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Piezosurgery - Modern Dentistry's Innovative Tool - A Review Article, Amjed Kadhim Al-Naaly, Ahmed Fadhel Al-Quisi

Maaen Journal for Medical Sciences

Background: In implantology, piezosurgery is a novel and cutting-edge method of bone surgery. Various ultrasonic frequencies can be used for selective cutting, which preserves essential anatomical structures by only operating on solidified hard tissues. Piezoelectric osteotomy is a technique that can be used to precisely and safely prepare receptor sites for procedure implants, acquire bone grafts classified as autogenous (blocks and particles), perform osteotomies used for alveolar crest bone expansion, lift the maxillary sinus, and remove dental implants. Clinically and physiologically, the outcomes are outstanding, especially regarding osteocyte vitality.

Objectives: This review aims to highlight the advantages and …

Utilization Of Phytoplankton Distribution And Water Quality Criteria For The Environmental Assessment: A Case Study On Lake Manzala, Egypt, Mahmoud A. Abdelmoneim, Abdel Aziz M. Radwan, Tamer A. El-Betar

Blue Economy

Aim

Lake Manzala is a dynamic ecosystem, receiving enormous pollutants and wastewater that pose serious environmental threats and risks. Using integrated methods for environmental assessment in Lake Manzala, as an applied model, is what the current study aspires to achieve.

Methods

Sampling was carried out via 8 stations, covering the entire Lake during November 2022. Phytoplankton distribution and water quality index (WQI) were investigated.

Results and conclusions

A total of 60 phytoplankton taxa, belonging to five classes were obtained. Bacillariophyceae was the most productive (27 sp.) and predominated by Nitzschia. Cyanophyceae. Chlorophyceae, Dinophyceae and Euglenophyceae were detected and represented by …

The Fierce Green Fire: Vol. 15 Issue 2, Wofford College Environmental Studies Program

The Fierce Green Fire

No abstract provided.

2024-10-18 Minutes Of The Academic Senate, University Of Dayton. Academic Senate

Academic Senate Minutes

Approved minutes of a meeting of the Academic Senate of the University of Dayton.

Coastal Wetlands In The Anthropocene, John Day, Edward Anthony, Robert Costanza, Douglas Edmonds, Joel Gunn, Charles Hopkinson, Michael E. Mann, James Morris, Michael Osland, Tracy Quirk, Andre Rovai, John Rybczyk, Thomas Spencer, Jessica Stephens, Jaia Syvitski, Robert Twilley, Jenneke Visser, John R. White

Faculty Publications

We review the functioning and sustainability of coastal marshes and mangroves. Urbanized humans have a 7,000-year-old enduring relationship to coastal wetlands. Wetlands include marshes, salt flats, and saline and freshwater forests. Coastal wetlands occur in all climate zones but are most abundant in deltas. Mangroves are tropical, whereas marshes occur from tropical to boreal areas. Quantification of coastal wetland areas has advanced in recent years but is still insufficiently accurate. Climate change and sea-level rise are predicted to lead to significant wetland losses and other impacts on coastal wetlands and the humans associated with them. Landward migration and coastal retreat …

Examining The Relationship Between Employment And Health Status Among Adults With Autism Spectrum Disorder (Asd) In The United States, Winifred Beckles

Walden Dissertations and Doctoral Studies

Autism spectrum disorder (ASD), characterized by challenges in social communication and repetitive behaviors, is a developmental disability that impacts over five million adults in the United States. Despite the significant amount of research literature on the association between health and employment in the general population, there remains a gap in research on the relationship between health and employment in adults with autism. Utilizing the Social Ecological Model (SEM) framework, this study examined whether there is a relationship between employment, current living status, non-paid activities, United States Census regions, type of health insurance, and health status when controlling for age, race, …

Determination Of A New Spring-Flying Species Of The Pterourus Glaucus Complex (Papilionidae) In Southern New England, Harry Pavulaan

