Digital Commons Network^™

Climate Law In The 21st Century: An Analysis Of Climate Legislation And Its Role In Mitigating The Emerging Issue Of Climate Refugees, Chloe Giacalone.

Plymouth Law Review

As global warming worsens, the consequences of climate change are becoming more severe. With its consequences going beyond the natural environment. Climate change is now having adverse effects on vulnerable populations most affected by climate change. This article aims to look at whether climate law has the potential to reduce human displacement. Treaties such as The United Nations Framework Convention on Climate Change and the Paris Agreement will be analysed to look at the international efforts to reduce climate change and whether they have the potential to mitigate climate change and climate refugees. As there is no definition of a …

Lysophosphatidylcholine Acyltransferase-2 (Lpcat-2) & Protein S-Acylation In Macrophage Innate Immunity, Christian Good

School of Biomedical Sciences Theses

Lysophosphatidylcholine acyltransferase (LPCAT)2 is an enzyme involved in remodelling glycerophospholipids within cell membranes and the generation of platelet-activating factor. LPCAT2 also mediates lipopolysaccharide (LPS)-induced cytokine responses in both murine and human macrophages. Investigations into the mechanism behind LPCAT2 involvement into LPS-induced cytokine responses identified that LPCAT2 translocates to membrane lipid raft domains and associates with toll-like receptor (TLR)4 following activation by LPS. The mechanism behind this is not known, however LPCAT2 appears to have a role in regulating innate immune responses via lipid raft signalling complexes and understanding the molecular details of these mechanisms could help in the development of …

Passive Sampler Derived Profiles And Mass Flows Of Perfluorinated Alkyl Substances (Pfass) Across The Fram Strait In The North Atlantic, Matthew Dunn, Simon Vojta, Thomas Soltwedel, Wilken-Jon Von Appen, Rainer Lohmann

Graduate School of Oceanography Faculty Publications

Per- and polyfluorinated alkyl substances (PFAS) are a family of pollutants of high concern due to their ubiquity and negative human health impacts. The long-range marine transport of PFAS was observed during year-long deployments of passive tube samplers in the Fram Strait across three depth transects. Time weighted average concentrations ranged from 2.4 to 360 pg L^–1, and 10 different PFAS were regularly observed. PFAS profiles and concentrations were generally similar to those previously characterized for polycyclic aromatic hydrocarbons (PAHs) at these sites. The detection of several anionic PFAS in “old” water demonstrated that they are not perfect …

Honors In Practice, Volume 20, 2024: About The Authors, National Collegiate Honors Council

Honors in Practice Online Archive

JUDY ALBAKRY serves as an adjunct professor and honors advisor at Middle Tennessee State University. She also coordinates the Buchanan Transfer Fellowship Program in the honors college. Her research specializes in student success initiatives, high-impact practices, transfer student engagement, and program assessment.

Bridgewater Magazine, Volume 34, Number 1, Spring 2024, Bridgewater State University

Bridgewater Magazine

Lighting the Way: the nation's last lighthouse keeper and first woman in that role, Sally Snowman, '76. Also in this issue: The multiple sides of climate change; A program that helps students with an autism spectrum disorder or related social profile gain real-world experience; an article on Peter Weyand, G'88; Two decades of The Bridge; and eclipsing expectations: on-campus viewing event draws hundreds to BSU, observatory.

Nekton Community Responses To Living Shoreline Restorations In Alabama, Shelby Kuck, Christopher Grant, Matheus De Barros, Alexandra Rodriguez, Ronald Baker

Gulf and Caribbean Research

No abstract provided.

Fusion And Integration Pipelines For Optical And Chemical Imaging Data For Clinical Interpretation In Ex-Vivo Diagnosis, Mohd Rifqi Rafsanjani, Karin Jirstrom, Arman Rahman, Jochen H.M. Prehn, William Gallagher, Aidan D. Meade

Conference Papers

In the realm of ex-vivo diagnosis, the integration of optical and chemical imaging data has emerged as a transformative approach, offering a comprehensive understanding of biological specimens at a molecular level. Chemical imaging of human tissue specimens provides an all-digital label-free approach to imaging in objective histopathology, though it requires reference to gold standard pathological (e.g. haematoxylin and eosin (H+E) stained) images for pathological interpretation. Optical imaging techniques, such as microscopy and spectroscopy, provide detailed spatial information, capturing morphological features with high resolution. Concurrently, chemical imaging methods, including mass spectrometry and Raman spectroscopy, offer insights into molecular composition. The challenge …

