Digital Commons Network^™

Sex- And Gender-Specific Considerations In Mycotoxin Screening: Assessing Differential Exposure, Health Impacts, And Mitigation Strategies, Gayathree Thenuwara, Bilal Javed, Singh Baljit, Hugh J. Byrne, Furong Tian

Articles

Mycotoxins, toxic secondary metabolites produced by fungi, present significant health risks through contaminated food and feed. Despite broad documentation of their general impacts, emerging research highlights the requirement of addressing both sex- and gender-specific differences in the risk of exposure, susceptibility, and health outcomes in mycotoxin screening and mitigation strategies. Distinct biological (sex-based) and sociocultural (gender-based) factors can influence the risk of mycotoxin exposure and subsequent health impacts; women may for example exhibit specific exposures to certain mycotoxins due to physiological and hormonal differences, with increased risks during critical life stages such as pregnancy and lactation. Conversely, men may demonstrate …

Biosensor-Enhanced Organ-On-A-Chip Models For Investigating Glioblastoma Tumor Microenvironment Dynamics, Gayathree Thenuwara, Bilal Javed, Baljit Singh, Furong Tian

Articles

Glioblastoma, an aggressive primary brain tumor, poses a significant challenge owing to its dynamic and intricate tumor microenvironment. This review investigates the innovative integration of biosensor-enhanced organ-on-a-chip (OOC) models as a novel strategy for an in-depth exploration of glioblastoma tumor microenvironment dynamics. In recent years, the transformative approach of incorporating biosensors into OOC platforms has enabled real-time monitoring and analysis of cellular behaviors within a controlled microenvironment. Conventional in vitro and in vivo models exhibit inherent limitations in accurately replicating the complex nature of glioblastoma progression. This review addresses the existing research gap by pioneering the integration of biosensor-enhanced OOC …

Characterization Of Spent Grain From Irish Whiskey Distilleries For Biorefinery Feedstock Potential To Produce High-Value Chemicals And Biopolymers, Rasaq S. Abolore, Dileswar Pradhan, Swarna Jaiswal, Amit K. Jaiswal

Articles

Distiller's spent grain (DSG) is a byproduct generated in large quantities during the mashing process, particularly in the production of alcoholic beverages such as whiskey. This study aimed to characterize DSG from nine different distilleries as a potential biorefinery feedstock for the synthesis of high-value bioproducts. Key components, including protein (12.38–26.32%), cellulose (11.75–32.75%), hemicellulose (6.97–19.47%), lignin (8.44–15.71%), and total phenolics (1.42 to 3.97 mg GAE/g), were analyzed to evaluate their variability and suitability for industrial applications. The results reveal that DSG composition varies significantly across distilleries due to differences in processing techniques, even though the starting grain composition had minimal …

Tomelleri V. Sunfrog, Eastern District Of Michigan

Historical and Topical Legal Documents

No abstract provided.

Mata V. Meta Platforms, California Superior Court

Historical and Topical Legal Documents

No abstract provided.

Me-Em Enewsbrief, December 2023, Department Of Mechanical Engineering-Engineering Mechanics, Michigan Technological University

Department of Mechanical and Aerospace Engineering eNewsBrief

No abstract provided.

Sediment Carbon Storage In Subtidal Beds Of The Invasive Seagrass Halophila Stipulacea Along An Extreme Water Depth Gradient, St. Thomas, U.S. Virgin Islands, Demian A. Willette, Kelsey M. Vaughn, Allie Durdall, Marilyn Brandt, Sophia Costa, Kristin Wilson Grimes

Biology Faculty Works

Blue carbon ecosystems such as mangroves, salt marshes, and seagrass beds are found globally and are fundamental to fisheries production, storm surge protection, and carbon sequestration. The contribution of seagrass ecosystems to global carbon stocks is still not well understood, including in the United States Virgin Islands (USVI). No study has been published to-date assessing the sediment carbon density (SCD) in seagrass beds in the USVI. This study focused on the carbon storage ability of the invasive species, Halophila stipulacea, which is compact in size compared to common native seagrasses and has spread rapidly to become a dominant seagrass in …

