Digital Commons Network^™

Implementation Of A Prediabetes Decision Aid In Primary Care, Lindsay Kim Md, Beth Careyva M.D., Autumn Kieber-Emmons Md, Mph, Nicole M. Burgess Bs, Roya Hamadani Mph, Aashka Patel

USF-LVHN SELECT

No abstract provided.

Process Improvements For The Treatment Of Iron Deficiency Anemia In Pregnancy, Iris Kong Md, Natalie Chlus Md, Bradley Lash Md

USF-LVHN SELECT

No abstract provided.

Effect Of Sex On The Development Of Non-Alcoholic Fatty Liver Disease During The Progression Of Metabolic Syndrome, Noah C. Wallace

Electronic Theses and Dissertations Archive

Background: There is an association between sex and the prevalence of Metabolic Syndrome (MetS) and Non-Alcoholic Fatty Liver Disease (NAFLD). Objective: Determine the effects of sex and high fat/sucrose diet on the development of MetS and NAFLD. Methods: 30 male and 30 female C57BL/6 mice were place on one of three diets: High Fat (45% Fat), High Sugar (60% Sucrose), and Control. Results: Male mice on a High Fat diet showed the greatest weight gain amongst all the group as well as demonstrating earlier signs of glucose intolerance. Only those placed on a high sugar diet had indications of liver …

The Effect Of Mitochondrial Transplant Therapy On Muscle Damage And Exercise Performance, Samantha Lynn Davis

Electronic Theses and Dissertations Archive

Objective: To determine if weekly mitochondrial transplants given to animals undergoing a muscle damaging protocol will improve exercise performance and immune responses. Methods: Mitochondrial injections were given to eight-week-old C57/BL6 mice (N=7/group) for 6 weeks under a muscle damaging exercise protocol. A run-to-fatigue test was completed at baseline, 4, and 6 weeks. Blood was collected immediately after the last run; tissues and organs were harvested 24 hours later for transcription measurements and histology. Results: No significant differences were found in exercise performance in any week. Histological analysis did not show any differences between groups. PGC1-α transcripts were significantly decreased in …

Mitochondrial Involvement In Sarcopenia, Charles Affourtit, Jane E. Carré

School of Biomedical Sciences

Sarcopenia lowers the quality-of-life for millions of people across the world, as accelerated loss of skeletal muscle mass and function contributes to both age- and disease-related frailty. Physical activity remains the only proven therapy for sarcopenia to date, but alternatives are much sought after to manage this progressive muscle disorder in individuals who are unable to exercise. Mitochondria have been widely implicated in the etiology of sarcopenia and are increasingly suggested as attractive therapeutic targets to help restore the perturbed balance between protein synthesis and breakdown that underpins skeletal muscle atrophy. Reviewing current literature, we note that mitochondrial bioenergetic changes …

Ketamine For Pain In Sickle Cell Disease Reduces Opioid Usage, Christina O Onyebuchi, Corrie E Chumpitazi, Jennifer L Placencia, Andrea N Jackson, Jennifer L Jones, Laura Torres, Venée N Tubman

Faculty, Staff and Students Publications

CONTEXT: Pain attributable to sickle cell disease (SCD) is often unpredictable, recurrent, and requires complex treatments. Subanesthetic ketamine infusion has been studied in other diseases and disorders, but there is still limited data on its efficacy in pain management for SCD.

OBJECTIVES: The primary objective is to determine if subanesthetic ketamine infusion reduces pain scores and opioid requirements in hospitalized pediatric patients with SCD.

RESULTS: Forty-six admissions among 22 patients between February 2018 and December 2019 were analyzed. We observed decrease in pain scores within 24 hours of ketamine initiation in 34 of 46 admissions (mean pain score per patient …

Worldwide Trends In Underweight And Obesity From 1990 To 2022: A Pooled Analysis Of 3663 Population- Representative Studies With 222 Million Children, Adolescents, And Adults, Ncd Risk Factor Collaboration (Ncd-Risc), Nowell H. Phelps, Rosie K . Singleton, Bin Zhou, Rachel A. Heap, Anu Mishra, James E. Bennett, Christopher J. Paciorek, Gladys Maestre, Jesus Melgarejo

School of Medicine Publications

Background: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.

