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2024

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Understanding Orthopaedic Infections: A Conceptual Approach, Gregory Laborde, Christopher Bloise, George Karam Dec 2024

Understanding Orthopaedic Infections: A Conceptual Approach, Gregory Laborde, Christopher Bloise, George Karam

School of Medicine Faculty Publications

BACKGROUND: Memorizing mounds of facts without having an effective conceptual framework to store them is often an unsuccessful learning style because memory frequently fails without understanding. To accomplish this goal, we offer a framework of ideas called "concept maps". Of the many strategies for metacognition (that is, thinking about thinking), concept mapping is proven to improve meaningful and independent learning. We used this approach to guide understanding of common orthopaedic infections. This paper is not meant to serve as an approach on how to treat, but rather as a storage system with the ability to assist in understanding orthopaedic infections. …


Adiposity Throughout Adulthood And Risk Of Young-Onset Breast Cancer Tumor Subtypes In The Young Women's Health History Study, Lydia Marcus Post, Dorothy R. Pathak, Ann S. Hamilton, Kelly A. Hirko, Richard T. Houang, Emily H. Guseman, Dan Sanfelippo, Nicole Bohme Carnegie, L. Karl Olson, Hallgeir Rui, Ann G. Schwartz, Ellen M. Velie Dec 2024

Adiposity Throughout Adulthood And Risk Of Young-Onset Breast Cancer Tumor Subtypes In The Young Women's Health History Study, Lydia Marcus Post, Dorothy R. Pathak, Ann S. Hamilton, Kelly A. Hirko, Richard T. Houang, Emily H. Guseman, Dan Sanfelippo, Nicole Bohme Carnegie, L. Karl Olson, Hallgeir Rui, Ann G. Schwartz, Ellen M. Velie

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

BACKGROUND: The role of adult adiposity in young-onset breast cancer (YOBC) subtype risk is not well understood.

METHODS: In this population-based case (n = 1812)-control (n = 1,381) study of invasive YOBC (ages <50 >years), cases were identified from the Los Angeles County and Metropolitan Detroit Surveillance, Epidemiology, and End Results registries, 2010 to 2015. Area-based, frequency-matched controls were sampled from the 2010 Census. General adiposity [body mass index (BMI)] and central adiposity (waist circumference and waist-to-height ratio) across adulthood and covariates were collected from in-person interviews and measurements. ORs and 95% confidence intervals (CI) for adiposity and YOBC tumor subtypes …


Tourism: A Bridge Between Religions, Deša Karamehmedović Dec 2024

Tourism: A Bridge Between Religions, Deša Karamehmedović

International Journal of Religious Tourism and Pilgrimage

Interreligious dialogue is crucial for cultural, economic, and social progress, fostering cultural development through activities like tourism. To address misunderstandings and biases, continuous development and promotion of interreligious dialogue is essential. This two-way process emphasises the importance of ‘listening and telling’, while respecting differences. Religious tourism serves as a valuable tool for encounters and understanding among diverse communities. This paper tries to address the question of whether there are for interreligious dialogue in tourism that have yet to be applied and could be implemented? The findings from tourism theory indicate that religious encounters primarily take place in sacred places, sacred …


Substance Use Disorder Civil Commitment And Association With Post-Commitment Treatment Retention Among Adult Women, Lydie Ultimo Dec 2024

Substance Use Disorder Civil Commitment And Association With Post-Commitment Treatment Retention Among Adult Women, Lydie Ultimo

Walden Dissertations and Doctoral Studies

The effects of substance abuse are a public health challenge, as evidenced by the prevalence of drug-related overdoses since the year 2000. Involuntary civil commitment (ICC) denotes a legal basis to mandate treatment for people at imminent risk of harm due to substance use disorders (SUD). Grounded on the transtheoretical model stages of change, this quantitative retrospective cohort study analyzed the relationship between mental disorder history, medication for addiction treatment (MAT), and voluntary retention in SUD treatment post-ICC, controlling for age, race/ethnicity, drugs used, housing status, and Department of Children and Families services. Secondary data from the Massachusetts Department of …


Sintesis Etil 2-(4-Formilfenoksi)Asetat Melalui Substitusi Gugus Hidroksil 4-Hidroksibenzaldehida, Arif Fadlan, Moch. Nurhasan Dec 2024

Sintesis Etil 2-(4-Formilfenoksi)Asetat Melalui Substitusi Gugus Hidroksil 4-Hidroksibenzaldehida, Arif Fadlan, Moch. Nurhasan

