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2025

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Tax Trends, Harry Z. Garian Dec 2025

Tax Trends, Harry Z. Garian

Tax Adviser

No abstract provided.


Prophet, Stephen D. Kelly Dec 2025

Prophet, Stephen D. Kelly

Valparaiso Fiction Review

No abstract provided.


The Secret, Kristen Hamelin Tracey Dec 2025

The Secret, Kristen Hamelin Tracey

Valparaiso Fiction Review

No abstract provided.


Angelfish Is Spinning, Anne Elliott Dec 2025

Angelfish Is Spinning, Anne Elliott

Valparaiso Fiction Review

No abstract provided.


Generating Interactive, Llm-Driven Annotations For Inclusion In Digital Image Files, Ilia Labzovsky, Danny Karmon Dec 2025

Generating Interactive, Llm-Driven Annotations For Inclusion In Digital Image Files, Ilia Labzovsky, Danny Karmon

Defensive Publications Series

While photographs capture visual information, they lack depth and interactivity. Contextual information, memories, stories, and related data associated with a photograph are external to the image file itself, and are scattered across applications, cloud services, or within the user’s mind. This disclosure describes techniques to enhance a digital image by automatically generating interactive annotations using a large language model (LLM) and incorporating the annotations into the image. Entities within a photo are identified and an LLM is instructed to generate an annotation object for the recognized entities. The annotation object is a self-contained package of data and instructions that specifies …


Integrating Generative Animations Of Photographs Into A Coherent Video Journey, Ilia Labzovsky, Danny Karmon Dec 2025

Integrating Generative Animations Of Photographs Into A Coherent Video Journey, Ilia Labzovsky, Danny Karmon

Defensive Publications Series

Users enjoy creating slideshows, animated videos, etc. that capture their trips. Current techniques to prepare such creations are limited by the content of the captured photographs and user knowledge of such features. This disclosure describes the use of artificial intelligence to automatically generate a dynamic video journey from a collection of user photographs. With user permission, an artificial intelligence model performs semantic analysis of user photos to infer the user’s geographic path during the photo capture journey. A generative video model accesses street-level images along the path and synthesizes a base video that simulates first-person movement along the path. The …


Ink And Ignorance: How Limitations In Research, Captivity And Recognition Obscure Cephalopod Science, Jacob Weniger Dec 2025

Ink And Ignorance: How Limitations In Research, Captivity And Recognition Obscure Cephalopod Science, Jacob Weniger

Saint John’s Preparatory School Student Work

This paper analyzes what the limitations are in modern ocean research and how they relate to the study of cephalopods. To understand this, the paper reviews many known cephalopod species to understand what is unknown about their biology. Research was then conducted to assess why certain aspects of species are unknown. Then each gap the specifications of the limitation and the solutions or strategies to overcome them was examined. This led to examinations of research tools, analysis bias, and public views. Understanding these issues is of great importance because it gives a comprehensive lay out of what needs to be …


Heroes By The Score, Owen J. Eastman Dec 2025

Heroes By The Score, Owen J. Eastman

Honors Projects

Historians have increasingly examined how media other than yellow journalism helped manufacture consent for American imperialism during the Spanish-American War, yet commercial sheet music—despite its ubiquity at the time—remains overlooked. This study addresses that gap by analyzing fifty pieces of sheet music published around the period, employing a mixed-methods approach that combines quantitative, qualitative, and comparative media analysis. The corpus reveals four dominant themes: memorializing the sinking of the Maine; Cuban “liberation” rhetoric that often referenced American ownership or influence over the island; military hero worship that personalized and justified expansion; and messages of national unity that permitted overseas territorial …


A Leap Of Good Faith: Intent Requirements In Trademark Applications Across Major Markets, Maximillian Scott Matiauda Dec 2025

A Leap Of Good Faith: Intent Requirements In Trademark Applications Across Major Markets, Maximillian Scott Matiauda

