Digital Commons Network^™

A Health Justice Approach To Abortion, Maya Manian

Health Matrix: The Journal of Law-Medicine

No abstract provided.

Attitude Changes Among College Students Post-Pandemic, Alex J. Goncalo, Nicholas S. Zambrotta

Modern Psychological Studies

The COVID-19 pandemic forced students across the nation to attend school virtually and thus dramatically altered the college experience for many students. Stay at home mandates and loss of social interaction may have contributed to increased isolation and poor mental health. Although mandates have been lifted, and normal college life has resumed in most places, it is unknown if a lingering social impact was left on college students. Numerous studies provide evidence through in-depth examinations indicating altered mental health and psychological behavior of adults, specifically college aged individuals. The present study measured happiness, optimism, and psychological well-being in a sample …

Documented Outcomes Of Informal Caregivers Delivering Home-Based Interventions To Persons Living With Dementia: A Scoping Review, Andrea H. Meller

Social Work Theses - Archive

Most people living with dementia in the United States reside at home with informal caregivers. Yet research regarding non-pharmacological interventions for persons living with dementia is mainly conducted in institutional settings. Also, research into the impacts of interventions for persons with dementia on informal caregivers is scarce. This scoping review aims to map the breadth of literature on outcomes of informal caregivers delivering home-based interventions to people with dementia through the lens of the stress process model. Using the Arskey & O’Malley framework, an initial database search yielded 3,977 studies of which 22 were included in this review. Results revealed …

Exploring The Process Of Seeking Informal Social Support For Intimate Partner Violence Among African Immigrants Residing In The United States, Ricka Olga Mammah

Social Work Dissertations - Archive

Intimate partner violence against women is a pervasive global issue. For African immigrants in the United States, IPV continues to be a social problem, with many survivors seeking support from their informal networks. Informal networks refer to the social connections and relationships that individuals have outside of formal or professional settings, such as family members, friends, and acquaintances who provide emotional, practical, and social support. However, various cultural, religious, social, and legal barriers can make seeking informal social support for IPV challenging. To improve interventions designed to reach this vulnerable population, more inquiry is needed into how African immigrant survivors …

The Validity Of Trade Restrictions On Artificial Intelligence Technology Under The General Agreement On Tariffs And Trade's National Security Exception, Isabelle Brundieck

American University International Law Review

This Comment argues that the U.S. restrictions on the export of semiconductors and other AI technology to China do not violate the General Agreement on Tariffs and Trade 1994 (GATT 1994). Instead, such measures are legitimate expressions under GATT 1994’s Article XXI national security exception, which allows a country to break other articles within the agreement if necessary to protect the country’s essential national security interests. Given the national security risks associated with the rise of AI technology and the likelihood that such technology will be supplied to a military enterprise, the current trade restrictions qualify for the exception. However, …

Amnesty Laws In Modern Peace Agreements: An Analysis Of The Northern Ireland Legacy Act Under International Law, Mckenzie Gallagher

American University International Law Review

In September 2023, the United Kingdom passed the Northern Ireland Troubles (Legacy and Reconciliation) Act (“Legacy Act”), which grants amnesty to anyone who discloses information regarding murders, disappearances, or other unsolved crimes during the period known as “The Troubles” in Northern Ireland. The Legacy Act’s amnesty provision is expected to hinder the peace process in Northern Ireland and in turn, avert accountability for serious international crimes. This Comment considers to what extent the Legacy Act’s amnesty provision violates the Good Friday Agreement, the peace accord ending decades of conflict in Northern Ireland, the European Convention on Human Rights, the United …

Seed Patents: Enabling Innovation Beyond Biological Deposits, Ellaina Sanders

American University Law Review

In J.E.M. Ag Supply, Inc. v. Pioneer Hi-Bred International, Inc., the Supreme Court held that new sexually reproducing plant varieties are patentable subject matter. This allowed breeders and seed companies to protect their intellectual property in new seeds by obtaining utility patents so long as they meet the other statutory requirements, such as enablement. Unlike other intellectual property protection for new plant varieties, utility patents require the patent disclosure to include enough information that a person of ordinary skill in the art could make and use the invention without undue experimentation. In In re Wands, the Federal Circuit …

