Digital Commons Network^™

System Architecture For Cross-Domain Intent Orchestration, Institutional Latency Mitigation, And Distributed Post-Labor Commerce, Christopher L. Eckes

Defensive Publications Series

This disclosure specifies a multi-tiered software and network architecture designed to resolve the systemic bandwidth, cognitive load, and training-data saturation bottlenecks (collectively termed the Epistemic Squeeze) that occur when linear human operational capacity interfaces with exponentially scaling technological and informational systems. The architecture establishes a structured, three-tiered human-machine orchestration environment that shifts human input from low-level manual execution to high-abstract intent orchestration. By introducing a middleware context-translation layer (AI Scaffolding), the system automates semantic embedding mapping across hyper-isolated, domain-specific ontologies, drastically reducing the multi-decade training lifecycle traditionally required to reach technological frontiers.

Furthermore, to mitigate the socio-economic displacement of human …

The Helical Manifold Hypothesis: Time As A Latency Function Of Volumetric Quantum Wave Collapse, Christopher L. Eckes

Defensive Publications Series

This paper introduces the Helical Manifold Hypothesis (HMH), a unified geometric and informational framework that models 3D space and linear time as emergent macroscopic phenomena derived from a fundamental, timeless 2D quantum substrate. We propose that baseline energy fields exist on this substrate as highly coiled, localized topological structures. Upon interaction or observation, these wave functions undergo an asymmetric volumetric collapse, uncoiling outward into 3D space to form a visible matter vector, while their anti-matter counterparts remain anchored to the negative side of the substrate. This split establishes physical spacetime coordinates (x, y, z, t). Under this framework, linear time …

Technical Specification: Definitive Master Taxonomy And Systemic Architectural Directory For The Cognitive Grids Cores (Papers 1–117), Christopher L. Eckes

Defensive Publications Series

This specification establishes the definitive, system-wide architectural index and organizational taxonomy for the Christopher L. Eckes defensive publication corpus, spanning Papers 1 through 117. Historically, open-source development and prior art disclosures suffer from structural fragmentation, allowing centralized entities to locate and exploit isolation gaps between software layers and physical hardware implementations.

This master directory resolves this vulnerability by executing a top-down, text-based semantic alignment that maps the entire 117-paper footprint into eight highly dense, interconnected Technical Domains. By establishing the precise mathematical and logical dependencies linking low-level physical fluid dynamics, material manufacturing recipes, energy transduction systems, non-silicon quantum backbones, sovereign …

Technical Specification: Omnidirectional Multi-Vector Omni-Resonant Memory Substrate For High-Density Sovereign Storage, Christopher L. Eckes

Defensive Publications Series

This specification defines the physical architecture, material composition, manufacturing parameters, and control mathematics for an Omnidirectional Multi-Vector Omni-Resonant Non-Volatile Storage Matrix. Engineered to operate as a completely self-healing, ambient-temperature memory baseline for sovereign, main-duty processing networks, this specification eliminates external code or library references, providing an exhaustive, standalone manual for hardware replication.

We formalize four parallel physical storage channels: a mechanical acoustofluidic phase-change grid (A-RAM) deploying a Topologically Protected Cymatic Electrolyte Matrix (TPCEM) [Eckes], a stroboscopic optical emission hole-burning layer validated via tabletop three-dimensional photoemission orbital tomography (3D-POT), an electromagnetic magnetohydrodynamic (MHD) vortex confinement cell, and an organic lipid-encapsulated solitonic …

Evaluating The Potential Of Cajanus Cajan (L.) Millsp. Root To Improve Atopic Dermatitis With Different Anti-Inflammatory Models And Active Compounds, Shu-Er Yang, Xiang-Ming Cai, Yu-Wen Chu, Jen-Chieh Tsai, Mey-Fann Lee, Tuzz-Ying Song

