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Bridging The Gap: Expanding Medical “Aid” In Dying For Als Patients, Morgan Schultz

Student Works

No abstract provided.

Graduate Program Survey Report 2023-2024, University Of Northern Iowa. Office Of Institutional Effectiveness & Planning.

Institutional Effectiveness & Planning Documents

Contents:

Graduate College Staff --- 01
Graduate Degrees Awarded Summer 2023 - Fall 2024 --- 02
Survey Methodology --- 04
Survey Highlights --- 05
Respondent Demographics --- 06
Principal Activities After Graduation --- 07
Activities Participated in at UNI --- 08
Comparison Between 2022-2023 & 2023-2024 --- 09
Reasons For Attending UNI --- 10
Academic Experience --- 11
Comparison of Academic Experience From 2021 - 2024 --- 13
Financing Graduate Education --- 15

Dna Origami-Assisted Regioselective Organization Of Anisotropic Gold Nanotriangle Clusters, Wenyan Liu, Prashant Gupta, Yuwei Zhang, Krishna Thapa, Srikanth Singamaneni, Risheng Wang

Chemistry Faculty Research & Creative Works

The manipulation of anisotropic nanoparticles, such as gold nanorods and nano prisms, has attracted great attention in nanotechnology due to their sensitive geometry-dependent properties. However. traditional synthesis and assembly methods for these particles face challenges in size uniformity and higher-order structuring. To address these limitations, this study presents a strategy using DNA origami triangles, not just as templates, but as encapsulating agents for gold nanotriangles (AuNTs). This method enables the construction of diverse nanoparticle clusters with precisely controlled distance and orientation. The formed clusters exhibit unique optical characteristics, demonstrated by UV-visible spectroscopy and supported by finite-difference time domain (FDTD) simulations. …

2024 Faculty Summer Seminar - Gracious Catastrophes: Contemporary Representations Of Mystery And Mercy In The Catholic Literary Imagination, Center For Catholic Studies, Seton Hall University

Center for Catholic Studies Faculty Seminars and Core Curriculum Seminars

About the 2024 Faculty Seminar & the Facilitator – p.6

Josephine De Vito – p.8 The Images of Motherhood as Reflective in Catholic Writings and Art

Matthew Higgins – p.12 Love of Things Invisible: A Theological Look at the Catholic Imagination

Mary Grace Mangano – p.18 The Catastrophe of Faith: A Close Reading of “The Expert on God” by John L’Heureux

Elizabeth Brewer Redwine – p. 22 “Mad Ireland Hurt You into Poetry: Gerard Manley Hopkins in Dublin

Judith Stark – p. 27 The Catholic Literary Tradition and Climate Changes

Gloria Thurmond – p.33 The Pre-Christian Celtic Roots of the …

Multifaceted Challenges And Opportunities: Concurrent Mixed Methods Research To Investigate Chinese Exchange Students' Experiences In The Us Transnational Online Learning Ecology, Xinyue Ren, Yi Zhou

STEMPS Faculty Publications

Transnational online education has become an emerging trend in promoting academic collaboration and exchange in higher education during and after the pandemic. Guided by the learning ecology framework, we conducted concurrent mixed methods research by distributing an online survey to Chinese students (N=51) to collect quantitative and qualitative data. This helped us deeply understand their experiences and perceptions of a cross-cultural online learning environment in the United States. We applied multiple regression and thematic analysis to analyze the data. The merging of both types of data analysis indicated the confirmation of the importance of discipline-based English learning environments, the transformation …

Effect Of Δnp63Β On Cell Cycle And Apoptosis In T98g Cells, Buse Turegun Atasoy, Fi̇kret Sahin

Turkish Journal of Medical Sciences

Background/aim: The p53 protein, a crucial tumor suppressor, governs cell cycle regulation and apoptosis. Similarly, p63, a member of the p53 family, exhibits traits of both tumor suppression and oncogenic behavior through its isoforms. However, the functional impact of ΔNp63β, an isoform of the p63 protein, on human glioma cancer cells like T98G cells remains poorly understood, representing the novelty of this study in the current literature.Materials, methods: Employing the pRetroX-Tet-On vector system, we investigated ΔNp63β's apoptotic effects on T98G cell lines and assessed its influence on the cell cycle. Initially, we established a rtTA-expressing vector, a component of the …

