Digital Commons Network^™

Book Review: British Grand Strategy In The Age Of American Hegemony, Frank L. Jones

Parameters Bookshelf – Online Book Reviews

Author: William D. James

Reviewed by Dr. Frank L. Jones, distinguished fellow, US Army War College

Dr. Frank L. Jones, a distinguished fellow of the US Army War College, provides a useful and comprehensive review of author William D. James’s first book, “an excellent study for members of the defense community who want to understand British grand strategy historically or aspire to policy-making or strategy-making positions and need a sound introduction.” Jones outlines James’s main arguments and the value of the case studies presented, including the “East of Suez” case study, a “vivid example of strategic adjustment where timing, domestic …

Tuning Of The Structural And Electrical Properties Of Thermo-Luminescent Tungsten-Doped Indium Oxide Thin Film, C. Aparna, Pramoda Kumara Shetty, M. G. Mahesha

Open Access archive

This paper aims to synthesize tungsten-doped indium oxide thin film and to study its properties. Films with different tungsten dopant concentrations were deposited using the technique of spray pyrolysis. Raman spectroscopy and X-ray diffraction were used to investigate the structural features. It confirms the polycrystalline cubic structure of W-doped indium oxide. The morphological change observed with doping supports the preferred plane orientation change. Optical properties were studied using UV-visible spectroscopy. The photoluminescence spectra showed both near-band emission (NBE) and violet-blue emission. The suitability of the material for gamma sensing applications was confirmed by thermoluminescence (TL) spectroscopy. The binding energy obtained …

Ge/Sige Quantum Wells: Material For The Post-Moore Era, Troy Alexander Hutchins-Delgado

Optical Science and Engineering ETDs

This dissertation demonstrates high-quality germanium quantum wells on a 200 mm silicon wafer platform, enabling novel device possibilities. Partnering with a commercial silicon-germanium epitaxy supplier, we obtained shallow, undoped germanium quantum wells with high-crystalline quality, confirmed through x-ray diffraction, secondary ion mass spectroscopy, high-resolution scanning transmission electron microscopy, and energy dispersive x-ray spectroscopy. Hall bar devices fabricated on single quantum wells revealed that surface preparation can tune transport properties while maintaining peak mobilities around 10⁵ cm²V⁻¹s⁻¹. Manganese-germanide spintronic contacts were integrated via solid-state reaction, with contact quality assessed through Schottky diodes, transfer length …

Hypoxia-Inducible Factor 3Α1'S Role In Promoting Iron Loading, Tumorigenesis, And Metastasis In Colorectal Cancer, Luke B. Villareal

Biomedical Sciences ETDs

The interplay between hypoxia and iron metabolism drives colorectal cancer (CRC) progression. This dissertation investigates hypoxia-inducible factor 3α1 (HIF-3α1), a protein linked to poor CRC outcomes, focusing on its roles in metastasis, epithelial-to-mesenchymal transition (EMT), and iron loading via transferrin receptor (TFRC). HIF-3α1 promotes CRC cell migration by upregulating zinc finger E-box binding homeobox 2 (ZEB2) and suppressing N-myc downstream-regulated gene 1 (NDRG1), while TFRC-mediated iron accumulation supports tumor growth and survival. Iron chelation reduced EMT markers, migration, and tumor growth, highlighting iron's critical role. Additionally, HIF-3α1-induced TFRC expression altered nucleotide synthesis enzymes carbamoyl-phosphate synthetase-aspartate transcarbamoylase-dihydroorotase (CAD) and phosphoribosyl pyrophosphate …

Synthesis Of Glycan Antigens For Therapeutic Antibodies And Glycoconjugate Vaccines, Synthesis Of An Inflammatory Pentasaccharide, And Design And Synthesis Of Ceragenins For Use In Medical Devices And Osteomyelitis, Shawn Gubler

Theses and Dissertations

A promising approach in combatting infections from antibiotic resistant bacteria/fungi is using therapeutic monoclonal antibodies (mAbs) that can bind the outer surfaces of microbes. We have developed a synthetic vaccine platform that can rapidly generate mAbs against surface glycans from desired strains, such as lipopolysaccharides and capsular polysaccharides. To create therapeutic antibodies against Ruminococcus gnavus, Burkholderia multivorans, and Staphylococcus aureus, we synthesize glycan antigens from each strain that are necessary for use in our glycoconjugate vaccine platform. Blooms of the Gram-positive bacterium Ruminococcus gnavus have been correlated with inflammatory bowel disease, and recently a polysaccharide produced by this organism was …