University of Miami International and Comparative Law Review

This Article examines how four major trademark regimes—the United Kingdom, United States, China, and European Union—define and regulate bad-faith trademark applications. It traces the historical and legislative foundations of intent-to-use doctrines, compares contemporary statutory frameworks and judicial interpretations, and evaluates pivotal developments such as the U.K. Supreme Court’s SkyKick ruling and China’s ongoing trademark reforms. Although the jurisdictions employ distinct legal tools, the Article finds a converging emphasis on curbing opportunistic or abusive filings. The Article ultimately advocates for greater international alignment in articulating and enforcing good-faith standards within trademark law.


Government Regulations-Consumer And Worker Protection Laws Business Law, Lorelei Salas Dec 2025

Government Regulations-Consumer And Worker Protection Laws Business Law, Lorelei Salas

Open Educational Resources

This assignment challenges the students to dive deeper into consumer and worker protection laws, by expanding their knowledge base or exploring personal experience with these issues.


Researchers Break Cancer's 'Shield' In New Metastasis Study, Clara Turnage Dec 2025

Researchers Break Cancer's 'Shield' In New Metastasis Study, Clara Turnage

University of Mississippi News

OXFORD, Miss. – Aggressive cancers can use blood vessels like roadways, speeding through the body and finding new places to grow. But new research shows that a drug in clinical trials may help stop the spread of cancer before it reaches its destination.


Engineered Multifunctional Drug-Loaded Dendrimer Nanoparticles For Glaucoma: Triple Mechanism Via Antioxidant Activity, Iron Chelation, And Enhanced Ocular Transport, Burhan Ates, Ashish Trital, Vimalin Jeyalatha Mani, Lei Xu, Jonathan Kenlee, Nuran Ercal, Hu Yang Dec 2025

Engineered Multifunctional Drug-Loaded Dendrimer Nanoparticles For Glaucoma: Triple Mechanism Via Antioxidant Activity, Iron Chelation, And Enhanced Ocular Transport, Burhan Ates, Ashish Trital, Vimalin Jeyalatha Mani, Lei Xu, Jonathan Kenlee, Nuran Ercal, Hu Yang

Chemistry Faculty Research & Creative Works

In this study, we developed multifunctional nanoparticles based on polyamidoamine (PAMAM) dendrimers functionalized with caffeic acid (CA) and poly (ethylene glycol) maleimide (PEGM) for the topical delivery of hydrophobic antiglaucoma drugs brimonidine (BM) and betaxolol (BX). The PAMAM-CA and PAMAM-CA-PEGM conjugates exhibited antioxidant and iron-chelating activities in a dose-dependent manner. BM- and BX-loaded dendrimer nanoparticles produced using a multi-inlet vortex mixer showed uniform spherical morphology (∼80 nm by TEM) and hydrated sizes of ∼135-144 nm by DLS. Both nano formulations demonstrated high cytocompatibility with human corneal epithelial cells and were nonirritant in the HET-CAM assay, with PEGM further improving cytocompatibility. …


Mechanistic Modelling And Parameter Estimation Of Heterogeneous Catalytic Synthesis Of Green Fuel, Rasheed U. Owolabi, Obinna P. Anele, Mohammed A. Usman Dec 2025

Mechanistic Modelling And Parameter Estimation Of Heterogeneous Catalytic Synthesis Of Green Fuel, Rasheed U. Owolabi, Obinna P. Anele, Mohammed A. Usman

Mansoura Engineering Journal

Investigation of the kinetics and mechanistic modelling of biodiesel synthesis through the reaction of castor oil with methanol under catalyzed conditions was carried out in this study. The reaction mechanisms of the Eley-Rideal, Langmuir-Hinshelwood-Hougen-Watson, and Hattori type were employed to identify the rate-determining or controlling step of the reaction. Thirteen rate expressions were developed for reactant adsorption, product desorption, and surface chemical reactions. The experimental data from Sanchez-Cantu et al. were used to validate the models, and the best-fitting model and parameter estimation were evaluated using SAS and MATLAB software. From the results, the Eley-Rideal mechanism with glycerol desorption as …


