Digital Commons Network^™

Wolves Across Borders, Ilse Storch, Aimee Tallian, Luigi Boitani, Cecilia Di Bernardi, Josip Kusak, Çağan Şekercioğlu, Douglas Smith, John Vucetich, Barbara Zimmermann

Michigan Tech Publications

No abstract provided.

Prone Positioning Is Associated With Increased Insulin Requirements In Mechanically Ventilated Patients With Covid-19, Harry Griffiths, Amy Cardwell, Max Richardson, Meg Barne, Bogdan Petrisor, Ammara Usman, Laura Heales, Julia Calvo Latorre, Vishakha Bansiya, Razeen Mahroof, Tamas Szakmany, Daniel Martin, Anthony Rostron, Andrew Conway Morris, Sam Lockhart

Peninsula Medical School

Stress hyperglycaemia is common in critical illness. We have previously observed that increasing severity of respiratory failure in patients with severe COVID-19 is associated with increased insulin demand. Given previously reported direct effects of hypoxia on insulin action, we reasoned that rapid improvements in oxygenation following prone positioning may improve insulin sensitivity and increase risk of hypoglycaemia. A retrospective multi-centre service evaluation comparing blood glucose and insulin administration in patients with COVID-19 pneumonitis receiving prone mechanical ventilation, comparing the 16 h pre-prone and 16 h post-prone time periods. 155 patients were included in this analysis. Oxygenation improved significantly following prone …

Identification And Characterization Of The Lipoprotein N-Acyltransferase In Bacteroides, Krista M Armbruster, Jiawen Jiang, Mariana G Sartorio, Nichollas E Scott, Jenna M Peterson, Jonathan Z Sexton, Mario F Feldman, Nicole M Koropatkin

2020-Current year OA Pubs

Members of the Bacteroidota compose a large portion of the human gut microbiota, contributing to overall gut health via the degradation of various polysaccharides. This process is facilitated by lipoproteins, globular proteins anchored to the cell surface by a lipidated N-terminal cysteine. Despite their importance, lipoprotein synthesis by these bacteria is understudied. In

Dilated Cardiomyopathy-Associated Skeletal Muscle Actin (Acta1) Mutation R256h Disrupts Actin Structure And Function And Causes Cardiomyocyte Hypocontractility, Ankit Garg, Silvia Jansen, Lina Greenberg, Rui Zhang, Kory J Lavine, Michael J Greenberg

2020-Current year OA Pubs

Skeletal muscle actin (ACTA1) mutations are a prevalent cause of skeletal myopathies consistent with ACTA1's high expression in skeletal muscle. Rare de novo mutations in ACTA1 associated with combined cardiac and skeletal myopathies have been reported, but ACTA1 represents only ~20% of the total actin pool in cardiomyocytes, making its role in cardiomyopathy controversial. Here we demonstrate how a mutation in an actin isoform expressed at low levels in cardiomyocytes can cause cardiomyopathy by focusing on a unique ACTA1 variant, R256H. We previously identified this variant in a family with dilated cardiomyopathy, who had reduced systolic function without clinical skeletal …

A Contemporary Review Of Robotic Resection For Hepatocellular Carcinoma, William A. Preston, Nina R. Spitofsky, Adam S. Bodzin

Department of Surgery Faculty Papers

Background: Robotic hepatectomy represents an appealing treatment modality for resectable hepatocellular carcinoma (HCC). A contemporary review of robotic hepatectomy compared to laparo- scopic/open hepatectomy is necessary. Methods: We performed a literature review to identify studies between 2018–2024 comparing robotic to laparoscopic/open hepatectomy for HCC with measurable outcomes. Results: A total of 10 studies were identified, including 943 patients undergoing robotic hepatectomy compared to 1678 patients undergoing laparoscopic/open hepatectomy. Generally, while similar short/long-term survival was noted across all resection modalities, robotic hepatectomy was associated with longer operative time, shorter length of stay, and less post-operative compli- cations. An additional 4 studies …

Things Fall(Ing) Apart: Deconstructing Humanism For History Teaching In A Posthumanist Society, Lou Ellis Brassington

Language, Literacy, and Sociocultural Studies ETDs

Abstract

This study is a reflective analysis of the discursive construction of the social studies and the teaching of history from medieval scholasticism, through Enlightenment humanism, and into our posthumanist landscape. As an exploration of the foundations of Western thought, with an emphasis on humanism as it has historically affected construction of the social studies, this investigation focuses on theorists, praxis, curriculum development, and teacher identity. My research examined the pedagogical and curriculum choices for the teaching of history along with the intersection of the humanities and humanism from the Enlightenment through the criticalities of the 20th century, and into …