Re: Comment Letter For Final Bpsou Insufficiently Reclaimed Sites Belle Of Butte (Bres No. 8 & Ur-39) Remedial Action Work Plan (Rawp) Request For Change Ir-2024-Ra-01 (Dated December 3, 2024), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Port-Wine Stain Treatment With 577-Nm Laser: Treatment Outcomes Of Superficial Versus Deep Lesions, Yulia Siskawati

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Port-wine stains (PWS), or capillary malformations (CM), are congenital vascular anomalies characterized by gradual enlargement of the superficial cutaneous vascular plexus, leading to low-flow malformations in the skin. Laser therapy remains the preferred treatment for PWS. The 577-nm vascular laser system is particularly suited for treating cutaneous vascular disorders. This study evaluates the efficacy of the 577-nm vascular laser for both superficial and deep PWS lesions.

Case Illustration: Three adult patients, all aged over 17 years old, were treated with the 577-nm laser. In the first case with deeper PWS, four treatment sessions resulted in flattening of hypertrophic areas, …

Automate To Create: Simplifying Workflows In Small Film Productions, Adam Bonny

Undergraduate Honors Theses

This thesis aims to provide guidance for film students and small in- dependent productions on streamlining their film productions, with a particular focus on simplifying the postproduction workflow. While there’s a significant written component to this thesis, it remains classified as a ‘creative project’ and thus may not look like traditional scholarly research of media arts in some as- pects, mainly by focusing on the technical considerations of filmmaking rather than critical study and media theory. It is split into two parts. First, it will detail the research and the decision-making behind the creation of a Notion template aimed at …

Exploring The Accuracy Of Interferometric Quantum Measurements Under Conservation Laws, Nicolò Piccione, Maria Maffei, Andrew N. Jordan, Kater W. Murch, Alexia Auffèves

Mathematics, Physics, and Computer Science Faculty Articles and Research

A (target) quantum system is often measured through observations performed on a second (meter) system to which the target is coupled. In the presence of global conservation laws holding on the joint meter-target system, the Wigner-Araki-Yanase theorem and its generalizations predict a lower bound on the measurement’s error (Ozawa’s bound). While practically negligible for macroscopic meters, it becomes relevant for microscopic ones. Here, we propose a simple interferometric setup, arguably within reach of present technology, in which a flying particle (a microscopic quantum meter) is used to measure a qubit by interacting with it in one arm of the interferometer. …

The Cowl - V. 88 N. 10 - December 12, 2024

The Cowl

The Cowl - student newspaper of Providence College. Vol. 88 No. 10 - December 12, 2024. 20 pages.

Prevention Innovations Winter 2024 News, Prevention Innovations Research Center

PIRC Newsletter

No abstract provided.

Closed Domain Question Answering With Language Models: Application Of Retrieval-Augmented Generation And Parameter Efficient Fine-Tuning In Healthcare, Aaron Cummings

Master's Theses

Dementia care presents significant challenges for informal caregivers, particularly in managing behavioral symptoms that affect over 90% of individuals with Alzheimer’s Disease and Related Dementias (ADRD) during the moderate-to-severe stages. These symptoms, including agitation, wandering, and repetitive activities, impose emotional and physical burdens on caregivers, often exacerbated by a lack of reliable, accessible, and personalized resources. Non-pharmacological interventions, while evidence-based, are underutilized due to knowledge gaps and the inefficiency of traditional training and information retrieval methods.

