolis, but is also available to its inhabitants, generating a positive impact. It is important to highlight that the fundamental purpose of this research is to understand the relevance of the so-called Green Plan in the creation and implementation of new green areas, as well as the associated strategies for the preservation of nature in the context …

Autonomous Underwater Vehicle Planning Using Hybrid D* Lite With Ppo And Td3: Experimental Design And Performance Analysis, Matthew J. Rice

Undergraduate Theses

Autonomous Underwater Vehicles (AUVs) face significant challenges in underwater navigation, including generating smooth paths, avoiding obstacles, and adapting to complex conditions. This paper introduces a hybrid path-planning algorithm, D-RL*, that integrates the D* Lite algorithm for efficient initial pathfinding with Deep Reinforcement Learning methods to refine paths for smoother trajectories. The proposed approach addresses D* Lite's inability to produce continuous, smooth paths and baseline Reinforcement Learnings’ failures in environments requiring significant detours. Experimental results in four progressively complex environments highlight D-RL*’s ability to plan smoother paths than D* Lite while training in a shorter amount of time and generating shorter …

Cultivating Community: A Mixed-Methods Study Examining Community Literacy Practices In The Secondary Ela Classroom, Anna Heilers

Undergraduate Theses

Past research on the relationship between community literacy and schooling has emphasized how educators can use community-based prior knowledge to teach students the privileged literacies associated with academia. Some researchers have discussed the potential for university-community partnerships that are mutually beneficial, but few have explored possibilities for change in the high school setting. Utilizing 24 survey responses and 2 interviews, this study sought to answer the following questions: Do high school class experiences have any impact on students’ community literacies? If they do, do they support or hinder their growth? I analyzed data using a combination of correlational analysis, axial …

Saving Private Unfaithful: An Argument For Administrative Separation And Action In Lieu Of Criminalizing Extramarital Sexual Conduct, Annelise Burgess

Washington and Lee Law Review Online

In order to keep America’s armed forces deadly, ESC must be decriminalized. The MCM’s 2019 update to start including non-heterosexual marriages and affairs tragically expands the reach of ESC. This Note presents new data on charging patterns of ESC in the Marines, highlighting the crime’s active use. ESC continues to overcompensate for behavior prejudicial to good order and discipline or service discrediting; this overcompensation results in subjecting non-prejudicial and non-service-discrediting behavior to criminal action, simultaneously infringing on service members’ constitutional rights and serving as fodder for public outcry. Military leaders should decriminalize ESC and alternatively penalize the behavior by administrative …

Brain-Targeted Reactive Oxygen Species In Hypertension: Unveiling Subcellular Dynamics, Immune Cross-Talk, And Novel Therapeutic Pathways, Renjun Wang, Min Wang, Dongshu Du, Zhiying Shan, Lanrong Bi, Qing-Hui Chen

Michigan Tech Publications

Hypertension (HTN) is a complex disease with significant global health implications, driven by neural and oxidative mechanisms. Reactive oxygen species (ROS), once considered mere metabolic byproducts, are now recognized as one of the key contributors to dysfunction of the autonomic nerve system, which involves the onset and progression of HTN. This review highlights the dynamic roles of ROS in neuronal signaling, subcellular compartmentalization, and brain-immune interactions, focusing on their impacts on synaptic remodeling, neuroinflammation, and epigenetic modifications within key autonomic regions such as the paraventricular nucleus and rostral ventrolateral medulla. We discuss novel ROS sources, including microglia-derived and endoplasmic reticulum …

A Case Of Milkweed Poisoning In Cattle In Colorado, Raye Walck, Brett Webb, Steve Ensley, Daniel Cook

Poisonous Plant Research (PPR)

Milkweeds, Asclepias spp., are herbaceous perennials of the Apocyanaceae family. Milkweeds contain several cardiac glycosides, cardenolides, that are toxic. Clinical signs associated with milkweed toxicity are generalized weakness, difficulty in breathing, rapid weak pulse, bloating, violent spasms, paralysis, and death. Here we report a clinical case of milkweed toxicity in cattle due to contaminated hay. Clinical signs observed in the poisoned animals were consistent with cardenolide toxicity. Milkweed was detected in the rumen contents of the poisoned cow using DNA metabarcoding. In summary, multiple lines of corroborative evidence were used to make the diagnoses of milkweed poisoning in this case.

