Digital Commons Network^™

How Leaf Size Affects Rate Of Leaf Litter Decomposition On A Greenroof, Douglass J. Lescher I, Makenzie T. Boylston, Faith A. Jackson, Leah Abraham, Darlene Panvini

Science University Research Symposium (SURS)

Leaf litter decomposition is an essential biological phenomenon that occurs within ecosystems, as it affects factors such as nutrient cycling, plant growth, soil fertility and other processes. Understanding the mechanisms that are attributed to leaf litter decomposition can help explain the role that leaf litter plays in ecosystems. A total of eight leaf litter bags were placed in environments of similar conditions on a green roof with the purpose of understanding how leaf size affects the rate of decomposition. The two species of variable size were coneflower (Echinacea tennesseensis, larger leaf) and baptisia (Baptisia australis, smaller …

The Rider (2024-11-11), Natalie Lapsley

The Rider Archives

Vol.10 No.12

Intouch Week Of November 11, 2024, New York Medical College

InTouch

• More than $16,000 Raised by NYMC SOM Marathon Runners
• Department of Pediatrics Hosts Leonard Newman, M.D. ’70, Assistant Professor Research Symposium
• Jonathan Fisher, Ph.D., Presents at the Neighborhood Science Seminar Series
• NYMC Community Visits New York Historical Society Museum
• NYMC SNMA Brings Hope to Tampa Residents Impacted by Hurricanes
• NYMC Blood Drive Brings Community Together to Save Lives
• Health Literacy Club Hosts Educational Vegetable Stand
• Student Spotlight: SOM Student Takes Second Place in International Neurosurgery Innovation Competition
• Faculty Spotlight: From Pupil to Professor: Alumni Lighting the Way at NYMC

On The Nature Of Regulating Medication Abortion: A Post-Dobbs Analysis On The Legality Of Emerging Efforts To Ban Federally Approved Mifepristone, Yann Kaufman

MC Law Review

No abstract provided.

A Fundamental Failing: The Mississippi Judiciary's Abrogation Of Its Constitutional Duty, Brad Robertson

MC Law Review

No abstract provided.

Enhancing Chemotherapy: Synergistic Action Of Cisplatin And Berberine Hydrochloride Against Osteosarcoma, Adam S. Al-Droubi, Andrea Florian

Science University Research Symposium (SURS)

Osteosarcoma, the most common type of bone cancer, is notably aggressive and prone to a rapid rate of metastasis. When the tumor is localized; the survival rate is approximately 76% and can often be treated with surgery. However, once metastasis occurs, the survival rate drops to 24% and must be treated with chemotherapy. The standard treatment for metastatic osteosarcoma typically involves combination therapeutics, with cisplatin being a key component despite its severe side effects. Unfortunately, osteosarcoma exhibits a natural resistance to chemotherapy driven by the overexpression of drug efflux pumps, DNA repair mechanisms, and apoptosis avoidance mutations. To address these …

Lotus Blossom: A Review Of Alan Hovhaness's Saxophone Music, Jason Todd Oates

Electronic Theses and Dissertations Archive

This dissertation provides saxophonists with a complete overview of Alan Hovhaness’s collective saxophone music, including detailed information about each piece’s historical and cultural significance. Hovhaness composed eleven pieces for the saxophone and chamber ensemble. Since many were not published until later in his life, there is minimal scholarly writing about them. The pieces were composed over two periods of Hovhaness’s life, 1949 to 1954 and 1976 and 1984. His saxophone music from both eras is analyzed, and the details of each composition in relation to his career and personal life are discussed. Additionally, how these pieces were received by the …

Exth-52. Simultaneous Targeting Of Tumor Cells And Tumor-Associated Macrophages To Reprogram Glioblastoma By Tumor-Suppressive Microrna, Grace Nguyen, Minhye Noh, Alexandra Miller, Minxin Huang, Yulin Dai, Zhongming Zhao, Ji Young Yoo, Tae Jin Lee

Faculty, Staff and Student Publications

Glioblastoma (GBM) is the most aggressive type of primary brain tumors due in part to cell-intrinsic and cell-extrinsic mechanisms. The ability of GBM tumor to not only resist conventional therapies but also induce an immunosuppressive tumor microenvironment (TME) is thought to underlie the failure of immunotherapies. Thus, strategies to target both tumor cells and immunosuppressive immune cells, such as tumor-associated macrophages (TAMs), are of great interest. The ability of microRNA (miRNA) to target multiple genes is favorable to alter the character of the TME and cancer cells. Previously, we have shown that tumor suppressive miRNA, miR-138, can effectively regulate the …

The Echo: November 11, 2024, Taylor University

2024-2025 (Volume 112)

No abstract provided.