This research explores the adaptation of large language models (LLMs) to address these challenges by developing a framework for closed-domain Question Answering (QA) systems, …

An Integrative Review Of Trauma Informed Care With Pediatrics To Minimize Psychological Sequelae Post Discharge, Amber Lee, Courtney Heinzelman

Master's Projects

Each year, a significant number of children sustain injuries requiring hospitalization, and while many recover physically, some face long-term psychological challenges such as post-traumatic stress, anxiety, and depression. This integrative review focuses on adolescents aged 13–18 who have experienced accidental trauma, exploring how trauma-informed care (TIC) in nursing compares to traditional approaches in reducing psychological impacts after discharge. Research suggests that many young patients report mental health symptoms for months following traumatic events. Trauma-informed care prioritizes principles such as safety, trust, peer support, and empowerment, aiming to reduce emotional distress and promote recovery. This review examines the application of these …

Gpu Exploration Using Pycuda, Prudhvi Sai Akulapally

Masters Projects

This project investigates the implementation and optimization of parallel computing techniques using GPU acceleration frameworks such PyCuda. With the increasing demand for high-performance solutions in data-intensive applications, GPUs offer a compelling alternative to traditional CPU-based processing. The primary objective of this work is to harness the computational power of GPUs to achieve significant performance enhancements for complex workloads. The study focuses on two essential research questions: How effectively can PyCuda accelerate computational tasks, and what measurable performance gains can be achieved compared to CPU-based implementations? By addressing these questions, this project explores the applicability of GPU programming in tasks such …

Analysis Of Natural Structures And Chemical Mapping Data Reveals Local Stability Compensation In Rna, Robert L. Cornwell-Arquitt, Riley Nigh, Michael T. Hathaway, Joseph D. Yesselman, David A. Hendrix

Department of Biochemistry: Faculty Publications

RNA molecules adopt complex structures that perform essential biological functions across all forms of life, making them promising candidates for therapeutic applications. However, our ability to design new RNA structures remains limited by an incomplete understanding of their folding principles. While global metrics such as the minimum free energy are widely used, they are at odds with naturally occurring structures and incompatible with established design rules. Here, we introduce local stability compensation (LSC), a principle that RNA folding is governed by the local balance between destabilizing loops and their stabilizing adjacent stems, challenging the focus on global energetic optimization. Analysis …

Evidence-Based Strategies To Improve Retention Among Nurses In A Health Care Setting, Lilian Adamu

Walden Dissertations and Doctoral Studies

Retaining nurses is an ongoing challenge in the field of health care settings, particularly in health care environments. Because of the scarcity of nurses, health care agencies have depended on temporary and part-time nurses under short-term agreements, leading to heightened levels of stress and burnout, higher rates of employee turnover, reduced nursing income, and greater costs for the agency. The project site recognized nursing burnout and its issues, and nurse retention efforts shifted their focus to reducing burnout and stress among nurses. The literature findings emphasized the adverse effects of nurse burnout and stress in health care agencies and advocated …

Social Worker Experiences Providing Mental Health Therapy To Iowa Lgbtq+ Youth, Kathy Jochims

Walden Dissertations and Doctoral Studies

High rates of untreated mental health issues and suicidality among LGBTQ+ youth, exacerbated by isolation and rejection in rural areas, demonstrate an urgent necessity for preventive and responsive mental health care. However, access to these essential services remains limited in many rural areas. This study involved using a generic qualitative design to explore the experiences of social workers providing mental health therapy to LGBTQ+ youth in rural Iowa, and presence of cultural humility in social worker practices. The cultural humility theory was chosen as the theoretical framework. Semistructured interviews with 10 Iowa social workers were evaluated using thematic analysis. Study …

Simple Steps To Help Beat The Blues This Holiday Season From A Unh Mental Health Expert, Robbin Ray

UNH Today Archive

No abstract provided.

Personalized And Culturally Tailored Features Of Mobile Apps For Gestational Diabetes Mellitus And Their Impact On Patient Self-Management: Scoping Review, Catherine Jones, Yi Cui, Ruth Jeminiwa, Elina Bajracharya, Katie Chang, Tony Ma

College of Pharmacy Faculty Papers

BACKGROUND: Gestational diabetes mellitus (GDM) is an increasingly common high-risk pregnancy condition requiring intensive daily self-management, placing the burden of care directly on the patient. Understanding personal and cultural differences among patients is critical for delivering optimal support for GDM self-management, particularly in high-risk populations. Although mobile apps for GDM self-management are being used, limited research has been done on the personalized and culturally tailored features of these apps and their impact on patient self-management.