Data For Context-Dependence Of An Antipredator Response In Neotropical Harvestmen (Arachnida: Opiliones), Austin Calhoun, Rachel Bowden, Ben Sadd

Faculty Publications – Biological Sciences

Inducible defence strategies evolve in response to temporally and spatially variable predation risk. Selection should favour the expression of these strategies when risk crosses a threshold, but expression may also depend on how effective a given strategy is across different contexts (e.g., social environment). For neotropical harvestmen, aggregation behaviour has been shown to be a group-level defence strategy but can be supplemented by additional behaviour to enhance antipredator defence. A secondary behavioural strategy termed “bobbing” has been documented as being associated with gregarious behaviour, in which individuals rapidly move their bodies up and down. This strategy has been proposed to …

Warwilding: A Weapon And A Shield In The Midst Of Conflict, Lynn Ma

UC Law Environmental Journal

War disrupts the lives of people, governments, and the wider environment. The purpose of this article is to examine how rewilding and ecological planning could be applied to military logistics to enhance peace and security amid war and post-war periods. This is explored through a concept that conservationists have coined “WarWilding.” I will develop my conclusions by analyzing WarWilding case studies from active warfare and post-war zones. To evaluate the boundaries in the ethics of WarWilding, this paper will frame the analyses around provisions in the Convention on the Prohibition of Military or Any Other Hostile Use of Environmental Modification …

Carbon Storage Capacity Of Forests In New Jersey, Charles R. Harman, Meiyin Wu, Paul Bovitz, Elizabeth Ravit, Elizabeth Burke Watson, Daniel Gimenez

New Jersey Center for Water Science & Technology Reports

This report of the NJ Science Advisory Board Ecological Processes Standing Committee (EPSC) addresses charge questions focused on researching how the NJ Department of Environmental Protection might manage issues related to carbon content found within soil and its relationship to climate change. Whereas forests of New Jersey play a critical role in sequestering carbon which plays a direct role attempts to combat climate change, our forests are under constant pressure from a variety of natural and anthropogenic factors including damaging insects, overpopulation of browse species such as white-tailed deer, the influx of invasive plant species and impacts from development. The …

Harmful Algal Bloom Lake Management Guidance, Mike Danko, Jason Adolf, Chris Doyle, Nicole Fahrenfeld, Bob Kortmann, Fred Lubnow, Ling Ren, Nathan Ruhl, Stephen Souza, Meiyin Wu

New Jersey Center for Water Science & Technology Reports

Executive Summary: In 2021, the Division of Water Monitoring and Standards and Pesticide Control (DWMSPC) and the New Jersey Sea Grant Consortium (NJSGC) recruited a team of lakes management and cyanobacterial HAB experts to address the second component of the Governor’s HAB initiative focusing on enhancing scientific expertise and building the state’s capacity for HAB response. The HAB Expert Team’s primary objective is to provide guidance to DEP on HAB prevention, mitigation and management for NJ lakes and other waterbodies. The team has compiled a comprehensive literature review as a resource guide available here: NJDEP | Harmful Algal Blooms | …

Advancing Cancer Classifcation Through Machine Learning Analysis Of Rna-Seq Gene Expression Data, Emil Agbemade, Amina Issoufou Anaroua, Dimitri Bamba

Data Science and Data Mining

This study delves into the classifcation of various cancer types using the RNA-Seq (HiSeq) PANCAN dataset from the UCI Machine Learning Repository, which encompasses a rich collection of gene expression data across multiple tumor samples. To improve cancer diagnosis and treatment, our methodology confronts the challenges inherent in high-dimensional datasets, such as the Hughes Effect and the Curse of Dimensionality, through innovative feature selection methods and machine learning approaches. A key component of our strategy includes the use of tree-based algorithms, particularly Random Forest, to refine the dataset to seventy genes of utmost relevance for tumor classifcation, and the application …