A Case Report: Regenerative And Robotic Rehabilitation In A Patient With Chronic Hypoxic-Ischemic Encephalopathy, Chieh Chen, Sun-Hui Tseng

Rehabilitation Practice and Science

Hypoxic-ischemic encephalopathy (HIE) occurs when the brain is deprived of sufficient oxygen or blood flow, resulting in brain dysfunction. According to the relevant literature, no curative therapies are currently available for HIE-related lifelong disabilities. Regenerative rehabilitation employs regenerative technologies and cell therapy combined with conventional therapeutic exercises to restore normal function. This study used robotic-assisted gait training with the Lokomat and two infusions of human umbilical cord mesenchymal stem cells (hUC-MSCs) to treat an adolescent with chronic HIE. At the seven-month follow-up assessment, we determined that the patient’s motor function had improved based on the Gross Motor Function Measure-88 (GMFM-88) …

Early Season Biomass And Weather Enable Robust Cereal Rye Cover Crop Biomass Predictions, Alexandra M. Huddell, Brian Needleman, Eugene P. Law, Victoria J. Ackroyd, Muthukumar V. Bagavathiannan, Kevin Bradley, Adam S. Davis, Jeffrey A. Evans, Wesley Jay Everman, Michael Flessner, Nicholas Jordan, Lauren M. Schwartz-Lazaro, Ramon G. Leon, John L. Lindquist, Jason K. Norsworthy, Lovreet S. Shergill, Mark Vangessel, Steven B. Mirsky

Department of Agronomy and Horticulture: Faculty Publications

Farmers need accurate estimates of winter cover crop biomass to make informed decisions on termination timing or to estimate potential release of nitrogen from cover crop residues to subsequent cash crops. Utilizing data from an extensive experiment across 11 states from 2016 to 2020, this study explores the most reliable predictors for determining cereal rye cover crop biomass at the time of termination. Our findings demonstrate a strong relationship between early-season and late-season cover crop biomass. Employing a random forest model, we predicted late-season cereal rye biomass with a margin of error of approximately 1,000 kg ha⁻¹ based on …

The Development Of Internalized Sexism In Young Adult Women, Kylie Schwabe

Antioch University Dissertations & Theses

The present study utilized Interpretative Phenomenological Analysis in order to examine the lived experiences of young adult, cisgender women and the development of internalized sexism. Eight participants completed semi–structured interviews focused on their relationships with other women and subsequent views of womanhood. Themes found were (a) womanhood is taught by women throughout the lifespan, (b) women are sexually responsible for men, (c) women are emotional caregivers, (d) there are biological bases of womanhood, (e) women are expected to “do it all,” (f) expectations of women are fueled by media portrayal, (g) traditional femininity is seen as oppositional to the feminist …

Romantic Relationships And Adult Third Culture Kids, Samantha B. Hoffmann

Antioch University Dissertations & Theses

This study explored the lived experiences of romance and love among the Adult Third Culture Kids (ATCKs) population. A total sample of 10 participants was collected for the purpose of the study (five female and five male). Participants were of varying ethnicities, 25–46 years of age, met the study criteria for TCK identity, and reported at least one previous or current romantic relationship. Participants endorsed a history of a mobilized lifestyle and living in countries differing from their own passport country prior to the age of 18. Utilizing an Interpretive Phenomenological approach, participants were interviewed remotely and asked to describe …

User Acceptance Towards Virtual Reality For Basic Life Supports Teaching In A Multi Professional Education Context, Diantha Soemantri, Uti Nilam Sari, Aldy Heriwardito, Luthfi Saiful Arif