Chimica et Natura Acta

Senyawa 4-hidroksibenzaldehida merupakan salah satu senyawa fenolat yang mengandung gugus aldehida dan dapat mengalami transformasi struktur melalui berbagai reaksi kimia menghasilkan produk dengan aktivitas biologis yang potensial. Pada penelitian ini struktur senyawa 4-hidroksibenzaldehida dimodifikasi melalui substitusi gugus hidroksil oleh etil kloroasetat dengan perbandingan mol 6:10 (metode A), 5:10 (metode B), dan 2,5:10 (metode C) menghasilkan etil 2-(4-formilfenoksi)asetat. Spektroskopi resonansi magnetik inti 1H dan 13C NMR, inframerah, dan massa digunakan untuk menetapkan struktur hasil sintesis. Hasil penelitian menunjukkan bahwa metode B memberikan produk berupa padatan berwarna putih dengan yield sebesar 70% yang lebih tinggi dibandingkan metode A (yield 23%) dan metode …


Deteksi Mekanisme Efflux Pump Pada Resistensi Bakteri Staphylococcus Haemolyticus, Sampel Pus Klinis Rumah Sakit Pekanbaru, Rexi Dwi Wardana, Maya Savira, Dewi Anggraini, Aisyah Sabrina Amalia, Yuana Nurulita Dec 2024

Deteksi Mekanisme Efflux Pump Pada Resistensi Bakteri Staphylococcus Haemolyticus, Sampel Pus Klinis Rumah Sakit Pekanbaru, Rexi Dwi Wardana, Maya Savira, Dewi Anggraini, Aisyah Sabrina Amalia, Yuana Nurulita

Chimica et Natura Acta

Infeksi adalah masalah kesehatan yang disebabkan oleh mikroorganisme patogen seperti bakteri. Salah satu jenis infeksi yaitu infeksi kulit dan jaringan lunak yang umumnya disebabkan oleh Staphylococcus aureus dan menyebabkan pembentukan pus. Saat ini, telah dilaporkan bahwa kasus spesies CoNS (Coagulase Negative Staphylococcus) seperti Staphylococcus haemolyticus sebagai penyebab infeksi, mengalami peningkatan. Selain itu, spesies ini juga diketahui telah mengalami resistensi terhadap beberapa golongan antibiotik. Dalam penelitian ini dilakukan karakterisasi isolat bakteri klinis dari sampel pus agar yang dilakukan dengan identifikasi mikrobiologi (kultur isolat, pewarnaan Gram dan uji biokimia) pada bakteri patogen (Isolat 3887), dan dilanjutkan dengan identifikasi molekuler, antara lain ekstraksi …


Antioxidant Testing And Identification Of Bioactive Compounds In Ethanol Extract Of Propolis From Various Locations In Indonesia Using Lcms-Qtof, Ade Heri Mulyati, Hanis Alawiyah, Muhamad Fathul Marom, Siti Warnasih Dec 2024

Antioxidant Testing And Identification Of Bioactive Compounds In Ethanol Extract Of Propolis From Various Locations In Indonesia Using Lcms-Qtof, Ade Heri Mulyati, Hanis Alawiyah, Muhamad Fathul Marom, Siti Warnasih

Chimica et Natura Acta

Propolis produced by Trigona sp. stingless bees contains various bioactive substances including alkaloids, flavonoids, polyphenols, saponins, steroids, and terpenoids. The geographical origin of propolis production can influence its composition of secondary metabolites. This study aimed to qualitatively analyze ethanol extracts of propolis from Bintan, Lampung, and Makassar, and evaluate their phenolic and flavonoid contents, as well as antioxidant activities. The extraction method employed kinetic maceration with continuous stirring over 24 hours, using 70% ethanol as the solvent. Additionally, antioxidant activity was assessed using the DPPH method. The qualitative phytochemical analysis revealed that all three ethanol extracts contained alkaloids, flavonoids, and …


24-Methylenecycloartanol Isolated From The Fruit Peel Of Matoa (Pometia Pinnata) And Its Activity As An Antibacterial Against Staphylococcus Aureus And Escherichia Coli, Risyandi Anwar, Steffi Triany Arnov, Ghesta Alifka Putri, Siska Elisahbet Sinaga, Al Arofatus Naini, Unang Supratman Dec 2024

24-Methylenecycloartanol Isolated From The Fruit Peel Of Matoa (Pometia Pinnata) And Its Activity As An Antibacterial Against Staphylococcus Aureus And Escherichia Coli, Risyandi Anwar, Steffi Triany Arnov, Ghesta Alifka Putri, Siska Elisahbet Sinaga, Al Arofatus Naini, Unang Supratman

Chimica et Natura Acta

Triterpenoids are compounds with highly diverse chemical structures and exhibit interesting biological activities such as antiviral, antibacterial, anti-inflammatory, and anticancer properties. The matoa plant (Pometia pinnata), belonging to the genus Pometia from the family Sapindaceae, has been used in traditional medicine and shows potential as an antibacterial agent. The purpose of this research was to isolate and determine the chemical structure of triterpenoids from the peel of the matoa fruit (P. pinnata) and to evaluate their antibacterial activity against Staphylococcus aureus and Escherichia coli. The ethyl acetate extract from the peel of P. pinnata demonstrated significant antibacterial activity. In this …


