Digital Commons Network^™

Comparative Enzymatic Analysis Of Different Isoforms Of Group A Streptococcal Bacteriophage H4489a Hyaluronidase, Urvi Prakash Rawal

All ETDs from UAB

The Hyaluronate Lyase derived from Group A streptococcal bacteriophage H4489A gene (HylP) is known for cleaving the glycosidic bonds of high molecular weight hyaluronic acid (HMWHA), a substance often overexpressed in certain types of cancer cells. This enzymatic action produces HA oligosaccharides. Previous research, conducted by our team, has demonstrated that these oligosaccharides play a significant role in reducing the invasion, migration, and proliferation of breast cancer cells. This effect occurs through the disruption of Erk1/2 activation and RhoA expression. This bacteriophage hyaluronate lyase (HylP), a 40kDa protein, possesses a unique collagen-like sequence, consisting of 30 amino acids in a …

Associations Of Religious Involvement And Cultural Justifications With Depressive Symptoms And Burden Among Caregivers, Maizonne Fields

All ETDs from UAB

With the advancement of medicine, life expectancy has increased globally. As a result, the need for a caregiver by an older adult has also risen. A caregiver is often a spouse, child, or friend of an older adult that assists an older adult that is experiencing changes in their ability to complete activities of daily living and/or instrumental activities of daily living. Caregivers are often unpaid for their assistance and can be at heightened risk for negative mental health outcomes. This study used the Stress Process Model to investigate the associations of high levels of religious commitment or involvement (RCI) …

Mixed Martial Arts, Meaning, And Behavioral Peace: Examining Social Relationships In A Diverse Environment, Dana Dawson

All ETDs from UAB

This thesis investigates the manifestation of behavioral peace within the diverse subcultures of mixed martial arts (MMA) gyms, drawing from the operational definition provided by peace ethology, which encompasses more than just the absence of violence. Peace ethology investigates how behavioral peace is achieved through mutual interests, tolerance, helping, sharing, and the avoidance of aggressive confrontation. This thesis explores how behavioral peace manifests in environments characterized by controlled violence and vulnerability, focusing on three MMA gyms in Alabama. Employing an ethnographic and ethological framework, the methodology blends autoethnography with participant observations and semi-structured interviews to comprehend the cultural, environmental, and …

Physiologically Relevant Cardiac Tissue Chips For Cardiovascular Disease Modeling, Sachin Budhathoki

All ETDs from UAB

Despite significant advances in our understanding of the molecular basis of cardiovascular diseases (CVD) and the development of new therapeutics, it remains the number one cause of death worldwide, particularly affecting the aging population. This necessitates the development of models that can more accurately recreate aspects of aging and the interaction of the heart with other organs and systems in the body, including the immune system. Tissue chip models are being increasingly considered for studying cardiac diseases as they can potentially address translational hurdles associated with animal models, yet several challenges hinder their full potential. These include a lack of …

The Effect Of The Chemical And Physical Properties Of Cotton On The Retention Of Spermatozoa, Brynnen Hendrix

All ETDs from UAB

Studies have shown that spermatozoa persist on cotton fabric under various conditions after being washed multiple times. The purpose of this study was to observe the number of sperm cells removed from cotton fabric over the course of multiple wash cycles. This study also explored how various treatment methods impact the rate of removal and number of cells removed. In this study, sperm cells were counted using a hemacytometer to estimate the average number of cells in a 20 µL semen stain. Twenty stains were prepared on cotton fabric and washed in a microfuge tube with 200 µL of reverse …

Fentanyl Overdoses And Use Of Randox Multistat For Investigative Purposes, Clarissa Danielle Lawen

