Digital Commons Network^™

Design And Evaluation Of Triazole-Pyridine Ligands For Palladium-Catalyzed C–H Activation: Exploring Traceless Directing Groups And Difluoroarene Functionalization, Angel Mercado

Electronic Theses and Dissertations Archive

C–H activation has become a pivotal strategy in organic synthesis, allowing for the direct transformation of inert carbon–hydrogen bonds into functionalized products without the need for pre-activated substrates. While directed C–H activation using coordinating directing groups (DGs) has enabled regioselective transformations, the installation and removal of DGs add extra steps and reduce synthetic efficiency. Traceless directing groups, which can be installed and removed in situ or transformed into part of the final product, offer a solution to this challenge. This dissertation explores the design, synthesis, and evaluation of novel triazole-pyridine (TriPy) ligands as potential traceless directing groups for palladium-catalyzed C–H …

Lindenwood Digest, December 18, 2024, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.

Performing Masculinities: The Assumption Of Men’S Roles By Women Left Behind By Male Migrant Labourers In Southern Tanzania, Nives Kinunda, Angelus Mnenuka, Samwel Mhajida

Journal of Humanities and Social Sciences

This article examines the empowerment of female farmers in the Southern Highlands of Tanzania due to male labour migration during the British colonial rule. The study sought to highlight the history of gender-based division of labour, the dynamics of labour division during the colonial period, the trend of females’ adoption of males’ activities, and women’s empowerment resulting from their assumption of males’ responsibilities. Data were collected through oral interviews, documentary reviews, group-focused discussions, and archival sources. The data were analysed and interpreted using a gender framework theory, which includes, among other things, gender roles and gender relations. Findings show that …

Quality Interpretation, Quality Interpretation Assessment, Back Translation, Communication Breakdown, Sense-Based Theory, Liyenja Mwinuka

Journal of Humanities and Social Sciences

This study assesses the quality of English-Kiswahili Sermon interpretation in church settings in Dar es Salaam, Tanzania, with a specific focus on the accuracy of vocabulary interpretation and its impact on effective communication between preachers and audiences. Conducted in two purposively selected Pentecostal churches, the study employed the Sense-Based Theory as its guiding framework. Data were gathered through interviews, non-participant observation, and video recordings; and were analysed qualitatively. The findings reveal frequent misinterpretation of preachers’ English vocabulary by Sermon interpreters, leading to significant communication breakdowns between preachers and their audiences. The incorrect interpretations of vocabulary were primarily attributed to the …

Memories Of Resistance To Slavery In South-Eastern Tanzania, Nancy Rushohora

Journal of Humanities and Social Sciences

This paper examines the historical representation and memory of slavery in Tanzania, arguing that the current curriculum predominantly employs a Marxist lens that emphasizes the economic dimensions of slavery while overlooking the complexity of resistance. The study’s objective is to present a more comprehensive understanding of Tanzanian slavery, focusing on forms of resistance at Mgao, a 12th–18th century Swahili site. Methodologically, this study draws on ethnographic accounts, documentary sources, and archaeological findings to uncover diverse acts of defiance, including seeking refuge, negotiating relocation, and engaging in violent confrontations. The results reveal that resistance was a widespread, multi-dimensional phenomenon in Tanzanian …

An Assessment Of Macroeconomic Effects Of Financial Liberalization In Tanzania: 1990-2022, Cornel Joseph

Journal of Humanities and Social Sciences

This study provides a comprehensive analysis of the effects of financial liberalization on key macroeconomic indicators in Tanzania, specifically focusing on savings, investment, and economic growth. Utilizing extensive annual time series data from 1990 to 2022, the research employs the Autoregressive Distributed Lag (ARDL) method and incorporates bound testing procedures to ensure robust results. The analysis reveals several significant findings: financial liberalization has a positive impact on savings and promotes economic growth in the long-run, demonstrating its role as a catalyst for economic advancement in Tanzania. However, the study also uncovers a concerning trend: while savings and growth benefit from …

Nexus Between Rural Agricultural Land Ownership And Agricultural Credits Access: A Case Of Tanzania, Gelas Rubakula

Journal of Humanities and Social Sciences

Agricultural investment in low- and middle-income countries faces credit access challenges. Several financial institutions, particularly banks, normally impose some conditions where the possession of a land title deed is required to access agricultural credits. This paper examines whether, and to what extent, rural agricultural land ownership influences agricultural credit access for rural farmers in Tanzania. The study focuses only on rural farmers and tries to find out whether these smallholder farmers can use their land, which is largely unformalized, as a collateral for credit access. The study survey was cross-sectional, using quantitative data collected in December 2017 to March 2018 …