OBJECTIVE: This scoping review aims to explore the extent to which published studies report the integration and effectiveness of personalized and culturally tailored features in …

Comparative Efficacy, Safety, And Oncological Outcomes Of Percutaneous Thermal And Chemical Ablation Modalities For Recurrent Metastatic Cervical Lymphadenopathy From Thyroid Cancer, Eman A. Toraih, Siva Paladugu, Rami M. Elshazli, Mohammad M. Hussein, Hassan Malik, Humza Pirzadah, Ahmed Abdelmaksoud, Salem I. Noureldine, Emad Kandil

School of Medicine Faculty Publications

Background: Thermal and chemical ablation techniques may consolidate recurrent metastatic cervical lymph nodes as alternatives to repeat neck dissection in thyroid cancer patients. This meta-analysis aims to compare the efficacy and safety across modalities. Methods: Four databases were searched for studies on radiofrequency (RFA), microwave (MWA), laser (LA), and ethanol ablation (EA) treating metastatic cervical nodes from thyroid cancer. The outcomes analyzed included treatment response, oncologic control, and complications. Random effects meta-analytical pooling was conducted. Results: There were 25 studies (n = 1061 nodes) examining the four ablation methods. Patients showed comparable baseline characteristics and initial lymph node sizes ranging …

The 2024 Nobel Prize In Physiology Or Medicine: Microrna Takes Center Stage, George A. Calin, Florent Hubé, Michael R. Ladomery, Nicholas Delihas, Manuela Ferracin, Laura Poliseno, Luca Agnelli, Suresh K. Alahari, Ai-Ming Yu, Xiao-Bo Zhong

School of Medicine Faculty Publications

The Non-coding Journal Editorial Board Members would like to congratulate Victor Ambros and Gary Ruvkun, who were jointly awarded the 2024 Nobel Prize in Physiology or Medicine for their groundbreaking discovery of microRNAs and the role of microRNAs in post-transcriptional gene regulation, uncovering a previously unknown layer of gene control in eukaryotes [...].

Stellar Properties From A Self-Consistent Analysis, Pius Privatus, Pulapa V Kanaka Rao, Cirino Pappalardo

Tanzania Journal of Science

Galaxies’ spectral energy distribution (SED) has been explored through the use of spectral synthesis codes. Most of the codes so far are solely stellar and assume a negligible nebular contribution. Fitting Analysis using Differential Evolution Optimisation (FADO) is the first spectral synthesis tool to consider the nebular contribution. The study examines how the primary stellar attributes are affected when FADO is applied to the Max Planck Institute for Astrophysics and Johns Hopkins University (MPA-JHU) data, namely the star-formation rate, metallicity, and stellar mass. The findings show that nebular emission results in the change of the slope of the equation of …

Predictive Modeling And Sustainability Assessment Of Hydrothermal Liquefaction Of Seaweeds: A Techno-Economic And Life Cycle Analysis Approach, Micheal O. Asama

Mechanical Engineering Theses

This study presents comprehensive predictive models and an economic and environmental assessment of HTL for converting macroalgae into biofuels and valuable co-products. Predictive models were developed based on experimental kinetic data to simulate batch HTL of brown seaweed, capturing the yields of biocrude, gas, biochar, and water-soluble compounds as functions of key process variables, including temperature, time, pressure, and water-to-biomass ratio. Analysis of Variance (ANOVA) confirmed that temperature and residence time significantly affect biocrude yield, with an optimal yield of 23% achieved at 283°C, 200 bar, 54 minutes, and a 10:1 water-to-biomass ratio. The model’s predictive accuracy was validated with …

Top Tier 2.0: Community Partnerships, University Of Nevada, Las Vegas

Focus on Top Tier 2.0

Community Partnerships have a positive long-term impact on our local communities. UNLV leverages resources for the public good to advance the university and the communities it serves. The value of the university is demonstrated through collaboration and engagement with the community to provide expertise, service, and support.