Methods: We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5-19 years), …

Diabetes Study Of Children Of Diverse Ethnicity And Race: Study Design, Maria J Redondo, Kylie K Harrall, Deborah H Glueck, Mustafa Tosur, Serife Uysal, Andrew Muir, Elizabeth G Atkinson, Melanie R Shapiro, Liping Yu, William E Winter, Michael Weedon, Todd M Brusko, Richard Oram, Kendra Vehik, William Hagopian, Mark A Atkinson, Dana Dabelea, Discover Study Group

Faculty, Staff and Students Publications

AIMS: Determining diabetes type in children has become increasingly difficult due to an overlap in typical characteristics between type 1 diabetes (T1D) and type 2 diabetes (T2D). The Diabetes Study in Children of Diverse Ethnicity and Race (DISCOVER) programme is a National Institutes of Health (NIH)-supported multicenter, prospective, observational study that enrols children and adolescents with non-secondary diabetes. The primary aim of the study was to develop improved models to differentiate between T1D and T2D in diverse youth.

MATERIALS AND METHODS: The proposed models will evaluate the utility of three existing T1D genetic risk scores in combination with data on …

Assessment Of The Impact Of Humic Acids On Intestinal Microbiota, Gut Integrity, Ileum Morphometry, And Cellular Immunity Of Turkey Poults Fed An Aflatoxin B1-Contaminated Diet, Jesus A. Maguey-Gonzalez, Jing Liu, Guolong Zhang, Juan D. Latorre, Juan O. Hernandez-Ramirez, Maria De Jesus Nava-Ramirez, Roberto Señas-Cuesta, Sergio Gomez-Rosales, Maria De Lourdes Angeles, Andressa Stein, Bruno Solis-Cruz, Daniel Hernandez-Patlan, Ruben Merino-Guzman, Xochitl Hernandez-Velasco, Inkar Castellanos-Huerta, Santiago Uribe-Diaz, Alma Vazquez-Duran, Abraham Mendez-Albores, Victor Petrone-Garcia, Guillermo Tellez Jr., Billy M. Hargis, Guillermo Tellez-Isaias

Poultry Science Faculty Publications and Presentations

A recent study published data on the growth performance, relative weights of the organs of the gastrointestinal tract, liver histology, serum biochemistry, and hematological parameters for turkey poults fed an experimental diet contaminated with aflatoxin B₁ (AFB₁) and humic acids (HA) extracted from vermicompost. The negative effects of AFB₁ (250 ng AFB₁/g of feed) were significantly reduced by HA supplementation (0.25% w/w), suggesting that HA might be utilized to ameliorate the negative impact of AFB₁ from contaminated diets. The present study shows the results of the remaining variables, as an extension of …

Fatty Acids And Their Proteins In Adipose Tissue Inflammation, Rahul Mallick, Sanjay Basak, Ranjit Kumar Das, Antara Banerjee, Sujay Paul, Surajit Pathak, Asim K. Duttaroy

Health & Biomedical Sciences Faculty Publications

Chronic low-grade adipose tissue inflammation is associated with metabolic disorders. Inflammation results from the intertwined cross-talks of pro-inflammatory and anti-inflammatory pathways in the immune response of adipose tissue. In addition, adipose FABP4 levels and lipid droplet proteins are involved in systemic and tissue inflammation. Dysregulated adipocytes help infiltrate immune cells derived from bone marrow responsible for producing cytokines and chemokines. When adipose tissue expands in excess, adipocyte exhibits increased secretion of adipokines and is implicated in metabolic disturbances due to the release of free fatty acids. This review presents an emerging concept in adipose tissue fat metabolism, fatty acid handling …

