Digital Commons Network^™

Understanding Sextupole, T. Zolkin, I. Morozov, S. Nagaitsev

Physics Faculty Publications

In this study, we reassess the dynamics within a simple accelerator lattice featuring a single degree of freedom and incorporating a sextupole magnet. In the initial segment, we revisit the Hénon quadratic map, a representation of a general transformation with quadratic nonlinearity. In the subsequent section, we unveil that a conventional sextupole is essentially a composite structure, comprising an integrable McMillan sextupole and octupole, along with non-integrable corrections of higher orders. This fresh perspective sheds light on the fundamental nature of the sextupole magnet, providing a more nuanced understanding of its far-from-trivial chaotic dynamics. Importantly, it enables the description of …

Inclusive Reactions From Finite Minkowski Spacetime Correlation Functions, Marco A. Carrillo, Raúl A. Briceño, Alexandru M. Sturzu

Physics Faculty Publications

The need to determine scattering amplitudes of few-hadron systems for arbitrary kinematics expands a broad set of subfields of modern-day nuclear and hadronic physics. In this work, we expand upon previous explorations on the use of real-time methods, like quantum computing or tensor networks, to determine few-body scattering amplitudes. Such calculations must be performed in a finite Minkowski spacetime, where scattering amplitudes are not well defined. Our previous work presented a conjecture of a systematically improvable estimator for scattering amplitudes constructed from finite-volume correlation functions. Here we provide further evidence that the prescription works for larger kinematic regions than previously …

Conformal Bk Equation At Qcd Wilson-Fisher Point, I. Balitsky, G. A. Chirilli

Physics Faculty Publications

High-energy scattering in pQCD in the Regge limit is described by the evolution of Wilson lines governed by the BK equation [1, 2]. In the leading order, the BK equation is conformally invariant and the eigenfunctions of the linearized BFKL equation are powers. It is a common belief that at d ≠ 4 the BFKL equation is useless since unlike d = 4 case it cannot be solved by usual methods. However, we demonstrate that at critical Wilson-Fisher point of QCD the relevant part of NLO BK restores the conformal invariance so the solutions are again powers. As a check …

Irreconcilable: Mcdonnell Douglas And Summary Judgment, Sandra F. Sperino

Faculty Publications

The McDonnell Douglas framework is the most important analytical structure in employment discrimination law. Scholars and judges have regularly criticized the three-part burden-shifting test. Despite decades of criticism, a central feature of the framework remains unexamined - its second step is incompatible with the summaryjudgment standard.

In employment discrimination cases courts often grant summaryjudgment in the employer's favor. Scholars have offered various accounts of why this happens, including docket pressures and published case law that focuses on grants of summary judgment. The second step of the inquiry has largely escaped scrutiny because it appears to be a quirky, but somewhat …

F₀(1370) And F₀(980) Controversies From Dispersive Data Analyses, Jose R. Pelaez, A. Rodas, J. Ruiz De Elvira

Physics Faculty Publications

We report on our recent works on dispersive analyses of ππ → ππ and ππ → K ¯ K scattering data and their use to address two controversial aspects of the f₀(1370) and f₀(980) scalar mesons. First, we show with model-independent techniques that the f₀(1370) pole does indeed appear in meson–meson scattering data, although there is tension between its values in the ππ and K ¯ K channels. Second, we explain the proper interpretation of the f₀(980) pole residue, which would otherwise lead to branching ratios larger than one. We have also provided simple ππ → ππ data parameterizations that …

Investigation Of L-Serine Synthesis And Transport As Stabilizing Feedback Mechanisms Within The Tsetse-Wigglesworthia Symbiosis, Ryan Phillips

Graduate Theses, Dissertations, and Problem Reports (ETD)

Tsetse flies (Glossina morsitans), which are the obligate vectors of Old-World trypanosomes (Trypanosoma spp.) that cause African trypanosomiasis, have a bacteriome that houses the intracellular endosymbiont Wigglesworthia glossinidia. The ancient coevolution of these species has led to the integration of Wigglesworthia metabolism into tsetse physiology and a subsequent reliance on nutrient exchange for maintaining the fitness of both partners. The establishment of this obligate mutualism has facilitated the emergence of feedback mechanisms that stabilize the symbiosis, such as that which involves the exchange of L-serine and B vitamins. The Gammaproteobacteria Wigglesworthia supplement B vitamins lacking …