Stable Heteroclinic Channels As A Decision-Making Model: Overcoming Low Signal-To-Noise Ratio With Mutual Inhibition, Natasha A. Rouse

Faculty Scholarship

Bio-inspired robot controllers are becoming more complex as we strive to make them more robust to, and flexible in, noisy, real-world environments. A stable heteroclinic network (SHN) is a dynamical system that produces cyclical state transitions using noisy input. SHN-based robot controllers enable sensory input to be integrated at the phase-space level of the controller, thus simplifying sensor-integrated, robot control methods. In this work, we investigate the mechanism that drives branching state trajectories in SHNs. We liken the branching state trajectories to decision-splits imposed into the system, which opens the door for more sophisticated controls-all driven by sensory input. This …

Application Of Quantum Entanglement To Explain The Healing Mechanism By Highly Diluted Homoeopathic Medicines, Bijay Krishna Chaudhuri, Biswadeep Chaudhuri

Indian Journal of Research in Homoeopathy

Background: The healing mechanism of highly diluted homoeopathic medicines (DHM) is not yet very clear.

Objectives: Our objective is to apply the concepts of entropy, information, and quantum mechanical principle of entanglement to find a model for explaining the healing mechanism of DHM.

Methodology: All living or non-living things are composed of dynamic microscopic quantum particles (electrons, protons, ions, etc.) which follow the basic properties of quantum mechanics such as quantum entanglement, superposition of quantum states and coherent interaction among these particles. The continuous change of thermodynamic entropies of the dynamic living cells leads to information change for cellular communication …

Effect Of Individualised Homoeopathic Intervention In Dyslipidaemia: An Open-Label, Randomised, Controlled, Exploratory Trial, Roja Varanasi, Rupali Bhalerao, Raveendar Ch, Raju Kolli, Ravi Sardala, R.V.R. Prasad, Paul Sumithran, M. Prakash Rao, Ramesh Dubashi, Kiranmayee R.G.R, S. Rajeeva, V. Sarathy, P.A. Rajakumari, Priyanka Srivastava, Anupriya Chaudhary, Gnnana Prakasham, P. Prasad, Arvind Kumar, Viqar A. Siddiqui, Praveen Oberai, Raj K. Manchanda

Indian Journal of Research in Homoeopathy

Background: Dyslipidaemia, the derangement of one or many of the lipoproteins is a major cause of cardiovascular events, causing 2.6 million deaths per year globally.

Objectives: This study evaluated the efficacy of individualised homoeopathic medicines with lifestyle modification in the management of dyslipidaemia.

Materials and Methods: This multicentric, open-label, randomised controlled exploratory trial was conducted at seven study sites under the Central Council for Research in Homoeopathy. Participants fulfilling the eligibility criteria were enrolled. The primary outcome was to evaluate changes in Low-Density Lipoprotein cholesterol at months 3 and 6. Secondary outcomes were to evaluate changes in total cholesterol, triglyceride, …

Air Traffic Trends And Uav Safety: Leveraging Automatic Dependent Surveillance–Broadcast Data For Predictive Risk Mitigation, Prasad Pothana, Paul Snyder, Sreejith Vidhyadharan, Michael Ullrich, Jack Thornby

Petroleum Engineering Student Publications

With the significant potential of Unmanned Aircraft Vehicles (UAVs) extending throughout various fields and industries, their proliferation raises concerns regarding potential risks within the national airspace system (NAS). To enhance the safe and efficient integration of UAVs into airport environments, this paper presents an analysis of temporal statistical patterns in flight traffic, the predictive modeling of future traffic trends using machine learning, and the identification of optimal time windows for UAV operations within airports. The framework was developed using historical Automatic Dependent Surveillance–Broadcast (ADS-B) data obtained from the OpenSky Network. Historical flight data from Class B, C, and D airports …

Dnajb6: A Potent Dnajb Chaperone In Regulating Tau Proteostasis, Abigail R. Esquivel

USF Tampa Graduate Theses and Dissertations

Neurodegenerative diseases often feature the pathological buildup of misfolded proteins, and tau is a principal culprit in multiple tauopathies. One chaperone of emerging interest is DnaJB6b, a member of the Hsp40/DnaJ family, which exhibits potent anti-aggregation activity against several disease-related proteins. Recent investigations highlight its unique capacity to recognize and neutralize aggregation-prone forms of tau. DnaJB6b appears potent against multiple variants of tau and may be acting against tau, in part, by directing misfolded tau toward proteasomal clearance. The first lines of evidence come from systematic chaperone screens, where DnaJB6b repeatedly emerged as a strong suppressor of tau seeding. Further …

