Digital Commons Network^™

Does Watching Tv Or Videos During The Day Affect Nighttime Urination?

Saudi Medical Journal

No abstract provided.

Environmental Justice: A Missing Core Tenet Of Global Health, Redeat Workneh, Merhawit Abadi, Krystle Perez, Sharla Rent, Elliott Mark Weiss, Stephanie Kukora, Olivia Brandon, Gal Barbut, Sahar Rahiem, Shaphil Wallie, Joseph Mhango, Benjamin C Shayo, Friday Saidi, Gesit Metaferia, Mahlet Abayneh, Gregory C Valentine

Faculty, Staff and Students Publications

No abstract provided.

Heterozygous Map3k20 Variants Cause Ectodermal Dysplasia, Craniosynostosis, Sensorineural Hearing Loss, And Limb Anomalies, Daniel Brooks, Elizabeth Burke, Sukyeong Lee, Tanya N Eble, Melanie O'Leary, Ikeoluwa Osei-Owusu, Heidi L Rehm, Shweta U Dhar, Lisa Emrick, David Bick, Michelle Nehrebecky, Ellen Macnamara, Dídac Casas-Alba, Judith Armstrong, Carolina Prat, Antonio F Martínez-Monseny, Francesc Palau, Pengfei Liu, David Adams, Undiagnosed Diseases Network, Seema Lalani, Jill A Rosenfeld, Lindsay C Burrage

Faculty, Staff and Students Publications

Biallelic pathogenic variants in MAP3K20, which encodes a mitogen-activated protein kinase, are a rare cause of split-hand foot malformation (SHFM), hearing loss, and nail abnormalities or congenital myopathy. However, heterozygous variants in this gene have not been definitively associated with a phenotype. Here, we describe the phenotypic spectrum associated with heterozygous de novo variants in the linker region between the kinase domain and leucine zipper domain of MAP3K20. We report five individuals with diverse clinical features, including craniosynostosis, limb anomalies, sensorineural hearing loss, and ectodermal dysplasia-like phenotypes who have heterozygous de novo variants in this specific region of the gene. …

Increased Plasma Branched Short-Chain Fatty Acids And Improved Glucose Homeostasis: The Microbiome And Insulin Longitudinal Evaluation Study (Miles), Arianne Aslamy, Alexis C Wood, Elizabeth T Jensen, Alain G Bertoni, Patricia A Sheridan, Kari E Wong, Gautam Ramesh, Jerome I Rotter, Yii-Der I Chen, Mark O Goodarzi

Faculty, Staff and Students Publications

Short-chain fatty acids (SCFAs) have been extensively studied for potential beneficial roles in glucose homeostasis and risk of diabetes; however, most of this research has focused on butyrate, acetate, and propionate. The effect on metabolism of branched SCFAs (BSCFAs; isobutyrate, isovalerate, and methylbutyrate) is largely unknown. In a cohort of 219 non-Hispanic White participants and 126 African American participants, we examined the association of BSCFA with dysglycemia (prediabetes and diabetes) and oral glucose tolerance test-based measures of glucose and insulin homeostasis, as well as with demographic, anthropometric, lifestyle, and lipid traits, and other SCFAs. We observed a bimodal distribution of …

Health-Promoting Benefits Of Lentils: Anti-Inflammatory And Anti-Microbial Effects, Rachel Alexander, Abdullah Khaja, Nicholas Debiec, Alex Fazioli, Mary Torrance, Mohammed S. Razzaque

School of Medicine Publications

This paper describes how lentils (Lens culinaris species) can positively affect health by reducing inflammation, providing antioxidants, and displaying antimicrobial properties. Lentils are rich in proteins, essential amino acids, minerals, and fibers, making them a valuable source of nutrition, particularly in low and middle-income countries. Lentils have many health benefits, including positive effects on diabetes management, support for cardiovascular health, and antioxidative properties. The antioxidative properties of lentils, attributed to their phenolic content, and their ability to inhibit inflammation-related enzymes are also discussed. We discuss the potential of lentils as a dietary tool in promoting immunity, reducing disease burdens, …