Breaking The Vicious Cycle Fragmenting National Law, Ryan Vacca, Peter S. Menell

Faculty Publications

One of the most troubling and increasingly overlooked problems plaguing the federal judiciary has been the reduction of throughput at the Supreme Court and the resulting fragmentation of national law. The imperative to resolve circuit splits has taken a back seat as the Court grapples with high-profile battles and the relentless crush of certiorari petitions. This fuels confusion and greater fragmentation of national law. Add in the general expansion of national law, and the vicious cycle intensifies.

This Article proposes a solution for expanding structural capacity to address fragmentation that does not require legislative reform or constitutional amendment. It utilizes …

Individualized Ideological Enclosures: The Generative Ai Crisis And How Consumers Can Reclaim Their Feeds, Sydney Rose

Catholic University Journal of Law and Technology

No abstract provided.

Targeting Pyruvate Metabolism Leads To Distinct Cd8+ T Cell Responses To Virus Infection And Cancer, Taewook Kang

Dartmouth College Ph.D Dissertations

CD8⁺ T cells are crucial immune cells that control viruses and cancers due to their high antigen specificity and proliferative capacity. Consequently, CD8⁺ T cells are being extensively explored in adoptive T cell therapy for cancer, autoimmune diseases, and infections in clinical and pre-clinical studies. Given that T cells rely on nutrient microenvironments and employ various nutrient processing pathways, metabolic intervention presents a promising strategy to enhance CD8⁺ T cell function and differentiation.

Pyruvate dehydrogenase (PDH) serves as a critical bifurcation point in the metabolic pathway, determining whether glucose-derived pyruvate undergoes mitochondrial oxidative phosphorylation (OXPHOS) or cytosolic …

Atomically Dispersed Zeolite-Supported Rhodium Complex: Selective And Stable Catalyst For Acetylene Semi-Hydrogenation, Yuxin Zhao, Özge D. Bozkurt, Samira F. Kurtoğlu-Öztulum, Melisa Su Yordanli, Adam S. Hoffman, Jiyun Hong, Jorge E. Perez-Aguilar, Aylin Saltuk, Deniz Akgül, Tülay Ateşin

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Highlights

• Rhodium has heretofore been known to be unselective for acetylene semi-hydrogenation.

• Electronic properties of rhodium are tuned by choice of support and metal nuclearity.

• Selectivity is maximized when Rh is atomically dispersed on a weak electron donor.

• Zeolite-supported Rh complex with C2H2 ligands offers a stable C2H4 selectivity > 90 %.

• Results demonstrate unprecedented catalytic properties of Rh for semi-hydrogenation.

Abstract

Supported rhodium catalysts are known to be unselective for semi-hydrogenation reactions. Here, by tuning the electronic structure of supported mononuclear rhodium sites determined by the metal nuclearity and the electron-donor properties of the support, we report that atomically dispersed …

From Private To Public: Lateral Transfer Student Experiences, Melissa P. Stough, Diane C. Elliott

Journal of Higher Education & Student Affairs

The phenomenon of student movement between higher education institutions has received considerable attention due to its widespread occurrence and impact on academic trajectories. While extensive research has focused on vertical transfer, such as transitions from community colleges to four-year institutions, less scrutiny has been directed towards lateral transfer, involving shifts between institutions at similar academic levels. This study aims to fill this gap by examining the factors influencing lateral transfer, specifically from private four-year colleges to public four-year institutions. The COVID-19 pandemic has heightened interest in this understudied area, with indications of increased lateral transfers in its aftermath. Leveraging data …

Fp-24-01 Long-Term Marriages Among Older U.S. Adults, 2022, Jaden Loo

National Center for Family and Marriage Research Family Profiles

No abstract provided.

Fp-24-03 A Decade Of Change In Cohabitation Across Age Groups: 2012 & 2022, Wendy D. Manning, Jaden Loo

National Center for Family and Marriage Research Family Profiles

No abstract provided.