The Taxonomic Report of the International Lepidoptera Survey

The Pterourus glaucus complex in three southern New England states is analyzed for cryptic speciation. What was historically considered to be one species, P. glaucus (Linnaeus, 1758), was recently split to separate P. canadensis (Rothschild & Jordan, 1906) at species rank (Hagen et al., 1991). Additionally, P. appalachiensis Pavulaan & Wright, 2002, was described as an Appalachian Mountain endemic. The western member of the complex, P. rutulus (Lucas, 1852), has frequently been considered a subspecies of P. glaucus (Scott, 1986; Tyler, Brown & Wilson, 1994), as was P. alexiares (Höpffer, 1866) (Tyler, Brown & …

A Hematology-Based Clock Derived From The Study Of Longitudinal Aging In Mice To Estimate Biological Age., Jorge Martinez-Romero, Maria Emilia Fernandez, Michel Bernier, Nathan L Price, William Mueller, Julián Candia, Simonetta Camandola, Osorio Meirelles, Yi-Han Hu, Zhiguang Li, Nigus Asefa, Andrew Deighan, Camila Vieira Ligo Teixeira, Dushani L Palliyaguru, Carlos Serrano, Nicolas Escobar-Velasquez, Stephanie Dickinson, Eric J Shiroma, Luigi Ferrucci, Gary Churchill, David B Allison, Lenore J Launer, Rafael De Cabo, The Study Of Longitudinal Aging In Mice (Slam) Investigators

Faculty Research 2024

Biological clocks and other molecular biomarkers of aging are difficult to implement widely in a clinical setting. In this study, we used routinely collected hematological markers to develop an aging clock to predict blood age and determine whether the difference between predicted age and chronologic age (aging gap) is associated with advanced aging in mice. Data from 2,562 mice of both sexes and three strains were drawn from two longitudinal studies of aging. Eight hematological variables and two metabolic indices were collected longitudinally (12,010 observations). Blood age was predicted using a deep neural network. Blood age was significantly correlated with …

Pepperbox - October 18, 2024, Student Newspaper Of Arcata High School

The Pepperbox

Volume 97, Number 1

The Comment, October 18, 2024, Bridgewater State University

The Comment

No abstract provided.

A Novel Approach To Predicting Particle Deposition In A Human Lung Using A Lumped, Oscillatory Respiratory Model, Jordana E. O'Brien

Theses

Inhalation has become widely accepted as the optimal drug delivery mechanism for respiratory diseases, which often requires targeting a particular region of the lung. Mathematical models are key to under- standing the factors that influence drug transport and deposition in the lung. This study proposes a simple zero-dimensional typical path model that couples oscillatory breathing mechanics and particle deposition over multiple breathing cycles. Lung regions are lumped into compartments, and respiration is modeled using a circuit analog framework to capture airflows, lung pressures, and volumes in each lumped region. Particle transport and deposition are modeled by a mass-balance equation in …

Vulnerability, Resilience And Empowerment: The Tripartite Typology For Addressing Modern Slavery In Global Value Chains, Krzysztof Kubacki, Natalia Szablewska, Dariusz Siemieniako, Linda Brennan

Plymouth Business School

Purpose: Modern slavery in global value chains is an emerging topic of interest across various fields, including in international business, but is often fragmented in its approach. This study aims to provide a practical framework for studying relationships between participants in global value chains by exploring the nexus of three concepts – vulnerability, resilience and empowerment (VRE) – in the context of modern slavery. Design/methodology/approach: This article offers a deductive thematic analysis of 51 empirical and conceptual business research studies on modern slavery in global value chains published until mid-2021 according to the three categories of interest at the micro …

Evaluation Of Ki-67 Expression And Large Cell Content As Prognostic Markers In Mzl: A Multicenter Cohort Study, Natalie S. Grover, Kaitlin Annunzio, Marcus Watkins, Pallawi Torka, Reem Karmali, Andrea Anampa-Guzmán, Timothy S. Oh, Heather Reves, Montreh Tavakkoli, Emily Hansinger, Beth Christian, Colin Thomas, Stefan K. Barta, Praveen Ramakrishnan Geethakumari, Nancy L. Bartlett, Geoffrey Shouse, Adam J. Olszewski, Narendranath Epperla