Predicting Telecommunication Customer Attrition Using The Hopfeld Neural Network Model., Benedict Kongyir, Emil Agbemade, Kelvin Njuki

Data Science and Data Mining

Customer churn prediction has become one of the crucial steps for customer retention. Telecommunication companies rely on loyal customers to make their proft. It is often very easy for customers to switch from one service provider to the other. To prevent or reduce the rate of customer attrition, there needs to be a model that can identify customers who are at risk of churning in the future in advance. Previous literature has shown that predictive models are efective in predicting customer churn. In this work, four tentative machine-learning models are built using data obtained from Kaggle on telecommunication customer attrition …

Structural Modification Of 4'-Aminochalcones As Α-Glucosidase Inhibitors, Emmanuel Sunday Idoko

Chulalongkorn University Theses and Dissertations (Chula ETD)

Diabetes mellitus, one of the most predominant health problems worldwide, characterized by hyperglycemia, has attracted the attention of medicinal chemists. Although several therapeutic drugs have been developed and used clinically, diabetes continues to pose a growing threat to public health. One of the promising approaches for treating type 2 diabetes involves reducing the rate of carbohydrate hydrolysis by inhibiting the action of α-glucosidase. Over the years, chalcone analogues have been reported for their vast biological properties and as a promising antidiabetic agent. In this research, two series of 4'-aminochalcone derivatives were designed and synthesized as α-glucosidase inhibitors. Twenty-five alkylated 4'-aminochalcone …

High Purity Silver Nano- And Micro Particles With Controllable Shapes By Polymeric Stabilizers, Natsuda Muankhajorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

This work presents a rapid, sustainable, and efficient technique for both recovering silver microstructures from spent button batteries and fabricating flexible conductive materials. In the first phase, a green recovery method was developed using H2O2 as a reducing agent to convert silver sources into high-purity silver microstructures. The morphology of the recovered silver was controlled using polymeric stabilizers (PVP and PVA) whose molecular weights significantly influenced particle shape and aggregation. PVP promoted the formation of uniform silver microplates, while PVA yielded isotropic microspheres. The silver microstructures from the spent button batteries were converted into highly pure silver microstructures (>98%), …

Juvenile Dungeness Face High Predation Risk From Green Crabs Across Increased Temperatures At Different Salinities, Trever Gelling

Environmental Science and Management Undergraduate Departmental Honors Theses

Marine heatwaves, altered precipitation regimes, and other changing climate conditions are altering the abiotic conditions of Oregon's estuaries. Furthermore, warmer water temperatures are correlated with the range expansion and population growth of the invasive and broadly tolerant Carcinus maenas, the green crab, in Oregon. Metacarcinus magister, Dungeness crab, one of Oregon’s most valuable fishery species, is also facing these climate stressors, and their young that recruit to estuaries overlap with C. maenas adults. Therefore, we wanted to determine impacts of C. maenas on young-of-the-year (YOTY) M. magister and the roles of salinity, temperature, and predator size in mediating …

Translational Neuroscience Contributes To Understanding Neurodevelopmental Outcomes Of Dostoyevsky's "Brothers Karamazov" With Treatment Implications, Stephen I. Deutsch, Jessica A. Burket, Jeffrey Elikan Jd, David R. Spiegel

Department Psychiatry & Behavioral Science Faculty Publications

Dostoyevsky's novels raise profound ethical, moral, philosophical and theological issues and, as a result, both he and his novels serve as fertile subjects of scholarly inquiry across a variety of academic disciplines. In particular, major characters in "The Brothers Karamazov" lend themselves to classical psychodynamic formulations, such as the influence of adverse childhood experiences on adult social and occupational outcomes, which in the case of Dmitry, the eldest son of Fyodor Pavlovich Karamazov, are considered in exquisitely fine detail. Prosecutor and defense attorney provide differing interpretations of how early traumas, largely due to paternal neglect and abuse, affected Dmitry's adult …

Intracerebral Benign Fibrous Histiocytoma, Liusong Yang, Mingzhe Zheng, Yingfeng Zhu, Zhongqing Chen

Neurosciences

Benign fibrous histiocytoma (BFH) within the intracerebral region is remarkably rare. Our report details 2 cases of unusual BFH instances that exhibit no adhesion to the dura mater or cerebral falx, accompanied by a comprehensive literature review. While magnetic resonance imaging demonstrates specific characteristics for BFH, it does not readily differentiate BFH from more common brain neoplasms like gliomas and metastatic tumors. The definitive diagnosis of BFH depends primarily on histopathological and immunohistochemical examinations. Total surgical resection is considered an efficacious therapeutic approach, emphasizing the necessity for prolonged postoperative surveillance to detect any potential tumor recurrence or metastasis.