An Efficient And High-Throughput Method For The Evaluation Of Mitochondrial Dysfunction In Frozen Brain Samples After Traumatic Brain Injury., Hemendra J Vekaria, Olivia J. Kalimon, Paresh Prajapati, Gopal V. Velmurugan, Patrick G Sullivan

Neuroscience Faculty Publications

Mitochondrial function analysis is a well-established method used in preclinical and clinical investigations to assess pathophysiological changes in various disease states, including traumatic brain injury (TBI). Although there are multiple approaches to assess mitochondrial function, one common method involves respirometric assays utilizing either Clark-type oxygen electrodes or fluorescent-based Seahorse analysis (Agilent). However, these functional analysis methods are typically limited to the availability of freshly isolated tissue samples due to the compromise of the electron transport chain (ETC) upon storage, caused by freeze-thaw-mediated breakdown of mitochondrial membranes. In this study, we propose and refine a method for evaluating electron flux through …

Dentists’ Accounts Of Interpersonal Interactions Three Decades After The Postmortem Identification Of The Branch Davidians, Melissa Izuagbe

Psychology Theses - Archive

Despite extensive research on the psychological effects of mass disasters on survivors, the positive outcomes for volunteers and forensic workers, along with coping strategies to alleviate job-related stress, remain understudied. Self-disclosure and social support play pivotal roles in mitigating stress and fostering positive outcomes. This study employed interpretative phenomenological analysis to describe dentists’ experiences of self-disclosure and social support through the 31 years since conducting the postmortem identifications following the Branch Davidian Tragedy. The study was preregistered on the Open Science Framework (OSF) to promote transparency in research. We interviewed a subset (N = 14) out of the 50 dentists …

Unusual Eluents, Small Systems, And Digital Signal Processing For Highly Efficient Greener Separations, Troy T. Handlovic

Chemistry & Biochemistry Dissertations - Archive

Separation science is a rapidly evolving field, where routine analyses are now done at speeds and efficiencies not thought to be possible several years ago. The tangential field of green analytical chemistry is evolving at an even faster rate and can be considered to be in its infancy stage. As green analytical chemistry is better understood, the greenness of a method will be considered during standard method development just as resolution, sensitivity, and efficiency are considered now. The first portion of this dissertation focuses on the development of mathematical and pragmatic methods to minimize the analytical method greenness score, and …

Total Synthesis Of Novel Core Modified Pleuromutilin Analogs And Studies Towards The Total Synthesis Of (€“)-Lomaiviticin A, Mikaela Mary Dibello

Yale Graduate School of Arts and Sciences Dissertations

In the first chapter, I describe the development of a modular synthetic route that allows for the de novo synthesis of novel pleuromutilin analogs, including analogs with modified cores. (+)-Pleuromutilin (11) is a diterpene fungal metabolite that displays moderate antimicrobial activity against Gram-positive pathogens. Semisynthetic modifications of 11 resulted in derivatives with improved activity and pharmacological properties. However, the majority of derivatization studies have focused on modifying the periphery of the molecule. Studies on the impact of structural modifications to the tricyclic core have been limited as this type of diversification is inaccessible via semisynthesis. Herein, I outline our development …

Undergraduate Bulletin 2024-2025, Cuny John Jay College

College Bulletins

Covers academic year 2024-2025

The Influence Of Ecoregions And Land Use/Land Cover On Fish Assemblages In Southern Minnesota, Masaki Hara

All Graduate Theses, Dissertations, and Other Capstone Projects

Level III ecoregions of the conterminous United States provide a framework for facilitating environmental understanding and aiding environmental management practices. In southern Minnesota near Mankato, there are two level III ecoregions: to the east is North Central Hardwood Forest (NCHF) and to the west are Western Corn Belt Plains (WCBP). They contained a combined 104 fish species in local lakes. However, little is known about how land use and land cover affect fish assemblages in these lakes, which are indicator fish species, and if any invasive fish species are adversely impacting native fish populations. This study addresses these issues through …

Marielle Calanza Honors Portfolio, Marielle Calanza

Honors Capstone Portfolios

Marielle Calanza's Honors Porfolio captured in December 2024.

The Next Big Thing: What's Coming Next In Youth Ministry

Journal of Adventist Youth and Young Adult Ministries

No abstract provided.

