Digital Commons Network^™

Predictive Value Of Preoperative Fried Frailty Phenotype Assessment And Serum Biomarkers On The Prognosis Of Elderly Patients With Femoral Neck Fracture Under General Anesthesia Within 3 Months After Surgery, Fu Xu, Xin Kuang, Baofeng Cao, Yang Yue

Turkish Journal of Medical Sciences

Background/aim: Femoral neck fracture (FNF) seriously impact the health of the elderly and affect their long-term quality of life of the patients. This study aimed to determine whether combining the preoperative Fried Frailty Phenotype (FFP) with serum fibroblast growth factor receptor 3 (FGFR3) and run-related transcription factor 2 (RUNX2) could better predict the prognosis of elderly patients with FNF 3 months after surgery.Materials and methods: A total of 150 elderly patients with FNF (60–89 years old) were enrolled and divided into a nonfrailty cohort and a frailty cohort based on preoperative FFP evaluation. The hip recovery of patients 3 months …

Comparison Of Treatment Methods In Patients With Developmental Dysplasia Of The Hip, Burhan Kurtuluş

Turkish Journal of Medical Sciences

Background/aimThe aim of this study is to compare the results of pemberton osteotomy (PO), salter innominate osteotomy (SO), open reduction (OR) and closed reduction (CR) applied in the treatment of Developmental Dysplasia of the Hip (DDH).Materials and methods101 hips of 82 patients treated at Orthopedic Clinic between 2017 and 2023 were included in the study. Preoperatively, postoperatively and at final follow-up of patients were evaluated. The results of these patients were evaluated according to Severin's radiological and Barret's clinical classifications. Patients who developed avascular necrosis (AVN) were evaluated according to the Bucholz and Ogden classification.ResultsIn terms of preoperative acetabular angle …

The Function Of P97/Valosin-Containing Protein (Vcp) And Small Vcp-Interacting Protein (Svip) In Invasion And Migration Of Pancreatic Cancer Cells, Ebru Ali̇moğullari, Sevi̇l Çayli

Turkish Journal of Medical Sciences

Background/aim: Misfolded proteins are eliminated by a process known as Endoplasmic reticulum-associated protein degradation (ERAD). ERAD has an impact on variety of illnesses, such as diabetes, cystic fibrosis, cancer, and neurological conditions. We concentrated on p97/Valosin-containing protein (VCP) and small VCP-interacting protein (SVIP) despite there being many proteins involved in ERAD. The existence and function of SVIP and p97/VCP in various types of pancreatic cancer have not yet been investigated. The study's objectives are to examine the expressions of SVIP and p97/VCP in two pancreatic cancer types and to show whether these proteins aid in the invasion and migration of …

Comparison Between Eosinophilic And Neutrophilic Asthma, Naji Ali Talib Al-Anbaky, Mohammed Waheeb Al-Obaidy

Muthanna Medical Journal

Asthma is a common respiratory disease in general population that can be further subdivided into several cellular endotypes depending on sputum cell counts. The objective of this study to conduct a comparative analysis of eosinophilic and neutrophilic asthma endotypes in terms of their respective prevalence rates, patient characteristics, severity, and treatment response. Cross-sectional study included 59 patients with asthma who attended respiratory diseases out-patient clinic in Baghdad medical hospital between October 2022 and October 2023. The study included patients between 18 and 80 years with clinical history of asthma. Sputum sample was obtained from each patient and analyzed. In a …

The Socioeconomic And Environmental Niche Of Protected Areas Reveals Global Conservation Gaps And Opportunities, David Mouillot, Laure Velez, Camille Albouy, Nicolas Casajus, Joachim Claudet, Vincent Delbar, Rodolphe Devillers, Tom B Letessier, Nicolas Loiseau, Stéphanie Manel, Laura Mannocci, Jessica Meeuwig, Nicolas Mouquet, Ana Nuno, Louise O'Connor, Valeriano Parravicini, Julien Renaud, Raphael Seguin, Marc Troussellier, Wilfried Thuiller

School of Biological and Marine Sciences

The global network of protected areas has rapidly expanded in the past decade and is expected to cover at least 30% of land and sea by 2030 to halt biodiversity erosion. Yet, the distribution of protected areas is highly heterogeneous on Earth and the social-environmental preconditions enabling or hindering protected area establishment remain poorly understood. Here, using fourteen socioeconomic and environmental factors, we characterize the multidimensional niche of terrestrial and marine protected areas, which we use to accurately establish, at the global scale, whether a particular location has preconditions favourable for paestablishment. We reveal that protected areas, particularly the most …

Marijuana Legalization And Opioid Use Disorder In Ontario, Canada, From 2015 To 2021, Luke Ome Agada

