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2024

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Lldpe Film Development Surface With Nucleating Agents To Reduce Fat Stains From Food Adherence On The Film Surface For Easy Rinsing Before Recycling, Nattapong Pinpru, Chiranicha Ninthap, Supang Sripraphot, Supharada Khaisaat Jan 2024

Lldpe Film Development Surface With Nucleating Agents To Reduce Fat Stains From Food Adherence On The Film Surface For Easy Rinsing Before Recycling, Nattapong Pinpru, Chiranicha Ninthap, Supang Sripraphot, Supharada Khaisaat

Journal of Metals, Materials and Minerals

The purpose of this research was to enhance the surface of linear low-density polyethylene (LLDPE) film by using single and hybrid nucleating agents to reduce fat stains from food adherence on the film surface for easy rinsing before recycling, consequently reducing energy consumption before recycling. The process begins with the preparation of a high-concentration masterbatch of LLDPE with nucleating agents and polyethylene glycol (PEG), followed by blown film and test analysis. The results showed that both single and hybrid nucleating agents resulted in substantial modifications in the surface characteristics of the film. The altered surface texture of the film makes …


Fast Microwave Synthesis Of High-Silica Natural Soil Based Porous Geopolymer, Naritsara Toobpeng, Sirithan Jiemsirilers Jan 2024

Fast Microwave Synthesis Of High-Silica Natural Soil Based Porous Geopolymer, Naritsara Toobpeng, Sirithan Jiemsirilers

Journal of Metals, Materials and Minerals

This study describes a simple microwave process for fabricating porous geopolymer-polymer based Shirasu soil. The porous geopolymer samples were synthesized using sodium silicate (Na2SiO3) and sodium hydroxide (NaOH) solution as alkaline solution in range of 0.5 M to 9 M. After mixing process, the geopolymer slurry was heated and stimulated geopolymerization reaction by different microwave powers at 200 W, 500 W and 700 W for 30 s, 60 s, 90 s and 120 s. The influence of NaOH concentration, microwave powers and heating times on the apparent bulk density, the water adsorption was focused. Results showed that the microwave powers …


Investigating The High-Impact Deformation Behavior Of Induced-Nano Precipitation Hardened In718 Alloy, Harrison Okechukwu Onovo, Muideen Adebayo Bodude, David Ehigie Esezobor, Thaddeus Tochukwu Akano Jan 2024

Investigating The High-Impact Deformation Behavior Of Induced-Nano Precipitation Hardened In718 Alloy, Harrison Okechukwu Onovo, Muideen Adebayo Bodude, David Ehigie Esezobor, Thaddeus Tochukwu Akano

Journal of Metals, Materials and Minerals

Superalloys are the preferred materials for modern high-rotational complex components due to their exceptional ability to maintain critical properties such as strength, oxidation/corrosion resistance, even under extreme temperatures and dynamic impacts. This study investigates the dynamic impact response of nanoprecipitation-hardened 718 alloy (NPH-718 alloy) under various loading conditions. The wrought nickel-based NPH-718 alloy was transformed into a nanostructured state through a precise heat treatment process involving controlled cooling rates (28℃∙s‒1 to 30℃∙s‒1). A mechanical compression test, leading to failure, was employed to assess the alloy's ability to withstand dynamic impacts. The compressive dynamic behavior of the alloy at high strain …


Atmospheric Hydrochloric And Nitric Acid Leaching Of A Limonite Ore From The Wolo Mine Area, Southeast Sulawesi, Indonesia, Sufriadin -, Malyanus Yepta, Irzal Nur, Purwanto -, Rizky Amalia, Ulva Ria Irfan, Djabal Nur Basir, Tsubasa Otake Jan 2024

Atmospheric Hydrochloric And Nitric Acid Leaching Of A Limonite Ore From The Wolo Mine Area, Southeast Sulawesi, Indonesia, Sufriadin -, Malyanus Yepta, Irzal Nur, Purwanto -, Rizky Amalia, Ulva Ria Irfan, Djabal Nur Basir, Tsubasa Otake