The Protective Effect Of Astaxanthin On Scopolamine - Induced Alzheimer’S Model In Mice, Rania Magadmi, Sara Nassibi, Fatemah Kamel, Aziza R. Al-Rafiah, Duaa Bakhshwin, Maha Jamal, Mohammed Alsieni, Abdulhadi S. Burzangi, M. A. F Zaher, Mohammed Bendary

Neurosciences

Objectives: To investigate the fundamental mechanisms of the neuroprotective impact of Astaxanthin (AST) in a mouse model of Alzheimer’s disease (AD) induced by scopolamine. Methods: This research constituted an in vivo animal study encompassing 36 adult male mice, divided into 6 groups: Control, 100 mg/kg AST, 2 mg/kg scopolamine (AD group), 100 mg/kg AST+2 mg/kg scopolamine, 3 mg/kg galantamine+2 mg/kg scopolamine, and 100 mg/kg AST+3 mg/kg galantamine+2 mg/kg scopolamine. After 14 days, the mice’s short-term memory, hippocampus tissue, oxidative and inflammatory markers were evaluated. Results: The AST demonstrated a beneficial influence on short-term memory and a reduction in acetylcholinesterase activity …

Leveraging Multivariate Analysis And Adjusted Mutual Information To Improve Stroke Prediction And Interpretability, Moutasem S. Aboonq, Saeed A. Alqahtani

Neurosciences

Objectives: To develop a machine learning model to accurately predict stroke risk based on demographic and clinical data. It also sought to identify the most significant stroke risk factors and determine the optimal machine learning algorithm for stroke prediction. Methods: This cross-sectional study analyzed data on 438,693 adults from the 2021 Behavioral Risk Factor Surveillance System. Features encompassed demographics and clinical factors. Descriptive analysis profiled the dataset. Logistic regression quantified risk relationships. Adjusted mutual information evaluated feature importance. Multiple machine learning models were built and evaluated on metrics like accuracy, AUC ROC, and F1 score. Results: Key factors significantly associated …

Centralizing Pharmaceutical Innovation, Sapna Kumar

Articles

The United States has a mostly decentralized system for promoting new medicine development. By offering patents and regulatory exclusivities, the government incentivizes pharmaceutical companies to invent and bring to market new medicines. Although this development model offers benefits for promoting innovation, it comes at a cost: Market-based incentives lead companies to prioritize research and development (“R&D”) for medicines that offer a safe path to profitability, as opposed to those that offer the greatest social benefit. In particular, pharmaceutical companies are reluctant to invest in R&D for critically-needed antibiotics and infectious disease vaccines—both of which are difficult to develop and provide …

Media Art Community Festival Based On Local Culture In Indonesia : An Ethno-Pedagogy Perspective, Jeong Ok Jeon, Juju Masunah, Tri Karyono

Journal of Urban Culture Research

This study reviews the Indonesian government-led Festival Komunitas Seni Media (FKSM) or Media Art Community Festival in English from an ethno-pedagogical perspective to uncover its strategies for enhancing local cultural values. Using descriptive and historical approaches, data were collected through literature studies, participatory observation, document studies, and personal reflection, and analyzed thematically. The findings are: First, FKSM provides artists with opportunities to learn about the local host city’s culture as their creative inspiration (value of locality). Second, FKSM facilitates knowledge sharing between curators and local management for future festivals (value of continuity). Third, FKSM promotes inclusiveness by selecting host cities …

The Complex Protein Analysis Of Purified Extracellular Vesicles In The Study Of Colorectal Cancer, Renee Boone, Cecilia Osthoff

Science University Research Symposium (SURS)

Proteomics, the study of complex protein mixtures in which liquid chromatography-mass spectrometry (LC-MS) is used to analyze peptide sequences, is commonly utilized to study the double membrane, cell-derived vesicles known as exosomes. Exosomes are double membrane, cell-derived vesicles that contain cell components such as DNA, lipids, and proteins. They function to transport proteins and cellular materials between cells and are involved in the progression and metastasis of cancer. The impact of these extracellular vesicles on cancer spread can be analyzed using proteomics, through the purification of the proteins isolated from the vesicles. The purpose of our research is to analyze …