Impact Of Coverage And Guest Residue On Polyproline Ii Helix Peptide Antifouling, Rebecca S. Ahn, Henry T. Grome, Sogol Asaei, Geeta Verma, Christina S. Dang, Harihara Baskaran, Julie N. Renner

Faculty Scholarship

Polyproline II (PPII) peptide sequences are recognized as promising biomaterials because of their attractive antifouling properties. However, the mechanisms behind their antifouling behavior have not been fully characterized. In this work we show that PPII peptide coverage, controlled by adsorption time, significantly reduces the fouling of bovine serum albumin (BSA, a model foulant). In addition, guest residues introduced into the PPII sequence are shown to significantly impact BSA adsorption as well as human mesenchymal stem cell (hMSC) spreading. This research will help guide future PPII peptide designs for incorporation into novel biomaterials.

Revealing Students’ Career Interests From Textual Responses: An Application Of Structural Topic Model, Yuxiao Zhang, Tugce Karatas, Nielsen Pereira, Sarah Bright, Hua-Hua Chang

Purdue AI in P-12 Education Conference

This study utilizes the Structural Topic Model (STM; Roberts et al., 2014) to uncover key career interests among secondary school students from their open-ended survey responses. Textual data from students were analyzed to identify five core career interest themes, and covariate analysis revealed gender differences and associations between giftedness scores and career interests. These findings demonstrate the potential of STM as a robust tool for analyzing large-scale textual data, enabling educators to tailor career guidance programs.

Differences Between The Reintegration Of Combat Veterans And Noncombat Veterans While Controlling For Stigma, Caroline Ramos

Walden Dissertations and Doctoral Studies

Veterans face challenges in reintegrating into civilian life. Experiences of public stigma arise from socially learned stereotypes about military service and mental health issues, which can impact veterans' ability to reintegrate following military deployment successfully. Goffman’s theory of stigma details its influences on personal adjustment. The purpose of this quantitative research study utilizing a survey design was to assess the role of public stigma as a mediator between the type of deployment and veterans’ reintegration experiences. A snowball sample of 85 recently discharged veteran volunteers representing combat zone deployed or non-combat zone deployed completed the Military Stigma Scale and the …

Childhood Trauma As An Influencing Factor On Obesity Among Black Women, Andréa Autum Michel

Walden Dissertations and Doctoral Studies

Childhood trauma and obesity have a significant impact on development throughout the lifespan. Black women have the highest prevalence of obesity and experience more severe and a greater number of traumatic events than their White peers. The purpose of this phenomenological study was to explore how Black women perceived the role of childhood trauma in their struggles with obesity. Bronfenbrenner’s ecological systems theory served as the theoretical framework for this study. The central research question explored the experiences of Black women who experienced childhood trauma and were struggling with obesity as adults. A secondary question explored coping mechanisms developed to …

Examining Ptsd Prevalence Among Underserved Populations In The Integrated Community Mental Health Setting 2019 To 2022, Siran Koroukian, Stephen Zyzanski, Kurt C. Stange

Faculty Scholarship

Background: The prevalence of Post Traumatic Stress Disorder (PTSD) has been rising since the start of the COVID-19 pandemic, and affects females, sexual and gender minorities, and individuals with social risks at higher rates. Objective: This study examines if the prevalence of PTSD increased from 2019 to 2022 among patients who received care in a national network of safety-net, community-based health centers with integrated behavioral health programs that serve patients at high risk for PTSD. Methods: We analyzed electronic health record data from patients with 1 or more behavioral health visits during 2019 to 2022 using repeated cross-sectional data to …

Kemampuan Berpikir Kreatif Dan Pemahaman Konsep Matematis Siswa Di Indonesia: Analisis Jalur Dengan Structural Equation Model, Komarudin Komarudin, Achi Rinaldi, Rikka Yulina, Suherman Suherman, Laila Puspita