Investigating The Biomarker Potential And Molecular Targets Of Tigd1 In Lung Cancer Using Bioinformatics, Merve Gulsen Bal Albayrak, Tuğcan Korak, Murat Kasap, Gurler Akpinar

Turkish Journal of Medical Sciences

Background/aimLung cancer, a predominant contributor to cancer mortality, is characterized by diverse etiological factors, including tobacco smoking and genetic susceptibilities. Despite advancements, particularly in non-small cell carcinoma (NSCC), therapeutic options for squamous cell carcinoma (LUSC) are limited. Transposable elements (TE) and their regulatory proteins, such as Transposable element derived (TIGD) family proteins, have been implicated in cancer development. TIGD1, upregulated in various cancers, including LUSC, lacks a defined function. This study aimed to elucidate the biological functions, associated pathways, and interacting proteins of TIGD1.Materials and methodsThe GSE229260 microarray dataset were investigated using GEO2R tool to identify the differentially expressed genes …

Approaching A Nationwide Registry: Analyzing Big Data In Patients With Heart Failure, Tuğçe Çöllüoğlu, Anil Şahi̇n, Ahmet Çeli̇k, Emi̇ne Arzu Kanik

Turkish Journal of Medical Sciences

Background/aim:Randomized controlled trials usually lack generabilizity to real-world context.Real-world data, enabled by the use of big data analysis, serve as a connection between the results of trials and the implementation of findings in clinical practice.Nevertheless, using big data in the healthcare has difficulties such as ensuring data quality and consistency.This article aimed to examine the challenges in accessing and utilizing healthcare big data for heart failure (HF) research, drawing from experiences in creating a nationwide HF registry in Turkiye.Materials and methods:We established a team including cardiologists, HF specialists, biostatistics experts, and data analysts. We searched certain key words related to …

Gendered Orientalism And The Agency Of Syrian, Muslim Women Refugees, Karen Culcasi

Faculty & Staff Scholarship

Orientalist discourses have long recirculated the idea that Muslim women are oppressed victims of Islam; an idea that has denigrated Muslims and positioned white, Christians as superior. For Muslim women refugees specifically, the gendered orientalist discourse of victimization has reappeared on both sides of the debate on Syrian refugee resettlement in the United States (U.S.) (and other Western states). Within anti-resettlement circles, the narrative of Muslim women as oppressed victims has been leveraged as a reason to stop Syrian refugee resettlement; based on a rationale that their lifestyles and values are incompatible with liberal, Western societies. Pro-resettlement circles, on the …

Evaluation Of The Aquaporin Molecules Characterization In The Sperm Cells Of Men From Different Aged, Fikret Gevrek, Osman Serden Gencel, Selim Görgün, Mikail Kara, Muzaffer Katar

Turkish Journal of Medical Sciences

Male infertility rises for many reasons, along with age; therefore, we aimed to research the characterization of aquaporin-3, 7, and 8 in human sperm belonging to different age groups. Material and methods: This study was conducted on sperm samples of men aged over 18 years. A total of 60 men were included in the study and divided into three age groups: group 1, age 18–25 years (n = 20); group 2, age 26–35 years (n = 20); and group 3, age ≥35 years (n = 20). Sperm ejaculates obtained from each participant were used for spermiogram tests, Kruger strict morphology …

Risk Factors Of Congenital Nomalies Of The Kidney And Urinary Tract (Cakut): Exposureto Mobile Phones During Pregnancy, Kübra Çeleğen, Esra Özgül, Zeynep Yeşi̇ldağ, Erdem Yusuf Çamirci, Mehmet Çeleğen, Ayşegül Bükülmez

Turkish Journal of Medical Sciences

Congenital anomalies of the kidney and urinary tract(CAKUT) are the leading causes of childhood chronic kidney disease (CKD). The etiology of most of the cases is thought to be multifactorial. In this study, risk factors for CAKUT and the effect of mobile phone-related electromagnetic field (EMF) exposure during pregnancy were investigated.Materials and methods: Fifty-seven cases and 57 healthy controls under 2 years of age were included and their mothers were subjected to a questionnaire. Groups were compared for parents’ demographics, pregestational (chronic disease, body mass index, use of the folic acid supplements) and antenatal variables (gestational disease, weight gain during …