Oblique Anterior Column Realignment With A Mini-Open Posterior Column Osteotomy For Minimally Invasive Adult Spinal Deformity Correction: Illustrative Case, Zach Pennington, Nolan J. Brown, Seyedamirhossein Pishva, Hernán F.J. González, Martin H. Pham

Student Publications

BACKGROUND Adult spinal deformity (ASD) occurs from progressive anterior column collapse due to disc space desiccation, compression fractures, and autofusion across disc spaces. Anterior column realignment (ACR) is increasingly recognized as a powerful tool to address ASD by progressively lengthening the anterior column through the release of the anterior longitudinal ligament during lateral interbody approaches. Here, we describe the application of minimally invasive ACR through an oblique antepsoas corridor for deformity correction in a patient with adult degenerative scoliosis and significant sagittal imbalance.

OBSERVATIONS A 65-year-old female with a prior history of L4–5 transforaminal lumbar interbody fusion and morbid obesity …

Failure Rate Of Anti-Tumor Necrosis Factor Α Biologics In Very Early Onset Inflammatory Bowel Disease, Ashleigh Watson, Lina B Karam, Richard Kellermayer

Faculty, Staff and Students Publications

No abstract provided.

Echocardiographic Image Collection And Evaluation In Infants With Chd: Lessons Learned From The Imaging Core Lab For The Residual Lesion Score Study, Jami C Levine, Steven Colan, Felicia Trachtenberg, Edward Marcus, Matthew Ferguson, Anitha Parthiban, Carolyn Taylor, Andreea Dragulescu, Benjamin Goot, Ronald V Lacro, Carol Mcfarland, Shanthi Narasimhan, Matthew O'Connor, Marcus Schamberger, Shubhika Srivistava, Michael Taylor, Meena Nathan

Faculty, Staff and Students Publications

Many factors affect patient outcome after congenital heart surgery, including the complexity of the heart disease, pre-operative status, patient specific factors (prematurity, nutritional status and/or presence of comorbid conditions or genetic syndromes), and post-operative residual lesions. The Residual Lesion Score is a novel tool for assessing whether specific residual cardiac lesions after surgery have a measurable impact on outcome. The goal is to understand which residual lesions can be tolerated and which should be addressed prior to leaving the operating room. The Residual Lesion Score study is a large multicentre prospective study designed to evaluate the association of Residual Lesion …

Contemplating On The End Of Integrated Care-Part Ii: Living The Questions To Foster Adaptability, Deepu George, Parinda Khatri

School of Medicine Publications

This article extends the use of the ecocycle planning framework to describe challenges ahead for the integrated care and Collaborative Family Healthcare Association (CFHA). The authors make the case that to remain agile and adaptable, there are contextual, ecological, and moral challenges that integrated care and CFHA should keep in the forefront as they navigate the future of an inequitable health care system that is morphing at a rapid pace. These influences include but are not limited to challenges of social determinants of health, artificial intelligence, generational differences in technology among older and younger populations, the moral issue of poverty, …

Case Of Nocturnal Emesis, Weight Loss, And Aspiration Pneumonia, Roman Babayev, Sharonda Taylor, Elizabeth V Franklin

Faculty, Staff and Students Publications

No abstract provided.

Advances In Pediatric Acute Kidney Injury Pharmacology And Nutrition: A Report From The 26th Acute Disease Quality Initiative (Adqi) Consensus Conference, Molly Wong Vega, Michelle C Starr, Patrick D Brophy, Prasad Devarajan, Danielle E Soranno, Ayse Akcan-Arikan, Rajit Basu, Stuart L Goldstein, Jennifer R Charlton, Erin Barreto

Faculty, Staff and Students Publications

BACKGROUND: In the past decade, there have been substantial advances in our understanding of pediatric AKI. Despite this progress, large gaps remain in our understanding of pharmacology and nutritional therapy in pediatric AKI.