Effect Of Heat Stress On The Hypothalamic Expression Profile Of Water Homeostasis-Associated Genes In Low- And High-Water Efficient Chicken Lines, Loujain Aloui, Elizabeth S. Greene, Travis Tabler, Kentu Lassiter, Kevin Thompson, Walter G. Bottje, Sara Orlowski, Sami Dridi

Poultry Science Faculty Publications and Presentations

With climate change, selection for water efficiency and heat resilience are vitally important. We undertook this study to determine the effect of chronic cyclic heat stress (HS) on the hypothalamic expression profile of water homeostasis-associated markers in high (HWE)- and low (LWE)-water efficient chicken lines. HS significantly elevated core body temperatures of both lines. However, the amplitude was higher by 0.5–1°C in HWE compared to their LWE counterparts. HWE line drank significantly less water than LWE during both thermoneutral (TN) and HS conditions, and HS increased water intake in both lines with pronounced magnitude in LWE birds. HWE had better …

Effect Of A Microencapsulated Phyto/Phycogenic Blend Supplementation On Growth Performance, Processing Parameters, Meat Quality, And Sensory Profile In Male Broilers, Garrett J. Mullenix, Elizabeth S. Greene, Alison Ramser, Clay Maynard, Sami Dridi

Poultry Science Faculty Publications and Presentations

Powered by consumer taste, value, and preferences, natural products including phytogenics and algae are increasingly and separately used in the food systems where they have been reported to improve growth performance in poultry and livestock. The present study aimed to determine the effects of a new feed additive, microencapsulated NUQO© NEX, which contains a combination of phytogenic and phycogenic, on broiler growth performance, blood chemistry, bone health, meat quality and sensory profile. Male Cobb500 chicks (n = 1,197) were fed a 3-phase feeding intervals; 1–14d starter, 15–28d grower, and 29–40d finisher. The dietary treatments included a corn-soy basal Control …

Novel 4th-Generation Phytase Improves Broiler Growth Performance And Reduces Woody Breast Severity Through Modulation Of Muscle Glucose Uptake And Metabolism, Carrie L. Walk, Garrett J. Mullenix, Craig W. Maynard, Elizabeth S. Greene, Clay Maynard, Nelson Ward, Sami Dridi

Poultry Science Faculty Publications and Presentations

The objective of the present study was to determine the effect of a novel (4th generation) phytase supplementation as well as its mode of action on growth, meat quality, and incidence of muscle myopathies. One-day old male broilers (n = 720) were weighed and randomly allocated to 30 floor pens (24 birds/pen) with 10 replicate pens per treatment. Three diets were fed from hatch to 56- days-old: a 3-phase corn-soy based diet as a positive control (PC); a negative control (NC) formulated to be isocaloric and isonitrogenous to the PC and with a reduction in Ca and available P, …

Ellagic Acid Inhibits Α-Synuclein Propagation And Alleviates The Neurotoxicity By Enhancing Autophagic Flux In Animal Model Of Parkinson’S Disease, Nada Akram Abdellatif

Theses

Parkinson’s Disease (PD) is the second most common neurological disorder pathologically characterized by loss of dopaminergic neurons in the Substantia Nigra pars compacta (SNc) as well as the formation of Lewy bodies composed mainly of α-synuclein (α-syn) aggregates. It has been documented that abnormal aggregation of α-syn is one of the major causes of developing PD. Ellagic Acid (EA) is a widely known dietary supplement found in pomegranates as well as a plethora of berries and nuts. EA has been shown to prevent α-syn aggregates’ toxicity in cellular model of PD. In the current study we aim to evaluate whether …

Reproductive Biology Of The Jellyfish Outbreak Along The Uae Coastal Waters, Amrutha Aravind