All ETDs from UAB

The opioid epidemic started in the early 1990s with the rise of prescription overdoses. In more recent years, heroin and fentanyl use has rapidly increased. Fentanyl, specifically, is 50 to 100 times more potent than morphine. To keep up with the ever-evolving epidemic, the Randox MultiSTAT was validated for use in the medical examiner autopsy suite for the potential to aid medical examiners in triaging the need for a full autopsy versus an external examination with toxicology testing. The Randox MultiSTAT is a triage tool and investigatory screen designed to provide presumptive test results across multiple matrices. It can detect …

Effect Of Fluid Elasticity On The Emergence Of Oscillations In An Active Elastic Filament, Kathryn G. Link, Robert D. Guy, Becca Thomases, Paulo E. Arratia

Mathematics Sciences: Faculty Publications

Many microorganisms propel themselves through complex media by deforming their flagella. The beat is thought to emerge from interactions between forces of the surrounding fluid, the passive elastic response from deformations of the flagellum and active forces from internal molecular motors. The beat varies in response to changes in the fluid rheology, including elasticity, but there are limited data on how systematic changes in elasticity alter the beat. This work analyses a related problem with fixed-strength driving force: the emergence of beating of an elastic planar filament driven by a follower force at the tip of a viscoelastic fluid. This …

The Exclusion Of Black Girls: A Quantitative Study, Ursula Moorer

Selected Full Text Dissertations, 2011-

Existing research consistently indicates that Black girls are assigned disproportionately exclusionary disciplinary consequences such as, suspension and expulsion rates, surpassing their White counterparts and Black boys. According to the Report to Congressional Requesters, (United States Governmental Accountability Office, 2018), exclusionary discipline is any type of removal from a student’s normal educational setting. This quantitative correlational study examined the relationship between the racial demographics within a school's student and personnel populations and occurrences of suspensions faced by Black female students in grades 9 through 12. Archival data were used from the New York State Education Department (NYSED) website. NYSED data are …

Implementation And Promotion Of Digital Citizenship In K-12 Schools: A Case Study Of Selected Schools On Long Island, New York, Seema Sumod

Selected Full Text Dissertations, 2011-

The advances in technology in the past decades have revolutionized the field of K-12 education, and its widespread implementation has given rise to the concurrent need to educate students about its responsible usage. The concept of digital citizenship as applicable to schools includes elements like digital access, digital communication, digital literacy, digital etiquette, digital rights and responsibilities and digital security. This study examined how twelve randomly selected school districts in the Long Island region of New York presented and promoted digital citizenship on their websites. A content analysis of these school district websites was conducted to identify which elements of …

School Monitors: A Quantitative Study On The Support Needed For These Professionals, Sara Goldberg

Selected Full Text Dissertations, 2011-

Minimal research has been focused on the role of school monitors in the public-school setting. This study explored the perspectives of school monitors on preparation, training, communication, and feedback. The study looked to examine if these aspects contribute to the overall role of school monitors and to identify specific areas where they require guidance and support to assist students throughout their day. Additionally, the study determined if schools who use a social emotional curriculum have school monitors who feel more supported in their role. Preparation, support, communication, and feedback was investigated using a 27 statement Likert-scale survey and three open-ended …

Digital Transformations In The Hotel Industry, Mehmet Sanli

Selected Full Text Dissertations, 2011-

New technologies are changing the way business is done in the hospitality industry. This research explores the emerging field of technology in the hotel industry. This research examines the significant influence of Information Communication Technology (ICT) in driving digital transformations in the hotel industry. With the evolution of the global hospitality sector, the in-corporation of advanced digital technologies has become essential for hotels aiming to elevate customer experiences, operational efficiency, and overall competitiveness. The research observes key components of digital transformation in the hotel industry, including but not limited to online booking systems, mobile applications, data analytics, the Internet of …

1. Introduction To Special Edition, John Pender, Perry Share

Irish Journal of Applied Social Studies

No abstract provided.

4. Robotic Babies - Data, Didactics And Ethics In Social Work, Mads Lund Andersen, Vivi Friis Søgaard, Karin Christiansen, Heike Felzmann, Almundena Navas, Miriam Abietar

Irish Journal of Applied Social Studies

No abstract provided.