Evaluation Of Bone Health In Terms Of Osteoporosis In Adult Patients With Neuromuscular Disease, Özgür Zeliha Karaahmet, Eda Gürçay, Yasemin Tombak Yildizkan, Damla Cankurtaran, Zeynep Tuba Bahti̇yarca, Ebru Umay

Turkish Journal of Medical Sciences

There are no current guidelines to help clinicians decide whether patients with adult neuromuscular disease (NMD) should be screened or treated for osteoporosis (OP). This study was undertaken to investigate the presence of OP in patients with various types of NMD and to examine the relationship between OP evaluation parameters and functional status, daily living activities, balance, and ambulation levels.Materials and methods: This cross-sectional study included 45 patients with NMDs. The patients were divided into 3 groups, depending on the affected component of the motor unit (neuronopathy group, neuropathy group, and myopathy group). The laboratory and demographic data were recorded …

The Private Law Of Self-Help, João Marinotti

Articles by Maurer Faculty

Individuals regularly take steps to protect themselves, their property, and their broader legal interests. They carry pepper spray, have guard dogs, and install fences. Such measures are colloquially deemed methods of self-help. Yet, despite its ubiquity, self-help as a legal concept has been chronically understudied. Consequently, American private law is missing a doctrinally coherent and prescriptively useful framework for self-help. As a matter of legal theory, this conceptual void is problematic in and of itself; the doctrinal incoherence stemming from this analytical gap decreases the law’s stability and undermines its predictability.

But the concern is not merely theoretical. The magnitude …

Mechanistic Insights Into Direct Interactions That Mediate The Activity Of Dot1l Complex In Mll-Rearranged Leukemia, Ali Cihan

Student Theses and Dissertations

Acute leukemia can arise from the translocation-mediated fusion of the N terminus of the Mixed Lineage Leukemia (MLL) protein to various partner proteins. Although more than 60 different translocation-based fusion proteins have been identified, fusion partners such as AF9, AF10, and ENL constitute the majority of the MLL-rearranged leukemia cases; additionally, these fusion partners are also a part of the DOT1L (disruptor of telomeric silencing 1-like) complex. Aberrant histone H3 Lysine 79 (H3K79) methylation catalyzed by DOT1L was shown to be crucial for the maintenance of MLL-rearranged leukemia. DOT1L is the only known H3K79 methyltransferase, and further, a DOT1L inhibitor …

Rna Therapeutics For Fibrolamellar Hepatocellular Carcinoma, Christoph Neumayer

Student Theses and Dissertations

Fibrolamellar hepatocellular carcinoma (FLC) is a rare liver cancer characterized by a recurrent fusion of the heat shock protein DNAJB1 and the catalytic subunit of protein kinase A (PRKACA). Due to limited efficacy of conventional treatments such as chemotherapy and radiation my work explored new therapeutic options. As DNAJB1::PRKACA is known to initiate tumorigenesis, I reasoned that it would be an ideal target for a therapeutic. However, it was not known if FLC tumors are still dependent on DNAJB1::PRKACA or if cells achieved independence of the initial oncogene. To test if FLC is dependent on the oncokinase I screened short …

Updating Cost Allocation And Revenue Attribution, Isaiah C. Mwamba, Deepak Benny, Ajuna P. John, David O. Holguin Mejia, Dongyoon Song, Jelin Sabu, Jiqian Dong, Mohammadhosein Pourgholamali, Sashank Modali, Richard O. Ajagu, Bismark R. Agbelie, Matthew Volovski, Konstantina Gritzka, Kumares C. Sinha, Samuel Labi

JTRP Technical Reports

This report presents a synopsis of the results from the 2024 study commissioned by the Indiana Department of Transportation (INDOT) in fall 2023 at the request of the Indiana General Assembly.

Expenditures: Lighter vehicle classes saw their share of cost responsibility decline between 2015 and 2024, while the heavier vehicle classes saw their responsibilities increase within this period. This change is explained by a diametric shift in expenditure type patterns between the two eras from construction-dominant to maintenance-dominant expenditures. In this context, it is worth noting that these expenditure types have different ratios of attributable costs to common costs.