PYTHAGORAS : Jurnal Matematika dan Pendidikan Matematika

This study analyzes the relationship between creative thinking ability and understanding of mathematical concepts. The data were taken from 58 respondents who came from class XI students of SMA Negeri in Bandar Lampung. The data analysis used was path analysis, in order to see direct and indirect relationships between latent variables and to reconfirm the hypothesized model with the help of SPSS and Lisrel 8.80. The results showed that there was a good relationship between latent variables and other latent variables and between indicator variables and the latent variables themselves. There is a linear combination of the five latent variables …

Analisa Kestabilan Bebas Kecanduan Pada Penyebaran Penggunaan Media Sosial Berdasarkan Model Searqs, Ratna Widayati, Intrada Reviladi

PYTHAGORAS : Jurnal Matematika dan Pendidikan Matematika

In this paper we discussed about the model of social media addiction and stability analysis of the equilibrium point as well as its numerical simulation by assuming the individual population is divided into 5 classes, namely Susceptible individual, Expose individuals, Addicted individuals, Recover individuals. The SEARQS model is used. The assumptios used are no deaths due to social media addiction. In addition, individuals who have quit social media addiction may return to being Susceptible individuals. The problem that arises from the spread of excessive use of social media is how to know when individuals who are addicted to social media …

Pengembangan Media Play Mathematics With Technology Dalam Melatihkan Berpikir Kritis Dan Pemecahan Masalah Siswa, Siti Lailiyah, Kusaeri Kusaeri, Anni Mujahidad Dina, Elmita Irmanila, Putri Dwi Nuryaningsih

PYTHAGORAS : Jurnal Matematika dan Pendidikan Matematika

21st century education must facilitate distance learning, and students are required to have critical thinking and problem-solving skills. Therefore, it is important to develop technology-based mathematics learning media in practicing critical thinking and problem-solving skills. This type of research is development research with a quantitative approach. The development phase consists of 6 phases: initiation, specification, design, production, review and evaluation, delivery and implementation. The selection of research subjects were 36 students of class V, 27 students of class IX, and 30 students of class XII. The research instruments are observation sheets, interviews, response questionnaires, and critical thinking and problem-solving tests. …

Leveraging Quantitative Systems Pharmacology For Dose Optimization In Oncology Drug Development, Blerta Shtylla

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Examining Adolescence And Agency In The Midst Of International Crisis: Pandemics, Pandemonium, And Zombie Young Adult Literature, T. Hunter Strickland

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

The COVID-19 pandemic of 2020-22 brought an abundance of changes to secondary education as students transitioned across the country to virtual and hybrid learning contexts. Teachers flexed quickly and frequently to support the learning that students acquired in these new, digital spaces even as school, district, and state demands on teaching increased. The English/Language Arts classroom pivoted along with others as teachers sought out digital reading and writing resources for students to engage in. In the midst of a national crisis, a metaphorical monster that sought to destroy, much like Beowulf ’s dragon did, adolescent readers, despite the discourses of …

Biomechanical Insights Of Head Trauma Based On Computational Simulation, Ghaidaa Abdulrahman Khalid

AUIQ Technical Engineering Science

Head injuries from falls are a major cause of illness and death in children due to trauma. Despite their prevalence and impact, there is limited understanding of how children's heads react during impact events. Infant Post-Mortem-Human-Surrogate (PMHS) testing, a reasonable method for studying impact biomechanics, faces significant restrictions due to emotional, moral, and ethical issues. Computer modeling, though holding significant promise for creating alternative pediatric head surrogates, encounters numerous challenges because of the intricacies of child growth and development. A finite-element (FE) model of an infant head was created from high-resolution CT scans, utilizing published data on tissue material properties. …

Large Dams Establishment Impacts On Different Environmental Aspects: A Review, Anas Ahmad

AUIQ Technical Engineering Science

The construction of large dams has been an essential component of the development of global infrastructure, offering significant advantages such as ensuring water storage, reducing the risk of flooding, and producing about 20% of the world's electricity through hydropower. On the other hand, these structures have significant and varied environmental effects. The environmental effects of large dams are critically examined in this analysis, with an emphasis on four main areas: fish biodiversity, riparian vegetation, sediment deposition, and water quality. The study estimates the degree of these consequences by examining global case studies and evaluating data from over 145 significant rivers …