6.Can Social Robot Teaching Assistants Innovate The Irish Primary Education System, John Pender, Debbie Woodward

Irish Journal of Applied Social Studies

No abstract provided.

The Relationship Between Familiarity And Stigma Associated With Schizophrenia, Bipolar Disorder, And Autism In Ireland: A Pilot Study, April Hargreaves, Gerard Loughnane, Gabriela Grasso, David Mothersill

Irish Journal of Applied Social Studies

The relationship between familiarity with mental health conditions and mental health stigma is complex, with mixed findings reported in the literature and little research conducted in Ireland to date. This pilot study examined knowledge, attitudes, and behaviours towards schizophrenia, bipolar disorder, and autism in Ireland, between individuals personally familiar with these conditions (by having a diagnosis themselves, or a loved one having a diagnosis) and individuals unfamiliar with these conditions. The study used a correlational, cross-sectional design, recruiting 307 adults in Ireland to complete a survey examining knowledge, attitudes, and behaviours towards schizophrenia, bipolar disorder, and autism. To examine the …

“I Know A Lot Of People Just Gave Up And Died, Out Of Loneliness”: Family Members Experiences Of Covid-19 Visitation Restrictions In Irish Nursing Homes, Emily Egan, Sarah Robinson, Erin Nic An Bhaird, Graham Gillespie

Irish Journal of Applied Social Studies

COVID-19 has had a disproportionate impact on older adults, particularly those living in nursing homes (NH) globally and in Ireland, the site of our study. Whilst NH residents were at increased risk of serious illness from the virus, visitation bans and restrictions also impacted residents' quality of life. Family members' (FMs) essential caring role was recognised in contexts like the Netherlands, parts of the United States and Ontario, Canada, but were not in Ireland. The current study explored the experiences of FMs of residents who experienced visitation bans during the first four waves of the COVID-19 pandemic in Ireland. Eight …

Risk Factors As Indicators For Online Child Sexual Abuse: A Systematic Review, Lesley Lally, Isobel Webb, Ethel Quayle

Irish Journal of Applied Social Studies

Abstract

Introduction: Online child sexual abuse has been described as a serious public health issue worldwide in today’s society. The long-term consequences of such abuse have been well-reported, and the risks in which youth are made more vulnerable to this abuse must be better understood.

Objective: To synthesise and evaluate the literature regarding risk factors of online sexual exploitation by focusing on the following question: What are the risk factors that make children vulnerable to online child sexual abuse and solicitation?

Method: A systematic review was completed using search strings within several databases, a hand search was conducted, and …

The Cost Of Caring – Understanding Psychological Distress In Support Staff Who Work With Adults With An Intellectual Disability In Ireland., Deirdre Mullins Ms, Dr. Christopher Mccusker

Irish Journal of Applied Social Studies

Background: Evidence suggests that levels of psychological distress are elevated in staff who support people with challenging behaviour (CB) and intellectual disability (ID) in residential care. However, in Ireland, there has been little research examining the extent of this and determinants thereof. Specific Aims: This study explored psychological functioning and workplace related quality of life, and factors associated with such, in support staff in Ireland. Method: 109 participants were recruited through a social media platform. Levels of stress, depression, anxiety and work-related quality of life were assessed using standardised measures. A bespoke questionnaire assessed key work-related factors such as …

Happy To Zoom: A New Frontier In Online Delivery Of Day-Care For Older People During Covid-19, Suzanne C. Smith Msc, Holly O'Brien, Darragh Mccashin Phd

Irish Journal of Applied Social Studies

From early in the COVID-19 pandemic, community day-care centres sought to find ways to deliver services remotely using digital tools, but older people are often presumed resistant to using digital technologies. This study sought to examine the delivery of community day-care services at the beginning of the COVID-19 pandemic and to identify the willingness of older service users to participate in day-care activities remotely while in-person services were unavailable. Community day-care services are essential to ensuring social participation and overall wellbeing for many older people who remain living at home. On March 16^th, 2020, like many other services, …