Revenues: …

Full-Scale Dynamic Wireless Power Transfer And Pilot Project Implementation, Oscar Moncada, Zainab Imran, Connor Vickers, Konstantina Gkritza, Steven Pekarek, Dionysios Aliprantis, Aaron Brovont, Behnam Jahangiri, John E. Haddock

JTRP Technical Reports

Considering the challenges hindering the widespread adoption of electric vehicles (EVs) and heavy-duty electric vehicles(HDEVs), the integration of dynamic wireless power transfer (DWPT) technology into roadways has gained interest. By embedding DWPT components into pavement, electrical power can be delivered to an EV or HDEV as they are in motion. Yet, large-scale implementation depends on further in-depth research, both to explore optimal construction methods and to understand the impact of embedment on the pavement’s resultant behavior. The objective of this project was trifold: (1) design and evaluate a transmitter-receiver topology for DWPT, (2) enhance the understanding of the interaction between …

Indot Project Change Orders: Root Causes And Recommendations, Suyash Padhye, Aishwarya Sharma, Hesam Arefkhani, Deepak Benny, Konstantina Gkritza, Samuel Labi, Makarand Hastak

JTRP Technical Reports

This study analyzed the historical trends in change orders (COs) associated with the Indiana Department of Transportation (INDOT) highway contracts. It also investigated correlations between COs and base factors (district, project type, contract type, award amount, geographical area (rural vs. urban)), and sought to understand the effect of the root causes but not to predict CO based on root causes. Unlike the base factors, the root causes are unknown prior to construction. The study developed models that forecasted CO characteristics—CO likelihood, CO frequency (count), and CO severity (magnitude) and CO impacts (cost overrun and schedule delay). To address these research …

Urban Nature Indexes Tool Offers Comprehensive And Flexible Approach To Monitoring Urban Ecological Performance, Jennifer Rae Pierce, Laura Costadone, Lelani Mannetti, Joeri Morpurgo, Charlyn Elaine Green, Michael D. Halder, Pablo Arturo Lopez Guijosa, Abner L. Bogan, Russell Galt, Jonathan Hughes

ODU Articles

We present the Urban Nature Indexes (UNI), a comprehensive tool that measures urban ecological performance under one standard framework linked to global commitments. The UNI was developed by interdisciplinary experts and evaluated by practitioners from diverse cities to capture each city’s ecological footprint from local to global scale. The UNI comprises six themes (consumption drivers, human pressures, habitat status, species status, nature’s contributions to people, and governance responses) that encompass measurable impacts on climate change, biodiversity loss, ecosystem services, pollution, consumption, water management, and equity within one comprehensive system. Cities then adapt the UNI to their context and capacity by …

Is Gut Microbiota Of Patients With Als Different From That Of Healthy Individuals?, Zeri̇n Özaydin Aksun, Seyda Erdoğan, Ayşe Kalkanci, Eli̇f Ayça Şahi̇n, Tuğba Çuhadar, H. Özden Şener

Turkish Journal of Medical Sciences

Background/aim: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. Several studies shown that alterations of microbiota, increase the risk of neurodegenerative disorders. We aimed to reveal whether there is a difference in the gut microbiota of patients with ALS.Materials and methods: The participants are divided into three groups. Group 1 formed patients with ALS. Healthy family members living in the same house of the patients formed Group 2. Lastly, sex, age-matched healthy people were included in Group 3. Fecal samples were collected in 15 mL falcon tubes and stored at -80 °C. Genomic DNA isolation was performed on samples. …

Distribution And Classifications Of Pkhd1 Gene Variants In Turkish Population With Next Generation Sequencing Method, Yüksel Gezgi̇n, Berkay Kirnaz, Rauf Baylarov, Afi̇g Berdeli̇

Turkish Journal of Medical Sciences

Background/aim: Autosomal recessive polycystic kidney disease is an inherited kidney disease. This study aims to detect rare and common DNA variants of the PKHD1 gene using next-generation sequencing (NGS) and to classify them in terms of being pathogenic according to The American College of Medical Genetics and Genomics. Materials and methods: NGS analysis was performed on the DNA of 304 patients who were referred to Ege University Molecular Medicine Laboratory with suspected polycystic kidney disease. Results: As a result, a total of 82 different DNA variants, 16 of which were novel, were detected. The breakdown of the variants found is …