Mixedness Comes Of Age: Learning From Multiracial Portrayals In Young Adult Tv Series, Marc P. Johnston-Guerrero, Lisa Delacruz Combs

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Representation in literature, popular culture, and media has been shown to influence identity development and belonging as exemplified in the enduring hashtag #RepresentationMatters. However, mixed race representation on television has received little attention in research and scholarship. Hence, this essay examines how multiracial characters are portrayed in coming of age and young adult storylines from four TV series (All American, Charmed, Trinkets, and Dear White Peoples) representing two different networks (Netflix and The CW). Through a close reading of dialogue within the context of larger story arcs, we identify and critique common tropes in order …

Synthesis And Evaluation Of Cyclic Peptide-Dasatinib Conjugates As Anti-Melanoma Agents, Shaban Darwish, Dorna Davani-Davari, Shirley Tong, Rakesh Kumar Tiwari, Sun Yang, Keykavous Parang

Pharmacy Faculty Articles and Research

Herein, we synthesized two amphiphilic cyclic peptides, incorporating tryptophan and arginine residues, linked to dasatinib via a Cathepsin B-sensitive tetrapeptide (Gly-Phe-Leu-Gly). To mitigate steric hindrance and optimize drug release, we integrated two different linkers, succinate and glutarate, between the drug and peptide. The synthesis involved solid-phase techniques for the assembly of the peptide, followed by the coupling of the peptide on-resin with the linker, mild cleavage, and solution-phase cyclization. Conjugation of the peptide-attached linker with dasatinib was conducted in the presence of N-methylmorpholine and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC), generating the novel prodrugs. The synthesized compounds were characterized by high-resolution mass …

Myc And Egr1 Expression In Colorectal Cancer Cells With An Oncogenic Mutation In Ctnnb1 And Normal P53, Sophia Vickers, Erick Spears, Phd

Science University Research Symposium (SURS)

Cancer is often initiated by genetic alterations that affect cellular proliferation, survival, and differentiation. Colorectal cancers are specifically initiated and driven by mutations affecting the Wnt signaling pathway and mutations in the CTNNB1 gene are the second most common of these mutations found in colorectal cancers. Among these, mutations in the CTNNB1 gene, encoding β-catenin, frequently lead to dysregulated Wnt signaling, a hallmark of colorectal cancer. The proto-oncogene MYC and the early growth response gene EGR1 are known to be critical downstream effectors of several oncogenic pathways. MYC is a known β-catenin target gene and under certain cellular contexts, EGR1 …

Teaching With Pedagogy And Empathy, Mamoona Muzammil, Muzammil Arshad, Washain Muzammil

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Mental illness is common and can affect anyone. Each year the University welcomes students with Mental Health Issues. One in four adults in the US will experience a mental illness in their lifetime, however according to a NUS survey, eight out of ten students will experience a mental illness while in higher education. For some student’s mental illness can be a lifelong disability. Others can experience short term issues that emerge around difficult or stressful life events, while some students may be more at risk of experiencing mental illness in relation to their ethnicity, gender, sexuality or socio-economic background. Although …

Addition Of Metastasis-Directed Therapy To Systemic Therapy For Oligometastatic Pancreatic Ductal Adenocarcinoma (Extend): A Multicenter, Randomized Phase Ii Trial, Ethan B Ludmir, Alexander D Sherry, Bryan M Fellman, Suyu Liu, Tharakeswara Bathala, Cara Haymaker, Marina N Medina-Rosales, Alexandre Reuben, Emma B Holliday, Grace L Smith, Sonal S Noticewala, Sarah Nicholas, Tracy R Price, Rachael M Martin-Paulpeter, Luis A Perles, Sunyoung S Lee, Michael S Lee, Brandon G Smaglo, Ryan W Huey, Jason Willis, Dan Zhao, Lorenzo Cohen, Cullen M Taniguchi, Eugene J Koay, Matthew H G Katz, Robert A Wolff, Prajnan Das, Shubham Pant, Albert C Koong, Chad Tang

Faculty, Staff and Student Publications

Purpose: The EXTEND trial tested the hypothesis that adding comprehensive metastasis-directed therapy (MDT) to chemotherapy would improve progression-free survival (PFS) over chemotherapy alone among patients with oligometastatic pancreatic ductal adenocarcinoma (PDAC).