Development Of Photo Electrocatalytic Chemical Oxygen Demand Design (Pecod) Sensor Using Highly Ordered Titanium Dioxide Nanotube Arrays Electrodes, Chichi Amne Utami, Muhammad Iqbal Syauqi, Sherly Kasuma Warda Ningsih, Rahmat Wibowo, Jarnuzi Gunlazuardi Dec 2024

Development Of Photo Electrocatalytic Chemical Oxygen Demand Design (Pecod) Sensor Using Highly Ordered Titanium Dioxide Nanotube Arrays Electrodes, Chichi Amne Utami, Muhammad Iqbal Syauqi, Sherly Kasuma Warda Ningsih, Rahmat Wibowo, Jarnuzi Gunlazuardi

Chimica et Natura Acta

Population growth, industrialization, and the need to ensure water quality have fostered the demand for analytical methods and tools to determine one of the important values of water quality standards. The oxygen demand of a given water matrix provides valuable information about the presence of organic compounds in a sample. The TiO2-based photoelectrocatalytic COD (PECOD) method offers a faster, more efficient, and more accurate alternative than conventional methods. Highly ordered TiO2 nanotube arrays (HOTNAs) were synthesized by anodizing titanium metal at 45V for 2 hours. HOTNAs/FTO photoanodes are used to oxidize organic compounds in water. HOTNAs/FTO photoanode has a bandgap …


D101n: A Unique And Ill-Understood Familial Als-Related Sod1 Mutant, Analisa Lott Dec 2024

D101n: A Unique And Ill-Understood Familial Als-Related Sod1 Mutant, Analisa Lott

Honors Program Theses and Research Projects

Background: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease, with 90% of documented cases considered sporadic and about 10% showing a hereditary link; such cases are deemed as familial ALS (fALS). Superoxide dismutase (SOD), a copper-zinc binding enzyme that protects cells from damaging free radicals, has been linked to fALS with certain toxic gain of function mutations, such as the D101N mutant. The human SOD1 D101N mutant has been shown to be associated with rapidly progressing neurodegeneration yet is less prone to aggregation than similar mutants, but its deviation from wild-type (WT) SOD1 remains misunderstood.

Objective: Although the D101N …


Prenatal Tobacco Exposure, Brain Subcortical Volumes, And Gray-White Matter Contrast, Troy B. Puga, Gaelle E. Doucet, Grace Thiel Dec 2024

Prenatal Tobacco Exposure, Brain Subcortical Volumes, And Gray-White Matter Contrast, Troy B. Puga, Gaelle E. Doucet, Grace Thiel

Student Publications

Importance Maternal tobacco use during pregnancy (MTDP) remains a major public health challenge. However, the complete spectrum of effects of MTDP is not fully understood.

Objectives To examine the longitudinal associations of MTDP and children’s brain morphometric subcortical volume and gray-white matter contrast (GWC) development.

Design, Setting, and Participants Cohort study of children aged 9 to 10 years at wave 1 (October 2016 to October 2018) and at a 2-year follow-up (wave 2; August 2018 to January 2021; aged 11-12 years) across 21 US sites in the Adolescent Brain Cognitive Development (ABCD) Study. Data were analyzed from October 2023 to …


Inherited Retinal Degenerations And Non-Neovascular Age-Related Macular Degeneration: Progress And Unmet Needs, Jacque L Duncan, Angela Bowman, Amy Laster, Claire Gelfman, David G Birch, Shannon E Boye, Stephen P Daiger, Lucian Del Priore, Donald J Zack, James T Handa Dec 2024

Inherited Retinal Degenerations And Non-Neovascular Age-Related Macular Degeneration: Progress And Unmet Needs, Jacque L Duncan, Angela Bowman, Amy Laster, Claire Gelfman, David G Birch, Shannon E Boye, Stephen P Daiger, Lucian Del Priore, Donald J Zack, James T Handa

Faculty, Staff and Student Publications

Inherited retinal degeneration (IRD) disease and age-related macular degeneration (AMD) are leading causes of irreversible vision loss and blindness. Although significant progress has advanced the field in the past 5 years, significant challenges remain. The current article reviews the accomplishments and research advances that have fueled the development of treatments for patients with IRD and AMD, including the first approved gene-augmentation treatment for RPE65-related retinal degeneration and complement inhibition therapies to slow progression of geographic atrophy (GA) in AMD. The article outlines opportunities to address gaps and unmet needs that should lead to additional progress toward the development of treatments …