Health Professions Education

Purpose. To examine students’ acceptance of basic life support (BLS) virtual reality (VR). The study’s aim is based on the first level of Kirkpatrick’s evaluation model. Method. A cross-sectional study examined at Health Sciences Cluster (HSC) students’ acceptance of BLS VR used in a multi-professional course conducted in the HSC Universitas Indonesia, in 2023. A total of 759 first-year HSC students from five professions/schools (medicine, dentistry, nursing, pharmacy and public health) were recruited in this study. The exploratory factor analysis (EFA) with maximum likelihood and varimax rotation was used to assess the questionnaire’ construct validity. An open ended question was …

Addressing The Crisis In Meaning And Identity Through Covenant Relationship, Jenet Jacob Erickson

Religious Educator: Perspectives on the Restored Gospel

Our youth are experiencing a profound hunger for connection, evidenced by an epidemic of loneliness and increasing mental health challenges despite the seeming connectivity of a world swimming in social media. The deepest loneliness stems from disruption and disorder in family life, including ruptured or never formed family relationships. In answer to this relational fracturing, the gospel of Jesus Christ offers covenant belonging and connection. The revealed understanding of the nature of our covenant relationship with Jesus Christ and his work in enabling eternal bonds within the family and across the entire eternal family is at the heart of helping …

Blood Lead Level And School Violence Among Male Secondary School Students In A-Kut City Center/ Wasit Province, Isam Salim Ismaiel, Khalida Abdul-Sattar, Hasan Alwan Baiee

Hilla University College Journal For Medical Science

Background: Toxic level of blood lead among schoolchildren was associated with violent behavior and may lead to delinquencies and truancy as well as low social skills and poor school performance.

Objective: to assess blood lead level among sample of students in secondary schools in Kut City and determining its relation to violent behavior.

Methods: A cross-sectional study was carried out targeting students in three secondary schools in Kut City/Iraq. A convenience sample of 54 students were selected where; (27 violent students and 27 non-violent students) according to certain reference criteria.

Results: This study shows that 74% of our students had …

Quantitative Determination Of Sulfamethoxazole Using Various Spectroscopic Methods, Abdulla M. Sulaiman, Aws M. Nejres, Ali M. Hussain

Hilla University College Journal For Medical Science

Sulfamethoxazole is one of the important pharmaceutical preparations for which researchers have been trying to find sensitive and applicable spectroscopic methods for its estimation. The estimation methods were divided into five types: the standard method, which relied on the use of the protocol followed in the US pharmacopeia (USP), in addition to Titrimetic methods, spectroscopic methods, and voltammetry methods, the last of which used high-performance chromatography (HPLC) technology. The aim of this study is The process of counting the various spectroscopic methods used in estimating the pharmaceutical preparation sulfamethoxazole for the purpose of facilitating the research process for researchers.

Correlation Between Biofilm Formation And Antibiotic Resistance In Pseudomonas Aeruginosa Isolated From Various Clinical Specimens, Ali Kareem Ali, Lamees A. Abdul-Lateef

Hilla University College Journal For Medical Science

Background: Pseudomonas aeruginosa, is a Gram-negative nosocomial pathogen implicated in various human infections, primarily associated with healthcare services. Biofilms are known for their resistance to antimicrobial agents.

Objectives: The study aims to investigate the correlation between biofilm formation and antibiotic resistance in isolates.

Materials and Methods: The samples were collected from (110) patients admitted to two main hospitals in Hilla city: Al-Hilla General Teaching Hospital, and Mergan Teaching Hospital. The specimens were collected from various clinical sites such as wounds, ears, and urine.

Results: Out of (70) positive cultures cultured on Cerimide agar medium, only 15 (13.6%) specimens showed …

Analyzing The Possible Hepatic Protection Of Ursodeoxycholic Acid In Rat Models Of Carbon Tetrachloride-Induced Hepatotoxicity, Ayala Ya Seen Ali Bey, Maj Id Radium Barabbas, Ahmed Raj

Hilla University College Journal For Medical Science

Background: The liver is essential for the detoxification of toxic substances as well as for metabolism, storage, and secretion. The liver is the primary organ for the metabolism of proteins, lipids, and carbohydrates. Exposure to certain xenobiotics can cause oxidative stress, which can impair liver function.