Department of Medicine Faculty Papers

Marginal zone lymphoma (MZL) can have varied presentations and pathologic features, including high Ki-67 expression ( > 20%) as well as increased numbers of large B cells (LC). However, there are limited data available demonstrating the prognostic significance of these variables in patients with MZL. In this multi-institutional retrospective cohort study of patients with MZL treated at 10 centers, we evaluated the association between the presence of Ki-67 expression and increased LCs on survival and risk of histologic transformation (HT). A total of 785 patients were included (60% with extranodal MZL, 20% with nodal MZL, and 20% with splenic MZL). Among …

Antifibrotic Treatment Response Comparison Of Progressive Pulmonary Fibrosis And Idiopathic Pulmonary Fibrosis, Berna Akinci Özyürek, Kerem Ensari̇oglu, Tugce Sahi̇n Ozdemi̇rel, Esma Sevi̇l Akkurt, Ozlem Ozdag, Esma Zenbi̇lli̇

Turkish Journal of Medical Sciences

Background/Aim: Idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF) are two entities categorized fibrotic lung diseases. With a similar clinical presentation and treatment modalities in many cases, the line differentiating two diseases may not be evident. We aimed to evaluate the effectiveness of antifibrotic treatment and the course of fibrotic lung diseases. Material and Methods: The study included patients diagnosed with IPF and PPF who were given antifibrotic treatment and followed up for one year in our clinic. At one year, treatment response and radiological evaluation were investigated by high-resolution computed tomography. Results: Eighty-seven patients were included in the …

Internalizing Disorders Rather Than Adhd Are Risk Factors For Chronicity In Pediatric Migraine Patients, Nevra Öksüz, Gülen Güler Aksu, Asena Ayça Özdemi̇r, Aynur Özge

Turkish Journal of Medical Sciences

Background/aim: Migraine is a prevalent neurological disorder that can lead to disability in children and adolescents. It is frequently accompanied by psychiatric comorbidities, both internalizing and externalizing disorders. While the relationship between migraine and internalizing disorders has been studied, there is limited research on the link between migraine and attention deficit hyperactivity disorder (ADHD).Materials and methods: A total of 280 pediatric headache patients, 107 with externalizing (ADHD) and 173 with internalizing disorders (depression and/or anxiety), were included. The dataset was composed using the Turkish headache database, Mersin Branch. Pain characteristics, associated symptoms, and accompanying comorbidities were evaluated retrospectively.Results: Two hundred …

Open Surgical Approach To Fractures Of The Mandibular Condyle: Surgical Technique And Associated Complications, Cenk Demi̇rdover, Alper Geyi̇k

Turkish Journal of Medical Sciences

Background/aim: This study evaluates anatomical reduction and rigid internal fixation of mandibular condyle fractures using the preauricular retroparotid approach. It also, discusses advantages, deficiencies, and associated complications of the technique.Materials and methods: This retrospective study reviewed the medical records of a total of 52 mandibular condyle fractures, from 42 patients, who treated with open surgical approach using the preauricular retroparotid approach between January 2019 and 2024. Preoperative and postoperative assessments included measurements of mouth opening (maximum interincisal distance), vertical mandibular movement and facial paralysis. Moreover, the Vancouver Scar Scale (VSS) was used to evaluate scar quality at the surgical site. …

Production And Characterization Of Zn- And Cu-Doped Y2o3–Al2o3–Sio2 (Yas) Glass Microspheres, Fatma Unal, Batur Ercan

Turkish Journal of Medical Sciences

Background/aim: YAS glass microspheres are currently used in radioembolization treatment. However, abscess formation can occur following this treatment. The aim of this study is to endow YAS glass microspheres with antibacterial properties to address the abscesses that form in patients after radioembolization treatment.Materials and methods: In this study, undoped Y2O3–Al2O3–SiO2 (YAS) glass microspheres, as well as those doped with antibacterial agents zinc (Zn) and/or copper (Cu), were successfully fabricated using a sol-gel derived method.Results: After heat treatment, the microspheres exhibited an amorphous structure. Additionally, the incorporation of Zn and/or Cu dopants did not alter the patterns observed in the X-ray …