The Timing Of Pubertal Onset Affects Adults Anxiety Behavior In A Sex-Specific Manner, Evan Raubenolt Dec 2025

The Timing Of Pubertal Onset Affects Adults Anxiety Behavior In A Sex-Specific Manner, Evan Raubenolt

Honors Projects

This study aims to look at the relationship between the timing of pubertal onset and its long-term effects on adult anxiety behavior in rats. Though the topic of pubertal onset has been frequently discussed in developmental research, its exact effects have been inconsistent. Human models have shown that early and late maturing males are associated with a notable increase in adult anxiety behavior, while in rat models, similar sex-specific effects regarding anxiety have been demonstrated, though those studies focus on a causal relationship between exposure to stress and age of pubertal onset. This study first aims to examine that relationship …


Deep Learning For Underwater Manatee Counting And Tracking, Theodor Owchariw Dec 2025

Deep Learning For Underwater Manatee Counting And Tracking, Theodor Owchariw

Electronic Theses and Dissertations 2020 - Present

The Florida manatee (Trichechus manatus latirostris), a threatened marine mammal often found in coastal waters, require accurate monitoring to inform conservation strategies. However, traditional counting methods are hindered by observer bias and surface distortions. Recent advances in artificial intelligence (AI) address these challenges using captured aerial footage of manatees, demonstrating the potential of artificial intelligence for automating manatee counting. Still, various challenges arise hindering accurate counts.

Building on these studies, this work advances artificial intelligence with underwater footage, instance segmentation, data augmentation, and pseudo-labeling to automate manatee counting in data-scarce environments. Three experiments were conducted using 10%, 60%, and 90% …


Digital Confessions: A Genealogy Of Belonging, Obedience, And Platform Power, Mohammad M. Ibrahimi Dec 2025

Digital Confessions: A Genealogy Of Belonging, Obedience, And Platform Power, Mohammad M. Ibrahimi

Departmental Honors & Graduate Capstone Projects

This paper critiques social media as a moral architecture that shapes how individuals understand belonging, visibility, and selfhood. Drawing primarily on Nietzsche, with support from Foucault, Dostoevsky, and Zuboff, it explores why users continue to invest digital platforms with authority despite their widely recognized harms, treating social media less as a technological tool and more as a medium of belonging and livelihood. To provide a broader context for this critique, the paper situates social media within a genealogy of moral architectures, tracing developments from the Church, through capitalism as an ideology, and ultimately to contemporary digital platforms. In doing so, …


Water Circulation Beneath A Hovering Suas For Water Quality Monitoring Applications, Erin E. Hackett, Boone Fleenor, Jensine C. Coggin, Duvall Dickerson-Evans, Nikolaos Vitzilaios, Whitney E. Schuler, Paige K. Williams, Michael L. Myrick Dec 2025

Water Circulation Beneath A Hovering Suas For Water Quality Monitoring Applications, Erin E. Hackett, Boone Fleenor, Jensine C. Coggin, Duvall Dickerson-Evans, Nikolaos Vitzilaios, Whitney E. Schuler, Paige K. Williams, Michael L. Myrick

Marine Science

Water quality has traditionally been measured via in situ sensors and satellites. The latter has limited applicability for smaller inland water bodies, while the former requires significant logistics, labor, and expense for routine sampling, and reactive/spurious sampling is often not feasible as a result (e.g., sampling pre-/post-storm). Consequently, small uncrewed aircraft system-based (sUAS-based) sampling has emerged as a potential solution to bridge these sampling gaps and challenges. But sampling from an sUAS is complicated by the need to pump water from depth, rather than suspending a sensor from the sUAS, due to concern over sampling sUAS-impacted waters. Here, we measure …