Community, State And Professionalism: Negotiating The Experience Of Community Health Workers In The Provision Of Maternal And Child Health Services In Tanzania, Chakupewa Joseph Mpambije

Journal of Humanities and Social Sciences

Research on community health workers (CHWs) has been on the increase in the past decades in Tanzania, focusing on the provision of maternal and child health (MCH) services. While performing their tasks, CHWs work within three constructs: the community, the state, and their professionalism. However, as CHWs work within these constructs, there exists scanty literature which discourses their experiences within the realm of the community, the state and their professionalism. This review aimed to articulate how these constructs facilitate or inhibit CHWs’ performance in improving MCH services. It employed a scoping review method in which peer-reviewed articles and grey literature …

Does Market Accessibility Improve Household Food Security? Evidence From Small-Holder Maize Producers In Southern Tanzania, Monica Sebastian Kauky

Journal of Humanities and Social Sciences

This study investigated the impact of market accessibility on household food security among smallholder maize producers in Southern Tanzania, utilizing data from a sample of 407 households primarily engaged in maize farming. Tobit and probit models assessed the relationship between food security and market access. Contrary to expectations, the findings revealed no significant association between market access and food security. Instead, the results underscored the importance of resource availability, indicating that larger farm sizes and higher household wealth indices significantly reduce the risk of food insecurity. These findings suggest that rather than focusing exclusively on enhancing market access, policymakers should …

Ad Hominem Arguments In Zimbabwean Political Discourse: An Analysis Of Political Argumentation, Jack Mutsvairo, Mawande Dlali

Journal of Humanities and Social Sciences

The article investigates the motivation behind the prevalent use of the subtypes of ad hominem (personal attacks) arguments in Zimbabwe political discourse in the build-up to the 2023 harmonised council, parliamentary and presidential elections. This qualitative case study research looks at the use of ad hominem arguments by Zimbabwean politicians. Using analytical tools and concepts from informal logic and pragma-dialectical argumentation theories, this article focuses on identifying, analysing, and evaluating ad hominem arguments used in Zimbabwean political discourse, particularly in parliamentary debates and broadcast interviews. Data were purposively sampled and gathered from Hansard records, and a television interview transcript. It …

Momordicine-I Suppresses Head And Neck Cancer Growth By Modulating Key Metabolic Pathways, Debojyoty Bandyopadhyay, Ellen T Tran, Ruchi A Patel, Matthew A Luetzen, Kevin Cho, Leah P Shriver, Gary J Patti, Mark A Varvares, David A Ford, Kyle S Mccommis, Ratna B Ray

2020-Current year OA Pubs

One of the hallmarks of cancer is metabolic reprogramming which controls cellular homeostasis and therapy resistance. Here, we investigated the effect of momordicine-I (M-I), a key bioactive compound from Momordica charantia (bitter melon), on metabolic pathways in human head and neck cancer (HNC) cells and a mouse HNC tumorigenicity model. We found that M-I treatment on HNC cells significantly reduced the expression of key glycolytic molecules, SLC2A1 (GLUT-1), HK1, PFKP, PDK3, PKM, and LDHA at the mRNA and protein levels. We further observed reduced lactate accumulation, suggesting glycolysis was perturbed in M-I treated HNC cells. Metabolomic analyses confirmed a marked …

Brazilian Instrumental Music, U.S. Jazz, And Transnationalism: A Study Of National Identity In The Twentieth Century And Present, Felipe Guz Tinoco

Arts & Sciences Graduate Student Theses and Dissertations

This dissertation considers the relationship between Brazilian instrumental music, U.S. jazz, and Brazilian national identity from the early twentieth century to the present. Though the time frame is broad, the present work uses nationalism as an anchoring point through which I analyze multiple musical genres. Previous works have primarily examined songs and lyrics, particularly during the military dictatorship (1964-85), when words against the regime were censored and songwriters persecuted. However, listeners and musicians of instrumental music also engaged with discourses of national identity in profound terms before, during, and after this period, posing ideals of Brasilidade against cultural productions abroad, …

Schedulability Analysis Of Multi-Phase Limited-Preemption Tasks, Benjamin Standaert

McKelvey School of Engineering Graduate Student Theses & Dissertations

This work addresses hard real-time systems, in which tasks must be scheduled so that they are guaranteed to meet deadlines. In particular, when tasks execute across multiple domains with high preemption costs, the combined cost of these preemptions can cause the system to become unschedulable. The number of preemptions must therefore be bounded to limit the overall task execution time, while ensuring that task blocking times are small enough to allow the system to be schedulable. Prior work introduces the Multi-Phase Secure model, which describes a more exact version of this scenario, and an algorithm to determine schedulability of sporadic …