Journal of Metals, Materials and Minerals

The atmospheric acid leaching studies of a limonite ore sample from the Wolo mine area, Southeast Sulawesi, Indonesia, have been performed using hydrochloric acid (HCl) and nitric acid (HNO3). The objectives of these studies were to compare the leaching degree of metals (Ni, Co, Fe, and Al) and to analyze the dissolution behavior of minerals under different acid concentrations. Mineralogical characterization of the ore sample was conducted using optical microscopy, scanning electron microscopy (SEM), and X-ray diffraction, whereas chemical composition was determined by X-ray fluorescence (XRF) spectrometry and atomic absorption spectroscopy (AAS), respectively. An atmospheric leaching test was done with …


In Vitro And Vivo Biocompatibility And Degradability Of Low-Alloyed Mg-Zn-Ca-Mgo Composite As Bone Repair Biomaterials, Shuquan Zhang, Jiangtao Feng, Chaokun Tang, Ran Pang, Xinglong Zhang, Chenguang Li, Weihao Zhang, Fengxin Zhou, Feng Xue, Shaoyuan Lyu, Minfang Chen, Hao Wang Jan 2024

In Vitro And Vivo Biocompatibility And Degradability Of Low-Alloyed Mg-Zn-Ca-Mgo Composite As Bone Repair Biomaterials, Shuquan Zhang, Jiangtao Feng, Chaokun Tang, Ran Pang, Xinglong Zhang, Chenguang Li, Weihao Zhang, Fengxin Zhou, Feng Xue, Shaoyuan Lyu, Minfang Chen, Hao Wang

Journal of Metals, Materials and Minerals

Magnesium alloys have gained attention as biodegradable bone repair biomaterials. Unlike non-biodegradable materials like titanium and tantalum, biodegradable implants offer advantages in promoting bone healing and minimizing chronic inflammatory reactions. However, the impact of the implant's degradation on the osteogenic environment remains a concern. The Mg-Zn-Ca-MgO composite, being biocompatible and containing osteogenic ions, is a promising candidate. This study assesses the degradability and in vitro/in vivo biocompatibility of two Mg-Zn-Ca-MgO composites with varying degradation rates. The Mg-1Zn-0.2Ca-1.0MgO composite was prepared, and leaching solutions were created following standard protocols. MC3T3-E1 cell cultures were conducted to assess cell toxicity, alkaline phosphatase (ALP) …


Aku Libraries Annual Report - 2024, Office Of The University Librarian Jan 2024

Aku Libraries Annual Report - 2024, Office Of The University Librarian

Office of the University Librarian Reports

- Message by Peter Gatiti Associate Vice Provost & University Librarian

- Celebrating AKU Scholars

- AKU Author’s Day – 2024

- ISMC – London UK Writing People's Histories

- Author’s Day – Other events in Karachi

- Psychoanalytic Sociology: A New Theory of the Social Bond

- Secret Santa Book Exchange!

- IED’s Baatein Kitab Ki – In conversation with Senator (r) Javed Jabbar

- Conversation with Dr. Iftikhar Salahuddin

- Recent Best Practices in Publishing

- Library news from around our Campuses

- RFID Technology in AKU Libraries

- Information Literacy

- Conferences & Workshops

- Book Launches …


Institute For Global Health And Development : Annual 2024, Institute For Global Health And Development Jan 2024

Institute For Global Health And Development : Annual 2024, Institute For Global Health And Development

IGHD Newsletters

  • Message From The Director
  • Workshops & Conferences
  • Climate Change, Agriculture, Human Nutrition & Development in Pakistan
  • What Works Climate Solutions Summit, Berlin
  • IGNIT3 Consultative Workshop on Nutrition for Health Professionals
  • Climate Change and Health Symposium
  • Collaborating For Change
  • IGHD Hosts Workshop on Research Concepts & Basic Methodology
  • SDSN Pakistan Leadership Council Meeting – 2024
  • AKDN Technical Working Group (TWG) Meeting 2024
  • Projects In the Spotlight
  • Shining Light On Achievement
  • Education And Capacity Building
  • Team Building Activities
  • Research Insights