Investigating Secondary Metabolites Of Streptomyces And Bacillus Bacteria That Inhibit Colony Growth Of Pathogenic Potato Fungi (Colletotrichum Coccodes, Pythium Ultimum), Jacob R. Henrie

Theses and Dissertations

Potato (Solanum tuberosum) is a crucial global food crop, yet its production is threatened by fungal pathogens such as Pythium ultimum and Colletotrichum coccodes, which cause significant yield losses and impact tuber quality. In this study, we investigated the antifungal properties of various Streptomyces and Bacillus isolates against these pathogens. The Streptomyces isolates, known for their prolific secondary metabolite production, were selected for their varying efficacy against these fungi. Despite the anticipated potential, Streptomyces isolates exhibited limited antifungal activity against Pythium ultimum and only moderate activity against Colletotrichum coccodes. In contrast, Bacillus isolates, particularly B1, demonstrated strong inhibition of C. …

Genetic Associations Of Il-2 (Rs2069762) And Egr3 (Rs3750192) Polymorphisms With Schizophrenia: A Meta-Analysis, Anu Shibi Anilkumar, Sheena Mariam Thomas, Ramakrishnan Veerabathiran

Folia Medica Indonesiana

Highlights:
1.The novelty of this study lies in its thorough examination of gene polymorphisms and their associations with schizophrenia risk across different populations.
2.This meta-analysis provides new insights by highlighting the lack of reliable association for interleukin-2 (IL-2) rs2069762 and revealing a substantial protective effect of early growth response 3 (EGR3) rs3750192 in specific ethnic groups, particularly among Polish and Chinese.

Abstract
Although genome-wide association studies have identified numerous genes linked to schizophrenia, their specific roles remain unclear. This meta-analysis sought to explore the association of polymorphisms in the interleukin-2 (IL-2) rs2069762 and early growth response 3 (EGR3) rs3750192 with …

From "Open Ocean" To "Exposed Aquaculture": Why And How We Are Changing The Standard Terminology Describing "Offshore Aquaculture", Tyler Sclodnick, Michael Chambers, Barry Antonio Costa-Pierce, Tobias Dewhurst, Nils Goseberg, Kevin Gerald Heasman, Wolf Isbert, Gesche Krause, Daniel Wieczorek, Till Markus, Bela H. Buck

Faculty Publications

The term “offshore” with regards to aquaculture has hitherto encompassed various perspectives, including technology, geographic location, legal jurisdiction, and more. To resolve the ambiguity in this term and understand its implications for current and future aquaculture development, “offshore” should be resolved into two separate metrics: distance from shore and energy exposure. The United Nations Convention on the Law of the Sea (UNCLOS) distinguishes between internal waters, territorial sea, contiguous zone, exclusive economic zone (EEZ), and the high seas, but currently has no precise definition for “offshore” in its provisions, and therefore no applicable laws pertaining to “offshore” aquaculture. Regulating a …

Evaluating The Impact Of Semiglutide On Weight Loss In Overweight Adults, Justina 0. Umweni-Oyiboke

Walden Dissertations and Doctoral Studies

Obesity is a pressing health issue. By 2030, it is estimated that nearly half of all adults in the United States will be obese. This trend has serious consequences for both physical and mental health. Obese individuals face an increased risk of conditions like cardiovascular disease, type 2 diabetes, fatty liver disease, osteoarthritis, and even depression. In this Doctor of Nursing Practice Project, I evaluated the effectiveness of a quality improvement (QI) initiative at the project site that addressed the practice problem of inadequate weight loss management caused by relying solely on diet and exercise as treatment strategies. The QI …

Concealed Cognitive Disabilities, Bullying In The Workplace, And The Americans With Disabilities Act, Craig Darrell Taylor

Walden Dissertations and Doctoral Studies

This qualitative study uniquely explores the perceptions of individuals with concealable cognitive disabilities (CCDs) regarding Titles I–III of the Americans with Disabilities Act and its amendments (ADAAA). The research addresses a significant gap in understanding this population’s views on workplace experiences, particularly in the context of harassment, privacy, self-identification, and labeling. Using Schneider and Ingram’s social construction framework to examine societal power dynamics, the study analyzed interviews with eight participants, employing rigorous thematic coding. The analysis revealed four key themes: social construction (perception in the workplace and the power of employment protections), disability (cognitive disabilities and the challenges of disclosure …

Association Between Adults’ Perceptions Of Their Parents’ Parenting Behaviors During Youth And Resulting Attachment Dimensions In Adulthood In The Native American Community, Christine Marie Summering