Gastrectomy Promoted Diabetes Remission Involves The Molecular Clock And Epigenetic Mechanisms In A Rat Model Of Lean Type 2 Diabetes., Aurélie Le Lay, François Brial, Claude Rouch, Xiaojian Shao, Mathieu Bourgey, Kazuhiro Sonomura, Huiting Ou, Sara Ghezzal, Mylène Vincent, Marylène Rugard, Karine Audouze, Jiannis Ragoussis, Fumihiko Matsuda, Guillaume Bourque, Elin Grundberg, Mark Lathrop, Christophe Magnan, Dominique Gauguier Dec 2025

Gastrectomy Promoted Diabetes Remission Involves The Molecular Clock And Epigenetic Mechanisms In A Rat Model Of Lean Type 2 Diabetes., Aurélie Le Lay, François Brial, Claude Rouch, Xiaojian Shao, Mathieu Bourgey, Kazuhiro Sonomura, Huiting Ou, Sara Ghezzal, Mylène Vincent, Marylène Rugard, Karine Audouze, Jiannis Ragoussis, Fumihiko Matsuda, Guillaume Bourque, Elin Grundberg, Mark Lathrop, Christophe Magnan, Dominique Gauguier

Manuscripts, Articles, Book Chapters and Other Papers

Bariatric surgery results in type 2 diabetes (T2D) improvement. To identify mechanisms associated with gastrectomy-promoted T2D remission in lean individuals, we performed pathophysiological, behavioural and molecular (liver transcriptome, metabolome and lipidome) investigations in the Goto-Kakizaki (GK) model of spontaneously-occurring non-obese T2D following vertical sleeve gastrectomy (VSG) or sham operation. VSG resulted in sustained reduction in hyperglycemia and changes in nycthemeral feeding patterns and activity. Liver transcriptome and lipidome profiling pointed to changes in the expression of genes involved in inflammation, PPAR signalling and fatty acid metabolism, and in the regulation of phosphatidylcholine and lysophosphatidylethanolamine classes. Deeper analysis revealed altered expression …


Spike Timing Depended Plasticity Produces Unsupervised Learning Of Synergistic Muscle Feedback In A Synthetical Neural Network, Mark Allen Pupkiewicz Dec 2025

Spike Timing Depended Plasticity Produces Unsupervised Learning Of Synergistic Muscle Feedback In A Synthetical Neural Network, Mark Allen Pupkiewicz

Dissertations and Theses

This study investigates how type Ia feedback from muscle spindles can be organized into groups representing agonistic muscle pairs through Spike Timing Dependent Plasticity (STDP). A single degree of freedom joint is actuated with four biologically modeled muscles forming two agonistic pairs. In order to emulate the sensory dynamics of biological muscle spindles, sensors in the model record the active length and velocity states of each muscle, the two primary factors eliciting type Ia afferent responses. In biological networks, synapses from Ia sensory neurons frequently activate interneurons representing agonistic muscle sources. This research investigates whether this organization can emerge in …


Investigation Of The Endogenous Opioid Neural Circuitry In Pain, Erin Nicole Bobeck Dec 2025

Investigation Of The Endogenous Opioid Neural Circuitry In Pain, Erin Nicole Bobeck

Funded Research Records

No abstract provided.


Usu Subaward: Creation Of A Cooperative Bs Degree Program For The Marianas Islands And Beyond, Abby Benninghoff Dec 2025

Usu Subaward: Creation Of A Cooperative Bs Degree Program For The Marianas Islands And Beyond, Abby Benninghoff

Funded Research Records

No abstract provided.