Developing A Framework For Musical Ekphrasis In Jazz Composition, Jessica Carlton Jan 2024

Developing A Framework For Musical Ekphrasis In Jazz Composition, Jessica Carlton

Theses: Doctorates and Masters

Musical ekphrasis, as defined by musicologist Siglind Bruhn (2001), refers to musical compositions that transform, re-create, or ‘re-present’ a work of visual art or poetry. Though there exists a significant body of musical works that are based on visual art and poetry, there is a distinct lack of research and documentation on musical ekphrasis, particularly in the field of jazz and improvised music. Further, a formalised process framework for practitioners approaching ekphrastic composition has yet to be developed. This research project investigated musical ekphrasis through qualitative interviews with key practitioners, and a combination of practice-led research and research-led practice methodologies, …


The Commonwealth Of Amnesia: A Collection Of Erasure And Cut-Up Poems Exploring The Forgotten Histories Of Croatian And Yugoslav Peoples In Australia And An Exegesis Obliteration Creates More: Examining The Wreck Of History Through Whiteout, Blackout And Cut-Up Erasure Poetry, Natalie Damjanovich-Napoleon Jan 2024

The Commonwealth Of Amnesia: A Collection Of Erasure And Cut-Up Poems Exploring The Forgotten Histories Of Croatian And Yugoslav Peoples In Australia And An Exegesis Obliteration Creates More: Examining The Wreck Of History Through Whiteout, Blackout And Cut-Up Erasure Poetry, Natalie Damjanovich-Napoleon

Theses: Doctorates and Masters

This thesis consists of two parts, a collection of poems, “The Commonwealth of Amnesia”, and an accompanying exegesis. The collection explores the forgotten histories of Croatian and Yugoslav immigrants in Australia from 1901 to 1957 through the medium of erasure and cut-up poetry, re-arranging words found in nonfiction documents to posit that forgetting can be metaphorically and visually represented through erasure while also re-narrativising a text. Erasure poetry takes a textual document and using whiteout or blackout erases portions of a text, transforming that text into a poem; cut-up poetry rearranges the words of a document in a textual version …


A Tale Of The Well-Ness Monster: Examining The Mental Wellness Needs Of Pre-Service Teachers During The Assistant Teacher Program, Carli Sanbrook Jan 2024

A Tale Of The Well-Ness Monster: Examining The Mental Wellness Needs Of Pre-Service Teachers During The Assistant Teacher Program, Carli Sanbrook

Theses: Doctorates and Masters

Pre-service teachers experience many stressors while undertaking their undergraduate degree. These include course related stressors such as academic struggles, financial pressures surrounding outside employment to fund studies, and personal stressors with partners, family and friends exacerbated by coursework pressures. Furthermore, the practicum is known to amplify the effect of these stressors on pre-service teachers because of the time intense commitment involved. Stress, both internally generated or externally imposed, is detrimental to mental wellness and can ultimately impact pre-service teacher effectiveness.

The aim of this research project was to examine pre-service teachers' mental wellness needs by focusing on the Assistant Teacher …


Parental Involvement In Children's Writing, Bronte Peta Kelso-Marsh Jan 2024

Parental Involvement In Children's Writing, Bronte Peta Kelso-Marsh

Theses: Doctorates and Masters

Research suggests that parental involvement is important for supporting children’s early literacy development. However, much of the existing research has focused on reading outcomes, and studies have seldom examined the influence of parental involvement on children’s writing outcomes. Learning to write is a complex process. Furthermore, although writing is a necessary skill required throughout schooling and the workforce, evidence from international studies suggests children’s writing performance is in decline. Theoretical models of writing have proposed the importance of contextual factors in shaping children’s writing acquisition and development, which may include parents. However, whilst previous research suggests parental involvement in supporting …