Book Review: Deterrence In The 21st Century: Statecraft In The Information Age, Timothy L. Thomas

Parameters Bookshelf – Online Book Reviews

Authors: Eric Ouellet, Madeleine D’Agata, and Keith Stewart

Reviewed by Lieutenant Colonel Timothy L. Thomas (US Army, retired), analyst and Parameters editorial board member

Analyst Timothy L. Thomas provides a useful overview of “well-documented and thought-provoking compilation of Canadian perspectives on the interaction of modern-day deterrence postures affected by disinformation threats.” Thomas notes that “the book offers many new concepts for senior defense community experts to consider regarding deterrence and disinformation concepts and an expansive bibliography.” He also highlights the book’s treatment of China, Russia, and Hamas and writes that “[t]he numerous deterrence types . . . indicate that classical …

Book Review: Judgment At Tokyo: World War Ii On Trial And The Making Of Modern Asia, Peter M. Erickson

Parameters Bookshelf – Online Book Reviews

Author: Gary J. Bass

Reviewed by Lieutenant Colonel Peter M. Erickson (US Army), PhD, Deputy G35, US Army Europe and Africa

Lieutenant Colonel Peter M. Erickson, PhD, provides a valuable overview of Gary J. Bass’s explanation of why the post–World War II Tokyo trials “were a relative failure.” He highlights how a lack of impartiality, the “legacy of empire,” and the judges’ backgrounds and motivations affected the trials. Erickson calls the book “a must-read for Defense community leaders who often wrestle with the strict legality of America’s tactical actions and the broader and deeper moral impacts of its strategic endeavors.”

Onycholysis In An Elderly Woman: Proposal For Treatment With Coix Seed Extract Administration, Yasuhiro Horiuchi

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: The exact etiology of onycholysis, which is characterized by the painless separation of the nail from the nail bed, remains unclear. Currently, there are no established effective treatments for this condition. Coix seed extract (C-S extract), a traditional Chinese medicine, is recognized for its various biological properties.

Case Illustration: This report describes a case of onycholysis affecting the left index finger of a 62-year-old female patient, with initial symptoms appearing three months prior. Despite ongoing internal administration of C-S extract, the patient experienced a recurrence of onycholysis on both the index finger and pinky finger of the left hand …

Lazarin, Burt, Caitlin Omey

Bronx Jewish History Project

Summarized by Avi Frank

Burt Lazarin was born in 1944 and grew up in the Bronx in the Highbridge and Williamsbridge neighborhoods. His family came from Eastern European Jewish backgrounds, with his father’s side immigrating from Lithuania and his mother’s from a region that later became part of Belarus. Lazarin describes growing up in a working to lower-middle-class household, first in a small apartment in Highbridge and later, in 1952, moving to a larger two-family home in Williamsbridge with his parents, brothers, and extended family. Although not religious, Lazarin recalls a strong sense of Jewish identity shaped by family traditions, …

Safety, Immunogenicity, And Efficacy Of A Recombinant Vesicular Stomatitis Virus Vectored Vaccine Against Severe Fever With Thrombocytopenia Syndrome Virus And Heartland Bandavirus, Philip Hicks, Tomaz B. Manzoni, Jonna B. Westover, Raegan J. Petch, Brianne Roper, Brian B. Gowen, Paul Bates

Animal, Dairy, and Veterinary Science Faculty Publications

Background: Severe fever with thrombocytopenia syndrome virus (STSV) is a recently emerged tickborne virus in east Asia with over 18,000 confirmed cases. With a high case fatality ratio, SFTSV has been designated a high priority pathogen by the WHO and the NIAID. Despite this, there are currently no approved therapies or vaccines to treat or prevent SFTS. Vesicular stomatitis virus (VSV) represents an FDA-approved vaccine platform that has been considered for numerous viruses due to its low sero-prevalence in humans, ease in genetic manipulation, and promiscuity in incorporating foreign glycoproteins into its virions. Methods: In this study, we developed a …

Systemic Antibiotic Selection In Skin And Soft Tissue Infections, Shafira Anindya Purnawan, Windy Keumala Budianti, Sandra Widaty

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Antibiotics are used in daily practice. To properly select antibiotics, it is important to pay attention to the definitive diagnosis, class of antibiotic, dose, interval, route of administration, and exact duration of use.

Discussion: The World Health Organization (WHO) categorizes antibiotics into three groups: Access, Watch, and Reserve—known as the AWaRe classification—to help guide appropriate usage and combat antibiotic resistance. The Gyssens flowchart serves as a valuable tool for clinicians to qualitatively evaluate antibiotic utilization. In skin and soft tissue infections (SSTIs), treatment strategies are tailored according to the characteristics of the infection, including purulence, necrosis, and overall severity. …