Examining The Synergy Of Curcumin And Cisplatin In Osteosarcoma Cells, Ellis Stafford

Science University Research Symposium (SURS)

Osteosarcoma is a type of bone cancer that is especially difficult to treat due to its ability to rapidly metastasize, with an average survival rate of 70% if caught before metastasis but 30% after metastasis. The current standard of treatment, if caught before metastasis, is surgery. However, after metastasis, cisplatin is the chemotherapy of choice, which is often ineffective. This study aims to improve treatment strategies by combining a chemotherapy, cisplatin, with curcumin. The supplement used for this study is curcumin, which is a biologically active ingredient in turmeric. Curcumin has shown promising effects in cancer treatment through its ability …

Effects Of Pugnac Treatment On Lysosomal And Mitochondrial Function In N27a Neurons, Mariam M. Salib, Emily A. Tadros

Science University Research Symposium (SURS)

Sanfilippo Syndrome (MPS III) is an autosomal recessive lysosomal storage disorder. This disease is prevalent in children at a young age. The gene that affects Sanfilippo is the HGSNAT gene which normally breaks down and recycles heparan sulfate, a large sugar molecule. Heparan sulfate accumulates and causes damage to the cells of the body, particularly in the brain and spinal cord by blocking normal lysosomal function. The buildup of heparan sulfate in brain and spinal cord cells leads to progressive neurological symptoms, including cognitive decline, movement disorders, and behavioral issues.

Previous work done in our lab showed that when we …

How Do Different Amounts Of Limestone Affect Plant Growth Of Radishes On A Green Roof?, Lauren A. Merrill, Chloe E. Sebaugh, Tytionne C. Bellamy, Madison L. Keller

Science University Research Symposium (SURS)

Limestone has been known to stimulate vegetative growth by neutralizing acidic soils and raising pH. In hopes of preserving plants that hold nutritional, cultural, and medicinal significance, such as radishes, green roofs are also becoming increasingly important resources. To maximize plant growth and space efficiency, this study examined the effects of varying amounts of limestone on radishes grown in a green roof environment. Radish seeds were planted in a variety of limestone conditions including 0 grams, 90.718 grams, 181.437 grams, and 272.156 grams of limestone. After two months, radishes were harvested and weighed to check for growth. The results suggest …

Analyzing The Belowground Biomass Of The Camp Wilkes Living Shoreline​, Ally Matheny, Wei Wu Dr., Makenzie Holifield

Science University Research Symposium (SURS)

By utilizing natural materials, living shorelines contribute to coastal resilience. While traditional concrete seawalls stabilize the land and reduce erosion, living shorelines do so too while also providing a variety of species with a place to live, maintaining or enhancing habitats, and improving the quality and flow of water. Living shorelines are made up of naturally occurring materials like plants, sand, shells and rocks. The Camp Wilkes’ Living Shoreline project entails building 150 linear feet of breakwater along Camp Wilkes’ south facing shoreline in the Back Bay of Biloxi, northwest in the city of Biloxi, Mississippi.

Advancing Genomics To Improve Health Equity, Ebony B. Madden, Lucia Hindorff, Vence Bonham, Tabia Akintobi, Esteban Gonzalez Burchard, Kellen E. Baker, Rene L. Begay, John D. Carpten, Nancy J. Cox, Valentina Di Francesco, Denise Dillard, Faith Fletcher, S. Malia Fullerton, Nanibaa' Garrison, Catherine Hammack-Aviran, Vanessa Hiratsuka, James E.K. Hildreth, Carol Horowitz, Chanita A. Hughes-Halbert, Michael Inouye, Amber Jackson, Latrice Landry, Rick Kittles, Jeff T. Leek, Nita A. Limdi, Nicole Lockhart, Elizabeth Ofili, Eliseo Perez-Stable, Maya Sabatello, Lorjetta Schools, Jennifer Troyer, Ben Wilfond, Genevieve Wojcik, Judy Cho, Sandra Soo-Jin Lee, Eric Green