Phthalate Exposure Induces Cell Death And Ferroptosis In Neonatal Microglial Cells, Eli̇f Keleş, Lati̇fe Arzu Aral, Zübeyi̇r Elmazoğlu, Hasan Hüseyi̇n Kazan, Eli̇f Gülçi̇çek Abbasoğlu Topa, Mehmet Ali̇ Ergün, Hayrunni̇sa Bolay

Turkish Journal of Medical Sciences

Background/aim: Phthalates are the materials used for plasticizing polyvinyl chloride. Di-(2-Ethylhexyl) phthalate (DEHP) is one of the most frequently used phthalates in a wide range of applications, including medical equipment such as endotracheal and feeding tubes, intravenous catheters, central lines, extracorporeal membrane oxygenation sets, total parenteral nutrition bags, blood product sets, and intravenous pump lines, respiratory sets in neonatal intensive care units. Studies have shown that phthalates, including DEHP, can cross the placenta and blood-brain barrier, possibly leading to neurodevelopmental impairments in vitro and in vivo. However, the molecular mechanisms affected by phthalate exposure have not been explored in depth. …

Vitamin D3 Alleviates Intestinal Injury In Necrotizing Enterocolitis And Lipopolysaccharide-Induced Inflammatory Response In Dendritic Cells In Rats, Bo Ke, Chaoyu Li, Song Li, Jingjing Yan, Leke Sun

Turkish Journal of Medical Sciences

Background/aim: Necrotizing enterocolitis (NEC) is a serious condition that predominantly affects premature infants and involves an aberrant immune response and inflammatory cytokine release resulting in intestinal epithelial damage. The current study investigated the immunoregulatory effects of vitamin D3 on the maturation and activation of dendritic cells (DCs) and the antiinflammatory impact on the intestines in a neonatal rat model of NEC.Materials and methods: Inflammatory damage to intestinal tissue was assessed via morphological changes and apoptosis and DC expression of costimulatory molecules, inflammatory factors, and immunoregulatory factors by immunohistochemical staining, quantitative real-time PCR, and immunofluorescence. The fluorescein isothiocyanate-ovalbumin (FITC-OVA) uptake assay …

Management Of Acute Pain In Adults With Sickle Cell Disease: The Experience Of The Clinical Hematology Department Of The University Of Dakar, Ali̇oune Badara Diallo, Moussa Seck, Mohamed Keita, Sokhna Aissatou Touré, Elimane Seydi Bousso, Baron Ngasia, Blaise Felix Faye, Fatma Dieng, Sali̇ou Diop

Turkish Journal of Medical Sciences

Background/aim: The evolution of sickle cell disease (SCD) is marked by the occurrence of painful episodes linked to the obstruction of micro-vessels by sickle cells, known as vaso-occlusive crises (VOC). The aim of our work was to report the practical aspects of the management of acute pain in adults with SCD. Recommendations based on these practices are also provided.Materials and methods: We conducted a prospective, cross-sectional, descriptive and analytical study over a 4-month period of all sickle cell patients admitted to emergency departments for VOC. The parameters studied were sociodemographic, clinico-biological, therapeutic and evolutionary.Results: 118 cases of VOC were identified, …

Characterizing The Progression From Mild Cognitive Impairment To Dementia: A Network Analysis Of Longitudinal Clinical Visits, Muskan Garg, Sara Hejazi, Sunyang Fu, Maria Vassilaki, Ronald C Petersen, Jennifer St Sauver, Sunghwan Sohn

Faculty, Staff and Student Publications

Background: With the recent surge in the utilization of electronic health records for cognitive decline, the research community has turned its attention to conducting fine-grained analyses of dementia onset using advanced techniques. Previous works have mostly focused on machine learning-based prediction of dementia, lacking the analysis of dementia progression and its associations with risk factors over time. The black box nature of machine learning models has also raised concerns regarding their uncertainty and safety in decision making, particularly in sensitive domains like healthcare.