Systemic Administration Of A Site-Targeted Complement Inhibitor Attenuates Chronic Stress-Induced Social Behavior Deficits And Neuroinflammation In Mice, Amit Kumar Madeshiya, Brandi Quintanilla, Carl Whitehead, Stephen Tomlinson, Anilkumar Pillai Dec 2024

Systemic Administration Of A Site-Targeted Complement Inhibitor Attenuates Chronic Stress-Induced Social Behavior Deficits And Neuroinflammation In Mice, Amit Kumar Madeshiya, Brandi Quintanilla, Carl Whitehead, Stephen Tomlinson, Anilkumar Pillai

Faculty, Staff and Student Publications

Chronic stress, a risk factor for many neuropsychiatric conditions, causes dysregulation in the immune system in both humans and animal models. Additionally, inflammation and synapse loss have been associated with deficits in social behavior. The complement system, a key player of innate immunity, has been linked to social behavior impairments caused by chronic stress. However, it is not known whether complement inhibition can help prevent neuroinflammation and behavioral deficits caused by chronic stress. In this study, we investigated the potential of a site-targeted complement inhibitor to ameliorate chronic stress-induced changes in social behavior and inflammatory markers in the prefrontal cortex …


Urinary Metal Levels, Cognitive Test Performance, And Dementia In The Multi-Ethnic Study Of Atherosclerosis, Arce Domingo-Relloso, Katlyn E Mcgraw, Susan R Heckbert, Jose A Luchsinger, Kathrin Schilling, Ronald A Glabonjat, Irene Martinez-Morata, Melanie Mayer, Yongmei Liu, Alexis C Wood, Jeff Goldsmith, Kathleen M Hayden, Mohamad Habes, Ilya M Nasrallah, R Nick Bryan, Tanweer Rashid, Wendy S Post, Jerome I Rotter, Priya Palta, Linda Valeri, Timothy M Hughes, Ana Navas-Acien Dec 2024

Urinary Metal Levels, Cognitive Test Performance, And Dementia In The Multi-Ethnic Study Of Atherosclerosis, Arce Domingo-Relloso, Katlyn E Mcgraw, Susan R Heckbert, Jose A Luchsinger, Kathrin Schilling, Ronald A Glabonjat, Irene Martinez-Morata, Melanie Mayer, Yongmei Liu, Alexis C Wood, Jeff Goldsmith, Kathleen M Hayden, Mohamad Habes, Ilya M Nasrallah, R Nick Bryan, Tanweer Rashid, Wendy S Post, Jerome I Rotter, Priya Palta, Linda Valeri, Timothy M Hughes, Ana Navas-Acien

Faculty, Staff and Students Publications

IMPORTANCE: Metals are established neurotoxicants, but evidence of their association with cognitive performance at low chronic exposure levels is limited.

OBJECTIVE: To investigate the association of urinary metal levels, individually and as a mixture, with cognitive tests and dementia diagnosis, including effect modification by apolipoprotein ε4 allele (APOE4).

DESIGN, SETTING, AND PARTICIPANTS: The multicenter prospective cohort Multi-Ethnic Study of Atherosclerosis (MESA) was started from July 2000 to August 2002, with follow-up through 2018. A total of 6303 MESA participants were included. Data analysis was performed from October 12, 2023, to June 13, 2024.

EXPOSURE: Urine samples were collected at baseline …


Chagos Archipelago, Claire Collins, David J. Curnick, Tom Letessier, Joanna Harris Dec 2024

Chagos Archipelago, Claire Collins, David J. Curnick, Tom Letessier, Joanna Harris

School of Biological and Marine Sciences

No abstract provided.


Myeloid Activation Clears Ascites And Reveals Il27-Dependent Regression Of Metastatic Ovarian Cancer, Brennah Murphy, Taito Miyamoto, Bryan S Manning, Gauri Mirji, Alessio Ugolini, Toshitha Kannan, Kohei Hamada, Yanfang P Zhu, Daniel T Claiborne, Lu Huang, Rugang Zhang, Yulia Nefedova, Andrew Kossenkov, Filippo Veglia, Rahul Shinde, Nan Zhang Dec 2024

Myeloid Activation Clears Ascites And Reveals Il27-Dependent Regression Of Metastatic Ovarian Cancer, Brennah Murphy, Taito Miyamoto, Bryan S Manning, Gauri Mirji, Alessio Ugolini, Toshitha Kannan, Kohei Hamada, Yanfang P Zhu, Daniel T Claiborne, Lu Huang, Rugang Zhang, Yulia Nefedova, Andrew Kossenkov, Filippo Veglia, Rahul Shinde, Nan Zhang