Mapas, Marcos Y Meta-Comunicación: Bases Epistemológicas Para Una Teoría Del Juego Derrol De Mesa En Las Industrias Creativas / Maps, Frames, And Metacommunication: Epistemological Foundations For A Theory Of Tabletop Role-Playing Games In The Creative Industries, Cristo Leon Ph.D. Dec 2025

Mapas, Marcos Y Meta-Comunicación: Bases Epistemológicas Para Una Teoría Del Juego Derrol De Mesa En Las Industrias Creativas / Maps, Frames, And Metacommunication: Epistemological Foundations For A Theory Of Tabletop Role-Playing Games In The Creative Industries, Cristo Leon Ph.D.

STEM for Success Resources

Artículo académico de Cristo León (2025) sobre juegos de rol de mesa, teoría de marcos y meta-comunicación en las industrias creativas. El estudio propone una base epistemológica para comprender cómo los juegos de rol coordinan identidades, ficciones, acciones, agencia múltiple y niveles diegéticos mediante procesos colaborativos de creación narrativa. Publicado en Game Studies e as Indústrias Criativas, 5(2).


Ecological Drivers Of Habitat Selection And Maternal Survival In Female Mule Deer (Odocoileus Hemionus), Brady R. Knight Dec 2025

Ecological Drivers Of Habitat Selection And Maternal Survival In Female Mule Deer (Odocoileus Hemionus), Brady R. Knight

Theses and Dissertations

Understanding the ecological and biological factors that influence habitat selection by mule deer (Odocoileus hemionus) is crucial for effective management. Mule deer select cover, forage, and water, each critical to energy acquisition and survival of mule deer. Here, we evaluate the factors that influence habitat selection and reproductive decisions by mule deer . In chapter one we evaluate the influence of treatments to restore quaking aspen (Populus tremuloides) on habitat selection by mule deer. We hypothesized that mule deer would not use habitats randomly because of variability in nutrition and perceived risk of predation. We predicted that areas with aspen …


Primary And Secondary Hyperaldosteronism, Joanna Lam Dec 2025

Primary And Secondary Hyperaldosteronism, Joanna Lam

Senior Honors Theses

Hyperaldosteronism is characterized by the excess production of aldosterone in the body. This disorder manifests in two subtypes: while primary hyperaldosteronism is due to the excess secretion of aldosterone from the adrenal glands, secondary hyperaldosteronism originates from imbalances elsewhere in the body. Here, recent literature will be reviewed to examine the etiology and effects of both subtypes of hyperaldosteronism across molecular, cellular, and organ levels. Current diagnostic and treatment options for both subtypes of this disorder will also be reviewed, as well as recent research examining the prevalence of hyperaldosteronism over varying demographics.


Elephant In The Classroom: How Ethical Ai Can Improve Student Success, Ibrahim Kocaman, Daniel A. Cutrer Dec 2025

Elephant In The Classroom: How Ethical Ai Can Improve Student Success, Ibrahim Kocaman, Daniel A. Cutrer

Publications

The integration of artificial intelligence (AI) into teaching and learning in higher education without compromising academic integrity is a pressing issue. To make the benefits of generative AI (GenAI) available to students while upholding principles of ethics and academic honesty, the authors implemented an ethical use of AI policy in their Introduction to Research Methods at Embry-Riddle University. The authors hypothesized and found that allowing ethical utilization of AI would lead to higher student engagement and academic success. These findings offer valuable insights for higher education programs and educators, particularly in security studies.


Mitochondrial Insoluble Aggregates In Aging And Alzheimer’S Disease Models: Cross-Species Proteomic Integration, Identification Of Conserved Candidates, And Pharmacological Disruption Of Eef-2 Interactions, Sonu Pahal Dec 2025

Mitochondrial Insoluble Aggregates In Aging And Alzheimer’S Disease Models: Cross-Species Proteomic Integration, Identification Of Conserved Candidates, And Pharmacological Disruption Of Eef-2 Interactions, Sonu Pahal