Objectives: The current study aimed to evaluate the possible protective effect of ursodeoxycholic acid against the hepatotoxicity induced by carbon tetrachloride administration.

Materials and Methods: Thirty adult male albino rats weighing between 250 and 300 g and aged between 10 and 12 weeks were included in the study. Three groups were included; group …

Impact Of Physical Activity And Body Size On Serum Level Of Anti-Müllerian Hormone In Women In Babylon Province, Murtadha D. Mohsin, Ban J. Edan

Hilla University College Journal For Medical Science

Background: Anti-Müllerian hormone (AMH) is a glycoprotein produced by granulosa cells and has gained recognition as the most dependable serum biomarker for assessing ovarian reserve. AMH levels serve as an indicator of the quantity of primordial follicles and their likely response to external gonadotropins. Obesity may impact female fertility through direct harm to oocyte health and differentiation or by indirectly interfering with the pituitary-hypothalamic axis, leading to dysfunctional oogenesis.

Objectives: This study aims to evaluate the role of physical activity and body size on serum AMH levels in women.

Patients and Methods: A cross-sectional study was carried out on …

Potential Anti-Parkinsonian Activity Of Gastrodia Elata: The Principle Of Antioxidant Qualities In A Rat Model, Marwa S. Mahdy, Reyadh H. Al-Mosawi, Samir S. Hammoud

Hilla University College Journal For Medical Science

Background: Parkinson’s disease is a progressive, incurable, and the second most common neurological disorder resulting in the localized destruction of dopaminergic neurons in the pars compacta (PC) of the midbrain.

Objectives: Our study aimed to examine the antioxidant effect of Gastrodia elata on brain tissues of PD animal models depending on results obtained from previous investigations.

Materials and Methods: 40 Wistar adult male rats weighing 200-300mg were placed into 5 separate groups at random, with 8 rats in each group. The course of the study was a 21-day behavioral test carried out on day 21 using an open-field device. Decapitation …

Detection Of Newly Identified Phylogenetic Lineages In Uropathogenic Escherichia Coli Isolates In Iraq, Hiba J. Hamza, Huda H. Al-Hasnawy, Mohammed R. Judi, Hider M.H. Al-Shirifi

Hilla University College Journal For Medical Science

Background: Escherichia coli (E. coli) strains have been classified into eight distinct phylogenetic clusters as per a novel quadruplex PCR method. However, the exact phylogenetic relationship among these bacterial lineages is still uncertain. Objectives: The current study employed the Clermont phylotyping method to enhance the understanding of phylogenetic clusters of E. coli and evaluate antibiotic resistance in uropathogenic E. coli (UPEC) strains in Iraq. Materials and Methods: A total of forty-two UPEC isolates were evaluated for antibiotic susceptibility using a disk diffusion test, while the innovative Clermont phylotyping method was employed for the phylogenetic classification of the isolates. …

Influence Of Orthodontic Appliances On Oral Candida Albicans And Molecular Study Of Their Virulence Factors, Nebras Dawood Al-Jubouri, Nebrass Nasir-Alla Al-Dapagh, Wisam Wahab Sahib Alhamadi

Hilla University College Journal For Medical Science

Background: Candida albicans is commonly found in the oral cavities of individuals with denture stomatitis, especially in middle-aged and elderly adults who use dentures and orthodontic appliances. Objectives: This study aims to investigate the influence of orthodontic appliances on oral Candida albicans and demonstrate the isolation and identification of C. albicans from orthodontic patients. Materials ans Methods: Eighty swab samples were collected for culture preparation. The swabs were cultured on various culture media (such as Influence of Orthodontic Appliances on Oral Candida albicans and Molecular Study of their virulence factors, SDA, and Chrom agar) and the culture …