Care-Full Climate Justice Organising: Movement-Based Participatory Action Research On Noongar Boodja, Kylie A. Wrigley Jan 2024

Care-Full Climate Justice Organising: Movement-Based Participatory Action Research On Noongar Boodja, Kylie A. Wrigley

Theses: Doctorates and Masters

Aligned with emerging research agendas for critical (intersectional and decolonial) climate justice, this research aims to co-create place-based knowledges and actions about how communities and movements organise for climate justice. Organising for climate justice in Western Australia (WA) is particularly difficult because of the strong influence of the fossil fuel industry and the prevailing racial capitalist, colonial, and patriarchal responses to climate change in policy and mainstream climate movements. These systems of power often reproduce, for example, intersecting gender, race, and class inequalities, which marginalise communities most impacted by climate injustice. Moreover, many climate activists experience climate distress and burnout. …


Diagnosing Innovation: A Design-Led Approach To Cultivate Innovation In The Western Australian Public Health System, Sash Milne Jan 2024

Diagnosing Innovation: A Design-Led Approach To Cultivate Innovation In The Western Australian Public Health System, Sash Milne

Theses: Doctorates and Masters

Recent research highlights the significance of design-led approaches, such as human-centred design, in fostering an innovative culture within complex public systems like public health. However, transforming systemic culture on a large scale presents a formidable challenge, constituting its own "wicked problem" that is both a fertile ground for design intervention and exceptionally difficult to tackle.

My research employs a design-led research perspective to investigate the current state of innovation culture within WA Health and to identify potential leverage points for future cultural transformation. Utilising data gathered from interviews and workshops, this research project sheds light on the multifaceted barriers confronting …


The Impact Of Reported Antibiotic Allergy In Paediatric Care And Antimicrobial Stewardship, Annabelle Arnold Jan 2024

The Impact Of Reported Antibiotic Allergy In Paediatric Care And Antimicrobial Stewardship, Annabelle Arnold

Theses: Doctorates and Masters

Antimicrobial resistance is rising while new drug development declines, making antimicrobial stewardship crucial for optimizing use, preventing resistance, and improving patient outcomes. Antibiotics are vital for bacterial infections, but overuse and inappropriate prescribing have contributed to resistance. Although 5-35% of the global population reports β-lactam allergies, over 90% of reports are inaccurate. Adults have the highest prevalence; however, these labels are often acquired in childhood, with a notable increase among children recently. Unverified allergy labels hinder antimicrobial stewardship, leading to longer hospital stays, alternative prescribing, and a higher risk of adverse events.

This thesis sought to evaluate current evidence regarding …


Crop Yield Using Novel Parametric L-System Plant Modelling, Christopher Cameron Napier Jan 2024

Crop Yield Using Novel Parametric L-System Plant Modelling, Christopher Cameron Napier

Theses: Doctorates and Masters

This research considers a system for the recognition of real plant parts through image analysis based upon synthetic plant modelling. It aims to use data pipelines and synthetic datasets to define recognizable features that assist in the efficient analysis of real plants and plant images. This research asks about the efficacy of L-systems in accurately simulating wheat crop characteristics. It specifically focusses on readable, understandable, accurate, and complex L-system algorithms. The research examines wheat crops in terms of phenotypes and examines the accuracy of a dataset in support of real image annotation. The methodology used was experimental in nature and …


The Development, Implementation And Evaluation Of A Novel Intervention For Delirium Prevention And Management In An Adult Intensive Care Unit: A Mixed Methods Study, Gideon Ugochukwu Johnson Jan 2024

The Development, Implementation And Evaluation Of A Novel Intervention For Delirium Prevention And Management In An Adult Intensive Care Unit: A Mixed Methods Study, Gideon Ugochukwu Johnson