Law Faculty Scholarship

This perspective article examines the relationship between human genomics research and health equity, highlighting persistent disparities in the design, participation, and implementation of genomic science. Although genomics has substantial potential to improve disease prevention, diagnosis, and treatment, the benefits of genomic advances have not been equitably distributed across populations. Historically, genomic research has disproportionately relied on datasets derived from individuals of European ancestry, resulting in limited generalizability of findings and the risk of exacerbating existing health disparities. Drawing on insights from a National Human Genome Research Institute (NHGRI) workshop and a targeted literature review, the authors identify key challenges and …

A Woman's Right To Change Her Mind: The Abortion Pill Reversal Debate, Kelsey Perault

Belmont Law Review

This Note examines the legal, medical, and ethical controversy surrounding abortion pill reversal (APR), a protocol involving the administration of progesterone after ingestion of mifepristone in an attempt to counteract a medication abortion. After outlining the scientific and regulatory history of mifepristone, misoprostol, and progesterone, the Note surveys emerging state legislation that either mandates disclosure of APR as part of informed consent or prohibits the practice altogether. It analyzes the debate within the frameworks of off-label prescribing, medical malpractice, informed consent doctrine, and right-to-try laws. The Note argues that if abortion is legally protected as an exercise of reproductive autonomy, …

Synthesis Of Cu-Cy Nanoparticles For Treating Pfas In Water, Ligang Wang

Physics Theses - Archive

This work aims to address the cumulative harm caused by perfluoroalkyl and polyfluoroalkyl substances (PFAS) in water to human health and the ecological environment around the world. Reducing or removing PFAS pollution is an urgent need. Cu-Cy nanoparticles are photosensitizers, which were developed for photodynamic therapy of cancer in the first place. In this work, we use Cu-Cy for the catalytic degradation of PFAS. Synthesis of Cu-Cy nanoparticles in deionized water at 90 degrees Celsius is a low-cost and efficient method. We demonstrated the detailed process of synthesizing Cu-Cy nanoparticles. Under ultraviolet illumination, the synthesized Cu-Cy nanoparticles turned yellow as …

Next-Generation Alpha Irradiation Platform: Design, Development, And Applications In Radiobiological Research, Harsh Arya

Physics Dissertations - Archive

This dissertation unveils the innovative design, development, and application of a next-generation alpha irradiation platform, specifically crafted for pre-clinical and university-level radiobiological research. Driven by the quest to overcome the inherent limitations of existing alpha particle irradiators, this study explores the profound therapeutic potential of alpha particles in cancer treatment. Known for their exceptional high linear energy transfer (LET), alpha particles exhibit a unique prowess in inducing clustered DNA damage, sparking intriguing possibilities for highly targeted cancer therapies. Yet, their application has been historically constrained by their limited range of biological tissues and the absence of precise delivery systems.

Our …

The Death Of Slim Shady: Eminem’S Lyrical Life Course Trajectory, Anthony Raul Rosales, Anthony R. Rosales

Criminology & Criminal Justice Theses - Archive

Eminem's lyrical life course trajectory helps provide insight into hip-hop and rap music's arguably criminal social stigma. Previous studies have examined Eminem's songs, but these topics focused on singular songs and themes rather than a lyrical life course. This study fills the gap by providing a content analysis of Eminem's solo studio albums, where it identifies themes and patterns that appear in the album's lyrics. The purpose of this study was to use research questions based on theory and previous research to examine Eminem's lyrics and personas. Using Eminem's thirteen solo studio albums consisting of two-hundred-nine songs, this study focused …

A Wearable Sensing System For High-Speed Interface Of Wide Range Electrochemical Sensor Array, Shanthala Lakshminarayana

Electrical Engineering Dissertations - Archive

Electrochemical sensing systems have emerged as indispensable tools in various fields due to their remarkable sensitivity, selectivity, and versatility. They play a pivotal role in modern research, industry, environmental monitoring, and healthcare devices. In environmental monitoring, these systems are deployed for detecting pollutants, heavy metals, and toxic gases, facilitating real-time monitoring, and ensuring environmental safety. Whereas, in the biomedical field, electrochemical sensing systems play a crucial role in diagnosing diseases, monitoring biomarkers etc, thereby revolutionizing healthcare practices.

Cost-effective wearable electrochemical sensing devices are significant for democratizing healthcare and improving public health outcomes. These devices enable continuous monitoring of physiological parameters, …