Desistance, Emancipation, Empathy, And Pedagogy: The Incarcerated Teaching Artist’S Approach To Poetry, Ghostwrite Mike

Journal of Prison Education Research

The Art of Recovery and Therapy (ART) leisure time activity group at Valley State Prison (VSP) in Chowchilla, California, is a resident-led arts and humanities-based self-help forum that has been available to carceral state residents for more than a decade and is administered in collaboration with full-time, non-custody, civil servant facility staff (CDCR site, n.d.). ART is among the California Department of Corrections and Rehabilitation’s (CDCR) longest running and most autonomous creator habitats founded and facilitated entirely by resident practitioners. ART wields a codified state regulatory authority to function and fundraise (Cal. Code Regs. § 3233-3237, 3240) as well as …

Immersive Mixed-Reality Anatomy Lab, Cassidy Norkett

Honors Theses

The Mixed Reality Heart Anatomy Lesson was created to address the WMU Homer Stryker M.D. School of Medicine’s need for an interactive and dynamic laboratory lesson. The application allows for a more efficient way for medical students to learn and comprehend the material. The design and development of a mixed reality application running on smart glasses provides students with a situation aware, fully engaged, and immersive learning experience. The Apple Vision Pro device allows medical students to complete their labs by merging physiology and anatomy concepts through 3D models, object detection, self-assessments, and an artificial intelligence chatbot. There can be …

Research Highlights, Shruti Jain Vij, Charu Sehgal

Indian Journal of Research in Homoeopathy

Research Highlights

2025-03-28 Agenda Book, Morehead State University. Board Of Regents.

Morehead State Board of Regents Agenda Books and Meeting Minutes

Agenda booklet for the Board of Regents meeting of March 28, 2025, which includes the meeting minutes of the meeting held on February 7, 2025.

Deep Learning Function Implications For Handwritten Character Recognition Using Improved Mean Square Error Function, Bahera H. Nayef, Siti Norul Huda Sheikh Abdullah, Manal Mohammed

Baghdad Science Journal

Loss functions are used for estimating the accuracy of the classification models in Machine Learning. The error loss value measures whether the predicted labels match the true labels or are close to them. Handwritten character recognition is a pattern recognition problem. The progression of pattern recognition applications for offline image classification is rapidly improved by using deep learning techniques. Convolution Neural Networks (CNN) and the activation function are the most commonly used in deep learning. In addition, different loss functions are used to evaluate the performance of the model such as Categorical Cross-Entropy (CCE) and Mean Square Error (MSE). In …

Investigating The Proviral And Immunogenic Effects Of Sars-Cov-2 Accessory Protein 7a, Grant Michael Hawkins

Dissertations

SARS-CoV-2 and related sarbecoviruses encode a set of accessory proteins (3a, 3b, 6, 7a, 7b, 8, 9b, and 10) that control host responses to infection and promote virus growth. Of these accessory proteins, 7a is set apart by its intracellular localization near coronavirus (CoV) budding sites and its incorporation into secreted virions. Initial studies utilizing a virus-like particle (VLP) system identified significant proviral effects mediated by 7a, but the system lacked the context of an actual CoV infection. To investigate 7a functions during CoV infections, we constructed recombinant Mouse Hepatitis Viruses (rMHV strain A59) that express 7a genes. Comparative infections …

Refinement Of Megakaryocyte Lineage Commitment In Hematopoietic Stem And Progenitor Cells During Postnatal And Adult Hematopoiesis, Ryan Michael Mack

Dissertations

Mammalian hematopoiesis ensures the continuous production of specialized blood cells, yet the mechanisms that govern megakaryocyte/erythroid (MK/E) bifurcation remain incompletely understood. While HSPCs sustain all blood lineages, how transient waves of progenitors arise and adapt from fetal to adult stages is less clear. This gap in knowledge limits our capacity to precisely manipulate platelet and red blood cell outputs in both developmental and therapeutic contexts. Using refined gating strategies and various bulk- and single-cell transcriptomics, we dissected the traditional “common myeloid progenitor” and Multipotent Progenitor (MPP) compartment into multiple functionally distinct subsets (C1, C2, C3). Within C1, an ESAM⁺ fraction …