Development Potential Of Smes In Poland Selected Aspects Of Age, Diversity And Intellectual Capital Management, Elwira Gross-Gołacka, Izabela Warwas, Justyna Wiktorowicz

Monografie/Monographs

Monografia o charakterze teoretyczno-empirycznym przybliża funkcjonowanie małych i średnich firm w Polsce przez pryzmat wybranych aspektów kapitału ludzkiego. Autorzy szczególną uwagę poświęcili zaprezentowaniu determinant rozwoju oraz czynników sukcesu małych i średnich przedsiębiorstw, roli kapitału ludzkiego w budowaniu trwałej przewagi konkurencyjnej przedsiębiorstw oraz prezentacji różnorodnych zasobów i relacji pomiędzy kapitałem intelektualnym a zarządzaniem różnorodnością

This theoretical and empirical monograph presents the functioning of small and medium-enterprises in Poland through the prism of selected aspects of human resources. The authors devote particular attention to presenting the determinants of development and success factors of small and medium-enterprises, the role of human resources capital …

Od Społecznej Odpowiedzialności Do Esg W Zarządzaniu. Wybrane Aspekty, Karolina Łudzińska

Monografie/Monographs

Monografia poświęcona problematyce społecznej odpowiedzialności przedsiębiorstw z perspektywy uwzględniania kryteriów ekologicznych, społecznych i zarządczych (kryteriów ESG) wobec potrzeb i oczekiwań interesariuszy. Publikacja zarysowuje rozwój idei społecznej odpowiedzialności i jej implementacji, zwłaszcza w kontekście integracji czynników ESG przez przedsiębiorstwa i rynki kapitałowe. Przedstawiono w niej aktualne informacje i wyniki badań, a także najnowsze wytyczne dotyczące raportowania niefinansowego. Szczególny nacisk położono na ewolucję integracji czynników ESG na rynku polskim, uwzględniając aspekty takie jak inwestowanie społecznie odpowiedzialne, indeksy ESG na Giełdzie Papierów Wartościowych w Warszawie oraz obecny stan raportowania niefinansowego w Polsce. Korzystając z różnych metod badawczych, publikacja zapewnia kompleksowy zbiór analiz na …

Examining How Non-Antifungal Medications Impact Host-Fungal Interactions, Parker Ryan Reitler

Theses and Dissertations (ETD)

Invasive fungal infections (IFIs) are estimated to kill 1.5 million people each year with mortality rates remaining high (around 30-70%), despite the availability of three major classes of antifungal drugs. Furthermore, millions more suffer debilitating infections of the mucosal membranes or destructive subcutaneous mycoses. One of the most common IFIs is invasive candidiasis, mostly commonly caused by Candida albicans infections, with mortality rates of approximately 30%. In addition, the population of susceptible individuals and the incidences of both mucosal and systemic mycoses continue to rise due to the widespread use of broad-spectrum antibacterial agents, cancer chemotherapies, and the immune suppressive …

Biomechanical Outcomes Of Distinct Tka Surgical Alignments And Implant Designs, Alexis Kathleen Nelson-Tranum

Theses and Dissertations (ETD)

Introduction. Total knee arthroplasty (TKA) has advanced over the past two decades from traditional post-operative neutral alignment methods with an overall goal of implant longevity to ones that are more personalized to better replicate individual native knee kinematics. Personalizing TKA knee kinematics to better replicate a patient’s native knee kinematics has evolved in response to a reported 20% dissatisfaction by patients with their TKA. These personalization advancements include innovations in surgical alignment techniques include the kinematic alignment (KA) and joint line obliquity (JLO) restoration, in contrast to the mechanical alignment (MA) technique that places everyone into the same mold. Additionally, …

Ftsk Regulates The Assembly Of The Division Machinery In The Ftsz-Less Chlamydia Trachomatis, Mckenna Katherine Harpring