Molecular Analysis Of Fimh Gene In Biofilm-Producing And Multidrug Resistant Klebsiella Pneumoniae, Afrah Mehdi Alwan, Hanaa Naji Abdallah, Alaa Salim Hamzah

Hilla University College Journal For Medical Science

Background: Klebsiella pneumoniae is a significant gram-negative, opportunistic bacterium. Among the many infectious disorders it can cause are infections of the bladder, bacteremia, pneumonia, and hepatic abscesses. Biofilms slow down the rate of bacterial growth, prevent antibiotics from penetrating the body, encourage the creation of persister cells, and promote genetic exchange. Thus, biofilms can lead to an outbreak of superbug infections. Objectives: This study aimed to molecularly analyze the FimH gene in biofilm-producing and multidrug-resistant K. pneumoniae. Materials and Methods: 250 clinical samples were collected from several hospitals in Baghdad and from different clinical sources. Laboratory diagnosis was based …

Exploring The Role Of Nanoparticles In Combating Microbial Infections: A Mini Review, Khaldoon Jasim Mohammed, Abdulhakeem Dahham Hussein, Sundus Jassim Muhammad

Hilla University College Journal For Medical Science

Background: Drug-resistant organisms are on the rise globally, and therefore studies for new forms of antimicrobial agents. Among them, nanoparticles find much utility in drug delivery and possess effectiveness against antibiotic-resistant strains. Such an approach is a successful one for public health since it has relative advantages in eradicating microbial infections.

Objective: The aim of this mini-review is to discuss the role of nanoparticles and their functions on microbial infections, especially regarding their antimicrobial activity.

Method: This review involves the conduct of a systematic review of the literature through publications in different databases like PubMed, Scopus, and Web of Sciences, …

Biomarkers And The Identification Of Kidney Damage In Patients With Diabetes Mellitus, Hanan Hamid Ramadhan, Rasha Naseer Mohammed

Hilla University College Journal For Medical Science

The condition of diabetic renal disease is the most prevalent manifestation of chronic kidney disease and renal failure worldwide. It acts as the major diabetes complication and is characterized by the excretion of abnormal urinary albumin, impairment of glomerular filtration rate (GFR), and diabetic glomerular renal lesions. It is also associated with microvascular complications in diabetes mellitus.

The exact pathogenesis is complicated and unexplained. The pathogenesis pathways initiated and sustained in the kidney by increased glucose levels. They are enhanced by numerous different factors that involve several metabolic variables (excess of carbonyl, fatty acids, and oxidative stress) and hemodynamic variables …

Anti-Cancer Efficacy Of Silver Oxide Nanoparticles Synthesized Using Terephthalic Acid: A Comprehensive Study, Mohammed Talib Kamil Al-Alawi

Hilla University College Journal For Medical Science

Silver oxide nanoparticles (Ag2O NPs) synthesized using terephthalic acid have demonstrated significant potential as anti-cancer agents. This study aimed to synthesize these nanoparticles using an eco-friendly chemical reduction method and evaluate their anti-cancer efficacy against HepG2 liver cancer cells. The nanoparticles were characterized by Dynamic Light Scattering (DLS), Field Emission Scanning Electron Microscopy (FESEM), X-ray Diffraction (XRD), and Fourier-Transform Infrared Spectroscopy (FTIR). The characterization confirmed their spherical morphology, uniform size distribution, and well-defined crystalline structure, with an average particle diameter of approximately 75 nm. The anti-cancer potential of the synthesized nanoparticles was assessed through in vitro cytotoxicity and apoptosis assays. …

Assessment Of Response Of Enteropathic Spondyloarthritis To Different Types Of Biological Therapy; An Egyptian Single Center Study, Fatma Abozeid, Marwa Besar