METHODS: During the 26th Acute Disease Quality Initiative (ADQI) Consensus Conference, a multidisciplinary group of experts reviewed the evidence and used a modified Delphi process to achieve consensus on recommendations for gaps and advances in care for pharmacologic and nutritional management of pediatric AKI. The current evidence as well as gaps and opportunities were discussed, and recommendations were summarized.

RESULTS: Two consensus statements were developed. (1) High-value, …

Familial Hypercholesterolemia Variant And Cardiovascular Risk In Individuals With Elevated Cholesterol, Yiyi Zhang, Jacqueline S Dron, Brandon K Bellows, Amit V Khera, Junxiu Liu, Pallavi P Balte, Elizabeth C Oelsner, Sami Samir Amr, Matthew S Lebo, Anna Nagy, Gina M Peloso, Pradeep Natarajan, Jerome I Rotter, Cristen Willer, Eric Boerwinkle, Christie M Ballantyne, Pamela L Lutsey, Myriam Fornage, Donald M Lloyd-Jones, Lifang Hou, Bruce M Psaty, Joshua C Bis, James S Floyd, Ramachandran S Vasan, Nancy L Heard-Costa, April P Carson, Michael E Hall, Stephen S Rich, Xiuqing Guo, Dhruv S Kazi, Sarah D De Ferranti, Andrew E Moran

Faculty, Staff and Student Publications

IMPORTANCE: Familial hypercholesterolemia (FH) is a genetic disorder that often results in severely high low-density lipoprotein cholesterol (LDL-C) and high risk of premature coronary heart disease (CHD). However, the impact of FH variants on CHD risk among individuals with moderately elevated LDL-C is not well quantified.

OBJECTIVE: To assess CHD risk associated with FH variants among individuals with moderately (130-189 mg/dL) and severely (≥190 mg/dL) elevated LDL-C and to quantify excess CHD deaths attributable to FH variants in US adults.

DESIGN, SETTING, AND PARTICIPANTS: A total of 21 426 individuals without preexisting CHD from 6 US cohort studies (Atherosclerosis Risk …

Single Domain Soft Ferromagnetic Ferrofluid Suitable For Intratumoural Magnetic Hyperthermia, Karthickraja Duraisamy, Muthu Devaraj, Ajithkumar Gangadharan, Karen S. Martirosyan, Niroj Kumar Sahu, Prasath Manogaran, Girija Easwaradas Kreedapathy

Physics & Astronomy Faculty Publications

Magnetic hyperthermia is an effective modality for treating cancerous cells selectively at the intracellular level via proper administration, surface tagging and appropriate choice of magnetic nanoparticle. Also, achieving the therapeutic temperature with as much low concentration of nanoparticles, as possible, is desirable. Recently, ferromagnetic nanoparticles or ferrofluid are gaining attention as effective magnetic hyperthermia agents due to their enhanced heating potential under in vivo conditions. In the present work, we have fabricated citrate capped cobalt ferrite ferrofluid via a simple two-step process and investigated the physicochemical, magnetic and induction heating performance. The average size of the synthesized nanoparticle …

Relationships Between Physical Behaviour Phenotypes Of Mothers In Pregnancy And Their Offspring With Child Body Composition, Erin Howie, Alexander Nelson, Joanna A. Mcveigh, Aline Andres

Health, Human Performance and Recreation Faculty Publications and Presentations

Aim

The aim of this study was to identify physical behaviour phenotypes in mothers in the first trimester and in their offspring at 24 months of age. The secondary aim was to examine relationships between mother and child behaviours with child body composition at age 24 months.