Walden Dissertations and Doctoral Studies

Forced assimilation of Native American peoples has led to the destruction of their traditional ways of life and contributed to heightened rates of Native American children in foster care, increased domestic violence, substance abuse, alcoholism, and poverty. The purpose of this study was to understand associations between perceived parenting behaviors and current adult attachment within Native American communities and whether those associations were moderated by historical loss. The attachment theory and historical trauma theory were used as theoretical foundations for the study. Research questions for this nonexperimental quantitative study involved associations between warmth and involvement and anxious and avoidant attachment …

Concealed Cognitive Disabilities, Bullying In The Workplace, And The Americans With Disabilities Act, Craig Darrell Taylor

Walden Dissertations and Doctoral Studies

This qualitative study uniquely explores the perceptions of individuals with concealable cognitive disabilities (CCDs) regarding Titles I–III of the Americans with Disabilities Act and its amendments (ADAAA). The research addresses a significant gap in understanding this population’s views on workplace experiences, particularly in the context of harassment, privacy, self-identification, and labeling. Using Schneider and Ingram’s social construction framework to examine societal power dynamics, the study analyzed interviews with eight participants, employing rigorous thematic coding. The analysis revealed four key themes: social construction (perception in the workplace and the power of employment protections), disability (cognitive disabilities and the challenges of disclosure …

Crosslinked Colloidal Cellulose Nanocrystals And Methods Of Preparation And Use Thereof, Jin-Woo Kim, Joseph N. Batta-Mpouma, Joshua Sakon

Patents Granted

This invention relates generally to covalently crosslinked colloidal cellulose nanocrystals (xCNC) and methods of preparation and use thereof. The colloidal cellulose nanocrystals (CNCs) are covalently crosslinked in aqueous suspension to generate a network showing tunable physicochemical properties. The xCNC structures are tunable in terms of their physicochemical properties and arrangement within the hydrogel network. The covalent crosslinking of solitary sulfonated (—OSO.sub.3) CNCs can be accomplished without prior hydroxyl replacement or functionalization.

Clarifying Ethical Dilemmas Of Using Artificial Intelligence In Research Writing: A Rapid Review, Ndubuisi Friday Ugwu Phd, Adewumi Segun Igbinlade Phd, Raphael E. Ochiaka Phd, Ugoma Deborah Ezeani Phd, Nnaemeka Chijioke Okorie Mr, Jacob Kehinde Opele Phd, Toyin Segun Onayinka Phd, Obinna Iroegbu Phd, Ogechi Kate Onyekwere Phd, Adijat Bolanle Adams Dr, Precious Aigbona Ms, Folasade Busayo Ojobola Phd

Higher Learning Research Communications

Objective: The purpose of the study was to clarify, through the lenses of experts and frontline publishers, ethical dilemmas related to the use of artificial intelligence (AI) in research writing.

Method: We conducted a rapid review of expert opinions and publishers’ policy statements on ethical considerations in using AI for research writing. We included articles published in journals indexed by academic databases that met the criteria. We also included the policy statements and guidelines of seven reputable publishers.

Result: The use of AI in scientific writing is acceptable, contingent on addressing ethical considerations bordering on plagiarism, transparency, and disclosure. While …

What Motivates The Choice To Custom Hire Pest Management Spraying Services?, Braeden Van Deye, Trey Malone

Department of Agricultural Economics Faculty Publications

BACKGROUND

This article presents a model of how farmers choose to custom hire for pest control. The decision-making process is illustrated through a discrete choice experiment conducted via a pilot survey of soybean growers in Michigan, Illinois, and Indiana. Farmers responded to a hypothetical pest infestation by choosing between custom operators, spraying on their own, or leaving the field to its fate.

RESULTS

Among farmers who choose to spray, the mean willingness to pay for marginal increases in timeliness (as defined as the chance of late spraying) ranges from 37 to 52 cents per acre. We also find that farmers …

Hypnopressure As A Non-Invasive Method For Anxiety And Pain Management In Primigravidae During Active Labor, Yeni Fitrianingsih, Hanung Prasetya, Rani Widiyanti

Folia Medica Indonesiana

Highlights:
1. This study applied hypnopressure, an innovative method that combines auditory hypnosis with acupressure on effective uterine points, namely the Hegu (LI4) and Sanyinjiao (Sp6) points.
2. This innovation offers an effective method for managing labor pain in primigravidae during the active phase of the first labor stage compared to hypnotherapy and acupressure administered separately.

