Digital Commons Network^™

Prospects And Challenges Of Library Collaboraton In Changing World, Eze Onwuzurike Jane

Library Philosophy and Practice (e-journal)

The paper investigates the prospects and challenges of library collaboration in the era of global change. It delved into the purpose of establishing libraries and concept of library collaboration. The paper evaluate collaboration as a process where two or more libraries work together to achieve common goals. It analyses collaboration as a global trend where libraries share open resources and engaged in networking activities. It discusses rationale to collaboration by drawing examples from stakeholder engagement, feasibility study, capacity building, people, organization and change. The paper examines prospects of collaboration among libraries which includes application of ICT in collaboration, cost saving, …

Expropriation Of Shares Via The Corporate Constitution, Stephen Bull

Research Collection Yong Pung How School Of Law

Company constitutions sometimes include powers to effect compulsory share acquisitions from members. Where these are introduced into the constitution after incorporation, the amendment, like all constitutional alterations, must be able to satisfy the common law “bona fide test” in order to be valid. The content of this test has been much debated since the first cases a century ago, and differences in view have emerged from the English and Australian courts. While there is no local case law on such expropriations per se, the High Court recently confirmed for the first time the applicability in Singapore of the common law …

Attitudes And Perceptions Towards Privacy And Surveillance In Australia, Aleatha J. Shanley

Theses: Doctorates and Masters

Understanding attitudes towards privacy and surveillance technologies used to enhance security objectives is a complex, but crucial aspect for policy makers to consider. Historically, terrorism-related incidents justified the uptake of surveillance practices. More recently however, biosecurity concerns have motivated nation-states to adopt more intrusive surveillance measures. There is a growing body of literature that supports the public’s desire to maintain privacy despite fears of biological or physical threats.

This research set out to explore attitudes towards privacy and surveillance in an Australian context. Throughout the course of this endeavour, the COVID-19 pandemic emerged bringing with it a variety of track …

Understanding Mental Wellbeing Of Family Day Care Educators In Australia: A Mixed Methods Study, Theresa Rayfield

Theses: Doctorates and Masters

Family Day Care (FDC) is an essential service within the Australian early childhood education and care sector. FDC educators support Australian families who require convenience, flexibility, and versatility in the education and care of their children. FDC educators’ mental wellbeing (MWB) is vital to ensure optimal education and care is provided, however this is often overlooked by educators. This research aimed to gauge Australian FDC educators’ MWB, identify factors positively or negatively affecting MWB and strategies employed to maintain and support MWB.

Primarily, a cross-sectional quantitative questionnaire measuring MWB and ten predictor variables determining relationship with food, food insecurity, alcohol …

Coordinating The Telematic Music Performance Experience With Telemidi: Synchronising Nodes, Enhancing Musicality, And Delivering Simultaneity, Matthew Clive Bray

Theses: Doctorates and Masters

The practice of Telematic Music Performance (TMP), a subset of Network Music Performance (NMP), enables geographically remote musicians to engage in real-time musical interplay, typically occurring over a Wide Area Network (WAN: the Internet). However, the transmission of data between remote collaborators introduces millisecond latencies that obstruct the nuance of traditional human-to-human musical intercourse, and consequentially, the music generated by TMP often lacks rudimentary degrees of syncopation. Reducing network latency has been a critical focal point for research in this field, wherein effective networks support low-latency, multi-modal data transmission to enhance sensations of immersion and telepresence for participants; the sense …

Verbal And Nonverbal Communicative Approaches Used By Reading Teachers To Foster Student Reading For Pleasure In Secondary School, Claire Patricia Smith

Theses: Doctorates and Masters

The benefits of reading for pleasure are diverse. As evidence supporting the value of reading for pleasure grows, so does its legitimacy as a catalyst for positive personal and cognitive development, and as a stand-alone subject in education. Reading for pleasure pedagogy (RfPP), distinct from reading instruction, is evolving in tandem with these findings. This pedagogy is predicated on the profile of a Reading Teacher (RT) as a reader who enjoys reading and is prepared to share their personal reading lives to teach their students to read for pleasure. However, this profile may be an ideal rather than the norm. …

The Experiences Of Older Immigrants Living With Dementia In Australia: A Multi-Method Secondary Analysis, Pelden Chejor

Theses: Doctorates and Masters

The ageing immigrant population and rising dementia cases underscores the need for culturally appropriate dementia care services. However, accessing dementia care services can be challenging for immigrants due to cultural and linguistical differences including their health beliefs. Understanding the experiences and concerns of older immigrants living with dementia is imperative for the planning and delivery of culturally and linguistically appropriate care. The aim of this thesis was to explore and describe the experiences of older immigrants living with dementia, as well as to describe and compare (against non-immigrants living with dementia) the characteristics (neuropsychiatric symptoms and pain characteristics) of older …