Theses: Doctorates and Masters

Background: Delirium is a prevalent acute brain dysfunction in patients within intensive care units. Delirium is marked by a fluctuating mental state, inattention, and altered consciousness. This condition affects a substantial proportion of patients in intensive care units, and which leads to increased mortality, severe physiological and psychological consequences, and a significant economic burden on healthcare systems. Despite the evidence that supports the use of non-pharmacological interventions to prevent or minimise the impact of delirium such as orientation, sensory stimulation, early mobilisation, and family involvement, their implementation in intensive care units remains inconsistent. The involvement of family members in the …


The Meme Stock Fenzy: Origins And Implications, Dhruv Aggarwal, Albert H. Choi, Yoon-Ho Alex Lee Jan 2024

The Meme Stock Fenzy: Origins And Implications, Dhruv Aggarwal, Albert H. Choi, Yoon-Ho Alex Lee

Articles

In 2021, several publicly traded companies, such as GameStop, Bed Bath & Beyond, and AMC, became “meme stocks,” experiencing a sharp rise in their stock prices through a dramatic influx of retail investors into their shareholder base. Analyses of the meme stock surge and its implications for corporate governance have focused on the idiosyncratic creation of online communities around particular stocks during the COVID-19 pandemic. In this Article, we argue that the emergence of meme stocks is part of longer-running and more structural digital transformations in trading, investing, and governance. On the trading front, the abolition of commissions by major …


Research Access To Social Media Data: Lessons From Clinical Trial Data Sharing, Christopher J. Morten, Gabriel Nicholas, Salomé Vilgoen Jan 2024

Research Access To Social Media Data: Lessons From Clinical Trial Data Sharing, Christopher J. Morten, Gabriel Nicholas, Salomé Vilgoen

Articles

For years, social media companies have sparred with lawmakers over how much independent access to platform data they should provide researchers. Sharing data with researchers allows the public to better understand the risks and harms associated with social media, including areas such as misinformation, child safety, and political polarization. Yet researcher access is controversial. Privacy advocates and companies raise the potential privacy threats of researchers using such data irresponsibly. In addition, social media companies raise concerns over trade secrecy: the data these companies hold and the algorithms powered by that data are secretive sources of competitive advantage. This Article shows …


Rethinking Innovation At Fda, Rachel E. Sachs, Nicholson Price, Patricia J. Zeitler Jan 2024

Rethinking Innovation At Fda, Rachel E. Sachs, Nicholson Price, Patricia J. Zeitler

Articles

In several controversial drug approval decisions in recent years, the Food & Drug Administration (“FDA”) has publicly justified its decision partly on the ground that approving the drugs in question would support innovation in those fields going forward. To some observers, these arguments were surprising, as the Agency’s determination whether a drug is “safe” and “effective” does not seem to depend on whether its approval also supports innovation. But FDA’s use of these innovation arguments in drug approval decisions is just one example of the ways in which the Agency has come to make many innovation-related judgments as part of …


Sins And Omissions: Slavery And The Bill Of Rights, Richard Primus Jan 2024

Sins And Omissions: Slavery And The Bill Of Rights, Richard Primus

Articles

According to the conventional story, the Constitutional Convention declined to include a bill of rights in the Constitution because it trusted the enumeration of congressional powers to do the necessary work of limiting the federal government. That conventional story is historically unfounded. It is not supported by contemporary evidence, and it was roundly disbelieved at the time. Although it is not possible to know for certain why (really, for what mix of reasons) the Framers omitted a bill of rights, it seems likely that one major reason was that formulating a bill of rights would have provoked a bitter fight …


Meme Corporate Governance, Dhruv Aggarwal, Albert H. Choi, Yoon-Ho Alex Lee Jan 2024