Systemic Antitumor Immune Response Of Doped Yttria Nanoscintillators Under Low-Dose X-Ray Irradiation, Onur Sahin, Yuri Mackeyev, Geraldine V Vijay, Soumyabrata Roy, Ashokkumar Meiyazhagan, Yasmin Zahra, Okan Tezcan, Valeria Gonzalez, Belal Abousaida, Holden R Wagner, Pearl Fernandes, Riaz Mowzoon-Mogharrabi, Bhanu P Venkatesulu, Cheng-En Hsieh, Joseph B K Kim, Subhiksha Raghuram, Xiang Zhang, Kristen A Miller, Guanhui Gao, Pankaj K Singh, Sang Hyun Cho, Rao V L Papineni, Pulickel M Ajayan, Sunil Krishnan

Faculty, Staff and Student Publications

Inadequate light penetration in tissues restricts photodynamic therapy to treating only superficial tumors. To enable x-ray-excited photodynamic therapy (XPDT) that targets deep-seated tumors, we synthesized a nanoscintillator-photosensitizer complex containing 5% Eu-doped Y2O3 fluorescing at 611 nanometers and decorated with SiO2 containing the scintillation-coupled photosensitizer methylene blue and a polyethylene glycol coating [PEGylated Y2O3:Eu@SiO2-methylene blue (pYSM)]. When irradiated, pYSMs generate singlet oxygen species in vitro, causing cytotoxicity with hallmarks of immunogenic cell death (calreticulin translocation to the cell membrane). Intravenously administered pYSMs home passively to pancreatic tumor xenografts and, upon 10 gray irradiation, cause significant tumor regression (P < 0.01). On combining XPDT with anti-PD1 immunotherapy, a distant nonirradiated tumor also regresses via an increase in intratumoral activated CD8+ cytotoxic T cells. Collectively, we advance a systemically delivered XPDT strategy that mediates an antitumor effect in both irradiated and nonirradiated (abscopal) tumors when coupled with immunotherapy, converting an immunologically "cold" tumor to an immunologically "hot" tumor.

Effects Of Prebiotic Phytocompound Administration In Gestational Diabetic Dams And Its Influence On Offspring Cognitive Outcomes, Gayathri Jagadeesan, Tushar K Das, Jennifer M Mendoza, Ghalya Alrousan, Maria P Blasco-Conesa, Parimelazhagan Thangaraj, Bhanu Priya Ganesh

Faculty, Staff and Student Publications

Gestational diabetes mellitus (GD)-induced gut dysbiosis in pregnant mothers may increase the risk of cognitive impairment and neurological disorders in both the mother and offspring as they age. Restoring gut balance could improve cognitive outcomes for both. Despite advancements in GD treatment, side effects have increased, and long-term neurocognitive impacts on offspring born to GD mothers remain underexplored. This study uses a GD mouse model, inducing pancreatic dysfunction in 3-month-old pregnant C57BL/6J mice with Streptozotocin. The efficacy and mechanism of the prebiotic phytocompound green leaf extract (

Assessing Cancer Therapeutic Efficacy In Vivo Using [2h7]Glucose Deuterium Metabolic Imaging, Mario C Chang, Vinay R Malut, Rohit Mahar, Anna Rushin, Marc A Mcleod, Geraldine L Pierre, Indu R Malut, Stephen J Staklinski, Max E Glanz, Mukundan Ragavan, Gaurav Sharma, Manoj Madheswaran, Arshee Badar, Aparna D Rao, Brian K Law, Michael S Kilberg, James H P Collins, Vikram D Kodibagkar, James A Bankson, Ralph J Deberardinis, Matthew E Merritt

Faculty, Staff and Student Publications

Metabolic imaging produces powerful visual assessments of organ function in vivo. Current techniques can be improved by safely increasing metabolic contrast. The gold standard, 2-[18F]fluorodeoxyglucose-positron emission tomography (FDG-PET) imaging, is limited by radioactive exposure and sparse assessment of metabolism beyond glucose uptake and retention. Deuterium magnetic resonance imaging (DMRI) with [6,6-2H2]glucose is nonradioactive, achieves tumor metabolic contrast, but can be improved by enriched contrast from deuterated water (HDO) based imaging. Here, we developed a DMRI protocol employing [2H7]glucose. Imaging 2H-signal and measuring HDO production in tumor-bearing mice detected differential glucose utilization across baseline tumors, tumors treated with vehicle control or …

Sitc Strategic Vision: Prevention, Premalignant Immunity, Host And Environmental Factors, Sasha E Stanton, Kristin G Anderson, Tullia C Bruno, Christian M Capitini, Mary L Disis, Jennifer Mcquade, Laszlo Radvanyi, Claire Vanpouille-Box, Jennifer Wargo, Kelly J Baines, Megan M Y Hong, Adnan Rajeh, Raymond H Kim, Phillip Awadalla, Lauren K Hughes, Saman Maleki Vareki