Dissertations

Jellyfish are a ubiquitous occurrence in the world’s oceans. During the past decades, dramatic spatial increases and temporal shifts in jellyfish distributions have been reported around the world. The United Arab Emirates (UAE) coastal area also has experienced several blooms along with severe adverse impacts on its economic facilities. Few studies have been conducted within the Arabian Gulf and the Sea of Oman, to identify the blooming species and the environmental parameters that favor such breakouts. The present study aimed to identify the jellyfish species found along the coastal area of UAE and trying to link their occurrence with seasonal …

Barring Judicial Review, Laura E. Dolbow

Vanderbilt Law Review

Whether judicial review is available is one of the most hotly contested issues in administrative law. Recently, laws that prohibit judicial review have sparked debate in the Medicare, immigration, and patent contexts. These debates are continuing in challenges to the recently created Medicare price negotiation program. Yet despite debates about the removal of judicial review, little is known about how often, and in what contexts, Congress has expressly precluded review. This Article provides new insights about express preclusion by conducting an empirical study of the U.S. Code. It creates an original dataset of laws that expressly preclude judicial review of …

Weed Detection Using Lightweight Deep Learning Models With Transfer Learning And Hyperparameter Optimization, Ali Shaheen

Masters Theses & Doctoral Dissertations

In agriculture, the presence of weeds adversely impacts yield. Confronting this challenge manually requires continuous and labor-intensive field monitoring processes. Artificial intelligence, notably deep learning is one the most promising for weed detection, particularly when deployed to edge devices. However, these edge devices have limited computational resources, making it challenging to deploy large Deep Learning (DL) models often resulting in a performance-size trade-off. This research proposes a three-pronged approach that leverages DL lightweight architectures (LWA) to optimize for size and minimize computational resources at the edge, transfer learning to mitigate constraints associated with limited data commonly encountered in this domain, …

The Association Between Diet Quality And Glycemic Outcomes Among People With Type 1 Diabetes., Melanie B. Gillingham, Martin Chase Marak, Michael C. Riddell, Peter Calhoun, Robin L. Gal, Susana R. Patton, Peter G. Jacobs, Jessica R. Castle, Mark A. Clements, Francis J. Doyle, Michael R. Rickels, Corby K. Martin

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: The amount and type of food consumed impacts the glycemic response and insulin needs of people with type 1 diabetes mellitus (T1DM). Daily variability in consumption, reflected in diet quality, may acutely impact glycemic levels and insulin needs.

OBJECTIVE: Type 1 Diabetes Exercise Initiative (T1DEXI) data were examined to evaluate the impact of daily diet quality on near-term glycemic control and interaction with exercise.

METHODS: Using the Remote Food Photography Method, ≤8 d of dietary intake data were analyzed per participant. Diet quality was quantified with the Healthy Eating Index-2015 (HEI), where a score of 100 indicates the highest-quality …

The Application Of Digital Frailty Screening To Triage Nonhealing And Complex Wounds, Ram Kinker Mishra, Rasha O Bara, Alejandro Zulbaran-Rojas, Catherine Park, Malindu E Fernando, Jeffrey Ross, Brian Lepow, Bijan Najafi

Center on Aging Staff Publications

Objective: We investigated the association between the complexity of diabetic foot ulcers (DFUs) and frailty.

Research design and methods: Individuals (n = 38) with Grade 2 Wagner DFU were classified into 3 groups based on the Society for Vascular Surgery risk-stratification for major limb amputation as Stage 1 at very low risk (n = 19), Stage 2 at low risk (n = 9), and Stage 3 to 4 at moderate-to-high risk (n = 10) of major limb amputation. Frailty status was objectively assessed using a validated digital frailty meter (FM). The FM works by quantifying weakness, slowness, rigidity, and exhaustion …

A Study Of Dietary Patterns Derived By Cluster Analysis And Their Association With Metabolic Dysfunction-Associated Steatotic Liver Disease Severity Among Hispanic Patients, Xiaotao Zhang, Carrie R Daniel, Valeria Soltero, Ximena Vargas, Shilpa Jain, Fasiha Kanwal, Aaron P Thrift, Maya Balakrishnan

Faculty, Staff and Student Publications

Introduction: Diet is a modifiable metabolic dysfunction-associated steatotic liver disease (MASLD) risk factor, but few studies have been conducted among Hispanic patients, despite the fact that MASLD prevalence and severity are highest among this ethnic subgroup. We aimed to identify prevalent dietary patterns among Hispanic patients using cluster analysis and to investigate associations with MASLD severity.