Mansoura Medical Journal

Introduction: Arthropathy is one of the most prevalent extraintestinal symptoms of inflammatory bowel disease (IBD). It may be either peripheral or axial spondyloarthropathy. Biological treatment as anti-tumor necrosis factor alpha (TNF𝛼) or anti-interleukin 12/23 (anti IL 12/23) have shown efficacy in controlling gut inflammation and reducing joint manifestation. Our aim of the study was to assess the different aspects of response (laboratory , endoscopically and radiologically) of axial arthropathy associated with IBD patients after receiving biological drugs including: anti TNF (infliximab and adalimumab)& anti IL 12/23 (ustekinumab)

Patients & methods:A single center observational study was conducted through one …

Urinary Vitamin D Binding Protein Level In Egyptian Systemic Lupus Erythematosus Patients: A Potential Biomarker For Lupus Nephritis And Its Association With Renal Activity, Elshahat A. Yousef, Eman Nagy, Omnia M. El Sayed Mohamed, Mohamed S. Elghonimy, Marwa Saleh

Mansoura Medical Journal

Background : Systemic Lupus Erythematosus (SLE) is an autoimmune inflammatory disease affecting various organs, notably the kidneys, leading to lupus Nephritis (LN) in approximately half of patients. Early and accurate diagnosis of lupus nephritis (LN) and initiation of therapy are crucial steps in halting disease progression. Despite its value as a gold standard for diagnosing, classifying, and guiding treatment for LN patients, renal biopsy is expensive, carries risks, and cannot expect the response to immunosuppressive therapy. Methods : The study included 80 SLE patients; 60 patients were biopsy-proven LN (30 patients with active LN, and 30 patients with LN in …

Training The Concept Of Innovate In Dolphins (Tursiops Truncatus) Is Both Creative And Cognitively Stimulating, Deirdre Yeater, Kathleen M. Dudzinski, Dawn Melzer, Andrew R. Magee, Michaela Robinett, Gonzalo Guerra, Kimberly Salazar, Terri Bolton, Heather Manitzas Hill

Psychology Faculty Publications

Creative or novel behaviors in bottlenose dolphins (Tursiops truncatus) can be indicators of flexible thinking and problem solving. Over 50 years ago, two rough-tooth dolphins demonstrated creative novel behaviors acquired through reinforcement training in human care. Since this novel training, a variety of species have been trained to respond to this conceptual cue. The current study assessed the creativity of 12 bottlenose dolphins (5 females, 7 males) housed at the Roatan Institute for Marine Sciences (RIMS) in Roatan, Honduras. Individual differences were found across four constructs measured for creativity: fluency, flexibility, elaboration, and originality. Variability in performance occurred across test …

Sars-Cov-2 Infection History Is Positively Correlated With Frequency Of Psychotic Symptoms In Schizophrenia, Jackson D. Beecher

Honors Undergraduate Theses

Previous work in human and animal studies has implicated aberrant insular cortex (IC) activity in the pathophysiology of hallucinations. Of note, the IC overlaps with the olfactory cortex (OC), a region of the brain that receives extensive projections from sensory neurons of the olfactory epithelium. SARS-CoV-2 (COVID-19) is a highly infectious coronavirus with a demonstrated ability to cause anosmia; the virus does this by colocalizing with and damaging support cells in the olfactory epithelium, ultimately leading to alterations in olfactory receptor cell signaling to the OC. Given the overlap between OC and IC, we asked the question of whether COVID-19 …

Elements Of The Criminal Mind, Kelsie A. Esposito Ms.

Honors Undergraduate Theses

Studying human behavior and societal dynamics has captivated scholars across time. From ancient philosophers like Plato to contemporary researchers, the quest to comprehend our distinctiveness and the mechanisms that enable harmonious coexistence remains paramount. This thesis examines the enigmatic realm of the “criminal class,” looking at their identity and actions and the cognitive processes underpinning their behavior. Focusing on violent criminal offenders, this thesis seeks to provide greater meaning and understanding of the criminal mind.