Abstract
Psychological factors, such as fear and anxiety, are often responsible for prolonged labor. Anxiety affects 58% of primigravidae, while 2–4% experience pain with scores ranging from 30 to 40 out of 50. Hypnopressure is an innovative combination of hypnotherapy and acupressure applied on …

Prognostic Nutritional Index With Wound Complication After Laparotomy In Colorectal Cancer Patients At Dr. Zainoel Abidin General Hospital Banda Aceh, Amirul Hadi, Muhammad Yusuf, Iflan Naufal, Imam Hidayat

Folia Medica Indonesiana

Colorectal cancer patients generally undergo laparotomy as part of the management. The earliest complications of laparotomy are bleeding, surgical wound infection, and anastomotic dehiscence. Albumin-lymphocytes are indicators of nutritional status and inflammation combined in the Prognostic Nutritional Index (PNI). Evaluation of PNI related to the degree of post-laparotomy wounds in colorectal cancer has not been widely explained. Objective: to find out the correlation of PNI for laparotomy wound complications in colorectal cancer patients at Dr. Zainoel Abidin General Hospital Banda Aceh. Method: A cross-sectional study will assess the correlation of PNI to the degree of post-operative wounds with the South …

Urine Periostin Level And Renal Function In Malignancy Patients Treated With High-Dose Cisplatine, Harry Yusuf, Andhika Rachman, M Bonar Marbun, Hamzah Shatri, Putri Aliya Ahadini

Folia Medica Indonesiana

Cisplatin has been used extensively as a cancer treatment. Nephrotoxicity, which is assessed by blood urea levels, blood creatinine, and estimated glomerular filtration rate (eGFR), is caused by cisplatin metabolites that build up in the kidneys. Because of these indicators' numerous flaws, optimal biological markers are required. One of the key mediators of inflammatory processes, such as kidney fibrosis and inflammation, is periostin. In cancer patients undergoing high-dose cisplatin therapy, the purpose of this study is to ascertain how urine periostin changes and how it relates to kidney function. This cross-sectional study was carried out at the National Center General …

The Tubarial Glands: Key Anatomical Features And Clinical Significance, Dwi Martha Nur Aditya, Winnie Nirmala Santosa, Jefman Efendi Marzuki, Devitya Angielevi Sukarno, Baharuddin Baharuddin, Dita Sukmaya Prawitasari, Sajuni Sajuni, Adhimas Setyo Wicaksono, Stephanie Natasha Djuanda

Folia Medica Indonesiana

Medical technological advancements have revealed previously unknown anatomical features in the nasal cavity known as tubarial glands. However, many questions remain unanswered concerning these glands. Through this systematic review, we sought to analyze the tubarial glands, including their major discovery, anatomical and histological features, and clinical significance. Articles were identified according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, with data collected from Scopus, ScienceDirect, SpringerLink, and PubMed until September 2024. Medical Subject Headings (MeSH) were utilized with various terminology: "tubarial gland*", "tubarial salivary gland*", and "radiotherapy”. The inclusion criteria were: (1) resources categorized as original …

Associations Between Dietary Patterns And Quality Of Life In A Longitudinal Cohort Of Colorectal Cancer Survivors, Kristen S Smith, Adetunji T Toriola, Et Al.

2020-Current year OA Pubs

PURPOSE: To characterize dietary patterns and examine associations with cross-sectional and longitudinal changes in quality of life (QOL) over approximately one year after colorectal cancer (CRC) diagnosis.

METHODS: The ColoCare Study is an international, multi-center, prospective cohort study of newly diagnosed CRC survivors of any stage. A subset of participants with CRC in the United States completed patient-reported outcome measures at 6- and 12-months post-enrollment, including the Food Frequency Questionnaire (FFQ) and European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). Dietary patterns at 6 months (around the time of treatment completion) were identified …

Complete Genome Sequence Of Borrelia Miyamotoi Strain Mn18-0001, An Am-East-2 Strain Type Isolate Derived From An Ixodes Scapularis Tick (Minnesota), Alexander R Kneubehl, Lynn M Osikowicz, Christina M Parise, Taylor J Van Gundy, Adam J Replogle, Job E Lopez, Rebecca J Eisen, Andrias Hojgaard

Faculty, Staff and Students Publications

We report the genomic sequence of the hard tick relapsing fever spirochete Borrelia miyamotoi strain MN18-0001. B. miyamotoi causes human illness and is geographically widespread in Ixodes spp. (Acari: Ixodidae) ticks. This is a chromosome- and plasmid-resolved genome assembly of an Am-East-2 strain type isolate from the midwestern United States.