Faculty, Staff and Student Publications

Patients with metastatic ovarian cancer (OvCa) have a 5-year survival rate of < 30% due to the persisting dissemination of chemoresistant cells in the peritoneal fluid and the immunosuppressive microenvironment in the peritoneal cavity. Here, we report that intraperitoneal administration of β-glucan and IFNγ (BI) induced robust tumor regression in clinically relevant models of metastatic OvCa. BI induced tumor regression by controlling fluid tumor burden and activating localized antitumor immunity. β-glucan alone cleared ascites and eliminated fluid tumor cells by inducing intraperitoneal clotting in the fluid and Dectin-1-Syk-dependent NETosis in the omentum. In omentum tumors, BI expanded a novel subset of immunostimulatory IL27+ macrophages and neutralizing IL27 impaired BI efficacy in vivo. Moreover, BI directly induced IL27 secretion in macrophages where single agent treatment did not. Finally, BI extended mouse survival in a chemoresistant model and significantly improved chemotherapy response in a chemo-sensitive model. In summary, we propose a new therapeutic strategy for the treatment of metastatic OvCa.


Rna Shielding Of P65 Is Required To Potentiate Oncogenic Inflammation In Tet2-Mutated Clonal Hematopoiesis, Nana Adjoa Ben-Crentsil, Wazim Mohammed Ismail, Maria E Balasis, Hannah Newman, Ariel Quintana, Moritz Binder, Traci Kruer, Surendra Neupane, Meghan C Ferrall-Fairbanks, Jenna Fernandez, Terra L Lasho, Christy M Finke, Mohammed L Ibrahim, Kathy L Mcgraw, Michael Wysota, Amy L Aldrich, Christopher B Ryder, Christopher T Letson, Joshua Traina, Amy F Mclemore, Nathalie Droin, Aditi Shastri, Seongseok Yun, Eric Solary, David A Sallman, Amer A Beg, Li Ma, Alexandre Gaspar-Maia, Mrinal M Patnaik, Eric Padron Dec 2024

Rna Shielding Of P65 Is Required To Potentiate Oncogenic Inflammation In Tet2-Mutated Clonal Hematopoiesis, Nana Adjoa Ben-Crentsil, Wazim Mohammed Ismail, Maria E Balasis, Hannah Newman, Ariel Quintana, Moritz Binder, Traci Kruer, Surendra Neupane, Meghan C Ferrall-Fairbanks, Jenna Fernandez, Terra L Lasho, Christy M Finke, Mohammed L Ibrahim, Kathy L Mcgraw, Michael Wysota, Amy L Aldrich, Christopher B Ryder, Christopher T Letson, Joshua Traina, Amy F Mclemore, Nathalie Droin, Aditi Shastri, Seongseok Yun, Eric Solary, David A Sallman, Amer A Beg, Li Ma, Alexandre Gaspar-Maia, Mrinal M Patnaik, Eric Padron

Faculty, Staff and Student Publications

This work identifies MALAT1 as a requisite downstream effector of oncogenic feedforward inflammatory circuits necessary for the development of TET2-mutated CH and fulminant myeloid malignancy. We elucidate a novel mechanism by which MALAT1 "shields" p65 from dephosphorylation to potentiate this circuit and nominate MALAT1 inhibition as a future therapeutic strategy.


Optimizing Lab Methods For Consistent Rice Milling Analysis, Samuel Olayiwola Olaoni, Bindu Regonda, Kaushik Luthra, Griffiths Atungulu Dec 2024

Optimizing Lab Methods For Consistent Rice Milling Analysis, Samuel Olayiwola Olaoni, Bindu Regonda, Kaushik Luthra, Griffiths Atungulu

Food Science Faculty Publications and Presentations

Background and Objectives

Milling is one of the most important postharvest processes in rice production. Traditionally, the McGill #2 mill has been used for lab milling to assess rice milling performance as per the recommendation of the Federal Grain Inspection Service (FGIS). However, as the FGIS is phasing out the use of the McGill #2 mill, there is a need to recalibrate milling assessments for standardized milling evaluation across various labs. Thus, the objective of this study was to assess the milling performance of three laboratory mills (McGill #2, Satake, and Zaccaria mills) on the head rice yield (HRY), milled …


Onset And Progression Of Disease In Nonhuman Primates With Pde6c Cone Disorder, Monica Ardon, Lily Nguyen, Rui Chen, Jeffrey Rogers, Tim Stout, Sara Thomasy, Ala Moshiri Dec 2024

Onset And Progression Of Disease In Nonhuman Primates With Pde6c Cone Disorder, Monica Ardon, Lily Nguyen, Rui Chen, Jeffrey Rogers, Tim Stout, Sara Thomasy, Ala Moshiri

Faculty, Staff and Students Publications

PURPOSE: The California National Primate Research Center contains a colony of rhesus macaques with a homozygous missense mutation in PDE6C (R565Q) which causes a cone disorder similar to PDE6C achromatopsia in humans. The purposes of this study are to characterize the phenotype in PDE6C macaques in detail to determine the onset of the cone phenotype, the degree to which the phenotype progresses, if heterozygote animals have an intermediate phenotype, and if rod photoreceptor function declines over time.