Methods

Longitudinal secondary analysis of the Glowing cohort collected between 1 February 2011 and 22 August 2017 in Little Rock, Arkansas. Behaviours were measured using ankle-worn accelerometers in mothers during the first trimester and offspring at 24 months of age, including total activity, sleep, sedentary time and a novel variable of daily variation, …

Evidencing Occupational Therapy In Primary Care, Mary Hickson, Miranda Cunningham, Sam Wakley, Alison Warren, Avril Collinson

School of Health Professions

A group of lecturers and researchers, from occupational therapyand dietetics, look at the evidence base for the effectiveness ofoccupational therapy interventions in primary care. They arguethat this is in its infancy and call for further service evaluation andresearch.

Navigating The Complexity Of Applying Nutrition Evidence To Individualised Care: Summary Of An Academy Of Nutrition Sciences Position Paper, Judith Buttriss, Mary Hickson, Kevin Whelan, Christine Williams

School of Health Professions

No abstract provided.

Metatranscriptomics Reveals Diversity Of Symbiotic Interaction And Mechanisms Of Carbon Exchange In The Marine Cyanolichen Lichina Pygmaea, Nathan Chrismas, B Tindall‐Jones, Helen Jenkins, Joanna Harley, Kimberley Bird, Michael Cunliffe

School of Biological and Marine Sciences

Lichens are exemplar symbioses based upon carbon exchange between photobionts and their mycobiont hosts. Historically considered a two-way relationship, some lichen symbioses have been shown to contain multiple photobiont partners; however, the way in which these photobiont communities react to environmental change is poorly understood. Lichina pygmaea is a marine cyanolichen that inhabits rocky seashores where it is submerged in seawater during every tidal cycle. Recent work has indicated that L. pygmaea has a complex photobiont community including the cyanobionts Rivularia and Pleurocapsa. We performed rRNA-based metabarcoding and mRNA metatranscriptomics of the L. pygmaea holobiont at high and low tide …

Biomarker-Directed Targeted Therapy Plus Durvalumab In Advanced Non-Small-Cell Lung Cancer: A Phase 2 Umbrella Trial, Benjamin Besse, Daniel Morgensztern, Et Al.

2020-Current year OA Pubs

For patients with non-small-cell lung cancer (NSCLC) tumors without currently targetable molecular alterations, standard-of-care treatment is immunotherapy with anti-PD-(L)1 checkpoint inhibitors, alone or with platinum-doublet therapy. However, not all patients derive durable benefit and resistance to immune checkpoint blockade is common. Understanding mechanisms of resistance-which can include defects in DNA damage response and repair pathways, alterations or functional mutations in STK11/LKB1, alterations in antigen-presentation pathways, and immunosuppressive cellular subsets within the tumor microenvironment-and developing effective therapies to overcome them, remains an unmet need. Here the phase 2 umbrella HUDSON study evaluated rational combination regimens for advanced NSCLC following failure of …

Scoring System For Prediction Of Overall Survival In Patients With Renal Cell Carcinoma T3an0m0, Caio Vinícius Suartz, Maurício Dener Cordeiro, Paulo Afonso De Carvalho, Fábio Pescarmona Gallucci, Leopoldo Alves Ribeiro-Filho, Leonardo Cardili, Arjun Sivaraman, François Audenet, José Mauricio Mota, William Carlos Nahas

2020-Current year OA Pubs

OBJECTIVE: We aim to create a new score to predict postoperative overall survival in patients with nonmetastatic T3aN0 renal cell carcinoma.