Theses and Dissertations (ETD)

In evolving to obligate intracellular dependence, Chlamydia trachomatis serovar L2 (Ct), has eliminated several gene products essential for cell division in most other bacteria, including FtsZ, the central coordinator of divisome assembly. In the absence of FtsZ, we show that divisome assembly in Ct is initiated by FtsK, a chromosomal translocase. Chlamydial FtsK forms discrete foci at the septum and at the base of the progenitor mother cell, and our data indicate that FtsK foci at the base of the mother cell mark the location of nascent divisome complexes that form at the site where a daughter cell will emerge …

Optical Absorption Of Defects In Aluminum Nitride, Mackenzie Siford

All ETDs from UAB

Aluminum nitride (AlN) is an ultrawide bandgap semiconductor material known for its applications in high power microelectronic and optoelectronic devices due to its high thermal conductivity and high electrical resistivity. Point defects are known to hinder the material’s properties and are therefore a subject of interest in semiconductor materials research. The samples used in this work were grown by physical vapor transport (PVT) at Hexatech and they exhibit amber and clear coloration as well as a nonuniformity of charge, which was investigated. Experiments were carried out by electron paramagnetic resonance (EPR) and photo-EPR spectroscopy in order to detect the defect …

Displaced Worker Angst And Far Right Populism, Thomas E. Lambert

Faculty and Staff Scholarship

Background

Nothing causes more anguish and frustration than downward social mobility such as that experienced by less-educated workers and especially by displaced workers. Those who lose economic status lose more than income because they become so socially isolated that they are further frustrated through loneliness (Case and Deaton 2020). Hanna Arendt points out that lonely men are susceptible to authoritarian influence (1973, p. 475).

There is yet another aspect to the downward social mobility of low skilled men, namely that they are losing ground not only relative to social norms but also relative to the wages of low-skilled women. In …

Content Moderation Regulation As Legal Role-Scripting, Sari Mazzurco

Faculty Journal Articles and Book Chapters

Lawmakers and scholars concerned with content moderation regulation typically appeal to "analogies" to justify or undermine different forms of regulation. The logic goes: law should afford individuals due process rights against speech platforms because speech platforms are "like" speech governors as a matter of objective reality. Other common analogies include common carriers, publishers, distributors, shopping malls, and bookstores. Commentators attempt to invoke social roles to understand what the content moderation relationship is, what behaviors are "right" and "wrong" within it, and how law should police behavioral deviations. But they do so without relying on foundational sociology theory that explains what …

Ghost-Hunting In Ai And The Law, Meghan J. Ryan

Faculty Journal Articles and Book Chapters

Generative AI is booming. This technology offers amazing opportunities for growth in various business sectors and creates the opportunity for swift progress on medical innovations, climate change, world hunger, and innumerable other areas. AI also poses a number of challenges, though, such as replacing human workers and exacerbating pernicious biases. Another major concern about generative AI is singularity-the idea that this technology could surpass human intelligence and subjugate us or render us extinct. Although some commentators discount this possibility, the fact that AI experts such as Geoffrey Hinton, Sam Altman, and Elon Musk share the singularity concern should at least …

The Law Of The New Musical Author, Eyal Brook

Cardozo Arts & Entertainment Law Journal

The process of musical creation has been transformed materially in the Digital Age due to technological developments, both regarding the technologies for making music and regarding novel stylistic developments. New musical practices, based on novel technology, afford entirely new modes of creative authorship. The effects of such shifts have redefined the nature of music and the role of musicians in fundamental ways. This article opens a new debate regarding the identity ofthe new musical author and the changes to the musical creative process.

As such changes have impacted the musical creative process, there are necessary changes required to adapt the …

Satire And Actual Malice: Expanding The Reasonable Reader Analysis For The Modem Era, Cory Crystal

Cardozo Arts & Entertainment Law Journal

No abstract provided.