Developing A Framework For Musical Ekphrasis In Jazz Composition, Jessica Carlton

Theses: Doctorates and Masters

Musical ekphrasis, as defined by musicologist Siglind Bruhn (2001), refers to musical compositions that transform, re-create, or ‘re-present’ a work of visual art or poetry. Though there exists a significant body of musical works that are based on visual art and poetry, there is a distinct lack of research and documentation on musical ekphrasis, particularly in the field of jazz and improvised music. Further, a formalised process framework for practitioners approaching ekphrastic composition has yet to be developed. This research project investigated musical ekphrasis through qualitative interviews with key practitioners, and a combination of practice-led research and research-led practice methodologies, …

A Model Defense Of Due Process Balancing, Kyron J. Huigens

Articles

Judicial balancing has been subjected to a standard list of objections for decades, without anyone's offering a comprehensive and persuasive response. This Article fills that gap. Balancing is not embedded in an invidious instrumentalism, such as utilitarianism, that saps law of its moral salience; it does not depend on the quantification or commensuration of manifestly qualitative legal interests; it is not arbitrary, result-oriented, or mere opinion; it does not invade the province of the legislature; and--most importantly--it does not risk balancing constitutional rights away by treating them as mere interests.

The defense consists of a model. Models do not prove; …

Sails Symposium Launch On International Law Scholarship: What We Write, Where We Publish, And Why It Matters, Kathleen Claussen, Melissa J. Durkee, Rebecca Ingber, Steven Arrigg Koh

Articles

No abstract provided.

Improving The Affirmative Disclosure Of Agency Legal Materials, Bernard W. Bell, Cary Coglianese, Michael E. Herz, Margaret B. Kwoka, Orly Lobel

Articles

It is axiomatic that in a democratic society the law must be broadly accessible. Administrative agencies produce a plethora of materials imposing legal obligations on commercial or individual actors in the private sector. Other materials bind the agencies themselves in ways that affect the rights or interests of private parties. Still other materials provide the public with information about how agencies interpret and apply the statutes and rules they administer, or how agencies seek to deploy their discretion or take other actions that can affect private individuals or organizations. This Article focuses on improving the public availability of all of …

Characterization Of The Disease-Causing Mechanism Of Kif3b Mutations From Ciliopathy Patients, Jessica M. Adams, Caleb Sawe, Skye Rogers, Jordyn Reid, Ronith Dasari, Martin F. Engelke

Faculty Publications – Biological Sciences

The heterodimeric kinesin-2 motor (KIF3A/KIF3B with accessory protein KAP3) drives intraflagellar transport, essential for ciliogenesis and ciliary function. Three point mutations in the KIF3B subunit have recently been linked to disease in humans (E250Q and L523P) and Bengal cats (A334T) (Cogné et al., Am. J. Hum. Genet., 2020, 106, 893–904). Patients display retinal atrophy and, in some cases, other ciliopathy phenotypes. However, the molecular mechanism leading to disease is currently unknown. Here, we used Kif3a−/−;Kif3b−/− (knockout) 3T3 cells, which cannot make cilia, to characterize these mutations. While reexpression of KIF3B(E250Q) and KIF3B(L523P) did not rescue ciliogenesis, reexpression …

Examining Differences In Self-Concept And Language Between Monolingual And Bilingual Undergraduate Students, Marilyn Vega-Wagner

University of the Pacific Theses and Dissertations

The literature is lacking in studies that examine self-concept and language status among individuals older than adolescence. The purpose of this study is to conduct a quantitative nonexperimental comparative design to examine differences in self-concept and language status (monolingual or bilingual) between male and female undergraduate students in California. A total of 97 participants were examined in the study. The researcher conducted descriptive statistics on the demographics as well as a MANOVA and an ANOVA to answer the proposed research question. Based on the findings presented, the researcher failed to reject the null hypothesis of research question 1: There is …

The Decline Of Science In The Early Years: A Diagnosis And A Plan Of Action, Jennifer Bentley

University of the Pacific Theses and Dissertations

Science instruction in the early years of a student’s education career is essential to a student successfully continuing science in their secondary and postsecondary careers. However, the amount of high-quality science instruction students receive at the elementary level has been steadily declining for two decades, resulting in an inequitable imbalance in those who pursue STEM careers, a lack of critical science literacy in the U.S. populace, and a shortage of qualified employees entering the U.S. economy. Much of the lack of science instruction can be traced to decreased training of teachers to teach science during elementary credentialing programs or the …

Effects Of Fetal Bovine Serum On The Proteome And Secretome Of Pichia Pastoris, Kenneth L. Nguyen