Experiments In Love: Longus’ Daphnis & Chloe And Henry De Vere Stacpoole’S The Blue Lagoon, L. Kirsten Day

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Despite a chronological gulf of nearly two thousand years, the second century C. E. Greek romance writer Longus and the early twentieth century Irish novelist Henry de Vere Stacpoole were prompted to produce their best works by a similar motive: an urge to explore the world, and particularly the phenomenon of love and desire, from a standpoint of complete innocence. Although the resulting novels, Daphnis & Chloe and The Blue Lagoon respectively, have no evident direct connection, they exhibit surprising similarities not only in plot, setting, and characterization, but also in the values, perspectives, and worldviews they advance. The striking …

Vol. 38, No. 8 - Whole No. 233, Eleanor M. Farrell

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Engaging Students With Pocketlab Interactive Mobile Technology In A Science Classroom: A Mixed Methods Study, Olha Ketsman, Juan A. Colon Santana

Mid-Western Educational Researcher

This mixed methods study explored the impact of PocketLab interactive mobile sensors on science content knowledge among undergraduate students in an algebra-based physics laboratory course. The study also examined students' perspectives and experiences using PocketLab to learn class concepts. While no statistically significant differences were found between the control and treatment groups for items evaluating definitions and conceptual mastery, the control group outperformed the treatment group on problem-solving items. This difference may be due to the alignment of traditional Vernier technology experiments with the analytical problem-solving approach emphasized in lectures. Despite this, students using PocketLab reported greater flexibility and …

The Effect Of Nerolidol On The Renal Dysfunction Following Bilateral Ureteral Obstruction In The Rat, Harun Rashed Toumi

Thesis/ Dissertation Defenses

This thesis addressed nerolidol’s potential therapeutic and protective effects on bilateral ureteral obstruction-induced uropathy in rats. Obstructive uropathy stands as a notable contributor to acute kidney injury (AKI), accounting for 5-10% of all AKI cases worldwide, with a particularly high prevalence among the elderly, constituting 22% of AKI cases in this age group. Urinary tract obstruction, often attributed to factors such as kidney stones, urinary tract deformities and benign/malignant growths such as benign prostatic hyperplasia (BPH) in older men can lead to detrimental outcomes if left untreated, potentially progressing to kidney failure and even mortality. The severity of the kidney …

Scholar Perspectives On The Impact Of A Scientific Community Program For Neurodivergent Undergraduate Stem Scholars, Dylan Sullivan, Fernando Zavala, Derek Hidalgo, Jacob Stolle, Rebecca Matte, Christin B. Monroe

Journal of Science Education for Students with Disabilities

Despite the adaptive strengths and unique problem-solving skills demonstrated by neurodivergent (ND) individuals, they remain underrepresented in Science, Technology, Engineering and Mathematics (STEM) fields. High unemployment rates among individuals with disabilities emphasize the need for addressing barriers to entry and persistence in the workforce. This study introduces a program designed to enhance opportunities for neurodivergent STEM scholars with financial needs, supported by the National Science Foundation (NSF). The program involves: 1) a weekly cohort course to engage in professional development, 2) use of the Birkman Method® survey to help scholars identify and communicate strengths, fostering self-awareness and growth, and 3) …

Tityopsis Rolandoi Sp. N. (Scorpiones: Buthidae) From Cuba, František Kovařík, Mark Stockmann, František Šťáhlavský, Sheyla Yong

Euscorpius

A new species Tityopsis rolandoi sp. n. is described from Cuba, fully illustrated with color photos showing its morphology and habitus. T. rolandoi sp. n. is the only species of the genus with a combination of two characters: movable finger shorter than carapace and chela length/width ratio 3.6 in male. This species also has a characteristic shape of a median smooth patch of sternite V, which is almost oval in male. In addition to morphology, we present the information about the karyotype of T. rolandoi sp. n. (2n=20) and T. sheylae (2n=22).

Todaro Channeled Apple Snail (Pomacea Canaliculata), Jasmyn Todaro, Amy C. Hirons

Hirons Field Techniques

Channeled Apple Snail (Pomacea canaliculata) shell.

The Effects Of Sunlight On The Decomposition Rate Of Opuntia Humifusa, Paul George, Elena Amonette, Celine W. Seder, Katherine Massaro

Science University Research Symposium (SURS)

Plant decomposition plays a critical role in community and ecosystem ecology by recycling minerals and returning nutrients to the soil. The rate of plant decomposition can be impacted by a multitude of factors including chemical composition of the plant, presence of decomposing microorganisms, temperature, and more. This study sought to quantify the effects of sunlight on plant decomposition. In this project, Opuntia humifusa (prickly pear) were placed outside on the Belmont greenroof to decompose in sunny and shaded environments. The plants were collected over a period of 12 weeks, and data on the masses of the decomposing plants was used …