Methods: EXTEND (ClinicalTrials.gov identifier: NCT03599765) is a multicenter, phase II basket trial randomly assigning patients with ≤five metastases 1:1 to MDT plus systemic therapy versus systemic therapy. Disease progression was defined by radiologic criteria (RECIST v1.1), clinical progression, or death. The primary end point was PFS in the per-protocol population, evaluated after all patients achieved at least 6 months of follow-up. Exploratory end points included systemic immune response …

Dna Methylation Classifier To Diagnose Pancreatic Ductal Adenocarcinoma Metastases From Different Anatomical Sites, Teodor G Calina, Eilís Perez, Elena Grafenhorst, Jamal Benhamida, Simon Schallenberg, Adrian Popescu, Ines Koch, Tobias Janik, Baoqing Chen, Jana Ihlow, Stephanie Roessler, Benjamin Goeppert, Bruno Sinn, Marcus Bahra, George A Calin, Eliane T Taube, Uwe Pelzer, Christopher C M Neumann, David Horst, Erik Knutsen, David Capper, Mihnea P Dragomir

Faculty, Staff and Student Publications

Background: We have recently constructed a DNA methylation classifier that can discriminate between pancreatic ductal adenocarcinoma (PAAD) liver metastasis and intrahepatic cholangiocarcinoma (iCCA) with high accuracy (PAAD-iCCA-Classifier). PAAD is one of the leading causes of cancer of unknown primary and diagnosis is based on exclusion of other malignancies. Therefore, our focus was to investigate whether the PAAD-iCCA-Classifier can be used to diagnose PAAD metastases from other sites.

Methods: For this scope, the anomaly detection filter of the initial classifier was expanded by 8 additional mimicker carcinomas, amounting to a total of 10 carcinomas in the negative class. We validated the …

Efficient Correction Of Dna Hetero–Duplexes Formed During Selex Procedure, Adil Sabr Al-Ogaili, Billy Hargis, Young Min Kwan

Poultry Science Faculty Publications and Presentations

Background:Aptamers, oligos-based (ssDNA or RNA) and peptide-based, are now emerging as the first-choice biomolecules in various applications in medicine and biology. DNA aptamers selection process includes repeatable steps of DNA amplification and digestion. The amplification process of the enriched DNA aptamers includes using PCR. Objectiveof study:In this article, we sought to describe an efficient and robust method that corrects or permanently removes the PCR by–products during the cycles of DNA aptamers selection. Materialsand Methods:Our method is simple, efficient, and requires no enzymatic treatment. In this method, we applied repetitive cycles of thermal treatment to the enriched aptamers final products during …

Embracing The Fiasco!: Roleplaying Games, Pedagogy And Student Success, Erik Stanley, Michelle Schmidt, David Sweeten

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

This article explores the relationship between games and pedagogy through the example of the roleplaying game Fiasco!. Fiasco! is a part of a growing genre of collaborative roleplaying games (RPGs) that have important applications in the university classroom. Fiasco! is an innovative game system that upends the traditional model of Game Master-led RPGs to create a collaborative environment for players to create their own stories. This paper explores how the unique model embedded within Fiasco! can be employed as a pedagogical tool for active student-led learning.

To showcase the pedagogical innovations of a game like Fiasco!, we present …

Critique And “Controversy” In Pedagogy And Pop Culture [Dialogue: The Interdisciplinary Journal Of Popular Culture And Pedagogy, Volume 9, Issue 3 (August 2022)], Miriam Sciala

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Critique and “Controversy” in Pedagogy and Pop Culture [Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy, Volume 9, Issue 3 (August 2022)]

Editorial

Teaching for Change, Miriam Sciala

Articles

Peril and Promise: Student Experiences of Virtual Reality and Implications for Inclusive Social Justice Pedagogy, Michelle VanNatta

Will the Odds Ever Be in Her Favor? Katniss Everdeen and the Female Athlete, Tony Kemerly

Don’t Sweat the Technique: Rhetoric, Coded Social Critique, and Conspiracy Theories in Hip-Hop, Josh Chase

Cake and Conclusions: Rhetorical Roots in “Sheetcaking” and Fallacious Community Responses, Marissa Lammon

Musings (Online Only)

Teaching and Learning Popular Media Cultures: …