METHODS: We analyzed spectral-domain optical coherence tomography (SD-OCT), fundus autofluorescence (FAF), and electroretinography (ERG) data from 102 eyes of 51 macaques (aged 0.25 …


A Preoperative Window-Of-Opportunity Study Of Oral Serd, Imlunestrant, In Newly Diagnosed Er-Positive, Her2-Negative Early Breast Cancer: Results From The Ember-2 Study, Patrick Neven, Rebecca Aft, Et Al. Dec 2024

A Preoperative Window-Of-Opportunity Study Of Oral Serd, Imlunestrant, In Newly Diagnosed Er-Positive, Her2-Negative Early Breast Cancer: Results From The Ember-2 Study, Patrick Neven, Rebecca Aft, Et Al.

2020-Current year OA Pubs

PURPOSE: Imlunestrant is an oral selective estrogen receptor degrader with favorable safety and preliminary efficacy in patients with advanced breast cancer. Pharmacodynamic (PD) biomarker data can optimize drug dosing; in this study, we present PD data from the EMBER-2 study.

PATIENTS AND METHODS: Postmenopausal women with untreated, operable estrogen receptor (ER)-positive, HER2-negative early breast cancer were randomized to 400 versus 800 mg of imlunestrant daily for ∼2 weeks before surgery. A single arm study tested a daily dose of 200 mg. PD biomarker changes (ER, progesterone receptor, Ki-67 by IHC, and mRNA expression of ER-related genes) were evaluated in paired …


Cover And Contents Dec 2024

Cover And Contents

Turkish Journal of Agriculture and Forestry

No abstract provided.


Role Of Nanoparticles In Mitigating Chromium Toxicity: Implications, Mechanisms, Andfuture Prospects, Muhammad Umair Hassan, Adnan Noor Shah, Muhammad Nawaz, Muhammad Inzamam-Ul-Haq, Tahir Abbas Khan, Mehmood Ali Noor, Fang Luo, Rehab O. Elnour, Mohamed Hashem, Huang Guoqin Dec 2024

Role Of Nanoparticles In Mitigating Chromium Toxicity: Implications, Mechanisms, Andfuture Prospects, Muhammad Umair Hassan, Adnan Noor Shah, Muhammad Nawaz, Muhammad Inzamam-Ul-Haq, Tahir Abbas Khan, Mehmood Ali Noor, Fang Luo, Rehab O. Elnour, Mohamed Hashem, Huang Guoqin

Turkish Journal of Agriculture and Forestry

Chromium (Cr) is an extremely toxic metal for all living organisms and its concentration in the environment is constantly increasing due to human activities. Plants quickly absorb the Cr subsequently, it enters the human food chain and poses serious health issues. Chromium toxicity causes a serious reduction in plant growth by inducing oxidative damage and disturbing protein synthesis, enzyme activity, and nutrient uptake. Plants use diverse mechanisms to mitigate the Cr toxicity however, they are inadequate against higher concentrations of Cr. Thus is essential to diminish Cr toxicity and increase the ability of plants to tolerate Cr stress. Nano-particles (NPs) …


Influence Of Nitrate Levels On Plant Growth And Carbon And Nitrogen Metabolismin Cucumber (Cucumis Sativus L.) Under Low Light Stress, Syed Aizaz Ali Shah, Yuzi Shi, Jing Nie, Xuehui Yao, Yicong Guo, Muhammad Ahmad, Syed Atizaz Ali Shah, Faisal Hayat, Yasmin Niamat, Hali̇l İbrahim Öztürk, Xiaolei Sui Dec 2024

Influence Of Nitrate Levels On Plant Growth And Carbon And Nitrogen Metabolismin Cucumber (Cucumis Sativus L.) Under Low Light Stress, Syed Aizaz Ali Shah, Yuzi Shi, Jing Nie, Xuehui Yao, Yicong Guo, Muhammad Ahmad, Syed Atizaz Ali Shah, Faisal Hayat, Yasmin Niamat, Hali̇l İbrahim Öztürk, Xiaolei Sui

Turkish Journal of Agriculture and Forestry

Photosynthesis is critically dependent on both adequate light and nitrogen availability. In controlled agricultural environmentswith limited natural light, cucumber faces substantial challenges, including reduced photosynthetic efficiency and biomass accumulation.Nitrogen (N) is a vital component for the synthesis of various macromolecules, metabolites, and signaling molecules in plants. This studyassessed the impact of different nitrate levels (LL-N, LL-1/2N, and LL-2N) on the physiological, biochemical, and metabolic responsesof cucumber under low light conditions (80–100 μmol m–2 s–1 photosynthetic photon flux density) in comparison to standard light(400–500 μmol m–2 s–1 photosynthetic photon flux density) and unchanged nitrate. We observed that increasing nitrate levels to …