Meme Corporate Governance, Dhruv Aggarwal, Albert H. Choi, Yoon-Ho Alex Lee

Articles

Can retail investors revolutionize corporate governance and make public companies more responsive to social concerns? Beginning in 2021, there was a dramatic influx of retail investors into the shareholder base of “meme” stock companies such as GameStop, AMC, and Bed Bath & Beyond. Observing the unprecedented, coordinated trading among retail investors, scholars and practitioners predicted that the influx of retail investors would reduce the power of large institutional investors and democratize corporate governance. These predictions were driven by three factors: generational, with assumptions that millennial and Gen Z investors would challenge corporate management; societal, reflecting growing discontent with slow progress …


21st-Century Environmental Challenges And Revitalizing Epa Enforcement, David Uhlmann Jan 2024

21st-Century Environmental Challenges And Revitalizing Epa Enforcement, David Uhlmann

Articles

This is a profound moment for environmental protection efforts in our country. Over the past half-century, under presidents of both parties, we have made great progress addressing the challenges that led to the enactment of our environmental laws during the 1970s. Our air is cleaner, our rivers and streams are healthier, and we have far fewer hazardous waste sites. We have achieved those successes because of conscientious companies across America who meet their environmental obligations and the vigilance of the U.S. Environmental Protection Agency (EPA) and the Justice Department when companies break the law and put their profits before the …


Applying Strict Scrutiny In Termination Of Parental Rights Proceedings: Why Alabama’S Jurisprudence Should Reshape Child Protection Practice, Christopher Church, Vivek Sankaran Jan 2024

Applying Strict Scrutiny In Termination Of Parental Rights Proceedings: Why Alabama’S Jurisprudence Should Reshape Child Protection Practice, Christopher Church, Vivek Sankaran

Articles

“Our decision in [Pierce] holds that parents have a fundamental constitutional right to rear their children . . . . I would apply strict scrutiny to infringements of fundamental rights.” “[S]trict scrutiny leaves few survivors.” Termination of parental rights (TPR) stands as “a unique kind of deprivation” that results in the state irrevocably severing a parent’s fundamental right to care for their child. In The Ties that Bind Us, we scrutinized the child protection system’s overuse of TPR, employing clinical, empirical, and constitutional perspectives. This Article advocates for a constitutionally anchored framework aimed at enforcing strict scrutiny when considering TPR …


Taxation And Corporate Governance, Reuven S. Avi-Yonah, Ariel Siman Jan 2024

Taxation And Corporate Governance, Reuven S. Avi-Yonah, Ariel Siman

Articles

Legal and economic scholars have examined the intersection between corporate governance and taxation; however, recent legal scholarship has generally focused on the interplay between director compensation, management measures in the face of the market for corporate control, and the double taxation of inter-corporate dividends. Other aspects of the relationship between corporate governance and taxation have received limited attention. This article aims to fill this gap in the literature. First, this paper discusses the corporate agency problem and the existing justifications for the corporate tax. Second, this paper argues that the corporate tax can be justified on the ground that it …


Cognitive Dissonance In The Antebellum South About The Lawfulness Of Slavery, Peter K. Westen Jan 2024

Cognitive Dissonance In The Antebellum South About The Lawfulness Of Slavery, Peter K. Westen

Articles

The institution of slavery, by its nature, was necessarily grounded in law. For whenever a society adjudges one class of persons as free and another as enslaved, law-like norms must exist to identify and distinguish the free from the enslaved. And whenever a society institutionalizes slavery, law-like norms must exist to establish the privileges and disabilities possessed by masters, by the enslaved, and by third persons in relation to masters and slaves. Such master-slave norms may not always be enforced. But, until societies disavow or disremember them, they constitute standards of right and wrong that master-slave societies profess to embrace. …


Whither Lob?, Reuven S. Avi-Yonah Jan 2024

Whither Lob?, Reuven S. Avi-Yonah

Articles

On January 1, 2024, the 1979 tax treaty between the United States andHungary was officially terminated.A revised treaty was signed in 2010but was never ratified by the United States, and it is unlikely that it willcome into effect any time soon.This situation is an anomaly because the United States has tax treaties withmost other members of the European Union (EU) and the Organisation forEconomic Co-operation and Development (OECD). Why did the UnitedStates terminate the treaty in July 2022?