Walden Dissertations and Doctoral Studies

This study examined the trends in opioid-related hospitalizations and deaths in Ontario, Canada, from 2015, to 2021, with a particular focus on the periods before and after cannabis legalization. The social problem addressed was the ongoing opioid crisis, exacerbated by rising opioid-related health issues. Grounded in the harm reduction theory, this research explored whether cannabis legalization could serve as a substitute to mitigate opioid use disorder. Data were extracted from the Discharge Database, Emergency Department Database, National Ambulatory Care Reporting System, and Hospital Morbidity Database. Analysis using the generalized estimation equation (GEE) method revealed a significant increase in opioid-related hospitalizations, …

Exploration Of General Education Teachers’ Self-Efficacy Regarding Inclusive Teaching Strategies In A West African School, Susan Regina Robinson

Walden Dissertations and Doctoral Studies

Limited research has existed regarding general education teachers’ perception of self-efficacy in teaching in the inclusive classroom in Central Ghanaian schools where performance outcomes fall below government standards. The purpose of this qualitative study was to examine general education teachers’ perceptions of self-efficacy regarding the implementation of inclusive teaching strategies at a Central Ghanaian school. Bandura’s social cognitive theory was the conceptual framework of this study. The research questions focused on teachers’ perception of self-efficacy in the implementation of instruction in the inclusive classroom and whether professional development was essential to their capacity to implement inclusive instruction. For this basic …

Association Of Coronary Endothelial Function And Angiotensin Receptor Autoantibody With Preeclampsia Among Postpartum Women, Anum S. Minhas, Arthur J. Vaught, Michael Schär, Alborz Soleimani-Fard, Neal Fedarko, Wendy Bennett, Maria Darla Esteban, Sammy Zakaria, Josef Coresh, Allison G. Hays

Student Publications

No abstract provided.

Beyond The Bite: Exploring Mental Health Of Dental Faculty In Pakistan– A Multi-Institutional Study, Kamran Ali, Daniel Zahra, Ulfat Bashir, Alaa Daud, Hina Zafar Raja, Rob Witton, Mahwish Raja

Peninsula Dental School

IntroductionMental health issues are being reported increasingly amongst healthcare staff and students globally. The aim of this study was to investigate the frequency of common mental health issues amongst dental faculty members at multiple institutions in Pakistan.MethodsFollowing approval from the institutional ethics review board, dental faculty members at 14 dental institutions were invited to participate in an online survey based on globally validated scales for mental health problems including the Patient Health Questionnaire (PHQ-9), and the Depression, Anxiety, and Stress Scale (DASS-21). Two open-ended questions were included in the survey to identify perceived factors contributing to poor mental health and …

In Re Gardner: Withdrawing Medical Care From Persistently Vegetative Patients, John K. Veroneau

Maine Law Review

As medical science and technology progress, the distinction between traditional notions of life and death becomes increasingly blurred. Persons in dire medical conditions, lacking all cognitive and sensory abilities, may now be kept "alive" for indefinite periods of time. In the seminal case of In re Quinlan, a court was first asked whether it was ever legally permissible to withhold or withdraw life-preserving care from a persistently vegetative person. Since In re Quinlan, the courts of many states, including Maine, have confronted this issue. In In re Gardner, the Maine Supreme Judicial Court, sitting as the Law Court, affirmed a …

Milton V. Cary Medical Center: A Viable Fetus Is Not A Person Under Maine's Wrongful Death Statute, Stan Piecuch

Maine Law Review

In Milton v. Cary Medical Center, a sharply divided Maine Supreme Judicial Court, sitting as the Law Court, refused to recognize a right of action for the wrongful death of a viable fetus. The court held that a viable fetus is not a person for purposes of applying Maine's wrongful death statute and that, consequently, the mother of a stillborn child could not maintain an action for the child's death. The court determined that the legislative history of the statute indicated that the Legislature did not intend the remedy to apply in the case of a child not born alive. …

The Future Of Sir, Dr.Luke Berryman, Peter Dong

Professional Learning Day

No abstract provided.

Innovation Hubs: Expanding Stem Access In Illinois, Nashwa Mekky, Will Perkins, Dawn Waller, Patrick Young, Janine Barajas, Charity Freeman M.Ed., Lindsey Herlehy, Joseph Mastrocola

Professional Learning Day

No abstract provided.

Ai Leadership In 9-12 Education: Research, Ethics, Pedagogy, And Entrepreneurship, Dr.Eric Rettberg, Dr.Ashwin Mohan, Tami Armstrong, Charity Freeman, Steve Goldblatt

Professional Learning Day

No abstract provided.

Road Signs Detection Using Ssd Mobilenetv2, Zahraa Salah Dhaif, Nidhal K. El Abbadi

Karbala International Journal of Modern Science

One of the most critical challenges for self-driving vehicles is accurately identifying traffic signs, which are essential for self-navigation and decision-making. Systems for the detection and recognition of road signs play a crucial role in this process by providing vital information for the vehicle's decision-making. This study proposes an approach for road sign identification and recognition utilising the TensorFlow Object Detection API and the SSD MobileNet V2 FPN Lite model.