Journal of Food and Drug Analysis

Atopic dermatitis (AD) is a chronic inflammatory disease characterized by recurrent bacterial infections that cause pruritus, erythema, xerosis and thickening. Cajanus cajan root extract prepared with 95% ethanol (EECR95) has been shown to possess antioxidant, anti-inflammatory, and antibacterial properties in previous studies. This study aimed to evaluate EECR95’s ability to improve AD by inhibiting methicillin-resistant Staphylococcus aureus (MRSA) growth and reducing inflammation. This study found EECR95 effectively inhibits MRSA growth (IC₅₀ = 103.74 μg/mL) and reduces pro-inflammatory cytokine production in an MRSA-keratinocyte-macrophage model. LC/MS/MS analysis revealed the presence of active compounds- flavonoids, isoflavones, and flavonoid glycosides, highlighting EECR95's potential …

Development And Clinical Validation Of An Artificial Intelligence—Assisted Radiographic System For Predicting Periodontal Pocket Severity Using Full-Mouth Radiographs, Chia-Tze Kaokao

Articles in Press

No abstract provided.

Application Of Medical Imaging Examinations For Temporomandibular Disorders Under Taiwan’S National Health Insurance System, Yu-Ling Wu

Articles in Press

No abstract provided.

Clara S. Ludlow: Mississippi A & M Graduate And American Military Entomology Pioneer, Bradley Brazzeal

Midsouth Entomologist

The systematic study of the mosquitoes of the world did not begin until the early years of the 20^th century. Among the early entomologists to specialize in the field was Clara S. Ludlow, who graduated from Mississippi Agricultural and Mechanical College. Her research began in the Philippines in 1901, while American troops were still fighting in the Philippine-American War, and for over 20 years she researched mosquitoes in connection with the U.S. Army. This article explores Ludlow’s scientific career and the legacy of her research.

Family Religious Socialization Index: Development And Preliminary Validation, Kaelie Rene Crockett

Theses and Dissertations

A key area of interest for religious scholars is how religious beliefs are passed across generations, or religious socialization. To expand this field of study, a theoretically grounded, validated measure of this construct is needed. This article describes the development and validation of the Family Religious Socialization Index (FRSI), a multi-informant, multidimensional assessment of the processes through which parents socialize religion and faith in their children. Based on Social Cognitive Theory and through a rigorous development and validation process, three subscales were developed to represent the primary processes of religious socialization. The FRSI consists of two parallel scales, a parent …

Oregon State Rank Assessment For Deer-Cabbage (Nephrophyllidium Crista-Galli), Lindsey K. Wise

Institute for Natural Resources Publications

Oregon state conservation status assessment for Deer-cabbage (Nephrophyllidium crista-galli) using NatureServe methodology, 2026.

Research Replays Evolution To Test Nature's Predictability, Clara Turnage

University of Mississippi News

OXFORD, Miss. – Researchers at the University of Mississippi are watching 1,000 generations of yeast and algae as they grow and change in real time to better understand how species evolve together.

Miconazole As A Repurposed Anticancer Candidate For Prostate Cancer, Eswara Naga Hanuma Kumar Ghali, Lindsey Shim, Rajasekhar Baru, Anupam Dhasmana, Ryan Chang, Sung Yun Jung, Rahul Tiwari, Neeraj Chauhan, Vivek K. Kashyap, Sheema Khan, Diane Nguyen, Subhash C. Chauhan, Murali Mohan Yallapu

School of Medicine Publications

Prostate cancer is one of the major health concerns, with increasing incidence and persistent therapeutic resistance worldwide. Despite various available treatments (radiation therapy, chemotherapy, hormone therapy, cryotherapy, biological therapy, and high-intensity focused ultrasound), patients still show treatment-related side effects over many years. These challenges highlight the urgent need for novel and safe therapeutic strategies. In the present study, we repurposed five FDA-approved antifungal agents, namely natamycin (NM), terbinafine hydrochloride (TH), ketoconazole (KZ), miconazole (MZ), and clotrimazole (CZ), as they can modulate conserved cellular processes, including sterol metabolism and mitochondrial function, which are increasingly recognized as critical determinants of cancer cell …

Runx1+23 Enhancer Marks Erythro-Megakaryocyte Lineages In Early Waves Of Hematopoiesis In Human Esc Differentiation, Chika Nishida, Michihiro Kobayashi, Alina Syed, Philipp Kramer, Haizi Cheng, Pamela L Wenzel, Motomi Osato, Jason David Chobirko, Andrew Grimson, Igor I Slukvin, Brian R Davis, Momoko Yoshimoto

The Brown Foundation: Institute of Molecular Medicine

No abstract provided.