The Joy Of The Fight: What Litigators Can Learn From The Martial Arts, Len Niehoff, Tim Lynch Jan 2024

The Joy Of The Fight: What Litigators Can Learn From The Martial Arts, Len Niehoff, Tim Lynch

Articles

You walk into a martial arts training studio (in Japanese styles, a dojo) and you scan the room. Everything going on here looks, well, unpleasant. In one corner, you observe a group of students performing kata, choreographed sequences of kicks, punches, and blocks that simulate the experience of fighting multiple opponents. Sweat pours off them. In another corner, you see two students engaged in sparring exercises, or kumite. The sharp, smacking noise of one student striking the protective pads worn by another carries across the room. In a third corner, you notice students doing push-ups, working their muscles until their …


Brief Of A Former Federal Judge, Fair And Just Prosecution, 17 Law Professors, And 4 Domestic Violence Researchers And Advocates As Amici Curiae In Support Of Petitioner, Jamie Abrams Jan 2024

Brief Of A Former Federal Judge, Fair And Just Prosecution, 17 Law Professors, And 4 Domestic Violence Researchers And Advocates As Amici Curiae In Support Of Petitioner, Jamie Abrams

Amicus Briefs & Court Filings

While amici are not formally affiliated with each other and come from a variety of professional fields, they are all keenly aware of the pernicious effects of gender bias against female defendants in American courtrooms. Each is deeply familiar with the toll that gender bias exacts not only on the individual women whose interactions with the criminal legal system are tainted by it, but also on the quality, reliability, and fairness of the criminal legal system. Together they have a distinct interest in ensuring that inflammatory and prejudicial gendered stereotypes about how women should look, act, and comport themselves are …


The Molecular Landscape Of Sepsis Severity In Infants: Enhanced Coagulation, Innate Immunity, And T Cell Repression, Susie Shih Yin Huang, Mohammed Toufiq, Pirooz Eghtesady, Nicholas Van Panhuys, Mathieu Garand Jan 2024

The Molecular Landscape Of Sepsis Severity In Infants: Enhanced Coagulation, Innate Immunity, And T Cell Repression, Susie Shih Yin Huang, Mohammed Toufiq, Pirooz Eghtesady, Nicholas Van Panhuys, Mathieu Garand

2020-Current year OA Pubs

INTRODUCTION: Sepsis remains a major cause of mortality and morbidity in infants. In recent years, several gene marker strategies for the early identification of sepsis have been proposed but only a few have been independently validated for adult cohorts and applicability to infant sepsis remains unclear. Biomarkers to assess disease severity and risks of shock also represent an important unmet need.

METHODS: To elucidate characteristics driving sepsis in infants, we assembled a multi-transcriptomic dataset from public microarray datasets originating from five independent studies pertaining to bacterial sepsis in infant < 6-months of age (total n=335). We utilized a COmbat co-normalization strategy to enable comparative evaluation across multiple studies while preserving the relationship between cases and controls.

RESULTS: We found good concordance with only two out of seven …


Empowering Providers To Empower Their Patients: One Model To Expand Knowledge, Competency, And Awareness For The Perinatal Substance Use Workforce, Jacqueline Jacobs Jan 2024

Empowering Providers To Empower Their Patients: One Model To Expand Knowledge, Competency, And Awareness For The Perinatal Substance Use Workforce, Jacqueline Jacobs

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Perinatal substance use (PSU) is a serious and growing public health concern. It is associated with a variety of adverse health outcomes for both mother and child and has been shown to negatively impact the parent-child relationship. Despite the growing prevalence of PSU, there are notable deficits in provider knowledge regarding, and comfortability with, PSU. Moreover, providers report feelings of judgment, resentment, fear, and hesitancy related to their work with women with PSU. Subsequently, women with PSU struggle to find appropriate, compassionate, and effective treatment for their substance misuse. Widespread and accessible training is needed to bolster provider knowledge base, …