In Silico Analysis Of Three-Amino Acid Loop Extension (Tale) Proteins In Phaseolusvulgaris L. And Investigation Of Their Transcript Levels In Response To Drought Stress, Fatma Nur Avci, Tarik Kirlioğlu, Aybüke Okay, Emi̇ne Sümer Aras, İlker Büyük Dec 2024

In Silico Analysis Of Three-Amino Acid Loop Extension (Tale) Proteins In Phaseolusvulgaris L. And Investigation Of Their Transcript Levels In Response To Drought Stress, Fatma Nur Avci, Tarik Kirlioğlu, Aybüke Okay, Emi̇ne Sümer Aras, İlker Büyük

Turkish Journal of Agriculture and Forestry

Drought represents a major global threat to the environment, thus leading to food insecurity. Transcription factors (TFs) have a significant role in regulating the expression of stress-related genes. TALE genes, a type of TF, are known to regulate important biological processes like the maintenance of shoot apical meristems and root formation in plants. In this study, 35 TALE genes were identified and they were found to be categorized into KNOX-like homeodomain (KNOX) and BLH/BELL-like subfamilies in Phaseolus vulgaris according to the phylogenetic analysis. The detailed characterization of PvTALE genes using in silico analyzes further showed that segmental duplications predominate in …


Occurrence And Biodiversity Of Cyst Nematodes In Wheat And Barley Cultivation Areas Ofuşak Province, Türkiye, Seli̇n Türkay, Ebubeki̇r Yüksel, Refi̇k Bozbuğa, Di̇lek Di̇nçer, Ati̇lla Öcal, Furkan Ulaş, Muhammad Sameeullah, Abdelfettah Dababat, Mustafa İmren Dec 2024

Occurrence And Biodiversity Of Cyst Nematodes In Wheat And Barley Cultivation Areas Ofuşak Province, Türkiye, Seli̇n Türkay, Ebubeki̇r Yüksel, Refi̇k Bozbuğa, Di̇lek Di̇nçer, Ati̇lla Öcal, Furkan Ulaş, Muhammad Sameeullah, Abdelfettah Dababat, Mustafa İmren

Turkish Journal of Agriculture and Forestry

Plant parasitic nematodes (PPNs) are one of the major threats to various crops including cereals. In wheat and barleyproduction, the profitability of cultivation heavily depends on the management of cyst nematodes (CNs), especially on Heteroderaavenae, H. filipjevi, and H. latipons. In this study, field surveys were conducted in wheat and barley cultivation systems of Uşak Provinceto reveal the presence and diversity of PPNs. In total, 80 wheat and barley fields were surveyed, and samples (soil and root) wereprocessed for the isolation and identification of PPNs. The PPN genera were identified to the species level based on morphologicaland morphometric characters. CNs …


Control Of Mango Anthracnose (Colletotrichum Gloeosporioides) By Essential Oil Mixture, Chau Trung Duong, Huynh Thi Phuong Thao, Doan Minh Khang, Nguyen Thi Nhu Y, Tran Chi Nhan, Bui Thi Cam Huong, Nguyen Trong Tuan, Nguyen Thi Ngoc Truc, Dương Minh Tuệ, Luu Thai Danh Dec 2024

Control Of Mango Anthracnose (Colletotrichum Gloeosporioides) By Essential Oil Mixture, Chau Trung Duong, Huynh Thi Phuong Thao, Doan Minh Khang, Nguyen Thi Nhu Y, Tran Chi Nhan, Bui Thi Cam Huong, Nguyen Trong Tuan, Nguyen Thi Ngoc Truc, Dương Minh Tuệ, Luu Thai Danh

Turkish Journal of Agriculture and Forestry

Mixing two or more essential oils (EOs) may increase effectiveness of mango anthracnose control. In this study, EOs from a wide range of plant materials were hydro-distilled and chemically characterized. EOs were tested against in vitro growth of Colletotrichum gloeosporioides. EOs with the highest antifungal toxicity were selected for the interactive experiments. The results showed that orange had the highest extraction yield (4.94%), followed by lemon, pomelo, citronella, turmeric, ginger, lemongrass (LG), cinnamon bark (CB), cinnamon leaf (CL) and basil. Trans-cinnamaldehyde was the most abundant compound of CB (91.3%) and CL (94.1%) EO. Limonene was principle constituent of orange (97%), …


Combined Physiological And Biochemical Analysis And Molecular Biotechnology For Atrazine Residue Reduction In Soybeans, Fenglan Hu, Yan Ding Dec 2024