Objective: We aimed to characterize the progression of health conditions, such as chronic diseases and neuropsychiatric symptoms, …

Volume Cxliv, Number 4, October 18, 2024, Lawrence University

The Lawrentian

No abstract provided.

Discovery Of Genes That Positively Affect Biomass And Stress Associated Traits In Poplar, Tatyana Georgieva, Yordan Yordanov, Elena Yordanova, Md Rezaul Khan, Kaiwen Lyu, Victor Busov

Michigan Tech Publications

Woody biomass serves as a renewable resource for various industries, including pulp and paper production, construction, biofuels, and electricity generation. However, the molecular mechanisms behind biomass traits are poorly understood, which significantly curtails the speed and efficiency of their improvement. We used activation tagging to discover genes that can positively affect tree biomass-associated traits. We generated and screened under greenhouse conditions a population of 2,700 independent activation tagging lines. A total of 761 lines, which had significantly and positively affected at least one biomass-associated trait, were discovered. The tag was positioned in the genome for forty lines which were affected …

An Age-Structured Model For The Effects Of Temperature And Rainfall On The Transmission Dynamics Of Malaria, Alanus Mapunda, Eunice Mureithi, Nyimvua Shaban

Tanzania Journal of Science

This study has investigated the impact of temperature and rainfall on the transmission dynamics of malaria using an age-structured population model, with a class of pregnant women. The equilibrium solutions have been analyzed, and numerical simulations carried out. The results show that there are significantly high rates of malaria infections for the temperature and rainfall ranging between (23.53 0C − 39.80 0C) and (14.82 mm − 38.44 mm) respectively. The results have shown that, the most affected populations are children up to five years old and pregnant women, and that decreasing the rate of transplacental transmission increases the number of …

Loss Of Wwox Contributes To Cisplatin Resistance In Triple-Negative Breast Cancer Cells By Modulating Mir-182 And Mir-214, Bahadi̇r Batar, Eli̇f Serdal, Berna Erdal, Hasan Ogul

Turkish Journal of Medical Sciences

Arkaplan/Amaç: WW domain içeren oksidoredüktaz (Wwox) kaybı sıklıkla üçlü negatif meme kanserinde (TNBC) görülür. Wwox kaybı TNBC hastalarında sisplatin direncini artırır. Wwox kaybı, gelişmiş mutageneze katkıda bulunan bir DNA onarım yolunun seçimini etkilese de, dirençli kanser hücrelerindeki aşağı akış ekspresyonu değişiklikleri tam olarak araştırılmamıştır. Bu çalışma, Wwox eksikliği olan TNBC hücrelerinde sisplatin direncinin düzenlenmesinde mikroRNA'ların (miRNA'lar) potansiyel rolünü araştırmayı amaçlamıştır.Materyaller ve yöntemler: MDA-MB-231 hücrelerinde Wwox'u aşırı ifade etmek için geçici transfeksiyonlar gerçekleştirildi. Wwox'u aşırı ifade eden MDA-MB-231 hücreleri western blot ile belirlendi. miRNA'nın ekspresyon profili bir Real-Time PCR sistemi ile değerlendirildi.Sonuçlar: Wwox eksikliği ve yeterliliği olan MDA-MB-231 hücrelerinin miRNA ekspresyon …

Hydrodynamic Exposure – On The Quest To Deriving Quantitative Metrics For Mariculture Sites, Oliver Lojek, Nils Goseberg, Heidi Moe Føre, Tobias Dewhurst, Thea Bölker, Kevin Gerald Heasman, Bela H. Buck, David W. Fredriksson, Samuel Rickerich