Ot '22 And The Path Of Administrative Law, Ilan Wurman

Articles

This symposium piece reflects on the Supreme Court’s October 2022 term and what it reveals for the direction of administrative law. It argues first that the nondelegation doctrine is dead but not for the reason functionalists have been arguing for so long. It is dead rather because the causes of its revival have been effectively removed. Nondelegation concerns are most felt when there is significant executive unilateralism; in the past such unilateralism was encouraged by the Chevron doctrine, which allows the executive branch to interpret statutes creatively and, so long as those interpretations are plausible, requires courts to defer to …

Legal Endearment: An Unmarked Barrier To Transforming Policing, Public Safety, And Security, Emmanuel Mauleón

Articles

The problems of racialized policing have come into renewed focus over the past decade. The advent of viral bystander videos has not only forced a popular confrontation with moments of both routine and extraordinary policing violence but also sparked protests, uprisings, and grassroots movements to challenge current practices in policing and determine what must be done to transform it. And yet, even after the mobilization of one of the largest racial justice movements in American history, transformative change remains elusive. This Article offers an answer to this puzzle by foregrounding White people’s collective relationship with policing and describing how this …

Fatherhood, Family Law, And The Crisis Of Boys And Men, June Carbone, Clare Huntington

Articles

Boys and men in all racial and ethnic groups and across most socioeconomic groups are struggling on many fronts, including education, employment, physical and mental health, and social integration. In these areas and more, boys and men are much worse off than they were only a few decades ago. The crisis—which is concentrated among men without college degrees—is rooted in large-scale structural changes to the economy that have decimated jobs for this group and policy choices that emphasize incarceration while doing little to address economic inequality.

The decline in male well-being is not just a problem for boys and men. …

Planning For Pandemic And Epidemic-Related Scarcity Of Medicines, Sapna Kumar

Articles

This chapter proposes an ex ante approach to tackling drug scarcity. Entities funding pandemic- and epidemic-related research should contractually require recipients to produce sufficient quantities of resulting medicines. The recipient would agree in the event of a future shortage to share its technology and know-how with a qualified third-party manufacturer, in exchange for compensation. Alternatively, funding entities could more broadly utilize dormant licenses, which activate in the event of a pandemic or epidemic, and which require rights holders to license out technology and know-how to alleviate shortages. Such provisions could go even further, integrating reasonable pricing assurances and ensuring access …

Expert Stakeholder Perspectives On Emerging Technology For Neuroimaging Research With Highly Portable Mri: The Need For Guidance On Ethical, Legal, And Societal Issues, Molly K. Madzelan, Frances Lawrenz, Susan Wolf, Francis X. Shen

Articles

Portable MRI (pMRI) technology, which promises to transform brain imaging research by facilitating scanning in new geographic areas and the participation of new, diverse populations, raises many ethical, legal, and societal issues (ELSI). To understand this emerging pMRI ELSI landscape, we surveyed expert stakeholder views on ELSI challenges and solutions associated with pMRI research.

Introduction: Revolutionizing Neuroimaging Research With Highly Portable Mri: Confronting Ethical And Legal Challenges, Francis X. Shen, Frances Lawrenz, Susan M. Wolf

Articles

No abstract provided.

The Rise Of Counter-Terrorism And The Demise Of Human Rights, Fionnuala Niaolain

Articles

This lecture addressed the consolidation and expansion of counter-terrorism norms and institutions since 9/11. The rise of counterterrorism has enabled the consolidation of autocracy, sustained democratic backsliding and undermined the capacity of civil society to function across the globe. The impact on human rights has been extensive and highly detrimental to the most vulnerable individuals and groups across the world. Drawing on my work as United Nations Special Rapporteur on Counter-Terrorism and Human Rights since my 2017 appointment, the lecture shows the hard choices that must be made nationally and globally to reverse these trends.