Combined Physiological And Biochemical Analysis And Molecular Biotechnology For Atrazine Residue Reduction In Soybeans, Fenglan Hu, Yan Ding

Turkish Journal of Agriculture and Forestry

To address the problem of atrazine residue in soybeans affecting the ecological environment and human health, in the presentstudy it is proposed to combine the bioorganic fertilizer DNBF10 and the highly efficient degrading bacterial strain AT-b3 with themagnetic biochar carrier MBC to form a novel DMBC-P bioremediation technology. The results indicated that the DMBC-P technologycould effectively reduce the residual amount of atrazine in soybeans and significantly enhance their growth and physiological indexes bypromoting atrazine degradation and phosphorus utilization and reducing oxidative stress. At the physiological and biochemical levels,DNBF10 significantly alleviated atrazine-induced oxidative stress, reducing the IBRv2 values to 1.84 and …


Optimal Pollen Viability And Vigor Among Varieties Of Tagnanan Tall Coconut(Cocos Nucifera L.), Xi Yun Liew, Mohd Norsazwan Ghazali, Mohd Firdaus Ismail, Zarina Abd Ghafar, Mohd Syarbani Bin Ismar, Vasudevan Venkatachalam, Uma Rani Sinniah Dec 2024

Optimal Pollen Viability And Vigor Among Varieties Of Tagnanan Tall Coconut(Cocos Nucifera L.), Xi Yun Liew, Mohd Norsazwan Ghazali, Mohd Firdaus Ismail, Zarina Abd Ghafar, Mohd Syarbani Bin Ismar, Vasudevan Venkatachalam, Uma Rani Sinniah

Turkish Journal of Agriculture and Forestry

Controlled pollination, involving the transfer of pollen from Tagnanan Tall palm (male parent) to the Malayan Yellow or Red dwarf (female parent) is essential for producing MATAG coconut hybrids. However, the pollen from Tagnanan Tall (TAGT), usedin hybridization, has been reported to have a germination percentage of less than 40%. This is further complicated by Tagnanan Tall varieties varying in color, TAGT Orange, TAGT Gold, and TAGT Green. TAGT Orange is claimed to have lower pollen viability than TAGT Gold and Green. Hence, a study was conducted to compare inflorescence characteristics, pollen yield, size, viability, and vigor of three Tagnanan …


Bioethanol Yield Of The Sorghum × Sudangrass Hybrid Under Arid And Semiaridconditions: Nitrogen Dose Effects, Orthogonal Comparisons, And Component Analyses, Hali̇t Tutar Dec 2024

Bioethanol Yield Of The Sorghum × Sudangrass Hybrid Under Arid And Semiaridconditions: Nitrogen Dose Effects, Orthogonal Comparisons, And Component Analyses, Hali̇t Tutar

Turkish Journal of Agriculture and Forestry

The sorghum x sudangrass hybrid is highly significant as a biofuel crop due to its high biomass production, drought tolerance, ability to adapt to various climatic conditions, and high sugar content in its stems. This research aimed to determine the effects of six different nitrogen dose treatments on ethanol yield, yield parameters, and fertilizer use relationships in sorghum x sudangrass hybrid plants at two locations in 2021 and 2022. The experiment was established according to the randomized block design with three replicates. Nitrogen treatments were applied as N0 (0 kg da-1), N5 (5 kg da-1), N10 (10 kg da-1), N15 …


Allostatic Load, Educational Attainment, And Risk Of Cancer Mortality Among Us Men, Cynthia Li, Sydney P Howard, Charles R Rogers, Sydney Andrzejak, Keon L Gilbert, Keith J Watts, Malcolm S Bevel, Myles D Moody, Marvin E Langston, Judah V Doty, Adetunji T Toriola, Darwin Conwell, Justin X Moore Dec 2024

Allostatic Load, Educational Attainment, And Risk Of Cancer Mortality Among Us Men, Cynthia Li, Sydney P Howard, Charles R Rogers, Sydney Andrzejak, Keon L Gilbert, Keith J Watts, Malcolm S Bevel, Myles D Moody, Marvin E Langston, Judah V Doty, Adetunji T Toriola, Darwin Conwell, Justin X Moore

2020-Current year OA Pubs

IMPORTANCE: Health disparities among racial and ethnic minoritized populations, particularly for cancer mortality rates, remain a major public health concern. Men from underrepresented backgrounds (Black and Hispanic men, specifically) face the pervasive effects of discrimination in their daily lives, which also contribute to the complex associations among allostatic load (a marker of chronic stress), educational opportunities, and elevated risks of cancer mortality.

OBJECTIVE: To elucidate the associations among educational attainment, allostatic load, and cancer mortality risk among men.

DESIGN, SETTING, AND PARTICIPANTS: This is a retrospective cohort analysis of data from the National Health and Nutrition Examination Survey, a nationally …