Faculty Publications

This work attempts to define metrics for hydrodynamic exposure, using known oceanographic variables to provide a universal site assessment method for mariculture structures. Understanding environmental conditions driving open-ocean mariculture siting is crucial in establishing consistent ocean governance, minimizing adverse environmental impacts, and facilitating economically sustainable farm operations. To provide a metric of oceanic conditions and associated requirements for structural design and operation of aquaculture systems, six Exposure Indices (EI) are proposed that consider physical energy levels related to hydrodynamic forces at a site. Four of the proposed indices consider only environmental conditions, while the other two also consider the dimensions …

Health Risks Associated With Adopting New-Generation Disposable Products Among Young Adults Who Use E-Cigarettes, Shuyao Ran, James J Yang, Megan E Piper, Hsien-Chang Lin, Anne Buu

Faculty, Staff and Student Publications

New-generation disposable e-cigarettes have become increasingly popular among young adults in the USA since the FDA's partial flavor ban. This study aims to examine longitudinal changes in health risks among young adults who adopted these novel products, as well as the health effects of device types beyond the effects of other important e-cigarette characteristics. This study recruited e-cigarette users via voluntary response sampling from three college campuses in the USA to respond to four-wave online surveys conducted in four consecutive semesters. Among the participants who adopted disposables during the study, their health risks (dependence symptoms, respiratory symptoms, combustible tobacco use) …

Moving Beyond Wastewater: Perspectives On Environmental Surveillance Of Infectious Diseases For Public Health Action In Low-Resource Settings., Jeseth Delgado Vela, Sarah E. Philo, Joe Brown, Mami Taniuchi, Molly Cantrell, Alexandra Kossik, Maya Ramaswamy, Sitara Sr Ajjampur, Fatma Z. Guerfali, Rochelle H. Holm, John Scott Meschke, Maria Catherine B. Otero, Amy J. Pickering, Mahbubur Rahman, Alexander G. Shaw, Abhilasha Shrestha, Kwanrawee Sirikanchana, Vivi Maketa Tevuzula, Rolf U. Halden, Alexandria B. Boehm, Kyle Bibby

Faculty and Staff Scholarship

No abstract provided.

Post-Transcriptional Methylation Of Mitochondrial-Trna Differentially Contributes To Mitochondrial Pathology, Sunita Maharjan, Howard Gamper, Yuka Yamaki, Thomas W. Christian, Robert Y. Henley, Nan-Sheng Li, Takeo Suzuki, Tsutomu Suzuki, Joseph A. Piccirilli, Meni Wanunu, Erin L. Seifert, Douglas C. Wallace, Ya-Ming Hou

Department of Biochemistry and Molecular Biology Faculty Papers

Human mitochondrial tRNAs (mt-tRNAs), critical for mitochondrial biogenesis, are frequently associated with pathogenic mutations. These mt-tRNAs have unusual sequence motifs and require post-transcriptional modifications to stabilize their fragile structures. However, whether a modification that stabilizes a wild-type (WT) mt-tRNA would also stabilize its pathogenic variants is unknown. Here we show that the N¹-methylation of guanosine at position 9 (m¹G9) of mt-Leu(UAA), while stabilizing the WT tRNA, has a destabilizing effect on variants associated with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes). This differential effect is further demonstrated, as removal of the m¹G9 …

Association Between Systemic Zinc And Oxidative Stress Levels And Periodontal Inflamed Surface Area, Ayşegül Sari, Serdar Doğan, Luigi Nibali

Turkish Journal of Medical Sciences

Background/aim: Zinc is a structural component of some enzymes. The aim of this study was to evaluate the potential associations between serum zinc and oxidative stress levels and periodontal inflamed surface area (PISA).Materials and methods: This study included 90 patients divided into three groups: a periodontitis group (P; n = 30), a gingivitis group (G; n = 30), and a periodontal health group (PH; n = 30). Periodontal parameters were recorded and PISA values were calculated. Serum total antioxidant status (TAS), total oxidant status (TOS), and zinc levels were examined biochemically. Oxidative stress index (OSI) levels were calculated.Results: All clinical …