Long-Term Cardiometabolic Effects Of Preconceptional And Prenatal Opioid Exposure In The Adult Offspring, Nermin Hassan Mohamed Selim Ahmed

Theses and Dissertations--Pharmacology and Nutritional Sciences

Opioid use disorder (OUD), one of the greatest public health threats in the US, requires urgent attention. In 2022, the CDC reported 107,941 overdose deaths, over 70% attributed to synthetic opioids such as fentanyl (FEN). An alarming increase in opioid use disorder (OUD) diagnoses in pregnant people resulted in a 5-fold rise in cases of neonatal opioid withdrawal syndrome (NOWS). This condition elicits sympathetic overactivity, neural hyperexcitability, and a stress reaction characterized by tachycardia and hypertension. Whether prenatal exposure to fentanyl induces cardiovascular dysfunction in the offspring remains undetermined, impeding the timely development of strategies to mitigate OUD-related health risks …

The Impact Of Dissolved Organic Matter On Photodegradation Rates, Byproduct Formations, And Degradation Pathways For Two Neonicotinoid Insecticides In Simulated River Waters, Josephus F. Borsuah, Tiffany L. Messer, Daniel D. Snow, Steven D. Comfort, Shannon Bartelt-Hunt

UK CARES Faculty Publications

The influences of dissolved organic matter (DOM) on neonicotinoid photochemical degradation and product formation in natural waters remain unclear, potentially impacting the sustainability of river systems. Therefore, our overall objective was to investigate the photodegradation mechanisms and phototransformation byproducts of two neonicotinoid pesticides, imidacloprid and thiamethoxam, under simulated sunlight at the microcosm scale, to assess the implications of DOM for insecticide degradation in rivers. Direct and indirect photolysis were investigated using twelve water matrices to identify possible reaction pathways with two DOM sources and three quenching agents. Imidacloprid, thiamethoxam, and potential degradants were measured, and reaction pathways identified. The photodegradation …

Physiological Adaptation/Phenotypic Plasticity: A Vital Core Concept From The Medical And Health Care Perspective, Thad E. Wilson, Kristen Metzler-Wilson

UK CARES Faculty Publications

No abstract provided.

Feeding Systems And Fresh Lamb Color Stability, Koushik Mondal

Theses and Dissertations--Animal and Food Sciences

Consumers consider the surface color of fresh lamb as the indicator of freshness and wholesomeness, which affects their purchase decisions. The redox chemistry of myoglobin (Mb) determines the color of fresh lamb. Artificial raising on milk replacer (a pre-weaning strategy) as well as red clover supplementation are management strategies used in lamb production. This thesis focuses on the effects of artificial raising on milk replacer and red clover supplementation on the color and oxidative stability of fresh lamb.

In the first experiment, the effect of pre-weaning with milk replacer on the carcass attributes, color stability and lipid oxidation of lamb …

A Breast Cancer Stem Active Cobalt(Iii)-Cyclam Complex Containing Flufenamic Acid With Immunogenic Potential, Jiaxin Fang, Owamagbe N. Orobator, Chibuzor Ngozi Olelewe, Ginevra Passeri, Kuldip Singh, Samuel G. Awuah, Kogularamanan Suntharalingam

Chemistry Faculty Publications

The cytotoxic and immunogenic-activating properties of a cobalt(III)-cyclam complex bearing the non-steroidal anti-inflammatory drug, flufenamic acid is reported within the context of anti-cancer stem cell (CSC) drug discovery. The cobalt(III)-cyclam complex 1 displays sub-micromolar potency towards breast CSCs grown in monolayers, 24-fold and 31-fold greater than salinomycin (an established anti-breast CSC agent) and cisplatin (an anticancer metallopharmaceutical), respectively. Strikingly, the cobalt(III)-cyclam complex 1 is 69-fold and 50-fold more potent than salinomycin and cisplatin towards three-dimensionally cultured breast CSC mammospheres. Mechanistic studies reveal that 1 induces DNA damage, inhibits cyclooxygenase-2 expression, and prompts caspase-dependent apoptosis. Breast CSCs treated with 1 exhibit …