Belonging And Whole Person Formation In Graduate Education: A Conceptual Framework For Student Flourishing, Cynthia Hickman

Papers

Graduate students experience substantial academic, personal, and professional demands that can negatively affect well-being and persistence. For students enrolled in professional programs, belonging may develop within two overlapping communities: the academic institution and the emerging profession. Institutional and professional belonging can provide connection, support, engagement, and opportunities for identity and professional development. This paper synthesizes literature on these two forms of belonging and proposes a conceptual framework describing their potential relationship with whole-person formation and flourishing. Whole-person formation extends graduate education beyond knowledge acquisition and professional competence to include development across interconnected dimensions of the person. Within the proposed framework, …

Identifying The Brain Circuits Involved In Religious Obsessive-Compulsive Disorder, Kiana Bunnell

Theses and Dissertations

Obsessive-compulsive disorder (OCD) is an often-debilitating psychiatric disorder involving a pattern of obsessive thoughts and compensatory compulsions. Symptoms tend to be chronic, leading to substantial emotional burden and significant impairment across multiple domains of daily functioning. Previous research has identified some consistency in the brain regions implicated in OCD. In particular, cortico-striato-thalamo-cortical (CSTC) circuitry has been linked to behavioral features commonly observed in OCD. Moreover, some studies suggest that distinct patterns of brain activation and functional connectivity may be associated with different OCD symptom dimensions, though findings have not been consistent. One symptom dimension of OCD (scrupulosity) is characterized by …

Don't Inject, I Object: Exploring Deferral Of Vaccination For Unaccompanied Alient Children In Custodial Care, Michelle Denamur

University of Dayton Law Review

No abstract provided.

Dosimetric Comparison Of Hybrid 3d Conformal Radiation Therapy And Volumetric Modulated Arc Therapy Versus Vmat-Only Planning For Accelerated Partial Breast Irradiation, Erjona Jusufi

Masters Projects

Abstract

Purpose: To compare dosimetric outcomes between volumetric modulated arc therapy (VMAT)-only and hybrid VMAT plus three-dimensional conformal radiotherapy (3D-CRT) techniques for accelerated partial breast irradiation (APBI) in patients with early-stage left-sided breast cancer.

Methods and Materials: Thirty patients treated with APBI at a single institution were retrospectively replanned using both VMAT-only and hybrid (VMAT + 3D-CRT) techniques. All plans were prescribed 26 Gy in 5 fractions. Each patient was planned using the same target volumes, optimization objectives, and evaluation criteria for both techniques. Planning target volume (PTV) coverage, conformity index (CI), homogeneity index (HI), hotspot control, organ-at-risk (OAR) doses, …

K–3 Teachers’ Perspectives Regarding Learnable Intelligence As A Developmental Target And Their Advocacy For Students’ Cognitive Capabilities, Eleanor Nkechi Maduako

Walden Dissertations and Doctoral Studies

Extensive research shows the brain is malleable and, with experience and knowledge, intelligence can grow. The research problem addressed through this study was that the extent of early childhood educators' knowledge of learnable intelligence and their advocacy for advancement of children’s cognitive capabilities as a developmental goal were unknown. Guided by Perkins’s theory of learnable intelligence, the purpose of this basic qualitative study was to explore K–3 teachers’ perspectives on learnable intelligence as a developmental target and how they advocate for children’s cognitive capabilities in their classrooms. In vivo and axial coding of data from semistructured interviews with 12 participants …

Comparing Non-Invasive Survey Methods For Southern Flying Squirrels (Glaucomys Volans) At The Western Edge Of Their Range, Jay E. Winfield, Jeremy A. White