Fp-24-06 Married Same-Sex And Different Sex Couples: A Demographic Portrait, Krista K. Westrick-Payne, Wendy D. Manning

National Center for Family and Marriage Research Family Profiles

No abstract provided.

Fp-24-11 Divorce: More Than A Century Of Change, 1900-2022, Jaden Loo

National Center for Family and Marriage Research Family Profiles

Although the divorce rate in the United States increased throughout much of the twentieth century, it has declined in recent decades. Here we explore the variation in women’s rate of divorce and the proportion of ever-married women separated/divorced from 1900 to 2022 using National Vital Statistics, Decennial Census, and American Community Survey data. We then examine the proportion of currently separated/divorced among ever-married women from 1940 to 2022, disaggregating trends by race/ethnicity and educational attainment. This profile is an update to FP-20-22 and a companion profile to FP-24-10, which details variation in marriage trends over the last century.

Investigation Of The Essential Oil Constituents Of Pimenta Racemosa Aerial Parts And Evaluation Of Its Antiviral Activity Against Hsv 1 And 2, Fathia S. Elshaarawy, Mohamed I. S. Abdelhady, Wafaa Hamdy, Haitham A. Ibrahim

Trends in advanced sciences and technology

Pimenta racemosa is a well-known plant used in traditional medicine to treat several ailments. Current pharmaceutical industries rely heavily on the discovery of secondary metabolites found in plants to aid in the development of novel drugs with potential biological activity. This study aimed to investigate the essential oil constituents of Pimenta racemose (Mill.) J. W. Moore aerial parts (leaves and small branches) and evaluate its antiviral activity. The essential oil was prepared by conventional hydro distillation method. The prepared oil was analyzed by GC/MS. Identification of the essential oil constituents was achieved by comparing retention indices (RI) relative to standard …

Impact Of Glottis Area On Airflow Dynamics In The Human Trachea Using A Simplified Stenosis Pipe Model, Amany M. Kamal, Momtaz Sedrak, Abouelmagd Abdelsamie

Trends in advanced sciences and technology

A complex transitional flow is produced in the larynx during air inhalation process, pivotal for fundamental comprehension and medical advancements in treatment methodologies. This study delves into the influence of the glottis region utilizing a simplified stenosis pipe geometry, examining two distinct cases: (1) the axisymmetric case and (2) the eccentric case. Reynolds-averaged Navier–Stokes equations with shear stress transport (SST) 𝑘 − 𝜔 turbulence model with intermittency transition activated with steady, Newtonian, and incompressible airflow have been used. The analysis underscores the significant impact of the eccentricity on the velocity by increasing 0.6% comparing with axisymmetric case, also particularly affecting …

Diabetic Insole Design Using Finite Element Analysis, Nora K. Yousef, Mohamed Tarek El-Wakad, Mohamed Ahmed Ali Eldosoky, Ahmed Mustafa Soliman

Trends in advanced sciences and technology

Diabetic patients frequently face complications such as foot ulcers which are the primary cause of lower-limb amputation. Recent research has found that reducing plantar pressure can dramatically minimize the chance of developing a diabetic foot ulcer. Using orthopedic insoles can lead to reducing and redistributing pressure on the foot's sole. The purpose of this study was to develop a technique using Finite Element Analysis (FEA) for creating dedicated, low-cost insoles for diabetic patients to reduce maximal plantar pressure, and to rapidly refine designs and assess their effectiveness in meeting a predefined pressure threshold for foot offloading in diabetic neuropathic patients. …

Examining U.S. National Trends In Adult Mental Illness And Naturalistic Psychedelic Drug Use, Daniel Grossman

All ETDs from UAB

Psychedelic drugs have gained prominent attention in recent years for their therapeutic potential in treating mental illness in clinical settings. Concurrently, population studies show increasing prevalence and notable demographic changes among naturalistic psychedelic users, as well as mixed associations between different types of naturalistic psychedelic use and mental health. However, despite this ongoing cultural shift, little is known about temporal changes in the mental health profiles of naturalistic psychedelic users at the population level. This thesis examined national trends in the association between past year naturalistic use of LSD, MDMA, and DMT/AMT/Foxy and past year mental illness among US adults, …