METHODS: We reviewed the clinical data of adult patients who underwent radical nephrectomy for renal cell carcinoma between December 2007 and January 2022 in a single tertiary oncological institution. Clinical characteristics, clinical-pathological staging and histopathological characteristics were analysed. Survival analyses were determined using the Kaplan-Meier curve. A nomogram was established using Cox proportional hazard regression to identify the prognostic factors affecting the overall survival. The area under the curve, calibration curves and decision curve analysis were used to evaluate …

Altered Larval Activation Response Associated With Multidrug Resistance In The Canine Hookworm Ancylostoma Caninum, Elise L Mckean, Emilia Grill, Young-Jun Choi, Makedonka Mitreva, Damien M O'Halloran, John M Hawdon

2020-Current year OA Pubs

Parasitic gastrointestinal nematodes pose significant health risks to humans, livestock, and companion animals, and their control relies heavily on the use of anthelmintic drugs. Overuse of these drugs has led to the emergence of resistant nematode populations. Herein, a naturally occurring isolate (referred to as BCR) of the dog hookworm,

Frequency Of Treatment Failure Of Utis In Children With Congenital Urinary Tract Anomalies, Catherine S Forster, Alexis C Wood, Stephanie Davis-Rodriguez, Pearl W Chang, Sanyukta Desai, Michael Tchou, John M Morrison, Jamie D Mudd, Brittany D Casey, Victor Trevisanut, Rana F Hamdy, Vijaya Vemulakonda, Patrick W Brady, Sowdhamini S Wallace, Uti In Children With Cakut Study Group

Faculty, Staff and Students Publications

OBJECTIVES: Children with certain congenital anomalies of the kidney and urinary tract and neurogenic bladder (CAKUT/NGB) are at higher risk of treatment failure for urinary tract infections (UTIs) than children with normal genitourinary anatomy, but the literature describing treatment and outcomes is limited. The objectives of this study were to describe the rate of treatment failure in children with CAKUT/NGB and compare duration of antibiotics between those with and without treatment failure.

METHODS: Multicenter retrospective cohort of children 0 to 17 years old with CAKUT/NGB who presented to the emergency department with fever or hypothermia and were diagnosed with UTI …

Communities Of Practice To Facilitate Change In Health Professions Education: A Realist Synthesis, Gemma Jenkins, Claire Palermo, Alexander M. Clark, Leesa Costello

Research outputs 2022 to 2026

Background: Communities of practice could contribute to transformations in health professions education to meet complex and emerging challenges. However, little is known about the underlying mechanisms of communities of practice in this setting, and how context influences outcomes. Objective: To understand when, why and how communities of practice with health professions education faculty work to facilitate higher education change. Design: A realist synthesis according to the RAMESES standards and steps described by Pawson and colleagues. Review methods: Early scoping of the literature informed the development of an initial program theory to describe underlying assumptions about how communities of practice in …

Danes In Argentina: The Emigration Story Of The Ambrosius Family, Inge Ambrosius

The Bridge

I have had a box of newspaper clippings, letters, pictures, books, and other materials about Danish immigrants in Argentina for many years. Many of my relatives live in Argentina, and the material was assembled by my grandmother and my father. When I retired from teaching high school history and geography, I finally had the time to look at the material. Among other things, the box contained the memoirs of my great-grandfather’s younger brother, Niels Jensen Ambrosius, “Memories of my life and whereabouts in Argentina.” They were written in 1951 when Niels was eighty-four years old. Reading them made me curious, …

Wheat Landraces, Small Farmers And Urban Consumers: Revival Of Einkorn In Turkey, Nurcan Atalan Helicke

Journal of Critical Global Issues

Cultivated for more than 10,000 years, wheat (Triticum) is one of the world’s most widely grown and important crops. Wheat has sustained humans for thousands of years in a multitude of ways. In recent years, there has been a global movement to revive wheat landraces. Landraces are typically adapted to a local area and to traditional farming systems. This article examines the revival of wheat landrace, einkorn (Triticum monoccoccum L. subsp. monoccoccum) through a case study of Turkey. There is limited literature examining the interaction of actors in decision-making processes that balance subsistence and market motivations. …

Socio-Economic Integration Strategies Of “Former Rwandan Refugees” In Yaoundé, Cameroon., Michèle Mc Signé