Methods: This cross-sectional analysis included 421 Harris County MASLD Cohort participants who self-reported Hispanic ethnicity and completed baseline food frequency questionnaires. All included patients had MASLD, diagnosed per standard clinical criteria. K-means analysis was used to identify clusters of patients sharing similar dietary habits. …

Psychosocial Moderators Of Polygenic Risk Scores Of Inflammatory Biomarkers In Relation To Grimage, Amanda J F Tamman, Dora Koller, Sheila Nagamatsu, Brenda Cabrera-Mendoza, Chadi Abdallah, John H Krystal, Joel Gelernter, Janitza L Montalvo-Ortiz, Renato Polimanti, Robert H Pietrzak

Faculty, Staff and Students Publications

GrimAge acceleration has previously predicted age-related morbidities and mortality. In the current study, we sought to examine how GrimAge is associated with genetic predisposition for systemic inflammation and whether psychosocial factors moderate this association. Military veterans from the National Health and Resilience in Veterans study, which surveyed a nationally representative sample of European American male veterans, provided saliva samples for genotyping (N = 1135). We derived polygenic risk scores (PRS) from the UK Biobank as markers of genetic predisposition to inflammation. Results revealed that PRS for three inflammatory PRS markers—HDL (lower), apolipoprotein B (lower), and gamma-glutamyl transferase (higher)—were associated …

Targeting Glutamine Dependence With Drp-104 Inhibits Proliferation And Tumor Growth Of Castration-Resistant Prostate Cancer, David Moon, J Spencer Hauck, Xue Jiang, Holly Quang, Lingfan Xu, Fan Zhang, Xia Gao, Robert Wild, Jeffrey I Everitt, Everardo Macias, Yiping He, Jiaoti Huang

Faculty, Staff and Students Publications

BACKGROUND: Prostate cancer (PCa) continues to be one of the leading causes of cancer deaths in men. While androgen deprivation therapy is initially effective, castration-resistant PCa (CRPC) often recurs and has limited treatment options. Our previous study identified glutamine metabolism to be critical for CRPC growth. The glutamine antagonist 6-diazo-5-oxo-l-norleucine (DON) blocks both carbon and nitrogen pathways but has dose-limiting toxicity. The prodrug DRP-104 is expected to be preferentially converted to DON in tumor cells to inhibit glutamine utilization with minimal toxicity. However, CRPC cells' susceptibility to DRP-104 remains unclear.

METHODS: Human PCa cell lines (LNCaP, LAPC4, C4-2/MDVR, PC-3, 22RV1, …

In Citizenship We Trust? The Citizenship Question Need Not Impede Puerto Rican Decolonization, Jimmy Mcdonough

Michigan Law Review

Puerto Rico is an uncomfortable reminder of the democratic deficits within the world’s oldest constitutional democracy. Puerto Ricans are U.S. citizens who live in a U.S. territory that is subject to the plenary authority of Congress, to which they cannot elect voting members. In 2022, under unified Democratic control for the first time in a decade, Congress considered the Puerto Rico Status Act, legislation that would finally decolonize Puerto Rico. The Status Act offered Puerto Rican voters three alternatives to the colonial status quo—statehood, independence, or sovereignty in free association—and committed Congress to implementing whichever alternative won majority support from …

The Conceptual Definition Of Sarcopenia: Delphi Consensus From The Global Leadership Initiative In Sarcopenia (Glis), Ben Kirk, Ellen F Binder, Et Al.