In this proposal, we combine the efficiency and accuracy of SSD with the lightweight architecture of MobileNet to achieve excellent performance in object detection benchmarks while maintaining a small model …

Mitral Valve Prolapse With Syncope: Don’T Judge The Book By Its Cover! - Case Report, Ghadah A. Alarify, Lama A. Alrumaih, Sameer Qetab, Wael Alqarawi

Journal of the Saudi Heart Association

A 33-year-old female with recurrent syncope episodes showed normal ECG and Holter results, but had mitral valve prolapse (MVP) with moderate mitral regurgitation (MR) on an echocardiogram. Cardiovascular magnetic resonance (CMR) revealed mitral annulus disjunction (MAD) with fibrosis. She received an implantable loop recorder (ILR). Months later, she had a syncope correlating with self-terminating polymorphic VT (PMVT) preceded by narrow complex tachycardia, which was proven to be atrioventricular nodal reentrant tachycardia (AVNRT) in an electrophysiology study. Post-ablation, she had no recurrences of syncope. This case highlights the importance of ILR in avoiding unnecessary ICDs in MVP patients with syncope. .

Iridoid Glucosides Against Staphylococcus Aureus Infection And Inhibit Inflammation On Bovine Mammary Epithelial Cells, Yanfang Zhang, Ping Xu

The Thai Journal of Veterinary Medicine

Staphylococcus aureus can cause diseases in humans and livestock, destroy the body barrier, exacerbate inflammation, and seriously threaten human health and animal husbandry development. Iridoid glucosides isolated from Rehmannia glutinosa, is an important Chinese tradition medicine widely used in various diseases. The aim of this study was to investigate whether the iridoid glucosides was effective against S. aureus infection, and inhibits inflammation on bovine mammary epithelial cells. The antibacterial potential was determined using the in vitro broth microdilution assay against S. aureus. Then, the antibiofilm activity was tested by BCA protein assay, electric conductivity assay and scanning electron …

Molecular Detection And Characterization Of Histomonas Meleagridis In Fighting Cocks Thailand, Piyanan Taweethavonsawat, Mangsatabam Norjit Singh, Sawang Kesdangsakonwut, Wanarit Jitsamai, Chongtham Sonia, Cherdpong Phupolpan

The Thai Journal of Veterinary Medicine

Histomoniasis caused by the protozoa Histomonas meleagridis is a disease of gallinaceous birds which is of special importance to the poultry industry. The turkey is highly susceptible and results in high mortality. However, the disease is less severe in chickens but sometimes leads to mortality especially in those reared in the free-range system. During the present study, four dead fighting cocks were presented to the Veterinary Diagnostic Laboratory, Livestock Animal Hospital, Faculty of Veterinary Science, Chulalongkorn University for post-mortem examination. Based on history and pathological changes, it was preliminarily diagnosed as histomoniasis. The affected livers and caeca samples were collected …

October 2024 Academic Affairs Minutes, University Of Nebraska At Kearney Academic Affairs Committee

Academic Affairs Committee Minutes

No abstract provided.

The Chanticleer, 2024-10-17, Coastal Carolina University

The Chanticleer Student Newspaper

The editorially independent student produced weekly newspaper of Coastal Carolina University.

2024.10.17 - Academic/Student Affairs, Enrollment, And Technology Committee Meeting Minutes, Northeastern Illinois University Board Of Trustees

Board of Trustees - 2024

Meeting materials for the NEIU Academic/Student Affairs, Enrollment and Technology Committee

The Current - Volume 35 Issue 4, Nova Southeastern University

Student Newspapers

No abstract provided.

Dynamic Retrieval Augmented Generation Of Ontologies Using Artificial Intelligence (Dragon-Ai)., Sabrina Toro, Anna V Anagnostopoulos, Susan M. Bello, Kai Blumberg, Rhiannon Cameron, Leigh Carmody, Alexander D Diehl, Damion M Dooley, William D Duncan, Petra Fey, Pascale Gaudet, Nomi L Harris, Marcin P Joachimiak, Leila Kiani, Tiago Lubiana, Monica C Munoz-Torres, Shawn O'Neil, David Osumi-Sutherland, Aleix Puig-Barbe, Justin T Reese, Leonore Reiser, Sofia Mc Robb, Troy Ruemping, James Seager, Eric Sid, Ray Stefancsik, Magalie Weber, Valerie Wood, Melissa A Haendel, Christopher J Mungall

Faculty Research 2024

BACKGROUND: Ontologies are fundamental components of informatics infrastructure in domains such as biomedical, environmental, and food sciences, representing consensus knowledge in an accurate and computable form. However, their construction and maintenance demand substantial resources and necessitate substantial collaboration between domain experts, curators, and ontology experts. We present Dynamic Retrieval Augmented Generation of Ontologies using AI (DRAGON-AI), an ontology generation method employing Large Language Models (LLMs) and Retrieval Augmented Generation (RAG). DRAGON-AI can generate textual and logical ontology components, drawing from existing knowledge in multiple ontologies and unstructured text sources.