Technology Development Of High-Resolution Single-Cell Lineage Tracing For Cell Reprogramming Systems, Sadie Vanhorn

Arts & Sciences Graduate Student Theses and Dissertations

A critical element of cell identity is the cell that created the observed cell. This parent cell dictates many aspects of its identity, whether measured by function, phenotype, or specific assays. The cell’s lineage impacts the ability of the cell to differentiate into final cell types in development or successfully reprogram in direct cell reprogramming. Here, we evolve molecular barcoding techniques to increase the resolution of lineage recording at single-cell resolution. Using single-cell RNA-sequencing as the readout for this measurement, polyadenylated reporter gene transcripts with engineered 3’ untranslated regions were designed to initially label and then record lineage information. While …

Multi-Omic Analysis Of Phototrophic Extracellular Electron Uptake In Novel Rhodovulum Spp. Isolated From A Marine Estuary, Emily J. Davenport

Arts & Sciences Graduate Student Theses and Dissertations

Microbial metabolisms are incredibly versatile and dynamic, allowing adaptive strategies for growth in even the most limiting environments. For an ever-increasing number of microbes, this includes utilizing soluble or insoluble inorganic mineral species as electron donors, driving geochemical cycles and microbial metabolisms. This metabolic function of transporting electrons derived from the extracellular environment across cell membranes is called extracellular electron uptake (EEU). Within (photo)autotrophs, (p)EEU also sustains CO2 fixation to cell biomass, implicating a potentially fundamental role of microbial carbon cycling in aquatic and soil ecosystems. A model metabolic scheme of pEEU occurring in natural environments is photoferrotrophy, which pairs …

A Benchmark For Computational Analysis Of Animal Behavior, Using Animal-Borne Tags, Benjamin Hoffman, Maddie Cusimano, Vittorio Baglione, Daniela Canestrari, Damien Chevallier, Dominic L. Desantis, Lorène Jeantet, Monique A. Ladds, Takuya Maekawa, Vicente Mata-Silva, Víctor Moreno-González, Anthony M. Pagano, Eva Trapote, Outi Vainio, Antti Vehkaoja, Ken Yoda, Katherine Zacarian, Ari Friedlaender

Faculty and Staff Works

BACKGROUND: Animal-borne sensors ('bio-loggers') can record a suite of kinematic and environmental data, which are used to elucidate animal ecophysiology and improve conservation efforts. Machine learning techniques are used for interpreting the large amounts of data recorded by bio-loggers, but there exists no common framework for comparing the different machine learning techniques in this domain. This makes it difficult to, for example, identify patterns in what works well for machine learning-based analysis of bio-logger data. It also makes it difficult to evaluate the effectiveness of novel methods developed by the machine learning community. METHODS: To address this, we present the …

Higher Education Reform In Roman Catholic Ecclesiastical Institutions: Responses From French Institutions To Quality Management Imperatives, Marine Condette

Journal of Comparative & International Higher Education

No abstract provided.

Roommate Finding App Wins First Place At Business Model Competition, Angelica Owens

University of Mississippi News

OXFORD, Miss. – A new online business that connects incoming college freshmen to help them find roommates won first place during the 2024 Servin' the South Business Model Competition.

Reputation Management: Branding A Higher Education Graduate Program To Increase Visibility, Vanderbilt Artaxerxes Brabson Iv

Student Theses and Dissertations

This capstone project offers a comprehensive training tool for non-communication professionals working in higher education programs. Its main goals are to give users (1) a summary of valuable research on higher education reputation management, branding, and strategic communication, and (2) an online toolkit for non-communication professionals to boost the visibility and impact of their educational initiatives. By providing practical, actionable resources, these tools help higher education professionals effectively handle the challenges of strategic communication management. The toolkit is especially useful because it delivers evidence-based strategies and methods that can be directly applied to improve communication efforts in higher education. It …

Mild Traumatic Brain Injury In Justice-Involved Individuals And Executive Function Consequences On Transition And Reintegration Into The Community, Alaina L. Randerson

Student Capstone Papers

The United States has the highest documented incarceration rate in the world (Carson, 2022), with an increasing number of justice-involved individuals (JII) potentially affected by mild traumatic brain injury (mTBI). Despite the high prevalence of mTBIs in the general population, limited research exists on the prevalence and impact of mTBIs in JII. Preliminary evidence suggests that the prevalence of mTBIs in incarcerated individuals is 50 times higher than in the general public (Siegler et al., 2017). This study aimed to explore the lived experiences of JII with mTBI, focusing on the origin of mTBIs, executive dysfunction, and the occupational barriers …

Minutes From December 18 2024, University Senate

University Senate Minutes

Minutes from December 18 2024 University Senate Meeting

Review Of La Lingüística Hispánica: Una Introducción, Ana Peña-Oliva

Open Educational Resources - Reviews

No abstract provided.