The Association Between Vigour And Flexibility With Injury And Alertness During Shift Work, Lee Di Milia, Janet L. Barnes-Farrell, Rick A. Laguerre, Simon Folkard

Management Faculty Research and Publications

Models of shift work and health suggest that individual differences in circadian rhythm characteristics may moderate the relationship between night shift work and injury, but this argument has not been directly tested. In this study, we tested the efficacy of two circadian rhythm characteristics—vigour and flexibility—as moderators of the path between shift work and injury. In addition, we aimed to replicate the association between vigour, flexibility, and alertness by time of day, and the measurement properties of the Circadian Type Inventory. We recruited 401 healthcare workers from Australia and Great Britain. After controlling for confounding variables, the results showed that …

A Bioarchaeological Overview Of The Late Woodland Period Gooden Mound Group, Fulton County, Illinois, Aaron M. Durchholz

Theses and Dissertations

Extensive research in paleopathology has documented adverse effects accompanying a shift in subsistence strategy from largely nomadic, hunting and gathering lifestyles to those of more sedentary, agrarian systems. Comparative assessment of the human skeletal remains of early foragers and later farmers recovered from archaeological sites around the world have consistently demonstrated a decrease in average age at death in the latter.

Across the pre-Columbian North American Midwest, the transitional period between the Late Woodland and Mississippian periods, sometimes referred to as the terminal or Mississippian Acculturated Late Woodland, portended establishment of semi-permanent to permanent hamlets, increasingly reliant upon the adoption …

Pressing Toward Progress: A Phenomenological Study Exploring Perceptions Of Wellness Among Black Female Non-Traditional Students, Stacey Wiggins

Theses and Dissertations

Black female nontraditional student enrollment is increasing. Black women have higher rates of preventable stress related health issues than their white counterparts. While they have shown endurance and resilience to pursue their degree, it can jeopardize their wellness. This study provides an understanding of how this population perceives their wellness and what can be done to help them matriculate higher education without violating their wellness.

Applications Of Physics-Informed Graph Neural Networks In Wind Farm Layout Optimization, Emma R. Martin

Theses and Dissertations

Rapid advancements in data-driven deep learning models have led to their increased usage in recent years. Highly-effective models for conducting complex decision-making tasks have been developed. Given their success, data-driven deep learning models are being developed and improved in a variety of areas, one of which is renewable energy. In this thesis, we discuss the development of data-driven, deep learning models for optimizing wind farm layouts for maximum power output. We include a background for wind energy, the physics of fluid flow and power production, and two types of neural networks: graph neural networks and physics-informed neural networks. Additionally, we …

An Exploration Of Menopause: Young People's Perceptions Of Women In Menopause (Study 1) And Menopausal Women's Self-Reports Of Their Experiences (Study 2), Fiona Therese Fleming

Theses and Dissertations

Menopause is a transitional phase in a woman’s life, and society is filled with negative stereotypes of women in menopause. Menopause is a difficult period for many women due to hormonal fluctuations, changes in their bodies, and various other health effects. The negative stereotypes of menopause in the media can cause the general public to hold negative perceptions regarding menopausal women (Gannon and Stevens 1998). The purpose of my two-part study was to extend prior research surrounding perceptions of menopause and look specifically at young people’s perceptions of women in menopause, as well as women’s experiences with menopause.

Study 1 …

Microaggressions And Their Impact On The Neurodiverse College Experience, Audre J. Knecht

Theses and Dissertations

Previous literature indicates that people with invisible disabilities (including neurodiversity) are at an increased risk of ableist microaggressions, especially on college campuses. Neurodivergent college students (N=13) were interviewed about their college experiences at a midwestern university in the United States. While only a few students reported experiencing microaggressions, there were overall themes of mistreatment from their instructors, watching other students experience microaggressions, feelings of depression, anxiety, and hopelessness, and the desire to mask neurodivergent traits to feel accepted at their university.