RESULTS: We assessed performance of DRAGON-AI on de novo term construction …

Learning Outcomes, Benefits, And Challenges Of International Research Experiences For Students (Ires): An Exploratory Study Of An Ires Program In China, Yousef Jalali, James Barilla, Kirsten Davis, Vinod Lohani, Rolf Müller

Journal of International Engineering Education

Despite the increasing number of international programs targeting students’ learning of research and intercultural skills, there has been limited holistic investigation of students’ experiences employing both qualitative and quantitative methods. In this study, we incorporated several measures to explore students’ experiences in an International Research Experiences for Students (IRES) program, which benefited from the existing partnership between Virginia Tech in the U.S. and Shandong University in China. We examined students’ intercultural competence and interdisciplinary research skills and explored students’ stories of their lived experiences across three cohorts, each with five students, who completed the IRES program. Both open-ended survey responses …

Global Horizons: Assessing The Impact Of Study Abroad Programs On Intercultural Competence Development Pre-College Technology Students, Aparajita Jaiswal, Muna Sapkota

Journal of International Engineering Education

Across fields, college and university graduates are increasingly expected to perform effectively in diverse, multi-cultural work environments. Given this reality, Higher Education Institutions (HEIs) are actively designing strategies to help students develop intercultural skills. Prior research has revealed that deliberately structured study abroad programs are an effective approach to nurturing intercultural competence among graduates. Consciously designed study abroad programs can provide students with opportunities to learn and reflect on their experiences. In this study, we aim to understand the impact of a study abroad program on pre-freshmen students enrolled in a College of Technology. Using a mixed-methods design, we examined …

Medical School Watercooler Newsletter - October 17, 2024, Lindsay Hughes

Watercooler Newsletter

This is the Thursday, October 17, 2024 edition of the Frederick P. Whiddon College of Medicine's newsletter -- Watercooler.

Contents include:

• Rx for Success pre-orientation course empowers future medical professionals
• USA Medical Alumni Association kicks off annual fund campaign
• Medical students, residents participate in American Academy of Pediatrics National Conference
• USA Health Game Day 2024 honors employees
• Whiddon COM alumnus chosen as White House Fellow
• Children's & Women's Hospital joins multicenter study on cardiac arrest care for pediatric patients 
• Mbaka studies new tool for weaning patients from ventilator

Biological Response Of Treatment With Saffron Petal Extract On Cytokine-Induced Oxidative Stress And Inflammation In The Caco-2/Human Leukemia Monocytic Co-Culture Model., Federica De Cecco, Sara Franceschelli, Valeria Panella, Maria Anna Maggi, Silvia Bisti, Arturo Bravo Nuevo, Damiano D'Ardes, Francesco Cipollone, Lorenza Speranza

PCOM Scholarly Works

The pathogenesis of Inflammatory Bowel Disease (IBD) involves complex mechanisms, including immune dysregulation, gut microbiota imbalances, oxidative stress, and defects in the gastrointestinal mucosal barrier. Current treatments for IBD often have significant limitations and adverse side effects, prompting a search for alternative therapeutic strategies. Natural products with anti-inflammatory and antioxidant properties have demonstrated potential for IBD management. There is increasing interest in exploring food industry waste as a source of bioactive molecules with healthcare applications. In this study, a co-culture system of Caco-2 cells and PMA-differentiated THP-1 macrophages was used to simulate the human intestinal microenvironment. Inflammation was induced using …

Spectator 2024-10-17, Editors Of The Spectator

The Spectator

No abstract provided.

Gc Minutes Oct 17, 2024, Graduate Council

Graduate Council Minutes

No abstract provided.

Targeted Therapy In Breast Cancer: Advantages And Advancements Of Antibody-Drug Conjugates, A Type Of Chemo-Biologic Hybrid Drugs, Attrayo Mukherjee, Debasish Bandyopadhyay

School of Integrative Biological & Chemical Sciences Faculty Publications

Cancer is a significant health challenge globally, with millions of people affected every year, resulting in high morbidity and mortality. Although other treatment options are available with limitations, chemotherapy, either standalone or combined with other therapeutic procedures, is the most commonly used practice of treating cancer. In chemotherapy, cancer cells/malignant tumors are targeted; however, due to less target specificity, along with malignant cells, normal cells are also affected, which leads to various off-target effects (side effects) that impact the patient quality of life. Out of all the different types of cancers, breast cancer is the most common type of cancer …