Review Of Culturally Responsive Computing: An Introduction Into Computer Science, Security, And Technology, Irina Armianu

Open Educational Resources - Reviews

No abstract provided.

Review Of Prose Fiction: An Introduction To The Semiotics Of Narrative, Robert P. Moreira

Open Educational Resources - Reviews

No abstract provided.

Review Of College Success Concise, Erica N. Giles

Open Educational Resources - Reviews

No abstract provided.

Sensitivity Of Difficult-To-Control Palmer Amaranth Accessions To Fluridone And Diflufenican, Maria Carolina Souza, Matthew Coleman Woolard, Jason K. Norsworthy, Tristen H. Avent, Tristen H. Avent, Tom Barber, Rodrigo Botelho

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Palmer amaranth (Amaranthus palmeri S. Watson) has evolved resistance to herbicides targeting nine sites of action. Phytoene desaturase-inhibiting herbicides remain among the few sites of action that are still effective in controlling Palmer amaranth. Greenhouse experiments were conducted to evaluate the effectiveness of fluridone and diflufenican in controlling difficult-to-control Palmer amaranth accessions collected in Arkansas from 2016 to 2022, to quantify the response of three accessions that exhibited low sensitivity to both herbicides, and to evaluate the effectiveness of photosystem II inhibitors alone and with fluridone or diflufenican on three accessions. At 14 days after a preemergence application, Palmer …

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Butte Reduction Works (Brw) Phase Ii Interim Demolition Plan Construction Drawings And Floodplain Encroachment Analysis (Dated November 27, 2024), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

A Critical Discourse Analysis Of The Representation Of Gender Images In Wedding Speeches In Tanzania, Reuben Ndimbo, Antoni Keya

Journal of Humanities and Social Sciences

This study examined parents’ counsel during weddings to determine how wedding discourse represents gender relations. This article utilized a qualitative methodology, using audio-visual records of speeches and the focus group discussion technique to gather data. Using critical discourse analysis, the study found that wedding discourse reinforces stereotypical gender roles following the dominant male ideology, portraying men as the supreme heads of households who are responsible for making important decisions, including financial and political matters. On the other hand, women are projected as obedient, showing humility: perpetuating the image of dependent and submissive individuals. The study provides a basis for linguistic …

Transforming Growth Factor-Beta Is Increased In Sputum From Individuals With Rheumatoid Arthritis-Associated Pulmonary Fibrosis, Timothy M. Wilson, Matthew Bolt, Andrew Stahly, Joyce S. Lee, Tami J. Bang, Peter B. Sachs, Kevin D. Deane, Stephen M. Humphries, Joshua J. Solomon, M. Kristen Demoruelle

Division of Rheumatology Faculty Papers

BACKGROUND: Interstitial lung disease (ILD) develops in 5-10% of patients with RA and contributes significantly to morbidity and mortality, particularly in those with a fibrotic phenotype. Yet, biomarkers to reliably identify RA patients with underlying pulmonary fibrosis are inadequate. Herein, we used sputum to identify lung-based biomarkers that distinguish RA patients with underlying pulmonary fibrosis and may better inform underlying pathogenesis in RA-ILD.

METHODS: We included 37 RA patients with pulmonary fibrosis (RA-PF) and 30 RA patients without ILD (RA-no-ILD). Induced sputum and serum were tested for TGF-β levels by immunoassay. DNA was extracted to determine presence of the MUC5B …

Factors Affecting Sport-Related Concussion Non-Disclosure In Women's Rugby-A Multi-Country Qualitative Analysis, Lisa Ryan, Ed Daly, Katherine Hunzinger

Department of Exercise Science Faculty Papers

Background and Objectives: Collision-sport athletes, such as rugby players, are at risk of sport-related concussion (SRC). Women are known to be at higher risk of SRC and may experience more severe and chronic symptomology than men. Knowledge of the factors that affect a player’s disclosure of their concussive symptoms could help to inform strategies to improve compliance with reporting and management of head injuries. The aim of this study was to investigate the factors that may impact women rugby players’ disclosure of a concussion. Methods: Twenty-eight adult (≥18 years of age) elite and semi-elite women rugby players from the UK …