2020-Current year OA Pubs

IMPORTANCE: Sarcopenia, the age-related loss of muscle mass and strength/function, is an important clinical condition. However, no international consensus on the definition exists.

OBJECTIVE: The Global Leadership Initiative in Sarcopenia (GLIS) aimed to address this by establishing the global conceptual definition of sarcopenia.

DESIGN: The GLIS steering committee was formed in 2019-21 with representatives from all relevant scientific societies worldwide. During this time, the steering committee developed a set of statements on the topic and invited members from these societies to participate in a two-phase International Delphi Study. Between 2022 and 2023, participants ranked their agreement with a set of …

March 2024 News, Office Of Sustainability

Office of Sustainability Newsletter

No abstract provided.

Trans-Disciplinary Communication In Collaborative Co-Design For Knowledge Sharing, James Lipuma, Cristo León

STEM for Success Resources

Explore the transformative power of Trans-Disciplinary Communication in Collaborative Co-Design for effective knowledge sharing.

Rights
All content in this magazine is licensed under a Creative Commons Attribution License. Attribution-Non-Commercial-Non-Derivatives 4.0 International (CC BY-NC-ND 4.0).

Becoming And Acting As An Ally Against Weight-Based Discrimination, Christopher J. Waterbury, Larry R. Martinez, Liana Bernard, Nicholas A. Smith

Psychology Faculty Publications and Presentations

We appreciate and agree with the importance of the Best Practices for Weight at Work Research outlined by Lemmon et al. (Reference Lemmon, Jensen and Kuljanin2023). To help further contribute to this body of literature, we connect the scholarship related to weight-basedFootnote1 discrimination to contemporary allyship scholarship. Allyship support and advocacy behaviors improve employee experiences on day-to-day and long-term bases, and are therefore critical to research about weight at work. It is critically important to examine the development of allies against weight-stigma for two reasons.

Evaluation Of The Heal™Ing Mental Health Program: A Prospective Cohort Study Of Short-Term Changes From A Physical Activity And Lifestyle Education Program For People With Mental Health Disorders Living In Rural Australia, Annette J. Raynor, Sophia Nimphius, Daniel Kadlec, Sally Casson, Caitlin Fox-Harding, Lauren V. Fortington

Research outputs 2022 to 2026

This study aimed to evaluate short-term outcomes of the HEAL™ing Mental Health program, an 8-week intervention for change in functional, behavioural and physiological health and wellbeing designed for people living with mental health conditions in rural or regional areas of Australia. A prospective cohort study was completed, reporting on 19 items (pre-program) and 15 (post-participation change), organised across seven domains. Participants took part in an Accredited Exercise Physiologist/Nurse led supervised group exercise (60 minutes) and healthy lifestyle education program (60 minutes). Separate linear mixed models with restricted maximum likelihood were used to examine the primary research question considering the effect …

Feeding Behavior Of Sweet Potato Weevil, Cylas Formicarius (Fabricius) (Coleoptera: Brentidae) On Three Sweet Potato, Ipomoea Batatas L. Cultivars Grown In Tarlac, Philippines, Jerah Mystica Novenario, Flor Ceballo-Alcantara

The Philippine Agricultural Scientist

Sweet potato is grown in tropical countries for its edible tubers, which have become an essential food source. It is usually propagated through vine-cutting, which can be obtained from harvested plants or nurseries intended for cutting production only. The recurrent use of vines may cause increased weevil infestation. The crop is known to be infested with insect pests. More importantly, the sweet potato weevil, Cylas formicarius, targets the tubers, thus, causing the economic losses. Sweet potato farmers in Tarlac claim that only one sweet potato cultivar is being attacked by C. formicarius, however, it was found in this experiment that …

Does Watching Tv Or Videos During The Day Affect Nighttime Urination?

Saudi Medical Journal

No abstract provided.