Journal of Critical Global Issues

This research is entitled The Socio-economic Integration Strategies of “former Rwandan refugees” in Yaoundé, Cameroon. This is an analysis of immigrants who were once under international protection. The presence of former Rwandan refugees in the city of Yaoundé dates back to the time of the 1994 Rwandan genocide. With the advent of the cessation clause in 2018, we are faced with individuals who must find ways of coping with the new realities. Based on the assimilation and integration of immigrant, this study analyzes the integration strategies of former Rwandan refugees. This integration is facilitated by a social context described as …

Panel Session. Science Superheroes: Cultivating Careers In Science And Research, Priyadarshini Chakrabarti Basu, Sydney Murphy, Donna Strum, Eden Tanner, Brandi Newkirk-Turner

WHEMN Conference

This panel features accomplished women scientists and researchers from Mississippi universities. The moderated discussion will include how they cultivated successful careers in their fields; lessons they have learned and how that translates into practical advice for other women; and how they are shaping the future of research and science by mentoring students and other women in their fields.

• Priyadarshini Chakrabarti Basu, assistant professor, Pollinator Health and Apiculture, Mississippi State University
• Sydney Murphy, dean, School of Graduate Studies in Health, University of Mississippi Medical Center
• Donna Strum, dean, School of Pharmacy, University of Mississippi
• Eden Tanner, assistant …

Welcome, Charlotte Fant Pegues

WHEMN Conference

Dr. Charlotte Fant Pegues, WHEMN state coordinator and vice chancellor for Student Affairs at the University of Mississippi, leads a team of professionals who are committed to providing exceptional services and creating an environment where all students can be successful. During her 30 years of service to the university, she has served as assistant vice chancellor for student affairs, director of admissions and assistant provost and registrar. Dr. Fant Pegues earned several degrees from the university including a B.A. in Psychology, an M.A. in Education and a Ph.D. in Leadership and Counselor Education. She holds an academic appointment in the …

Differential Energy Allocation Among 15 New Guineagrass (Panicum Maximum Jacq.) Hybrids, J A. Usberti Jr, R Usberti, R S. Paterniani

IGC Proceedings (1977-2023)

The main aim of this research work was to determine trends of energy allocation among newly developed guineagrass (Panicum maximum Jacq) hybrids, ranging from very-early to late-flowering genotypes. Besides the flowering cycle, eight phenological and two seed quality traits were scored in a greenhouse randomized complete block experiment including plant height (PH), reproductive tiller number/overall tiller number (RTN/OTN), panicle number/reproductive tiller (PN/RT), leaf length (LL), leaf width (LW), panicle length (PL), fresh weight (FW), dry weight (DW), number of seeds/gram (NS/G) and seed sample physical purity (SPP). Very-early and early-flowering hybrids consistently showed the highest correlations values between flowering …

Lodging Resistance Evaluation In Lolium Multiflorum, Katsuo Egara, Kazuhiro Tase, Makoto Kobayashi, Hiroki Fujii

IGC Proceedings (1977-2023)

The objective of this study was to develop a simple technique to evaluate lodging resistance in Italian ryegrass (Lolium multiflorum) for genetic improvement. Significant relationships were recognized between the pushing resistance index and actual lodging degree (ALD), and between the breaking resistance index and ALD, at the 0.1 and 5 percent levels, respectively.

Performance Of Dairy Cows, Feed Quality And N Balance On Pasture Systems With Or Without Mineral N Fertilizer, M Rodehutscord, Ina Hahner, H Spiekers, E Pfeffer

IGC Proceedings (1977-2023)

In a 2 year experiment, two levels of mineral N fertilization (nil and 225 kg N/ha) on pasture were checked for their effects on pasture yield and quality as well as for performance of dairy cows. Twenty six cows were used in each treatment and the stocking density was adapted to previous results on pasture growth rates. Cows were kept on pasture during summer and grass silages were harvested from the respective experimental areas for winter feeding periods. Digestibility of organic matter in these silages, determined in wether sheep, was always higher in those silages harvested from pasture without mineral …