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

The southern flying squirrel (Glaucomys volans) is a threatened species in Nebraska that occurs along the Missouri River in the southeastern corner of the state. Recently, a population was discovered in the city of Lincoln, but it is unknown whether this population represents a natural range expansion from the Missouri River population or whether it is isolated and results from a human-assisted movement. A survey of southern flying squirrels in Nebraska is needed, but surveys of this elusive species are challenging. This study investigated and compared two noninvasive survey techniques for rapid detection of flying squirrels: acoustic detectors …

Decision Advantage In Cognitive Warfare, Part 1, John Murray, Elise Annett, James Giordano

Strategic Insights

This commentary considers how artificial intelligence and rapidly evolving information environments are changing the conditions for military decision advantage. Building on the OODA loop and the expanded dOODAc framework, the authors argue that effective decision-making depends not only on speed and accuracy, but also on maintaining alignment between institutional cognition and an operational environment that continues to change during the decision cycle. The article introduces temporal synchronization as an important dimension of decision advantage in cognitive warfare, highlighting the challenge of keeping military decisions relevant as informational, behavioral, psychological, and social conditions evolve.

The Defining Role Of Ago4 And Its Catalytic Activity During De Novo Rna-Directed Dna Methylation, Tianyi Li

Arts & Sciences Graduate Student Theses and Dissertations

Plant transposable elements and transgenes are continuously targeted for transcriptional repression via the pathway of RNA-directed DNA methylation (RdDM). Although perpetual RdDM of the endogenous genomic loci has been well studied in the field, much less is known about the de novo RdDM pathway, the pioneering round of DNA methylation responsible for triggering and initiating silencing of new transgenes. Despite being two distinct pathways, both perpetual and de novo mechanisms of RdDM require the production of small interfering RNAs (siRNAs) and the key proteins of the ARGONAUTE4 (AGO4) clade. However, the order and likely mechanism of recruitment of AGO4 to …

Hypnotherapists’ Perspectives On Using Hypnosis To Address Somatic Symptoms In Clients With Psychological Distress, Tina Wilkerson

Walden Dissertations and Doctoral Studies

Somatic symptoms accompany psychological distress and can affect well-being. Hypnosis has demonstrated effectiveness in reducing psychological distress and related somatic symptoms, but limited research has explored hypnotherapists’ perspectives on its clinical application. The purpose of this qualitative phenomenological study was to explore the experiences of licensed hypnotherapists with 3 years of experience using hypnosis to treat adults experiencing somatic symptoms associated with psychological distress. Guided by Engel’s biopsychosocial model and Hilgard’s neodissociation theory, data were collected through semistructured interviews with 10 licensed hypnotherapists and analyzed using phenomenological reduction and thematic analysis. Analysis resulted in four primary themes: (a) mind–body connection …

Pdf Full Issue, Rosalind L. Raby

Journal of Comparative & International Higher Education

No abstract provided.

Closing The Gap In Offshore Wind Environmental Evidence Chains: A Workshop-Derived White Paper, Jiaxin Chen, Lilian Lieber, Matthew Palmer, Dan Lear, Deborah Greaves

School of Biological and Marine Sciences

Offshore wind development is accelerating at a time when environmental assessment is increasingly required to support timely consenting, cumulative-effects understanding, nature recovery, regional planning, floating offshore wind deployment and public trust. The workshop underpinning this White Paper was convened in recognition that the sector's central challenge is no longer simply a lack of data, but the weak connection between data, monitoring approaches, models, uncertainty, governance and decision-making.Environmental monitoring often remains project-specific and receptor-focused, while models remain component-specific or scenario-specific. Data systems are similarly fragmented across owners, repositories, formats, access arrangements and project lifecycle stages. Yet regulators and statutory advisers require …

Social Prescribing For People In Vulnerable Situations In Europe: Protocol For A Process Evaluation Of An Rct In Eight Countries, Kerryn Husk, Elizabeth Gilmour, Stephanie Tierney, Debra Westlake, Anuschka Arni, Hendrik Napierala, Farhad Rezvani, Marius Dierks, Wolfram J. Herrmann