It’S Giving Genocide: What Feminist Theory, Indigenous Thought, And Queer Theory Have To Say About Climate Change, Owen George

MS in Environmental Studies Master's Theses

Climate change is having profound impacts on communities around the world. In some cases, and with time, more and more, the impacts of climate change are happening on a level that constitutes genocide. Raphaël Lemkin’s and Claudia Card’s definitions of genocide are most applicable to climate change as they have broader understandings of victim groups and social death, and they recognize that inaction to prevent reasonably foreseeable harm constitutes genocidal intent. The UN’s more rigid definition does, to a lesser extent, also apply to climate change. Across the three definitions examined here, the argument of climate change as genocide is …

Enzymatic And Ultrasound-Assisted Extraction Of Bioactive Triterpenoids From Centella Asiatica, Zue Zue Win Myat

Chulalongkorn University Theses and Dissertations (Chula ETD)

Centella asiatica (L.) Urban, commonly known as gotu kola or bua-bok in Thai, is a medicinal herb valued for its rich content of pharmacologically active triterpenoids, notably asiaticoside, madecassoside, asiatic acid, and madecassic acid. These compounds contribute to a range of therapeutic effects, including wound healing, antioxidant, anti-inflammatory, antibacterial, and neuroprotective activities. However, conventional extraction methods such as maceration and Soxhlet extraction are often constrained by long processing times, high solvent usage, and low extraction efficiency. To address these limitations, this study investigates an integrated green extraction strategy that combines enzymatic pretreatment with ultrasound-assisted extraction (UAE) for the efficient recovery …

การต่อรองอัตลักษณ์และสิทธิของกลุ่มชายขอบในอินเดียร่วมสมัย กรณีศึกษา Gangubai Kathiawadi และกลุ่มฮิจรา, นภัสสร ณ นคร

Chulalongkorn University Theses and Dissertations (Chula ETD)

สารนิพนธ์ฉบับนี้มีวัตถุประสงค์เพื่อวิเคราะห์และเปรียบเทียบการนำเสนอภาพลักษณ์ของกลุ่มฮิจราในภาพยนตร์ Gangubai Kathiawadi กับความเป็นจริงทางสังคมของอินเดียร่วมสมัย โดยอธิบายผ่านกรอบแนวคิด Constructivism ที่มองว่าอัตลักษณ์ไม่ใช่สิ่งตายตัว แต่ถูกสร้างและปรับเปลี่ยนผ่านกระบวนการทางวัฒนธรรมและปฏิสัมพันธ์กับโครงสร้างทางสังคม สารนิพนธ์ฉบับนี้พบว่า แม้ในภาพยนตร์ตัวละครฮิจรามีอำนาจทางสังคมและการเมือง แต่อัตลักษณ์ดังกล่าวเป็นเพียงสัญลักษณ์ “ภาพแทนเชิงอุดมคติ” ที่ตอกย้ำภาพจำที่สังคมคุ้นเคย ตรงข้ามกับความเป็นจริงที่กลุ่มฮิจราถูกกดทับจากโครงสร้างอำนาจที่ไม่เท่าเทียม ทั้งในด้านเศรษฐกิจ การจ้างงาน การศึกษา และการเข้าถึงสวัสดิการ แม้รัฐอินเดียจะประกาศรับรองสถานะ “เพศที่สาม” อย่างเป็นทางการตั้งแต่ปี ค.ศ. 2014 สื่อบันเทิง Bollywood มีบทบาทสำคัญในการหล่อหลอมทัศนคติของสังคมและสร้าง soft power ผ่านแพลตฟอร์ม Netflix ซึ่งช่วยให้ภาพลักษณ์ของกลุ่มฮิจราได้รับความสนใจในระดับสากล แต่สื่อกระแสหลักไม่สามารถก้าวข้ามอคติเดิมได้ เนื่องจากฮิจรามักถูกนำเสนอในฐานะ “ตัวละครเสริม” ดังนั้น การต่อสู้ของกลุ่มชายขอบในอินเดีย ไม่ว่าจะเป็นโสเภณีในอดีตหรือกลุ่มฮิจราในปัจจุบัน ไม่ได้เป็นเพียงการเรียกร้องสิทธิทางกฎหมาย แต่เป็นการต่อสู้กับค่านิยมและโครงสร้างสังคมที่หยั่งรากลึกที่ต้องอาศัยเวลา ความพยายาม และความร่วมมือจากหลายฝ่าย เพื่อส่งเสริมให้เกิดความเท่าเทียมอย่างยั่งยืน