Erosion Of Trust In Healthcare Leadership: An Analysis Of Anomie And Social Exchange During The Covid-19 Pandemic, Ashleigh Allgood

All ETDs from UAB

Background: The COVID-19 pandemic disrupted healthcare systems worldwide, posing profound challenges for healthcare professionals. This study examined how the pandemic affected healthcare workers' trust in their leaders, comparing the acute 2021 phase and more managed 2022 period. Objective: To investigate how healthcare workers' experiences of moral distress, organizational change, belongingness, and perceived organizational support influenced trust in supervisors and senior leaders across two pandemic phases. Methods: Anonymous survey data were analyzed from healthcare professionals at a Southeastern U.S. academic medical center in 2021 (n=2,991) and 2022 (n=2,581). Ordinal logistic regression examined relationships between trust and experiences of moral distress, discrimination, …

Insulin Responses, Diet Composition, And Fat Loss, Amanda Finn

All ETDs from UAB

Some but not all studies show participants who have higher baseline insulin responses lose more weight on a low glycemic load compared to a high glycemic load diet. Most prior research tested the relationship between insulin and weight changes with only one insulin response variable, such as insulin from an orally or intravenously (IV) administered metabolic test. We tested whether insulin responses (IV or oral) predicted changes in body fat among participants undergoing diet-induced weight loss. This study was a secondary analysis of a clinical trial. In the parent study, participants were randomized to either a reduced carbohydrate (ReducedCHO) or …

Motor Development Of Individuals Referred For An Asd Evaluation, Timothy Gary Hilty

All ETDs from UAB

Autism spectrum disorder (ASD) is neurodevelopmental disorder that affects 1 in 36 children. Fine motor skill delays and deficits are a common occurrence among autistic individuals. Fine motor delays tend to present in toddlerhood and deficits tend to persist into adulthood. However, fine motor skill delays and deficits are not a component of the diagnostic criteria for an ASD diagnosis. While fine motor differences between autistic and typically developing individuals are well established, it remains unclear if these differences exist between autistic individuals and those with other neurodevelopmental disorders and whether they provide additional insight into diagnosing ASD more accurately. …

Does Ceo Education Matter? The Relationship Between Doctoral-Educated Hospital Ceos And Organizational Performance, Kofi Ali Cash

All ETDs from UAB

One of the most pressing issues in healthcare strategic leadership research is identifying which hospital chief executive officer (CEO) characteristics possess a significant and favorable relationship to organizational performance. However, little is known about the relationship between hospitals led by doctoral-educated CEOs and organizational performance. This study adds to our knowledge by examining the relationship between doctoral-educated hospital CEOs and selected financial and patient safety outcomes. UET served as the theoretical framework and guided the examination of the relationship between the selected dependent and independent variables. This study’s population included 509 acute-care hospitals across nine states, requiring a minimum four-year …

Utilization Of Romosozumab During Covid-19 Pandemic Among U.S. Medicare Beneficiaries, Ye Liu

All ETDs from UAB

Osteoporosis is increasingly recognized as a major public health issue in the aging U.S. population. Shortly after the licensure of romosozumab, an injectable medication indi-cated for women with postmenopausal osteoporosis at high risk of fracture administered by health care provider monthly, the COVID-19 pandemic broke out, which caused ma-jor disruptions to the delivery of health care across the nation. The pandemic dispropor-tionately affected minority and economically disadvantaged communities, exacerbating many pre-existing health disparities. Romosozumab has the highest dosing frequency among common injectable osteoporosis medications in the U.S. that require an office visit for injection, making romosozumab adherence more susceptible to …

Diagnostic Imaging Approaches: Pet Imaging In Monitoring Immune Responses In Oncology And Tuberculosis, Chanelle Hunter