Peninsula Medical School

Objective Social prescribing is a pathway that connects individuals to non-clinical services. It supports and addresses social needs, such as those related to loneliness, housing instability and mental health. Social Prescribing Europe (SP-EU), a European Union funded project, seeks to co-create an adaptation of the social prescribing pathway based on the needs of the following target groups: LGBTIQ+ people, refugees and first-generation immigrants, older people living alone. This adapted social prescribing pathway will be tested in a pragmatic randomised controlled trial (RCT) in ten hubs, covering eight countries, across Europe. The aim of this process evaluation is to explore the …

Institute For Global Health And Development : Issue 14 - April-June 2026, Institute For Global Health And Development

IGHD Newsletters

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Interplay Between Patterning And Morphogenesis During Zebrafish Embryonic Development, Chia-Teng Chang

Arts & Sciences Graduate Student Theses and Dissertations

Patterning and morphogenesis occur concurrently during embryonic development. In many contexts, both processes are regulated by morphogen signaling: morphogens specify spatially organized cell identities while also influencing the cell behaviors that shape tissues. This creates a reciprocal problem. Morphogen signaling can affect how cells move, while cell movement can change how cells experience and interpret morphogen signals. This dissertation investigates this reciprocal problem during zebrafish gastrulation and neurulation. First, it examines how the ventral-to-dorsal bone morphogenetic protein (BMP) activity gradient regulates germ-layer morphogenesis during gastrulation. BMP signaling is known to pattern dorsal–ventral cell fate and regulate mesodermal convergence and extension …

Transient Activation Of Potent Progenitor Cells Is Required For Spinal Cord Regeneration, Chase Alexander Weinholtz

Arts & Sciences Graduate Student Theses and Dissertations

Mammalian spinal cord injury is an intractable biomedical problem driven by interlocking maladaptive cellular responses that prioritize acute stabilization over long-term recovery. However, this deficient regenerative capacity is not an inherent limitation. The zebrafish, for example, capably regenerates and regains motor function with 2 months of a full transection injury. This ability is thought to rely on the transient expansion of stem cell-like progenitors marked by sox2 expression. Yet our understanding of the identities and contributions of this crucial population remains limited. Here, we determine the molecular identities and cellular contributions of sox2+ progenitors during innate spinal cord repair in …

Application And Development Of Continuum Treatments In Photodetachment Of Anions, Pratichhya Adhikari

Arts & Sciences Graduate Student Theses and Dissertations

This dissertation aims to provide deeper insight into understanding the dynamics of the photodetached electrons and the nature of the parent species. The dissertation provides examples of quasi-bound states of the anion embedded in the continuum of states associated with the neutral species, and shows how they manifest in experimental data, deviating from expectations of direct detachment. This dissertation is primarily computational and applies and develops electronic-structure and continuum models, respectively, and a newly implemented physical dipole treatment of the photoelectron to account for these resonances and to interpret experimental photoelectron imaging data. The content of the dissertation is divided …

An Interdisciplinary Approach To Sampling Hard Rock Cores Of The Oceanic Crust For Microbiological And Biogeochemical Research, William J. Brazelton, Oscar Cavazos, Jordyn A. Robare, Gordon Southam, Johanna Suhonen, Fengping Wang, Susan Q. Lang, Andrew Mccaig, Peter Blum, Natsue Abe, Remi Coltat, Jeremy R. Deans, Kristin L. Dickerson, Marguerite Godard, Barbara E. John, Frieder Klein, Rebecca Kuehn, Kuan-Yu Lin, C. Johan Lissenberg, Haiyang Liu, Ethan L. Lopes, Toshio Nozaka, Andrew J. Parsons, Vamdev Pathak, Mark K. Reagan, C. Geoffrey Wheat

School of Geography, Earth and Environmental Sciences

Studying life in the deep, rocky subseafloor involves many layers of technological and methodological challenges, and each drilling project or expedition must make a series of choices to address these challenges. We report on the workflow for sampling hard rock cores for microbiological and biogeochemical research that was developed and optimized during International Ocean Discovery Program (IODP) Expedition 399. All steps of the workflow, including selection of the sample and its shipboard homogenization and subsampling for specific analyses, were designed to maximize the potential for interdisciplinary collaborations and syntheses of results. Furthermore, multiple strategies to minimize and detect potential microbial …