University of the Pacific Theses and Dissertations

Komagataella pastoris, formerly known as Pichia pastoris, and hereafter referred to as Pichia, is a methylotrophic yeast widely employed as a recombinant protein factory for biotechnical and industrial purposes. P. pastoris boasts the ability to thrive at high cell densities, executes numerous post-translational modifications, and exhibits minimal secretion of endogenous proteins, thus greatly facilitating the expression and purification of recombinant proteins. Despite these advantages, Pichia still presents certain challenges as an expression system. Occasionally, recombinant proteins are retained within the cell and subject to degradation. Furthermore, Pichia falls short in matching the production capabilities of more widely used systems like …

The Role Of The Unfolded Protein Response In Fatty Liver Disease, Anusha L. Murshed

University of the Pacific Theses and Dissertations

The unfolded protein response (UPR) is composed of three highly conserved pathways (ATF6, IRE1, PERK). Cellular stressors induce protein misfolding and aggregation in the endoplasmic reticulum (ER). This signaling pathway maintains protein homeostasis when there is stress in the ER. When the UPR is activated, the eukaryotic initiation factor 2 alpha (eIF2α) becomes phosphorylated, which inhibits global mRNA translation. If ER stress remains chronically unmitigated, the UPR induces apoptosis. GADD34 and CReP shift in expression when the UPR is activated and work as phosphatases and dephosphorylate eIF2α in a feedback loop, allowing protein synthesis to resume. Several human diseases, including …

Structural And Functional Studies Of The Human Members Of The Macrophage Migration Inhibitory Factor Family, Andrew Parkins

University of the Pacific Theses and Dissertations

Macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase (D-DT) are the two human members of the MIF superfamily, which are implicated in an array of autoimmune disorders, inflammatory diseases, and cancer via their pleiotropic functionality. Despite only sharing 34% sequence identity, MIF and D-DT have high structural homology and overlapping functional traits, including activation of the type II cell surface receptor CD74 and keto-enol tautomerase activity. The MIF and/or D-DT-induced activation of CD74 leads to signaling cascades pivotal for cell growth, proliferation, and inhibition of apoptosis. Such characteristics make MIF and D-DT attractive molecular targets for drug discovery.

Currently, all …

Swipe Up And Break Up: A Grounded Theory Study Exploring The Impact Of Tiktok On Adolescents’ Perceptions Of Love And Romantic Relationships, Amitoj Sandhu Kaur

University of the Pacific Theses and Dissertations

Adolescence is a time period when major developments occur with respect to adolescents’ physical, emotional and cognitive capabilities, and such developments ultimately make it a pivotal time for a person’s identity formation and understanding of interpersonal relationships. In today’s world, social media is extremely popular, especially among adolescents, and it has influenced their behaviors, perceptions and interactions with others. With TikTok, a social media platform, gaining popularity in recent years and overwhelmingly so among adolescents, researchers began researching the general impact of TikTok on adolescents’ mental health. Some researchers have begun exploring niche research topics related to the impact of …

Impact Of Drug-Polymer Interactions On Stability In Simvastatin-Based Amorphous Solid Dispersions, Charina Lampa

University of the Pacific Theses and Dissertations

This study aimed to investigate the drug-polymer interactions between simvastatin (SIM) and three polymers [PVP-VA, HPMC-AS, and Soluplus® (SOL)] in amorphous solid dispersions (ASDs) prepared by hot melt extrusion (HME), and to understand the implications on physical stability. ASDs are of significant interest within the pharmaceutical industry for improving drug bioavailability. However, the amorphous nature of a drug in an ASD presents physical stability challenges. Utilizing novel applications of accessible tools such as ATR-FTIR or DSC aid in understanding the mechanisms of stabilization which are critical to the rational design of ASDs. ASDs were prepared using HME and were characterized …

Why Would I Read When The Game Is On?: Reasons Adults Give For Reading Or Not, Emmy C. Nelson

Honors Program Theses

This thesis dives into the ideas of why people read and do not read, beginning in their childhood years. Many different factors add to why people choose to read or why they choose not to read. School plays an important role as to why people choose to read because reading is not necessarily a natural process since it is different from learning how to speak. Reading has to be taught and understood fully in order to read independently, understand the material, expand ideas, and connect with the reading. Without this, individuals can become “poor” readers or have a low reader …

A Literature Review Of Factors Contributing To Archaeal Diversity, Anna R. Carmen

Honors Program Theses

Archaea, being classified as its own separate domain only within the past fifty years, has earned a reputation of being notoriously difficult to culture in a laboratory setting. Because of this, their functions in ecosystems and potential for use in bioremediation is largely unknown and untapped. In order to further develop methodologies to successfully cultivate these microbes, an analysis of past research is needed to help understand where to lead research. After analyzing past studies on archaea and recalcitrant microbes as a whole, it is found that other factors are often overlooked and a label of recalcitrance is added. This …

Little Miss Sure Shot: Essays On A Young Woman Journalist's Search For Fulfillment, Mallory Schmitz

Honors Program Theses

No abstract provided.