Faculty, Staff and Student Publications

Cancer immunotherapy has improved the survival of a subset of patients by harnessing the power of the immune system to find and destroy malignant cells. The immune system also protects the host by destroying developing premalignant and malignant tumors. Advancing our knowledge of premalignant immunity and immune changes seen in lesions that develop into invasive cancer versus those that regress offers an exciting opportunity to leverage the immune system for immune prevention and immune interception of premalignancy. Understanding the immune environment of premalignant lesions and how chronic inflammation plays a central role in the evolution of premalignancy is essential for …

"The Letting Of Blood": Evolutionary Perspectives On Violence In Cormac Mccarthy’S Western Worlds, Nicholas Adam Pankewycz

Electronic Theses and Dissertations Archive

Abstract: Pankewycz, Nicholas Adam. PhD. The University of Memphis. December 2024. “the letting of blood”: Evolutionary Perspectives on Violence in Cormac McCarthy’s Western Worlds. Theron Britt PhD. Through a close analysis of Cormac McCarthy's Western oeuvre, the dissertation examines how his depiction of violence reflects fundamental aspects of human nature, suggesting that the aggressive behaviors portrayed are inherent and shaped by environmental and evolutionary pressures. McCarthy's unflinching narratives provide insight into the darker facets of humanity, depicting scenes of brutality that challenge readers to confront the pervasive nature of violence in both American history and the human species. By situating …

Deep Learning (Cnn) For Detecting Road Infrastructure In Old Mosul City Using High-Resolution Aerial Imagery, Mustafa Ismat Abdulrahman, Muntadher Aidi Shareef, Alyaa Abbas Al-Attar

Baghdad Science Journal

Road networks and transportation infrastructure play a crucial role in many applications such as urban planning and environmental assessment. Remote sensing provides multispectral data that can be used to identify, extract, and map roads. However, accurate mapping of road networks from aerial imagery poses challenges due to the complexity of real-world road patterns. The aim of this study was to develop deep learning techniques for automated road extraction from aerial photographs. The study evaluated several convolutional neural network (CNN) architectures were including a hybrid spectral-spatial network (HybridSN). Models were assessed on a dataset of urban aerial images with lidar-derived ground …

Medicinal Plant Leaf Classification Using Deep Learning And Vision Transformers, Shahriar Hossain, Rizbanul Hasan, Jia Uddin

Baghdad Science Journal

Identification of medicinal plant leaves is very crucial as their cultivation and production are essential for the medicine industry. Many different classes of medicinal leaves look identical but serve different purposes in the medicine industry and have different remedies for different diseases. Hence it is imperative to use methods that are automated, faster, and produce good accuracy. Cutting-edge models have been trained to discern the subtle distinctions between various species of leaves, accounting for a myriad of factors such as leaf texture, shape, and color variations, which are often imperceptible to the human eye. In this research, Transfer learning (TL) …

2025-03-28, Board Of Regents, Murray State University

Board of Regents Meeting Minutes

No abstract provided.

An In Vivo Screen Identifies Nat10 As A Master Regulator Of Brain Metastasis, Jocelyn F Chen, Peng Xu, Wesley L Cai, Huacui Chen, Emily Wingrove, Xiaojian Shi, Wenxue Li, Giulia Biancon, Meiling Zhang, Amer Balabaki, Ethan D Krop, Elianna Asare, Yangyi Zhang, Mingzhu Yin, Toma Tebaldi, Jordan L Meier, Thomas F Westbrook, Stephanie Halene, Yansheng Liu, Hongying Shen, Don X Nguyen, Qin Yan

Faculty, Staff and Students Publications

Emerging evidence has shown that epigenetic regulation plays a fundamental role in cancer metastasis, the major cause of cancer-related deaths. Here, we conducted an in vivo screen for vulnerabilities of brain metastasis and identified N-acetyltransferase 10 (NAT10) as a driver of brain metastasis. Knockdown of NAT10 restrains cancer cell proliferation and migration in vitro and tumor growth and brain metastasis in vivo. The poorly characterized RNA helicase domain of NAT10 is critical for cell growth in vitro, while both RNA helicase and NAT domains are essential for primary tumor growth and brain metastasis in vivo. Mechanically, NAT10 promotes the …