All ETDs from UAB

Positron emission tomography (PET) imaging agents play a transformative role in personalized medicine through their application in disease diagnosis and immunotherapy monitoring, focusing on chemokine receptors, TH1-activated immune cells, and tuberculosis (TB) diagnostics. In immuno-oncology, accurately assessing TH1-activated immune cells in the tumor microenvironment (TME) is vital for evaluating cancer immunotherapy efficacy. Chemokine receptors, crucial in cellular signaling and inflammatory reactions, play a significant role in TH1 responses, thus serving as a potential area of interest in elucidating these anti-tumor responses. Through our work a novel CXCR3-targeting immunoPET probe, [89Zr]DFO-αCXCR3, was developed to detect and quantify these cells. This probe …

Titanium-45 Radiochemistry For The Development Of Pet Radiopharmaceuticals, Fnu Shefali

All ETDs from UAB

Imaging using nuclear medicine techniques has enabled non-invasive measurements of biomarkers for a wide range of diseases including cancer and neurodegenerative disorders. The production and characterization of new radioisotopes are crucial steps in designing radiopharmaceuticals for nuclear imaging applications. 45Ti is a novel radionuclide with desired physical characteristics for use in Positron Emission Tomography (PET) imaging. The half-life of 3.08 h is ideal for the imaging of small peptides. In addition, the 45Ti decay by positron emission (85 %) and a low mean positron energy (0.439 MeV) offers high spatial resolution. The production route of 45Ti is straightforward due to …

Crown Fatigue Resistance And Enamel Wear Of 3d Printed Resin Compared To Lithium Disilicate, Pranit Vasant Bora

All ETDs from UAB

Purpose: The purpose of this study is to compare the wear characteristics and fatigue resistance of two dental crown materials: SprintRay Ceramic Crown, a 3D-printed resin material, and IPS™ e.Max CAD, a lithium disilicate material. Methods: This study evaluates wear and fatigue characteristics of dental crowns made from Ceramic Crown (SprintRay) and IPS e.max CAD LT (Ivoclar). For fatigue testing, custom fatigue devices were utilized to subject the crowns to cyclic loading, simulating occlusal forces. The specimens underwent 100,000 cycle intervals until 1.5 million cycles at a load of 40N of fatigue loading, with inspections conducted for signs of debonding, …

Phosphate Drives Pulmonary Inflammation Through Fgfr1, Erk, And Akt Signaling, Seth Bollenbecker

All ETDs from UAB

Chronic kidney disease (CKD) is characterized as irreversible progressive loss of renal function and affects over one tenth of the global population. Although CKD-associated comorbidities contribute significantly to its mortality, the lungs are often not considered. Lung diseases make up three of the top six leading causes of death worldwide and share many comorbidities with CKD. Clinical reports show that CKD patients are more likely to develop obstructive and restrictive lung diseases, but the mechanisms underlying this propensity for CKD-associated pulmonary complications are unknown. Hyperphosphatemia and associated elevations of fibroblast growth factor (FGF) 23, two of many consequences of reduced …

Teachers' Perspectives On The Impact Of Interactive Read Aloud Strategies For Comprehension Skills Of Saudi Kindergarten Students: A Mixed Method Study, Riham Alsultan

All ETDs from UAB

Reading comprehension is a very integral element of encouraging lifelong learning amongst kindergarten students. The main objective of this research is to investigate teachers’ perspectives on the effectiveness of interactive read-aloud (IRA) in improving reading comprehension skills amongst kindergarten students in Saudi Arabia. The study's overarching aim was to determine how interactive reading-aloud strategies employed by Saudi kindergarten teachers during interactive read-aloud time impact Saudi kindergarten students' overall comprehension skills through the perceptions of teachers regarding the effectiveness of these strategies. To achieve this objective, the researcher employed a mixed-method research design, a combination of both quantitative and qualitative strategies. …

Predictive Modeling Using Clinical Data And Compositional Microbiome Data, Li Zhang

All ETDs from UAB

This dissertation focuses on developing predictive modeling using data from two areas: clinical data and microbiome data. Compositional data in real life are mainly represented by relative proportions. With the advancement of next-generation sequencing (NGS) technology, researchers can now collect a large volume of metagenomic sequencing data, which is valuable for investigating associations between the microbiome and host diseases. Current methods for dealing with such data are either constrained by generalization or limited by application. In the first part, to address this, we propose Bayesian compositional generalized linear models for analyzing microbiome data (BCGLM). This model incorporates a structured regularized …