Balancing Progress And Ethics: Exploring The Science And Ethics Of Gene Editing: Literature Review, Jackson Burgess

Honors Program Theses

Two decades ago, the completion of the Human Genome Project marked a pivotal milestone in scientific history, unraveling the blueprint of human DNA and laying the foundation for the Genetic Revolution. This monumental achievement allows researchers to uncover the correlations between DNA sequences and biological functions. Today, this movement has propelled modern geneticists toward the peak of human health sciences: the ability to manipulate the very essence of our being. With the aid of Genetic Engineering, scientists now possess the capability to alter the fundamental framework of our genetic code, offering the potential to cure fatal genetic disorders alongside other …

Beyond The Classroom: Do The Iowa Civic Virtues Standards Achieve Their Goals?, Damien Foster

Honors Program Theses

Civic education is essential in shaping informed and active citizens, and evaluating its impact is equally as fundamental. This study examines the connection between the Iowa civic virtues standards and the civic behaviors and attitudes of recent high school graduates. Through an online survey of college students in Iowa, findings suggest that while the standards effectively communicate civic values, there is a gap in translating this knowledge into practical engagement, particularly in political participation. Additionally, the rising influence of digital media on students' political decisions highlights the need for enhanced digital data and information literacy education. This study provides many …

The Impact Of Covid-19 On The It Services Industry, Shekynah Annemarie Haworth

Honors Program Theses

The COVID-19 pandemic has caused significant disruptions across industries worldwide, and the information technology (IT) industry has been no exception. As IT professionals continue to face unprecedented challenges due to the pandemic, it is essential to understand the current effects of COVID-19 on the IT services sector and what the future may hold. This study aims to provide an up-to-date understanding of how the pandemic has influenced the IT services sector by conducting an in-depth survey among IT professionals. The research will primarily focus on the persistent challenges faced by IT professionals during the pandemic and what changes have occurred …

Death And Grief In 21st Century America: A Literature Review On Bereavement & Attitudes Toward Death, Jordan Whitney

Honors Program Theses

In modern Western society, death has been dissected and neatly packaged like meat at the grocery store. The unsavory aspects are hidden and our discomfort around dying has turned death into a commodity. In typical consumerist fashion, we are sold the “proper way” to die and grieve as a result. Funeral homes guide us through this new experience with the goal of assisting us through our grief. While most report positive experiences with funeral directors’ services, there remains evidence of overcharging and pressuring into the purchases of unnecessary additional services. This thesis explores modern attitudes and practices towards death, grief, …

We Did What? To Whom? An Analysis Of How Us Educational Materials Present The Philippine-American War And Occupation, Jude Beekman

Honors Program Theses

Since the turn of the 21st century, decisions of American leaders have continued traditions of American exceptionalism and general attempts at dominance, although this is continuously brought into question. A generation has since passed through school and experienced curriculums that have implied such American exceptionalism and dominance. Acknowledged for decades, the military-industrial complex has extended into the 21st century with involvement across the globe, but notably in the Middle East. For those indigenous to the Pacific, militarism extends to how people perceive the bodies and selves of indigenous peoples. There exist multiple definitions of colonialism and imperialism, but in essence, …

Why Play? Exploring The Realities Of Play-Based Learning In Kindergarten, Sofia Josephine Steele

Honors Program Theses

By nature, children are curious and love to explore the world around them. Play is one way that children can fulfill that innate curiosity. Through play-based learning, educators can utilize that innate curiosity and wonder in children to create valuable learning experiences that will engage and teach them. This pedagogical approach is used in early childhood education to help children develop their academic, social, and emotional skills through appropriate learning experiences that consider their abilities and interests. However, in recent years, there has been a shift away from play-based learning in kindergarten classrooms. The reasoning behind this shift may be …

The Role Of Flo11 In Saccharomyces Cerevisiae Colonization Of The Lepidopteran Gastrointestinal Tract, Kayla Jeanette Minor

Honors Program Theses

No abstract provided.

A Critical Evaluation Of "Leakage" At The Cochlear Blood-Stria-Barrier And Its Functional Significance, Kevin K Ohlemiller, Noël Dwyer, Veronica Henson, Kaela Fasman, Keiko Hirose

2020-Current year OA Pubs

The blood-labyrinth-barrier (BLB) is a semipermeable boundary between the vasculature and three separate fluid spaces of the inner ear, the perilymph, the endolymph and the intrastrial space. An important component of the BLB is the blood-stria-barrier, which shepherds the passage of ions and metabolites from strial capillaries into the intrastrial space. Some investigators have reported increased "leakage" from these capillaries following certain experimental interventions, or in the presence of inflammation or genetic variants. This leakage is generally thought to be harmful to cochlear function, principally by lowering the endocochlear potential (EP). Here, we examine evidence for this dogma. We find …