Theses and Dissertations

Protein aggregation within mitochondria emerges early in both aging and Alzheimer’s disease (AD) and contributes to progressive loss of proteostasis. Insoluble mitochondrial aggregate fractions from Caenorhabditis elegans revealed extensive enrichment of metabolic and translational proteins that also appear in human Alzheimer hippocampal aggregates. Comparative analysis across age and genotype identified a conserved subset of aggregation-prone proteins, several of which cluster around elongation factor 2 (eEF-2), a regulator of ribosomal translocation and energy coupling. Cross-species integration defined a network in which eEF-2 links chaperones, metabolic enzymes, and RNA-binding proteins that co-aggregate in both human Alzheimer material and nematode models. Functional tests …


Intouch Week Of December 8, 2025, New York Medical College Dec 2025

Intouch Week Of December 8, 2025, New York Medical College

InTouch

No abstract provided.


Polycystin-2 Is Cardioprotective Against Myocardial Infarction By Regulating The Calcium-Mediated Er-Stress Response, Virdjinija Vuchkovska Dec 2025

Polycystin-2 Is Cardioprotective Against Myocardial Infarction By Regulating The Calcium-Mediated Er-Stress Response, Virdjinija Vuchkovska

Dissertations

Patients with autosomal polycystic kidney disease (ADPKD) have an increased risk and worse outcomes after acute myocardial infarction, but the mechanism for this is unknown. Polycystin 2 (PC2), one of the two main proteins mutated in ADPKD, is a calcium permeant channel that localizes to the ER/SR. In non-cardiac cells, PC2 regulates the unfolded protein response (UPR) pathway under ER stress. However, whether PC2 is cardioprotective against ER stress is unknown. We found that PC2 expression increased in cardiomyocytes from human ischemic hearts and infarcted murine hearts. Cardiomyocyte-specific PC2 KO (PC2 KO) mice had worsened cardiac function after myocardial infarction …


Using Light To Dissect Mechanisms Of Septin Recruitment, Shreya Chandrasekar Dec 2025

Using Light To Dissect Mechanisms Of Septin Recruitment, Shreya Chandrasekar

Dissertations

Cells interpret biochemical and mechanical signals through dynamic regulation of the cytoskeleton and adhesion complexes, enabling key processes such as shape adaptation, force generation and migration. As these signals vary in both time and space, they can be challenging to resolve using traditional bulk assays. To overcome this limitation, we employ light-based optogenetic tools to reversibly modulate biochemical signals and mechanical equilibrium within cells. Specifically, we use the iLID optogenetic approach to locally activate signaling and manipulate contractility within the cytoskeleton for the purpose of investigating the role of RhoA and contractility on septin organization and adhesion protein localization. We …


Imaging Reactive Oxygen Species With L-012 Reveals Neutrophil Extracellular Trap Formation In Pancreatic Ductal Adenocarcinoma, Angisha Basnet, Kaitlyn M Landreth, Michael Sestito, Kristen Ranson, Seth T Gammon, David Piwnica-Worms, Brian A Boone, Tracy W Liu Dec 2025

Imaging Reactive Oxygen Species With L-012 Reveals Neutrophil Extracellular Trap Formation In Pancreatic Ductal Adenocarcinoma, Angisha Basnet, Kaitlyn M Landreth, Michael Sestito, Kristen Ranson, Seth T Gammon, David Piwnica-Worms, Brian A Boone, Tracy W Liu

Faculty, Staff and Student Publications

Neutrophils, key effector cells of the innate immune system, combat pathogens through mechanisms including the production of reactive oxygen species (ROS) and the release of neutrophil extracellular traps (NETs). While these responses are critical for host defense, prolonged elevation of ROS and dysregulated NETosis mediated by neutrophils have been implicated in autoimmune diseases, chronic inflammation, and cancer. In pancreatic ductal adenocarcinoma (PDAC), a highly aggressive and inflammatory malignancy, an increase in neutrophils infiltrating the tumor microenvironment promotes cancer progression and metastasis through increased ROS production and NET release. Using bioluminescence imaging with the reporter L-012 and NET assays, we assessed …